Receptor
PDB id Resolution Class Description Source Keywords
5JAH 2.06 Å EC: 3.1.1.47 EXPLOITATION OF A NOVEL BINDING POCKET IN HUMAN LIPOPROTEIN- PHOSPHOLIPASE A2 (LP-PLA2) DISCOVERED THROUGH X-F RAGMENT SCREENING HOMO SAPIENS PHOSPHOLIPASE LIPID METABOLISM HYDROLASE
Ref.: EXPLOITATION OF A NOVEL BINDING POCKET IN HUMAN LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 (LP-PLA2) D THROUGH X-RAY FRAGMENT SCREENING. J.MED.CHEM. V. 59 5356 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:501;
 Invalid;
 none;
 submit data
35.453 Cl [Cl-]
6HQ A:502;
 Valid;
 none;
 submit data
142.156 C6 H10 N2 O2 CC1(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LP1 1.91 Å EC: 3.1.1.47 CRYSTAL STRUCTURE OF HUMAN LIPOPROTEIN-ASSOCIATED PHOSPHOLIP COMPLEX WITH A [1.1.1]BICYCLOPENTANE-CONTAINING INHIBITOR AR ESOLUTION. HOMO SAPIENS PLASMA PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE SECRETED ALPHA/BETA-HYDROLASE-FOLD LDL-BOUND; LIPOPROTEIN ASSOCIATEPHOSPHOLIPASE A2 LP-PLA2 GROUP VIIA PLA2 GLYCOPROTEIN HLIPID DEGRADATION POLYMORPHISM SECRETED HYDROLASE-HYDROLINHIBITOR COMPLEX
Ref.: INVESTIGATION OF A BICYCLO[1.1.1]PENTANE AS A PHENY REPLACEMENT WITHIN AN LPPLA2 INHIBITOR. ACS MED CHEM LETT V. 8 43 2017
Members (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YE8 ic50 ~ 1 mM 8U3 C7 H7 F2 N O2 S CS(=O)(=O)....
2 5JAH - 6HQ C6 H10 N2 O2 CC1(C(=O)N....
3 5JAP ic50 = 0.23 uM 6HZ C19 H19 N O Cc1ccccc1c....
4 5LZ4 Kd = 2 uM 7BW C15 H17 F N2 O2 CC1(CC(=O)....
5 5JAL Kd = 980 uM 6HO C11 H10 F N O c1cc(cc(c1....
6 5YE9 ic50 = 355 nM 8U6 C25 H19 N3 O4 S CC(=O)Nc1c....
7 5JAN - 6HP C10 H16 N2 O3 CC(C)COC1=....
8 5JAS ic50 = 1.7 uM 6HW C17 H16 N2 S Cc1ccccc1c....
9 5LZ9 ic50 = 0.12 uM 7BR C19 H23 F N2 O4 S CC1(CCS(=O....
10 5LZ2 ic50 ~ 1 mM 7BX C10 H10 N2 O2 S c1cc(cc(c1....
11 5YE7 ic50 = 3431 nM 8U0 C24 H20 N2 O4 S CC(=O)Nc1c....
12 5JAT ic50 = 0.23 uM 6HR C20 H22 N2 O S Cc1ccccc1c....
13 5LZ8 ic50 = 0.98 uM 7BP C17 H21 F N2 O2 CC(C)(C)[C....
14 5JAU ic50 = 0.0014 uM 6HU C23 H30 N4 O3 Cc1ccccc1c....
15 5LZ7 Kd = 0.53 uM 7BK C20 H19 F N2 O2 C[C@@]1(CC....
16 5YEA ic50 = 5 nM 8U9 C21 H12 Cl F3 N2 O5 S c1cc(ccc1C....
17 5LYY ic50 = 14 uM 7BJ C16 H19 F N2 O3 c1cc(ccc1O....
18 5LP1 ic50 = 0.398 nM 71H C35 H38 F4 N4 O2 S CCN(CC)CCN....
19 5JAR ic50 = 2 uM 6HV C18 H15 N O S Cc1ccccc1c....
20 5LZ5 Kd = 0.45 uM 7K4 C20 H19 F N2 O2 C[C@]1(CC(....
21 5I8P Kd = 0.000000064 M VQ7 C23 H19 Cl F5 N3 O5 S CN1C(=CC(=....
22 5JAD Kd = 3.4 mM FB2 C6 H7 N O2 S c1ccc(cc1)....
23 5JAO - 6HX C13 H12 Cl N Cc1ccc(cc1....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YE8 ic50 ~ 1 mM 8U3 C7 H7 F2 N O2 S CS(=O)(=O)....
2 5JAH - 6HQ C6 H10 N2 O2 CC1(C(=O)N....
3 5JAP ic50 = 0.23 uM 6HZ C19 H19 N O Cc1ccccc1c....
4 5LZ4 Kd = 2 uM 7BW C15 H17 F N2 O2 CC1(CC(=O)....
5 5JAL Kd = 980 uM 6HO C11 H10 F N O c1cc(cc(c1....
6 5YE9 ic50 = 355 nM 8U6 C25 H19 N3 O4 S CC(=O)Nc1c....
7 5JAN - 6HP C10 H16 N2 O3 CC(C)COC1=....
8 5JAS ic50 = 1.7 uM 6HW C17 H16 N2 S Cc1ccccc1c....
9 5LZ9 ic50 = 0.12 uM 7BR C19 H23 F N2 O4 S CC1(CCS(=O....
10 5LZ2 ic50 ~ 1 mM 7BX C10 H10 N2 O2 S c1cc(cc(c1....
11 5YE7 ic50 = 3431 nM 8U0 C24 H20 N2 O4 S CC(=O)Nc1c....
12 5JAT ic50 = 0.23 uM 6HR C20 H22 N2 O S Cc1ccccc1c....
13 5LZ8 ic50 = 0.98 uM 7BP C17 H21 F N2 O2 CC(C)(C)[C....
14 5JAU ic50 = 0.0014 uM 6HU C23 H30 N4 O3 Cc1ccccc1c....
15 5LZ7 Kd = 0.53 uM 7BK C20 H19 F N2 O2 C[C@@]1(CC....
16 5YEA ic50 = 5 nM 8U9 C21 H12 Cl F3 N2 O5 S c1cc(ccc1C....
17 5LYY ic50 = 14 uM 7BJ C16 H19 F N2 O3 c1cc(ccc1O....
18 5LP1 ic50 = 0.398 nM 71H C35 H38 F4 N4 O2 S CCN(CC)CCN....
19 5JAR ic50 = 2 uM 6HV C18 H15 N O S Cc1ccccc1c....
20 5LZ5 Kd = 0.45 uM 7K4 C20 H19 F N2 O2 C[C@]1(CC(....
21 5I8P Kd = 0.000000064 M VQ7 C23 H19 Cl F5 N3 O5 S CN1C(=CC(=....
22 5JAD Kd = 3.4 mM FB2 C6 H7 N O2 S c1ccc(cc1)....
23 5JAO - 6HX C13 H12 Cl N Cc1ccc(cc1....
50% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YE8 ic50 ~ 1 mM 8U3 C7 H7 F2 N O2 S CS(=O)(=O)....
2 5JAH - 6HQ C6 H10 N2 O2 CC1(C(=O)N....
3 5JAP ic50 = 0.23 uM 6HZ C19 H19 N O Cc1ccccc1c....
4 5LZ4 Kd = 2 uM 7BW C15 H17 F N2 O2 CC1(CC(=O)....
5 5JAL Kd = 980 uM 6HO C11 H10 F N O c1cc(cc(c1....
6 5YE9 ic50 = 355 nM 8U6 C25 H19 N3 O4 S CC(=O)Nc1c....
7 5JAN - 6HP C10 H16 N2 O3 CC(C)COC1=....
8 5JAS ic50 = 1.7 uM 6HW C17 H16 N2 S Cc1ccccc1c....
9 5LZ9 ic50 = 0.12 uM 7BR C19 H23 F N2 O4 S CC1(CCS(=O....
10 5LZ2 ic50 ~ 1 mM 7BX C10 H10 N2 O2 S c1cc(cc(c1....
11 5YE7 ic50 = 3431 nM 8U0 C24 H20 N2 O4 S CC(=O)Nc1c....
12 5JAT ic50 = 0.23 uM 6HR C20 H22 N2 O S Cc1ccccc1c....
13 5LZ8 ic50 = 0.98 uM 7BP C17 H21 F N2 O2 CC(C)(C)[C....
14 5JAU ic50 = 0.0014 uM 6HU C23 H30 N4 O3 Cc1ccccc1c....
15 5LZ7 Kd = 0.53 uM 7BK C20 H19 F N2 O2 C[C@@]1(CC....
16 5YEA ic50 = 5 nM 8U9 C21 H12 Cl F3 N2 O5 S c1cc(ccc1C....
17 5LYY ic50 = 14 uM 7BJ C16 H19 F N2 O3 c1cc(ccc1O....
18 5LP1 ic50 = 0.398 nM 71H C35 H38 F4 N4 O2 S CCN(CC)CCN....
19 5JAR ic50 = 2 uM 6HV C18 H15 N O S Cc1ccccc1c....
20 5LZ5 Kd = 0.45 uM 7K4 C20 H19 F N2 O2 C[C@]1(CC(....
21 5I8P Kd = 0.000000064 M VQ7 C23 H19 Cl F5 N3 O5 S CN1C(=CC(=....
22 5JAD Kd = 3.4 mM FB2 C6 H7 N O2 S c1ccc(cc1)....
23 5JAO - 6HX C13 H12 Cl N Cc1ccc(cc1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 6HQ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 6HQ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 6HQ; Similar ligands found: 650
No: Ligand Similarity coefficient
1 XYP 0.9627
2 ABE 0.9588
3 ARB 0.9503
4 ARA 0.9484
5 1XX 0.9470
6 MLT 0.9469
7 XYS 0.9465
8 64K 0.9458
9 IDH 0.9458
10 RIB 0.9453
11 FUC 0.9449
12 AZF 0.9433
13 FUL 0.9425
14 YHO 0.9425
15 Z6J 0.9419
16 R2B 0.9414
17 URF 0.9411
18 PBE 0.9409
19 FUF 0.9408
20 6KX 0.9404
21 SEJ 0.9399
22 IFM 0.9399
23 AHR 0.9394
24 WBU 0.9388
25 RIP 0.9385
26 PAF 0.9375
27 TDR 0.9371
28 KPL 0.9370
29 CIZ 0.9357
30 3ZQ 0.9348
31 LXC 0.9342
32 0MK 0.9338
33 YTB 0.9336
34 DFU 0.9329
35 H3M 0.9327
36 ICP 0.9323
37 1MC 0.9316
38 40O 0.9314
39 CGB 0.9312
40 PYD 0.9311
41 MWM 0.9298
42 XYD 0.9298
43 XXR 0.9297
44 MCT 0.9296
45 A1U 0.9291
46 5UC 0.9291
47 4DX 0.9290
48 ISE 0.9284
49 XBZ 0.9283
50 4HO 0.9279
51 275 0.9279
52 4ZE 0.9276
53 RAM 0.9275
54 DUC 0.9274
55 URA 0.9272
56 4PW 0.9266
57 2AC 0.9265
58 2MP 0.9263
59 PAV 0.9261
60 34A 0.9258
61 CAQ 0.9258
62 H76 0.9254
63 26D 0.9252
64 RSF 0.9249
65 285 0.9249
66 76X 0.9249
67 0TR 0.9248
68 CYT 0.9247
69 BGC 0.9246
70 L89 0.9246
71 JZ2 0.9241
72 3XX 0.9238
73 93Q 0.9236
74 FPY 0.9231
75 9TY 0.9231
76 TH0 0.9226
77 3FA 0.9224
78 4CL 0.9223
79 ASP 0.9223
80 4JJ 0.9222
81 1AB 0.9220
82 2YU 0.9219
83 5MH 0.9218
84 3MC 0.9215
85 92Z 0.9214
86 TM7 0.9214
87 4JO 0.9214
88 FFP 0.9214
89 OXZ 0.9213
90 FLM 0.9213
91 8LG 0.9213
92 43M 0.9208
93 LG3 0.9205
94 PYG 0.9202
95 GMN 0.9202
96 JZ0 0.9201
97 MFU 0.9200
98 I1N 0.9199
99 BAE 0.9199
100 GCS 0.9197
101 3DY 0.9197
102 2C9 0.9195
103 FP2 0.9194
104 BR9 0.9191
105 260 0.9191
106 RCO 0.9188
107 RP7 0.9186
108 CRS 0.9186
109 938 0.9183
110 1AN 0.9182
111 BEW 0.9180
112 EXO 0.9180
113 LG5 0.9179
114 MBD 0.9175
115 OXE 0.9174
116 32O 0.9174
117 8S0 0.9173
118 2AF 0.9172
119 HT4 0.9170
120 27Y 0.9168
121 284 0.9164
122 BDR 0.9163
123 HPY 0.9161
124 KBG 0.9161
125 MWJ 0.9159
126 NOY 0.9158
127 3MH 0.9157
128 JZ3 0.9157
129 8GF 0.9156
130 MZG 0.9155
131 FH2 0.9155
132 2H5 0.9155
133 2XX 0.9155
134 2MY 0.9155
135 LGC 0.9153
136 3CH 0.9145
137 2CH 0.9143
138 HTS 0.9142
139 GLC 0.9141
140 G3F 0.9140
141 5JC 0.9135
142 286 0.9135
143 IUR 0.9134
144 BVF 0.9133
145 GOO 0.9132
146 GAL 0.9131
147 NK 0.9125
148 ITN 0.9119
149 LRH 0.9119
150 HY3 0.9118
151 NEQ 0.9115
152 MNM 0.9113
153 HGQ 0.9112
154 CIG 0.9112
155 G4D 0.9111
156 DMJ 0.9110
157 2FG 0.9105
158 TNE 0.9104
159 6MH 0.9103
160 F05 0.9102
161 PTO 0.9100
162 34V 0.9098
163 AGK 0.9094
164 FLA 0.9092
165 G6D 0.9090
166 B0D 0.9089
167 4XR 0.9088
168 1WG 0.9088
169 O7U 0.9083
170 TLD 0.9080
171 150 0.9080
172 ADE 0.9080
173 DEN 0.9075
174 2CM 0.9074
175 25W 0.9073
176 EDG 0.9070
177 SOE 0.9070
178 IF7 0.9068
179 6LW 0.9068
180 4JU 0.9067
181 2MH 0.9067
182 TMZ 0.9067
183 YAN 0.9066
184 JZ1 0.9066
185 280 0.9065
186 RUU 0.9064
187 948 0.9062
188 7HP 0.9061
189 TMT 0.9058
190 L3Q 0.9055
191 3CE 0.9054
192 DTL 0.9050
193 DUB 0.9050
194 DFB 0.9048
195 FUB 0.9046
196 HPA 0.9045
197 TLA 0.9045
198 KP6 0.9041
199 IDM 0.9041
200 3Z7 0.9041
201 6X8 0.9039
202 4XX 0.9039
203 GLF 0.9038
204 Y8I 0.9037
205 3DO 0.9036
206 SVJ 0.9035
207 1PT 0.9035
208 7CZ 0.9034
209 12M 0.9034
210 2CQ 0.9031
211 45C 0.9029
212 23A 0.9029
213 2DR 0.9027
214 9EW 0.9026
215 FCA 0.9026
216 6M4 0.9024
217 B3R 0.9022
218 ADZ 0.9021
219 0R0 0.9020
220 AKB 0.9016
221 149 0.9015
222 6MP 0.9014
223 HLR 0.9014
224 TM4 0.9014
225 9HX 0.9013
226 R8A 0.9013
227 YIO 0.9011
228 4H2 0.9009
229 JZ9 0.9009
230 0CT 0.9009
231 ASN 0.9006
232 9DA 0.9006
233 HEW 0.9004
234 SVN 0.9001
235 MAN 0.9000
236 GVH 0.9000
237 OXQ 0.8999
238 23W 0.8995
239 GLA 0.8994
240 HSL 0.8992
241 BZF 0.8991
242 M3T 0.8991
243 LCN 0.8991
244 KIV 0.8990
245 KYD 0.8989
246 G2F 0.8988
247 DGJ 0.8987
248 NOJ 0.8987
249 ASO 0.8986
250 ALL 0.8985
251 AUD 0.8982
252 LZ1 0.8982
253 BZI 0.8981
254 95Z 0.8980
255 3RK 0.8979
256 0R1 0.8974
257 X6X 0.8973
258 VAL 0.8971
259 DZX 0.8970
260 6UA 0.8970
261 1DW 0.8969
262 IFL 0.8968
263 ES4 0.8968
264 7WA 0.8963
265 4JP 0.8962
266 IND 0.8961
267 MFB 0.8960
268 47J 0.8960
269 V1L 0.8960
270 GXL 0.8959
271 10L 0.8957
272 ALO 0.8957
273 F4Z 0.8957
274 URQ 0.8955
275 GBD 0.8955
276 WOO 0.8955
277 SFU 0.8954
278 MPI 0.8951
279 BTE 0.8950
280 INS 0.8950
281 TAR 0.8949
282 CP 0.8947
283 PM6 0.8945
284 0RW 0.8944
285 GYE 0.8940
286 5AC 0.8940
287 XUL 0.8938
288 4ZC 0.8938
289 RM4 0.8935
290 TC7 0.8931
291 3U4 0.8931
292 MB3 0.8930
293 FCB 0.8929
294 FRU 0.8929
295 MSN 0.8929
296 1LN 0.8927
297 4SV 0.8926
298 WDL 0.8926
299 ZZT 0.8924
300 SF9 0.8923
301 GAG 0.8921
302 7MH 0.8921
303 FPK 0.8918
304 SAL 0.8917
305 1WD 0.8916
306 NSP 0.8913
307 3SK 0.8912
308 ECE 0.8912
309 BZX 0.8910
310 PSV 0.8910
311 SWD 0.8910
312 HMU 0.8910
313 5DI 0.8910
314 HHQ 0.8910
315 HIO 0.8909
316 BE2 0.8909
317 24B 0.8908
318 ADK 0.8908
319 KOJ 0.8906
320 8EZ 0.8906
321 AX2 0.8905
322 GIO 0.8905
323 HMH 0.8905
324 BP1 0.8904
325 JIF 0.8902
326 GIF 0.8900
327 1AC 0.8899
328 LER 0.8899
329 TFB 0.8898
330 7VJ 0.8898
331 7B4 0.8897
332 CAM 0.8895
333 GAF 0.8895
334 3MA 0.8893
335 RM1 0.8893
336 3AY 0.8891
337 FYU 0.8890
338 SF6 0.8890
339 KSW 0.8887
340 MAE 0.8884
341 RNS 0.8883
342 1DQ 0.8883
343 BMA 0.8877
344 13X 0.8874
345 ICC 0.8870
346 94N 0.8868
347 N8P 0.8868
348 4AX 0.8866
349 HZP 0.8866
350 DAB 0.8866
351 6AI 0.8865
352 CYH 0.8862
353 5ZE 0.8862
354 ARW 0.8860
355 UEG 0.8856
356 7EX 0.8855
357 5AN 0.8851
358 G5V 0.8850
359 J1Z 0.8848
360 JKE 0.8846
361 A2Q 0.8844
362 SR1 0.8843
363 7W4 0.8841
364 ES6 0.8841
365 5RG 0.8841
366 2IM 0.8839
367 HXX 0.8839
368 QOS 0.8839
369 AFR 0.8838
370 F5B 0.8838
371 VNJ 0.8834
372 T6C 0.8834
