Receptor
PDB id Resolution Class Description Source Keywords
5HA0 1.44 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE LTBP1 LEUKOTRIENE D4 COMPLEX RHODNIUS PROLIXUS LIPOCALIN LEUKOTRIENE RHODNIUS SALIVARY TRANSPORT PROTEI
Ref.: STRUCTURE AND LIGAND-BINDING MECHANISM OF A CYSTEIN LEUKOTRIENE-BINDING PROTEIN FROM A BLOOD-FEEDING DI VECTOR. ACS CHEM.BIOL. V. 11 1934 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LTD A:201;
Valid;
none;
Kd < 1 nM
496.66 C25 H40 N2 O6 S CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HA0 1.44 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE LTBP1 LEUKOTRIENE D4 COMPLEX RHODNIUS PROLIXUS LIPOCALIN LEUKOTRIENE RHODNIUS SALIVARY TRANSPORT PROTEI
Ref.: STRUCTURE AND LIGAND-BINDING MECHANISM OF A CYSTEIN LEUKOTRIENE-BINDING PROTEIN FROM A BLOOD-FEEDING DI VECTOR. ACS CHEM.BIOL. V. 11 1934 2016
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 5HAE - EAH C20 H32 O3 CCCCCC=C/C....
2 5HA0 Kd < 1 nM LTD C25 H40 N2 O6 S CCCCC/C=CC....
3 5H9L - EAH C20 H32 O3 CCCCCC=C/C....
4 5H9N Ka = 21000000 M^-1 LTX C30 H47 N3 O9 S CCCCC/C=CC....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 5HAE - EAH C20 H32 O3 CCCCCC=C/C....
2 5HA0 Kd < 1 nM LTD C25 H40 N2 O6 S CCCCC/C=CC....
3 5H9L - EAH C20 H32 O3 CCCCCC=C/C....
4 5H9N Ka = 21000000 M^-1 LTX C30 H47 N3 O9 S CCCCC/C=CC....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 5HAE - EAH C20 H32 O3 CCCCCC=C/C....
2 5HA0 Kd < 1 nM LTD C25 H40 N2 O6 S CCCCC/C=CC....
3 5H9L - EAH C20 H32 O3 CCCCCC=C/C....
4 5H9N Ka = 21000000 M^-1 LTX C30 H47 N3 O9 S CCCCC/C=CC....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: LTD; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 LTD 1 1
2 LTX 0.714286 1
Similar Ligands (3D)
Ligand no: 1; Ligand: LTD; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HA0; Ligand: LTD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5ha0.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
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