-->
Receptor
PDB id Resolution Class Description Source Keywords
5IRC 1.72 Å EC: 3.-.-.- P190A GAP DOMAIN COMPLEX WITH RHOA RATTUS NORVEGICUS PROTEIN-PROTEIN COMPLEX TRANSITION STATE GTPASE GAP DOMAIPROTEIN BINDING
Ref.: DECIPHERING THE MOLECULAR AND FUNCTIONAL BASIS OF R FAMILY PROTEINS: A SYSTEMATIC APPROACH TOWARD SELEC INACTIVATION OF RHO FAMILY PROTEINS. J.BIOL.CHEM. V. 291 20353 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MGF D:203;
F:203;
Invalid;
Invalid;
none;
none;
submit data
81.3 F3 Mg F[Mg-...
GDP D:201;
F:201;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG D:202;
F:202;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
CL B:1501;
A:1502;
A:1501;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
35.453 Cl [Cl-]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5IRC 1.72 Å EC: 3.-.-.- P190A GAP DOMAIN COMPLEX WITH RHOA RATTUS NORVEGICUS PROTEIN-PROTEIN COMPLEX TRANSITION STATE GTPASE GAP DOMAIPROTEIN BINDING
Ref.: DECIPHERING THE MOLECULAR AND FUNCTIONAL BASIS OF R FAMILY PROTEINS: A SYSTEMATIC APPROACH TOWARD SELEC INACTIVATION OF RHO FAMILY PROTEINS. J.BIOL.CHEM. V. 291 20353 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5M70 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5M6X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1OW3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4XSG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 3LXR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 3LWN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 3LW8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4XOI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
9 6BCA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
10 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 6BC0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
13 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 1CXZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
15 4D0N - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 1HE1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5M70 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 5M6X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1OW3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 2WMO - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 2WMN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 2NGR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4XSG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
9 3LXR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 3LWN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 3LW8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 4XOI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
13 6BCA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
14 1E96 Kd = 2.7 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
15 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 6BC0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
18 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
19 1CXZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
20 4YC7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
21 4D0N - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found with APoc: 531
This union binding pocket(no: 1) in the query (biounit: 5irc.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 4PPF FLC 1.99005
2 3LRE ADP 2.48756
3 3UIE ANP 2.5
4 3ZS9 ADP ALF 2.68817
5 2WOJ ADP ALF 2.68817
6 5MZN ADP 2.68817
7 2ZR9 DTP 2.68817
8 5U32 GDP 2.98507
9 3IO3 ADP 2.98507
10 2NCD ADP 2.98507
11 1D2E GDP 3.22581
12 1QF5 GDP 3.22581
13 1QF5 RPL 3.22581
14 4V03 ADP 3.22581
15 3FB4 AP5 3.22581
16 3BFV ADP 3.22581
17 1W5T ANP 3.22581
18 5LLB 6YZ 3.22581
19 1W5T ADP 3.22581
20 3FWY ADP 3.48259
21 4ZNL BEF ADP 3.48259
22 1VKJ A3P 3.48259
23 3FYH ADP 3.48259
24 1G3M PCQ 3.48259
25 1G3M A3P 3.48259
26 5M04 GDP 3.76344
27 5ZB0 TYD 3.76344
28 5ZB0 ADP 3.76344
29 5G41 AP5 3.76344
30 1JJV ATP 3.76344
31 1D2N ANP 3.76344
32 1TE2 PGA 3.76344
33 2O0J ADP 3.76344
34 1V8K ANP 3.9801
35 1T5C ADP 3.9801
36 2ZFI ADP 3.9801
37 2GKS ADP 3.9801
38 4YDS ATP 3.9801
39 1VHT BA3 3.9801
40 2HCJ GDP 4.30108
41 2FH5 GTP 4.30108
42 5JBQ GDP 4.30108
43 5W7Q GDP 4.30108
44 1D8T GDP 4.30108
45 2BVN GNP 4.30108
46 5FHD ADP ALF 4.30108
47 1X6V ADP 4.30108
48 5ZBR ANP 4.30108
49 5FTB ANP 4.30108
50 3Q9L ATP 4.30108
51 3P4X ADP 4.30108
52 1ION ADP 4.30108
53 1G3Q ADP 4.30108
54 1AKY AP5 4.30108
55 2GK6 ADP 4.30108
56 1OFU GDP 4.30108
57 5UIV ADP 4.40529
58 5W75 GDP 4.47761
59 1YTM ATP 4.47761
60 5K5Z ANP 4.47761
61 2ZTS ADP 4.47761
62 1JI0 ATP 4.47761
63 4QM7 GTP 4.67836
64 5BQ5 ADP BEF 4.7619
65 2C78 GNP 4.83871
66 2C77 GNP 4.83871
67 4CVN ADP 4.83871
68 4PFO ADP 4.83871
69 5L3W GDP 4.83871
70 1GOJ ADP 4.83871
71 3DZD ADP 4.83871
72 3BOS CDP 4.83871
73 3TMK T5A 4.83871
74 1IN4 ADP 4.83871
75 1G6H ADP 4.83871
76 5L3S GNP 4.97512
77 5L3V GDP 4.97512
78 1F9V ADP 4.97512
79 3H4S ADP 4.97512
80 4FRZ ADP 4.97512
81 1NJF AGS 4.97512
82 4TTQ ATP 4.97512
83 5G3Y ADP 4.97512
84 1NJF ADP 4.97512
85 5EXT ADP 5
86 2WJG GDP 5.31915
87 5KUT GDP 5.37634
88 1SKQ GDP 5.37634
89 4NON GDP 5.37634
90 1G7S GDP 5.37634
91 3ZFD ANP 5.37634
92 1IHU ADP 5.37634
93 1IHU AF3 5.37634
94 1SQ5 ADP 5.37634
95 3FVQ ATP 5.37634
96 2CBZ ATP 5.37634
97 4R2I ANP 5.37634
98 5ZXD ATP 5.37634
99 3NHB ADP 5.37634
100 4XGU ADP 5.37634
101 2DPY ADP 5.37634
102 4E03 ADP 5.47264
103 5H68 AGS 5.47264
104 4MKF AP5 5.47264
105 4FCW ADP 5.47264
106 3KJI ADP 5.47264
107 4P3Y GDP 5.49451
108 1XPJ TLA 5.55556
109 1W4R TTP 5.64103
110 4P4T GDP 5.91398
111 4NE2 SH2 5.91398
112 4NE2 ADP 5.91398
113 5I0H ADP BEF 5.91398
114 1XMV ADP 5.91398
115 5X40 ACP 5.91398
116 1SVM ATP 5.91398
117 4MKG AP5 5.91398
118 2CDN ADP 5.91398
119 1FNN ADP 5.91398
120 4ZKD GDP 5.97015
121 5N69 ADP 5.97015
122 5BN3 ADP 5.97015
123 3EZ2 ADP 5.97015
124 2XAU ADP 5.97015
125 2OG2 MLI 5.97015
126 3B9Q MLI 5.97015
127 2WJH GDP 6.0241
128 2WJH FLC 6.0241
129 5W76 GDP 6.45161
130 2Y65 ADP 6.45161
131 3COB ADP 6.45161
132 4H1V GNP 6.45161
133 4QOS ADP 6.45161
134 1RRC ADP 6.45161
135 4PJ3 ANP 6.45161
136 4LJ9 ACP 6.45161
137 4ZDJ UTP 6.45161
138 1KK8 BEF ADP 6.46766
139 1B7T ADP 6.46766
140 4R43 GDP 6.46766
141 2FNA ADP 6.46766
142 1DAK ADP 6.46766
143 1DAK DPU 6.46766
144 4PX9 ADP 6.46766
145 6B8B ADP 6.46766
146 2CHG ANP 6.46766
147 4BQS ADP 6.81818
148 4BQS K2Q 6.81818
149 4PC3 GDP 6.96517
150 1LVK MNT BEF 6.96517
151 3E70 GDP 6.96517
152 2WHX ADP 6.98925
153 5VHC BEF ADP 6.98925
154 2OFW ADX 6.98925
155 4JLV ADP 6.98925
156 2JLR ANP 6.98925
157 4D81 ADP 6.98925
158 1OS1 PYR 6.98925
159 1OS1 ATP 6.98925
160 4OHY ANP 6.98925
161 2RGX AP5 6.98925
162 5TIV A3P 6.98925
163 2YOH WMJ 6.98925
164 1XKV ATP 6.98925
165 4A4Z ANP 6.98925
166 3QVV 3QV 6.98925
167 3QVV A3P 6.98925
168 5XKT GNP 7
169 2QQ0 ANP 7.06522
170 2QQ0 THM 7.06522
171 1LVG ADP 7.07071
172 2PEZ GGZ 7.26257
173 2PEZ DAT 7.26257
174 5MVR ADP 7.40741
175 1YRB GDP 7.46269
176 2XT3 ADP 7.46269
177 4R98 GNH 7.46269
178 3ZQ6 ADP ALF 7.46269
179 5VGR GDP 7.46269
180 3U6B GDP 7.52688
181 3U6K GDP 7.52688
182 4G5G GDP 7.52688
183 3T34 GDP 7.52688
184 4Q1A 2XZ 7.52688
185 4Q1A UDP 7.52688
186 4XVU ATP 7.52688
187 4LYA ATP 7.52688
188 2FAH GDP 7.52688
189 1ZIN AP5 7.52688
190 1NHX FTB 7.52688
191 1NHX PEP 7.52688
192 2GMV UN8 7.52688
193 5L3R GCP 7.52688
194 2GMV PEP 7.52688
195 2Z5F A3P 7.52688
196 2RHO GSP 7.52688
197 1U0J ADP 7.52688
198 2BEK ATP 7.9602
199 2OZE AGS 7.9602
200 5M7P ADP 7.9602
201 2CE7 ADP 7.9602
202 1W5F G2P 7.9602
203 4DCT GDP 8.06452
204 3CNL GNP 8.06452
205 1IWE IMP 8.06452
206 2QG6 NMN 8.06452
207 2B8T THM 8.06452
208 2W58 ADP 8.45771
209 4NU0 AP5 8.45771
210 3DKP ADP 8.45771
211 4IEE AGS 8.45771
212 4YJ1 ADP 8.45771
213 4QRH 0O2 8.45771
214 4IV9 FAD 8.45771
215 5Y6N ADP 8.60215
216 1OXV ANP 8.60215
217 1PG4 PRX 8.60215
218 1PG4 COA 8.60215
219 1WDT GTP 8.95522
220 1OFH ADP 8.95522
221 1NN5 2DT 8.95522
222 1NN5 ANP 8.95522
223 1UJ2 ADP 8.95522
224 1UJ2 C5P 8.95522
225 2FSH ANP 8.95522
226 4YMU ATP 8.95522
227 4GBM A3P 8.95522
228 6FAA ADP 8.95522
229 4LPS GDP 9.13978
230 5H7K GDP 9.13978
231 4U00 ADP 9.13978
232 1M7G AV2 9.13978
233 1M7G ADX 9.13978
234 1M7G ADP 9.13978
235 1FP6 ADP 9.13978
236 1S3G AP5 9.13978
237 1Z83 AP5 9.13978
238 2PL3 ADP 9.13978
239 4WEI GLC GAL 9.13978
240 4GID 0GH 9.13978
241 2GWH A3P 9.13978
242 3PQC GDP 9.23077
243 5IRR GSP 9.45274
244 4YS0 ADP 9.45274
245 3EWA ANP 9.45274
246 4RD0 GDP 9.67742
247 5I34 GDP 9.67742
248 6A20 ADP 9.67742
249 1Z6T ADP 9.67742
250 4IHQ ADP 9.95025
251 1E2K TMC 9.95025
252 3QXC ATP 9.95025
253 4WZA ADP 10.2151
254 4WZA ACP 10.2151
255 3B5J 12D 10.2151
256 5TSH ANP 10.2151
257 5TSH ADP 10.2151
258 5GVR LMR 10.2151
259 1P72 ADP 10.2151
260 1NY5 ADP 10.2151
261 3B7G ANP 10.2151
262 2C9O ADP 10.2151
263 5J1J ANP 10.2151
264 1X8J A3P 10.2151
265 1W7J ADP BEF 10.4478
266 1K6M AGS 10.4478
267 6FP4 FAD 10.4478
268 2ZPA ADP 10.4478
269 1XX6 ADP 10.4712
270 4X8O AP5 10.7527
271 3DC4 ADP 10.7527
272 2JAQ DCP 10.7527
273 2ZE7 DST 10.7527
274 4XTR ATP 10.8108
275 4XTR ADP 10.8108
276 2HF9 GSP 10.9453
277 1G41 ADP 10.9453
278 3WYA GDP 11.2903
279 3WY9 GDP 11.2903
280 2PZE ATP 11.2903
281 1R0X ATP 11.2903
282 1OYY AGS 11.2903
283 4XTX 590 11.2903
284 4GOX A3P 11.4428
285 5XDR ADP 11.4428
286 1TQ4 GDP 11.828
287 1F5N GNP 11.828
288 1L2T ATP 11.828
289 2Q2Y MKR 11.828
290 2Q2Y ADP 11.828
291 5IFS ADP 11.828
292 5H7J GCP 11.9403
293 4ZG4 VO4 ADP 11.9403
294 2BIF SIN 11.9403
295 2BIF ANP 11.9403
296 2QZ4 ADP 11.9403
297 1OE0 TTP 11.9403
298 1G7C 5GP 12.3656
299 5HR5 ADP 12.3656
300 5J1S ATP 12.3656
301 1JJ7 ADP 12.3656
302 3TBK ANP 12.3656
303 1B0U ATP 12.3656
304 2WIC GNP 12.4378
305 1H65 GDP 12.4378
306 1W0J ADP 12.4378
307 1W0J ADP BEF 12.4378
308 4BFW ZVW 12.4378
309 4RZ3 ADP 12.4378
310 6B4K ANP 12.4378
311 4WOP CTP 12.4444
312 1P9B GDP 12.9032
313 2ZPT A3P 12.9032
314 2VVG ADP 12.9353
315 3BFX A3P 12.9353
316 2WZF BGC 12.9353
317 3TK1 GDP 13.4328
318 2BO4 FLC 13.4328
319 3FKQ ATP 13.4409
320 1KO8 6PG 13.7143
321 3IIJ ADP 13.8889
322 1UKZ ADP 13.9303
323 1XEX ATP 13.9535
324 3RLF ANP 13.9785
325 4TL6 ANP 13.9785
326 4WZ6 ATP 13.9785
327 2AWN ADP 13.9785
328 1AQU A3P 13.9785
329 2KIN ADP 14
330 3QKT ANP 14.4279
331 5YT0 GDP 14.5161
332 5FG3 GDP 14.5161
333 5GOE GDP 14.5161
334 1DAR GDP 14.5161
335 1WY7 SAH 14.5161
336 3VMF GTP 14.9254
337 3WXM GTP 14.9254
338 5WC2 ADP 14.9254
339 2IS6 ADP 14.9254
340 1QF9 ALF 14.9485
341 1QF9 ADP 14.9485
342 1QF9 C5P 14.9485
343 4KVA GTP 15.0538
344 3ITJ CIT 15.0538
345 5CK5 GDP 15.5914
346 3DEF GDP 15.5914
347 5KMS FAD 15.5914
348 3KTA AP5 15.6069
349 5BYK A3P 15.8301
350 5BYK OAQ 15.8301
351 2XTZ GSP 16.129
352 1CR1 TTP 16.129
353 1XP8 AGS 16.129
354 1KK1 GNP 16.6667
355 3CX8 GSP 16.6667
356 1BH2 GSP 16.6667
357 2ODE ALF GDP 16.6667
358 3AB3 GDP 16.6667
359 1Y3A GDP 16.6667
360 4BAS GNP 16.6667
361 6CRK GDP 16.6667
362 2OM2 GDP 16.6667
363 1ZCB GDP 16.6667
364 1SVK ALF GDP 16.6667
365 5Z69 AGS 16.6667
366 1BG2 ADP 16.9154
367 1MKY GDP 17.2043
368 2VB6 ADP BEF 17.4497
369 1GXU 2HP 17.5824
370 4J0Q GDP 17.7419
371 2V7Q ATP 17.8082
372 2CK3 ANP 17.8082
373 2V7Q ADP 17.8082
374 2CK3 ADP 17.8082
375 2QN6 GDP 18.2796
376 3W5J GDP 18.8172
377 1HTW ADP 18.9873
378 3ZIA ADP 19.0476
379 3ZIA ATP 19.0476
380 2IYL GDP 19.3662
381 3A1S GDP 19.403
382 1F2U ATP 19.5946
383 5AK0 8V1 19.9005
384 1NRJ GTP 20.2532
385 1CS4 GSP 20.4301
386 4IDN GNP 20.4301
387 6AU6 GDP 20.9677
388 3A4M ADP 20.9677
389 2X77 GDP 21.6931
390 1YZG GDP 21.7877
391 5LTJ ADP 21.8905
392 5LTJ BEF 21.8905
393 4OI4 ATP 21.8905
394 1ZJ6 G3D 22.043
395 1PUJ GNP 22.3881
396 6CS8 F9Y 22.5806
397 2A5F GTP 22.8571
398 1ZUI SKM 22.8856
399 5KDO GDP 22.973
400 1RJ9 GCP 23.1183
401 5IRN ADP 23.1183
402 4AUT FAD 23.8806
403 5EE5 GTP 23.9766
404 3PCR GTP 24.0741
405 4M9Q GNP 24.2291
406 1MR3 G3D 24.3094
407 2OBM ADP 24.3781
408 3N5C GDP 24.6914
409 4NCN GTP 24.7312
410 4TMZ GSP 24.7312
411 6C90 ADP 25
412 2D7D ADP 25
413 1Y63 ADP 25.5435
414 5LB3 ADP 27.3632
415 5KSP GDP 27.4194
416 5KSZ GCP 27.957
417 2RCN GDP 27.957
418 3DOE GTP 27.957
419 1F6B GDP 27.957
420 1UPT GTP 28.3333
421 3H86 AP5 28.6458
422 5HCN GCP 29.5699
423 3QF7 ANP 30
424 4KAX GTP 30.1775
425 4HI0 GDP 30.3483
426 5DI3 GNP 31.3514
427 1R4A GNP 31.3725
428 1KSH GDP 31.7204
429 2W83 GTP 32.1212
430 3AQ4 GDP 32.6087
431 1FQJ ALF 32.7957
432 1FQJ GDP 32.7957
433 3T12 GDP ALF 33.3333
434 3T1O GDP 33.3333
435 4HSE ADP 33.3333
436 4YLG GDP 34.104
437 2ZEJ GDP 34.7826
438 1ZD9 GDP 34.9462
439 4V0K GDP 35.503
440 1J2J GTP 36.1446
441 2J59 GTP 36.1446
442 1O3Y GTP 36.1446
443 3GJ4 GDP 36.5591
444 3GJ7 GDP 36.5591
