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Receptor
PDB id Resolution Class Description Source Keywords
5HR5 1.82 Å EC: 2.7.1.105 BOVINE HEART 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPH (PFKFB2) BOS TAURUS BOVINE PFKFB2 HYDROLASE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF HEART 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATAS (PFKFB2) AND THE INHIBITORY INFLUENCE OF CITRATE ON SUBSTRATE BINDING. PROTEINS V. 85 117 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DIO A:601;
Invalid;
none;
submit data
88.105 C4 H8 O2 C1COC...
F6P A:602;
Valid;
none;
submit data
260.136 C6 H13 O9 P C([C@...
ADP A:604;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
FLC A:603;
Valid;
none;
Ki = 80 uM
189.1 C6 H5 O7 C(C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HR5 1.82 Å EC: 2.7.1.105 BOVINE HEART 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPH (PFKFB2) BOS TAURUS BOVINE PFKFB2 HYDROLASE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF HEART 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATAS (PFKFB2) AND THE INHIBITORY INFLUENCE OF CITRATE ON SUBSTRATE BINDING. PROTEINS V. 85 117 2017
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5HR5 Ki = 80 uM FLC C6 H5 O7 C(C(=O)[O-....
2 5HTK Kd = 80 uM FLC C6 H5 O7 C(C(=O)[O-....
70% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1BIF - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
2 3BIF - SIN C4 H6 O4 C(CC(=O)O)....
3 2BIF - BOG C14 H28 O6 CCCCCCCCO[....
4 1K6M - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 2DWO Ki = 8.3 uM PEP C3 H5 O6 P C=C(C(=O)O....
6 2AXN - F6P C6 H13 O9 P C([C@@H]1[....
7 6HVH ic50 = 0.047 uM GV2 C28 H26 N6 O2 Cn1ccc2c1c....
8 5AJY ic50 = 0.496 uM 87T C20 H19 N5 O2 Cn1cc(cn1)....
9 3QPV - F6P C6 H13 O9 P C([C@@H]1[....
10 6HVI ic50 = 0.38 uM GV5 C22 H21 N5 O2 S CN(C)c1ccc....
11 5AK0 ic50 = 0.021 uM 8V1 C24 H25 N5 O2 Cn1cc(c2c1....
12 2I1V - F6P C6 H13 O9 P C([C@@H]1[....
13 4MA4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
14 5AJW ic50 = 0.104 uM S6L C24 H21 N5 O2 c1ccc(cc1)....
15 3QPW - PEP C3 H5 O6 P C=C(C(=O)O....
16 5AJZ ic50 = 0.343 uM MJP C17 H14 N4 O2 c1cc(ccc1N....
17 6HVJ ic50 = 0.028 uM GV8 C23 H18 N4 O3 S Cc1coc2c1c....
18 5HR5 Ki = 80 uM FLC C6 H5 O7 C(C(=O)[O-....
19 5HTK Kd = 80 uM FLC C6 H5 O7 C(C(=O)[O-....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1BIF - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
2 3BIF - SIN C4 H6 O4 C(CC(=O)O)....
3 2BIF - BOG C14 H28 O6 CCCCCCCCO[....
4 1K6M - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 2DWO Ki = 8.3 uM PEP C3 H5 O6 P C=C(C(=O)O....
6 2AXN - F6P C6 H13 O9 P C([C@@H]1[....
7 6HVH ic50 = 0.047 uM GV2 C28 H26 N6 O2 Cn1ccc2c1c....
8 5AJY ic50 = 0.496 uM 87T C20 H19 N5 O2 Cn1cc(cn1)....
9 3QPV - F6P C6 H13 O9 P C([C@@H]1[....
10 6HVI ic50 = 0.38 uM GV5 C22 H21 N5 O2 S CN(C)c1ccc....
11 5AK0 ic50 = 0.021 uM 8V1 C24 H25 N5 O2 Cn1cc(c2c1....
12 2I1V - F6P C6 H13 O9 P C([C@@H]1[....
13 4MA4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
14 5AJW ic50 = 0.104 uM S6L C24 H21 N5 O2 c1ccc(cc1)....
15 3QPW - PEP C3 H5 O6 P C=C(C(=O)O....
16 5AJZ ic50 = 0.343 uM MJP C17 H14 N4 O2 c1cc(ccc1N....
17 6HVJ ic50 = 0.028 uM GV8 C23 H18 N4 O3 S Cc1coc2c1c....
18 5HR5 Ki = 80 uM FLC C6 H5 O7 C(C(=O)[O-....
19 5HTK Kd = 80 uM FLC C6 H5 O7 C(C(=O)[O-....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: F6P; Similar ligands found: 20
No: Ligand ECFP6 Tc MDL keys Tc
1 F6P 1 1
2 TA6 1 1
3 FBP 0.666667 0.954545
4 AFP 0.666667 0.954545
5 SF9 0.564103 0.744186
6 PSV 0.564103 0.744186
7 LFR 0.564103 0.744186
8 SF6 0.564103 0.744186
9 FRU 0.564103 0.744186
10 FDP 0.55102 0.954545
11 F1X 0.531915 1
12 LBS 0.490566 0.755556
13 FRU FRU 0.490566 0.755556
14 0UB 0.464286 0.755556
15 S7P 0.444444 0.976744
16 AHG 0.431818 0.886364
17 SUP 0.40625 0.913043
18 RP5 0.404255 0.906977
19 HSX 0.404255 0.906977
20 ABF 0.404255 0.906977
Ligand no: 2; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Ligand no: 3; Ligand: FLC; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 FLC 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HR5; Ligand: ADP; Similar sites found with APoc: 721
This union binding pocket(no: 1) in the query (biounit: 5hr5.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 2QZ4 ADP 1.14504
2 1V8K ANP 1.21951
3 2IS6 ADP 1.31827
4 4R43 GDP 1.31827
5 5VHC BEF ADP 1.31827
6 5LB3 ADP 1.34831
7 6A20 ADP 1.373
8 1X8J A3P 1.4245
9 4IEE AGS 1.42857
10 2OBM ADP 1.44092
11 3DC4 ADP 1.45349
12 1W5T ANP 1.45631
13 1W5T ADP 1.45631
14 3ITJ CIT 1.47929
15 5NM7 GLY 1.50376
16 3RC3 ANP 1.50659
17 1M2Z BOG 1.55642
18 2DPY ADP 1.59817
19 5ZBR ANP 1.6
20 3VX3 ADP 1.6129
21 3COB ADP 1.62602
22 4KBF AMP 1.64384
23 2NCD ADP 1.66667
24 4A4Z ANP 1.69492
25 5MZN ADP 1.69492
26 1OXV ANP 1.69972
27 3ZFD ANP 1.7094
28 1J78 OLA 1.74672
29 4NCN GTP 1.75055
30 3U6B GDP 1.77665
31 5JBQ GDP 1.77665
32 4G5G GDP 1.77665
33 3U6K GDP 1.77665
34 1D8T GDP 1.78117
35 2BVN GNP 1.78117
36 5ZXD ATP 1.88324
37 5FG3 GDP 1.88324
38 1OS1 PYR 1.88324
39 4LYA ATP 1.88324
40 4ZDJ UTP 1.88324
41 1OS1 ATP 1.88324
42 2ZFI ADP 1.91257
43 4FCW ADP 1.92926
44 1G7C 5GP 1.96507
45 2ZTS ADP 1.99203
46 2OZE AGS 2.01342
47 3BFX A3P 2.02703
48 1W4R TTP 2.05128
49 1Z6T ADP 2.07156
50 4ZG4 VO4 ADP 2.07156
51 4FRZ ADP 2.07254
52 2HCJ GDP 2.08955
53 3BD9 A3P 2.14286
54 5W7Q GDP 2.14477
55 4H1V GNP 2.16802
56 3FYH ADP 2.17391
57 1ZCB GDP 2.20994
58 5CK5 GDP 2.21519
59 3T34 GDP 2.22222
60 3LRE ADP 2.25352
61 3TBK ANP 2.25989
62 4YJ1 ADP 2.25989
63 1IHU AF3 2.25989
64 1IHU ADP 2.25989
65 1MZC BNE 2.28833
66 1MZC FPP 2.28833
67 4TMZ GSP 2.31884
68 2BEK ATP 2.33463
69 2JJK R15 2.36686
70 3QVV 3QV 2.37288
71 3QVV A3P 2.37288
