Receptor
PDB id Resolution Class Description Source Keywords
5ICV 1.53 Å EC: 2.3.1.48 CRYSTAL STRUCTURE OF HUMAN NATF (HNAA60) BOUND TO A BISUBSTR ANALOGUE HOMO SAPIENS TRANSFERASE ACETYLATION GNAT NAT
Ref.: CRYSTAL STRUCTURE OF THE GOLGI-ASSOCIATED HUMAN N ALPHA-ACETYLTRANSFERASE 60 REVEALS THE MOLECULAR DETERMINANTS FOR SUBSTRATE-SPECIFIC ACETYLATION. STRUCTURE V. 24 1044 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MET LYS ALA VAL 1XE C:1;
D:1;
 Valid;
Valid;
 Atoms found LESS than expected: % Diff = 0.012;
Atoms found LESS than expected: % Diff = 0.012;
 ic50 = 2.44 uM
1235.13 n/a S(CC(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5ICV 1.53 Å EC: 2.3.1.48 CRYSTAL STRUCTURE OF HUMAN NATF (HNAA60) BOUND TO A BISUBSTR ANALOGUE HOMO SAPIENS TRANSFERASE ACETYLATION GNAT NAT
Ref.: CRYSTAL STRUCTURE OF THE GOLGI-ASSOCIATED HUMAN N ALPHA-ACETYLTRANSFERASE 60 REVEALS THE MOLECULAR DETERMINANTS FOR SUBSTRATE-SPECIFIC ACETYLATION. STRUCTURE V. 24 1044 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 64 families.
1 5ICV ic50 = 2.44 uM MET LYS ALA VAL 1XE n/a n/a
2 5ICW - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 5ICV ic50 = 2.44 uM MET LYS ALA VAL 1XE n/a n/a
2 5ICW - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
3 5HGZ - MLA C3 H4 O4 C(C(=O)O)C....
4 5HH0 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
5 5HH1 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 25 families.
1 5ICV ic50 = 2.44 uM MET LYS ALA VAL 1XE n/a n/a
2 5ICW - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
3 5HGZ - MLA C3 H4 O4 C(C(=O)O)C....
4 5HH0 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
5 5HH1 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: MET LYS ALA VAL 1XE; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 MET LYS ALA VAL 1XE 1 1
2 MET VAL ASN ALA CMC 0.431111 0.966667
3 ACE SER ASP ALY THR NH2 COA 0.414847 0.923913
4 ACE MET LEU GLY PRO NH2 COA 0.413502 0.966667
5 ASP ASP ASP ILE NH2 CMC 0.404545 0.923913
Similar Ligands (3D)
Ligand no: 1; Ligand: MET LYS ALA VAL 1XE; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback