Receptor
PDB id Resolution Class Description Source Keywords
5GZ9 2.4 Å EC: 2.7.1.- CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF PROTEIN O-MANNOSYL COMPLEXES WITH AMP-PNP, MAGNESIUM IONS AND GLYCOPEPTIDE MUS MUSCULUS SUGAR KINASE DYSTROGLYCANOPATHY O-MANNOSYLATION TRANSFERA
Ref.: 3D STRUCTURAL ANALYSIS OF PROTEIN O-MANNOSYL KINASE CAUSATIVE GENE PRODUCT OF DYSTROGLYCANOPATHY. GENES CELLS 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:1001;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:1003;
A:1002;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
MAN A:1004;
Valid;
none;
submit data
180.156 C6 H12 O6 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5GZ9 2.4 Å EC: 2.7.1.- CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF PROTEIN O-MANNOSYL COMPLEXES WITH AMP-PNP, MAGNESIUM IONS AND GLYCOPEPTIDE MUS MUSCULUS SUGAR KINASE DYSTROGLYCANOPATHY O-MANNOSYLATION TRANSFERA
Ref.: 3D STRUCTURAL ANALYSIS OF PROTEIN O-MANNOSYL KINASE CAUSATIVE GENE PRODUCT OF DYSTROGLYCANOPATHY. GENES CELLS 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5GZ9 - MAN C6 H12 O6 C([C@@H]1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5GZA Kd = 30.2 uM MAN NAG NGA n/a n/a
2 5GZ9 - MAN C6 H12 O6 C([C@@H]1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5GZA Kd = 30.2 uM MAN NAG NGA n/a n/a
2 5GZ9 - MAN C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Ligand no: 2; Ligand: MAN; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL 1 1
2 BMA 1 1
3 GXL 1 1
4 GLA 1 1
5 ALL 1 1
6 GLC 1 1
7 BGC 1 1
8 GIV 1 1
9 MAN 1 1
10 WOO 1 1
11 32O 0.653846 0.866667
12 RIB 0.653846 0.866667
13 FUB 0.653846 0.866667
14 Z6J 0.653846 0.866667
15 AHR 0.653846 0.866667
16 BMA BMA MAN 0.545455 0.823529
17 GLA BGC 0.511628 0.848485
18 LAK 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 GLA GLC 0.511628 0.848485
23 GAL GAL 0.511628 0.848485
24 MLB 0.511628 0.848485
25 BMA GLA 0.511628 0.848485
26 BMA BMA BMA BMA BMA BMA MAN 0.5 0.823529
27 YDR 0.5 0.8
28 MAN BMA BMA BMA BMA BMA 0.5 0.823529
29 GLC GLC GLC GLC BGC 0.488889 0.848485
30 GLC GLC GLC 0.488889 0.848485
31 MAN MAN MAN 0.488889 0.848485
32 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
33 BGP 0.461538 0.675
34 G6P 0.461538 0.675
35 M6P 0.461538 0.675
36 A6P 0.461538 0.675
37 M6D 0.461538 0.675
38 BG6 0.461538 0.675
39 SHG 0.457143 0.875
40 GAF 0.457143 0.875
41 G2F 0.457143 0.875
42 X6X 0.457143 0.777778
43 2FG 0.457143 0.875
44 G3F 0.457143 0.875
45 PA1 0.457143 0.777778
46 1GN 0.457143 0.777778
47 GCS 0.457143 0.777778
48 2H5 0.457143 0.875
49 LB2 0.454545 0.848485
50 BGC BMA 0.454545 0.848485
51 BGC GAL 0.454545 0.848485
52 MAL 0.454545 0.848485
53 GLC GAL 0.454545 0.848485
54 M3M 0.454545 0.848485
55 GLA GAL 0.454545 0.848485
56 MAB 0.454545 0.848485
57 GLC BGC 0.454545 0.848485
58 BMA BMA 0.454545 0.848485
59 LBT 0.454545 0.848485
60 MAL MAL 0.454545 0.823529
61 CBK 0.454545 0.848485
62 GLA GLA 0.454545 0.848485
63 MAN GLC 0.454545 0.848485
64 CBI 0.454545 0.848485
65 N9S 0.454545 0.848485
66 GAL GLC 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 B2G 0.454545 0.848485
69 BGC GLC 0.454545 0.848485
70 LAT 0.454545 0.848485
71 GAL BGC 0.454545 0.848485
72 3MG 0.444444 0.875
73 TCB 0.444444 0.8
74 GLC SGC 0.444444 0.8
75 YIO 0.441176 0.870968
76 2GS 0.432432 0.875
77 BGC BGC 0.431818 0.848485
78 2M4 0.431818 0.848485
79 MAN MAN 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 CT3 0.416667 0.848485
84 GLC BGC GLC 0.416667 0.848485
85 MLR 0.416667 0.848485
86 GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
87 GLC GLC GLC GLC GLC 0.416667 0.848485
88 GAL FUC 0.416667 0.848485
89 BMA BMA BMA 0.416667 0.848485
90 CTR 0.416667 0.848485
91 BGC GLC GLC 0.416667 0.848485
92 BGC GLC GLC GLC GLC 0.416667 0.848485
93 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
94 GLC GAL GAL 0.416667 0.848485
95 B4G 0.416667 0.848485
96 CEX 0.416667 0.848485
97 MAN BMA BMA BMA BMA 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
100 CTT 0.416667 0.848485
101 GLC GLC BGC 0.416667 0.848485
102 DXI 0.416667 0.848485
103 GLC GLC BGC GLC GLC GLC GLC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
107 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
108 MTT 0.416667 0.848485
109 BMA MAN BMA 0.416667 0.848485
110 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
111 CE5 0.416667 0.848485
112 GAL GAL GAL 0.416667 0.848485
113 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
114 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
115 GLA GAL GLC 0.416667 0.848485
116 CE6 0.416667 0.848485
117 GLC BGC BGC BGC BGC 0.416667 0.848485
118 GLC BGC BGC 0.416667 0.848485
119 MAN BMA BMA 0.416667 0.848485
120 MT7 0.416667 0.848485
121 GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
122 CE8 0.416667 0.848485
123 CEY 0.416667 0.848485
124 BGC BGC BGC 0.408163 0.848485
125 BGC BGC BGC BGC BGC 0.408163 0.848485
126 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
127 SGC SGC BGC 0.408163 0.8
128 GLC BGC BGC BGC 0.408163 0.848485
129 BGC BGC BGC ASO BGC BGC ASO 0.408163 0.848485
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 TRE 0.405405 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 BM3 0.404762 0.7
135 NDG 0.404762 0.7
136 NAG 0.404762 0.7
137 HSQ 0.404762 0.7
138 A2G 0.404762 0.7
139 NGA 0.404762 0.7
140 FUB AHR AHR 0.4 0.764706
141 AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5GZ9; Ligand: ANP; Similar sites found: 362
This union binding pocket(no: 1) in the query (biounit: 5gz9.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3OID TCL 0.007779 0.43178 1.16279
2 2PVN P63 0.00000001877 0.57051 1.31148
3 5MY8 RXZ 0.000003681 0.51377 1.63934
4 3W0O ADP 0.0002859 0.42033 1.63934
5 3W0O HY0 0.0002859 0.42033 1.63934
6 2YRX AMP 0.01635 0.41617 1.63934
7 1U6R IOM 0.01784 0.41299 1.63934
8 2YAB AMP 0.0000001349 0.61155 1.96721
9 5LXC 7AA 0.000000007537 0.5835 1.96721
10 3TDV GDP 0.0000009866 0.58088 1.96721
11 5CKW ANP 0.0001957 0.50082 1.96721
12 4GLW 0XT 0.01102 0.41934 1.96721
13 4WA2 SIA GAL NAG 0.02222 0.40813 1.96721
14 1VRP IOM 0.02633 0.40075 1.96721
15 3M2W L8I 0.00000006219 0.66181 2.00669
16 5AWM ANP 0.00000004116 0.68079 2.29508
17 4JDI ANP 0.000000003248 0.67325 2.29508
18 4IDT T28 0.00000001563 0.67044 2.29508
19 3ALN ANP 0.00000000773 0.65714 2.29508
20 2F57 23D 0.000001671 0.5855 2.29508
21 4IZY 1J2 0.0000004635 0.58108 2.29508
22 3Q60 ATP 0.000001885 0.57549 2.29508
23 5MW8 ATP 0.0000007001 0.56053 2.29508
24 4I6H 1C8 0.00004027 0.50899 2.29508
25 2VPQ ANP 0.0003244 0.45096 2.29508
26 3VOT ADP 0.002946 0.44316 2.29508
27 1PK8 ATP 0.0003612 0.43703 2.29508
28 3TII ANP 0.005326 0.43054 2.29508
29 5C1P ADP 0.004612 0.42912 2.29508
30 3E7O 35F 0.00005244 0.42861 2.29508
31 1SR9 KIV 0.03193 0.40108 2.29508
32 4BCQ TJF 0.00000031 0.63788 2.32558
33 4BCM T7Z 0.000002723 0.60993 2.32558
34 4BCN T9N 0.0000000653 0.6608 2.33333
35 5LMK 6ZK 0.000003591 0.56999 2.3569
36 2X4Z X4Z 0.000001133 0.47965 2.36486
37 4OCJ NDG 0.000006272 0.44288 2.37467
38 4ZGP ADP 0.01135 0.40296 2.38908
39 3UDZ ADP 0.000000314 0.5521 2.43408
40 3VPC ADP 0.0005558 0.44526 2.48227
41 4H3Q ANP 0.000000001516 0.67004 2.48619
42 4H3P ANP 0.00000008606 0.62815 2.48619
43 5BVE 4VG 0.0000001189 0.40597 2.49307
44 1RE8 BD2 0.00000006832 0.64386 2.62295
45 4IJP 1EH 0.00000007888 0.5831 2.62295
46 4AUA 4AU 0.000001296 0.58292 2.62295
47 4U44 3D9 0.0000003686 0.54184 2.62295
48 4WNK 453 0.0000001302 0.53655 2.62295
49 3WVR AMP 0.00005033 0.51648 2.62295
50 3MVH WFE 0.0000004037 0.51629 2.62295
51 4IX4 ADP 0.00002953 0.4832 2.62295
52 4U98 ACP 0.0007398 0.45716 2.62295
53 3AKK ADP 0.0005407 0.45415 2.62295
54 2VQD AP2 0.0006476 0.44651 2.62295
55 3X01 AMP 0.006168 0.4384 2.62295
56 5EKO N17 0.001002 0.43082 2.62295
57 5DZT AMP 0.01272 0.42078 2.62295
58 3VO1 FAD 0.01048 0.40819 2.62295
59 2JDR L20 0.0000003558 0.40702 2.62295
60 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.0000003558 0.40702 2.62295
61 1W2D ADP 0.005133 0.43133 2.64151
62 2O1C PPV 0.04269 0.40236 2.66667
63 5DEY 59T 0.00003861 0.41331 2.6936
64 5VC5 96M 0.0000002377 0.54005 2.76817
65 4WNP 3RJ 0.00000002566 0.68018 2.78746
66 4YZC STU 0.00000003313 0.64368 2.95082
67 5AX9 4KT 0.00000008005 0.62955 2.95082
68 3IGO ANP 0.00000002708 0.62605 2.95082
69 3UIM ANP 0.0000001446 0.61809 2.95082
70 3OFM 4B0 0.0000009412 0.60545 2.95082
71 3F7Z 34O 0.0000008662 0.5834 2.95082
72 4NM5 ADP 0.000001563 0.54619 2.95082
73 5I35 ANP 0.00001245 0.53809 2.95082
74 3E8N VRA 0.00000001522 0.47863 2.95082
75 3E8N ATP 0.00000001522 0.47863 2.95082
76 4OYA 1VE 0.00732 0.43191 2.95082
77 3DNT ATP 0.0014 0.42022 2.95082
78 4RDL FUC GAL NDG FUC 0.02924 0.40474 2.95082
79 3U6W KIV 0.02984 0.40268 2.95082
80 1ZY5 ANP 0.000107 0.49547 2.9703
81 2BPM 529 0.0000002606 0.43729 3.01887
82 3TM0 ANP 0.0005437 0.40281 3.04183
83 3IDB ANP 0.00000007018 0.60159 3.10559
84 5W2I I3P 0.002163 0.4113 3.11284
85 5W2I ADP 0.002163 0.4113 3.11284
86 4XMF HSM 0.001382 0.45356 3.26087
87 4L9I 8PR 0.00001108 0.54041 3.27869
88 3FHR P4O 0.000009126 0.53159 3.27869
89 2PYW ADP 0.00001043 0.52322 3.27869
90 4NFN 2KC 0.0001047 0.4959 3.27869
91 2JLD AG1 0.0000006392 0.49312 3.27869
92 5C4L 4XR 0.0001312 0.47993 3.27869
93 4BTK DTQ 0.0000386 0.47032 3.27869
94 5C4L SIS 0.0004893 0.45559 3.27869
95 5IQD GNP 0.001364 0.44323 3.27869
96 5IQD RIO 0.001454 0.44323 3.27869
97 5TDF ADP 0.001406 0.4321 3.27869
98 4AZW ATP 0.00305 0.41769 3.27869
99 2IO8 ADP 0.001876 0.41463 3.27869
100 3SLS ANP 0.000000009475 0.64517 3.28947
101 1PHK ATP 0.000000003127 0.62797 3.3557
102 4XV1 904 0.000002415 0.46819 3.42466
103 1S9D AFB 0.009319 0.41861 3.44828
104 4CQE CQE 0.00001674 0.50903 3.59712
105 4UX9 ANP 0.000000000229 0.72252 3.60656
106 2Z7R STU 0.000000004212 0.65993 3.60656
107 3HZT J60 0.000002325 0.59504 3.60656
108 2WU6 DKI 0.0000001156 0.59268 3.60656
109 3TTI KBI 0.000000008188 0.59184 3.60656
110 4NW6 2NS 0.000000009083 0.55573 3.60656
111 3PE2 E1B 0.00000687 0.55457 3.60656
112 4ZS4 ATP 0.000003005 0.55267 3.60656
113 3PTG 932 0.0000002996 0.50355 3.60656
114 4G17 0VN 0.0001784 0.42879 3.60656
115 3ORQ ADP 0.003235 0.4166 3.60656
116 4WHZ 3NL 0.000002989 0.40888 3.60656
117 2ZYI STE 0.003929 0.40641 3.60656
118 3HQP OXL 0.02588 0.40294 3.60656
119 1TQP ATP 0.00009183 0.46716 3.90071
120 4OUC 5ID 0.0000000242 0.67131 3.93443
121 4Y0X ADP 0.0000005609 0.60761 3.93443
122 4R78 AMP 0.00004828 0.53783 3.93443
123 2PZI AXX 0.00002593 0.53665 3.93443
124 4LOO SB4 0.00006508 0.49969 3.93443
125 3PDT ADP 0.00001261 0.54453 4
126 3HAV ATP 0.02374 0.40705 4.01338
127 3LA3 2FT 0.02569 0.40752 4.11523
128 2AQX ATP 0.002333 0.41913 4.15225
129 2WEI VGG 0.000002834 0.57479 4.18118
130 2GQR ADP 0.0003136 0.42484 4.21941
131 1U5R ATP 0.000000001232 0.71045 4.2623
132 3C0G 3AM 0.0000004181 0.62228 4.2623
133 4OTH DRN 0.0000001611 0.59358 4.2623
134 3ORK AGS 0.00000008425 0.57708 4.2623
135 5UKL SIX 0.000002016 0.55098 4.2623
136 4OCV ANP 0.00000581 0.54016 4.2623
137 3PVW QRX 0.000000649 0.5345 4.2623
138 2PUL ACP 0.00002458 0.52462 4.2623
139 1CKN GTP 0.01718 0.40959 4.2623
140 3SZB I1E 0.02408 0.40208 4.2623
141 2QX0 PH2 0.009451 0.43199 4.40252
142 4X7Q 3YR 0.00000002496 0.65214 4.59016
143 3VHE 42Q 0.000001947 0.49037 4.59016
144 5BYZ 4WE 0.000001624 0.48898 4.59016
145 4ASE AV9 0.00001354 0.47376 4.59016
146 2IF8 ADP 0.001663 0.46638 4.59016
147 4AG8 AXI 0.000001874 0.45777 4.59016
148 5VZ0 ADP 0.000787 0.45594 4.59016
149 5D1R 56S 0.01456 0.40516 4.60251
150 2NGR AF3 0.01375 0.41897 4.70085
151 1TZD ADP 0.001899 0.46765 4.72727
152 2YAK OSV 0.000001133 0.50446 4.91228
153 5LI9 ACP 0.000000007452 0.66648 4.91803
154 5DBX ANP 0.0000001047 0.65101 4.91803
155 1OBD ATP 0.0009276 0.46243 4.91803
156 5JKG 6LF 0.00002865 0.41993 4.91803
157 4A4X JUP 0.000003792 0.50599 5.01792
158 5MG2 7M8 0.02282 0.40334 5.10949
159 5X8I SQZ 0.00000001367 0.66381 5.2459
160 4CLI 5P8 0.000001231 0.58499 5.2459
161 3GC8 B45 0.000003308 0.53856 5.2459
162 1I7L ATP 0.0005489 0.43561 5.2459
163 5LUN OGA 0.01419 0.40962 5.2459
164 1EHI ADP 0.005689 0.40945 5.2459
165 2RIO ADP 0.0000000004421 0.74108 5.57377
166 1Q8Y ADP 0.0000000006584 0.7029 5.57377
167 4BFM ANP 0.0000000007316 0.70095 5.57377
168 1Q8Y ADE 0.000001904 0.6083 5.57377
169 4WOV 3SM 0.000007472 0.56246 5.57377
170 5C03 AGS 0.00001362 0.53 5.57377
171 3KN5 ANP 0.000003007 0.4892 5.57377
172 4CRL C1I 0.000002856 0.4646 5.57377
173 3WXL ADP 0.0119 0.42732 5.57377
174 3TTM PUT 0.02126 0.40025 5.57377
175 5JZJ AN2 0.00000000008292 0.77424 5.72391
176 1ZTH ADP 0.000006581 0.57293 5.81395
177 3RE4 TO1 0.00001253 0.55924 5.81395
178 1ZP9 ATP 0.00001322 0.54357 5.81395
179 2QCS ANP 0.000000002943 0.62079 5.84192
180 2CFM AMP 0.005039 0.43173 5.90164
181 5A6N U7E 0.0000006769 0.54012 6.00707
182 4CFU 2WC 0.0000000253 0.67041 6.10687
183 4FE2 ADP 0.00009525 0.50966 6.22951
184 4LH7 1X8 0.002003 0.46966 6.22951
185 4L3L 5FI 0.000002548 0.55084 6.25
186 1YRO UDP 0.01786 0.41046 6.50407
187 3BP1 GUN 0.01865 0.42498 6.55172
188 3I0O ADP 0.00004078 0.53416 6.55738
189 1IA9 ANP 0.000009858 0.53013 6.78571
190 5VCV 1N1 0.0000001727 0.57415 6.88525
191 4XYM A12 0.001914 0.43016 6.95652
192 2X2M X2M 0.00000001075 0.64288 7.21311
193 3TXO 07U 0.0000002773 0.62189 7.21311
194 2J5V PCA 0.01432 0.4204 7.21311
195 4O4F ATP 0.002723 0.40323 7.25806
196 4Y85 499 0.0000119 0.53899 7.54098
197 5W4W 9WG 0.00007529 0.43495 7.54098
198 4KBA 1QM 0.0002436 0.43184 7.54098
199 3ZJX BOG 0.003744 0.45034 7.61246
200 5N1X 8HH 0.002169 0.44001 7.62712
201 1JQY A32 0.02784 0.40302 7.76699
202 3AQV TAK 0.0006776 0.42086 7.97101
203 5TH5 MET 0.02846 0.40252 7.98479
204 4UWH JXM 0.0113 0.40665 8.52459
205 4JR7 GNP 0.000000008539 0.67293 8.85246
206 5T8O 76Z 0.0000001693 0.59979 8.85246
207 4XH0 ADP 0.00006091 0.54408 8.85246
208 4GYI ADP 0.0001434 0.50118 8.85246
209 4PU5 ANP 0.001322 0.42587 8.85246
210 2GQS ADP 0.0002224 0.48098 8.86076
211 5M06 ADP 0.000002744 0.57544 9.05797
212 4OAV ACP 0.0000001375 0.62737 9.18033
213 2WEL K88 0.000007979 0.59135 9.18033
214 3DLS ADP 0.000000205 0.53336 9.18033
215 2VN9 GVD 0.00000009341 0.67402 9.30233
216 5K2M ADP 0.0006545 0.44031 9.43396
217 4LRJ ANP 0.0000001231 0.62956 9.46746
218 2BKK ADP 0.0002851 0.48691 9.46746
219 4YLL 4E3 0.00000009387 0.5964 9.83607
220 3CY2 MB9 0.0000006168 0.56279 9.83607
221 4N70 2HX 0.0000005922 0.42897 9.83607
222 3DAK ANP 0.000002155 0.58034 10
223 5F90 GLA GAL BGC 5VQ 0.02838 0.40079 10.2564
224 1V0O INR 0.0000000126 0.65651 10.4167
225 5IH9 6BF 0.0000144 0.44155 10.4918
226 3GNI ATP 0.000000002542 0.6778 10.8197
227 3FHI ANP 0.000000001903 0.62623 11.039
228 2R5T ANP 0.00000002688 0.62619 11.1475
229 4Y8D 49J 0.0000004986 0.5941 11.4286
230 4FF8 14S 0.00003898 0.43624 11.4754
231 4AU8 Z3R 0.0000007042 0.62044 11.4865
232 1UNH IXM 0.00000001851 0.68695 11.6438
233 3O0G 3O0 0.0000002433 0.53856 11.6438
234 1K3A ACP 0.000003369 0.57899 11.7057
235 5DMZ ADP 0.000000000511 0.7275 11.8033
236 1CM8 ANP 0.0000034 0.56381 12.1311
237 1P0Z FLC 0.007824 0.43525 12.2137
238 2ZV2 609 0.0000001063 0.66063 12.4161
239 4O1P ANP 0.00000002212 0.58881 12.7869
240 2OO8 RAJ 0.00211 0.42096 12.7869
241 3LXK MI1 0.00000003399 0.57112 13.1148
242 4F9C 0SX 0.00000001516 0.67104 13.4426
243 5HVJ ANP 0.00000005505 0.70686 13.7705
244 4Q5H ANP 0.00002416 0.51889 13.7931
245 4C2V YJA 0.0000006546 0.51117 14.0351
246 1JPA ANP 0.0000001176 0.66441 14.0984
247 4C2W ANP 0.00000008658 0.66499 14.3369
248 4FL3 ANP 0.00000001189 0.64103 14.4262
249 5EOB 5QQ 0.0000003276 0.6231 14.4262
250 4CYI ATP 0.000006009 0.53347 14.4262
251 5JFS 6K0 0.0000005656 0.45389 14.4262
252 3C1X CKK 0.0007701 0.43932 14.4262
253 2Y6O 1N1 0.000003989 0.53515 14.433
254 3LXN MI1 0.0000000004829 0.70866 14.7541
255 2V7O DRN 0.0000001951 0.65797 14.7541
256 3HMO STU 0.0000002023 0.61971 14.7541
257 5N87 N66 0.0000004995 0.47914 14.7541
258 4YMJ 4EJ 0.0000001932 0.676 14.8026
259 4WW7 AMP 0.0001141 0.4741 14.9733
260 5EYK 5U5 0.00000136 0.51328 15.2174
261 4GJ3 0XP 0.00000002348 0.54929 15.2318
262 4AT3 LTI 0.000007121 0.47307 15.3846
263 2QLU ADE 0.0000000002612 0.86888 15.7377
264 4D2S DYK 0.000001708 0.59308 15.8451
265 4CS9 AMP 0.009702 0.41575 15.873
266 2XVD AS6 0.000000731 0.51622 16.2252
267 2WQN ADP 0.00000006043 0.66241 16.3934
268 3GQI ACP 0.00000002188 0.65469 16.3934
269 5U6C 7YS 0.0000004901 0.57333 16.3934
270 3GC0 AMP 0.00001546 0.54739 16.3934
271 5UR1 YY9 0.000002892 0.43292 16.3934
272 5JGA 6KC 0.0000000563 0.52509 16.7213
273 5DH3 5BS 0.00000001911 0.64032 17.0492
274 5HES 032 0.000001057 0.54556 17.0492
275 4BKJ STI 0.001103 0.41723 17.0492
276 5DRB 5FJ 0.000005229 0.41782 17.1821
277 3KRR DQX 0.00000007806 0.4049 17.2881
278 2B9J ADP 0.00000001086 0.67765 17.377
279 2B9I ADP 0.00000001566 0.66117 17.377
280 2B9F ADP 0.00000001713 0.65943 17.377
281 2B9H ADP 0.00000002926 0.59145 17.377
282 4QMN DB8 0.000004734 0.45076 17.4194
283 5LVP ATP 0.00000004487 0.66858 17.7049
284 5EFQ ADP 0.00000001262 0.66535 17.7049
285 4P5Z Q7M 0.000002044 0.45173 17.7049
286 1U59 STU 0.00000008619 0.62812 17.77
287 5G1X ADP 0.000000004731 0.69412 18.2456
288 5L8L ADP 0.00000007532 0.66795 18.2456
289 2VZ6 FEF 0.00000002595 0.67994 18.3607
290 4M69 ANP 0.00000001831 0.64111 18.3607
291 5LXM ADP 0.000000004197 0.69649 18.3746
292 3GGF GVD 0.00000004922 0.65693 18.9369
293 5CEO 50D 0.00000139 0.51898 19
294 4OH4 ANP 0.000000006143 0.67931 19.0164
295 5LPZ ADP 0.000000009648 0.67056 19.0164
296 5UIU 8CG 0.00000001522 0.6451 19.0164
297 2HY0 306 0.000001938 0.59046 19.0164
298 3TKI S25 0.0000005423 0.41714 19.0164
299 5USZ SKE 0.00000005677 0.56325 19.0311
300 3PP0 03Q 0.0000001481 0.55521 19.3443
301 5NKB 8ZT 0.0000008163 0.44451 19.3443
302 3E5A VX6 0.000001118 0.53362 19.403
303 5KO1 6UY 0.0000003839 0.60702 19.4346
304 5LPB ADP 0.00000000256 0.73983 19.5946
305 4NST ADP 0.00000002373 0.65312 19.6721
306 5HQ0 LZ9 0.000000004834 0.66586 20.8609
307 5MJA 7O3 0.0000006396 0.60495 20.9836
308 3VRY B43 0.0000003047 0.55348 20.9836
309 3BU5 ATP 0.00000000384 0.68842 21.9672
310 3EKK GS2 0.0000004692 0.47553 21.9672
311 2OFV 242 0.000001355 0.46326 22.0217
312 3SRV S19 0.0000000003874 0.7437 22.3827
313 4K33 ACP 0.00000000527 0.67305 22.623
314 3RI1 3RH 0.0000003373 0.54521 23.2787
315 2PVF ACP 0.000000007349 0.68539 23.6066
316 2HK5 1BM 0.0000004957 0.57983 23.7037
317 4E1Z 0MX 0.0000002489 0.57899 23.7113
318 3OKA GDD 0.01669 0.40615 23.8095
319 4I94 ANP 0.0000003362 0.60965 24
320 5TA6 79D 0.00003589 0.46371 24.2623
321 5FBN 5WF 0.0000002848 0.49425 24.3542
322 4Y93 746 0.000001178 0.53278 24.918
323 3SXF BK5 0.000002244 0.46458 24.918
324 3ZRM ZRM 0.000002721 0.56121 25
325 5H2U 1N1 0.00001181 0.53276 25.0936
326 5TO8 7FM 0.000003383 0.43745 25.1773
327 5DA3 58V 0.00000001909 0.69712 25.283
328 2H8H H8H 0.00000001616 0.66057 26.5574
329 3V8S 0HD 0.00000004556 0.64925 26.5574
330 1Y57 MPZ 0.000001108 0.55234 26.5574
331 3VPB ADP 0.00008545 0.46181 26.7857
332 4BHN BH9 0.00000001542 0.64431 26.8852
333 4EUU BX7 0.0000002502 0.5489 26.8852
334 1BYG STU 0.000000001348 0.72984 26.9784
335 5HX8 66P 0.000000009919 0.60064 27.1523
336 4QTB 38Z 0.000000007372 0.58648 27.2131
337 5HCY 60D 0.000000673 0.4447 27.2131
338 2GU8 796 0.00000008575 0.42527 27.2131
339 3G5D 1N1 0.000000202 0.41212 28.6713
340 4WB6 ATP 0.00000000271 0.62206 28.8525
341 4WB7 ATP 0.0000001033 0.49899 28.8525
342 1VJY 460 0.0000000002242 0.602 29.3729
343 4USF 6UI 0.00001159 0.50197 29.6053
344 4FG8 ATP 0.0000000512 0.62201 29.8361
345 4E93 GUI 0.00000007315 0.524 29.8361
346 4YZN 4K5 0.00000001307 0.63158 29.9652
347 5UOX 8GY 0.00000002307 0.62897 30.2583
348 3H9R TAK 0.00000004176 0.69157 30.4918
349 4DC2 ADE 0.0000002583 0.4553 32.1429
350 4EWH T77 0.00000007104 0.56005 33.0909
351 3PLS ANP 0.0000002482 0.61566 34.2282
352 3KMW ATP 0.000001333 0.58236 34.6863
353 4KS7 X4Z 0.000000562 0.56445 35.274
354 3KRL KRL 0.000008462 0.52146 36.7213
355 3NW7 LGV 0.000008797 0.54979 37.0492
356 4U0I 0LI 0.00007185 0.43054 37.0492
357 3SXS PP2 0.0000001831 0.59834 39.5522
358 1OPK P16 0.00004771 0.43928 40.3279
359 4CSV STI 0.00005242 0.4835 41.8182
360 4TWP AXI 0.000001231 0.4258 43.1734
361 4XLI 1N1 0.0000007132 0.59475 44.0299
362 5LI1 ANP 0.0000000003397 0.70577 45
Pocket No.: 2; Query (leader) PDB : 5GZ9; Ligand: MAN; Similar sites found: 14
This union binding pocket(no: 2) in the query (biounit: 5gz9.bio1) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4GKY MAN 0.003736 0.40599 1.14943
2 3GDN HBX 0.0396 0.40189 1.96721
3 3GDN FAD 0.03211 0.40189 1.96721
4 3MJY IJZ 0.02676 0.40673 2.29508
5 3MJY FMN 0.02676 0.40673 2.29508
6 3S7D SAH 0.03168 0.40557 2.29508
7 3ZW2 NAG GAL FUC 0.00864 0.40324 2.29885
8 3M54 SAH 0.02819 0.41373 3.44828
9 5UAO FAD 0.009506 0.42038 3.60656
10 3FMI KAP 0.0192 0.41882 5.17928
11 1LDN FBP 0.01418 0.4166 5.57377
12 2FAV APR 0.0008415 0.48558 8.33333
13 3AB3 GDP 0.02722 0.41023 9.7561
14 1EBF NAD 0.01049 0.40883 10.1639
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