72 3P4X ADP 2.42131
73 2OBF SAH 2.42215
74 2OBF F83 2.42215
75 4X7R NTO 2.43408
76 1GWN GTP 2.43902
77 4PJ3 ANP 2.44821
78 4YS0 ADP 2.44821
79 2C42 PYR 2.44821
80 2C42 TPP 2.44821
81 4PFO ADP 2.44821
82 1ION ADP 2.46914
83 4LPS GDP 2.47934
84 3T1O GDP 2.52525
85 1SKQ GDP 2.52874
86 1FNN ADP 2.57069
87 3IO3 ADP 2.58621
88 1W78 ADP 2.60664
89 5XDR ADP 2.63653
90 2GDJ ANP 2.65152
91 4KVA GTP 2.6699
92 1M7B GTP 2.71739
93 5I34 GDP 2.72109
94 4J0Q GDP 2.77136
95 1R0X ATP 2.7972
96 1VKJ A3P 2.80702
97 3BER AMP 2.81124
98 5H4S RAM 2.8169
99 5WRI A3P 2.82486
100 5WRJ A3P 2.82486
101 1XKV ATP 2.83554
102 5GOE GDP 2.8436
103 5K5Z ANP 2.86624
104 5EE7 5MV 2.87611
105 1F9V ADP 2.88184
106 5IRR GSP 2.92208
107 1KK1 GNP 2.92683
108 4LJ9 ACP 2.94985
109 2CBZ ATP 2.95359
110 3Q85 GNP 2.95858
111 3EC1 GDP 2.98103
112 3WY9 GDP 2.99539
113 3WYA GDP 2.99539
114 6FAA ADP 3.01318
115 1QM5 PLP 3.01318
116 1E2K TMC 3.02115
117 2VBQ BSJ 3.0303
118 2O0J ADP 3.11688
119 2A5J GDP 3.14136
120 1A4R GNH 3.14136
121 1A4R GDP 3.14136
122 1TQ4 GDP 3.1477
123 2CE7 ADP 3.15126
124 4ITR GDP 3.16456
125 5UQW GDP 3.1746
126 1XPJ TLA 3.1746
127 1SVM ATP 3.18302
128 6AU6 GDP 3.18302
129 1DAR GDP 3.20151
130 5H68 AGS 3.23529
131 3QKT ANP 3.24484
132 2WMO GTP 3.27103
133 5YT0 GDP 3.2967
134 1WF3 GNP 3.32226
135 1NY5 ADP 3.35917
136 1XMV ADP 3.37079
137 1G3Q ADP 3.37553
138 5TSH ADP 3.38983
139 5TSH ANP 3.38983
140 3TK1 GDP 3.38983
141 2ZPA ADP 3.38983
142 1Q20 PLO 3.38983
143 1Q20 A3P 3.38983
144 1TAD ALF 3.39506
145 1TAD GDP 3.39506
146 4QOS ADP 3.39623
147 1JJV ATP 3.39806
148 4YC7 GNP 3.41207
149 5MEX SZZ 3.41615
150 5MEX PAP 3.41615
151 1JJ7 ADP 3.46154
152 3Q9L ATP 3.46154
153 4JZ8 CIT 3.47003
154 5BYK A3P 3.4749
155 5BYK OAQ 3.4749
156 2PZE ATP 3.49345
157 5N69 ADP 3.51759
158 2QG6 NMN 3.51759
159 5M7P ADP 3.52423
160 6FOG OXL 3.57143
161 4KVG GTP 3.57143
162 3X1Z GNP 3.59281
163 1P72 ADP 3.59281
164 5BN3 ADP 3.60577
165 1G6O ADP 3.63636
166 4RW3 SHV 3.64238
167 1T8U UAP SGN IDS SGN 3.67647
168 1T8U A3P 3.67647
169 3TMK T5A 3.7037
170 4PPF FLC 3.71429
171 4IDN GNP 3.71991
172 2ZR9 DTP 3.72493
173 3FKQ ATP 3.75335
174 1G7S GDP 3.76648
175 5X40 ACP 3.76712
176 5LTJ ADP 3.78151
177 3FWY ADP 3.82166
178 5W75 GDP 3.82653
179 4GOX A3P 3.83387
180 2ORV 4TA 3.84615
181 4D81 ADP 3.88693
182 3FVQ ATP 3.89972
183 3NHB ADP 3.92157
184 3KJI ADP 3.93701
185 1R6B ADP 3.9548
186 1SVK ALF GDP 3.96601
187 3WXM GTP 4.02685
188 1F6B GDP 4.0404
