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Receptor
PDB id Resolution Class Description Source Keywords
5HGZ 1.38 Å EC: 2.3.1.48 CRYSTAL STRUCTURE OF HUMAN NAA60 IN COMPLEX WITH ACETYL-COA HOMO SAPIENS N-TERMINAL ACETYLATION COMPLEX NATS PROTEIN MODIFICAITONTRANSFERASE
Ref.: STRUCTURE AND FUNCTION OF HUMAN NAA60 (NATF), A GOLGI-LOCALIZED BI-FUNCTIONAL ACETYLTRANSFERASE SCI REP V. 6 31425 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACO A:301;
Valid;
Atoms found LESS than expected: % Diff = 0;
submit data
809.571 C23 H38 N7 O17 P3 S CC(=O...
MLA A:302;
A:303;
Valid;
Valid;
none;
none;
submit data
104.061 C3 H4 O4 C(C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HGZ 1.38 Å EC: 2.3.1.48 CRYSTAL STRUCTURE OF HUMAN NAA60 IN COMPLEX WITH ACETYL-COA HOMO SAPIENS N-TERMINAL ACETYLATION COMPLEX NATS PROTEIN MODIFICAITONTRANSFERASE
Ref.: STRUCTURE AND FUNCTION OF HUMAN NAA60 (NATF), A GOLGI-LOCALIZED BI-FUNCTIONAL ACETYLTRANSFERASE SCI REP V. 6 31425 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 46 families.
1 5HGZ - MLA C3 H4 O4 C(C(=O)O)C....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 29 families.
1 5ICV ic50 = 2.44 uM MET LYS ALA VAL 1XE n/a n/a
2 5ICW - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
3 5HGZ - MLA C3 H4 O4 C(C(=O)O)C....
4 5HH0 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
5 5HH1 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 5ICV ic50 = 2.44 uM MET LYS ALA VAL 1XE n/a n/a
2 5ICW - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
3 5HGZ - MLA C3 H4 O4 C(C(=O)O)C....
4 5HH0 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
5 5HH1 - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ACO; Similar ligands found: 178
No: Ligand ECFP6 Tc MDL keys Tc
1 ACO 1 1
2 3KK 0.9 0.988636
3 CAO 0.898305 0.934066
4 COS 0.898305 0.944444
5 2MC 0.893443 0.945652
6 OXK 0.892562 0.966292
7 MC4 0.887097 0.935484
8 CO6 0.885246 0.988636
9 1VU 0.885246 0.977528
10 CAA 0.879032 0.977273
11 SOP 0.877049 0.966292
12 MLC 0.870968 0.966292
13 BCO 0.870968 0.966292
14 1HE 0.870968 0.966667
15 3HC 0.870968 0.977273
16 IVC 0.870968 0.977273
17 FYN 0.868852 0.965909
18 MCA 0.864 0.977528
19 COO 0.864 0.966292
20 COK 0.861789 0.944444
21 COA 0.857143 0.965909
22 SCA 0.857143 0.966292
23 0T1 0.857143 0.94382
24 DCA 0.855932 0.94382
25 CMC 0.854839 0.944444
26 30N 0.85124 0.885417
27 HGG 0.850394 0.966292
28 BYC 0.850394 0.966292
29 COW 0.850394 0.955556