373 DTI 0.8832
374 2ZX 0.8831
375 261 0.8830
376 BDF 0.8830
377 MMZ 0.8830
378 QUZ 0.8827
379 THR 0.8826
380 ISN 0.8826
381 F81 0.8825
382 EQT 0.8825
383 RHU 0.8824
384 HAI 0.8823
385 NCM 0.8820
386 IPH 0.8820
387 CAH 0.8819
388 L60 0.8819
389 NTM 0.8819
390 7WV 0.8819
391 PRS 0.8817
392 ROR 0.8816
393 CXL 0.8816
394 BR8 0.8814
395 LMR 0.8813
396 DSN 0.8810
397 PXM 0.8809
398 DIG 0.8808
399 KKN 0.8807
400 OAA 0.8806
401 1XN 0.8805
402 XAN 0.8804
403 HQY 0.8802
404 PHT 0.8799
405 P3K 0.8798
406 2MN 0.8798
407 9TZ 0.8795
408 MAK 0.8794
409 IP0 0.8794
410 SYG 0.8793
411 5MB 0.8793
412 LSA 0.8793
413 AMG 0.8793
414 2KT 0.8792
415 GUN 0.8792
416 278 0.8791
417 1GN 0.8790
418 AZA 0.8788
419 6CS 0.8788
420 82I 0.8787
421 C2A 0.8787
422 5Q0 0.8785
423 ZWZ 0.8782
424 5H1 0.8782
425 3SY 0.8782
426 NPY 0.8778
427 MMA 0.8777
428 60P 0.8777
429 ASC 0.8776
430 FBT 0.8776
431 ERH 0.8775
432 ES7 0.8774
433 JZ4 0.8774
434 TH7 0.8774
435 SWA 0.8772
436 2CK 0.8772
437 SYN 0.8771
438 6M9 0.8771
439 3AP 0.8771
440 ES9 0.8769
441 270 0.8767
442 HRZ 0.8766
443 GIV 0.8766
444 DMI 0.8766
445 TAY 0.8765
446 2AP 0.8765
447 HHA 0.8763
448 9PO 0.8763
449 IT9 0.8763
450 ES1 0.8761
451 SER 0.8761
452 LGA 0.8760
453 4HM 0.8760
454 PRO 0.8760
455 HVK 0.8759
456 N5J 0.8758
457 192 0.8757
458 93B 0.8757
459 FCN 0.8757
460 4AP 0.8756
461 1LQ 0.8755
462 M2H 0.8754
463 GTQ 0.8754
464 Q88 0.8754
465 MBN 0.8754
466 290 0.8752
467 5SG 0.8752
468 FSW 0.8752
469 5M0 0.8751
470 6F0 0.8751
471 HYN 0.8751
472 9MG 0.8749
473 9DG 0.8749
474 5IQ 0.8748
475 BEZ 0.8748
476 WOT 0.8746
477 F60 0.8746
478 A2F 0.8745
479 IGA 0.8745
480 98J 0.8744
481 6AP 0.8743
482 ES0 0.8741
483 14O 0.8738
484 R8S 0.8738
485 GRE 0.8734
486 CNL 0.8732
487 FPI 0.8731
488 8H8 0.8730
489 JPZ 0.8730
490 54G 0.8729
491 HH8 0.8729
492 5WV 0.8729
493 D3M 0.8727
494 F0J 0.8727
495 1SQ 0.8727
496 2K4 0.8725
497 282 0.8724
498 5MI 0.8723
499 FDB 0.8721
500 7HQ 0.8721
501 24T 0.8719
502 I3A 0.8717
503 1P7 0.8716
504 6GU 0.8715
505 DCD 0.8714
506 CFP 0.8713
507 XQ0 0.8713
508 PPF 0.8710
509 CEJ 0.8710
510 2PC 0.8709
511 3M0 0.8709
512 4XH 0.8708
513 HIU 0.8707
514 NCA 0.8706
515 11S 0.8706
516 FBV 0.8706
517 DMG 0.8704
518 CWM 0.8703
