Receptor
PDB id Resolution Class Description Source Keywords
5LI1 2 Å EC: 2.7.11.13 STRUCTURE OF A PAR3-INHIBITORY PEPTIDE BOUND TO PKCIOTA CORE DOMAIN HOMO SAPIENS APKC POLARITY COMPLEX TRANSFERASE
Ref.: APKC INHIBITION BY PAR3 CR3 FLANKING REGIONS CONTRO SUBSTRATE ACCESS AND UNDERPINS APICAL-JUNCTIONAL POLARIZATION. DEV.CELL V. 38 384 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:604;
A:605;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP A:601;
Valid;
Atoms found LESS than expected: % Diff = 0.129;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
GOL A:602;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
K A:603;
Part of Protein;
none;
submit data
39.098 K [K+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LI1 2 Å EC: 2.7.11.13 STRUCTURE OF A PAR3-INHIBITORY PEPTIDE BOUND TO PKCIOTA CORE DOMAIN HOMO SAPIENS APKC POLARITY COMPLEX TRANSFERASE
Ref.: APKC INHIBITION BY PAR3 CR3 FLANKING REGIONS CONTRO SUBSTRATE ACCESS AND UNDERPINS APICAL-JUNCTIONAL POLARIZATION. DEV.CELL V. 38 384 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5LI1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5LI1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4DC2 - ADE C5 H5 N5 c1[nH]c2c(....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5LI1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4DC2 - ADE C5 H5 N5 c1[nH]c2c(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LI1; Ligand: ANP; Similar sites found: 393
This union binding pocket(no: 1) in the query (biounit: 5li1.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5N1X 8HH 0.002845 0.42681 None
2 1RZX ACE VAL LYS GLU SER LEU VAL 0.01595 0.41619 None
3 5KJW 53C 0.01709 0.41956 1.41243
4 1M2W MTL 0.02111 0.40908 1.41243
5 5W2I ADP 0.0003214 0.43975 1.55642
6 5W2I I3P 0.0003214 0.43975 1.55642
7 2PYW ADP 0.0000006427 0.57231 1.69492
8 3WVR AMP 0.0001465 0.49271 1.69492
9 3ETH ATP 0.002908 0.41331 1.69492
10 4IP7 FLC 0.02195 0.40683 1.69492
11 3V4S ATP 0.005955 0.40031 1.69492
12 4YGF AZM 0.007353 0.40287 1.7094
13 1JJE BYS 0.007176 0.40005 1.8018
14 1ZP9 ATP 0.0000001773 0.62812 1.93798
15 3RE4 TO1 0.000001854 0.59727 1.93798
16 1ZTH ADP 0.0000001025 0.53391 1.93798
17 4RDL FUC GAL NDG FUC 0.02467 0.4059 1.94805
18 4OUJ LBT 0.005518 0.4321 1.9544
19 4U98 ACP 0.000478 0.46383 1.9774
20 1F52 ADP 0.004705 0.42695 1.9774
21 4R78 AMP 0.000001375 0.61279 2.25989
22 3X01 AMP 0.00028 0.50682 2.25989
23 2CFM AMP 0.001978 0.44979 2.25989
24 3LJU IP9 0.01853 0.41489 2.25989