30 IRC 0.850394 0.977273
31 1GZ 0.850394 0.955556
32 BCA 0.84375 0.955556
33 FAQ 0.84375 0.966292
34 2CP 0.84252 0.955556
35 A1S 0.84127 0.966292
36 ETB 0.840336 0.932584
37 GRA 0.837209 0.966292
38 HXC 0.837209 0.988764
39 AMX 0.836066 0.954545
40 TGC 0.830769 0.955556
41 SCO 0.829268 0.94382
42 CMX 0.829268 0.94382
43 2NE 0.824427 0.945055
44 1CZ 0.824427 0.955556
45 CO8 0.824427 0.988764
46 FAM 0.822581 0.923077
47 FCX 0.822581 0.913043
48 COF 0.821705 0.923913
49 3CP 0.821705 0.944444
50 2KQ 0.821705 0.988764
51 MYA 0.818182 0.988764
52 ST9 0.818182 0.988764
53 UCC 0.818182 0.988764
54 DCC 0.818182 0.988764
55 MFK 0.818182 0.988764
56 5F9 0.818182 0.988764
57 HAX 0.816 0.923077
58 4CA 0.815385 0.934066
59 7L1 0.814516 1
60 WCA 0.80597 0.945055
61 CS8 0.80597 0.977778
62 SCD 0.804688 0.94382
63 MCD 0.80315 0.966292
64 CA6 0.80315 0.896907
65 HDC 0.8 0.988764
66 4KX 0.8 0.934783
67 CIC 0.796992 0.944444
68 NMX 0.796875 0.875
69 MRR 0.794118 0.988764
70 MRS 0.794118 0.988764
71 4CO 0.791045 0.934066
72 0FQ 0.791045 0.944444
73 CAJ 0.790698 0.944444
74 YNC 0.788321 0.955556
75 DAK 0.788321 0.934783
76 0ET 0.785185 0.966667
77 01A 0.785185 0.904255
78 8Z2 0.782609 0.977778
79 HFQ 0.781022 0.923913
80 1CV 0.779412 0.966292
81 YE1 0.778626 0.933333
82 NHM 0.773723 0.966667
83 UOQ 0.773723 0.966667
84 NHW 0.773723 0.966667
85 CA8 0.766917 0.877551
86 F8G 0.762238 0.946237
87 1HA 0.760563 0.945055
88 NHQ 0.746479 0.955056
89 S0N 0.744526 0.923077
90 CCQ 0.744526 0.945652
91 01K 0.743056 0.966292
92 COT 0.737931 0.944444
93 CA3 0.727891 0.944444
94 UCA 0.721854 0.988764
95 CO7 0.713235 0.966292
96 CA5 0.703947 0.904255
97 93P 0.699346 0.934066
98 COD 0.692913 0.954545
99 93M 0.666667 0.934066
100 4BN 0.656627 0.946237
101 5TW 0.656627 0.946237
102 OXT 0.634731 0.946237
103 HMG 0.62585 0.933333
104 PLM COA 0.61745 0.955556
105 COA PLM 0.61745 0.955556
106 JBT 0.609195 0.926316
107 BSJ 0.594118 0.913979
108 PAP 0.577586 0.784091
109 ASP ASP ASP ILE CMC NH2 0.557576 0.902174
110 PPS 0.53719 0.729167
111 191 0.532895 0.877551
112 RFC 0.53125 0.966667
113 SFC 0.53125 0.966667
114 A3P 0.525862 0.772727
115 ACE SER ASP ALY THR NH2 COA 0.511111 0.923077
116 0WD 0.503497 0.763441
117 PTJ 0.462687 0.842697
118 3AM 0.461538 0.761364
119 3OD 0.451852 0.797753
120 A22 0.450382 0.786517
121 PUA 0.447368 0.793478
122 A2D 0.446281 0.775281
123 PAJ 0.443609 0.853933
124 SAP 0.440945 0.8
125 ATR 0.440945 0.772727
126 AGS 0.440945 0.8
