Receptor
PDB id Resolution Class Description Source Keywords
5IZF 2.1 Å EC: 2.7.11.11 COMPLEX OF PKA WITH THE BISUBSTRATE PROTEIN KINASE INHIBITOR HOMO SAPIENS PROTEIN KINASE INHIBITOR BISUBSTRATE OLIGOARGININE PKA TRANSFERASE
Ref.: BIFUNCTIONAL LIGANDS FOR INHIBITION OF TIGHT-BINDIN PROTEIN-PROTEIN INTERACTIONS. BIOCONJUG.CHEM. V. 27 1900 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:401;
A:404;
A:403;
A:402;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
6J9 AZ1 DAR ACA DAR NH2 E:1;
Valid;
none;
Kd = 1.7 nM
801.035 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1RE8 2.1 Å EC: 2.7.11.11 CRYSTAL STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH BALANOL ANALOG 2 MUS MUSCULUS PROTEIN KINASE NATURAL PRODUCT INHIBITOR LIGAND BINDING SPECIFICITY DETERMINANTS CONFORMATIONAL MALLEABILITY TRANSFERASE
Ref.: BALANOL ANALOGUES PROBE SPECIFICITY DETERMINANTS AND THE CONFORMATIONAL MALLEABILITY OF THE CYCLIC 3',5'-ADENOSINE MONOPHOSPHATE-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT BIOCHEMISTRY V. 43 85 2004
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 1REK Ki = 200 nM B8L C32 H36 N2 O7 CC[C@H](C)....
2 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
3 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
4 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
5 1SZM ic50 = 6.35 uM BI4 C27 H26 N4 O2 C[N@]1CCC[....
6 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
7 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
8 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
9 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 1REK Ki = 200 nM B8L C32 H36 N2 O7 CC[C@H](C)....
2 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
3 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
4 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
5 1SZM ic50 = 6.35 uM BI4 C27 H26 N4 O2 C[N@]1CCC[....
6 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
7 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
8 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
9 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
50% Homology Family (492)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 2E9O ic50 = 20 nM A58 C25 H27 N3 O2 CC1CCC(CC1....
2 2WMQ - ZYQ C9 H11 N3 O2 S CC(=O)Nc1n....
3 2BRO ic50 = 1.4 uM DF2 C21 H20 N4 O2 c1ccc(cc1)....
4 2QHN ic50 = 980 nM 582 C13 H13 N3 O CCN1c2cccc....
5 4RVM ic50 = 1 nM 3X7 C23 H21 N5 c1cc(ccc1C....
6 5DLS ic50 = 4.4 nM 5CV C31 H34 N6 O3 CC(C)(CN(C....
7 3TKI ic50 = 0.05 nM S25 C20 H23 N7 O2 S c1cnc(cc1N....
8 2YM5 ic50 = 0.43 uM YM5 C18 H21 N5 O2 c1cc(cc(c1....
9 4HYH ic50 = 1 nM 1AM C22 H22 N6 O3 S COc1ccc2c(....
10 1NVS Ki = 15 nM UCM C24 H15 N3 O3 c1ccc2c(c1....
11 2YDK ic50 = 0.007 uM YDK C17 H20 N4 O2 S c1ccc(cc1)....
12 3OT3 ic50 = 0.005 uM 22K C16 H20 Br N7 Cn1cc(cn1)....
13 2HXQ ic50 = 144 nM 373 C24 H26 N4 O c1ccc2c(c1....
14 2QHM ic50 = 660 nM 7CS C16 H19 N3 O2 CN1[C@H]2C....
15 2BRH ic50 = 22 uM DFW C20 H15 N3 O3 c1ccc(cc1)....
16 2R0U ic50 = 1 nM M54 C25 H22 N4 O2 c1cc(cc(c1....
17 1NVR Ki = 7.8 nM STU C28 H26 N4 O3 C[C@@]12[C....
18 3OT8 ic50 = 0.009 uM MI5 C19 H22 N8 S Cc1cc(sn1)....
19 2YM4 ic50 = 1.5 uM 4YM C21 H22 N6 O3 CCOC(=O)c1....
20 4HYI ic50 = 2 nM 1AO C21 H20 N6 O S c1ccc2c(c1....
21 4RVL ic50 = 41.7 nM 3XL C17 H10 N4 O c1ccc(c(c1....
22 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
23 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
24 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
25 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
26 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
27 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
28 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
29 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
30 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
31 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
32 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
33 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
34 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
35 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
36 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
37 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
38 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
39 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
40 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
41 3JVS Ki = 0.146 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
42 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
43 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
44 2C3L Ki = 0.026 uM IDZ C14 H10 N4 c1ccc2c(c1....
45 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
46 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
47 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
48 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
49 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
50 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
51 1JSV - U55 C10 H11 N5 O2 S c1cc(ccc1N....
52 1OIQ ic50 = 2.9 uM HDU C14 H13 N5 O Cc1c(n2ccc....
53 2W17 ic50 = 0.002 uM I19 C24 H30 F N7 O Cc1ncc(n1C....
54 2VTP ic50 = 0.003 uM LZ9 C17 H11 F3 N4 O2 c1cc(c(c(c....
55 1JVP ic50 = 1.6 uM LIG C15 H11 N3 c1ccc-2c(c....
56 1FVT - 106 C14 H9 Br N4 O3 S c1cc(ccc1/....
57 4KD1 - 1QK C21 H29 N6 O2 CCc1cnn2c1....
58 3LE6 ic50 = 0.035 uM 2BZ C17 H10 Cl N5 O2 Cc1c-2nc(c....
59 2VTI ic50 = 0.66 uM LZ3 C14 H12 N4 O3 S c1ccc2c(c1....
60 3LFS Ki = 2.5 uM A07 C17 H16 Cl N3 O CCCC(=O)Nc....
61 1PXI - CK1 C8 H5 Cl2 N3 S c1cnc(nc1c....
62 4LYN - 1YG C20 H23 N3 O2 S2 C[C@@H](c1....
63 1YKR ic50 = 0.56 uM 628 C20 H14 Cl2 N4 O3 S c1cc(c(c(c....
