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Receptor
PDB id Resolution Class Description Source Keywords
5IDM 1.9 Å EC: 2.-.-.- BIFUNCTIONAL HISTIDINE KINASE CCKA (DOMAIN, CA) IN COMPLEX W GMP AND AMPPNP/MG2+ CAULOBACTER VIBRIOIDES BIFUNCTIONAL HISTIDINE KINASE PHOSPHATASE TRANSFERASE
Ref.: CYCLIC DI-GMP MEDIATES A HISTIDINE KINASE/PHOSPHATA BY NONCOVALENT DOMAIN CROSS-LINKING. SCI ADV V. 2 00823 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:602;
B:601;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP A:601;
B:600;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
C2E A:603;
Valid;
none;
submit data
690.411 C20 H24 N10 O14 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5IDM 1.9 Å EC: 2.-.-.- BIFUNCTIONAL HISTIDINE KINASE CCKA (DOMAIN, CA) IN COMPLEX W GMP AND AMPPNP/MG2+ CAULOBACTER VIBRIOIDES BIFUNCTIONAL HISTIDINE KINASE PHOSPHATASE TRANSFERASE
Ref.: CYCLIC DI-GMP MEDIATES A HISTIDINE KINASE/PHOSPHATA BY NONCOVALENT DOMAIN CROSS-LINKING. SCI ADV V. 2 00823 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5IDM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 5IDM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5IDM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Ligand no: 2; Ligand: C2E; Similar ligands found: 57
No: Ligand ECFP6 Tc MDL keys Tc
1 35G 1 0.986111
2 C2E 1 1
3 PCG 1 0.986111
4 4BW 0.806818 1
5 1YD 0.806818 1
6 5GP 5GP 0.743902 0.958904
7 4UR 0.731959 1
8 6SW 0.627907 0.944444
9 1YC 0.616162 0.972222
10 6J7 0.58427 0.934211
11 CMP 0.534091 0.902778
12 2BA 0.534091 0.916667
13 GMP 0.53012 0.828947
14 1SY 0.495575 1
15 SGP 0.483871 0.825
16 6SZ 0.483871 0.916667
17 3GP 0.478261 0.92
18 1OR 0.474747 0.741176
19 G 0.468085 0.933333
20 5GP 0.468085 0.933333
21 7CH 0.467391 0.888889
22 6SX 0.462366 0.861111
23 6JR 0.457944 0.944444
24 G2R 0.457143 0.886076
25 GPX 0.451923 0.894737
26 GP3 0.44898 0.947368
27 2GP 0.446809 0.907895
28 GP2 0.444444 0.886076
29 GDP 0.444444 0.921053
30 GNH 0.44 0.909091
31 P2G 0.4375 0.881579
32 G2P 0.436893 0.886076
33 GMV 0.431373 0.897436
34 GTP 0.431373 0.921053
35 ALF 5GP 0.431373 0.841463
36 G1R 0.427184 0.909091
37 GCP 0.427184 0.897436
38 G3D 0.423077 0.933333
39 9GM 0.423077 0.897436
40 GSP 0.423077 0.875
41 GNP 0.423077 0.897436
42 GDP AF3 0.420561 0.841463
43 G4P 0.415094 0.933333
44 GAV 0.415094 0.886076
45 P1G 0.414141 0.87013
46 Y9Z 0.410714 0.833333
47 GCP G 0.409091 0.894737
48 GDP ALF 0.407407 0.841463
49 ALF GDP 0.407407 0.841463
50 N6R 0.40708 0.831169
51 N6S 0.40708 0.831169
52 G G 0.40708 0.947368
53 G3A 0.403509 0.947368
54 YGP 0.401786 0.876543
55 GPG 0.4 0.935065
56 G5P 0.4 0.947368
57 0O2 0.4 0.933333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5IDM; Ligand: ANP; Similar sites found with APoc: 138
This union binding pocket(no: 1) in the query (biounit: 5idm.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 2JDU MFU None
2 1UQX MMA None
3 2BOS GLA GAL GLC None
4 1HBK MYR None
5 2BOS GLA GAL GLC NBU None
6 4L8F MTX 1.11732
7 1L7N AF3 2.23464
8 3C2O NTM 2.23464
9 5Z49 RUB 2.23464
10 1BGQ RDC 2.7933
11 4XFR CIT 2.7933
12 2AJH MET 2.7933
13 4PLG NAI 2.7933
14 4PLG OXM 2.7933
15 4KFU ACP 2.7933
16 2AWN ADP 2.7933
17 5I8F ML1 3.0303
18 5UC4 83S 3.35196
19 3EHH ADP 3.35196
20 2BGS NDP 3.35196
21 1SO0 GAL 3.35196
22 4P83 U5P 3.35196
23 1TV5 N8E 3.35196
24 4YKG FAD 3.35196
25 4WOH 4NP 3.61446
26 1YC4 43P 3.91061
27 4EMV 0R9 3.91061
28 5GVR LMR 3.91061
29 1JXZ BCA 3.91061
30 1NZY BCA 3.91061
31 1OX5 1PR 3.91061
32 5A4W QCT 3.91061
33 5YB7 FAD 3.91061
34 1YUM NCN 4.13223
35 2JHP GUN 4.46927
36 6FU4 HSM 4.46927
37 2WR9 MAN MAN 4.6875
38 4LFL TG6 4.93827
39 4XCL AGS 5.02793
40 3H4L ANP 5.02793
41 3K60 ADP 5.02793
42 4B7P 9UN 5.02793
43 2YI0 YI0 5.02793
44 4ZVI 4S4 5.02793
45 1KZN CBN 5.02793
46 6HH6 A3R 5.02793
47 3K7S R52 5.02793
48 4V03 ADP 5.02793
49 2PS1 ORO 5.02793
50 3B12 FAH 5.02793
51 4UTG ANP 5.02793
52 5V6F MAN BMA MAN 5.07246
53 1GKZ ADP 5.58659
54 1ZXM ANP 5.58659
55 5O4J 9KH 5.58659
56 5O4J SAH 5.58659
57 5O4J PJL 5.58659
58 4BVA T3 5.58659
59 4FHT DHB 5.73248
60 1MAI I3P 6.10687
61 1S16 ANP 6.14525
62 1S14 NOV 6.14525
63 4HZ0 1AV 6.14525
64 1KIJ NOV 6.14525
65 5LXT GTP 6.14525
66 4O08 PO6 6.14525
67 6CB2 OLC 6.14525
68 5WBF LAC 6.14525
69 2VZZ SCA 6.14525
70 1HQS CIT 6.14525
71 1QZR CDX 6.70391
72 5F5R ANP 6.70391
73 5OF9 ANP 6.70391
74 1QZR ANP 6.70391
75 4GGL CJC 6.70391
76 4HY1 19X 6.70391
77 4L2H AR6 AR6 6.70391
78 1H82 GZZ 6.70391
79 1H82 FAD 6.70391
80 3QPB URA 6.70391
81 1O5O U5P 6.78733
82 4XCP PLM 7.05882
83 1B63 ANP 7.26257
84 4DE3 DN8 7.26257
85 4WEI GLC GAL 7.26257
86 4BAE RWX 7.82123
87 4B6C B5U 7.82123
88 6EL3 NAP 7.82123
89 5V3D FCN 8.27586
90 5Y3N 8MF 8.37989
91 5AHO TLA 8.37989
92 1H74 ADP 8.37989
93 4TV1 36M 8.37989
94 1EKO I84 8.37989
95 1EKO NAP 8.37989
96 4P8O 883 8.93855
97 3TTZ 07N 8.93855
98 4IPE ANP 9.49721
99 4IVG ANP 9.49721
100 4URN NOV 9.49721
101 4URL XAM 9.49721
102 4WGF HX2 10.0559
103 4IF4 BEF 10.0559
104 2O1V ADP 10.6145
105 6D28 NEC 10.6145
106 2GFD RDA 10.6145
107 1HYH NAD 10.6145
108 3F81 STT 10.6145
109 2BOI MFU 10.6195
110 1OYF MHN 10.7438
111 5NM7 GLY 11.1732
112 1Q19 SSC 11.1732
113 6BYF CIT 11.1765
114 4V1F BQ1 11.6279
115 3EHG ATP 11.7188
116 2HGS GSH 11.7318
117 2CB8 MYA 12.6437
118 3GGU 017 14.1414
119 5J6A P46 15.0838
120 1Y8O ADP 15.6425
121 3IT7 TLA 16.7598
122 1ID0 ANP 17.1053
123 2GAG NAD 17.1429