189 5KDO GDP 4.05405
190 3BFV ADP 4.05904
191 1Z83 AP5 4.08163
192 4K81 GTP 4.09357
193 1GOT GDP 4.10959
194 3G4Q MCH 4.10959
195 1F5N GNP 4.14313
196 4DBH OXL 4.14313
197 1ZIN AP5 4.14747
198 4WCX MET 4.16667
199 6D5E GNP 4.19162
200 4NE2 SH2 4.19162
201 4NE2 ADP 4.19162
202 6D55 GNP 4.19162
203 6D5M GNP 4.19162
204 6D5L GNP 4.19162
205 6D56 GNP 4.19162
206 6D5H GNP 4.19162
207 6D5J GNP 4.19162
208 6D59 GNP 4.19162
209 6BVM GNP 4.19162
210 6BVJ GNP 4.19162
211 6D5V GNP 4.19162
212 6D5G GNP 4.19162
213 6BVK GNP 4.19162
214 6BVL GNP 4.19162
215 6BVI GNP 4.19162
216 3DEF GDP 4.19847
217 5J1J ANP 4.21053
218 1WQ1 GDP 4.21687
219 1WQ1 AF3 4.21687
220 1NVV GNP 4.21687
221 1Y3A GDP 4.25532
222 2XTN GTP 4.2735
223 4Q1A UDP 4.28571
224 4Q1A 2XZ 4.28571
225 3DDC GNP 4.29448
226 1LVK MNT BEF 4.33145
227 2QQ0 ANP 4.34783
228 2QQ0 TMP 4.34783
229 2QQ0 ADP 4.34783
230 2QQ0 THM 4.34783
231 3DZD ADP 4.34783
232 2Q2Y ADP 4.35967
233 2Q2Y MKR 4.35967
234 5VGR GDP 4.40835
235 4OHY ANP 4.40835
236 6G14 G4P 4.42177
237 1BH2 GSP 4.44444
238 4LC1 GDP 4.45104
239 2W58 ADP 4.45545
240 1IN4 ADP 4.49102
241 1X1R GDP 4.49438
242 1FP6 ADP 4.49827
243 4BAS GNP 4.52261
244 3B5J 12D 4.52675
245 4HSE ADP 4.53401
246 1SQ5 ADP 4.54545
247 5E5U MLI 4.54545
248 1M5B BN1 4.56274
249 1PUJ GNP 4.60993
250 1QF9 ALF 4.63918
251 1QF9 ADP 4.63918
252 1QF9 C5P 4.63918
253 2GJ8 ALF GDP 4.65116
254 5WDR GNP 4.67836
255 2NGR GDP 4.70085
256 1EK0 GNP 4.70588
257 4WZA ACP 4.71014
258 4WZA ADP 4.71014
259 2ZE7 DST 4.74308
260 2ZE7 AMP 4.74308
261 3B7G ANP 4.78261
262 1MKY GDP 4.7836
263 2IXE ATP 4.79705
264 4WZ6 ATP 4.82759
265 5Z69 AGS 4.83871
266 5FHD ADP ALF 4.84988
267 5FTB ANP 4.84988
268 2QEN ADP 4.85714
269 5G3Y ADP 4.86726
270 3E70 GDP 4.87805
271 2B8W ALF 5GP 4.87805
272 2JAQ DCP 4.87805
273 6B4K ANP 4.88372
274 2FAH GDP 4.89642
275 1DAK ADP 4.91071
276 1DAK DPU 4.91071
277 1XP8 AGS 4.91803
278 3QXC ATP 4.95868
279 3CNL GNP 4.96183
280 1B0U ATP 4.96183
281 2ODE ALF GDP 4.96454
282 4DCT GDP 5.04386
283 5H7J GCP 5.08475
284 5GVR LMR 5.12821
285 5E95 GDP 5.15464
286 2CJW GDP 5.20833
287 1BG2 ADP 5.23077
288 1NST A3P 5.23077
289 5KSP GDP 5.26316
290 1RJ9 GCP 5.26316
291 3RT4 LP5 5.26316
292 1NHX PEP 5.27307
293 1NHX FTB 5.27307
294 2GMV UN8 5.27307
295 2GMV PEP 5.27307
296 3AB3 GDP 5.28455
297 1W7J ADP BEF 5.29801
298 3DKP ADP 5.30612
299 5LLB 6YZ 5.32319
300 1YRB GDP 5.34351
301 2A9K GDP 5.34759
302 5KSZ GCP 5.42453
303 2GCO GNP 5.47264
304 2GCN GDP 5.47264