64 1PXN Ki ~ 0.32 uM CK6 C15 H15 N5 O S Cc1c(sc(n1....
65 2R3J ic50 = 10 nM SCJ C18 H14 Br N5 c1ccc(cc1)....
66 3IG7 ic50 = 9 nM EFP C18 H22 N4 O3 CC(=O)NC1C....
67 2VTS ic50 = 0.03 uM LZC C16 H23 N7 CC(C)Nc1cc....
68 1P2A ic50 = 12 nM 5BN C17 H15 F N4 O c1cc([nH]c....
69 2BHE ic50 = 1 uM BRY C16 H9 Br N2 O2 c1ccc2c(c1....
70 3UNK ic50 = 15 uM 0BY C17 H13 Cl N4 O2 c1ccc(c(c1....
71 2VTQ ic50 = 0.14 uM LZA C16 H17 F2 N5 O2 c1cc(c(c(c....
72 2C68 ic50 = 1.8 uM CT6 C18 H15 Br N5 c1cc(cc(c1....
73 3TIZ - 3TI C17 H13 N O2 c1ccc2c(c1....
74 3PXY ic50 = 5.9 uM JWS C10 H11 N5 O2 COc1ccc(c(....
75 2R3M ic50 = 10 nM SCX C19 H17 F2 N7 CCc1cnn2c1....
76 5JQ5 Kd = 2341 nM I74 C22 H30 N6 O CC(C)c1cnn....
77 2C6O - 4SP C18 H22 N6 O3 S c1cc(ccc1N....
78 1V1K Ki = 35 uM 3FP C22 H23 F4 N5 O2 CN(C)C[C@H....
79 2VTJ ic50 = 1.9 uM LZ4 C10 H9 Cl N4 O2 S c1cc(ccc1N....
80 3EZV - EZV C25 H25 N7 CN1CCN(CC1....
81 3PXZ Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
82 1W0X - OLO C15 H18 N6 O Cn1cnc2c1n....
83 2XMY Ki = 0.11 nM CDK C18 H21 N5 O4 S2 CC1=C(SC(=....
84 2UZO ic50 = 18 uM C62 C14 H10 N2 O5 S2 c1cc(ccc1c....
85 1KE7 ic50 = 8.9 nM LS3 C20 H15 N3 O4 S c1cc2c(cc1....
86 1DM2 - HMD C11 H10 Br N5 O2 C1CNC(=O)C....
87 1DI8 ic50 = 1 uM DTQ C16 H15 N3 O3 COc1cc2c(c....
88 5JQ8 - I73 C22 H30 N6 O CC(C)c1cnn....
89 1GIJ - 2PU C19 H22 N6 O2 c1cc2c(c(c....
90 2R3P ic50 = 900 nM 3SC C19 H12 Cl2 N6 S c1cc(c(c(c....
91 1KE8 ic50 = 1000 nM LS4 C18 H14 N4 O3 S2 c1ccc2c(c1....
92 2C6I ic50 = 11 uM DT1 C18 H22 N6 O3 S c1cc(ccc1N....
93 1PXP Ki ~ 0.22 uM CK8 C17 H19 N5 S Cc1c(sc(n1....
94 2UZN ic50 = 0.03 uM C96 C15 H13 N3 O4 S2 [H]/N=C/1N....
95 2B55 ic50 = 96 nM D31 C24 H31 N5 O2 c1cc-2c(c(....
96 5K4J - 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
97 3PJ8 - 404 C19 H26 N6 O CC[C@H](CO....
98 3LFQ - A28 C17 H15 F2 N3 O CCCC(=O)Nc....
99 2W05 ic50 = 0.001 uM FRT C20 H26 N6 O3 S Cc1ncc(n1C....
100 2XNB Ki = 149 nM Y8L C19 H22 N6 O S CC1=C(SC(=....
101 1HCK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
102 5IEX - 6AF C17 H21 Br N4 O3 S C[C@H]([C@....
103 2R3H ic50 = 20000 nM SCE C13 H13 N5 Cc1cnc2n1c....
104 3LFN Ki = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
105 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
106 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
107 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
108 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
109 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
110 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
111 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
112 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
113 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
114 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
115 2DS1 ic50 = 6.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
116 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
117 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
118 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
119 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
120 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
121 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
122 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
123 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
124 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
125 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
126 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
127 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
128 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
129 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
130 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
131 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
132 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
133 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
134 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
135 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
136 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
137 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
138 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
139 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
140 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
141 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
142 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
143 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
144 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
145 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
146 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
147 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
148 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
149 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
150 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
151 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
152 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
153 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
154 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
155 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
156 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
157 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
158 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
159 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
160 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
161 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
162 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
163 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
164 1H08 - BYP BWP n/a n/a
165 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
166 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
167 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
168 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
169 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
170 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
171 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
172 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
173 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
174 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
175 1PYE ic50 = 0.32 uM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
176 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
177 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
178 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
179 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
180 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
181 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
182 5LI9 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
183 3A8W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
184 3MB6 ic50 = 100 nM 01I C16 H8 O6 c1cc2c(cc(....
185 5M4F - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
186 5CVH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
187 3BQC ic50 ~ 2 uM EMO C15 H10 O5 Cc1cc2c(c(....
188 5CU2 - 54G C8 H8 O3 Cc1ccc(c(c....
189 5MO5 - 4IH C17 H21 Cl N2 O2 S CS(=O)(=O)....
190 5M4I - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
191 5MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
192 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
193 5MOH - YTX C9 H10 O4 COc1cc(ccc....
194 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
195 3OWL ic50 = 0.67 uM 19E C16 H11 Cl N2 O Cc1cnc(c2c....
196 5H8G ic50 < 0.003 uM 5Y4 C23 H29 N9 O CC(=O)Nc1c....
197 5B0X ic50 = 0.02 uM HCK C18 H14 N2 O4 S COc1ccc(cc....
198 5MO8 Kd = 1.64 uM C98 C26 H26 Cl N3 O4 c1ccc(cc1)....
199 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
200 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
201 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
202 5H8E ic50 < 0.003 uM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
203 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
204 5MOE Kd = 500 uM OQC C11 H10 Cl N O c1cc(c(cc1....
205 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
206 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
207 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
208 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
209 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
210 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
211 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
212 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
213 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
214 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
215 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
216 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
217 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
218 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
219 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
220 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
221 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
222 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
223 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
224 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
225 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
226 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
227 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
228 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
229 3PE1 Ki = 0.38 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
230 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
231 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
232 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
233 2ZJW ic50 = 0.04 uM REF C14 H6 O8 c1c2c-3c(c....
234 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
235 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
236 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
237 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
238 3FHR - P4O C21 H16 N4 O c1ccc2c(c1....
239 3R1N - 05B C22 H21 N5 O3 c1cc2c(cc1....
240 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
241 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
242 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
243 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
244 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
245 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
246 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
247 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
248 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
249 2Z7Q - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
250 2Z7R ic50 = 3 nM STU C28 H26 N4 O3 C[C@@]12[C....
251 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
252 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
253 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
254 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
255 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
256 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
257 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
258 5EW9 Ki < 0.01 nM 5VC C22 H21 Cl F N3 O3 S c1cc(nc(c1....
259 4CEG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
260 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
261 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
262 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
263 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
264 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
265 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
266 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
267 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
268 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
269 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
270 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
271 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
272 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
273 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
274 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
275 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
276 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
277 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
278 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
279 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
280 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
281 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
282 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
283 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
284 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
285 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
286 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
287 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
288 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
289 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
290 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
291 4KS7 - X4Z C25 H28 N8 O S Cc1nc2ccsc....
292 1M2P - HNA C14 H7 N O6 c1cc2c(c(c....
293 1LPU - BEN C7 H8 N2 [H]/N=C(c1....
294 2QC6 ic50 = 0.1 uM G12 C10 H6 Br2 O3 CC1=C(C(=O....
295 4ANM ic50 = 28 nM WUL C15 H14 Br N3 O3 c1cc2c(cc1....
296 1DAW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
297 4RLK - E91 C21 H14 N2 O2 c1ccc2c(c1....
298 2OXD - K32 C7 H2 Br4 N2 O c12c(c(c(c....
299 2PVM Ki = 0.36 uM P29 C17 H15 N9 c1ccc(cc1)....
300 1J91 - TBS C6 H Br4 N3 c12c(c(c(c....
301 4DGO ic50 = 0.57 uM 0JW C10 H10 N2 O3 c1cc(c(cc1....
302 3FL5 - TXQ C14 H8 O6 c1cc(c(c2c....
303 3PWD ic50 = 0.22 uM CZ0 C14 H9 N O5 CC1=CC(=O)....
304 3KXH - K66 C11 H9 Br4 N3 O2 CN(C)c1nc2....
305 4DGM ic50 = 1.2 uM AGI C15 H10 O5 c1cc(ccc1C....
306 3PVG - K68 C9 H4 Br4 N2 O2 c1nc2c(n1C....
307 1ZOG Ki = 0.07 uM K37 C8 H4 Br4 N2 S CSc1[nH]c2....
308 2PVJ Ki = 0.005 uM P44 C19 H21 N7 c1ccc(cc1)....
309 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
310 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
311 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
312 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
313 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
314 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
315 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
316 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
317 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
318 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
319 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
320 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
321 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
322 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
323 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
324 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
325 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
326 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
327 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
328 5AUZ ic50 = 98 uM GEN C15 H10 O5 c1cc(ccc1C....
329 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
330 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
331 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
332 5AUY ic50 = 1.6 uM MRI C15 H10 O7 c1cc(c(cc1....
333 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
334 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
335 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
336 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
337 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
338 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
339 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
340 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
341 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
342 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
343 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
344 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
345 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
346 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
347 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
348 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
349 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
350 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
351 3QD4 ic50 = 0.00000001 M 3Q6 C22 H30 N8 O2 C[C@@H]1C[....
352 3RCJ ic50 = 0.8 uM 3RC C16 H13 N5 c1ccc(cc1)....
353 2PE0 - 39Z C14 H12 N2 O2 CC(c1ccc[n....
354 4CT2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
355 5ACK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
356 3HRC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
357 5LVM - ADE C5 H5 N5 c1[nH]c2c(....
358 5MRD ic50 = 36.4 uM S26 C18 H13 Cl N2 O4 S2 CCOC(=O)C1....
359 3ION ic50 = 8 nM 8H1 C28 H27 N5 O3 COc1cc2c3c....
360 1UU7 ic50 = 14 uM BI2 C27 H26 N4 O2 C[N@@]1CCC....
361 3HRF Kd = 10.3 uM P47 C17 H15 Cl O2 c1ccc(cc1)....
362 3QCS ic50 = 0.00000001 M 3Q1 C15 H17 N7 O c1cc2c(cc1....
363 1H1W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
364 4AW1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
365 2PE2 - 464 C28 H30 N6 O3 c1cc(cc(c1....
366 3H9O ic50 = 70 nM 9BD C19 H19 N5 O3 COCCOc1cc2....
367 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
368 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
369 3QD0 ic50 = 0.00000001 M 3Q4 C24 H26 N8 O C[C@@H]1CC....
370 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
371 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
372 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
373 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
374 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
375 3QCX ic50 = 0.00000001 M 3Q2 C16 H19 N7 O C[C@@H]1CO....
376 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
377 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
378 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
379 3QCY ic50 = 0.00000001 M 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
380 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
381 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
382 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
383 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
384 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
385 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
386 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
387 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
388 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
389 4QMP ic50 = 0.014 uM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
390 4U8Z - 3FE C17 H15 N5 O c1cc(cc(c1....
391 4QMX ic50 = 11 uM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
392 4QMT ic50 = 0.01 uM H1N C29 H32 N4 O3 S CCS(=O)(=O....
393 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
394 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
395 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
396 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
397 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
398 4NUS ic50 = 0.005 uM 2NK C22 H21 F2 N3 O CN1CCN(CC1....
399 4NW6 ic50 = 0.004 uM 2NS C23 H20 N4 O4 COc1cc(cc(....
400 4NW5 ic50 = 0.02 uM 2NR C23 H21 F N2 O5 COc1cccc(c....
401 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
402 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
403 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
404 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
405 2W7X ic50 = 138 nM D1A C18 H17 N7 O3 [H]/N=C(N)....
406 4A9U - A9U C27 H28 N4 O2 c1ccc(cc1)....
407 2YCF ic50 = 0.7 nM YCF C19 H24 N10 O3 [H]/N=C(N/....
408 4BDI ic50 = 227.7 uM HAU C14 H19 N3 O2 Cc1ccc(nc1....
409 2YCR ic50 = 69.6 nM HCW C23 H28 N10 O C/C(=NNC1=....
410 2WTJ ic50 = 0.7 uM WTJ C16 H20 N4 O3 S CN(C)CCNC(....
411 2YIT ic50 = 0.29 nM YIT C21 H24 N6 O2 CCC/C(=NNC....
412 2W0J ic50 = 240 nM ZAT C19 H24 N10 O [H]/N=C(N)....
413 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
414 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
415 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
416 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
417 2XBJ ic50 = 0.86 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
418 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
419 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
420 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
421 4FG9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
422 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
423 5L2T - 6ZZ C23 H30 N8 O CN(C)C(=O)....
424 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
425 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
426 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
427 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
428 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
429 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
430 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
431 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
432 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
433 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
434 3GC0 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
435 3MFU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
436 3C0H - AMP C10 H14 N5 O7 P c1nc(c2c(n....
437 3C0I - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
438 3MFS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
439 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
440 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
441 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
442 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
443 4APP Ki = 0.064 uM N53 C33 H36 N6 O3 CC1(c2c(c(....
444 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
445 2YAB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
446 2YAA - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
447 3A62 - STU C28 H26 N4 O3 C[C@@]12[C....
448 3WF9 ic50 = 567 nM FS7 C24 H25 N3 O5 S C[C@H]1CCc....
449 3WF8 ic50 = 232 nM F76 C23 H23 N3 O5 S c1ccc2c(c1....
450 4L3L - 5FI C19 H21 F3 N6 CCc1cncnc1....
451 3WE4 ic50 = 15 nM 5FI C19 H21 F3 N6 CCc1cncnc1....
452 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
453 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
454 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
455 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
456 4O0R Ki = 0.036 uM X4Z C25 H28 N8 O S Cc1nc2ccsc....
457 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
458 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
459 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
460 4EQC ic50 = 0.008 uM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
461 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
462 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
463 4EQU - G6I C30 H24 F3 N7 O2 Cc1ccc(cc1....
464 4JR7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
465 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
466 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
467 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
468 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
469 4OBQ ic50 = 0.065 uM 2QT C20 H20 F N5 O c1cc2c(cc1....
470 4U43 Kd = 48 uM 3D8 C11 H9 N5 c1cc(cnc1)....
471 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
472 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
473 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
474 5F9E ic50 = 0.46 nM 5VS C23 H21 N5 O2 CC1(NC(=O)....
475 1XJD Ki = 0.33 nM STU C28 H26 N4 O3 C[C@@]12[C....
476 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
477 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
478 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
479 5DBX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
480 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
481 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
482 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
483 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
484 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
485 5M56 - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
486 5M4U - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
487 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
488 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
489 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
490 4USF - 6UI C19 H15 N3 O COc1ccc2cc....
491 1V0P ic50 = 0.13 uM PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
492 1V0O ic50 = 5.5 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 6J9 AZ1 DAR ACA DAR NH2; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 6J9 AZ1 DAR ACA DAR NH2 1 1
2 6J9 AZ1 DAR DAR NH2 0.850467 1
3 6J9 AZ1 DAR DAR DAR NH2 0.834862 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1RE8; Ligand: BD2; Similar sites found: 404
This union binding pocket(no: 1) in the query (biounit: 1re8.bio1) has 44 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1RZX ACE VAL LYS GLU SER LEU VAL 0.01876 0.43743 None
2 5EXK 5AD 0.02767 0.42655 1.20846
3 4U98 ACP 0.0002996 0.50416 1.42857
4 3WXL ADP 0.0052 0.4688 1.42857
5 5KJW 53C 0.008335 0.45583 1.42857
6 1W0O SIA 0.0442 0.41242 1.42857
7 3ICS ADP 0.03204 0.4106 1.42857
8 3ICT ADP 0.03698 0.40734 1.42857
9 5DZ2 212 0.0371 0.40939 1.47929
10 4GLW 0XT 0.01151 0.44194 1.63934
11 1TZD ADP 0.00007602 0.56959 1.81818
12 3PNA CMP 0.04222 0.41127 1.94805
13 2YW2 ATP 0.001865 0.45315 2
14 4ANW O92 0.001604 0.42507 2
15 3K5I ADP 0.0113 0.41686 2
16 5JM8 ATP 0.01191 0.41285 2
17 3SHR CMP 0.0132 0.43451 2.00669
18 3MBI HSX 0.03025 0.41919 2.09059
19 4CC6 L5Y 0.01511 0.43554 2.20126
20 3UDZ ADP 0.00002036 0.54952 2.28571
21 5BU2 ADP 0.04936 0.40078 2.28571
22 1IOW ADP 0.002561 0.41234 2.28758
23 1IOW PHY 0.002561 0.41234 2.28758
24 5IGI GMP 0.001997 0.41178 2.32558
25 5IGI ZIT 0.002611 0.40534 2.32558
26 3I0O ADP 0.000009434 0.5996 2.35988
27 2VDF OCT 0.03828 0.41103 2.37154
28 4WJT NAG 0.01593 0.41598 2.39521
29 5XQL C2E 0.004039 0.48216 2.4055
30 2CFM AMP 0.001502 0.48414 2.49554
31 2W68 SIA GAL BGC 0.02664 0.41608 2.5641
32 3AKK ADP 0.00005966 0.5275 2.57143
33 3X01 AMP 0.002701 0.48393 2.57143
34 4PU5 ANP 0.0008479 0.46131 2.57143
35 3ETH ATP 0.001092 0.46008 2.57143
36 3EF0 ALF 0.02933 0.42308 2.57143
37 3IHG VAK 0.01894 0.41552 2.57143
38 1VRP ADP 0.02514 0.41265 2.57143
39 3GXO MQA 0.04857 0.40792 2.57143
40 2I80 G1L 0.04015 0.40548 2.57143
41 2V58 LZJ 0.001468 0.40181 2.57143
42 4RYV ZEA 0.005406 0.45492 2.58065
43 5GZ9 ANP 0.00000006832 0.64386 2.62295
44 3TM0 ANP 0.0006934 0.43929 2.6616
45 3TM0 B31 0.0007779 0.4346 2.6616
46 1ZTH ADP 0.000003545 0.62189 2.71318
47 1ZP9 ATP 0.000003988 0.60349 2.71318
48 3RE4 TO1 0.00003553 0.56941 2.71318
49 3HQP OXL 0.02261 0.42786 2.85714
50 5E89 TD2 0.03144 0.40458 2.8777
51 5K2M ADP 0.0005023 0.46767 2.9304
52 3KYG 5GP 5GP 0.01917 0.41527 3.0837
53 2G30 ALA ALA PHE 0.0008005 0.47036 3.10078
54 2AQX ATP 0.0006661 0.46984 3.11419
55 5MW8 ATP 0.00001493 0.53954 3.14286
56 3TII ANP 0.001523 0.48382 3.14286
57 1PK8 ATP 0.000231 0.47855 3.14286
58 3KAL ADP 0.00395 0.40745 3.14286
59 1GT4 UNA 0.02314 0.41121 3.14465
60 3W0O ADP 0.0000622 0.48729 3.15186
61 3W0O HY0 0.0000622 0.48729 3.15186
62 4D4U FUC GAL NAG 0.03014 0.41927 3.1746
63 4R78 AMP 0.00001851 0.59203 3.23625
64 5D9G GLU ASN LEU TYR PHE GLN 0.04891 0.40776 3.25203
65 4Z1D PEP 0.02333 0.43094 3.26087
66 2GQR ADP 0.006365 0.43892 3.37553
67 4ZGP ADP 0.008164 0.43359 3.41297
68 5KR7 6X9 0.01105 0.43857 3.42857
69 2Z49 AMG 0.03319 0.42704 3.42857
70 5JDA AMP 0.02767 0.4217 3.42857
71 1LCF OXL 0.04432 0.40497 3.42857
72 4XYM A12 0.0007754 0.47495 3.47826
73 3KC1 2T6 0.02937 0.4002 3.56083
74 5D3X 4IP 0.04698 0.4009 3.59281
75 5IQD GNP 0.000003682 0.4652 3.60656
76 5IQD RIO 0.000004431 0.46506 3.60656
77 1CKN GTP 0.01145 0.44206 3.63636
78 1CKM GTP 0.01889 0.40645 3.63636
79 2QK4 ATP 0.0004552 0.51737 3.71429
80 3WVR AMP 0.0004471 0.50069 3.71429
81 4NOS ITU 0.03553 0.41537 3.71429
82 4LH7 1X8 0.005357 0.4619 3.71517
83 1HPG BOC ALA ALA PRO GLU 0.02772 0.41387 3.74332
84 4UWH JXM 0.004286 0.45142 3.82696
85 3BY9 SIN 0.02024 0.43426 3.84615
86 3TDV GDP 0.000008101 0.57462 3.92157
87 4KU7 PCG 0.01697 0.42492 3.92157
88 4OUC 5ID 0.0000001015 0.68346 4
89 4OCJ NDG 0.00008956 0.45841 4
90 5KJZ PCG 0.01285 0.42386 4
91 5NCY 8TK 0.00334 0.41758 4
92 2VK4 TPP 0.008707 0.40803 4
93 1MJT ITU 0.02526 0.41759 4.03458
94 2Q7D ANP 0.003626 0.42417 4.04624
95 4NZN 2OU 0.000702 0.41461 4.24242
96 4NZN ANP 0.000702 0.41461 4.24242
97 5C1P ADP 0.001567 0.47811 4.24837
98 5C1P DAL DAL 0.009771 0.40846 4.24837
99 2IF8 ADP 0.00005629 0.57378 4.28571
100 1IA9 ANP 0.00003501 0.53842 4.28571
101 2VPQ ANP 0.0003269 0.47978 4.28571
102 5LXT ACP 0.0008125 0.46214 4.28571
103 4WOE ADP 0.01827 0.43767 4.28571
104 4WOE 3S5 0.04674 0.41156 4.28571
105 4DS0 A2G GAL NAG FUC 0.02191 0.43353 4.29448
106 4FE2 AIR 0.002184 0.4756 4.31373
107 4FE2 ADP 0.02639 0.41498 4.31373
108 5JAX 6J7 0.02365 0.41074 4.44444
109 1FWV SGA MAG FUC 0.04315 0.40747 4.47761
110 5F90 GLA GAL BGC 5VQ 0.0387 0.41459 4.48718
111 3C8F MT2 0.04223 0.40047 4.4898
112 1I7L ATP 0.0001357 0.49256 4.53074
113 4Y24 TD2 0.02121 0.42362 4.54545
114 5VZ0 ADP 0.000248 0.50819 4.57143
115 4OCV ANP 0.0002589 0.49743 4.57143
116 1P0Z FLC 0.02378 0.42903 4.58015
117 4DFU QUE 0.01706 0.43705 4.65839
118 5C4L 4XR 0.00001483 0.50834 4.6729
119 5C4L SIS 0.0001318 0.47074 4.6729
120 2PYW ADP 0.000002949 0.58278 4.85714
121 5I35 ANP 0.000009136 0.5786 4.85714
122 4AZW ATP 0.00000531 0.57096 4.85714
123 4AZT LY2 0.001615 0.48248 4.85714
124 3V4S ATP 0.006498 0.42486 4.85714
125 1F52 ADP 0.01853 0.42293 4.85714
126 1W2D ADP 0.0006341 0.50378 4.90566
127 1W2D 4IP 0.0008689 0.44415 4.90566
128 4GYI ADP 0.00003286 0.56417 5.03778
129 4PZ6 GMP 0.006597 0.45624 5.14286
130 3E7S AT2 0.01948 0.43474 5.14286
131 3VSV XYP 0.02458 0.42409 5.14286
132 2XG5 EC2 0.008094 0.44044 5.20231
133 2XG5 EC5 0.008094 0.44044 5.20231
134 1TQP ATP 0.000005588 0.55324 5.31915
135 4K7O EKZ 0.03085 0.43214 5.35714
136 2IO8 ADP 0.000342 0.47498 5.42857
137 3ORQ ADP 0.002418 0.44793 5.57029
138 1SU2 ATP 0.02693 0.40489 5.66038
139 3TY5 ATP 0.006542 0.45057 5.71429
140 3TY5 ADP 0.007334 0.43968 5.71429
141 3BP1 GUN 0.01294 0.43322 5.86207
142 3CF6 SP1 0.01989 0.41447 5.98802
143 5HV7 RBL 0.000003902 0.65805 6
144 1OKE BOG 0.03164 0.41439 6
145 4GGZ BTN 0.02573 0.41555 6.08696
146 5TDF ADP 0.0006778 0.47351 6.17284
147 2FB3 MET 0.03734 0.40713 6.17647
148 4RT1 C2E 0.001857 0.46524 6.25
149 4O1P ANP 0.00000006905 0.67419 6.28571
150 2PUL ACP 0.00002486 0.55725 6.28571
151 1EHI ADP 0.0007394 0.47592 6.28571
152 3DNT ATP 0.001086 0.453 6.28571
153 2YRX AMP 0.008052 0.45504 6.57143
154 5TDC NMM ILE PHE SER 0.04323 0.41121 6.57895
155 3TTM PUT 0.03697 0.40916 6.6474
156 4OAV ACP 0.00000008859 0.67747 6.85714
157 5MRH Q9Z 0.0009358 0.50056 6.85714
158 5DYO FLU 0.01473 0.44107 6.88073
159 3LQV ADE 0.002163 0.45672 6.95652
160 5U7W ADE 0.03825 0.42031 7.14286
161 2QHS OCA 0.02531 0.41955 7.173
162 1UNQ 4IP 0.01348 0.44288 7.2
163 5W2I I3P 0.0001691 0.48837 7.393
164 5W2I ADP 0.0001691 0.48837 7.393
165 5CIC 51R 0.003364 0.48103 7.40741
166 4LO2 GAL BGC 0.02517 0.4123 7.43243
167 4LRJ ANP 0.000002647 0.60502 7.69231
168 2P4S DIH 0.03805 0.4067 7.71429
169 5XLY C2E 0.01034 0.42507 7.82918
170 1OBD ATP 0.005333 0.45081 7.84314
171 2QHV OC9 0.01679 0.43307 8.09524
172 2VQD AP2 0.0002765 0.49153 8.28571
173 3ZJX BOG 0.02937 0.42475 8.65052
174 4XMF HSM 0.0002877 0.54672 8.69565
175 3SAO DBH 0.01778 0.43236 8.75
176 2QX0 PH2 0.01065 0.45309 8.80503
177 1YQC GLV 0.02131 0.42803 8.82353
178 2X3J ATP 0.006766 0.42721 8.85714
179 4ZS4 ATP 0.0001766 0.50527 9.12052
180 4JWK CTN 0.03338 0.41898 9.32642
181 5TT6 ATP 0.005987 0.42648 9.71429
182 4OFG PCG 0.008738 0.43978 9.72222
183 1S9D AFB 0.02556 0.41932 9.7561
184 4NS0 PIO 0.03533 0.40578 9.77444
185 3PDT ADP 0.0007087 0.49065 10.1818
186 3TPV ADE 0.01029 0.42188 10.5714
187 2OX9 GAL NAG FUC 0.03935 0.4217 10.7143
188 3EW2 BTN 0.04042 0.40871 11.1111
189 3VPC ADP 0.0003802 0.4809 11.3475
190 3VPB ADP 0.000243 0.47761 11.3475
191 3WCZ CIT 0.002115 0.46818 11.3636
192 3Q60 ATP 0.00008289 0.53157 11.4286
193 3HAV ATP 0.001281 0.50009 11.7057
194 2GQS C2R 0.001472 0.47472 11.8143
195 2GQS ADP 0.01292 0.42375 11.8143
196 2BKK ADP 0.0001135 0.53657 11.8343
197 3WG3 A2G GAL NAG FUC 0.04139 0.41754 12.3596
198 4O4F ATP 0.00008085 0.49817 12.5
199 4O4F IHP 0.0001011 0.48998 12.5
200 5CKW ANP 0.000003981 0.61925 12.8571
201 3VOT ADP 0.00188 0.47902 13.1429
202 4WOH 4NP 0.04145 0.40582 13.253
203 5DMZ ADP 0.00000007579 0.67225 14
204 4OH4 ANP 0.00000002268 0.69746 14.4144
205 5LPZ ADP 0.00000005978 0.67721 14.759
206 2QLU ADE 0.000001482 0.67306 15.2866
207 5HWV MBN 0.009266 0.45173 15.3846
208 4IJP 1EH 0.00000006768 0.44165 15.4286
209 4I94 ANP 0.0000004532 0.64266 15.6667
210 2RIO ADP 0.00000003467 0.69748 16
211 5LPB ADP 0.0000006928 0.65906 16.2162
212 4WW7 AMP 0.000000255 0.62501 18.7739
213 4CYI ATP 0.00004513 0.52796 18.8571
214 3VHE 42Q 0.000001375 0.55395 19.7143
215 3H0L ADP 0.04047 0.41228 20.2128
216 4YZC STU 0.00000004819 0.58148 20.5714
217 5C03 AGS 0.00001357 0.56384 21.345
218 4Y0X ADP 0.00000226 0.61586 22
219 5DZT AMP 0.004566 0.46854 22.2857
220 2PZI AXX 0.0002876 0.51588 22.8571
221 4WOV 3SM 0.00005476 0.5528 23.0284
222 4Q5H ANP 0.000003524 0.59202 23.6842
223 3HMO STU 0.0000001358 0.66836 25.4386
224 4CRL C1I 0.000004124 0.52206 26.8473
225 1Q8Y ADP 0.00000002399 0.67948 26.8571
226 1Q8Y ADE 0.000001055 0.65882 26.8571
227 4IDT T28 0.00000001296 0.71847 27.1429
228 3VRY B43 0.0000282 0.51786 27.1429
229 5BVE 4VG 0.0000000001447 0.55299 27.4238
230 5N87 N66 0.00000002053 0.6001 27.476
231 5KO1 6UY 0.000001792 0.61334 27.5618
232 1U5R ATP 0.000000002596 0.74275 27.5862
233 4E93 GUI 0.00000002098 0.61565 27.7143
234 5MY8 RXZ 0.000009475 0.53825 27.7143
235 3C1X CKK 0.0002567 0.48865 27.7143
236 4BTK DTQ 0.0000003699 0.63912 27.8932
237 3UIM ANP 0.00000005609 0.67854 27.9141
238 5UIU 8CG 0.000000769 0.56412 28.1734
239 5T8O 76Z 0.00000004645 0.6662 28.3668
240 4H3P ANP 0.00000002687 0.69391 28.5714
241 4H3Q ANP 0.00000003335 0.65775 28.5714
242 3PP0 03Q 0.000002469 0.5582 28.6982
243 4XH0 ADP 0.00002356 0.59817 28.8571
244 3LXN MI1 0.0000000001471 0.78184 28.9308
245 4QTB 38Z 0.00000001071 0.64508 29.1429
246 3KMW ATP 0.0001685 0.51644 29.1513
247 1VJY 460 0.00000002856 0.61043 29.3729
248 3H9R TAK 0.00001779 0.59295 29.697
249 4UX9 ANP 0.0000000007717 0.74854 29.7143
250 3GNI ATP 0.0000001058 0.64964 29.7143
251 2H8H H8H 0.000001534 0.60939 29.7143
252 4BKJ STI 0.00179 0.44026 29.8413
253 2B9I ADP 0.000000002704 0.7419 30
254 2B9J ADP 0.000000005225 0.73784 30
255 2B9H ADP 0.000000004528 0.72184 30
256 3E8N ATP 0.000001658 0.49999 30.2053
257 3E8N VRA 0.000001658 0.49999 30.2053
258 5HCY 60D 0.0000008679 0.5128 30.2115
259 5EOB 5QQ 0.00001978 0.46946 30.4075
260 2B9F ADP 0.00000001482 0.70635 30.5714
261 2WU6 DKI 0.0000000427 0.65296 30.5714
262 5LXC 7AA 0.00000000103 0.44579 30.5714
263 4D2S DYK 0.0000004294 0.66073 30.6338
264 4NFN 2KC 0.00002206 0.55979 30.7443
265 5W4W 9WG 0.00001824 0.50479 31.1178
266 4KBA 1QM 0.00004466 0.50088 31.1178
267 4GJ3 0XP 0.000000009672 0.63462 31.1258
268 1OPK P16 0.00002641 0.49841 31.1429
269 4P5Z Q7M 0.00009009 0.45831 31.1429
270 3ALN ANP 0.0000003013 0.62862 31.1927
271 4CLI 5P8 0.00002164 0.46563 31.1927
272 5X8I SQZ 0.0000000009372 0.76404 31.2139
273 4E1Z 0MX 0.000000003384 0.70205 31.2715
274 1CM8 ANP 0.00000002458 0.70482 31.4286
275 5JGA 6KC 0.000003256 0.53016 31.4286
276 3LXK MI1 0.000000005577 0.6633 31.4985
277 3KRR DQX 0.0000000173 0.49025 31.5254
278 3NW7 LGV 0.0001432 0.43312 31.5961
279 4NST AF3 0.00000004994 0.85675 31.7143
280 4F9C 0SX 0.000000007794 0.72931 31.7143
281 4NST ADP 0.00000005089 0.68057 31.7143
282 4IZY 1J2 0.0000003085 0.62815 31.7143
283 4U44 3D9 0.0000009375 0.61969 31.9277
284 1Y57 MPZ 0.0000004903 0.60569 32
285 5HVJ ANP 0.00000006611 0.74809 32.0635
286 5BYZ 4WE 0.0000001163 0.59181 32.1839
287 3KRL KRL 0.00001181 0.54937 32.2388
288 4Y93 746 0.000007814 0.54185 32.2857
289 4LOO SB4 0.000166 0.51152 32.2857
290 2OO8 RAJ 0.001219 0.45791 32.4921
291 4YLL 4E3 0.00000004571 0.65164 32.5714
292 4Y8D 49J 0.0000002655 0.64605 32.6471
293 1K3A ACP 0.000006793 0.59926 32.7759
294 3ORK AGS 0.000001891 0.56837 32.7974
295 4Y85 499 0.00001826 0.56384 32.8313
296 4NM5 ADP 0.00000004699 0.65111 32.8571
297 5TO8 7FM 0.000007279 0.49446 32.9787
298 4AT3 LTI 0.00004587 0.49261 33.1104
299 3PTG 932 0.0000009317 0.66172 33.1429
