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Receptor
PDB id Resolution Class Description Source Keywords
5GLT 2 Å NON-ENZYME: BINDING TL-GAL WITH LNT TOXASCARIS LEONINA CRYSTAL STRUCTURES CARBOHYDRATES TL-GALECTIN ANTI-INFLAMMSUGAR BINDING PROTEIN
Ref.: STRUCTURAL BASIS FOR CARBOHYDRATE RECOGNITION AND ANTI-INFLAMMATORY MODULATION BY GASTROINTESTINAL NE PARASITE TOXASCARIS LEONINA GALECTIN J. BIOL. CHEM. V. 291 25326 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC GAL NAG GAL A:301;
B:305;
B:301;
Valid;
Valid;
Valid;
none;
none;
none;
Kd = 24 uM
707.632 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5GLT 2 Å NON-ENZYME: BINDING TL-GAL WITH LNT TOXASCARIS LEONINA CRYSTAL STRUCTURES CARBOHYDRATES TL-GALECTIN ANTI-INFLAMMSUGAR BINDING PROTEIN
Ref.: STRUCTURAL BASIS FOR CARBOHYDRATE RECOGNITION AND ANTI-INFLAMMATORY MODULATION BY GASTROINTESTINAL NE PARASITE TOXASCARIS LEONINA GALECTIN J. BIOL. CHEM. V. 291 25326 2016
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 5GLU Kd = 96 uM SIA GAL GLC n/a n/a
2 5GLT Kd = 24 uM BGC GAL NAG GAL n/a n/a
3 5GM0 Kd = 111 uM GAL BGC n/a n/a
4 5GLZ Kd = 78 uM BGC C6 H12 O6 C([C@@H]1[....
5 5GLW Kd = 54 uM GAL NAG n/a n/a
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 5GLU Kd = 96 uM SIA GAL GLC n/a n/a
2 5GLT Kd = 24 uM BGC GAL NAG GAL n/a n/a
3 5GM0 Kd = 111 uM GAL BGC n/a n/a
4 5GLZ Kd = 78 uM BGC C6 H12 O6 C([C@@H]1[....
5 5GLW Kd = 54 uM GAL NAG n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 5GLU Kd = 96 uM SIA GAL GLC n/a n/a
2 5GLT Kd = 24 uM BGC GAL NAG GAL n/a n/a
3 5GM0 Kd = 111 uM GAL BGC n/a n/a
4 5GLZ Kd = 78 uM BGC C6 H12 O6 C([C@@H]1[....
5 5GLW Kd = 54 uM GAL NAG n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BGC GAL NAG GAL; Similar ligands found: 272
No: Ligand ECFP6 Tc MDL keys Tc
1 BGC GAL NAG GAL 1 1
2 GAL NAG GAL GLC 1 1
3 GAL NGA GLA BGC GAL 0.942857 1
4 LAT NAG GAL 0.786667 1
5 GLC GAL NAG GAL 0.786667 1
6 NAG GAL BGC 0.780822 1
7 GAL GLC NAG GAL FUC 0.768293 0.978261
8 FUC GAL NAG GAL BGC 0.768293 0.978261
9 GLC NAG GAL GAL FUC 0.768293 0.978261
10 GLA GAL NAG FUC GAL GLC 0.764706 0.978261
11 NGA GLA GAL BGC 0.753247 1
12 GLA GAL GAL 0.716418 0.733333
13 A2G GAL NAG FUC GAL GLC 0.684783 0.918367
14 GLC GAL NAG GAL FUC A2G 0.684783 0.918367
15 BGC BGC BGC BGC BGC BGC BGC BGC 0.676056 0.733333
16 GLA GAL NAG 0.666667 1
17 MAN BMA NAG 0.666667 1
18 BGC GAL NAG GAL FUC FUC 0.655556 0.957447
19 GLC GAL NAG GAL FUC FUC 0.655556 0.957447
20 NAG GAL GAL NAG 0.641975 0.9375
21 NAG GAL GAL NAG GAL 0.641975 0.9375
22 GAL NAG GAL NAG GAL NAG 0.641975 0.918367
23 NGA GAL BGC 0.615385 1
24 CBK 0.606061 0.733333