305 2Y65 ADP 5.47945
306 5N26 CPT 5.49451
307 4DKX GDP 5.55556
308 1D5C GDP 5.55556
309 2G77 GDP 5.55556
310 1H65 GDP 5.55556
311 2G77 AF3 5.55556
312 2OG2 MLI 5.57103
313 4ZKD GDP 5.61122
314 2IYL GDP 5.6338
315 3MGB PAP 5.64263
316 4YDS ATP 5.64972
317 2WOJ ADP ALF 5.64972
318 3ZS9 ADP ALF 5.64972
319 2XTZ GSP 5.64972
320 5J1S ATP 5.69106
321 2Z5F A3P 5.7047
322 2VVG ADP 5.71429
323 1KO8 6PG 5.71429
324 2YOH WMJ 5.71429
325 1LFD GNP 5.74713
326 3A4M ADP 5.76923
327 2XT3 ADP 5.81395
328 5IRN ADP 5.83804
329 2X2T GAL NGA 5.88235
330 3EWA ANP 5.90062
331 4HDO GNP 5.90062
332 4HDQ GNP 5.90062
333 1AKY AP5 5.90909
334 3CX8 GSP 5.91133
335 1GOJ ADP 5.91549
336 3MD0 GDP 5.91549
337 3H4S ADP 5.92593
338 3RWO GDP 5.94595
339 1U8Z GDP 5.95238
340 2ZEJ GDP 5.97826
341 2QZS ADP 5.97938
342 2QZS GLC 5.97938
343 2QZS 250 5.97938
344 2WIC GNP 5.99251
345 1U0J ADP 5.99251
346 5WC2 ADP 6.01852
347 2FSH ANP 6.02637
348 5IFS ADP 6.02911
349 2F9L GDP 6.03015
350 1QF5 GDP 6.03248
351 1QF5 RPL 6.03248
352 3KTA AP5 6.04396
353 6AIC AMP 6.07477
354 3T5G GDP 6.07735
355 2F5X ASP 6.08974
356 1FQJ GDP 6.12245
357 1FQK GDP 6.12245
358 4KFU ACP 6.13208
359 3HU3 AGS 6.13497
360 3IUY AMP 6.14035
361 5EXT ADP 6.15385
362 4PX9 ADP 6.16438
363 6BSX E7S 6.17978
364 6BSX GDP 6.17978
365 4R2I ANP 6.19048
366 3BOS CDP 6.19835
367 1EM6 NBG 6.21469
368 1G6H ADP 6.22568
369 4R98 GNH 6.27306
370 1OIV GDP 6.28272
371 1OIX GDP 6.28272
372 4JLV ADP 6.3197
373 2XAU ADP 6.40301
374 4WEI GLC GAL 6.4982
375 3UIE ANP 6.5
376 4TTQ ATP 6.51163
377 1NN5 2DT 6.51163
378 1NN5 ANP 6.51163
379 1OE0 TTP 6.52174
380 4NON GDP 6.53846
381 5OEC GDP 6.55738
382 4JLS 3ZE 6.57895
383 1KAO GDP 6.58683
384 2WHX ADP 6.59134
385 3B9Q MLI 6.62252
386 2WKQ GTP 6.62651
387 1OYY AGS 6.69216
388 2RCN GDP 6.70391
389 1YZG GDP 6.70391
390 5W76 GDP 6.75325
391 2F3R G5P 6.76329
392 4LX0 BEF GDP 6.77966
393 5H7K GDP 6.80101
394 4A34 FUL 6.80272
395 2J5V PCA 6.81199
396 4IHQ ADP 6.82261
397 5L3W GDP 6.86275
398 2HT6 GDP 6.89655
399 1GRN GDP 6.89655
400 3R96 ACO 6.91489
401 3R96 AMP 6.91489
402 3FB4 AP5 6.94444
403 1HTW ADP 6.96203
404 2EW1 GNP 6.96517
405 2D7D ADP 6.96799
406 1T9D P22 6.96799
407 1T9D FAD 6.96799
408 1T9D 1MM 6.96799
409 1T9D PYD 6.96799
410 1T9D P25 6.96799
411 4TMK T5A 7.04225
412 1YZQ GNP 7.05882
413 1AQU A3P 7.07071
414 2CHG ANP 7.07965
415 1CR1 TTP 7.09459
416 2KIN ADP 7.14286
417 4P3Y GDP 7.14286
418 1Q19 SSC 7.15706
419 5JCP GDP ALF 7.1599
420 1NJF ADP 7.2
421 1NJF AGS 7.2
422 3Q72 GNP 7.22892
423 3VMF GTP 7.23861
424 1Z0F GDP 7.26257
425 2Y8E GNP 7.26257
426 5HCN GCP 7.27969
427 6BE0 COA 7.28477
428 5Y6N ADP 7.30594
429 1Z06 GNP 7.34463
430 5L3V GDP 7.35786
431 1CS4 GSP 7.36041
432 5L3S GNP 7.38255
433 1F2U ATP 7.38255
434 5L3S G 7.38255
435 2C77 GNP 7.40741
436 2C78 GNP 7.40741
437 1ZC3 GNP 7.42857
438 1UAD GNP 7.42857
439 1G41 ADP 7.43243
440 4RZ3 ADP 7.45763
441 5M04 GDP 7.5
442 4P4T GDP 7.5
443 5YV5 ADP 7.53296
444 1YQT ADP 7.53296
445 2GK6 ADP 7.53296
446 1M7G AV2 7.58294
447 1M7G ADP 7.58294
448 1M7G ADX 7.58294
449 1Y63 ADP 7.6087
450 4FHT DHB 7.64331
451 4V0K GDP 7.69231
452 2QTV GNP 7.72128
453 1M2O GNP 7.72128
454 1ZUI SKM 7.7381
455 4ZOH MCN 7.7381
456 2JLR ANP 7.76053
457 2ZPT A3P 7.79661
458 5JCZ GDP 7.80856
459 1CLU DBG 7.83133
460 1XX6 ADP 7.8534
461 4BFW ZVW 7.86164
462 1WDT GTP 7.9096
463 6CS8 F9Y 7.92079
464 6B8B ADP 8.03213
465 5G41 AP5 8.07175
466 1TU3 GNP 8.18713
467 1SVI GDP 8.20513
468 1R2Q GNP 8.23529
469 4XTR ADP 8.29493
470 4XTR ATP 8.29493
471 4XVU ATP 8.29493
472 1D2E GDP 8.31234
473 1JI0 ATP 8.33333
474 3MJH GTP 8.33333
475 5OCG GNP 8.46561
476 1S8F GDP 8.47458
477 1YTM ATP 8.47458
478 4V3I ASP LEU THR ARG PRO 8.56031
479 3KUD GDP 8.64198
480 1GUA GNP 8.64198
481 5TB5 GDP 8.64865
482 5TAR GDP 8.64865
483 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY 8.82353
484 1YVD GNP 8.87574
485 2EFE GNH 8.98876
486 5XKT GNP 9
487 2WJG GDP 9.04255
488 3EZ2 ADP 9.04523
489 4B47 GDP 9.09091
490 2BME GNP 9.13978
491 4RD0 GDP 9.15663
492 1VHT BA3 9.17431
493 1G3M PCQ 9.18367
494 1G3M A3P 9.18367
495 2C9O ADP 9.21053
496 1S3G AP5 9.21659
497 4M9Q GNP 9.22787
498 6FA4 GNP 9.24856
499 2FFQ GSP 9.35672
500 4CVN ADP 9.42408
501 4HI0 GDP 9.44882
502 5O2T GSP 9.46746
503 4ZNL BEF ADP 9.48905
504 1Z2A GDP 9.52381
505 6C90 ADP 9.61539
506 1B7T ADP 9.61539
507 6CRK GDP 9.85915
508 1GP2 GDP 9.85915
509 1Z0K GTP 9.88372
510 1MID LAP 9.89011
511 5L3R GCP 9.96678
512 2GKS ADP 9.98117
513 1X6V ADP 9.98117
514 2WCU FUC 10.0671
515 3A1S GDP 10.0775
516 1ZD9 GDP 10.1064
517 1BO4 COA 10.119
518 4D0G GTP 10.1449
519 1ZJ6 G3D 10.1604
520 2AWN ADP 10.2362
521 2WJH GDP 10.241
522 2WJH FLC 10.241
523 1YZN GNP 10.2703
524 4C4P GNP 10.2804
525 1RYH GNP 10.3448
526 2FNA ADP 10.3641
527 2D2F ADP 10.4
528 2GWH A3P 10.4027
529 1S7N COA 10.4396
530 1UPT GTP 10.5263
531 5BQ5 ADP BEF 10.582
532 1G16 GDP 10.5882
533 5U32 GDP 10.5932
534 4U00 ADP 10.6557
535 4WOP CTP 10.6667
536 3SBD GNP 10.6952
537 2X7I CIT 10.7143
538 2B8T THM 10.7623
539 3PQC GDP 10.7692
540 1KK8 BEF ADP 10.7914
541 5DI3 GNP 10.8108
542 1R4A GNP 10.9091
543 3TNF GNP 10.9195
544 3QBT GNP 10.9195
545 4LHW GNP 10.9195
546 1I4D GDP 10.9375
547 3H86 AP5 10.9375
548 4PC3 GDP 10.9929
549 5UIV ADP 11.0132
550 3T12 GDP ALF 11.0294
551 1XEX ATP 11.0465
552 5TIV A3P 11.0672
553 2C5L GTP 11.1111
554 4E03 ADP 11.165
555 2BCG GDP 11.2583
556 1MH1 GNP 11.2903
557 3CPJ GDP 11.3082
558 3REF GDP 11.3402
559 2FH5 GTP 11.3514
560 1G4U GDP 11.413
561 1DS6 GDP 11.4583
562 1E96 GTP 11.4583
563 4AG5 ADP 11.4796
564 2UZI GTP 11.5385
565 4ZI2 GNP 11.5789
566 1LVG ADP 11.6162
567 4GOJ GNP 11.6402
568 5WLB GNP 11.7647
569 6DEF GCP 11.7647
570 2FJU GSP 11.7978
571 5I0H ADP BEF 11.8644
572 2W2X GSP 11.8919
573 1L2T ATP 11.9149
574 1OW3 GDP 11.9171
575 1HE1 GDP 11.9318
576 4MKF AP5 11.9816
577 1FZQ GDP 12.1547
578 3RLF ANP 12.1622
579 3IIJ ADP 12.2222
580 3KIF GDL 12.2642
581 5SZH GNP 12.3153
582 5IRC GDP 12.3656
583 2HF9 GSP 12.3894
584 4D0N GDP 12.4324
585 5HPY GDP 12.4324
586 6BCB GSP 12.4324
587 6BCA GSP 12.4324
588 4MKG AP5 12.4424
589 2HV8 GTP 12.5
590 1CXZ GSP 12.6374
591 1Z0A GDP 12.6437
592 4TL6 ANP 12.6482
593 3TKL GTP 12.7551
594 2CDC XYS 12.8415
595 4XSH GSP 12.8492
596 5EE5 GTP 12.8655
597 1TX4 ALF GDP 12.9944
598 4GBM A3P 13.0031
599 3DOE GTP 13.0208
600 1KMQ GNP 13.0435
601 1T5C ADP 13.1805
602 5H67 ATP 13.2979
603 1NRJ GTP 13.3028
604 4XOI GTP 13.3333
605 1KSH GDP 13.4409
606 2OFW ADX 13.4615
607 5MVR ADP 13.5802
608 3SFV GDP 13.8122
609 5O74 GDP 13.8889
610 5ZB0 ADP 14.1414
611 5ZB0 TYD 14.1414
612 1UKZ ADP 14.2857
613 3NKV GNP 14.2857
614 1VG0 GDP 14.4928
615 1VG8 GNP 14.4928
616 4QC6 30N 14.5251
617 3W5J GDP 14.7059
618 3ZQ6 ADP ALF 14.8148
619 2PL3 ADP 14.8305
620 3ZIA ATP 15.1079
621 3ZIA ADP 15.1079
622 5LEF GTP 15.1515
623 1KY3 GDP 15.3846
624 2F7A BEZ 15.5172
625 1NF3 GNP 15.625
626 2PEZ DAT 15.6425
627 2PEZ GGZ 15.6425
628 3KPE TM3 15.6863
629 4U5X GNP 15.7303
630 1D2N ANP 15.8088
631 2CJU PHX 15.9292
632 3QF7 ANP 16
633 4DID GDP 16.0622
634 1OFH ADP 16.092
635 1VG1 GDP 16.2162
636 1VG9 GDP 16.2162
637 4YMU ATP 16.25
638 5KUT GDP 16.4021
639 2J0V GDP 16.5094
640 4NU0 AP5 16.5899
641 1RRC ADP 16.6113
642 3LXR GDP 16.6667
643 2OM2 GDP 16.6667
644 2VB6 ADP BEF 16.7785
645 4X8O AP5 16.8224
646 4UXH T5A 16.8478
647 5Z2M GTP 17.6136
648 1W0J ADP 17.6471
649 2CK3 ANP 17.6471
650 2V7Q ATP 17.6471
651 2V7Q ADP 17.6471
652 1W0J ADP BEF 17.6471
653 2CK3 ADP 17.6471
654 5UWS GNP 17.7215
655 5UWP GNP 17.7215
656 5DI9 GNP 17.7215
657 6CIT GNP 17.7215
658 5UWO GNP 17.7215
659 5DHF GNP 17.7215
660 5UWT GNP 17.7215
661 5UWU GNP 17.7215
662 5UWQ GNP 17.7215
663 5DIF GNP 17.7215
664 5UWW GNP 17.7215
665 5UWJ GNP 17.7215
666 5UWI GNP 17.7215
667 5UWR GNP 17.7215
668 1UJ2 C5P 17.8571
669 1UJ2 ADP 17.8571
670 4V03 ADP 17.8988
671 1Z08 GNP 18.2353
672 4YLG GDP 18.4971
673 3GJ0 GDP 19.0045
674 3GJ7 GDP 19.0045
675 3GJ4 GDP 19.0045
676 3GJ5 GDP 19.0045
677 2D7C GTP 19.0476
678 5XC5 GTP 19.3182
679 3CH5 GDP 19.4444
680 5BXQ GDP 19.4444
681 4HAT GNP 19.4444
682 1IBR GNP 19.4444
683 3GJX GTP 19.4444
684 1T0S BML 19.7674
685 4XGU ADP 19.8113
686 5UPK GNP 20.2312
687 3BC1 GNP 20.339
688 3FIU POP 20.4819
689 4BQS ADP 21.0227
690 4BQS K2Q 21.0227
691 4OGQ 7PH 21.6216
692 3GJ8 GDP 21.7391
693 6BC0 GSP 22
694 3AQ4 GDP 23.3696
695 3GJ3 GDP 24.2424
696 3WYF GTP 27.3973
697 3M1I GTP 27.3973
698 3E5H GNP 28.6517
699 2X77 GDP 29.6296
700 1O3Y GTP 30.7229
701 2J59 GTP 30.7229
702 1J2J GTP 30.7229
703 1RE0 GDP 31.0976
704 1S9D GDP 31.0976
705 3RAB GNP 31.3609
706 4QM7 GTP 31.5789
707 5UWH GNP 31.8182
708 1MR3 G3D 32.0442
709 2CDN ADP 32.3383
710 1GXU 2HP 32.967
711 3WYG GTP 32.967
712 2QN6 GDP 33.3333
713 1WA5 GTP 34.0909
714 2A5F GTP 34.8571
715 4KAX GTP 35.503
716 3PCR GTP 35.8025
717 2W83 GTP 36.3636
718 2RGX AP5 36.4078
719 4OI4 ATP 36.5217
720 3N5C GDP 37.037
721 1Z0J GTP 38.9831
Pocket No.: 2; Query (leader) PDB : 5HR5; Ligand: F6P; Similar sites found with APoc: 14
This union binding pocket(no: 2) in the query (biounit: 5hr5.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 4XWM CBI 3.01318
2 3N2O AG2 3.57815
3 1JGS SAL 5.07246
4 2CI5 HCS 6.69014
5 1X0P FAD 7.69231
6 3LL4 2FP 7.87671
7 3OI7 OI7 8.21918
8 2HHJ DG2 29.2135
9 2HHJ 3PG 29.2135
10 3GP3 SEP 30.7393
11 3FDZ DG2 31.1284
12 3FDZ 3PG 31.1284
13 1BQ4 BHC 32.9268
14 4IJ6 SEP 44.5498
Pocket No.: 3; Query (leader) PDB : 5HR5; Ligand: FLC; Similar sites found with APoc: 38
This union binding pocket(no: 3) in the query (biounit: 5hr5.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1EZ0 NAP 1.56863
2 5UY8 AMZ 1.69492
3 5UY8 8UM 1.69492
4 4B98 PXG 2.00893
5 3COW 52H 2.32558
6 2NYA MGD 2.44821
7 5I7A 68Q 2.45399
8 2IHK CSF 2.50627
9 154L NAG NAG NAG 2.7027
10 3WR7 COA 2.94118
11 4A1O AMZ 3.25048
12 1R27 MGD 3.38983
13 2PTR 2SA 3.4632
14 4ZAC 4LU 3.77734