127 OAD 0.437037 0.797753
128 ADP 0.435484 0.795455
129 A2R 0.431818 0.786517
130 BA3 0.427419 0.775281
131 NA7 0.426471 0.829545
132 9X8 0.426471 0.8
133 HEJ 0.425197 0.795455
134 ATP 0.425197 0.795455
135 B4P 0.424 0.775281
136 AP5 0.424 0.775281
137 ADQ 0.422222 0.777778
138 AQP 0.421875 0.795455
139 AR6 0.421875 0.775281
140 5FA 0.421875 0.795455
141 2A5 0.421875 0.818182
142 APR 0.421875 0.775281
143 48N 0.42069 0.802198
144 AN2 0.420635 0.786517
145 FYA 0.42029 0.786517
146 M33 0.417323 0.786517
147 SRP 0.413534 0.808989
148 ANP 0.412214 0.777778
149 YLB 0.412162 0.877778
150 FA5 0.411348 0.788889
151 YLP 0.410959 0.877778
152 ME8 0.410072 0.835165
153 AT4 0.409449 0.808989
154 APU 0.409396 0.76087
155 5AL 0.409091 0.786517
156 7D3 0.408 0.766667
157 F2R 0.407895 0.836957
158 NJP 0.407895 0.78022
159 AD9 0.407692 0.777778
160 25L 0.407143 0.786517
161 7D4 0.40625 0.766667
162 CA0 0.40625 0.777778
163 ATF 0.406015 0.769231
164 A A A 0.405797 0.786517
165 A2P 0.404762 0.761364
166 9ZA 0.404412 0.791209
167 8QN 0.404412 0.786517
168 9ZD 0.404412 0.791209
169 LAQ 0.40411 0.815217
170 NDP 0.403974 0.763441
171 ACP 0.403101 0.797753
172 ACQ 0.401515 0.797753
173 YAP 0.401408 0.78022
174 ATP A A A 0.401408 0.744444
175 TXA 0.4 0.788889
176 NB8 0.4 0.782609
177 PAX 0.4 0.768421
178 1ZZ 0.4 0.855556
Ligand no: 2; Ligand: MLA; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 MLA 1 1
2 AAE 0.6 0.631579
3 3OH 0.533333 0.619048
4 SIN 0.5 0.722222
5 98J 0.428571 0.608696
6 GUA 0.411765 0.65
7 0L1 0.411765 0.619048
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HGZ; Ligand: MLA; Similar sites found with APoc: 9
This union binding pocket(no: 1) in the query (biounit: 5hgz.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
1 1HG4 LPP 1.23457
2 6ADI 9UO 3.7037
3 2Z77 HE7 4.31655
4 3CF6 SP1 5.34979
5 2ZCQ B65 6.17284
6 5Y6Q FAD 6.99588
7 5WRE 7TL 7.74194
8 5K8C NAD 7.81893
9 2BIF BOG 10.6996
Pocket No.: 2; Query (leader) PDB : 5HGZ; Ligand: ACO; Similar sites found with APoc: 373
This union binding pocket(no: 2) in the query (biounit: 5hgz.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2VWA PTY None
2 5NNT DPV None
3 3RV5 DXC None
4 5CHR 4NC None
5 4I67 G G G RPC None
6 2CJW GDP None
7 3KO0 TFP None
8 3N5C GDP None
9 2GBB CIT None
10 4BQS ADP None
11 4WG0 CHD None
12 5U83 ZN8 0.943396
13 1B0U ATP 1.14504
14 3B5J 12D 1.23457
15 1DTL BEP 1.24224
16 1G8S MET 1.30435
17 2CDN ADP 1.49254