445 3GJ5 GDP 36.5591
446 3GJ8 GDP 36.5591
447 3GJX GTP 36.5591
448 5DIF GNP 37.0968
449 5UWU GNP 37.0968
450 5UWJ GNP 37.0968
451 5UWO GNP 37.0968
452 5UWI GNP 37.0968
453 5UWQ GNP 37.0968
454 5UWP GNP 37.0968
455 5UWT GNP 37.0968
456 5UWR GNP 37.0968
457 5DHF GNP 37.0968
458 6CIT GNP 37.0968
459 4HAT GNP 37.0968
460 5UWW GNP 37.0968
461 5UWH GNP 37.0968
462 5UWS GNP 37.0968
463 3CH5 GDP 37.0968
464 3GJ3 GDP 37.0968
465 5DI9 GNP 37.0968
466 1M2O GNP 37.0968
467 1RE0 GDP 37.1951
468 1S9D GDP 37.1951
469 3M1I GTP 37.6344
470 3WYF GTP 37.6344
471 4B47 GDP 37.6344
472 5OEC GDP 38.2514
473 3WYG GTP 38.4615
474 1Z06 GNP 38.7097
475 1WA5 GTP 39.2045
476 2QTV GNP 41.3174
477 3BC1 GNP 41.3979
478 3CPJ GDP 41.3979
479 2CJW GDP 41.3979
480 3Q72 GNP 42.1687
481 2BME GNP 43.5484
482 1FZQ GDP 43.6464
483 3RWO GDP 43.7838
484 1YZN GNP 43.7838
485 3E5H GNP 43.8202
486 4GOJ GNP 43.9153
487 1OIX GDP 44.086
488 2BCG GDP 44.086
489 2HT6 GDP 44.2529
490 1OIV GDP 44.6237
491 2A5J GDP 44.6237
492 4ZI2 GNP 44.7368
493 1X1R GDP 44.9438
494 3TKL GTP 45.1613
495 5SZH GNP 45.1613
496 2F9L GDP 45.1613
497 1Z0F GDP 45.2514
498 1Z0K GTP 45.3488
499 3Q85 GNP 45.5621
500 4D0G GTP 45.7143
501 5O74 GDP 46.1111
502 5JCZ GDP 46.3687
503 5UQW GDP 46.5608
504 4LX0 BEF GDP 46.8927
505 3SFV GDP 46.9613
506 2A9K GDP 47.0588
507 1EK0 GNP 47.0588
508 5OCG GNP 47.3118
509 1VG0 GDP 47.3118
510 1VG8 GNP 47.3118
511 3NKV GNP 47.4286
512 3T5G GDP 47.5138
513 1VG1 GDP 47.5676
514 1VG9 GDP 47.5676
515 4DKX GDP 47.8495
516 1TU3 GNP 47.9532
517 4C4P GNP 47.9769
518 5TB5 GDP 48.1081
519 5TAR GDP 48.1081
520 1D5C GDP 48.1481
521 3MJH GTP 48.2143
522 1R2Q GNP 48.2353
523 6BSX GDP 48.3146
524 6BSX E7S 48.3146
525 1KY3 GDP 48.3517
526 1ZC3 GNP 48.5714
527 1UAD GNP 49.1429
528 5Z2M GTP 49.4318
529 5LEF GTP 49.4624
530 1KAO GDP 49.7006
531 1YVD GNP 49.7041
Pocket No.: 2; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found with APoc: 7
This union binding pocket(no: 2) in the query (biounit: 5irc.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 2QQ0 TMP 7.06522
2 2QQ0 ADP 7.06522
3 2ORV 4TA 8.60215
4 2ZE7 AMP 10.7527
5 1Q20 PLO 12.3656
6 1Q20 A3P 12.3656
7 4U60 SIA GAL NGA 18.2796
Pocket No.: 3; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found with APoc: 1
This union binding pocket(no: 3) in the query (biounit: 5irc.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 3A5Z KAA 8.95522
Pocket No.: 4; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5irc.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback