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Receptor
PDB id Resolution Class Description Source Keywords
5LLB 1.92 Å EC: 2.7.4.1 STRUCTURE OF POLYPHOSPHATE KINASE 2 FROM FRANCISELLA TULAREN AMPPCH2PPP AND POLYPHOSPHATE FRANCISELLA TULARENSIS SUBSP. TULARENS(STRAIN SCHU S4 / SCHU 4) COMPLEX WITH NON-HYDROLYSABLE ATP ANALOGUE. POLYPHOSPHATE MENUCLEOTIDE METABOLISM TRANSFERASE
Ref.: SUBSTRATE RECOGNITION AND MECHANISM REVEALED BY LIG POLYPHOSPHATE KINASE 2 STRUCTURES. PROC. NATL. ACAD. SCI. V. 115 3350 2018 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG B:302;
C:302;
D:302;
A:302;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
CL D:301;
B:301;
C:301;
A:301;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
35.453 Cl [Cl-]
6YZ D:303;
B:303;
A:303;
C:303;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
665.168 C11 H20 N5 O18 P5 c1nc(...
6YW D:304;
A:304;
C:304;
B:304;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
497.895 H8 O19 P6 OP(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LLB 1.92 Å EC: 2.7.4.1 STRUCTURE OF POLYPHOSPHATE KINASE 2 FROM FRANCISELLA TULAREN AMPPCH2PPP AND POLYPHOSPHATE FRANCISELLA TULARENSIS SUBSP. TULARENS(STRAIN SCHU S4 / SCHU 4) COMPLEX WITH NON-HYDROLYSABLE ATP ANALOGUE. POLYPHOSPHATE MENUCLEOTIDE METABOLISM TRANSFERASE
Ref.: SUBSTRATE RECOGNITION AND MECHANISM REVEALED BY LIG POLYPHOSPHATE KINASE 2 STRUCTURES. PROC. NATL. ACAD. SCI. V. 115 3350 2018 U.S.A.
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5LLB - 6YZ C11 H20 N5 O18 P5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5LLB - 6YZ C11 H20 N5 O18 P5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5LLB - 6YZ C11 H20 N5 O18 P5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 6YZ; Similar ligands found: 339
No: Ligand ECFP6 Tc MDL keys Tc
1 6YZ 1 1
2 ACQ 0.909091 1
3 ACP 0.833333 1
4 HEJ 0.833333 0.972222
5 ATP 0.833333 0.972222
6 AQP 0.822785 0.972222
7 5FA 0.822785 0.972222
8 ADP 0.818182 0.972222
9 AP5 0.794872 0.945205
10 B4P 0.794872 0.945205
11 BA3 0.782051 0.945205
12 A2D 0.779221 0.945205
13 APC 0.756098 0.986301
14 AT4 0.740741 0.933333
15 AN2 0.740741 0.958904
16 M33 0.731707 0.932432
17 TAT 0.729412 0.933333
18 T99 0.729412 0.933333
19 SAP 0.72619 0.921053
20 AGS 0.72619 0.921053
21 AMP 0.717949 0.944444
22 A 0.717949 0.944444
23 APR 0.714286 0.945205
24 AR6 0.714286 0.945205
25 ANP 0.709302 0.945946
26 AD9 0.705882 0.945946