25 3HQP OXL 0.02118 0.40848 2.25989
26 3W0O HY0 0.0001721 0.42156 2.29226
27 3W0O ADP 0.0001721 0.42156 2.29226
28 4ZGP ADP 0.01209 0.40005 2.38908
29 5USZ SKE 0.0000001679 0.54077 2.42215
30 2GCG DGY 0.02258 0.40392 2.42424
31 4LH7 1X8 0.001449 0.46431 2.47678
32 5MW8 ATP 0.000000061 0.61126 2.54237
33 1VRP IOM 0.01351 0.40246 2.54237
34 1MJT ITU 0.01383 0.40592 2.59366
35 4ZS4 ATP 0.0000001913 0.60209 2.60586
36 5AEW BNL 0.007666 0.42108 2.65957
37 5TH5 MET 0.03053 0.40028 2.6616
38 3UDZ ADP 0.00000001478 0.61404 2.82486
39 4PU5 ANP 0.0003697 0.44513 2.82486
40 1EHI ADP 0.002176 0.42588 2.82486
41 5FJN BE2 0.02323 0.40121 2.82486
42 3PDT ADP 0.0000005051 0.60702 2.90909
43 1I7L ATP 0.0003362 0.44038 2.91262
44 5K2M ADP 0.0003333 0.45652 2.9304
45 1CKM GTP 0.0069 0.42789 3.0303
46 4OCJ NDG 0.000002775 0.5676 3.10734
47 5MRH Q9Z 0.0008086 0.47446 3.10734
48 2VQD AP2 0.0002835 0.45981 3.10734
49 4OYA 1VE 0.005216 0.44187 3.10734
50 2Z49 AMG 0.01701 0.41573 3.10734
51 1IA9 ANP 0.000001253 0.56663 3.21429
52 3TDV GDP 0.00000000875 0.6693 3.26797
53 4OCV ANP 0.00000651 0.53555 3.38983
54 2YRX AMP 0.002599 0.45636 3.38983
55 3DNT ATP 0.0004066 0.43815 3.38983
56 1PK8 ATP 0.0003376 0.43432 3.38983
57 5TT6 ATP 0.001831 0.42169 3.38983
58 3ORQ ADP 0.002458 0.41989 3.38983
59 4DFU QUE 0.01067 0.42301 3.41615
60 5C4L 4XR 0.00002651 0.5145 3.42679
61 5C4L SIS 0.00007546 0.49478 3.42679
62 5A5W GUO 0.006606 0.42069 3.55731
63 1Q8Q MAN MMA 0.0301 0.40275 3.57143
64 2XG5 EC2 0.01012 0.41976 3.66972
65 2XG5 EC5 0.01012 0.41976 3.66972
66 3PUR 2HG 0.0101 0.42605 3.67232
67 2YW2 ATP 0.00309 0.41565 3.67232
68 1SU2 ATP 0.00381 0.419 3.77358
69 3TM0 ANP 0.0001636 0.41436 3.80228
70 3TM0 B31 0.0001772 0.40882 3.80228
71 4CYI ATP 0.000003737 0.52663 3.9548
72 1XVB BHL BHL 0.01398 0.41167 4.11765
73 2GQS ADP 0.00003581 0.51489 4.21941
74 2GQR ADP 0.00004684 0.46265 4.21941
75 2GQS C2R 0.003595 0.42816 4.21941
76 2PUL ACP 0.000004755 0.55468 4.23729
77 2IO8 ADP 0.0003203 0.44108 4.23729
78 1M0W ANP 0.001999 0.40132 4.23729
79 2Z77 NCA 0.01496 0.41545 4.31655
80 1CBK ROI 0.007132 0.43414 4.375
81 2QX0 PH2 0.001275 0.47742 4.40252
82 4RYV ZEA 0.01669 0.40453 4.51613
83 2G50 PYR 0.01135 0.42492 4.51977
84 4OKD GLC GLC GLC 0.02859 0.4034 4.51977
85 2VK2 GZL 0.0168 0.4129 4.57516
86 5T96 79J 0.02321 0.40475 4.67836
87 2IF8 ADP 0.00008096 0.53184 4.80226
88 4Z4P SAH 0.01156 0.40093 4.81928
89 5CPR 539 0.01025 0.41927 4.85075
90 3K5I ADP 0.00573 0.40422 5.08475
91 3LQV ADE 0.01398 0.4039 5.21739
