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Receptor
PDB id Resolution Class Description Source Keywords
5LB3 1.8 Å EC: 3.6.4.12 CRYSTAL STRUCTURE OF HUMAN RECQL5 HELICASE IN COMPLEX WITH A HOMO SAPIENS HELICASE RECQ TRANSCRIPTION DNA REPAIR STRUCTURAL GENOMISTRUCTURAL GENOMICS CONSORTIUM SGC HYDROLASE
Ref.: INSIGHTS INTO THE RECQ HELICASE MECHANISM REVEALED STRUCTURE OF THE HELICASE DOMAIN OF HUMAN RECQL5. NUCLEIC ACIDS RES. V. 45 4231 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZN E:501;
B:501;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
ADP E:502;
B:502;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MG B:503;
E:503;
Invalid;
Invalid;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LB3 1.8 Å EC: 3.6.4.12 CRYSTAL STRUCTURE OF HUMAN RECQL5 HELICASE IN COMPLEX WITH A HOMO SAPIENS HELICASE RECQ TRANSCRIPTION DNA REPAIR STRUCTURAL GENOMISTRUCTURAL GENOMICS CONSORTIUM SGC HYDROLASE
Ref.: INSIGHTS INTO THE RECQ HELICASE MECHANISM REVEALED STRUCTURE OF THE HELICASE DOMAIN OF HUMAN RECQL5. NUCLEIC ACIDS RES. V. 45 4231 2017
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5LB5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 5LB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5LB5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 5LB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5LB5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 5LB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LB3; Ligand: ADP; Similar sites found with APoc: 728
This union binding pocket(no: 1) in the query (biounit: 5lb3.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 2GKS ADP 0.898876
2 1P9B GDP 1.13122
3 1WUU ANP 1.25313
4 1WRA PC 1.2987
5 6AU6 GDP 1.32626
6 1SVM ATP 1.32626
7 5HR5 ADP 1.34831
8 4IEE AGS 1.34831
9 4JDR FAD 1.34831
10 5JCP GDP ALF 1.43198
11 3EZ2 ADP 1.50754
12 5WX3 COA 1.51515
13 3MGB PAP 1.57303
14 1SVK ALF GDP 1.69972
15 1V8K ANP 1.70732
16 2C78 GNP 1.7284
17 1LQA NDP 1.7341
18 4TMZ GSP 1.73913
19 2GJ8 ALF GDP 1.74419
20 3U6K GDP 1.77665
21 3U6B GDP 1.77665
22 5JBQ GDP 1.77665
23 4G5G GDP 1.77665
24 2BVN GNP 1.78117
25 1D8T GDP 1.78117
26 6DEF GCP 1.79028
27 4ZKD GDP 1.79775
28 2F5Z FAD 1.79775