25 BGC GAL 0.606061 0.733333
26 LBT 0.606061 0.733333
27 N9S 0.606061 0.733333
28 B2G 0.606061 0.733333
29 MAL 0.606061 0.733333
30 BMA GAL 0.606061 0.733333
31 GLA GAL 0.606061 0.733333
32 BGC BMA 0.606061 0.733333
33 LAT 0.606061 0.733333
34 GLA GLA 0.606061 0.733333
35 CBI 0.606061 0.733333
36 GLC GAL 0.606061 0.733333
37 MAB 0.606061 0.733333
38 GAL BGC 0.606061 0.733333
39 NAG GAL NAG 0.604938 0.9375
40 GAL MGC 0.589041 0.957447
41 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.588889 0.9375
42 1GN ACY GAL ACY 1GN BGC GAL BGC 0.588889 0.9375
43 FUC BGC GAL NAG GAL 0.586957 0.978261
44 GAL NAG GAL BGC 0.574713 0.957447
45 GLA GAL GLC 0.571429 0.733333
46 MLR 0.571429 0.733333
47 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.571429 0.733333
48 BGC GLC GLC GLC GLC 0.571429 0.733333
49 BMA MAN BMA 0.571429 0.733333
50 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.571429 0.733333
51 BMA BMA BMA BMA BMA 0.571429 0.733333
52 DXI 0.571429 0.733333
53 GAL GAL GAL 0.571429 0.733333
54 MAN BMA BMA BMA BMA 0.571429 0.733333
55 BGC BGC BGC BGC 0.571429 0.733333
56 MAN BMA BMA 0.571429 0.733333
57 GLC BGC GLC 0.571429 0.733333
58 GLC BGC BGC BGC BGC 0.571429 0.733333
59 CE8 0.571429 0.733333
60 BGC GLC GLC GLC 0.571429 0.733333
61 CT3 0.571429 0.733333
62 MAN BMA BMA BMA BMA BMA 0.571429 0.733333
63 BGC BGC BGC BGC BGC BGC 0.571429 0.733333
64 MTT 0.571429 0.733333
65 BGC BGC GLC 0.571429 0.733333
66 GLC BGC BGC BGC 0.571429 0.733333
67 BGC BGC BGC BGC BGC 0.571429 0.733333
68 MT7 0.571429 0.733333
69 BGC BGC BGC GLC 0.571429 0.733333
70 BGC BGC BGC 0.571429 0.733333
71 GLC BGC BGC BGC BGC BGC 0.571429 0.733333
72 CEX 0.571429 0.733333
73 CE6 0.571429 0.733333
74 BGC GLC GLC GLC GLC GLC GLC 0.571429 0.733333
75 GLC GLC GLC GLC GLC 0.571429 0.733333
76 GLC GAL GAL 0.571429 0.733333
77 CE5 0.571429 0.733333
78 BMA BMA BMA BMA BMA BMA 0.571429 0.733333
79 B4G 0.571429 0.733333
80 GLC BGC BGC 0.571429 0.733333
81 MAN MAN BMA BMA BMA BMA 0.571429 0.733333
82 GLC GLC BGC 0.571429 0.733333
83 BGC GLC GLC 0.571429 0.733333
84 CTR 0.571429 0.733333
85 BMA BMA BMA 0.571429 0.733333
86 GLA GAL BGC 0.571429 0.733333
87 CTT 0.571429 0.733333
88 CEY 0.571429 0.733333
89 GAL NGA 0.567568 1
90 NDG GAL 0.567568 1
91 GAL A2G 0.567568 1
92 A2G GAL 0.567568 1
93 NLC 0.567568 1
94 GAL NDG 0.567568 1
95 GAL NGA A2G 0.5625 0.9375
96 FUC BGC GAL NAG 0.555556 0.978261
97 GAL NGA GAL BGC SIA 0.554545 0.865385
98 BGC GAL SIA NGA GAL 0.554545 0.865385
99 GAL NGA SIA GAL BGC 0.554545 0.865385
100 SIA GAL BGC NGA GAL 0.554545 0.865385
101 A2G GAL BGC FUC 0.543478 0.978261
102 NAG NAG BMA MAN 0.532609 0.865385