92 1Q1Y BB2 0.007809 0.41248 5.2356
93 2BKK ADP 0.00006836 0.51434 5.32544
94 4B1L FRU 0.02041 0.40822 5.45455
95 4JGP PYR 0.01294 0.4206 5.52995
96 3AKK ADP 0.0001289 0.47922 5.53846
97 3AB4 THR 0.01873 0.40609 5.61798
98 2DTJ THR 0.01948 0.40123 5.61798
99 5D9G GLU ASN LEU TYR PHE GLN 0.01783 0.40717 5.69106
100 4LO2 GAL BGC 0.007424 0.43221 6.12245
101 5FS0 5JC 0.005638 0.43228 6.16114
102 3I0O ADP 0.0001427 0.50541 6.19469
103 4AZW ATP 0.0001542 0.46162 6.21469
104 2SFP PPI 0.01204 0.40013 6.21469
105 5C1P ADP 0.0006796 0.46693 6.53595
106 1TZD ADP 0.00004621 0.5475 6.54545
107 1I06 TZL 0.007847 0.42989 6.66667
108 1OPB RET 0.008571 0.40687 6.71642
109 3VPC ADP 0.0001219 0.47075 6.73759
110 4CC6 L5Y 0.008963 0.42219 6.91824
111 4FE2 ADP 0.0003725 0.47935 7.05882
112 4FE2 AIR 0.01329 0.40939 7.05882
113 4LRJ ANP 0.0000000005588 0.73299 7.10059
114 4IX4 ADP 0.000003618 0.52774 7.14286
115 1W2D ADP 0.0002336 0.49499 7.16981
116 1OBD ATP 0.00006668 0.44331 7.18954
117 2NGR AF3 0.0119 0.42058 7.26496
118 1YRO UDP 0.0243 0.40689 7.31707
119 3MA0 XYP 0.01667 0.41302 7.34824
120 2BOS GLA GAL 0.01572 0.4041 7.35294
121 2BOS GLA GAL GLC 0.01816 0.40205 7.35294
122 1QY1 PRZ 0.002044 0.4197 7.47126
123 2VPQ ANP 0.0001923 0.46459 7.62712
124 5KBE IPH 0.007989 0.42949 7.86026
125 2QK4 ATP 0.0007275 0.40187 7.9096
126 3RET PYR 0.009722 0.40804 7.92079
127 3RET SAL 0.009722 0.40804 7.92079
128 5TDF ADP 0.001044 0.42806 8.47458
129 5CQG 55C 0.0319 0.40008 8.47458
130 3VPB ADP 0.00001317 0.48741 8.92857
131 4OUC 5ID 0.000000001111 0.73039 8.96359
132 2WSB NAD 0.01878 0.40115 9.05512
133 4AZT LY2 0.0009139 0.46614 9.31459
134 5IQD GNP 0.0002011 0.48363 9.5082
135 5IQD RIO 0.0002156 0.48363 9.5082
136 4K55 H6P 0.02829 0.40208 9.67742
137 4RT1 C2E 0.01094 0.40203 9.82143
138 4XYM A12 0.0005917 0.45047 10
139 5L2J 6UL 0.01975 0.41505 10
140 5L2J 70E 0.02093 0.41505 10
141 4XBT 3ZQ 0.01033 0.41067 10.3226
142 1UNQ 4IP 0.02013 0.41093 10.4
143 3HAV ATP 0.001072 0.4755 11.7057
144 5CKW ANP 0.000001485 0.60197 12.4294
145 3Q60 ATP 0.0000001192 0.62731 12.9944
146 4G17 0VN 0.000001544 0.50716 13.6364
147 1UYY BGC BGC 0.01329 0.41809 13.7405
148 3VOT ADP 0.0004632 0.48051 13.8418
149 3VSV XYS 0.01815 0.41403 14.1243
150 5DMZ ADP 0.000000000001096 0.84248 14.4068
151 4BKJ STI 0.001625 0.40747 14.6032
152 4GYI ADP 0.000001278 0.59648 15
153 2PZI AXX 0.000002726 0.58084 15.2542
154 4O1P ANP 0.00000002737 0.59639 15.5367
155 3VHE 42Q 0.0000005422 0.50242 15.8192
156 1VJY 460 0.000000002405 0.56242 16.1716
157 4BTK DTQ 0.000002363 0.52344 16.3205
158 4XH0 ADP 0.0000002878 0.66477 16.6667
159 2HJ9 AI2 0.02606 0.40383 17.1946
160 4IJP 1EH 0.00000001639 0.62322 17.2316
161 4NFN 2KC 0.000007013 0.54702 17.7994
162 2QLU ADE 0.0000002821 0.67554 18.1529
163 4Q5H ANP 0.0000001717 0.61193 18.3908
164 5KO1 6UY 0.000000946 0.5865 19.0813
165 4Y0X ADP 0.0000002176 0.62399 19.2
166 1DZK PRZ 0.003717 0.42338 19.7452
167 4OAV ACP 0.00000001481 0.66841 19.774
168 4UWH JXM 0.001058 0.45284 20
169 2CSN CKI 0.0006738 0.47902 20.202
170 4I94 ANP 0.00000001396 0.59446 21.6667
171 1CM8 ANP 0.000000254 0.54948 22.8814
172 3E7O 35F 0.000006562 0.45115 23.1638
173 4XMF HSM 0.00005934 0.55789 23.3696
174 4WW7 AMP 0.000006119 0.5249 24.0642
175 3PP0 03Q 0.00000008691 0.55659 24.2604
176 4YZC STU 0.000000001696 0.70819 24.2938
177 4F9C 0SX 0.00000000003041 0.69416 24.8588
178 5UIU 8CG 0.000000003093 0.68266 25
179 1TQP ATP 0.000003118 0.51864 25
180 4KBA 1QM 0.00002224 0.46494 25
181 5W4W 9WG 0.00001028 0.45845 25
182 3TII ANP 0.001722 0.45272 25
183 1XDN ATP 0.013 0.40215 25
184 5LXT ACP 0.004252 0.40176 25
185 4FL3 ANP 0.0000000008347 0.686 25.1412
186 1U5R ATP 0.0000000009575 0.71195 25.2874
187 2WU6 DKI 0.00000001581 0.62006 26.2712
188 3H9R TAK 0.000001067 0.61829 26.3636
189 5AWM ANP 0.000000011 0.70572 26.5537
190 4XV1 904 0.0000004786 0.59417 26.7123
191 3KMW ATP 0.0001851 0.48253 26.9373
192 2B9J ADP 0.0000000003921 0.73997 27.1955
193 2B9I ADP 0.0000000007094 0.71773 27.1955
194 2B9H ADP 0.000000001332 0.65731 27.1955
195 2B9F ADP 0.0000000007788 0.65558 27.4788
196 4IDT T28 0.0000000005241 0.73426 27.6836
197 3LXK MI1 0.00000000268 0.60447 27.8287
198 1Y57 MPZ 0.000003536 0.52518 27.9661
199 3C1X CKK 0.0001566 0.46621 27.9661
200 4CQE CQE 0.000004356 0.53106 28.0576
201 5C03 AGS 0.000002272 0.56215 28.0702
202 4CRL C1I 0.0000009697 0.47958 28.2486
203 5BVE 4VG 0.0000000349 0.40819 28.2486
204 5X8I SQZ 0.0000000001585 0.74662 28.3237
205 4QTB 38Z 0.00000002701 0.63958 28.5311
206 4NM5 ADP 0.00000004898 0.59963 28.5311
207 2JLD AG1 0.000000006894 0.54388 28.5311
208 3PTG 932 0.00000003414 0.5368 28.5311
209 4UX9 ANP 0.00000000003573 0.7533 28.8136
210 4IZY 1J2 0.00000005412 0.61802 28.8136
211 3TTI KBI 0.000000005775 0.59063 28.8136
212 3ZRM ZRM 0.0000001286 0.56934 28.8136
213 4WHZ 3NL 0.00000382 0.40331 28.8136
214 5T8O 76Z 0.0000000401 0.62356 28.9398
215 4OH4 ANP 0.00000005235 0.63482 29.1291
216 3F7Z 34O 0.000000006241 0.61968 29.1429