29 3VZ3 SSN 1.79775
30 4GID 0GH 1.80412
31 4R98 GNH 1.84502
32 5FTB ANP 1.84758
33 5FHD ADP ALF 1.84758
34 2F9L GDP 2.01005
35 5MZN ADP 2.02247
36 1G3M PCQ 2.04082
37 1G3M A3P 2.04082
38 2JJK R15 2.07101
39 3H4S ADP 2.07254
40 4FRZ ADP 2.07254
41 2HCJ GDP 2.08955
42 1OIX GDP 2.09424
43 1Z06 GNP 2.1164
44 5KSZ GCP 2.12264
45 1TQ4 GDP 2.17918
46 4P3Y GDP 2.1978
47 2CHG ANP 2.21239
48 2IXE ATP 2.21402
49 2V2V V12 2.21402
50 4ITM ATP 2.22222
51 5TSH ADP 2.24719
52 4DCT GDP 2.24719
53 5TSH ANP 2.24719
54 5I0H ADP BEF 2.24719
55 1XKV ATP 2.24719
56 5AK0 8V1 2.24719
57 4LYA ATP 2.24719
58 1G7S GDP 2.24719
59 1U0J ADP 2.24719
60 2ZPA ADP 2.24719
61 1S8F GDP 2.25989
62 5LLB 6YZ 2.28137
63 1YRB GDP 2.29008
64 5W75 SUC 2.29592
65 4AG5 ADP 2.29592
66 5W75 GDP 2.29592
67 2B4R AES 2.31884
68 2B4R NAD 2.31884
69 1WF3 GNP 2.32558
70 1Q20 A3P 2.34114
71 1Q20 PLO 2.34114
72 3BFX A3P 2.36486
73 4TL6 ANP 2.37154
74 1J99 AND 2.38908
75 2D7C GTP 2.39521
76 3Q72 GNP 2.40964
77 1GAD NAD 2.42424
78 4E03 ADP 2.42718
79 1VKJ A3P 2.45614
80 1BG2 ADP 2.46154
81 1ION ADP 2.46914
82 3TBK ANP 2.47191
83 1X6V ADP 2.47191
84 5M7P ADP 2.47191
85 1OS1 PYR 2.47191
86 1OS1 ATP 2.47191
87 4PFO ADP 2.47191
88 3HU3 AGS 2.47191
89 5M04 GDP 2.5
90 2RCN GDP 2.51397
91 5ZB0 ADP 2.52525
92 5ZB0 TYD 2.52525
93 1XMV ADP 2.52809
94 1G3Q ADP 2.53165
95 1GOJ ADP 2.53521
96 1K6M AGS 2.5463
97 3FWY ADP 2.54777
98 2QEN ADP 2.57143
99 1D2N ANP 2.57353
100 1F9V ADP 2.59366
101 3DEF GDP 2.67176
102 3CNL GNP 2.67176
103 5G41 AP5 2.69058
104 3A4M ADP 2.69231
105 1IHU AF3 2.69663
106 1IHU ADP 2.69663
107 4ZDJ UTP 2.69663
108 2AJ4 ANP 2.69663
109 4YJ1 ADP 2.69663
110 4RZ3 ADP 2.71186
111 1Y3A GDP 2.73556
112 2DPY ADP 2.73973
113 1S3G AP5 2.76498
114 2OM2 GDP 2.76923
115 1NST A3P 2.76923
116 3TMK T5A 2.77778
117 3NKV GNP 2.85714
118 2A5F GTP 2.85714
119 1BH2 GSP 2.85714
120 5GLN XYP XYP XYP 2.90698
121 1LVK MNT BEF 2.92135
122 4ZG4 VO4 ADP 2.92135
123 5VHC BEF ADP 2.92135
124 2A2C ADP 2.92135
125 2A2C NG1 2.92135
126 4U8P UDP 2.92135
127 1KK1 GNP 2.92683
128 3WR7 COA 2.94118
129 2CBZ ATP 2.95359
130 3CX8 GSP 2.95567
131 1RRC ADP 2.99003
132 2WKQ GTP 3.01205
133 1D2E GDP 3.02267
134 1AQU A3P 3.0303
135 3PQC GDP 3.07692
136 5EXT ADP 3.07692
137 3Q9L ATP 3.07692
138 3N5C GDP 3.08642
139 2O0J ADP 3.11688
140 3B8I OXL 3.13589
141 2A5J GDP 3.14136
142 6FAA ADP 3.14607
143 1YQT ADP 3.14607
144 5H4S RAM 3.16901
145 1DAR GDP 3.18379
146 2Z49 AMG 3.24074
147 5MB4 NAG 3.2419
148 3QKT ANP 3.24484
149 1ZRH A3P 3.28467
150 3BOS CDP 3.30579
151 1FZQ GDP 3.31492
152 1NY5 ADP 3.35917
153 2XAU ADP 3.37079
154 5BN3 ADP 3.37079
155 5N69 ADP 3.37079
156 5LTJ ADP 3.37079
157 5IRN ADP 3.37079
158 4NCN GTP 3.37079
159 4R43 GDP 3.37079
160 4IOK XPO 3.37079
161 4IOK ADP 3.37079
162 5LTJ BEF 3.37079
163 3MD0 GDP 3.38028
164 3ZS9 ADP ALF 3.38983
165 2WOJ ADP ALF 3.38983
166 1OXV ANP 3.39943
167 6G14 G4P 3.40136
168 4BQS K2Q 3.40909
169 4BQS ADP 3.40909
170 3V2U ATP 3.42466
171 5XG5 A2G 3.44828
172 2C77 GNP 3.45679
173 4BFW ZVW 3.45912
174 2CDN ADP 3.48259
175 3FKQ ATP 3.48525
176 5W7Q GDP 3.48525
177 5XKT GNP 3.5
178 2BEK ATP 3.50195
179 4LX0 BEF GDP 3.51288
180 2QG6 NMN 3.51759
181 4V0K GDP 3.5503
182 1Z2A GDP 3.57143
183 1Z83 AP5 3.57143
184 1W4R TTP 3.58974
185 1ZCB GDP 3.59116
186 2IS6 ADP 3.59551
187 5XDR ADP 3.59551
188 1NHX FTB 3.59551
189 1NHX PEP 3.59551
190 2GMV UN8 3.59551
191 2GMV PEP 3.59551
192 2D2F ADP 3.6
193 1QF9 ADP 3.60825
194 1QF9 ALF 3.60825
195 1QF9 C5P 3.60825
196 4RD0 GDP 3.61446
197 3GJ0 GDP 3.61991
198 3GJ5 GDP 3.61991
199 3GJ7 GDP 3.61991
200 2QN6 GDP 3.62319
201 5W76 GDP 3.63636
202 1D5C GDP 3.7037
203 3GJX GTP 3.7037
204 4DKX GDP 3.7037
205 1H65 GDP 3.7037
206 2O66 FLC 3.7037
207 2EFE GNH 3.74532
208 4L2I FAD 3.75723
209 4L2I NAD 3.75723
210 5Z69 AGS 3.76344
211 1M7G ADX 3.79147
212 1M7G AV2 3.79147
213 1M7G ADP 3.79147
214 4H1V GNP 3.79404
215 1NRJ GTP 3.79747
216 2YOH WMJ 3.80952
217 4R2I ANP 3.80952
218 4GOX A3P 3.83387
219 2ORV 4TA 3.84615
220 1RM4 NDP 3.85757
221 3T34 GDP 3.88889
222 1P72 ADP 3.89222
223 5SZH GNP 3.92157
224 3W5J GDP 3.92157
225 2AWN ADP 3.93701
226 5VGR GDP 3.94432
227 2EW1 GNP 3.9801
228 2VVG ADP 4
229 3UIE ANP 4
230 1TAD ALF 4.01235
231 1TAD GDP 4.01235
232 1F6B GDP 4.0404
233 1QHG ATP 4.04494
234 1WDT GTP 4.04494
235 3WXM GTP 4.04494
236 1Q19 SSC 4.04494
237 4XGU ADP 4.04494
238 2R42 FPS 4.05063
239 2XT3 ADP 4.06977
240 3VMF GTP 4.09091