103 GAL NAG MAN 0.53012 1
104 GLA NAG GAL FUC 0.52809 0.978261
105 GAL NAG GAL FUC 0.52809 0.978261
106 GLC BGC BGC BGC BGC BGC BGC 0.520548 0.733333
107 BGC BGC BGC GLC BGC BGC 0.520548 0.733333
108 BGC GLA GAL FUC 0.517647 0.755556
109 8VZ 0.506494 0.918367
110 GAL SER A2G 0.505882 0.882353
111 NGA SER GAL 0.505882 0.882353
112 GAL TNR 0.505882 0.882353
113 A2G SER GAL 0.505882 0.882353
114 GAL A2G MBN 0.505747 0.957447
115 NAG BMA MAN MAN MAN MAN 0.505263 1
116 NAG NAG BMA MAN MAN 0.505155 0.9375
117 SIA GAL NAG GAL GLC 0.504348 0.849057
118 BGC GAL NAG SIA GAL 0.504348 0.849057
119 SIA GAL NAG GAL BGC 0.504348 0.849057
120 XYT 0.5 0.6
121 GAL A2G THR 0.494253 0.882353
122 NAG GAL 0.493671 1
123 GAL NAG 0.493671 1
124 BGC GAL SIA SIA GAL NGA 0.491228 0.865385
125 BGC GAL SIA NGA GAL SIA 0.491228 0.865385
126 MAN BMA NAG NAG MAN NAG GAL GAL 0.490196 0.918367
127 NAG MAN MAN MAN NAG GAL NAG GAL 0.490196 0.918367
128 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.49 1
129 GAL BGC NAG GAL 0.488636 1
130 NAG MBG 0.4875 0.957447
131 EAG RAM RAM GLC RAM NAG RAM RAM GLC RAM 0.484848 0.9
132 NAG MAN BMA NDG MAN NAG GAL 0.481132 0.918367
133 NAG NAG BMA MAN MAN NAG GAL NAG 0.476636 0.918367
134 M5G 0.476636 0.9375
135 BMA BMA GLA BMA BMA 0.47619 0.733333
136 LAT FUC 0.47561 0.755556
137 8B7 0.47561 0.755556
138 FUC GAL GLC 0.47561 0.755556
139 GLC GAL FUC 0.47561 0.755556
140 BGC GAL FUC 0.47561 0.755556
141 GAL A2G NPO 0.472527 0.714286
142 NPO A2G GAL 0.472527 0.714286
143 GAL NAG GAL 0.47191 0.957447
144 NAG BMA 0.469136 0.897959
145 BMA BMA BMA BMA 0.469136 0.733333
146 NAG BDP NAG BDP NAG BDP NAG 0.46875 0.9
147 ABD 0.467391 0.977778
148 SLT 0.466019 0.918367
149 GLC GLC GLC BGC 0.464286 0.733333
150 GAL SIA NGA GAL 0.463636 0.865385
151 SIA GAL NGA GAL 0.463636 0.865385
152 MAN MAN MAN GLC 0.463415 0.733333
153 FUC C4W NAG BMA MAN 0.462264 0.865385
154 GAL NDG FUC 0.45977 0.978261
155 FUC NDG GAL 0.45977 0.978261
156 GAL MBG 0.459459 0.73913
157 MDM 0.459459 0.73913
158 M13 0.459459 0.73913
159 SIA SIA GAL NGA GAL 0.458333 0.849057
160 FUC GAL NAG GAL FUC 0.458333 0.957447
161 P3M 0.457831 0.6
162 CG3 A2G GAL 0.457447 0.703125
163 SIA GAL BGC 0.457143 0.9
164 GAL BGC SIA 0.457143 0.9
165 BGC SIA GAL 0.457143 0.9
166 GLA GLC SIA 0.457143 0.9
167 SIA GAL GLC 0.457143 0.9
168 BGC GAL SIA 0.457143 0.9
169 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.454545 0.9375
170 LB2 0.452055 0.733333
171 M3M 0.452055 0.733333
172 MAN GLC 0.452055 0.733333
173 NGR 0.452055 0.733333
174 NAG MAN BMA MAN NAG GAL 0.451923 0.9375
175 NAG NGA 0.451219 0.9375
176 NAG A2G 0.451219 0.9375
177 NAG GDL 0.451219 0.9375
178 CBS CBS 0.451219 0.9375
179 CBS 0.451219 0.9375
180 NDG NAG 0.451219 0.9375
181 NAG A2G GAL 0.450549 0.9375
182 NAG NDG BMA 0.450549 0.865385
183 NAG NAG BMA 0.450549 0.865385
184 GAL FUC 0.447368 0.733333
185 MBG A2G 0.445783 0.957447
186 A2G MBG 0.445783 0.957447
187 NAG MAN BMA 0.443182 1
188 MAG FUC GAL 0.443182 0.9375
189 GLA EGA 0.441558 0.73913
190 DR5 0.44 0.73913
191 MMA MAN 0.44 0.73913
192 4U0 0.439252 0.9
193 NAG FUC 0.439024 0.934783
194 LAT GLA 0.438356 0.733333
195 FUC GAL NAG 0.438202 0.978261
196 NDG GAL FUC 0.438202 0.978261
197 NAG MAN MMA 0.438202 0.957447
198 GAL NAG FUC 0.438202 0.978261
199 FUL GAL NAG 0.438202 0.978261
200 FUC GAL NDG 0.438202 0.978261
201 G6S NAG 0.438202 0.725806
202 DR2 0.438202 0.978261
203 NAG GAL FUC 0.438202 0.978261
204 SIA NAG GAL GAL 0.4375 0.849057
205 6PZ BGC GAL 1GN 1GN ACY GAL GAL ACY BGC 0.436508 0.833333
206 GAL LOG 0.435294 0.803571
207 FUC BGC GAL 0.433735 0.755556
208 DR3 0.433333 0.978261
209 NDG NAG NAG 0.430233 0.918367
210 NAG NAG NAG NAG NDG 0.430233 0.918367
211 NAG NAG NAG NAG NAG 0.430233 0.918367
212 NAG NAG NDG 0.430233 0.918367
213 NAG NAG NAG NAG NAG NAG NAG NAG 0.430233 0.918367
214 NAG NAG NAG NDG 0.430233 0.918367
215 NDG NAG NAG NDG 0.430233 0.918367
216 NAG NAG NAG NAG NAG NAG 0.430233 0.918367
217 CTO 0.430233 0.918367
218 NAG NAG NDG NAG 0.430233 0.918367
219 NDG NAG NAG NAG 0.430233 0.918367
220 NAG BMA NAG MAN MAN NAG NAG 0.429907 0.918367
221 U63 0.428571 0.673469
222 ARE 0.427184 0.836735
223 AAO 0.427184 0.836735
224 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.425532 0.702128
225 BGC BGC BGC XYS GAL 0.425532 0.702128
226 BGC BGC BGC XYS BGC BGC 0.425532 0.702128
227 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.425532 0.702128
228 GLC FUC GAL FUC A2G 0.424242 0.957447
229 BGC FUC GAL FUC A2G 0.424242 0.957447
230 NAG NAG BMA MAN MAN MAN MAN 0.421053 0.865385
231 A2G GAL NAG FUC 0.42 0.918367
232 FUC GAL NAG A2G 0.42 0.918367
233 2M4 0.418919 0.733333
234 GAL BGC SIA NGA 0.418803 0.865385
235 SIA GAL BGC NGA 0.418803 0.865385
236 BGC GAL SIA NGA 0.418803 0.865385
237 GLC ACI GLD GLC 0.418367 0.836735
238 GLC G6D ADH GLC 0.418367 0.836735
239 GLC ACI G6D BGC 0.418367 0.836735
240 GLC G6D ACI GLC 0.418367 0.836735
241 FUC GLA A2G 0.417582 0.978261
242 A2G GAL FUC 0.417582 0.978261
243 NGA GAL FUC 0.417582 0.978261
244 FUC GAL A2G 0.417582 0.978261
245 A2G GLA FUC 0.417582 0.978261
246 GLC ACI G6D GLC 0.415842 0.803922
247 GLC ACI GLD GAL 0.415842 0.803922
248 GLA GAL BGC 5VQ 0.414634 0.708333
249 BMA MAN MAN MAN 0.414634 0.733333
250 FUC NAG GLA GAL 0.414141 0.957447