300 3TTI KBI 0.0000008604 0.57225 33.1429
301 4WHZ 3NL 0.0000008374 0.49796 33.1429
302 5EFQ ADP 0.0000000595 0.6773 33.4294
303 5AWM ANP 0.0000001439 0.69485 34
304 3PLS ANP 0.00000003351 0.6982 34.2282
305 2JLD AG1 0.000000003052 0.64237 34.2857
306 3E7O 35F 0.00003141 0.49174 34.2857
307 4QMN DB8 0.000002046 0.52557 34.5161
308 3F7Z 34O 0.0000001572 0.657 34.5714
309 3ZRM ZRM 0.000001247 0.61373 34.5714
310 4ASE AV9 0.00008026 0.49029 35.1275
311 4YZN 4K5 0.000000001285 0.7208 35.1916
312 4EWH T77 0.000001289 0.56494 35.2727
313 5NKB 8ZT 0.00003699 0.46337 35.2941
314 5JFS 6K0 0.00008511 0.45354 35.3896
315 4YMJ 4EJ 0.0000003804 0.69961 35.5263
316 2HK5 1BM 0.000002171 0.58893 35.5556
317 2BPM 529 0.000000001176 0.58758 35.5987
318 4XV1 904 0.000008546 0.50989 35.6164
319 5HES 032 0.000009777 0.40013 35.8306
320 5H2U 1N1 0.0003279 0.49729 35.9551
321 1UNH IXM 0.00000005197 0.70774 35.9589
322 3O0G 3O0 0.00000001365 0.43714 35.9589
323 2F57 23D 0.000004019 0.60332 36
324 5DA3 58V 0.000005381 0.61239 36.2264
325 2A19 ANP 0.0000001119 0.70058 36.2676
326 2XVD AS6 0.00001561 0.5156 36.4238
327 4X7Q 3YR 0.0000000005325 0.77585 36.5385
328 3GC8 B45 0.000009323 0.55404 36.5714
329 5M06 ADP 0.00001208 0.57935 36.5942
330 4CFU 2WC 0.00000001021 0.73348 36.6337
331 5HX8 66P 0.000000003132 0.68076 36.755
332 4G31 0WH 0.0001261 0.46497 36.7893
333 1JPA ANP 0.00001247 0.60166 36.859
334 4BCQ TJF 0.0000002354 0.68365 36.8771
335 4BCM T7Z 0.0000006336 0.68098 36.8771
336 4EUU BX7 0.00000004906 0.63021 36.9906
337 4BCN T9N 0.0000000141 0.73678 37
338 4CQE CQE 0.000004127 0.57011 37.0504
339 4M69 ANP 0.000002924 0.58295 37.0607
340 2HY0 306 0.0000001391 0.68582 37.2671
341 4JDI ANP 0.0000001098 0.64891 37.2832
342 4AG8 AXI 0.000005364 0.50996 37.3418
343 5LMK 6ZK 0.000001523 0.62445 37.3737
344 4ITH RCM 0.01639 0.40651 37.415
345 3SLS ANP 0.0000003991 0.61618 37.5
346 3SLS 77D 0.003835 0.44586 37.5
347 5U6C 7YS 0.000001818 0.58628 37.7778
348 3IGO ANP 0.0000005438 0.61008 38
349 2Y6O 1N1 0.00003572 0.52754 38.1443
350 4K33 ACP 0.00000002945 0.68348 38.1538
351 2OFV 242 0.00006552 0.46943 38.2671
352 2PVF ACP 0.000000004392 0.74154 38.3234
353 5JKG 6LF 0.00004463 0.46936 38.5852
354 4BHN BH9 0.000000008374 0.70062 38.6228
355 5HQ0 LZ9 0.00000000368 0.71715 38.7417
356 3GQI ACP 0.000000008439 0.71812 38.9571
357 5MJA 7O3 0.000005612 0.59605 39.0164
358 5VC5 96M 0.000002108 0.55605 39.1003
359 3DLS ADP 0.000000005726 0.42896 39.1045
360 5TA6 79D 0.000009333 0.52917 39.1061
361 4FF8 14S 0.001152 0.49018 39.3189
362 1U59 STU 0.00000000432 0.73211 39.3728
363 4FL3 ANP 0.0000006219 0.60744 39.7143
364 4XLI 1N1 0.000003662 0.5981 39.9254
365 3KN5 ANP 0.000000006806 0.753 40
366 2WQN ADP 0.000008324 0.59474 40
367 3EKK GS2 0.00000269 0.51729 40.0651
368 4BFM ANP 0.000000003005 0.72122 40.1198
369 5USZ SKE 0.0000002891 0.59196 40.1384
370 5EKO N17 0.0001614 0.49344 40.2857
371 4G17 0VN 0.00004263 0.55189 40.303
372 3BU5 ATP 0.000000006168 0.72467 40.5229
373 3SXF BK5 0.00001445 0.49747 40.5714
374 3RI1 3RH 0.0000001049 0.61623 40.5751
375 3SXS PP2 0.000007169 0.56493 40.6716
376 4CSV STI 0.000189 0.49039 40.7273
377 3G5D 1N1 0.0000001324 0.49491 40.9091
378 4U0I 0LI 0.0001856 0.46484 40.9524
379 2X2M X2M 0.00000005109 0.65672 41.0828
380 3HZT J60 0.000000742 0.6575 41.1429
381 5VCV 1N1 0.0000001392 0.62349 41.1576
382 5UR1 YY9 0.0001153 0.44364 41.1576
383 4N70 2HX 0.0000000001502 0.61581 41.1585
384 4TWP AXI 0.00001442 0.4687 41.3284
385 5FBN 5WF 0.00001602 0.49577 41.6974
386 3SRV S19 0.000000001846 0.76003 41.8773
387 4F4P 0SB 0.0000002587 0.47441 42.4908
388 4I6H 1C8 0.0001392 0.51519 42.5325
389 1BYG STU 0.000000009683 0.73463 42.8058
390 5DEY 59T 0.00001311 0.44458 43.0976
391 3BZ3 YAM 0.00003212 0.42671 43.1159
392 3CY2 MB9 0.00000001404 0.6745 43.3121
393 2WEL K88 0.000003339 0.64892 43.4251
394 5DH3 5BS 0.000001591 0.59518 43.4921
395 2X4Z X4Z 0.000001311 0.53692 43.5811
396 5IH9 6BF 0.0000003809 0.5528 43.5821
397 5DRB 5FJ 0.0000331 0.45402 44.3299
398 1ZY5 ANP 0.0000001127 0.67234 44.8845
399 4L9I 8PR 0.00000001676 0.71298 45.7143
400 4A4X JUP 0.00002725 0.51408 46.2366
401 5A6N U7E 0.0000001712 0.44141 46.2898
402 5UOX 8GY 0.00000001279 0.68404 47.6015
403 2ZV2 609 0.00000002727 0.73273 47.9866
404 4WNK 453 0.00000000003666 0.73817 48.5714
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