27 A12 0.695122 0.986301
28 AP2 0.695122 0.986301
29 25L 0.691489 0.958904
30 CA0 0.690476 0.92
31 ADX 0.690476 0.851852
32 50T 0.682353 0.932432
33 PRX 0.674419 0.87013
34 ATF 0.674157 0.933333
35 ABM 0.670732 0.893333
36 A22 0.67033 0.958904
37 RBY 0.666667 0.959459
38 ADV 0.666667 0.959459
39 4TC 0.660194 0.922078
40 ADQ 0.655914 0.92
41 SRA 0.646341 0.894737
42 5AL 0.644444 0.906667
43 A3R 0.638298 0.909091
44 A1R 0.638298 0.909091
45 AU1 0.632184 0.945946
46 7D4 0.632184 0.881579
47 SRP 0.630435 0.907895
48 ADP PO3 0.629214 0.917808
49 25A 0.62766 0.945205
50 OAD 0.625 0.92
51 9X8 0.625 0.896104
52 4AD 0.621053 0.921053
53 2A5 0.617977 0.92
54 G5P 0.617647 0.897436
55 00A 0.614583 0.860759
56 ITT 0.613636 0.917808
57 3OD 0.612245 0.92
58 BIS 0.612245 0.909091
59 5SV 0.610526 0.82716
60 OOB 0.610526 0.906667
61 8QN 0.610526 0.906667
62 G3A 0.607843 0.897436
63 7D3 0.604651 0.881579
64 HFD 0.604396 0.921053
65 AMO 0.604167 0.933333
66 PAJ 0.604167 0.8625
67 MAP 0.6 0.921053
68 AHX 0.597938 0.897436
69 DLL 0.597938 0.906667
70 GTA 0.596154 0.864198
71 PTJ 0.59596 0.873418
72 UP5 0.59434 0.896104
73 PAP 0.593407 0.958333
74 ATR 0.593407 0.944444
75 3UK 0.591837 0.894737
76 AFH 0.586538 0.886076
77 B5V 0.585859 0.883117
78 WAQ 0.585859 0.884615
79 LAD 0.585859 0.8625
80 PR8 0.585859 0.851852
81 ADP ALF 0.585106 0.848101
82 ALF ADP 0.585106 0.848101
83 SON 0.58427 0.933333
84 GAP 0.580645 0.87013
85 TXA 0.58 0.907895
86 FYA 0.58 0.906667
87 NB8 0.58 0.897436
88 ME8 0.58 0.841463
89 1ZZ 0.58 0.819277
90 TXD 0.579439 0.884615
91 ADP VO4 0.578947 0.906667
92 VO4 ADP 0.578947 0.906667
93 A4P 0.577982 0.823529
94 LMS 0.576471 0.807229
95 9SN 0.568627 0.85
96 DQV 0.566038 0.932432
97 NAX 0.564815 0.875
98 RAB 0.564103 0.821918
99 ADN 0.564103 0.821918
100 XYA 0.564103 0.821918
101 YAP 0.563107 0.896104
102 FA5 0.563107 0.907895
103 B5Y 0.563107 0.871795
104 B5M 0.563107 0.871795
105 9ZA 0.561224 0.884615
106 9ZD 0.561224 0.884615
107 ADP BMA 0.56 0.894737
108 XAH 0.557692 0.841463
109 GA7 0.556604 0.907895
110 48N 0.555556 0.897436
111 AP0 0.554545 0.873418
112 T5A 0.553571 0.843373
113 4UV 0.552381 0.871795
114 DAL AMP 0.55102 0.881579
115 6V0 0.550459 0.873418
116 NAI 0.550459 0.884615
117 DND 0.550459 0.907895
118 NXX 0.550459 0.907895
119 3AT 0.547368 0.972222
120 LAQ 0.546296 0.819277
121 OMR 0.545455 0.831325
122 TXE 0.545455 0.884615
123 AOC 0.545455 0.8
124 4UU 0.542056 0.871795
125 6AD 0.541667 0.886076
126 7D5 0.541176 0.855263
127 A2R 0.540816 0.958904
128 139 0.539823 0.851852
129 5AS 0.538462 0.761364
130 TAD 0.537037 0.910256
131 4UW 0.536364 0.839506
132 CNA 0.535088 0.907895
133 ATP A A A 0.533333 0.905405
134 DTP 0.53125 0.906667
135 5N5 0.530864 0.797297
136 80F 0.529915 0.843373
137 A3P 0.527473 0.944444
138 YLP 0.527273 0.821429
139 UPA 0.526786 0.884615
140 ADJ 0.526316 0.831325
141 A4D 0.52439 0.797297
142 5CD 0.52439 0.783784
143 A A 0.524272 0.918919
144 DZD 0.521368 0.910256
145 AV2 0.520408 0.893333
146 JB6 0.519231 0.884615
147 TYM 0.517857 0.907895
148 M2T 0.517647 0.716049
149 IOT 0.517544 0.833333
150 F2R 0.517241 0.865854
151 A3D 0.516949 0.894737
152 7DT 0.515789 0.958333
153 MYR AMP 0.514286 0.797619
154 AR6 AR6 0.513761 0.893333
155 7MD 0.513761 0.864198
156 YLC 0.513274 0.841463
157 YLB 0.513274 0.821429
158 COD 0.512821 0.813953
159 NAD 0.512821 0.906667
160 3AM 0.511364 0.90411
161 A2P 0.51087 0.930556
162 PPS 0.510204 0.851852
163 EP4 0.505882 0.734177
164 DAT 0.505263 0.906667
165 G5A 0.505155 0.781609
166 AHZ 0.504505 0.797619
167 DDS 0.5 0.855263
168 YLA 0.5 0.821429
169 NA7 0.5 0.959459
170 DTA 0.5 0.766234
171 SSA 0.5 0.802326
172 3DH 0.5 0.753247
173 7DD 0.5 0.958333
174 AYB 0.495726 0.811765
175 TYR AMP 0.495413 0.871795
176 AMP DBH 0.495413 0.87013
177 MTA 0.494253 0.753247
178 RGT 0.490741 0.933333
179 TSB 0.490196 0.8
180 A5A 0.49 0.788235
181 IMO 0.48913 0.90411
182 NAE 0.487805 0.871795
183 BTX 0.487395 0.843373
184 7MC 0.486957 0.843373
185 LPA AMP 0.486726 0.797619
186 ARG AMP 0.486486 0.831325
187 AVV 0.485437 0.897436
188 V3L 0.484848 0.945205
189 EAD 0.484127 0.851852
190 NAQ 0.483871 0.85
191 S4M 0.483871 0.670455
192 6RE 0.483516 0.7625
193 BT5 0.483333 0.833333
194 2AM 0.483146 0.917808
195 128 0.482456 0.758621
196 54H 0.480392 0.770115
197 VMS 0.480392 0.770115
198 GCP 0.480392 0.922078
199 52H 0.480392 0.761364
200 ZID 0.48 0.894737
201 M24 0.479675 0.829268
202 MAO 0.478723 0.761905
203 AF3 ADP 3PG 0.478261 0.839506
204 ARU 0.47619 0.839506
205 5CA 0.475728 0.802326
206 53H 0.475728 0.761364
207 8X1 0.475728 0.755556
208 HDV 0.475248 0.87013
209 5X8 0.474227 0.766234
210 A3N 0.473118 0.766234
211 J7C 0.473118 0.772152
212 ZAS 0.472527 0.746835
213 GTP 0.470588 0.896104
214 NDE 0.469231 0.907895
215 P1H 0.469231 0.831325
216 N0B 0.468254 0.821429
217 YLY 0.467742 0.811765
218 OVE 0.467391 0.881579
219 P5A 0.46729 0.747253
220 LSS 0.466667 0.764045
221 NSS 0.466667 0.802326
222 DSZ 0.466667 0.802326
223 9K8 0.462963 0.698925
224 G A A A 0.46281 0.85
225 AMP NAD 0.46281 0.881579
226 DSH 0.462366 0.728395
227 A3G 0.462366 0.802632
228 NVA LMS 0.462264 0.755556
229 FB0 0.462121 0.827586
230 6C6 0.46 0.883117
231 TXP 0.458333 0.897436
232 LEU LMS 0.457944 0.755556
233 GDP 0.455446 0.896104
234 FDA 0.455224 0.835294
235 NJP 0.454545 0.921053
236 GSU 0.453704 0.781609
237 KAA 0.453704 0.755556
238 GJV 0.452632 0.753086
239 12D 0.452174 0.767442
240 6FA 0.451852 0.843373
241 NAJ PZO 0.451613 0.82716
242 NDC 0.451128 0.85
243 4TA 0.45082 0.809524
244 0WD 0.45082 0.897436
245 NPW 0.45 0.8875
246 SA8 0.45 0.710843
247 MHZ 0.44898 0.701149
248 NAJ PYZ 0.448819 0.788235
249 N6P 0.448598 0.890411
250 71V 0.447917 0.884615
251 2SA 0.446602 0.933333
252 YSA 0.446429 0.781609
253 NZQ 0.446281 0.910256
254 5AD 0.445783 0.726027
255 FAS 0.445255 0.853659
256 FAD 0.445255 0.853659
257 SFG 0.444444 0.753247
258 PO4 PO4 A A A A PO4 0.444444 0.878378
259 ODP 0.442623 0.886076
260 SMM 0.442308 0.689655
261 J7V 0.44186 0.813953
262 6IA 0.441176 0.839506
263 SAM 0.441176 0.694118
264 7D7 0.440476 0.723684
265 A G 0.439024 0.860759
266 A7D 0.438776 0.779221
267 A3S 0.438776 0.813333
268 7C5 0.438596 0.797468
269 NDP 0.438017 0.897436
270 8PZ 0.4375 0.802326
271 AAT 0.436893 0.710843
272 RFL 0.43662 0.823529
273 A5D 0.435644 0.766234
274 U A G G 0.435484 0.860759
275 SFD 0.434783 0.736842
276 PGS 0.434343 0.860759
277 G2P 0.433962 0.910256
278 GGZ 0.433962 0.804878
279 MGP 0.432692 0.8625
280 62F 0.432624 0.864198
281 FNK 0.432624 0.806818
282 D5M 0.431579 0.88
283 NEC 0.431579 0.727273
284 DA 0.431579 0.88
285 GP3 0.431373 0.897436
286 SAH 0.431373 0.746835
287 SAI 0.431373 0.7375
288 A3T 0.43 0.8
289 6K6 0.429907 0.905405
290 FAY 0.429577 0.864198
291 U A 0.428571 0.884615
292 6G0 0.428571 0.8625
293 S7M 0.428571 0.694118
294 XNP 0.427419 0.851852
295 AAM 0.427083 0.944444
296 Y3J 0.425287 0.706667
297 AMZ 0.423913 0.891892
298 C2R 0.423913 0.88
299 EEM 0.423077 0.694118
300 A U 0.421488 0.848101
301 Z5A 0.419847 0.761364
302 4YB 0.418803 0.764045
303 A A A 0.418182 0.906667
304 GEK 0.416667 0.740741
305 NA0 0.416667 0.907895
306 WSA 0.416667 0.790698
307 AIR 0.41573 0.876712
308 NIA 0.414894 0.802469
309 ETB 0.414062 0.835294
310 DCA 0.414062 0.825581
311 GAV 0.412844 0.8625
312 NAP 0.412214 0.92
313 PUA 0.410853 0.8625
314 APU 0.409836 0.871795
315 GNH 0.409524 0.884615
316 TAP 0.409091 0.884615
317 62X 0.409091 0.670455
318 ZDA 0.407767 0.842105
319 IDP 0.407767 0.894737
320 0T1 0.407692 0.825581
321 COA 0.407692 0.825581
322 9GM 0.407407 0.873418
323 GSP 0.407407 0.851852
324 GNP 0.407407 0.873418
325 TM1 0.40708 0.755814
326 101 0.40625 0.855263
327 A6D 0.405405 0.705882
328 K15 0.405405 0.686047
329 9JJ 0.405405 0.841463
330 V1N 0.405172 0.893333
331 649 0.404959 0.747253
332 F2N 0.403974 0.816092
333 FCX 0.402985 0.797753
334 7RP 0.402062 0.902778
335 MGO 0.401869 0.839506
336 8Q2 0.401639 0.775281
337 FA9 0.401316 0.865854
338 0UM 0.4 0.702381
339 P5F 0.4 0.825581
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LLB; Ligand: 6YZ; Similar sites found with APoc: 355
This union binding pocket(no: 1) in the query (biounit: 5llb.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1HTW ADP None
2 1YZG GDP None
3 1G16 GDP None
4 5H4S RAM None
5 4YLG GDP None
6 1GXU 2HP None
7 1P72 ADP 1.14068
8 3AQ4 GDP 1.63043
9 3EWA ANP 1.90114
10 2GDJ ANP 1.90114
11 4PX9 ADP 1.90114
12 5ZBR ANP 1.90114
13 5H7K GDP 1.90114
14 3CNL GNP 1.9084
15 2QZ4 ADP 1.9084
16 1G6H ADP 1.94553
17 2ZE7 DST 1.97628
18 2ZE7 AMP 1.97628
19 4WOP CTP 2.22222
20 1SQ5 ADP 2.23048
21 5G41 AP5 2.24215
22 1XP8 AGS 2.28137
23 5LB3 ADP 2.28137
24 5YT0 GDP 2.28137
25 5Y6N ADP 2.28137
26 2IS6 ADP 2.28137
27 4WEI GLC GAL 2.28137
28 1B0U ATP 2.29008
29 2GCO GNP 2.48756
30 4BFW ZVW 2.60223
31 1A4R GNH 2.6178
32 1GOJ ADP 2.6616
33 4Q1A 2XZ 2.6616
34 4Q1A UDP 2.6616
35 1V8K ANP 2.6616
36 3P4X ADP 2.6616
37 3ZFD ANP 2.6616
38 4QOS ADP 2.6616
39 2XAU ADP 2.6616
40 4UXH T5A 2.71739
41 2J0V GDP 2.83019
42 1UPT GTP 2.92398
43 3W5J GDP 2.94118
44 1GRN GDP 2.95567
45 2W58 ADP 2.9703
46 4KVA GTP 2.97398
47 5GVR LMR 2.99145
48 2ORV 4TA 2.99145
49 1R4A GNP 3.0303
50 2W83 GTP 3.0303
51 2VVG ADP 3.04183
52 5ZXD ATP 3.04183
53 3U6B GDP 3.04183
54 1SKQ GDP 3.04183
55 4B47 GDP 3.04183
56 5JBQ GDP 3.04183
57 4G5G GDP 3.04183
58 1D8T GDP 3.04183
59 3U6K GDP 3.04183
60 4ZNL BEF ADP 3.04183
61 5XDR ADP 3.04183
62 1R6B ADP 3.04183
63 2BVN GNP 3.04183
64 5VHC BEF ADP 3.04183
65 1Z83 AP5 3.06122
66 3N5C GDP 3.08642
67 3H86 AP5 3.125
68 5KSP GDP 3.15789
69 2X77 GDP 3.1746
70 5BQ5 ADP BEF 3.1746
71 5IRC GDP 3.22581
72 3LXR GDP 3.24324
73 3B5J 12D 3.29218
74 4E03 ADP 3.39806