18 1XX6 ADP 1.57068
19 6CS8 F9Y 1.64609
20 2FT0 ACO 1.70213
21 1VJE MSE 1.80723
22 3P7G MAN 2.05479
23 4AVB ACO 2.05761
24 2D2F ADP 2.05761
25 5OLK DTP 2.05761
26 2O1V ADP 2.05761
27 4I90 CHT 2.05761
28 5LKT BCO 2.05761
29 1ZGS XMM 2.05761
30 4LY9 S6P 2.05761
31 4LY9 1YY 2.05761
32 6BXO SAH 2.05761
33 2EFX NFA 2.05761
34 5UC4 83S 2.27273
35 2YLD CMO 2.3622
36 4WGF HX2 2.43902
37 1JJ7 ADP 2.46914
38 5M04 GDP 2.46914
39 3WY9 GDP 2.46914
40 6CGN DA 2.46914
41 4O08 PO6 2.46914
42 5Z3I ADE 2.46914
43 5EE7 5MV 2.46914
44 2GCG DGY 2.46914
45 5YEE LAB 2.46914
46 4B1X LAB 2.46914
47 4KVX ACO 2.5641
48 5GVR LMR 2.5641
49 1SVI GDP 2.5641
50 5KTC FUH 2.65957
51 5KTC COA 2.65957
52 4RC8 STE 2.7027
53 5W8E ADE 2.71493
54 5W8E SXZ 2.71493
55 1C3M MAN MAN 2.72109
56 1M7G AV2 2.8436
57 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.88066
58 1G6H ADP 2.88066
59 2GWH PCI 2.88066
60 5TVJ 7LF 2.88066
61 5TVJ COA 2.88066
62 4YJ1 ADP 2.88066
63 4DDY DN6 2.88066
64 5NM7 GLY 2.88066
65 2XT3 ADP 2.88066
66 4DE3 DN8 2.88066
67 1SKQ GDP 2.88066
68 3LN0 52B 2.88066
69 4AG5 ADP 2.88066
70 1GEG GLC 2.88066
71 3TK1 GDP 2.88066
72 3PMA SCR 2.88066
73 1TL2 NDG 2.9661
74 2WJG GDP 3.19149
75 5MU6 MYA 3.29218
76 5MU6 KFK 3.29218
77 4U00 ADP 3.29218
78 1RJW ETF 3.29218
79 4LOC OXM 3.29218
80 1D2E GDP 3.29218
81 5NCB JZ3 3.29218
82 1S7N COA 3.2967
83 1GXU 2HP 3.2967
84 4R2I ANP 3.33333
85 1JI0 ATP 3.33333
86 1C9K 5GP 3.33333
87 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 3.34728
88 1HBK MYR 3.37079
89 1HBK COA 3.37079
90 1NF8 BOG 3.38164
91 3W5J GDP 3.43137
92 2BHW NEX 3.44828
93 2BHW XAT 3.44828
94 4B5P ACO 3.5
95 1F6B GDP 3.53535
96 6EDV COA 3.60825
97 2WPX ACO 3.7037
98 1TV5 N8E 3.7037
99 2VVG ADP 3.7037
100 3W54 RNB 3.7037
101 1GOJ ADP 3.7037
102 3COB ADP 3.7037
103 1WLJ U5P 3.7037
104 2X7I CIT 3.7037
105 2OG2 MLI 3.7037
106 3B9Q MLI 3.7037
107 4ORM ORO 3.7037
108 4ORM FMN 3.7037
109 4ORM 2V6 3.7037
110 4X8D AVI 3.7037
111 1LAN LEU 3.7037
112 3DSK T25 3.7037
113 4EIL FOL 3.7037
114 5H7J GCP 3.7037
115 5NTD BES 3.7037
116 4YMU ATP 3.75
117 4KFU ACP 3.77358
118 3G5K BB2 3.82514
119 4DD8 BAT 3.84615
120 2IYG FMN 4.03226
121 1XP8 AGS 4.09836
122 3PQC GDP 4.10256
123 2JDC CAO 4.10959
124 3D2M COA 4.11523
125 2AWN ADP 4.11523
126 1RRC ADP 4.11523
127 3LRE ADP 4.11523
128 1ZPD CIT 4.11523
129 6A20 ADP 4.11523
130 4C2X NHW 4.11523
131 5YT0 GDP 4.11523
132 2NCD ADP 4.11523
133 2WHX ADP 4.11523
134 2A9W GA9 4.11523
135 2Q4G CIT 4.11523
