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Receptor
PDB id Resolution Class Description Source Keywords
5HPY 2.4 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH HUMAN MYO RHOGAP DOMAIN HOMO SAPIENS COMPLEX RHO GTPASES RHOGAP GENE REGULATION-SIGNALING PROTCOMPLEX
Ref.: NONCANONICAL MYO9B-RHOGAP ACCELERATES RHOA GTP HYDR A DUAL-ARGININE-FINGER MECHANISM J.MOL.BIOL. V. 428 3043 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MGF F:201;
B:201;
Invalid;
Invalid;
none;
none;
submit data
81.3 F3 Mg F[Mg-...
MG B:202;
F:204;
F:203;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GDP B:203;
F:202;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HPY 2.4 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH HUMAN MYO RHOGAP DOMAIN HOMO SAPIENS COMPLEX RHO GTPASES RHOGAP GENE REGULATION-SIGNALING PROTCOMPLEX
Ref.: NONCANONICAL MYO9B-RHOGAP ACCELERATES RHOA GTP HYDR A DUAL-ARGININE-FINGER MECHANISM J.MOL.BIOL. V. 428 3043 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5M70 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5M6X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1OW3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4XSG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 3LXR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 3LWN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 3LW8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4XOI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
9 6BCA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
10 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 6BC0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
13 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 1CXZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
15 4D0N - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 1HE1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5M70 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 5M6X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1OW3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 2WMO - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 2WMN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 2NGR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4XSG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
9 3LXR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 3LWN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 3LW8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 4XOI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
13 6BCA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
14 1E96 Kd = 2.7 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
15 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 6BC0 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
18 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
19 1CXZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
20 4YC7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
21 4D0N - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HPY; Ligand: GDP; Similar sites found with APoc: 583
This union binding pocket(no: 1) in the query (biounit: 5hpy.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 3LN9 FLC None
2 3MD0 GDP 2.16216
3 3IIJ ADP 2.22222
4 3UIE ANP 2.7027
5 2QZ4 ADP 2.7027
6 2GDJ ANP 3.01724
7 3ZS9 ADP ALF 3.01724
8 2WOJ ADP ALF 3.01724
9 1QF9 ALF 3.09278
10 1QF9 ADP 3.09278
11 1QF9 C5P 3.09278
12 1VHT BA3 3.21101
13 3EWA ANP 3.24324
14 4V03 ADP 3.24324
15 2CHG ANP 3.24324
16 4ZNL BEF ADP 3.24324
17 3BFV ADP 3.24324
18 3L6C MLI 3.24324
19 1W5T ANP 3.24324
20 1W5T ADP 3.24324
21 5WRI A3P 3.24324
22 5WRJ A3P 3.24324
23 3TK1 GDP 3.44828
24 3E70 GDP 3.44828
25 1G6O ADP 3.44828
26 2NVK FAD 3.44828
27 1M2Z BOG 3.44828
28 3IUY AMP 3.50877
29 1YQT ADP 3.78378
30 3FWY ADP 3.78378
31 2ZFI ADP 3.78378
32 4RZ3 ADP 3.78378
33 5YV5 ADP 3.78378
34 1W4R TTP 3.78378
35 2ORV 4TA 3.78378
36 2O0J ADP 3.78378
37 1U1I NAD 3.78378
38 4FRZ ADP 4.31034
39 5MZN ADP 4.31034
40 1D2N ANP 4.31034
41 2FH5 GTP 4.32432
42 1JI0 ATP 4.32432
43 1H65 GDP 4.32432
44 5L3V GDP 4.32432
45 3ZQ6 ADP ALF 4.32432
46 3VX3 ADP 4.32432
47 5LTJ ADP 4.32432
48 5H68 AGS 4.32432
49 3P4X ADP 4.32432
50 2GK6 ADP 4.32432
51 5UIV ADP 4.32432
52 3FYH ADP 4.32432
53 5LTJ BEF 4.32432
54 2ZTS ADP 4.32432
55 5J5R 6G1 4.32432
56 5J5R IMP 4.32432
57 6FMC DUE 4.43038
58 3KTA AP5 4.62428
59 1NN5 ANP 4.65116
60 1NN5 2DT 4.65116
61 4QM7 GTP 4.67836
62 5W7Q GDP 4.74138
63 4GOX A3P 4.74138
64 1G3M PCQ 4.74138
65 1G3M A3P 4.74138
66 2IXE ATP 4.79705
67 6B8B ADP 4.81928
68 2WJG GDP 4.86486
69 2C78 GNP 4.86486
70 2C77 GNP 4.86486
71 2OG2 MLI 4.86486
72 4ZKD GDP 4.86486
73 3B9Q MLI 4.86486
74 5AK0 8V1 4.86486
75 4D81 ADP 4.86486
76 3DZD ADP 4.86486
77 3KJI ADP 4.86486
78 3BOS CDP 4.86486
79 3TMK T5A 4.86486
80 1IN4 ADP 4.86486
81 6FAA ADP 4.86486
82 2J5V PCA 4.86486
83 4UXH T5A 4.8913
84 2W58 ADP 4.9505
85 5EXT ADP 5
86 1LVG ADP 5.05051
87 4MKF AP5 5.06912
88 4BQS K2Q 5.11364
89 4BQS ADP 5.11364
90 1D2E GDP 5.17241
91 2XTN GTP 5.17241
92 1Q19 SSC 5.17241
93 1SKQ GDP 5.40541
94 5KUT GDP 5.40541
95 4LC1 GDP 5.40541
96 6G14 G4P 5.40541
97 1PUJ GNP 5.40541
98 4M9Q GNP 5.40541
99 3ZFD ANP 5.40541
100 2DPY ADP 5.40541
101 4NON GDP 5.40541
102 5LB3 ADP 5.40541
103 4HSE ADP 5.40541
104 1XKV ATP 5.40541
105 2CBZ ATP 5.40541
106 1IHU AF3 5.40541
107 5VGR GDP 5.40541
108 4YMU ATP 5.40541
109 1IHU ADP 5.40541
110 1GPJ CIT 5.40541
111 5NM7 GLY 5.40541
112 5ZB0 TYD 5.55556
113 5ZB0 ADP 5.55556
114 3FB4 AP5 5.55556
115 1XPJ TLA 5.55556
116 2WIC GNP 5.60345
117 5XDR ADP 5.60345
118 5K5Z ANP 5.60345
119 4IEE AGS 5.60345
120 1QXA GLY GLY GLY 5.60345
121 1OE0 TTP 5.65217
122 4E03 ADP 5.82524
123 4R98 GNH 5.94595
124 4P4T GDP 5.94595
125 3CNL GNP 5.94595
126 2CDN ADP 5.94595
127 1XMV ADP 5.94595
128 5X40 ACP 5.94595
129 1SVM ATP 5.94595
130 4NTO 1PW 5.94595
131 1FEC FAD 5.94595
132 4GBM A3P 5.94595
133 2GQT FAD 5.97015
134 4MKG AP5 5.99078
135 2WJH GDP 6.0241
136 2WJH FLC 6.0241
137 1GOJ ADP 6.03448
138 3Q9L ATP 6.03448
139 2FSH ANP 6.03448
140 5LLB 6YZ 6.03448
141 4OI4 ATP 6.08696
142 5U32 GDP 6.46552
143 5WC2 ADP 6.46552
144 2GKS ADP 6.46552
145 2FNA ADP 6.46552
146 3COB ADP 6.48649
147 5XKT GNP 6.48649
148 5IRR GSP 6.48649
149 4DDY DN6 6.48649
150 6B4K ANP 6.48649
151 3DKP ADP 6.48649
152 4KVL PLM 6.48649
153 5M7P ADP 6.48649
154 4BFW ZVW 6.48649
155 4QOS ADP 6.48649
156 1RRC ADP 6.48649
157 4ZDJ UTP 6.48649
158 5MEX SZZ 6.48649
159 5MEX PAP 6.48649
160 3X27 TRP 6.48649
161 3VMF GTP 6.89655
162 3LRE ADP 6.89655
163 1QF5 GDP 6.89655
164 1QF5 RPL 6.89655
165 1E2K TMC 6.89655
166 3AI8 HNQ 6.89655
167 2BEK ATP 7.02703
168 5VHC BEF ADP 7.02703
169 4JLV ADP 7.02703
170 2JLR ANP 7.02703
171 1OS1 PYR 7.02703
172 1OS1 ATP 7.02703
173 3QVV 3QV 7.02703
174 3QVV A3P 7.02703
175 3CV2 OXL 7.02703
176 2QQ0 ANP 7.06522
177 2QQ0 TMP 7.06522
178 2QQ0 ADP 7.06522
179 2QQ0 THM 7.06522
180 3FVQ ATP 7.24234
181 2PEZ GGZ 7.26257
182 2PEZ DAT 7.26257
183 4NE2 SH2 7.32759
184 4NE2 ADP 7.32759
185 2IYL GDP 7.39437
186 5MVR ADP 7.40741
187 1XEX ATP 7.55814
188 3T34 GDP 7.56757
189 4Q1A UDP 7.56757
190 4Q1A 2XZ 7.56757
191 1ZIN AP5 7.56757
192 2ZJ5 ADP 7.56757
193 3BER AMP 7.56757
194 2WHX ADP 7.75862
195 4IHQ ADP 7.75862
196 4R43 GDP 7.75862
197 4XGU ADP 7.75862
198 1G41 ADP 7.75862
199 1G3Q ADP 7.75862
200 1NHX FTB 7.75862
201 1NHX PEP 7.75862
202 2GMV UN8 7.75862
203 2GMV PEP 7.75862
204 4XTR ATP 7.8341
205 4XVU ATP 7.8341
206 4XTR ADP 7.8341
207 4KFU ACP 8.01887
208 1DAK ADP 8.03571
209 1DAK DPU 8.03571
210 4R2I ANP 8.09524
211 4DCT GDP 8.10811
212 5CK5 GDP 8.10811
213 4H1V GNP 8.10811
214 4LYA ATP 8.10811
215 1IWE IMP 8.10811
216 4WZA ADP 8.10811
217 1FP6 ADP 8.10811
218 4WZA ACP 8.10811
219 3IO3 ADP 8.10811
220 2QG6 NMN 8.10811
221 2ZPA ADP 8.10811
222 1DAR GDP 8.18966
223 5M04 GDP 8.18966
224 4KVA GTP 8.18966
225 5L3W GDP 8.18966
226 4PX9 ADP 8.18966
227 5L3S GNP 8.18966
228 5TIV A3P 8.18966
229 3BFX A3P 8.18966
230 5L3S G 8.18966
231 3PQC GDP 8.20513
232 5BQ5 ADP BEF 8.46561
233 2FAH GDP 8.62069
234 2OZE AGS 8.62069
235 4PJ3 ANP 8.62069
236 2D2F ADP 8.64865
237 5Y6N ADP 8.64865
238 1UKZ ADP 8.64865
239 1U0J ADP 8.64865
240 2BO4 FLC 8.64865
241 2RGX AP5 8.73786
242 4NU0 AP5 8.75576
243 2YOH WMJ 9.04762
244 5W76 GDP 9.05172
245 3WXM GTP 9.05172
246 1SQ5 ADP 9.05172
247 4YJ1 ADP 9.05172
248 3QXC ATP 9.05172
249 5H7K GDP 9.18919
250 5H7J GCP 9.18919
251 4AG5 ADP 9.18919
252 1M7G AV2 9.18919
253 2HF9 GSP 9.18919
254 1M7G ADX 9.18919
255 1M7G ADP 9.18919
256 1S3G AP5 9.18919
257 2GWH A3P 9.18919
258 2PL3 ADP 9.18919
259 4GID 0GH 9.18919
260 1OFH ADP 9.1954
261 1YRB GDP 9.48276
262 5W75 GDP 9.48276
263 5BN3 ADP 9.48276
264 2XAU ADP 9.48276
265 6A20 ADP 9.72973
266 1Z6T ADP 9.72973
267 5I34 GDP 9.72973
268 3A1S GDP 9.91379
269 3EZ2 ADP 9.91379
270 1VKJ A3P 9.91379
271 1K6M AGS 9.91379
272 1SVI GDP 10.2703
273 4U00 ADP 10.2703
274 3B5J 12D 10.2703
275 1XX6 ADP 10.2703
276 3B7G ANP 10.2703
277 1P72 ADP 10.2703
278 5GVR LMR 10.2703
279 3TBK ANP 10.2703
280 1NY5 ADP 10.2703
281 5J1J ANP 10.2703
282 2C9O ADP 10.2703
283 1X8J A3P 10.2703
284 3U6B GDP 10.3448
285 3U6K GDP 10.3448
286 2BVN GNP 10.3448
287 2HCJ GDP 10.3448
288 5JBQ GDP 10.3448
289 4G5G GDP 10.3448
290 1D8T GDP 10.3448
291 4PC3 GDP 10.3448
292 1WDT GTP 10.3448
293 4TTQ ATP 10.6977
294 1BO4 COA 10.7143
295 1OXV ANP 10.7759
296 5BYK A3P 10.7759
297 5BYK OAQ 10.7759
298 2Z5F A3P 10.7759
299 4IOK ADP 10.7759
300 4IOK XPO 10.7759
301 4X8O AP5 10.8108
302 3DC4 ADP 10.8108
303 1Z83 AP5 10.8108
304 1YTM ATP 11.2069
305 1G6H ADP 11.2069
306 2QN6 GDP 11.3514
307 3WY9 GDP 11.3514
308 4RD0 GDP 11.3514
309 3WYA GDP 11.3514
310 2PZE ATP 11.3514
311 1R0X ATP 11.3514
312 4WEI GLC GAL 11.3514
313 2X7I CIT 11.3514
314 1OYY AGS 11.3514
315 4YDS ATP 11.4035
316 3RC3 ANP 11.6379
317 4AUT FAD 11.6379
318 3H4S ADP 11.8519
319 1TQ4 GDP 11.8919
320 5IFS ADP 11.8919
321 3HU3 AGS 11.8919
322 1L2T ATP 11.8919
323 1F5N GNP 11.8919
324 2XCU C5P 11.8919
325 3QKT ANP 11.8919
326 5G3Y ADP 11.9469
327 5ZXD ATP 12.069
328 1ION ADP 12.069
329 1F2U ATP 12.0805
330 1JJ7 ADP 12.4324
331 1G7C 5GP 12.4324
332 1B0U ATP 12.4324
333 5HR5 ADP 12.4324
334 2B8W ALF 5GP 12.4324
335 3W6G FLC 12.4324
336 5J1S ATP 12.4324
337 4WOP CTP 12.4444
338 5TSH ANP 12.5
339 5TSH ADP 12.5
340 5FHD ADP ALF 12.5
341 5FTB ANP 12.5
342 1X6V ADP 12.5
343 1LVK MNT BEF 12.931
344 1P9B GDP 12.973
345 1JJV ATP 13.1068
346 4CVN ADP 13.1387
347 4A4Z ANP 13.3621
348 2OBM ADP 13.5135
349 3FKQ ATP 13.5135
350 5L3R GCP 13.5135
351 2IS6 ADP 13.5135
352 1KO8 6PG 13.7143
353 4OHY ANP 13.7931
354 2AWN ADP 14.0541
355 4TL6 ANP 14.0541
356 4WZ6 ATP 14.0541
357 1AQU A3P 14.0541
358 1FNN ADP 14.2241
359 5YT0 GDP 14.5946
360 5FG3 GDP 14.5946
361 5GOE GDP 14.5946
362 2XTZ GSP 14.5946
363 3NHB ADP 14.6552
364 3RLF ANP 14.6552
365 2ZPT A3P 14.6552
366 4P3Y GDP 14.8352
367 1ZUI SKM 14.881
368 1NJF ADP 15.0862
369 1NJF AGS 15.0862
370 3DEF GDP 15.1351
371 3ITJ CIT 15.1351
372 1G7S GDP 15.5172
373 2QEN ADP 15.5172
374 4PPF FLC 15.6757
375 5Z69 AGS 15.6757
376 1UJ2 ADP 15.9483
377 1UJ2 C5P 15.9483
378 3QF7 ANP 16
379 5G41 AP5 16.1435
380 1WF3 GNP 16.2162
381 4FCW ADP 16.2162
382 1CR1 TTP 16.2162
383 1XP8 AGS 16.2162
384 3MGB PAP 16.2162
385 1KK1 GNP 16.7568
386 3CX8 GSP 16.7568
387 1BH2 GSP 16.7568
388 3EC1 GDP 16.7568
389 3AB3 GDP 16.7568
390 1Y3A GDP 16.7568
391 6CRK GDP 16.7568
392 1GP2 GDP 16.7568
393 4BAS GNP 16.7568
394 1ZCB GDP 16.7568
395 2ODE ALF GDP 16.7568
396 1SVK ALF GDP 16.7568
397 5E5U MLI 17.0854
398 2CK3 ANP 17.2414
399 1W0J ADP 17.2414
400 1W0J ADP BEF 17.2414
401 2CK3 ADP 17.2414
402 1AKY AP5 17.2727
403 1MKY GDP 17.2973
404 2OFW ADX 17.2973
405 1NRJ GTP 17.4312
406 3ZIA ADP 17.4603
407 3ZIA ATP 17.4603
408 1GXU 2HP 17.5824
409 4J0Q GDP 17.8378
410 1HTW ADP 18.3544
411 1TAD ALF 18.3784
412 1TAD GDP 18.3784
413 4U60 SIA GAL NGA 18.3784
414 4U60 SIA 18.3784
415 5H67 ATP 18.75
416 4LPS GDP 18.9189
417 3W5J GDP 18.9189
418 2ZR9 DTP 18.9189
419 1GOT GDP 19.1781
420 4LJ9 ACP 19.4595
421 2X77 GDP 20.1058
422 1CS4 GSP 20.5405
423 4B5W PYR 20.5405
424 2V5K OXM 20.5405
425 4IDN GNP 20.5405
426 1QHH ATP 20.8696
427 6AU6 GDP 21.0811
428 3A4M ADP 21.0811
429 4HI0 GDP 21.0811
430 2V7Q ATP 21.2121
431 2V7Q ADP 21.2121
432 1YZG GDP 21.7877
433 1ZJ6 G3D 22.1622
434 1R6B ADP 22.1622
435 4YS0 ADP 22.1622
436 2BIF SIN 22.4138
437 2BIF ANP 22.4138
438 6CS8 F9Y 22.7027
439 2CE7 ADP 22.8448
440 2A5F GTP 22.8571
441 5KDO GDP 22.973
442 2VOH CIT 23.0769
443 1RJ9 GCP 23.2432
444 5IRN ADP 23.2432
445 5EE5 GTP 23.9766
446 3PCR GTP 24.0741
447 1MR3 G3D 24.3094
448 4KBF AMP 24.3243
449 6DEF GCP 24.569
450 3N5C GDP 24.6914
451 4NCN GTP 24.8649
452 4TMZ GSP 24.8649
453 6C90 ADP 25
454 1Y63 ADP 25.5435
455 2D7D ADP 27.5
456 5KSP GDP 27.5676
457 5KSZ GCP 27.5676
458 1KSH GDP 28.1081
459 2RCN GDP 28.1081
460 3DOE GTP 28.1081
461 1F6B GDP 28.1081
462 2GJ8 ALF GDP 28.4884
463 3H86 AP5 29.1667
464 5HCN GCP 29.7297
465 4KAX GTP 30.1775
466 1R4A GNP 31.3725
467 2W83 GTP 32.1212
468 3AQ4 GDP 32.6087
469 1FQJ GDP 32.973
470 1FQK GDP 32.973
471 1FQJ ALF 32.973
472 1FQK ALF 32.973
473 1UPT GTP 33.3333
474 3T12 GDP ALF 33.5135
475 3T1O GDP 33.5135
476 5XC5 GTP 33.5227
477 4V0K GDP 33.7278
478 4YLG GDP 34.104
479 3M1I GTP 34.5946
480 3WYF GTP 34.5946
481 2ZEJ GDP 34.7826
482 3GJ4 GDP 35.1351
483 3GJ7 GDP 35.1351
484 3GJ5 GDP 35.1351
485 1ZD9 GDP 35.1351
486 3GJ8 GDP 35.1351
487 3GJX GTP 35.1351
488 3WYG GTP 35.1648
489 5DIF GNP 35.6757
490 5UWO GNP 35.6757
491 5UWU GNP 35.6757
492 5UWQ GNP 35.6757
493 5UWW GNP 35.6757
494 5UWP GNP 35.6757
495 4HAT GNP 35.6757
496 6CIT GNP 35.6757
497 5UWS GNP 35.6757
498 5UWT GNP 35.6757
499 5UWH GNP 35.6757
500 5DHF GNP 35.6757
501 3GJ3 GDP 35.6757
502 5BXQ GDP 35.6757
503 3CH5 GDP 35.6757
504 3GJ0 GDP 35.6757
505 5UWJ GNP 35.6757
506 5UWI GNP 35.6757
507 5UWR GNP 35.6757
508 1IBR GNP 35.6757
509 5DI9 GNP 35.6757
510 1J2J GTP 36.1446
511 1O3Y GTP 36.1446
512 2J59 GTP 36.1446
513 1RE0 GDP 37.1951
514 1S9D GDP 37.1951
515 1M2O GNP 37.2973
516 1WA5 GTP 37.5
517 4B47 GDP 37.8378
518 5OEC GDP 38.2514
519 2OM2 GDP 38.8889
520 2G77 GDP 38.9189
521 1Z06 GNP 39.4595
522 4ZI2 GNP 40.5263
523 4GOJ GNP 40.7407
524 2QTV GNP 41.3174
525 3BC1 GNP 41.6216
526 2CJW GDP 41.6216
527 5DI3 GNP 41.6216
528 3Q72 GNP 42.1687
529 3RWO GDP 43.2432
530 2BME GNP 43.2432
531 1FZQ GDP 43.6464
532 3CPJ GDP 43.7838
533 3E5H GNP 43.8202
534 1OIX GDP 44.3243
535 1OIV GDP 44.8649
536 5LEF GTP 44.8649
537 1X1R GDP 44.9438
538 2A5J GDP 45.4054
539 2BCG GDP 45.4054
540 2F9L GDP 45.4054
541 3Q85 GNP 45.5621
542 1Z0F GDP 45.8101
543 1Z0K GTP 45.9302
544 1VG1 GDP 45.9459
545 1VG9 GDP 45.9459
546 1VG0 GDP 45.9459
547 3TKL GTP 45.9459
548 1YZN GNP 45.9459
549 1VG8 GNP 45.9459
550 4D0G GTP 46.2857
551 5JCZ GDP 46.3687
552 3T5G GDP 46.4088
553 2HT6 GDP 46.5517
554 5O74 GDP 46.6667
555 4LX0 BEF GDP 46.8927
556 5SZH GNP 47.027
557 1EK0 GNP 47.0588
558 5UQW GDP 47.0899
559 6BSX GDP 47.191
560 6BSX E7S 47.191
561 1S8F GDP 47.4576
562 5OCG GNP 47.5676
563 2A9K GDP 47.5936
564 1Z0J GTP 47.6471
565 2HV8 GTP 47.6744
566 5Z2M GTP 47.7273
567 1TU3 GNP 47.9532
568 4C4P GNP 47.9769
569 3NKV GNP 48
570 2Y8E GNP 48.0447
571 3SFV GDP 48.0663
572 4DKX GDP 48.1081
573 1D5C GDP 48.1481
574 3MJH GTP 48.2143
575 1R2Q GNP 48.2353
576 1KY3 GDP 48.3517
577 2D7C GTP 48.503
578 1ZC3 GNP 48.5714
579 1UAD GNP 49.1429
580 2EFE GNH 49.1713
581 1KAO GDP 49.7006
582 1YVD GNP 49.7041
583 5WDR GNP 49.7076
Pocket No.: 2; Query (leader) PDB : 5HPY; Ligand: GDP; Similar sites found with APoc: 17
This union binding pocket(no: 2) in the query (biounit: 5hpy.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 4HUT ATP None
2 3A70 NPO 4.31034
3 6FP4 E1T 5.40541
4 3B8I OXL 5.94595
5 2XMY CDK 6.03448
6 1BZL FAD 7.02703
7 1SR7 MOF 7.32759
8 1ME8 RVP 7.56757
9 5DZ2 212 8.18966
10 4X1Z FUC GAL NDG 9.18919
11 1QMG DMV 10.2703
12 5AHO TLA 10.3448
13 1Q20 A3P 12.4324
14 1Q20 PLO 12.4324
15 1ZEI CRS 13.2075
16 5X20 AOT 14.0541
17 2G77 AF3 38.9189
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