75 2JAQ DCP 3.41463
76 2XT3 ADP 3.42205
77 4JLV ADP 3.42205
78 5JCP GDP ALF 3.42205
79 6AU6 GDP 3.42205
80 2HT6 GDP 3.44828
81 3UIE ANP 3.5
82 1W4R TTP 3.58974
83 2ZX2 RAM 3.58974
84 3Q72 GNP 3.61446
85 2CJW GDP 3.64583
86 1VHT BA3 3.66972
87 4U00 ADP 3.68852
88 5KUT GDP 3.7037
89 2O66 FLC 3.7037
90 1RRC ADP 3.80228
91 3LRE ADP 3.80228
92 3COB ADP 3.80228
93 1OXV ANP 3.80228
94 2HCJ GDP 3.80228
95 4D0N GDP 3.80228
96 1R0X ATP 3.80228
97 1VKJ A3P 3.80228
98 4R43 GDP 3.80228
99 3RC1 NAP 3.80228
100 1Y63 ADP 3.80435
101 1FZQ GDP 3.8674
102 1RYH GNP 3.94089
103 1UJ2 ADP 3.96825
104 1UJ2 C5P 3.96825
105 2D2F ADP 4
106 5O74 GDP 4.06091
107 3GJ7 GDP 4.0724
108 3GJ4 GDP 4.0724
109 3GJ3 GDP 4.0724
110 3GJ0 GDP 4.0724
111 3GJ5 GDP 4.0724
112 3GJ8 GDP 4.0724
113 3Q85 GNP 4.14201
114 1DS6 GDP 4.16667
115 3CH5 GDP 4.16667
116 5FG3 GDP 4.18251
117 5W7Q GDP 4.18251
118 5W76 GDP 4.18251
119 3BFV ADP 4.18251
120 5Z69 AGS 4.18251
121 2DPY ADP 4.18251
122 3CV2 COA 4.18251
123 1MH1 GNP 4.30108
124 4KAX GTP 4.34783
125 4P3Y GDP 4.3956
126 6B8B ADP 4.41767
127 1DAK DPU 4.46429
128 1DAK ADP 4.46429
129 1S8F GDP 4.51977
130 4YMU ATP 4.54545
131 4BQS ADP 4.54545
132 4BQS K2Q 4.54545
133 2G77 AF3 4.54545
134 2AWN ADP 4.56274
135 3TK1 GDP 4.56274
136 3WYA GDP 4.56274
137 4IHQ ADP 4.56274
138 4A4Z ANP 4.56274
139 1K6M AGS 4.56274
140 5HCN GCP 4.5977
141 4NU0 AP5 4.60829
142 1SVI GDP 4.61538
143 1Z06 GNP 4.7619
144 5G3Y ADP 4.86726
145 1RE0 GDP 4.87805
146 1S9D GDP 4.87805
147 1T5C ADP 4.94297
148 3NHB ADP 4.94297
149 5M04 GDP 4.94297
150 5ULJ 0WD 4.94297
151 1U0J ADP 4.94297
152 1G7S GDP 4.94297
153 3PCR GTP 4.94297
154 5X40 ACP 4.94297
155 4PC3 GDP 4.94297
156 1TQ4 GDP 4.94297
157 2CBZ ATP 5.06329
158 5CK5 GDP 5.06329
159 4CVN ADP 5.10949
160 2NGR GDP 5.12821
161 4X8O AP5 5.14019
162 1D2E GDP 5.20446
163 1XX6 ADP 5.2356
164 4DID GDP 5.26316
165 4GOJ GNP 5.29101
166 5KSZ GCP 5.32319
167 1XMV ADP 5.32319
168 2ZFI ADP 5.32319
169 4LYA ATP 5.32319
170 5HR5 ADP 5.32319
171 2NCD ADP 5.32319
172 5TB5 GDP 5.40541
173 5TAR GDP 5.40541
174 2QQ0 ADP 5.43478
175 2QQ0 TMP 5.43478
176 2QQ0 ANP 5.43478
177 2QQ0 THM 5.43478
178 5U32 GDP 5.50847
179 2PL3 ADP 5.50847
180 3TMK T5A 5.55556
181 4DKX GDP 5.55556
182 1D5C GDP 5.55556
183 3T1O GDP 5.55556
184 2PZE ATP 5.67686
185 1BG2 ADP 5.70342
186 4ZG4 VO4 ADP 5.70342
187 4R98 GNH 5.70342
188 1RYO OXL 5.70342
189 3DZD ADP 5.70342
190 5IRN ADP 5.70342
191 3DKP ADP 5.71429
192 5UIV ADP 5.72687
193 2A5J GDP 5.75916
194 3A4M ADP 5.76923
195 1JI0 ATP 5.83333
196 4HI0 GDP 5.90551
197 2QG6 NMN 6.03015
198 1MR3 G3D 6.07735
199 5TSH ADP 6.08365
200 5TSH ANP 6.08365
201 6A20 ADP 6.08365
202 2WIC GNP 6.08365
203 1E2K TMC 6.08365
204 3IO3 ADP 6.08365
205 1Z0F GDP 6.14525
206 5MVR ADP 6.17284
207 2RGX AP5 6.31068
208 3A1S GDP 6.3197
209 4NE2 SH2 6.46388
210 4NE2 ADP 6.46388
211 2BIF SIN 6.46388
212 2OG2 MLI 6.46388
213 2BIF ANP 6.46388
214 3B9Q MLI 6.46388
215 1OS1 PYR 6.46388
216 5Z2M GTP 6.52174
217 5BN3 ADP 6.69145
218 1OIV GDP 6.80628
219 4WZ6 ATP 6.84411
220 4AG5 ADP 6.84411
221 2JLR ANP 6.84411
222 2A5F GTP 6.85714
223 1YRB GDP 6.87023
224 1Z0A GDP 6.89655
225 4MKF AP5 6.91244
226 1ZJ6 G3D 6.95187
227 4TTQ ATP 6.97674
228 4LPS GDP 7.02479
229 1VG1 GDP 7.02703
230 1VG9 GDP 7.02703
231 4KFU ACP 7.07547
232 4QRH 0O2 7.14286
233 3PQC GDP 7.17949
234 1QF9 ALF 7.2165
235 1QF9 C5P 7.2165
236 1QF9 ADP 7.2165
237 1ZIN AP5 7.37327
238 3FB4 AP5 7.40741
239 2KIN ADP 7.56302
240 1YQT ADP 7.60456
241 5YV5 ADP 7.60456
242 3TBK ANP 7.60456
243 1G6O ADP 7.60456
244 4IEE AGS 7.60456
245 1FP6 ADP 7.60456
246 4MIB 28M 7.60456
247 1JJV ATP 7.76699
248 1J2J GTP 7.83133
249 1O3Y GTP 7.83133
250 2J59 GTP 7.83133
251 2V54 TYD 7.84314
252 4YDS ATP 7.89474
253 3H4S ADP 7.98479
254 4FRZ ADP 7.98479
255 1KK1 GNP 7.98479
256 1MKY GDP 7.98479
257 1W0J ADP 7.98479
258 2V7Q ADP 8
259 2V7Q ATP 8
260 2CK3 ANP 8
261 3UXM 0DN 8.05687
262 1AKY AP5 8.18182
263 1OE0 TTP 8.26087
264 2WMO GTP 8.36502
265 2WJG GDP 8.51064
266 4J0Q GDP 8.55019
267 4DCT GDP 8.55019
268 4R2I ANP 8.57143
269 5BXQ GDP 8.66142
270 3QXC ATP 8.67769
271 5LTJ ADP 8.74525
272 5LTJ BEF 8.74525
273 5WC2 ADP 8.74525
274 2B8T THM 8.96861
275 4ZI2 GNP 9.02256
276 5ZB0 TYD 9.09091
277 5ZB0 ADP 9.09091
278 1NN5 2DT 9.30233
279 1NN5 ANP 9.30233
280 5AK0 8V1 9.5057
281 2RCN GDP 9.5057
282 5W75 GDP 9.5057
283 1DAR GDP 9.88593
284 5GOE GDP 9.88593
285 4PFO ADP 9.88593
286 2VB6 ADP BEF 9.88593
287 2YOH WMJ 10
288 4NON GDP 10
289 1S3G AP5 10.1382
290 2CE7 ADP 10.6464
291 4WZA ACP 10.6464
292 4WZA ADP 10.6464
293 6G14 G4P 10.6464
294 2CDN ADP 10.9453
295 3MD0 GDP 11.0266
296 6BSX GDP 11.236
297 5IFS ADP 11.3924
298 3SFV GDP 11.6022
299 1LVG ADP 11.6162
300 4QM7 GTP 11.6959
301 2FSH ANP 12.1673
302 2IXE ATP 12.1673
303 1JJ7 ADP 12.3077
304 2HF9 GSP 12.3894
305 1PUJ GNP 12.5475
306 1W7J ADP BEF 12.5828