519 AMC 0.8700
520 ENL 0.8700
521 4YS 0.8700
522 AZG 0.8700
523 UYA 0.8699
524 NBZ 0.8699
525 APY 0.8697
526 5WX 0.8696
527 24W 0.8694
528 51F 0.8694
529 1NP 0.8693
530 BCP 0.8691
531 B53 0.8690
532 PCR 0.8687
533 DXX 0.8686
534 FAC 0.8686
535 BEN 0.8686
536 FOA 0.8684
537 M1A 0.8682
538 MZB 0.8682
539 HQE 0.8682
540 C5J 0.8680
541 O72 0.8680
542 V55 0.8680
543 JFD 0.8680
544 HBX 0.8678
545 SRT 0.8676
546 JBQ 0.8675
547 CRN 0.8674
548 QSC 0.8673
549 ABN 0.8673
550 1XM 0.8672
551 PZA 0.8672
552 JAE 0.8671
553 GLU 0.8671
554 KJY 0.8670
555 39A 0.8670
556 DX4 0.8669
557 ZB1 0.8669
558 PAE 0.8668
559 TBP 0.8667
560 HX3 0.8667
561 2ZV 0.8667
562 YCP 0.8667
563 PXL 0.8667
564 8CL 0.8666
565 EUG 0.8665
566 GXE 0.8665
567 4M4 0.8665
568 HH5 0.8665
569 BOA 0.8664
570 AX7 0.8664
571 KG7 0.8661
572 HYP 0.8661
573 5NU 0.8660
574 SKM 0.8660
575 UNC 0.8659
576 5B1 0.8659
577 H4N 0.8659
578 TFU 0.8659
579 JBH 0.8658
580 ILE 0.8658
581 FK1 0.8657
582 IT2 0.8657
583 TCM 0.8656
584 DBH 0.8655
585 141 0.8655
586 LG4 0.8654
587 HUI 0.8650
588 3WA 0.8649
589 PLQ 0.8647
590 PYC 0.8645
591 NBE 0.8645
592 JBE 0.8645
593 3F0 0.8642
594 E60 0.8641
595 DIE 0.8640
596 1LM 0.8640
597 TMH 0.8639
598 3DM 0.8636
599 BHO 0.8635
600 2EC 0.8634
601 DGY 0.8633
602 MLI 0.8632
603 XQG 0.8632
604 5MK 0.8631
605 1MR 0.8629
606 3HA 0.8627
607 MRZ 0.8625
608 8NY 0.8624
609 25R 0.8624
610 2MI 0.8619
611 P92 0.8619
612 SX1 0.8616
613 S76 0.8615
614 4CS 0.8614
615 NIO 0.8614
616 FPN 0.8612
617 DA1 0.8610
618 PXY 0.8610
619 2LP 0.8608
620 42A 0.8607
621 LZM 0.8606
622 HHN 0.8604
623 UY7 0.8603
624 PY7 0.8603
625 XIX 0.8600
626 3PY 0.8600
627 BAM 0.8600
628 PYJ 0.8599
629 NMJ 0.8598
630 TTO 0.8596
631 6PC 0.8596
632 0W8 0.8594
633 ABV 0.8591
634 0CU 0.8587
635 B24 0.8580
636 IJZ 0.8576
637 HFB 0.8576
638 FMS 0.8576
639 PCA 0.8574
640 CYS 0.8572
641 265 0.8572
642 TCZ 0.8570
643 MBG 0.8566
644 MLA 0.8565
645 FOT 0.8553
646 DMD 0.8533
647 FB1 0.8529
648 3NT 0.8526
649 PIH 0.8523
650 32X 0.8508
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LP1; Ligand: 71H; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5lp1.bio1) has 30 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback