Receptor
PDB id Resolution Class Description Source Keywords
5JZS 2.27 Å EC: 3.7.1.8 HSAD BOUND TO 3,5-DICHLORO-4-HYDROXYBENZOIC ACID MYCOBACTERIUM TUBERCULOSIS HSAD INHIBITOR M. TUBERCULOSIS CHOLESTEROL INFECTION HY
Ref.: INVESTIGATION OF THE MYCOBACTERIAL ENZYME HSAD AS A POTENTIAL NOVEL TARGET FOR ANTI-TUBERCULAR AGENTS U FRAGMENT-BASED DRUG DESIGN APPROACH. BR. J. PHARMACOL. V. 174 2209 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FGZ B:1000;
 Valid;
 none;
 ic50 = 0.54 mM
207.011 C7 H4 Cl2 O3 c1c(c...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2WUF 1.9 Å EC: 3.7.1.8 CRYSTAL STRUCTURE OF S114A MUTANT OF HSAD FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 4,9DSHA MYCOBACTERIUM TUBERCULOSIS HYDROLASE
Ref.: CHARACTERIZATION OF A CARBON-CARBON HYDROLASE FROM MYCOBACTERIUM TUBERCULOSIS INVOLVED IN CHOLESTEROL METABOLISM. J. BIOL. CHEM. V. 285 434 2010
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2WUE - KEK C15 H14 Cl O4 C[C@H](C=C....
2 5JZS ic50 = 0.54 mM FGZ C7 H4 Cl2 O3 c1c(cc(c(c....
3 2WUF Kd = 51 uM KEM C19 H25 O6 C[C@H](C=C....
4 2WUG - HPK C12 H9 O4 c1ccc(cc1)....
5 5JZB ic50 = 0.41 mM 6OT C6 H5 Cl2 N O2 S c1c(cc(cc1....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2WUE - KEK C15 H14 Cl O4 C[C@H](C=C....
2 5JZS ic50 = 0.54 mM FGZ C7 H4 Cl2 O3 c1c(cc(c(c....
3 2WUF Kd = 51 uM KEM C19 H25 O6 C[C@H](C=C....
4 2WUG - HPK C12 H9 O4 c1ccc(cc1)....
5 5JZB ic50 = 0.41 mM 6OT C6 H5 Cl2 N O2 S c1c(cc(cc1....
50% Homology Family (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4LXI - 22J C12 H8 F2 O4 c1ccc(c(c1....
2 4LYE - HPK C12 H9 O4 c1ccc(cc1)....
3 4LXH - C1E C12 H9 Cl O4 c1ccc(cc1)....
4 2WUE - KEK C15 H14 Cl O4 C[C@H](C=C....
5 5JZS ic50 = 0.54 mM FGZ C7 H4 Cl2 O3 c1c(cc(c(c....
6 2WUF Kd = 51 uM KEM C19 H25 O6 C[C@H](C=C....
7 2WUG - HPK C12 H9 O4 c1ccc(cc1)....
8 5JZB ic50 = 0.41 mM 6OT C6 H5 Cl2 N O2 S c1c(cc(cc1....
9 3V1M - HPK C12 H9 O4 c1ccc(cc1)....
10 3V1K - MLA C3 H4 O4 C(C(=O)O)C....
11 2PUH - HPK C12 H9 O4 c1ccc(cc1)....
12 2PUJ - HPZ C12 H10 O4 c1ccc(cc1)....
13 2RHW - C0E C12 H8 F2 O4 c1cc(ccc1C....
14 2RHT - C1E C12 H9 Cl O4 c1ccc(cc1)....
15 3V1N - HPK C12 H9 O4 c1ccc(cc1)....
16 1UK8 - LEA C5 H10 O2 CCCCC(=O)O
17 1UK6 - PPI C3 H6 O2 CCC(=O)O
18 1UKA - SMB C5 H10 O2 CC[C@H](C)....
19 1UK9 - IVA C5 H10 O2 CC(C)CC(=O....
20 1IUP Ki = 2.9 mM ALQ C4 H8 O2 CC(C)C(=O)....
21 1UK7 - BUA C4 H8 O2 CCCC(=O)O
22 1UKB Ki = 0.65 mM BEZ C7 H6 O2 c1ccc(cc1)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: FGZ; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 FGZ 1 1
2 GDE 0.483871 0.666667
3 CHB 0.444444 1
4 QSH 0.411765 0.913043
5 34D 0.40625 0.64
6 PCQ 0.4 0.730769
7 T6C 0.4 0.772727
Similar Ligands (3D)
Ligand no: 1; Ligand: FGZ; Similar ligands found: 1082
No: Ligand Similarity coefficient
1 DHK 0.9884
2 SKM 0.9708
3 4XS 0.9702
4 4NC 0.9697
5 BGC 0.9697
6 7WR 0.9687
7 GTR 0.9683
8 4XV 0.9682
9 UFV 0.9664
10 QSB 0.9663
11 BDP 0.9659
12 GLC 0.9646
13 IHB 0.9641
14 P9P 0.9636
15 ORO 0.9625
16 DHB 0.9623
17 INO 0.9602
18 4A3 0.9596
19 MYJ 0.9595
20 9TW 0.9595
21 93K 0.9595
22 FHB 0.9593
23 D1X 0.9588
24 NNO 0.9584
25 JLZ 0.9583
26 AW5 0.9568
27 3HM 0.9557
28 G3F 0.9535
29 GCS 0.9535
30 XX2 0.9529
31 OXC 0.9525
32 VNL 0.9523
33 2HO 0.9519
34 15L 0.9508
35 DOR 0.9503
36 4CS 0.9475
37 8S0 0.9464
38 C2U 0.9440
39 GAL 0.9433
40 EVA 0.9421
41 GCU 0.9420
42 2AL 0.9416
43 8WO 0.9415
44 F31 0.9410
45 DNC 0.9404
46 HJP 0.9403
47 3HB 0.9401
48 4SX 0.9395
49 3NT 0.9394
50 IJZ 0.9389
51 4AA 0.9387
52 149 0.9387
53 2FG 0.9384
54 3IT 0.9382
55 R8V 0.9378
56 GAB 0.9375
57 DIU 0.9373
58 TTL 0.9373
59 BRT 0.9369
60 FOT 0.9366
61 GCB 0.9361
62 NMJ 0.9361
63 HQD 0.9360
64 SKA 0.9357
65 39O 0.9356
66 L99 0.9353
67 IV2 0.9347
68 12Q 0.9346
69 HQT 0.9344
70 QPR 0.9338
71 0N7 0.9338
72 UNC 0.9338
73 AZ9 0.9336
74 ES0 0.9330
75 ADA 0.9330
76 2D0 0.9328
77 7W1 0.9328
78 5QX 0.9327
79 OVV 0.9326
80 PHB 0.9316
81 53C 0.9315
82 Q88 0.9315
83 J9Q 0.9315
84 KJH 0.9314
85 APZ 0.9312
86 A13 0.9309
87 WCE 0.9303
88 0W1 0.9300
89 LGC 0.9298
90 NPO 0.9297
91 X0V 0.9296
92 ESI 0.9294
93 CWM 0.9292
94 PAB 0.9291
95 QWW 0.9286
96 S76 0.9286
97 3OC 0.9286
98 A7W 0.9283
99 QX2 0.9281
100 YIO 0.9281
101 IFP 0.9278
102 97T 0.9277
103 HBD 0.9273
104 4Z4 0.9273
105 FA3 0.9273
106 67N 0.9272
107 KKN 0.9271
108 JTH 0.9270
109 2H5 0.9270
110 MT0 0.9269
111 4FH 0.9269
112 0HO 0.9267
113 1Y6 0.9266
114 PBZ 0.9265
115 DIN 0.9263
116 FBU 0.9262
117 5HN 0.9262
118 6OT 0.9262
119 3MB 0.9262
120 KT7 0.9252
121 VXX 0.9251
122 MJ2 0.9249
123 4M4 0.9248
124 V55 0.9247
125 DBH 0.9246
126 GLA 0.9246
127 TWO 0.9245
128 AC6 0.9244
129 0P6 0.9240
130 2A7 0.9239
131 KYA 0.9238
132 CWS 0.9237
133 8CM 0.9236
134 E7Z 0.9236
135 EKZ 0.9235
136 8GC 0.9235
137 GZL 0.9234
138 3AB 0.9233
139 826 0.9233
140 SYA 0.9230