307 1LVK MNT BEF 12.9278
308 4TMK T5A 13.1455
309 3T5G GDP 13.2597
310 1F6B GDP 13.6364
311 4PPF FLC 13.6882
312 3DC4 ADP 13.6882
313 2ZR9 DTP 13.6882
314 4LC1 GDP 13.6882
315 3IIJ ADP 13.8889
316 3B7G ANP 13.913
317 1TU3 GNP 13.9241
318 3QF7 ANP 14
319 3E70 GDP 14.0684
320 1B7T ADP 14.1026
321 1KK8 BEF ADP 14.3885
322 1M7G AV2 14.6919
323 1M7G ADP 14.6919
324 1M7G ADX 14.6919
325 1UKZ ADP 14.7783
326 2Y65 ADP 15
327 5XKT GNP 15
328 2WJH GDP 15.0602
329 2WJH FLC 15.0602
330 5N69 ADP 15.9696
331 1I4D GDP 16.5179
332 5LXT 7AK 17.4825
333 3DOE GTP 18.2292
334 2QN6 GDP 18.2796
335 3BOS CDP 19.0114
336 3ZIA ATP 19.0476
337 3ZIA ADP 19.0476
338 5O2T GSP 19.5266
339 1X6V ADP 20.1521
340 5L3S G 20.4461
341 5UPK GNP 20.8333
342 5L3V GDP 20.9125
343 4K81 GTP 21.0526
344 1CLU DBG 21.6867
345 3WY9 GDP 21.875
346 1SVK ALF GDP 22.4335
347 5KDO GDP 22.4335
348 1GP2 GDP 22.4335
349 3KTA AP5 22.5275
350 2GKS ADP 23.5741
351 4MKG AP5 24.424
352 2OFW ADX 25.4808
353 2PEZ GGZ 29.6089
354 2PEZ DAT 29.6089
355 6C90 ADP 40.3846
Pocket No.: 2; Query (leader) PDB : 5LLB; Ligand: 6YZ; Similar sites found with APoc: 20
This union binding pocket(no: 2) in the query (biounit: 5llb.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 2WCU FUC None
2 5AOG IAC 1.52091
3 4ZDJ UTP 1.90114
4 2P3I MNA 2.48447
5 2FAH GDP 3.04183
6 1QXA GLY GLY GLY 3.40426
7 1XKV ATP 3.80228
8 1OW3 GDP 4.95868
9 5ECP MET 6.08365
10 4HSE ADP 6.84411
11 5M7P ADP 7.60456
12 1Z6T ADP 8.36502
13 1F9V ADP 10.2662
14 5FTB ANP 11.0266
15 5FHD ADP ALF 11.0266
16 3W5N RAM 13.308
17 6BVJ EAS 21.5569
18 6BVL EBY 21.5569
19 6BVI EC4 21.5569
20 1OYY AGS 23.1939
Pocket No.: 3; Query (leader) PDB : 5LLB; Ligand: 6YZ; Similar sites found with APoc: 12
This union binding pocket(no: 3) in the query (biounit: 5llb.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 4YJ1 ADP 5.32319
2 3FWY ADP 5.41401
3 1GPM CIT 5.70342
4 5HPY GDP 6.03448
5 4OHU NAD 8.36502
6 4OHU 2TK 8.36502
7 1LDM OXM 8.36502
8 5KOH HCA 8.74525
9 5HV7 RBL 9.88593
10 1KJ1 MAN 11.0092
11 3AB4 THR 11.7978
12 2D7D ADP 12.5
Pocket No.: 4; Query (leader) PDB : 5LLB; Ligand: 6YZ; Similar sites found with APoc: 6
This union binding pocket(no: 4) in the query (biounit: 5llb.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1ONI BEZ None
2 3HDY FDA 1.90114
3 3HDY GDU 1.90114
4 4G86 BNT 3.04183
5 1PU7 39A 9.63303
6 5Y02 MXN 14.9533
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