217 5LPZ ADP 0.00000009736 0.62286 29.2169
218 4N70 2HX 0.00000002487 0.45069 29.2683
219 4YLL 4E3 0.000000009032 0.64604 29.3785
220 3GC8 B45 0.000003371 0.5357 29.3785
221 5EFQ ADP 0.000000009168 0.6684 29.3948
222 3PLS ANP 0.000000008627 0.67906 29.5302
223 5HES 032 0.00000053 0.56918 29.6417
224 4ASE AV9 0.000003918 0.48607 29.745
225 4NST ADP 0.00000001241 0.66256 29.9145
226 3OFM 4B0 0.00000002812 0.56382 30
227 5DZT AMP 0.001364 0.47029 30
228 5VZ0 ADP 0.0001091 0.45227 30
229 5NKB 8ZT 0.000004505 0.4235 30.0654
230 4Y85 499 0.0000005541 0.59704 30.1205
231 5HVJ ANP 0.00000001444 0.73693 30.1587
232 5MY8 RXZ 0.0000001747 0.55733 30.226
233 4WOV 3SM 0.00001279 0.54894 30.2839
234 5EOB 5QQ 0.0000002507 0.63505 30.4075
235 5HX8 66P 0.00000002783 0.57712 30.4636
236 2YAB AMP 0.000000000508 0.71398 30.5085
237 3CY2 MB9 0.00000001346 0.62224 30.5732
238 4M69 ANP 0.000000009429 0.6503 30.6709
239 2H8H H8H 0.00000002077 0.65264 30.791
240 3SXF BK5 0.0000000348 0.51247 30.791
241 5JKG 6LF 0.00000303 0.5659 30.8682
242 3KRL KRL 0.000002164 0.54372 31.0448
243 3HZT J60 0.0000000326 0.68274 31.0734
244 5DBX ANP 0.0000000007964 0.61288 31.0976
245 2PVN P63 0.0000000001671 0.62966 31.25
246 3UIM ANP 0.00000006456 0.63078 31.2883
247 3DLS ADP 0.000000002337 0.61131 31.3433
248 3IGO ANP 0.000000001528 0.67506 31.3559
249 3E8N VRA 0.00000003837 0.46757 31.3783
250 3E8N ATP 0.00000003837 0.46757 31.3783
251 3PE2 E1B 0.0000001598 0.63423 31.454
252 3ALN ANP 0.00000001516 0.64153 31.4985
253 2V7O DRN 0.000000002583 0.57582 31.5476
254 3GQI ACP 0.000000001409 0.7045 31.5951
255 5LXC 7AA 0.00000000002542 0.68251 31.6384
256 3BU5 ATP 0.00000003573 0.59102 31.6993
257 2PVF ACP 0.0000000009237 0.72309 31.7365
258 3M2W L8I 0.00000000006592 0.65351 31.7726
259 2XVD AS6 0.000005442 0.48214 31.7881
260 4E93 GUI 0.0000001126 0.51452 31.9209
261 3VRY B43 0.000002672 0.51106 31.9209
262 4K33 ACP 0.0000000006682 0.66911 32
263 3EKK GS2 0.0000003592 0.47315 32.2476
264 5HCY 60D 0.0000008538 0.43894 32.3263
265 2X2M X2M 0.000000006986 0.64754 32.4841
266 5DEY 59T 0.00001071 0.42385 32.6599
267 3GNI ATP 0.00000001309 0.64424 32.7684
268 4P5Z Q7M 0.00001263 0.42744 32.7684
269 5LPB ADP 0.00000005614 0.67124 32.7703
270 4AT3 LTI 0.00001373 0.45932 32.7759
271 4G31 0WH 0.00002478 0.42829 32.7759
272 2OO8 RAJ 0.002913 0.41328 32.8076
273 4JR7 GNP 0.00000000004801 0.76963 32.8877
274 2Y6O 1N1 0.00001911 0.50429 32.9897
275 5CEO 50D 0.000001957 0.52457 33
276 1K3A ACP 0.0000004146 0.61971 33.1104