141 LDP 0.9228
142 4XR 0.9228
143 KUF 0.9226
144 495 0.9225
145 NOJ 0.9225
146 5WY 0.9223
147 Q6T 0.9221
148 4MA 0.9219
149 6NT 0.9219
150 5IQ 0.9218
151 1SQ 0.9217
152 HQJ 0.9217
153 ICO 0.9216
154 3BZ 0.9213
155 8WT 0.9212
156 URC 0.9212
157 1F1 0.9211
158 EGR 0.9210
159 FE DB1 0.9210
160 XAZ 0.9209
161 3A9 0.9209
162 AJ2 0.9209
163 5SG 0.9208
164 3NY 0.9208
165 069 0.9207
166 GIV 0.9206
167 4P5 0.9203
168 HX3 0.9202
169 OMD 0.9201
170 1NP 0.9200
171 J9T 0.9200
172 PZI 0.9199
173 ASO 0.9199
174 ES7 0.9198
175 ZZ3 0.9198
176 0HN 0.9195
177 TBP 0.9194
178 ONR 0.9194
179 SHG 0.9194
180 92K 0.9192
181 1LM 0.9192
182 24W 0.9192
183 7MH 0.9191
184 3HA 0.9189
185 P72 0.9189
186 GYE 0.9187
187 PRZ 0.9186
188 0F9 0.9186
189 M5K 0.9186
190 JBH 0.9185
191 M1A 0.9177
192 AKH 0.9176
193 M0Q 0.9175
194 3F0 0.9173
195 SYR 0.9171
196 2HU 0.9171
197 9MG 0.9171
198 ES1 0.9168
199 2ZM 0.9168
200 BZ2 0.9168
201 N5J 0.9167
202 5WV 0.9167
203 ISN 0.9167
204 86J 0.9167
205 1LQ 0.9166
206 BEA 0.9164
207 UAN 0.9163
208 4YS 0.9161
209 35C 0.9161
210 7NI 0.9161
211 45L 0.9160
212 O72 0.9159
213 DNF 0.9159
214 GTQ 0.9157
215 QIC 0.9157
216 HQY 0.9156
217 174 0.9151
218 FA6 0.9150
219 LNR 0.9150
220 1GN 0.9149
221 PXL 0.9148
222 JPZ 0.9146
223 FA0 0.9146
224 AHR 0.9145
225 1XN 0.9144
226 SX1 0.9144
227 Z82 0.9143
228 JBK 0.9142
229 M1Q 0.9142
230 DQA 0.9138
231 261 0.9137
232 KBG 0.9136
233 5Q0 0.9136
234 3M0 0.9136
235 5RO 0.9136
236 PFB 0.9136
237 4HM 0.9136
238 PHH 0.9134
239 F12 0.9134
240 EA1 0.9133
241 OVM 0.9133
242 4WL 0.9133
243 C2Y 0.9133
244 2AK 0.9133
245 JR2 0.9131
246 SOR 0.9131
247 42C 0.9130
248 ABI 0.9129
249 4MU 0.9128
250 L5V 0.9128
251 MRW 0.9127
252 4ME 0.9127
253 M2K 0.9127
254 SW7 0.9126
255 KOJ 0.9126
256 CFI 0.9126
257 D48 0.9125
258 FP1 0.9123
259 D07 0.9123
260 NCA 0.9123
261 5RN 0.9122
262 KTW 0.9121
263 I6G 0.9118
264 0JD 0.9117
265 EUG 0.9116
266 4XH 0.9116
267 AZ8 0.9113
268 M6N 0.9110
269 Z5P 0.9110
270 6NI 0.9109
271 TOF 0.9109
272 GUN 0.9108
273 HZQ 0.9107
274 CFP 0.9105
275 MBG 0.9103
276 CFF 0.9101
277 LT2 0.9101
278 6CS 0.9101
279 SOE 0.9101
280 N2Z 0.9100
281 5M0 0.9100
282 3MG 0.9099
283 SHA 0.9098
284 5NI 0.9098
285 HH8 0.9097
286 7W4 0.9096
287 GV9 0.9096
288 4HC 0.9095
289 AZA 0.9094
290 DOB 0.9094
291 2HQ 0.9094
292 BEN 0.9093
293 5JQ 0.9091
294 9FE 0.9089
295 G6D 0.9088
296 Q24 0.9087
297 HLD 0.9087
298 5RG 0.9087
299 2LY 0.9086
300 7MU 0.9085
301 LKA 0.9085
302 HA5 0.9084
303 JAW 0.9083
304 BEZ 0.9082
305 M0W 0.9082
306 MUA 0.9081
307 PE0 0.9080
308 AY4 0.9080
309 6TZ 0.9080
310 4ZA 0.9079
311 DGJ 0.9079
312 E5X 0.9078
313 8W9 0.9077
314 5NU 0.9075
315 3PF 0.9074
316 7B4 0.9073
317 MEW 0.9072
318 3Z8 0.9072
319 54G 0.9070
320 DHS 0.9070
321 AS3 0.9069
322 MO8 0.9069
323 AQO 0.9069
324 JIF 0.9066
325 4M0 0.9062
326 0GZ 0.9062
327 B55 0.9062
328 ICB 0.9061
329 PBC 0.9061
330 CTL 0.9060
331 HIS 0.9060
332 SAL 0.9059
333 15N 0.9059
334 NTZ 0.9059
335 G3E 0.9057
336 3ID 0.9057
337 X6X 0.9057
338 4BZ 0.9057
339 7VS 0.9056
340 UFO 0.9056
341 BSP 0.9055
342 75K 0.9055
343 5OB 0.9055
344 6AP 0.9054
345 BHA 0.9054
346 A2F 0.9052
347 ISZ 0.9052
348 J9W 0.9051
349 5CU 0.9051
350 HDH 0.9050
351 BE2 0.9049
352 BCP 0.9047
353 CN0 0.9046
354 F0J 0.9045
355 PNZ 0.9044
356 AMG 0.9043
357 5XC 0.9042
358 9TZ 0.9042
359 5QY 0.9042
360 FBW 0.9040
361 RXA 0.9038
362 JND 0.9038
363 OTD 0.9038
364 QBK 0.9034
365 AX7 0.9033
366 270 0.9033
367 HNQ 0.9033
368 IGA 0.9031
369 6PC 0.9030
370 VK3 0.9029
371 EV0 0.9028
372 12T 0.9027
373 AZG 0.9027
374 2FQ 0.9027
375 BPN 0.9027
376 8TX 0.9026
377 25W 0.9026
378 141 0.9025
379 ANN 0.9025
380 M1H 0.9025
381 5MK 0.9024
382 BZ3 0.9024
383 9DG 0.9023
384 1XM 0.9022
385 YH7 0.9022
386 52C 0.9022
387 YCP 0.9022
388 XIY 0.9020
389 SE2 0.9020
390 N3W 0.9018
391 BOA 0.9018
392 AX3 0.9017
393 HHA 0.9017
394 G4D 0.9016
395 NQ 0.9015
396 290 0.9015
397 COU 0.9014
398 CH9 0.9014
399 N8Y 0.9012
400 A29 0.9012
401 HLZ 0.9011
402 23A 0.9009
403 JFJ 0.9009
404 PQK 0.9009
405 XAN 0.9008
406 7ZE 0.9008
407 DMD 0.9008
408 4J8 0.9008
409 BTY 0.9007
410 HBA 0.9007
411 HH5 0.9006
412 FA1 0.9006
413 ABV 0.9005
414 ODO 0.9003
415 K5W 0.9003
416 2MI 0.9002
417 BHO 0.9001
418 1M2 0.9000
419 2ZQ 0.9000
420 DRL 0.9000
421 DX4 0.8998
422 ES5 0.8998
423 4KL 0.8998
424 LDR 0.8998
425 717 0.8998
426 0W8 0.8998
427 NIO 0.8997
428 B62 0.8997
429 ET2 0.8996
430 UNU 0.8996
431 JB8 0.8994
432 JDN 0.8994
433 0FN 0.8994
434 XHP 0.8994
435 BAM 0.8993
436 9AP 0.8993
437 173 0.8993
438 GLT 0.8992
439 AC0 0.8992
440 03V 0.8991
441 1XA 0.8990
442 37T 0.8988
443 MAN 0.8988
444 1P7 0.8987
445 SAN 0.8985
446 92P 0.8983
447 4FS 0.8983
448 J5I 0.8983
449 2AQ 0.8982
450 2LP 0.8982
451 AIN 0.8982
452 BNT 0.8980
453 II6 0.8980
454 XCZ 0.8979
455 PZA 0.8979
456 KGK 0.8978
457 ZXD 0.8977
458 0FO 0.8977
459 0CU 0.8976
460 5WU 0.8974
461 NID 0.8974
462 H42 0.8973
463 E1T 0.8972
464 PDC 0.8972
