Receptor
PDB id Resolution Class Description Source Keywords
5L3R 2.5 Å NON-ENZYME: SIGNAL_HORMONE STRUCTURE OF THE GTPASE HETERODIMER OF CHLOROPLAST SRP54 AND ARABIDOPSIS THALIANA ARABIDOPSIS THALIANA CO-TRANSLATIONAL PROTEIN TARGETING SIGNAL RECOGNITION PARTIGTPASE PROTEIN TRANSPORT
Ref.: STRUCTURAL BASIS FOR CONSERVED REGULATION AND ADAPT THE SIGNAL RECOGNITION PARTICLE TARGETING COMPLEX. J.MOL.BIOL. V. 428 2880 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG D:401;
A:402;
C:401;
B:402;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GCP A:401;
B:401;
D:402;
C:402;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
521.208 C11 H18 N5 O13 P3 c1nc2...
GOL B:403;
D:403;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5L3R 2.5 Å NON-ENZYME: SIGNAL_HORMONE STRUCTURE OF THE GTPASE HETERODIMER OF CHLOROPLAST SRP54 AND ARABIDOPSIS THALIANA ARABIDOPSIS THALIANA CO-TRANSLATIONAL PROTEIN TARGETING SIGNAL RECOGNITION PARTIGTPASE PROTEIN TRANSPORT
Ref.: STRUCTURAL BASIS FOR CONSERVED REGULATION AND ADAPT THE SIGNAL RECOGNITION PARTICLE TARGETING COMPLEX. J.MOL.BIOL. V. 428 2880 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 301 families.
1 5L3R - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 221 families.
1 5L3R - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 5L3R - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GCP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GCP 1 1
2 GP3 0.8375 0.948718
3 GDP 0.82716 0.973684
4 GNH 0.817073 0.961039
5 GP2 0.804878 0.987013
6 GTP 0.797619 0.973684
7 G1R 0.788235 0.961039
8 9GM 0.77907 0.948718
9 GSP 0.77907 0.925
10 GNP 0.77907 0.948718
11 G 0.765432 0.960526
12 5GP 0.765432 0.960526
13 G2P 0.758621 0.987013
14 GMV 0.755814 0.948718
15 G2R 0.736264 0.961538
16 Y9Z 0.715789 0.903614
17 GAV 0.703297 0.936709
18 G3A 0.701031 0.948718
19 GKE 0.697917 0.936709
20 GDC 0.697917 0.936709
21 GDD 0.697917 0.936709
22 ALF 5GP 0.696629 0.86747
23 G5P 0.693878 0.948718
24 GPG 0.691489 0.936709
25 GDR 0.690722 0.936709
26 GTG 0.690722 0.91358
27 GFB 0.690722 0.936709
28 GDP AF3 0.688172 0.86747
29 YGP 0.6875 0.879518
30 6CK 0.683673 0.91358
31 GKD 0.67 0.936709
32 JB2 0.67 0.936709
33 GDX 0.663366 0.948718
34 GPD 0.663366 0.925926
35 GDP ALF 0.652632 0.86747
36 ALF GDP 0.652632 0.86747
37 JB3 0.632075 0.925
38 GMP 0.62963 0.857143
39 NGD 0.626168 0.936709
40 G3D 0.610526 0.960526
41 2MD 0.609091 0.870588
42 G G 0.607843 0.924051
43 KB7 0.602151 0.807229
44 G4P 0.597938 0.960526
45 U2G 0.59633 0.91358
46 FEG 0.59633 0.880952
47 GDP 7MG 0.596154 0.888889
48 CAG 0.59292 0.860465
49 MGD 0.59292 0.870588
50 ZGP 0.590909 0.870588
51 0O2 0.59 0.960526
52 CG2 0.585586 0.91358
53 KBD 0.574257 0.807229
54 PGD 0.57265 0.902439
55 MD1 0.57265 0.892857
56 3GP 0.566667 0.922078
57 DBG 0.563025 0.925
58 TPG 0.563025 0.842697
59 FE9 0.550847 0.760417
60 ACP 0.548387 0.922078
61 GH3 0.54 0.973684
62 GCP G 0.538462 0.922078
63 KBJ 0.537736 0.8
64 A G 0.534483 0.911392
65 2GP 0.532609 0.935065
66 G4M 0.53125 0.860465
67 U A G G 0.529915 0.911392
68 GPX 0.529412 0.922078
69 DGI 0.525773 0.924051
70 G A A A 0.521368 0.9
71 IDP 0.520833 0.947368
72 DGT 0.52 0.924051
73 AKW 0.513043 0.869048
74 P1G 0.510417 0.873418
75 G1G 0.504132 0.902439
76 G1R G1R 0.5 0.901235
77 R5I 0.5 0.922078
78 R7I 0.5 0.922078
79 BGO 0.5 0.901235
80 PGD O 0.496 0.831461
81 G U 0.495726 0.878049
82 ACQ 0.494949 0.922078
83 P2G 0.489583 0.860759
84 GGM 0.487395 0.879518
85 MGP 0.485149 0.936709
86 6YZ 0.480392 0.922078
87 6G0 0.480392 0.936709
88 DG 0.479167 0.911392
89 DGP 0.479167 0.911392
90 GPC 0.47541 0.858824
91 G C 0.475 0.878049
92 4TC 0.470085 0.876543
93 IMP 0.46875 0.934211
94 GTA 0.464912 0.91358
95 G2Q 0.453704 0.961538
96 A2D 0.452632 0.871795
97 G G G C 0.452381 0.890244
98 AT4 0.44898 0.8625
99 G7M 0.44898 0.924051
100 APC G U 0.448 0.8875
101 SGP 0.444444 0.807229
102 BA3 0.443299 0.871795
103 G G G RPC 0.439024 0.853659
104 B4P 0.438776 0.871795
105 ADP 0.438776 0.896104
106 AP5 0.438776 0.871795
107 A G C C 0.4375 0.888889
108 ANP 0.436893 0.873418
109 G C C C 0.435115 0.901235
110 AN2 0.434343 0.884615
111 M33 0.43 0.860759
112 AP2 0.428571 0.910256
113 A12 0.428571 0.910256
114 A G U 0.427536 0.86747
115 35G 0.427184 0.909091
116 C2E 0.427184 0.897436
117 PCG 0.427184 0.909091
118 HEJ 0.425743 0.896104
119 ATP 0.425743 0.896104
120 5GP 5GP 0.423077 0.860759
121 G U34 0.422764 0.86747
122 AQP 0.421569 0.896104
123 APR 0.421569 0.871795
124 AR6 0.421569 0.871795
125 5FA 0.421569 0.896104
126 AD9 0.417476 0.873418
127 AGS 0.417476 0.851852
128 SAP 0.417476 0.851852
129 UP5 0.416667 0.851852
130 CA0 0.415842 0.873418
131 ATF 0.415094 0.8625
132 HFD 0.413462 0.851852
133 JSQ 0.413462 0.851852
134 A G U U 0.412587 0.86747
135 KG4 0.411765 0.873418
136 A1R 0.409091 0.841463
137 PRT 0.408696 0.934211
138 01G 0.408696 0.880952
139 APC 0.407767 0.910256
140 DG DG 0.40708 0.86747
141 A4P 0.406504 0.848837
142 UCG 0.406015 0.888889
143 93A 0.405941 0.813953
144 7DD 0.405941 0.883117
145 6AD 0.40566 0.821429
146 ADX 0.401961 0.790698
147 AGO 0.401575 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5L3R; Ligand: GCP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5l3r.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5L3R; Ligand: GCP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5l3r.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5L3R; Ligand: GCP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5l3r.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5L3R; Ligand: GCP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5l3r.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
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