277 5UR1 YY9 0.0000016 0.58449 33.119
278 1UNH IXM 0.000000003996 0.71552 33.2192
279 3O0G 3O0 0.000000003781 0.61465 33.2192
280 4AG8 AXI 0.0000006745 0.46541 33.2278
281 1JPA ANP 0.0000005237 0.63078 33.3333
282 5MJA 7O3 0.00000294 0.49963 33.4426
283 4AU8 Z3R 0.00000009384 0.66037 33.4459
284 3RI1 3RH 0.0000002164 0.59599 33.5463
285 4QMN DB8 0.0000003985 0.47718 33.5484
286 1OPK P16 0.000006262 0.45966 33.6158
287 5DRB 5FJ 0.0000006157 0.42801 33.677
288 2A19 ANP 0.00000003692 0.6801 34.1549
289 4CLI 5P8 0.00000244 0.57768 34.2508
290 4AUA 4AU 0.000000102 0.63039 34.5277
291 1V0O INR 0.0000000005896 0.71117 34.7222
292 2RIO ADP 0.00000000006974 0.68622 34.7458
293 5HQ0 LZ9 0.0000000005764 0.70193 34.7682
294 4EUU BX7 0.00000001448 0.58722 34.7962
295 5I35 ANP 0.000004248 0.5569 35
296 2AQX ATP 0.0006575 0.44024 35
297 4J1Q NDP 0.00871 0.40257 35
298 2OFV 242 0.000006435 0.4439 35.0181
299 5BYZ 4WE 0.0000003668 0.50337 35.0575
300 1U59 STU 0.000000001815 0.69962 35.1916
301 1Q8Y ADP 0.00000000003332 0.73263 35.3107
302 1Q8Y ADE 0.0000000482 0.53611 35.3107
303 4Y8D 49J 0.0000001726 0.61182 35.5882
304 4H3Q ANP 0.0000000006568 0.69377 35.5932
305 1BYG STU 0.0000000001786 0.76723 35.6115
306 5VC5 96M 0.000000458 0.58445 35.6401
307 2WQN ADP 0.0000000008845 0.74665 35.8064
308 4USF 6UI 0.00003675 0.49689 35.8553
309 3FHR P4O 0.00000004517 0.62932 36.0119
310 5TA6 79D 0.000001365 0.50637 36.1582
311 3LXN MI1 0.0000000001216 0.73068 36.1635
312 4U0I 0LI 0.00004118 0.43269 36.1905
313 3TKI S25 0.000000005563 0.71007 36.2229
314 5M06 ADP 0.0000001974 0.62596 36.2319
315 5VCV 1N1 0.00000007487 0.58025 36.3344
316 2HY0 306 0.00000004338 0.6663 36.3354
317 4Y93 746 0.000001144 0.52649 36.4407
318 5U6C 7YS 0.000001425 0.55129 36.5079
319 4BHN BH9 0.0000000003688 0.71018 36.5269
320 4CFU 2WC 0.00000000613 0.69595 36.6337
321 4BCM T7Z 0.000001228 0.62512 36.8771
322 4BCQ TJF 0.00000004323 0.54451 36.8771
323 3DAK ANP 0.00000005622 0.65128 36.8966
324 2ZV2 609 0.000000003666 0.72895 36.9128
325 4BCN T9N 0.000000007529 0.70245 37
326 5LMK 6ZK 0.0000008183 0.52067 37.3737
327 4EWH T77 0.00000002739 0.565 37.4545
328 3NW7 LGV 0.000002672 0.57868 37.4593
329 4H3P ANP 0.0000000329 0.64377 37.5
330 2BPM 529 0.0000001733 0.43806 37.5405
331 2XMY CDK 0.00000003161 0.68818 37.5839
332 5JFS 6K0 0.000001675 0.58055 37.6623
333 3G5D 1N1 0.000001935 0.59517 37.7622
334 4JDI ANP 0.0000000001308 0.72934 37.8613
335 1PHK ATP 0.0000000002234 0.68752 37.9195
336 1ZY5 ANP 0.000005719 0.49783 37.9538
337 4A4X JUP 0.0000019 0.51079 37.9928
338 3GC0 AMP 0.000001483 0.5934 37.9939
339 4GJ3 0XP 0.000000006331 0.55772 38.0795
340 5EKO N17 0.00003845 0.4939 38.1356
341 4YMJ 4EJ 0.0000002761 0.66464 38.1579
342 3KRR DQX 0.00000005076 0.6773 38.3051
343 4X7Q 3YR 0.000000001011 0.7109 38.7821
344 4E1Z 0MX 0.0000000135 0.62267 38.8316
345 2WEI VGG 0.0000003503 0.61439 39.0244
346 5JZJ AN2 0.0000000000008382 0.86112 39.0572
347 3GGF GVD 0.0000000006979 0.73976 39.2027
348 5TO8 7FM 0.00001089 0.42634 39.3617
349 3SXS PP2 0.0000003582 0.58311 39.5522
350 3SRV S19 0.0000000003528 0.65633 39.7112
351 2HK5 1BM 0.000003774 0.52713 40
352 4F4P 0SB 0.000003275 0.58789 40.293
353 5JGA 6KC 0.0000000272 0.52749 40.3175
354 3HMO STU 0.0000001001 0.63076 40.3509
355 3C0G 3AM 0.00000001485 0.68843 40.4558
356 5DH3 5BS 0.00000001821 0.63815 40.6349
357 3ORK AGS 0.000000001187 0.63711 41.1576
358 3KN5 ANP 0.00000005799 0.55532 41.2308
359 4BFM ANP 0.00000000000406 0.79348 41.6168
360 3SLS ANP 0.00000000582 0.65085 41.7763
361 2WEL K88 0.0000003227 0.47559 42.8135
362 4CSV STI 0.0001008 0.46624 42.9091
363 1OUK 084 0.00003512 0.56605 42.9379
364 4LOO SB4 0.00001849 0.48641 42.9379
365 5H2U 1N1 0.0000302 0.51228 43.0712
366 4U44 3D9 0.00000000329 0.62805 43.0723
367 2F57 23D 0.0000001408 0.63277 43.2177
368 5DA3 58V 0.0000002835 0.63699 43.3962
369 4I6H 1C8 0.000006611 0.54156 43.5065
370 4XLI 1N1 0.000003154 0.56277 43.6567
371 2VZ6 FEF 0.000000002127 0.72854 43.77
372 4TWP AXI 0.0000006208 0.42739 43.9114
373 2X4Z X4Z 0.0000004799 0.48294 44.2568
374 5IH9 6BF 0.0000001864 0.616 44.4776
375 5A6N U7E 0.000000003729 0.63838 44.8763
376 5GZ9 ANP 0.0000000003397 0.70577 45
377 5UOX 8GY 0.000000002093 0.66935 45.0185
378 5N87 N66 0.000000142 0.48892 45.0479
379 2XK9 XK9 0.000606 0.49316 45.3416
380 4KS7 X4Z 0.0000001397 0.58216 45.5479
381 4YZN 4K5 0.0000000002409 0.6918 45.6446
382 5G1X ADP 0.0000000002586 0.74818 45.9649
383 5L8L ADP 0.00000001032 0.70706 45.9649
384 5LXM ADP 0.0000000001517 0.75869 46.2898
385 2YAK OSV 0.00000001212 0.56063 46.3158
386 2VN9 GVD 0.000000000414 0.59297 46.5116
387 4FG8 ATP 0.0000000003837 0.68998 46.9841
388 5AX9 4KT 0.00000000256 0.69299 47.4026
389 5FBN 5WF 0.00000192 0.56957 47.9705
390 4D2S DYK 0.0000002253 0.6323 48.2394
391 4L9I 8PR 0.00000003266 0.65283 48.5876
392 4WNP 3RJ 0.0000000002148 0.77586 48.7805
393 3E5A VX6 0.000001658 0.52145 49.2537
394 3AQV TAK 0.00002094 0.48356 50
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