465 GVG 0.8972
466 O2A 0.8970
467 OVP 0.8970
468 51R 0.8969
469 A9P 0.8969
470 M1E 0.8968
471 OCH 0.8967
472 6GU 0.8967
473 8XQ 0.8967
474 HPA 0.8967
475 H4E 0.8966
476 QWN 0.8966
477 692 0.8966
478 EXD 0.8963
479 2A9 0.8962
480 E35 0.8962
481 10L 0.8962
482 OTW 0.8962
483 G2F 0.8962
484 P92 0.8961
485 CLW 0.8961
486 SJ5 0.8960
487 L7T 0.8959
488 FBB 0.8959
489 NBZ 0.8959
490 K3Q 0.8959
491 B60 0.8958
492 ZYR 0.8957
493 M1Z 0.8956
494 JKZ 0.8955
495 9KT 0.8955
496 GAF 0.8955
497 PIY 0.8955
498 MS9 0.8954
499 TSU 0.8954
500 I3A 0.8954
501 G5V 0.8953
502 R20 0.8953
503 DNA 0.8953
504 TTY 0.8953
505 23J 0.8953
506 4FA 0.8951
507 MSR 0.8950
508 9ZE 0.8949
509 9PY 0.8947
510 5CL 0.8947
511 KIB 0.8947
512 ES2 0.8946
513 K2T 0.8946
514 HDL 0.8946
515 EOL 0.8945
516 36R 0.8944
517 KFH 0.8943
518 2FY 0.8942
519 F69 0.8942
520 JFD 0.8940
521 SWD 0.8940
522 XM0 0.8939
523 5JL 0.8938
524 A9O 0.8937
525 INE 0.8936
526 EYK 0.8936
527 OW4 0.8935
528 H5B 0.8934
529 6ME 0.8934
530 GF4 0.8932
531 FUL 0.8931
532 B57 0.8929
533 NDH 0.8929
534 9FL 0.8928
535 1P3 0.8926
536 NIZ 0.8926
537 LI6 0.8925
538 2BG 0.8924
539 FCR 0.8923
540 6FZ 0.8923
541 JKE 0.8923
542 SLS 0.8921
543 42J 0.8921
544 8NX 0.8920
545 1AL 0.8920
546 DQU 0.8920
547 CTS 0.8920
548 TEP 0.8919
549 2HC 0.8919
550 IFL 0.8918
551 PHU 0.8918
552 TPA 0.8916
553 F5B 0.8915
554 ADE 0.8915
555 SWA 0.8915
556 2EC 0.8915
557 DBJ 0.8914
558 FYU 0.8912
559 BTE 0.8911
560 209 0.8909
561 K17 0.8909
562 GXL 0.8909
563 6MP 0.8908
564 TNF 0.8908
565 4SV 0.8907
566 1P8 0.8906
567 ES6 0.8906
568 8IG 0.8906
569 GOX 0.8904
570 9CA 0.8903
571 82I 0.8902
572 LSA 0.8901
573 3XX 0.8901
574 B53 0.8901
575 PYQ 0.8900
576 K22 0.8899
577 PD2 0.8899
578 XXG 0.8899
579 MQN 0.8898
580 X8D 0.8898
581 44V 0.8897
582 SXS 0.8897
583 FDK 0.8896
584 7WV 0.8896
585 6BL 0.8895
586 6VD 0.8895
587 DHQ 0.8895
588 TYL 0.8894
589 4JQ 0.8893
590 H8N 0.8893
591 2PG 0.8893
592 NOY 0.8892
593 6RQ 0.8892
594 8HC 0.8892
595 EMZ 0.8892
596 61M 0.8892
597 3FH 0.8891
598 PIM 0.8890
599 JB5 0.8890
600 JG8 0.8890
601 MVN 0.8890
602 H33 0.8889
603 KJY 0.8889
604 4VP 0.8888
605 5B1 0.8888
606 FDB 0.8887
607 B2J 0.8887
608 XXR 0.8887
609 NPY 0.8886
610 4NM 0.8885
611 RSO 0.8885
612 2F6 0.8884
613 DHY 0.8884
614 NCT 0.8884
615 GJS 0.8883
616 4ZE 0.8883
617 QXW 0.8882
618 IF7 0.8882
619 BP1 0.8882
620 1IT 0.8882
621 2K4 0.8881
622 FAN 0.8881
623 M4T 0.8881
624 DPZ 0.8881
625 DEE 0.8881
626 ASC 0.8880