124 2HKJ RDC 17.3184
125 2OG2 MLI 18.4358
126 1GTE FAD 19.5531
127 1NF8 BOG 20.1117
128 1TID ATP 20.5882
129 2ZKJ ADP 20.6704
130 2XCM ADP 21.6216
131 1TH8 ADP 24.1379
132 1I58 ACP 24.581
133 1I58 ADP 24.581
134 2IOR ADP 25.1397
135 4BIX ADP 29.0503
136 3D36 ADP 36.3129
137 4PL9 ADP 36.612
138 4GCZ ADP 43.0168
Pocket No.: 2; Query (leader) PDB : 5IDM; Ligand: C2E; Similar sites found with APoc: 29
This union binding pocket(no: 2) in the query (biounit: 5idm.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
1 5X68 FAD 2.23464
2 2ZFZ ARG 2.53165
3 5YJS SAL 3.91061
4 3EFS BTN 3.91061
5 1WXI AMP 3.91061
6 5TS5 FAD 3.91061
7 4USQ FAD 3.91061
8 4EIP FAD 4.46927
9 5VN0 FAD 4.46927
10 1IH7 GMP 5.58659
11 4NTD FAD 5.58659
12 5BVA FAD 5.58659
13 1G27 BB1 6.54762
14 4JNA FAD 7.26257
15 1NAA ABL 7.82123
16 1NAA 6FA 7.82123
17 2OKL BB2 7.82123
18 1QO8 FAD 7.82123
19 3IHG FAD 8.37989
20 2DXU BT5 8.37989
21 3K7M FAD 9.49721
22 2RGO FAD 10.0559
23 1LQY BB2 10.6145
24 3M6P BB2 12.8492
25 3ICT FAD 14.5251
26 3ICS FAD 14.5251
27 3ICR FAD 14.5251
28 2DKH 3HB 15.0838
29 2DKH FAD 15.0838
Pocket No.: 3; Query (leader) PDB : 5IDM; Ligand: ANP; Similar sites found with APoc: 67
This union binding pocket(no: 3) in the query (biounit: 5idm.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1TUK PGM None
2 2PKA BEN 1.31579
3 1L7N ALF 2.23464
4 2ZFZ ARG 2.53165
5 4V15 PLP 2.7933
6 1NJJ GET 2.7933
7 3IWJ NAD 2.7933
8 4JZ8 CIT 3.35196
9 1T3D CYS 3.35196
10 4IHL 1F5 3.35196
11 5ZI9 FLC 3.35196
12 4YKG NAD 3.35196
13 4X1Z FUC GAL NDG 3.91061
14 4AP3 NAP 3.91061
15 4AP3 FAD 3.91061
16 2IID PHE 3.91061
17 2IID FAD 3.91061
18 4RPL FAD 3.91061
19 4RPL 3UC 3.91061
20 4FWE FAD 3.91061
21 5ZRR 9J3 3.91061
22 5TS5 FAD 3.91061
23 1C3M MAN MAN 4.08163
24 3LN9 FLC 4.31655
25 1V0C ACO 4.46927
26 1V0C KNC 4.46927
27 2DT9 THR 4.46927
28 4G2R H1L 4.46927
29 5O22 C3R 4.46927
30 1REO FAD 4.46927
31 2BES RES 4.65116
32 4GUS FAD 5.02793
33 4HSU FAD 5.02793
34 4GUT FAD 5.02793
35 5U8U FAD 5.58659
36 5MIT NAP 6.14525
37 5MIT FAD 6.14525
38 4AF5 CIT 6.14525
39 3F8D FAD 6.14525
40 1PS9 FAD 6.14525
41 4G9N NGA 6.29371
42 5XQL C2E 6.70391
43 3QPB R1P 6.70391
44 4DDY DN6 7.26257
45 3NB0 G6P 7.26257
46 2FZW NAD 7.82123
47 4IV9 TSR 8.37989
48 2C7G FAD 8.93855
49 5J5Z FAD 8.93855
50 2C7G ODP 8.93855
51 3H2K BOG 9.49721
52 3G4Q MCH 9.58904
53 5G3U ITW 10.0559
54 5G3U FDA 10.0559
55 5ZBC FAD 10.0559
56 5G5G MCN 10.0559
57 3I6B KDO 10.0559
58 6F5W KG1 10.6145
59 3OQJ 3CX 11.284
60 1ZK7 FAD 11.7318
61 2YG3 FAD 12.8492
62 3X0V FAD 12.8492
63 2J5V PCA 14.5251
64 2GAG FOA 17.1429
65 1VCO GLN 17.8771
66 5YV5 ADP 18.4358
67 3KP6 SAL 21.1921
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