241 2B4D COA 4.09357
242 4KVA GTP 4.12621
243 4LPS GDP 4.13223
244 3QXC ATP 4.13223
245 5K5Z ANP 4.14013
246 3RAB GNP 4.14201
247 4MKG AP5 4.14747
248 3FB4 AP5 4.16667
249 3FVQ ATP 4.17827
250 4TTQ ATP 4.18605
251 3WMX THR 4.18994
252 1KAO GDP 4.19162
253 4X8O AP5 4.20561
254 5IFS ADP 4.21941
255 1E2K TMC 4.22961
256 4GOJ GNP 4.2328
257 1ZD9 GDP 4.25532
258 1G7C 5GP 4.25532
259 5ZXD ATP 4.26966
260 1YTM ATP 4.26966
261 2FAH GDP 4.26966
262 4IHQ ADP 4.26966
263 2BME GNP 4.30108
264 2OBM ADP 4.32277
265 2FH5 GTP 4.32432
266 2OFW ADX 4.32692
267 2ZEJ GDP 4.34783
268 5TIV A3P 4.34783
269 2F3R G5P 4.34783
270 3DC4 ADP 4.36047
271 1JJV ATP 4.36893
272 4ZNL BEF ADP 4.37956
273 1NJF ADP 4.4
274 1NJF AGS 4.4
275 2HF9 GSP 4.42478
276 4WOP CTP 4.44444
277 2W58 ADP 4.45545
278 2OG2 MLI 4.45682
279 2Y8E GNP 4.46927
280 5F90 GLA GAL 4.48718
281 5F90 GLA GAL BGC 5VQ 4.48718
282 5F90 LMR 4.48718
283 2C9O ADP 4.49438
284 1X1R GDP 4.49438
285 4ZI2 GNP 4.51128
286 2XTZ GSP 4.51977
287 3B5J 12D 4.52675
288 4HSE ADP 4.53401
289 1AKY AP5 4.54545
290 5Y6N ADP 4.56621
291 1T5C ADP 4.58453
292 2J5V PCA 4.63215
293 4OHY ANP 4.64037
294 1NN5 2DT 4.65116
295 1NN5 ANP 4.65116
296 3FYH ADP 4.65839
297 1R2Q GNP 4.70588
298 1YZQ GNP 4.70588
299 4KFU ACP 4.71698
300 1F5N GNP 4.7191
301 5KSP GDP 4.73684
302 5GOE GDP 4.73934
303 3QVV A3P 4.74576
304 3QVV 3QV 4.74576
305 5CK5 GDP 4.74684
306 5KUT GDP 4.7619
307 2X77 GDP 4.7619
308 5I34 GDP 4.7619
309 1W0J ADP 4.77941
310 1W0J ADP BEF 4.77941
311 1X8J A3P 4.8433
312 5WC2 ADP 4.86111
313 3RWO GDP 4.86486
314 5IRR GSP 4.87013
315 3QV1 NAD 4.87805
316 5L3W GDP 4.90196
317 2B3D FAD 4.90196
318 4QOS ADP 4.90566
319 1DAK DPU 4.91071
320 1DAK ADP 4.91071
321 2B8T THM 4.93274
322 2GK6 ADP 4.94382
323 4O0L NDP 4.94382
324 2NCD ADP 5
325 5H68 AGS 5
326 4NON GDP 5
327 5WRI A3P 5
328 5BYK OAQ 5.01931
329 5BYK A3P 5.01931
330 2PEZ DAT 5.02793
331 2PEZ GGZ 5.02793
332 6A20 ADP 5.03433
333 1KK8 BEF ADP 5.03597
334 3A1S GDP 5.03876
335 1SKQ GDP 5.05747
336 1TU3 GNP 5.06329
337 4J0Q GDP 5.08083
338 5XC5 GTP 5.11364
339 1B7T ADP 5.12821
340 5X40 ACP 5.13699
341 1G6O ADP 5.15152
342 4TMK T5A 5.16432
343 1Z6T ADP 5.16854
344 2CE7 ADP 5.16854
345 2BIF ANP 5.16854
346 2BIF SIN 5.16854
347 5H7J GCP 5.16854
348 1Z0A GDP 5.17241
349 1OW3 GDP 5.18135
350 2W83 GTP 5.19481
351 1SQ5 ADP 5.19481
352 3VX3 ADP 5.24194
353 2VWT PYR 5.24345
354 1M2O GNP 5.26316
355 4QM7 GTP 5.26316
356 4P4T GDP 5.27778
357 5MEX SZZ 5.2795
358 5MEX PAP 5.2795
359 6CS8 F9Y 5.28053
360 5WRJ A3P 5.28053
361 5UIV ADP 5.28634
362 5H7K GDP 5.28967
363 5UQW GDP 5.29101
364 5OCG GNP 5.29101
365 3B9Q MLI 5.29801
366 3WYA GDP 5.29954
367 2WJG GDP 5.31915
368 3V1Y NAD 5.34125
369 3CPJ GDP 5.38117
370 1R6B ADP 5.39326
371 4IDN GNP 5.39326
372 1FNN ADP 5.39846
373 5TB5 GDP 5.40541
374 5TAR GDP 5.40541
375 4D0N GDP 5.40541
376 6BC0 GSP 5.40541
377 5HPY GDP 5.40541
378 6BCA GSP 5.40541
379 3DZD ADP 5.43478
380 1KMQ GNP 5.43478
381 1Y63 ADP 5.43478
382 4UXH T5A 5.43478
383 3NOJ PYR 5.46218
384 1GXU 2HP 5.49451
385 4NU0 AP5 5.52995
386 1LVG ADP 5.55556
387 2XTN GTP 5.55556
388 4XOI GTP 5.55556
389 3IIJ ADP 5.55556
390 4GBM A3P 5.57276
391 1R0X ATP 5.59441
392 4LJ9 ACP 5.60472
393 4C4P GNP 5.60748
394 5FG3 GDP 5.61798
395 3LRE ADP 5.6338
396 1NF3 GNP 5.64103
397 1TX4 ALF GDP 5.64972
398 3REF GDP 5.6701
399 2GDJ ANP 5.68182
400 3ZFD ANP 5.69801
401 4M9Q GNP 5.72687
402 1I4D GDP 5.72917
403 1A4R GDP 5.75916
404 1A4R GNH 5.75916
405 2NGR GDP 5.75916
406 1GRN GDP 5.75916
407 4ITR GDP 5.75916
408 2ZPT A3P 5.76271
409 4G1V FAD 5.76441
410 3CH5 GDP 5.76923
411 6FA4 GNP 5.78035
412 4FCW ADP 5.78778
413 2WMO GTP 5.78947
414 1Z0K GTP 5.7971
415 1JI0 ATP 5.83333
416 1IBR GNP 5.8427
417 4K81 GTP 5.84795
418 4WZ6 ATP 5.86207
419 5ZBR ANP 5.86667
420 3SBD GNP 5.88235
421 1RYH GNP 5.91133
422 1MH1 GNP 5.91398
423 5O2T GSP 5.91716
424 1MKY GDP 5.92255
425 5E95 GDP 5.95238
426 5J1J ANP 5.96491
427 1G4U GDP 5.97826
428 1LFD GNP 5.98802
429 3X1Z GNP 5.98802
430 4HDO GNP 5.98802
431 2QTV GNP 5.98802
432 1CLU DBG 6.0241
433 5WLB GNP 6.0241
434 2WJH GDP 6.0241
435 1WQ1 GDP 6.0241
436 2WJH FLC 6.0241
437 4PC3 GDP 6.02837
438 3RLF ANP 6.05263
439 2WHX ADP 6.06742
440 2JLR ANP 6.06742
441 1W5T ANP 6.06796
442 1W5T ADP 6.06796
443 4YC7 GNP 6.07735
444 3T5G GDP 6.07735
445 1G41 ADP 6.08108
446 3AB3 GDP 6.09756
447 4KVG GTP 6.15385
448 6BSX E7S 6.17978
449 6BSX GDP 6.17978
450 2FJU GSP 6.17978
451 5YVT NAI 6.21469
452 1HE1 GDP 6.25
453 1KO8 6PG 6.28571
454 2FSH ANP 6.29213
455 2RGX AP5 6.31068
456 1L2T ATP 6.38298
457 2B8W ALF 5GP 6.40244
458 6B8B ADP 6.4257
459 2FFQ GSP 6.43275
460 2FNA ADP 6.44258
461 1Z08 GNP 6.47059
462 3COB ADP 6.50407
463 1IWE IMP 6.51685
464 3EWA ANP 6.52174
465 3NHB ADP 6.53595
466 1U8Z GDP 6.54762
467 2PZE ATP 6.55022
468 2ZFI ADP 6.55738
469 1KY3 GDP 6.59341
470 3TK1 GDP 6.66667
471 4YMU ATP 6.66667
472 5L3V GDP 6.68896
473 5L3S GNP 6.71141
474 1QF5 GDP 6.72854
475 1QF5 RPL 6.72854
476 5KDO GDP 6.75676
477 2Q2Y ADP 6.81199
478 2Q2Y MKR 6.81199
479 2JAQ DCP 6.82927
480 4NE2 SH2 6.88623
481 4NE2 ADP 6.88623
482 3BFV ADP 7.01107
483 5DI3 GNP 7.02703
484 2OZE AGS 7.04698
485 1G16 GDP 7.05882
486 4JLV ADP 7.0632
487 2QQ0 TMP 7.06522
488 2QQ0 ADP 7.06522
489 2QQ0 THM 7.06522
490 2QQ0 ANP 7.06522
491 4HI0 GDP 7.08661
492 2ODE ALF GDP 7.0922
493 1XP8 AGS 7.10383
494 2WIC GNP 7.11611
495 4QRH 0O2 7.14286
496 4YS0 ADP 7.19101
497 2J59 GTP 7.22892
498 1O3Y GTP 7.22892
499 1S9D GDP 7.31707
500 3E70 GDP 7.31707
501 1RE0 GDP 7.31707
502 3EC1 GDP 7.31707
503 1VHT BA3 7.33945
504 1F2U ATP 7.38255
505 1G6H ADP 7.393
506 3KUD GDP 7.40741
507 1GUA GNP 7.40741
508 5EP2 AZU 7.42188
509 4B47 GDP 7.43802
510 4KAX GTP 7.45342
511 2ZE7 DST 7.50988
512 2ZE7 AMP 7.50988
513 1RJ9 GCP 7.56579
514 1HTW ADP 7.59494
515 4PJ3 ANP 7.64045
516 1NVV GNP 7.64045
517 6D5M GNP 7.64045
518 6D5V GNP 7.64045
519 6D56 GNP 7.64045
520 6D59 GNP 7.64045
521 6D5L GNP 7.64045
522 6D55 GNP 7.64045
523 6D5J GNP 7.64045
524 6D5E GNP 7.64045
525 6D5G GNP 7.64045
526 6BVL GNP 7.64045
527 6BVJ GNP 7.64045
528 6D5H GNP 7.64045
529 6BVK GNP 7.64045
530 6BVI GNP 7.64045
531 6BVM GNP 7.64045
532 1WA5 GTP 7.64045
533 3Q85 GNP 7.69231
534 2C5L GTP 7.69231
535 4PPF FLC 7.71429
536 1Z0F GDP 7.82123
537 4OI4 ATP 7.82609
538 1OIV GDP 7.8534
539 4U5X GNP 7.86517
540 4YDS ATP 7.89474
541 5BQ5 ADP BEF 7.93651
542 1UJ2 ADP 7.93651
543 1UJ2 C5P 7.93651
544 5G3Y ADP 7.9646
545 4D0G GTP 8
546 2QZ4 ADP 8.01527
547 2ZR9 DTP 8.02292
548 3T12 GDP ALF 8.08081
549 3T1O GDP 8.08081
550 6C90 ADP 8.08989
551 2E7Z MGD 8.08989
552 4UTG ANP 8.09249
553 2IYL GDP 8.09859
554 1VG9 GDP 8.10811
555 1VG1 GDP 8.10811
556 4D81 ADP 8.12721
557 1PUJ GNP 8.15603
558 4PX9 ADP 8.21918
559 6BCB GSP 8.21918
560 5UPK GNP 8.33333
561 2ZTS ADP 8.36653
562 5J1S ATP 8.3682
563 5JCZ GDP 8.37989
564 3E5H GNP 8.42697
565 3BER AMP 8.43373
566 1CS4 GSP 8.44444
567 1JJ7 ADP 8.46154
568 3BC1 GNP 8.47458
569 2A9K GDP 8.52018
570 5U8U FAD 8.53933
571 3DDC GNP 8.58896
572 4XSH GSP 8.6758
573 1OFH ADP 8.70968
574 2VB6 ADP BEF 8.72483
575 1ZIN AP5 8.75576
576 4A4Z ANP 8.76404
577 2X7I CIT 8.76623
578 1B0U ATP 8.77863
579 1DS6 GDP 8.85417
580 3H86 AP5 8.85417
581 5U32 GDP 8.8983
582 2GCN GDP 8.95522
583 2GCO GNP 8.95522
584 1IN4 ADP 8.98204
585 4BAS GNP 9.04523
586 4R57 ACO 9.09091
587 1OE0 TTP 9.13043
588 1T8U A3P 9.19118
589 1T8U UAP SGN IDS SGN 9.19118
590 4DID GDP 9.21053
591 2PL3 ADP 9.32203
592 6AIC AMP 9.34579
593 2HV8 GTP 9.375
594 5GVR LMR 9.40171
595 6B4K ANP 9.53488
596 1ZJ6 G3D 9.62567
597 3IUY AMP 9.64912
598 6G96 ACO 9.65909
599 5MVR ADP 9.87654
600 5HCN GCP 9.96169
601 1CER NAD 9.96979
602 1FP6 ADP 10.0346
603 2Y65 ADP 10.137
604 1VG8 GNP 10.1449
605 1VG0 GDP 10.1449
606 3MWL 8OX 10.1449
607 1YZN GNP 10.2703
608 1E96 GTP 10.3448
609 1UKZ ADP 10.3448
610 3RNM FAD 10.3448
611 2CJW GDP 10.4167
612 1H74 ADP 10.473
613 2W2X GSP 10.4839
614 4V03 ADP 10.5058
615 4WZA ADP 10.5072
616 4WZA ACP 10.5072
617 6H5E ANP 10.5263
618 5UWH GNP 10.5618
619 4HAT GNP 10.5618
620 5UWU GNP 10.5618
621 5DHF GNP 10.5618
622 6CIT GNP 10.5618
623 5UWP GNP 10.5618
624 5UWO GNP 10.5618
625 5UWT GNP 10.5618
626 5DIF GNP 10.5618
627 5UWJ GNP 10.5618
628 5UWQ GNP 10.5618
629 5UWW GNP 10.5618
630 3M1I GTP 10.5618
631 5UWI GNP 10.5618
632 5DI9 GNP 10.5618
633 5UWS GNP 10.5618
634 5UWR GNP 10.5618
635 3WYF GTP 10.5618
636 4XVU ATP 10.5991
637 4XTR ATP 10.5991
638 4XTR ADP 10.5991
639 1YVD GNP 10.6509
640 4U00 ADP 10.6557
641 5OEC GDP 10.6599
642 4MKF AP5 11.0599
643 2BCG GDP 11.165
644 1GWN GTP 11.2195
645 1W7J ADP BEF 11.2583
646 2HT6 GDP 11.4943
647 1XEX ATP 11.5385
648 3KTA AP5 11.5385
649 4LC1 GDP 11.5727
650 1C3Q TZE 11.6197
651 5L3R GCP 11.6279
652 3TKL GTP 11.7347
653 1Z0J GTP 11.7647
654 5Z2M GTP 11.9318
655 3LXR GDP 11.9792
656 5LEF GTP 12.1212
657 5WDR GNP 12.2807
658 1UPT GTP 12.2807
659 1M7B GTP 12.5
660 3QBT GNP 12.6437
661 4LHW GNP 12.6437
662 3TNF GNP 12.6437
663 3SFV GDP 12.7072
664 1R4A GNP 12.7273
665 1FQK GDP 12.9252
666 3IO3 ADP 12.931
667 2I4I AMP 12.9496
668 3GJ8 GDP 13.0435
669 2Z5F A3P 13.0872
670 5O74 GDP 13.198
671 3ZQ6 ADP ALF 13.2716
672 1SVI GDP 13.3333
673 3DKP ADP 13.4694
674 1XX6 ADP 13.6126
675 2J0V GDP 13.6792
676 2D7D ADP 13.9326
677 5EE5 GTP 14.0845
678 4KBF AMP 14.2466
679 1ZC3 GNP 14.2857
680 1UAD GNP 14.2857
681 2GWH A3P 14.7651
682 2KIN ADP 15
683 3GJ3 GDP 15.1515
684 4CVN ADP 15.3285
685 3B7G ANP 15.6522
686 1QHH ATP 15.6522
687 2G77 GDP 15.6566
688 3P4X ADP 15.7385
689 5BXQ GDP 15.748
690 3KJI ADP 15.748
691 1ZUI SKM 16.0714
692 1FQJ GDP 16.6667
693 2XZ9 PYR 16.9753
694 4Q1A UDP 17.1429
695 4Q1A 2XZ 17.1429
696 3PCR GTP 17.284
697 3MJH GTP 17.6471
698 1J2J GTP 17.7778
699 3ZIA ATP 18.0328
700 3ZIA ADP 18.0328
701 1YZG GDP 18.4358
702 3WY9 GDP 18.75
703 2UZI GTP 19.2308
704 4HDQ GNP 19.2308
705 1CR1 TTP 19.2568
706 3QKD HI0 19.8895
707 3QF7 ANP 20
708 3AQ4 GDP 20.1087
709 1MR3 G3D 20.442
710 2CK3 ANP 20.5479
711 2CK3 ADP 20.5479
712 3DOE GTP 21.875
713 1CXZ GSP 22.093
714 3BD9 A3P 22.5
715 1KSH GDP 22.5806
716 1GOT GDP 23.2877
717 3WYG GTP 23.6842
718 2V7Q ATP 24.2424
719 2V7Q ADP 24.2424
720 4YLG GDP 24.8555
721 1GP2 GDP 25.3521
722 6CRK GDP 25.3521
723 3GJ4 GDP 27.2727
724 5IRC GDP 27.3632
725 1EK0 GNP 31.7647
726 5YV5 ADP 33.3333
727 5YT0 GDP 38.0952
728 2ZJ5 ADP 46.5169
Pocket No.: 2; Query (leader) PDB : 5LB3; Ligand: ADP; Similar sites found with APoc: 25
This union binding pocket(no: 2) in the query (biounit: 5lb3.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5GXU FAD 1.57303
2 4QDI ATP 2.02247
3 1W78 ADP 2.1327
4 1W78 PD8 2.1327
5 1P3D ANP 2.24719
6 2BLE 5GP 2.45232
7 5OC1 FAD 2.92135
8 2JHP SAH 2.92135
9 2Q4V ACO 2.94118
10 1S7N COA 3.84615
11 3G6K POP 3.8961
12 3G6K FAD 3.8961
13 5YGE GLU 4.02299
14 5YGE ACO 4.02299
15 1NAA 6FA 4.04494
16 1GPE FAD 4.04494
17 2V5K OXM 4.52962
18 5FVJ ACO 4.81928
19 1I1D 16G 4.96894
20 4KXL 6C6 5.26316
21 3AB4 THR 5.61798
22 5NB7 8NQ 5.65217
23 1WWZ ACO 11.3208
24 2VHJ ADP 11.7825
25 4KOT CE3 16.0494
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