627 CXF 0.8880
628 ESX 0.8879
629 AMS 0.8879
630 KBB 0.8878
631 PEY 0.8878
632 CPZ 0.8878
633 PA1 0.8877
634 1KP 0.8877
635 GM7 0.8876
636 FBS 0.8876
637 SVN 0.8876
638 9DA 0.8875
639 R9Y 0.8875
640 XQK 0.8874
641 RHU 0.8873
642 NTN 0.8873
643 12M 0.8873
644 MWM 0.8872
645 M4E 0.8871
646 FHN 0.8871
647 BZX 0.8870
648 7HP 0.8869
649 XBZ 0.8869
650 5VM 0.8869
651 FH2 0.8868
652 0FK 0.8868
653 JAE 0.8868
654 5JC 0.8868
655 JBE 0.8868
656 3DO 0.8867
657 EXO 0.8867
658 XQ0 0.8866
659 AEF 0.8866
660 0TU 0.8865
661 QOS 0.8865
662 4YO 0.8865
663 44W 0.8864
664 8ZE 0.8863
665 VNJ 0.8862
666 P3K 0.8862
667 IPB 0.8860
668 F60 0.8859
669 DHR 0.8859
670 XQG 0.8859
671 7WA 0.8857
672 14O 0.8856
673 QUZ 0.8855
674 HKD 0.8854
675 ADZ 0.8854
676 F05 0.8854
677 SNU 0.8853
678 KJU 0.8853
679 ALL 0.8852
680 AEH 0.8850
681 3U4 0.8850
682 9HX 0.8849
683 5H1 0.8849
684 C9E 0.8849
685 CLZ 0.8848
686 H7Y 0.8848
687 TT4 0.8848
688 2YU 0.8847
689 BMA 0.8847
690 NAG 0.8845
691 1WD 0.8844
692 5MI 0.8842
693 8WZ 0.8839
694 A1U 0.8838
695 5LA 0.8837
696 39A 0.8837
697 ES4 0.8837
698 OGA 0.8836
699 DBX 0.8834
700 X0W 0.8834
701 TM7 0.8833
702 28N 0.8833
703 1A7 0.8832
704 M6Z 0.8830
705 1X7 0.8830
706 YRL 0.8827
707 URF 0.8826
708 259 0.8826
709 MAQ 0.8826
710 BK9 0.8825
711 G12 0.8825
712 6M9 0.8825
713 PJW 0.8824
714 GXY 0.8824
715 AAS 0.8824
716 CKA 0.8824
717 K34 0.8824
718 7HQ 0.8822
719 15E 0.8822
720 4AV 0.8821
721 FDR 0.8821
722 4ZC 0.8821
723 VGL 0.8820
724 6AI 0.8820
725 TZF 0.8819
726 AJY 0.8819
727 TNL 0.8818
728 8XL 0.8818
729 BPY 0.8817
730 TSS 0.8817
731 LZM 0.8816
732 DYA 0.8815
733 32X 0.8815
734 SN4 0.8814
735 X05 0.8814
736 DIE 0.8813
737 6M4 0.8813
738 K32 0.8812
739 C2B 0.8811
740 8G0 0.8810
741 TBS 0.8810
742 IAC 0.8810
743 34A 0.8809
744 4JM 0.8809
745 GIO 0.8809
746 PM6 0.8808
747 VOH 0.8808
748 GRE 0.8807
749 GTL 0.8807
750 2O6 0.8806
751 3DM 0.8806
752 N2I 0.8806
753 UNJ 0.8806
754 VGD 0.8806
755 AJV 0.8805
756 HMH 0.8805
757 5MB 0.8805
758 11S 0.8805
759 F4E 0.8804
760 7VJ 0.8803
761 463 0.8802
762 TH7 0.8801
763 Y8I 0.8800
764 3AL 0.8800
765 K6X 0.8799
766 X09 0.8799
767 M5H 0.8799
768 OTR 0.8798
769 MCT 0.8798
770 MFB 0.8798
771 RAT 0.8797
772 SS1 0.8797
773 MWJ 0.8796
774 K97 0.8796
775 6M1 0.8796
776 F9Y 0.8795
777 MR1 0.8794
778 MZG 0.8793
779 MAJ 0.8793
780 FBM 0.8793
781 FBG 0.8792
782 QSC 0.8792
783 ZWZ 0.8790
784 RIB 0.8789
785 NCD 0.8789
786 HT4 0.8786
787 AKG 0.8786
788 G1O 0.8785
789 MHK 0.8785
790 4HO 0.8784
791 3R6 0.8784
792 6XI 0.8784
793 4JL 0.8784
794 LCN 0.8781
795 AMH 0.8781
796 42A 0.8781
797 NGO 0.8780
798 NDM 0.8780
799 BPU 0.8780
800 6R8 0.8779
801 DA4 0.8778
802 12B 0.8778
803 329 0.8777
804 7N0 0.8776
805 KIA 0.8776
806 JBQ 0.8776
807 KTA 0.8775
808 GJP 0.8774
809 M3H 0.8774
810 3Z7 0.8774
811 GCO 0.8774
812 BR9 0.8773
813 2HG 0.8773
814 2D3 0.8772
815 ALE 0.8772
816 XDE 0.8772
817 MWP 0.8772
818 XXP 0.8772
819 ASP 0.8772
820 NVU 0.8771
821 GLU 0.8771
822 FBA 0.8770
823 GCW 0.8770
824 GZ8 0.8769
825 428 0.8768
826 PYD 0.8767
827 FB2 0.8767
828 FK1 0.8763
829 FBV 0.8762
830 RM4 0.8762
831 FUC 0.8761
832 R9S 0.8761
833 F9P 0.8760
834 QAT 0.8759
835 ZB1 0.8758
836 5GU 0.8758
837 8GK 0.8757
838 H4N 0.8756
839 JZ3 0.8756
840 ERH 0.8755
841 R8S 0.8755
842 2CK 0.8755
843 0RW 0.8754
844 9EW 0.8754
845 6KT 0.8754
846 FCB 0.8752
847 TCZ 0.8751
848 ES9 0.8750
849 GOG 0.8750
850 1HN 0.8749
851 JUG 0.8749
852 8NB 0.8749
853 F81 0.8749
854 N7I 0.8747
855 3WA 0.8746
856 OAA 0.8746
857 43M 0.8746
858 AH8 0.8745
859 V1T 0.8745
860 WOO 0.8745
861 LYL 0.8743
862 54X 0.8743
863 8H8 0.8742
864 SYV 0.8742
865 57O 0.8742
866 QAS 0.8740
867 4JJ 0.8740
868 36E 0.8739
869 GLN 0.8739
870 27B 0.8739
871 KJ5 0.8738
872 6DP 0.8738
873 4RU 0.8736
874 CBF 0.8735
875 UEG 0.8734
876 3HP 0.8734
877 M58 0.8732
878 GLY PRO 0.8732
879 PHT 0.8730
880 PAC 0.8730
881 2AC 0.8728
882 36Y 0.8723
883 5NS 0.8722
884 60Q 0.8722
885 4JT 0.8722
886 FB1 0.8722
887 2MP 0.8721
888 TH0 0.8721
889 S2G 0.8720
890 27Y 0.8720
891 1DW 0.8720
892 6F0 0.8719
893 7B3 0.8715
894 TLD 0.8714
895 4NB 0.8714
896 FQI 0.8714
897 4CL 0.8713
898 RM1 0.8713
899 JZ2 0.8712
900 XSP 0.8711
901 C2A 0.8711
902 GJZ 0.8710
903 PMB 0.8710
904 MLT 0.8710
905 PH2 0.8709
906 GNM 0.8709
907 9R5 0.8708
908 RNS 0.8707
909 HMU 0.8705
910 9KH 0.8703
911 XYD 0.8702
912 94W 0.8702
913 PCI 0.8702
914 EDR 0.8701
915 1WC 0.8699
916 PBA 0.8699
917 8NY 0.8698
918 DGL 0.8698
919 PYF 0.8696
920 E3D 0.8696
921 WBU 0.8695
922 4TU 0.8695
923 AA 0.8695
924 TGX 0.8694
925 AL0 0.8694
926 TDR 0.8693
927 F3B 0.8691
928 5ZE 0.8691
929 5WX 0.8691
930 NBG 0.8689
931 20J 0.8689
932 YTX 0.8688
933 SQ7 0.8687
934 2CZ 0.8687
935 P84 0.8686
936 344 0.8685
937 1MC 0.8685
938 K25 0.8684
939 4BL 0.8683
940 47J 0.8683
941 MXD 0.8683
942 THA 0.8682
943 TFU 0.8680
944 PX7 0.8679
945 APS 0.8679
946 SRT 0.8678
947 P7Y 0.8678
948 NSP 0.8674
949 0R0 0.8673
950 293 0.8673
951 ARP 0.8673
952 LZ2 0.8672
953 6QF 0.8671
954 IPZ 0.8671
955 HBX 0.8670
956 PRF 0.8667
957 5UC 0.8667
958 IP0 0.8667
959 5MH 0.8665
960 LQ2 0.8664
961 NTM 0.8663
962 3ZB 0.8662
963 4BY 0.8662
964 YQA 0.8662
965 KDV 0.8661
966 6X9 0.8661
967 2ZX 0.8660
968 AN3 0.8660
969 M4S 0.8659
970 68A 0.8656
971 ADK 0.8656
972 A5E 0.8655
973 30G 0.8654
974 505 0.8654
975 61O 0.8653
976 KLW 0.8653
977 5NE 0.8653
978 BBF 0.8652
979 CKU 0.8652
980 7MX 0.8651
981 EQT 0.8650
982 R8A 0.8650
983 7I2 0.8648
984 7D2 0.8648
985 7VP 0.8648
986 KLK 0.8647
987 ANC 0.8647
988 ZZT 0.8646
989 ICP 0.8645
990 FLV 0.8644
991 TQU 0.8643
992 I3E 0.8641
993 BZE 0.8641
994 BCF 0.8640
995 CXH 0.8640
996 HHR 0.8640
997 226 0.8638
998 1QP 0.8637
999 DEN 0.8637
1000 FRU 0.8637
1001 MFU 0.8635
1002 LRH 0.8634
1003 PQ0 0.8632
1004 13X 0.8630
1005 QBM 0.8630
1006 GBD 0.8629
1007 IOS 0.8628
1008 AX2 0.8628
1009 IFM 0.8627
1010 DQN 0.8627
1011 BNL 0.8627
1012 6LW 0.8625
1013 HFB 0.8625
1014 IBF 0.8625
1015 BZI 0.8625
1016 2ZV 0.8622
1017 NK 0.8622
1018 LT8 0.8622
1019 ANF 0.8621
1020 6UA 0.8621
1021 I7A 0.8621
1022 GIF 0.8620
1023 3C4 0.8620
1024 5VL 0.8620
1025 4JC 0.8619
1026 LMR 0.8618
1027 LZ1 0.8612
1028 PXM 0.8612
1029 GAG 0.8611
1030 3MA 0.8610
1031 IND 0.8610
1032 URS 0.8610
1033 L46 0.8609
1034 QMS 0.8608
1035 YSO 0.8608
1036 4A5 0.8608
1037 MSN 0.8608
1038 MOK 0.8605
1039 H6B 0.8603
1040 E7S 0.8602
1041 3AY 0.8602
1042 0BP 0.8602
1043 BR8 0.8602
1044 SG2 0.8601
1045 3TJ 0.8600
1046 MT5 0.8600
1047 J9N 0.8600
1048 282 0.8599
1049 OXQ 0.8599
1050 60P 0.8598
1051 LAO 0.8598
1052 2GS 0.8597
1053 4JO 0.8596
1054 JA8 0.8595
1055 KYD 0.8593
1056 HXX 0.8591
1057 0R1 0.8590
1058 24B 0.8589
1059 HHS 0.8588
1060 FUF 0.8588
1061 680 0.8588
1062 KBZ 0.8587
1063 MMA 0.8584
1064 RD4 0.8582
1065 MPI 0.8575
1066 BZJ 0.8575
1067 K44 0.8575
1068 OK7 0.8574
1069 1X8 0.8573
1070 9RW 0.8572
1071 F1A 0.8568
1072 BZF 0.8568
1073 CFA 0.8566
1074 5TY 0.8566
1075 SYN 0.8562
1076 GVH 0.8558
1077 PY7 0.8547
1078 H76 0.8546
1079 286 0.8535
1080 SMN 0.8531
1081 DRG 0.8522
1082 OA3 0.8519
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2WUF; Ligand: KEM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2wuf.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2WUF; Ligand: KEM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2wuf.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
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