136 4YRY NAD 4.11523
137 3KIH GDL 4.12371
138 4OHU NAD 4.15225
139 4OHU 2TK 4.15225
140 5I8F ML1 4.24242
141 5W7B MYR 4.25532
142 4OIC A8S 4.34783
143 5UIV ADP 4.40529
144 3I6B KDO 4.44444
145 3AQT RCO 4.4898
146 1EYQ NAR 4.5045
147 1UGY GLA GLC 4.51128
148 1WS4 AMG 4.51128
149 1UGY GLA BGC 4.51128
150 1WS4 GYP 4.51128
151 1UGW GAL 4.51128
152 1M26 GAL A2G 4.51128
153 1KUJ MMA 4.51128
154 1JAC AMG 4.51128
155 1WS5 MMA 4.51128
156 1TOQ AMG 4.51128
157 3SXN COA 4.52675
158 2WSA MYA 4.52675
159 2WSA 646 4.52675
160 5EY0 GTP 4.52675
161 2Y65 ADP 4.52675
162 5XQL C2E 4.52675
163 5AZC PGT 4.52675
164 5KOD IAC 4.52675
165 1F9V ADP 4.52675
166 3U6B GDP 4.52675
167 5LTJ ADP 4.52675
168 1D8T GDP 4.52675
169 5ZI9 FLC 4.52675
170 4G5G GDP 4.52675
171 3U6K GDP 4.52675
172 5JBQ GDP 4.52675
173 2WH8 II2 4.52675
174 1YRE COA 4.56853
175 4ONT SIA GAL BGC 4.65116
176 3F8C HT1 4.7619
177 5URY PAM 4.79452
178 2VBQ BSJ 4.84848
179 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY 4.90196
180 2YNE YNE 4.93827
181 2YNE NHW 4.93827
182 4WZ6 ATP 4.93827
183 2ZFN ACO 4.93827
184 2YNC YNC 4.93827
185 4DO1 ANN 4.93827
186 4J0Q GDP 4.93827
187 3CZ7 ACO 4.93827
188 1TMX HGX 4.93827
189 2DHC DCE 4.93827
190 5W76 GDP 4.93827
191 2W58 ADP 4.9505
192 3A4M ADP 5
193 5YGE ACO 5.17241
194 5YGE GLU 5.17241
195 2HT6 GDP 5.17241
196 2PZE ATP 5.24017
197 4AKB GAL 5.26316
198 2WPW ACO 5.34979
199 2ZW5 COA 5.34979
200 2BCG GER 5.34979
201 4FRZ ADP 5.34979
202 5XDR ADP 5.34979
203 5ZXD ATP 5.34979
204 4IHQ ADP 5.34979
205 4NON GDP 5.34979
206 3KIF GDL 5.66038
207 1R6N 434 5.6872
208 2ZPA ACO 5.76132
209 4UWJ 7L5 5.76132
210 4UWJ MYA 5.76132
211 5IM3 DTP 5.76132
212 3E70 GDP 5.76132
213 6BR8 6OU 5.76132
214 5CX6 CDP 5.76132
215 1XVB 3BR 5.76132
216 6BR9 6OU 5.76132
217 1R0X ATP 5.76132
218 5W75 GDP 5.76132
219 4V3I ASP LEU THR ARG PRO 5.76132
220 1XVB BHL 5.76132
221 5N8V KZZ 5.7971
222 2IL4 COA 5.82524
223 5NTP 98E 5.88235
224 3RMK BML 6.0241
225 2HHP FLC 6.17284
226 3RC3 ANP 6.17284
227 4G86 BNT 6.17284
228 2GN2 C5P 6.17284
229 5W7Q GDP 6.17284
230 1NU4 MLA 6.18557
231 4IBF 1D5 6.20155
232 4K30 NLG 6.25
233 3LN9 FLC 6.47482
234 4O4Z N2O 6.49351
235 1LVG ADP 6.56566
236 1XQP 8HG 6.58436
237 5YV5 ADP 6.58436
238 1YQT ADP 6.58436
239 5E5U MLI 6.58436
240 5FG3 GDP 6.58436
241 1BG2 ADP 6.58436
242 1PVC ILE SER GLU VAL 6.58436
243 5ZZA LAB 6.61157
244 3H4S ADP 6.66667
245 3B6C SDN 6.83761
246 1V0C ACO 6.93069
247 1V0C KNC 6.93069
248 3N7S 3N7 6.95652
249 1T5C ADP 6.99588
250 1IID NHM 6.99588
251 1XMV ADP 6.99588
252 1KK1 GNP 6.99588
253 5OSW DIU 6.99588
254 5OSW AE4 6.99588
255 1SBR VIB 7
256 4P3Y GDP 7.14286
257 1FZQ GDP 7.18232
258 1N71 COA 7.22222
259 4DOO DAO 7.31707
260 2VZZ SCA 7.33945
261 5V3Y 5V8 7.40741
262 2XAU ADP 7.40741
263 2GDJ ANP 7.40741
264 5WL1 D3D 7.40741
265 5WL1 CUY 7.40741
266 4QM7 GTP 7.60234
267 1IYK MYA 7.81893
268 1T36 ORN 7.81893
269 5TSH ADP 7.81893
270 1OXV ANP 7.81893
271 3KPE TM3 7.84314
272 4YDS ATP 7.89474
273 4XPL ACO 7.97546
274 1ZED PNP 8.23045
275 3ETG GTP 8.23045
276 3W5N RAM 8.64198
277 3NHB ADP 8.64198
278 3BPX SAL 8.78378
279 5OCA 9QZ 8.82353
280 1SJD NPG 9.0535
281 4AG9 COA 9.09091
282 5KAU RHQ 9.09091
283 6FS0 E4W 9.17431
284 4V1F BQ1 9.30233
285 5U32 GDP 9.32203
286 5N26 CPT 9.34066
287 5LX9 OLB 9.46502
288 3EC1 GDP 9.46502
289 4CRZ ACO 9.48905
290 5LS7 ACO 9.48905
291 4QC6 30N 9.49721
292 3TE4 ACO 9.76744
293 4B47 GDP 9.87654
294 5XK9 DMA 9.91379
295 2CBZ ATP 10.1266
296 4URN NOV 10.2222
297 3TDC 0EU 10.2881
298 4PPF FLC 10.6996
299 1U0J ADP 10.6996
300 6BMS POV 10.6996
301 2WOR 2AN 11
302 3N8K D1X 11.0465
303 4URG C2E 11.1111
304 4OGQ 7PH 11.1628
305 3KP6 SAL 11.2583
306 5KF9 ACO 11.5226
307 5KF9 COA 11.5226
308 5KF9 NAG 11.5226
309 5OKL PAM 11.5226
310 1P0H COA 11.5226
311 1P0H ACO 11.5226
312 3GD8 GOL 11.6592
313 4XCP PLM 11.7647
314 4MA7 P2Z 11.9266
315 3BOS CDP 11.9835
316 4U9W COA 12.0773
317 1I4D GDP 12.5
318 4UUJ XA7 13.242
319 3WR7 COA 13.5294
320 3ZJ0 ACO 13.5922
321 4RJD TFP 13.6364
322 3R96 AMP 13.8298
323 3R96 ACO 13.8298
324 1TIQ COA 13.8889
325 1MKY GDP 13.9918
326 4H6U ACO 14
327 2KIN ADP 14
328 2Y69 CHD 14.5374
329 1RE0 GDP 15.2439
330 1S9D GDP 15.2439
331 2X77 GDP 15.3439
332 1CM0 COA 15.4762
333 2Q4V ACO 15.8824
334 4UA3 COA 15.9794
335 2HCJ GDP 16.2162
336 1GHE ACO 16.3842
337 6G96 ACO 16.4773
338 1WWZ ACO 16.8724
339 2GKS ADP 16.8724
340 5M36 9SZ 17.0306
341 4R57 ACO 17.0455
342 2B4B COA 17.5439
343 2B4D COA 17.5439
344 2ZR9 DTP 18.107
345 2JEV NHQ 18.3908
346 1PUA COA 19.0184
347 1QSR ACO 19.1358
348 1Q2D COA 19.1358
349 1QSN COA 19.1358
350 1Q2C COA 19.1358
351 5Z84 CHD 19.1489
352 5ZCO CHD 19.1489
353 5W97 CHD 19.1489
354 5FVJ ACO 19.2771
355 5XJ7 87O 19.9005
356 5JPH COA 20.1389
357 1KUV CA5 20.2899
358 4RI1 ACO 20.4301
359 2QN6 GDP 20.4301
360 5K04 COA 20.5882
361 1M4I KAN 21.547
362 1M4I COA 21.547
363 1M4I PAP 21.547
364 1I1D COA 22.3602
365 1I1D 16G 22.3602
366 4KOT CE3 23.4568
367 2CNT COA 25
368 1CJW COT 25.3012
369 3F8K COA 26.875
370 1BO4 COA 27.381
371 5XXS COA 29.5455
372 4R3L COA 39.8844
373 3K9U ACO 42.1384
Pocket No.: 3; Query (leader) PDB : 5HGZ; Ligand: MLA; Similar sites found with APoc: 101
This union binding pocket(no: 3) in the query (biounit: 5hgz.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1W4R TTP None
2 4UXH T5A None
3 1PZG A3D None
4 3ZZL TRP None
5 4H6Q TFB 1.23457
6 4H6Q FAD 1.23457
7 1C96 FLC 1.64609
8 2B8T THM 1.79372
9 4XBA GMP 2
10 2O3Z AI7 2.05761
11 5ETJ IM5 2.05761
12 2IXE ATP 2.05761
13 2AKO ADP 2.46914
14 5G4L NDP 2.46914
15 5AE9 OKO 2.46914
16 1X87 NAD 2.46914
17 1EQ2 ADQ 2.46914
18 2F5X ASP 2.88066
19 4C3Y ANB 2.88066
20 4C3Y FAD 2.88066
21 4KX8 L2O VAL VAL ASP 2.88066
22 4KCF FMN 2.88066
23 3WRB GDE 2.88066
24 4HGD KGT 2.88066
25 1GV0 NAD 2.88066
26 3EAU NDP 2.88066
27 3EAU PDN 2.88066
28 4R6W SAH 3.29218
29 4R6W PC 3.29218
30 3CRZ NAP 3.29218
31 1TED MYR 3.29218
32 2G37 FAD 3.29218
33 4XT8 TMQ 3.29218
34 4XT8 NAP 3.29218
35 4MFZ MFK 3.29218
36 5FUW QBT 3.2967
37 5FUW THM 3.2967
38 5WP4 SAH 3.7037
39 2Z4T C5P 3.7037
40 3VZS NAP 3.7037
41 2O0J ADP 3.7037
42 5L9G MO0 3.7037
43 6C90 ADP 3.7037
44 2QQ0 THM 3.80435
45 2QQ0 ADP 3.80435
46 2QQ0 TMP 3.80435
47 4P86 5GP 3.82514
48 3QF7 ANP 4
49 2B9W FAD 4.00943
50 5AB0 2X0 7GA LYS HIS HIS ALA PHE SER PHE LYN 4.11523
51 1RHC F42 ACN 4.11523
52 4P5F AR6 4.11523
53 2IV2 2MD 4.11523
54 2RIF AMP 4.25532
55 2TPS TPS 4.40529
56 5YIC 8VO 4.52675
57 4Q3S X7A 4.52675
58 1U1I NAD 4.52675
59 4ZOH MCN 4.7619
60 1NJF AGS 4.93827
61 1ZUA NAP 4.93827
62 1ZUA TOL 4.93827
63 1L5J TRA 4.93827
64 5JSJ 6PD 4.95496
65 5CC2 CKA 5.34979
66 5E2N V14 5.34979
67 5L44 K26 5.34979
68 1FRB ZST 5.76132
69 4TWL ASC 5.76132
70 5WX3 COA 5.76132
71 2HJR APR 5.76132
72 4E3Q PMP 6.17284
73 4K30 NLG 6.25
74 3AI8 HNQ 6.58436
75 2QZZ NAP 6.99588
76 2QZZ EMF 6.99588
77 2UZ2 BTN 7.69231
78 5NQR 958 7.76256
79 9LDB NAD 7.81893
80 9LDT NAD 7.81893
81 4EU7 CIT 8.64198
82 4BJ8 BTN 8.73016
83 1UVC STE 8.79121
84 1TIP F6P 8.90052
85 1KQF MGD 9.0535
86 1W2T SUC GLA 9.46502
87 1KEV NDP 9.46502
88 4V3C C 9.46502
89 4QC6 30N 9.49721
90 5A4W QCT 9.90566
91 1LDN NAD 11.9342
92 3UKR CKH 12.5
93 3R96 ACO 13.8298
94 3R96 AMP 13.8298
95 5VN0 FAD 14.8148
96 5VN0 NAI 14.8148
97 5CLO NS8 15.2542
98 3LF0 ATP 15.7895
99 5XJ7 87O 19.9005
100 4KOT CE3 23.4568
101 2QRD ATP 25.7732
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