251 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.412844 0.918367
252 GAL SIA NGA GAL SIA 0.412281 0.865385
253 GAL NGA GAL SIA 0.412281 0.849057
254 NAG NAG FUL BMA MAN MAN NAG GAL 0.411765 0.849057
255 NAG MAN MAN 0.408602 1
256 BQZ 0.408451 0.666667
257 CGC 0.407407 0.733333
258 GLC GLC XYP 0.406977 0.733333
259 GAL BGC BGC XYS 0.406593 0.702128
260 BGC SIA SIA GAL 0.403361 0.849057
261 SIA SIA GLA BGC 0.403361 0.849057
262 NAG BDP 0.402299 0.916667
263 MAN MAN BMA MAN 0.402299 0.733333
264 MAN MAN MAN MAN 0.402299 0.733333
265 FUC NAG GAL 0.402174 0.9
266 GLC GLC G6D ACI GLC GLC GLC 0.401961 0.836735
267 G2F BGC BGC BGC BGC BGC 0.4 0.66
268 MAL EDO 0.4 0.702128
269 GLC GLC AGL HMC GLC 0.4 0.803922
270 GLC GLC ACI G6D GLC GLC 0.4 0.803922
271 GLC GLC DAF BGC 0.4 0.803922
272 ACR GLC GLC GLC 0.4 0.803922
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5GLT; Ligand: BGC GAL NAG GAL; Similar sites found with APoc: 484
This union binding pocket(no: 1) in the query (biounit: 5glt.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3GL0 HXX 1.05634
2 2NX1 PEP 1.1236
3 2NX1 RP5 1.1236
4 4H2W 5GP 1.40845
5 3MF2 AMP 1.40845
6 4H2W AMP 1.40845
7 2Y6O 1N1 1.40845
8 4H2X G5A 1.40845
9 6GWR FEW 1.40845
10 1I7E IBS 1.50943
11 2JEN GLC GLC BGC XYS BGC XYS 1.53257
12 5H5A 6OU 1.66667
13 4HIA FMN 1.70455
14 5VC5 96M 1.76056
15 2XK9 XK9 1.76056
16 2YAK OSV 1.76056
17 2C49 ADN 1.76056
18 1OJJ GLC GAL 1.76056
19 1OJK GLC BGC 1.76056
20 2PYW ADP 1.76056
21 5F2T PLM 1.76056
22 4KYS VIB 1.76056
23 2J3M PRI 1.76056
24 2J3M ATP 1.76056
25 1EYE PMM 1.78571
26 3HY8 FMN 1.91571
27 5DQ8 FLF 2.08333
28 3FW9 SLX 2.11268
29 4QMN DB8 2.11268
30 3RJY GLC 2.11268
31 5ZM4 9FU 2.11268
32 5ZM4 AKG 2.11268
33 4Y8D 49J 2.11268
34 4RD0 GDP 2.11268
35 2ZRU FMN 2.11268
36 4J7Q B7N 2.11268
37 3HDY GDU 2.11268
38 3HDY FAD 2.11268
39 2YNE NHW 2.11268
40 2YNE YNE 2.11268
41 1U6R ADP 2.11268
42 3PP0 03Q 2.11268
43 6BS6 GLC GLC GLC GLC GLC GLC GLC 2.11268
44 1SDW IYT 2.11268
45 1XIM XYL 2.11268
46 4PFC 2QX 2.11268
47 1ZB6 GST 2.11268
48 1ZB6 DIN 2.11268
49 1G42 CP2 2.11268
50 4CQE CQE 2.15827
51 4EWH T77 2.18182
52 5A65 TPP 2.30415
53 3ACL 3F1 2.36486
54 5EOB 5QQ 2.46479
55 3THR C2F 2.46479
56 5DXI TRE 2.46479
57 1ZQ5 NAP 2.46479
58 1ZQ5 E04 2.46479
59 1GQG DCD 2.46479
60 4P8K FAD 2.46479
61 4P8K 38C 2.46479
62 2XVD AS6 2.46479
63 4B1W LAB 2.46479
64 1VJY 460 2.46479
65 4RF7 ARG 2.46479
66 2D3M COA 2.46479
67 3UG4 AHR 2.46479
68 3H22 B53 2.46479
69 5G4J EXT 2.46479
70 6GW4 CHO 2.46479
71 4OMJ 2TX 2.51799
72 3BJK CIT 2.61438
73 1NWW HPN 2.68456
74 4L4J NAG NAG BMA MAN NAG 2.71493
75 4WUJ FMN 2.72109
76 6FE1 V14 2.72374
77 1QIN GIP 2.73224
78 6E08 NAP 2.8169
79 5H9Y BGC BGC BGC BGC 2.8169
80 5XIJ ANP 2.8169
81 3T1A 5MA 2.8169
82 4UWJ 7L5 2.8169
83 4UWJ MYA 2.8169
84 5HCY 60D 2.8169
85 1S4M LUM 2.8169
86 4D1J DGJ 2.8169
87 3OVR 5SP 2.8169
88 3OJI PYV 2.8169
89 4BXF AKG 2.8169
90 6EXF LYS 2.8169
91 5XIJ 873 2.8169
92 2BMB PMM 2.8169
93 4I94 ANP 2.8169
94 5D9G GLU ASN LEU TYR PHE GLN 2.84553
95 1QY1 PRZ 2.87356
96 2IUW AKG 2.94118
97 5FBN 5WF 2.95203
98 3AKK ADP 3.07692
99 3KFF ZBT 3.08642
100 3KFF XBT 3.08642
101 5DRB 5FJ 3.16901
102 4NV7 COA 3.16901
103 3TTI KBI 3.16901
104 4WHZ 3NL 3.16901
105 4IE6 UN9 3.16901
106 4W8B GLC BGC BGC XYS BGC XYS XYS GAL 3.16901
107 4GJ3 0XP 3.16901
108 4RPL 3UC 3.16901
109 4RPL FAD 3.16901
110 4KBA 1QM 3.16901
111 5W4W 9WG 3.16901
112 4FHD EEM 3.16901
113 4FHD 0TT 3.16901
114 2V58 LZJ 3.16901
115 2RDQ AKG 3.16901
116 5FP3 3JI 3.16901
117 8CAT NDP 3.16901
118 3ETH ATP 3.16901
119 5EQY 5RA 3.16901
120 6F6D AKG 3.16901
121 3AXX CBI 3.16901
122 2IPI AKY 3.16901
123 4D06 NAR 3.18021
124 3RGA LSB 3.18021
125 4WW7 AMP 3.20856
126 3H7J PPY 3.29218
127 5HCF BGC 3.32103
128 3TM0 ANP 3.42205
129 3TM0 B31 3.42205
130 1IIU RTL 3.44828
131 4QM9 CYS 3.46821
132 3RE4 TO1 3.48837
133 4QA8 PJZ 3.49345
134 4HWS 1B3 3.52113
135 1ODM ASV 3.52113
136 2WSA MYA 3.52113
137 2WSA 646 3.52113
138 5DEY 59T 3.52113
139 2BNJ XYP XYP AHR FER 3.52113
140 2ZQ0 ACR 3.52113
141 4V24 GYR 3.52113
142 4HWT 1B2 3.52113
143 3JU6 ANP 3.52113
144 4U03 GTP 3.52113
145 5BRT CH9 3.52113
146 4YDQ ANP 3.52113
147 4YDQ HFG 3.52113
148 2RFZ CTR 3.52113
149 5XDT ZI7 3.52113
150 3OV6 MK0 3.52113
151 5IVE 6E8 3.52113
152 3V8S 0HD 3.52113
153 5KD6 6C7 3.52113
154 1EWF PC1 3.52113
155 5UR1 YY9 3.52113
156 4Z87 GDP 3.52113
157 2RG0 CTT 3.52113
158 1M0W ANP 3.52113
159 5HES 032 3.58306
160 4DW4 U5P 3.59281
161 2Z77 HE7 3.59712
162 2A1L PCW 3.7037
163 5AYT L6Y 3.77358
164 4YGF AZM 3.84615
165 5B09 4MX 3.84615
166 5Y72 DST 3.87324
167 4MP8 MLI 3.87324
168 4MP8 NAD 3.87324
169 1VA6 P2S 3.87324
170 1VA6 ADP 3.87324
171 5Z46 GST 3.87324
172 3GD9 GLC BGC BGC BGC 3.87324
173 3ZXR IQ1 3.87324
174 3UH0 TSB 3.87324
175 3B6R ADP 3.87324
176 4GCZ FMN 3.87324
177 3ZXR P3S 3.87324
178 1SMR PIV HIS PRO PHE HIS LPL TYR TYR SER 3.87324
179 3AI0 PNW 3.87324
180 5IH9 6BF 3.87324
181 5I49 2KH 3.87324
182 4GYI ADP 3.87324
183 5WX3 COA 3.87324
184 1Z03 OCH 3.87324
185 5AYI BGC 3.87324
186 5THZ SAH 3.87324
187 3WW2 SF6 3.90625
188 3WW2 LPK 3.90625
189 2HFN FMN 3.92157
190 5OX6 A1Z 3.96825
191 4HN1 TYD 3.9801
192 5I0U DCY 4
193 2JIG PD2 4.01786
194 5ML3 DL3 4.02685
195 1Y7P RIP 4.03587
196 4U0W 16G 4.06504
197 5IXG OTP 4.14201
198 5N2D 8J8 4.16667
199 3PFG SAM 4.18251
200 3PFG TLO 4.18251
201 3BXO UPP 4.1841
202 1X0P FAD 4.1958
203 1GP6 DH2 4.22535
204 1GP6 QUE 4.22535
205 1GP6 SIN 4.22535
206 5C3R AKG 4.22535
207 5C3R HMU 4.22535
208 2XMY CDK 4.22535
209 1DGH NDP 4.22535
210 4QCK ASD 4.22535
211 4NW6 2NS 4.22535
212 4QDF 30Q 4.22535
213 6C1S EFV 4.22535
214 1ST0 GTG 4.22535
215 3VRY B43 4.22535
216 6EZ6 C5Z 4.22535
217 3QSB 743 4.22535
218 5HZX 2GE 4.22535
219 1URX AAL GAL AAL GLA 4.25532
220 3E2M E2M 4.32432
221 2YJ0 420 4.34783
222 4MLO PAM 4.34783
223 3GNE FLC 4.36508
224 3QRC SCR 4.4586
225 1N5S ADL 4.46429
226 1UU6 BGC BGC BGC BGC 4.46429
227 2VQ5 HBA 4.47761
228 2CYE COA 4.51128
229 3E8T UQ8 4.54545
230 2PR5 FMN 4.54545
231 6EHH 2GE 4.54545
232 5J75 6GQ 4.54545
233 5BVE 4VG 4.57746
234 5TUF TDC 4.57746
235 5MGD GLC GAL GAL 4.57746
236 5TUF FAD 4.57746
237 1YKD CMP 4.57746
238 4ZDC CO8 4.57746
239 5X8G S0N 4.57746
240 6BU0 IHP 4.58015
241 4XCB HY0 4.5977
242 5ISY NAD 4.6332
243 3TYZ XHP 4.64286
244 3TYZ PAB 4.64286
245 5TFZ 7BC 4.66667
246 3L8W XAN 4.72973
247 1KOR SIN 4.92958
248 1KOR ARG 4.92958
249 1KOR ANP 4.92958
250 3QXQ CE5 4.92958
251 2OBD 2OB 4.92958
252 6ES0 BW8 4.92958
253 2AXR ABL 4.92958
254 3U6W KIV 4.92958
255 4O1P ANP 4.92958
256 1ECE BGC BGC BGC BGC 4.92958
257 2I4O ATP 4.92958
258 2GJ5 VD3 4.93827
259 5UR6 8KM 4.97238
260 5N0L ILE 5.03145
261 2BYC FMN 5.10949
262 3FW3 ETS 5.26316
263 5YIC 8VO 5.28169
264 3M3R BCD 5.28169
265 5MBC FMN 5.28169
266 2WKQ FMN 5.28169
267 3OGV PTQ 5.28169
268 6G9I CXX 5.28169
269 5H2D ERG 5.28169
270 1FH8 XYP XIF 5.28169
271 5ENQ 5QE 5.32544
272 3STD MQ0 5.45455
273 1NMK SFM 5.45455
274 1MJJ HAL 5.47945
275 3TAY MN0 5.52147
276 3UN3 G16 5.6338
277 4NFN 2KC 5.6338
278 5E2N V14 5.6338
279 1OLM VTQ 5.6338
280 3LVW GSH 5.6338
281 5KR7 6X9 5.6338
282 6FUL E7Z 5.6338
283 1Y2F WAI 5.6338
284 6CLV 6MB 5.6338
285 3SLS 77D 5.6338
286 2YBP 2HG 5.6338
287 1DMY AZM 5.64516
288 3QP6 HL6 5.66038
289 3MPB FRU 5.69106
290 1DZK PRZ 5.73248
291 5HA0 LTD 5.76923
292 4Q0P 0MK 5.76923
293 4CSV STI 5.81818
294 5OCG 9R5 5.82011
295 3PG7 PTY 5.85938
296 6D6L FY4 5.88235
297 1KQW RTL 5.97015
298 4NZN 2OU 5.98592
299 4NZN ANP 5.98592
300 2I74 MAN MAN MAN MAN 5.98592
301 5HQA ACR 5.98592
302 3WDX BGC BGC GLC 5.98592
303 2P7Q GG6 6.01504
304 5GP0 GPP 6.04027
305 4ZSD 7I6 6.09756
306 3E8N ATP 6.15836
307 3E8N VRA 6.15836
308 6GBV FMN 6.16438
309 1LFO OLA 6.25
310 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 6.25
311 2Q8E OGA 6.25
312 6GW1 CHO 6.33803
313 1UNB PN1 6.33803
314 1UNB AKG 6.33803
315 1F52 ADP 6.33803
316 6GVZ CHO 6.33803
317 5W1E PHB 6.33803
318 5YU3 NAD 6.33803
319 5YU3 PRO 6.33803
320 6CC0 EWM 6.33803
321 6AIX A3P 6.33803
322 4J25 OGA 6.55022
323 5SVV FMN 6.56934
324 5NBP BGC BGC BGC 6.61765
325 4QRH 0O2 6.66667
326 4YZC STU 6.69014
327 6MPT C30 6.69014
328 3ZMR GLO BGC BGC XYS BGC XYS XYS 6.69014
329 4AZW ATP 6.69014
330 2FLI DX5 6.69014
331 5A5W GUO 6.71937
332 5H2U 1N1 6.74157
333 3AMN CBK 6.79245
334 3AMN CBI 6.79245
335 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 6.91489
336 4IAW LIZ 6.91489
337 1GT4 UNA 6.91824
338 5NEA 8V8 6.92308
339 4WN5 MVC 6.95652
340 2Z6C FMN 6.97674
341 2RKV ZBA 7.04225
342 4BVA T3 7.04225
343 3W8X FTK 7.04225
344 3W8X FAD 7.04225
345 4L9I 8PR 7.04225
346 5LRT ADP 7.04225
347 1KWK GAL 7.04225
348 6D61 4AA 7.17949
349 4GBD MCF 7.20524
350 4WW8 VD9 7.22433
351 2YIP YIO 7.24638
352 5EPQ OLA 7.31707
353 3E7O 35F 7.39437
354 4ITH RCM 7.39437
355 5W10 CMP 7.39437
356 6GNO XDI 7.40741
357 5KEW 6SB 7.44681
358 6GR0 F8W 7.47126
359 5DKK FMN 7.58621
360 3VQ2 LP4 LP5 MYR DAO 7.63889
361 5TBM 79A 7.69231
362 4J36 1HR 7.74648
363 4JJJ CE6 7.74648
364 5JSP DQY 7.74648
365 1ZNY GDP 7.74648
366 4RGA 3PV 7.74648
367 2FNU PMP UD1 7.74648
368 3A6T 8OG 7.75194
369 4LA7 A1O 7.77202
370 3N0Y APC 7.82123
371 4LED XXR 7.83582
372 5UMY TNN 7.85714
373 5FPX GLY SER SER HIS HIS HIS HIS HIS 7.9646
374 2GC0 PAN 7.97872
375 3FON VAL ASN ASP ILE PHE GLU ALA ILE 8
376 2CM4 RCL 8
377 5IXH OTP 8.07453
378 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 8.08081
379 1LEK GLU GLN TYR LYS PHE TYR SER VAL 8.08081
380 5YBN AKG 8.09859
381 4ZU4 4TG 8.10811
382 2YG2 S1P 8.13953
383 3QP8 HL0 8.15217
384 3E85 BSU 8.22785
385 5VNF VAL THR SER VAL VAL 8.28025
386 3IS2 FAD 8.44156
387 3B1Q NOS 8.4507
388 3B00 16A 8.45588
389 1TT8 PHB 8.53659
390 4J6W CTP 8.53659
391 4TW7 37K 8.59375
392 1MH5 HAL 8.69565
393 2YKL NLD 8.7963
394 2WA4 069 8.80282
395 1XLI GLT 8.80282
396 4MNS 2AX 8.80503
397 5OO5 UUA 8.87097
398 1U0A BGC BGC BGC BGC 8.8785
399 4RYV ZEA 9.03226
400 2IO8 ADP 9.15493
401 2XXP DSL 9.15493
402 1OBD ATP 9.15493
403 2V8W MGO 9.21659
404 4R38 RBF 9.28571
405 4ZSI 4R1 9.35672
406 4ZSI GLP 9.35672
407 3PQB VGP 9.38124
408 5FU3 BGC BGC BGC 9.43396
409 4D5B ACX 9.50704
410 1M15 ADP 9.50704
411 1M15 ARG 9.50704
412 4QXB OGA 9.50704
413 1TOI HCI 9.50704
414 3ZO7 K6H 9.57447
415 1NYW DAU 9.64467
416 4ZU5 THM 9.72222
417 1F5F DHT 9.7561
418 5BU3 4W9 9.78261
419 4BG4 ADP 9.85915
420 5MZI FAD 9.85915
421 5MZI FYK 9.85915
422 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 9.89011
423 3W68 VIV 10.1504
424 3VSV XYP 10.2113
425 5AE9 OKO 10.2113
426 2AG4 OLA 10.3659
427 2AG4 LP3 10.3659
428 1ZM1 BGC BGC BGC 10.3734
429 1WKW GTA 10.4712
430 1BHX ASP PHE GLU GLU ILE 10.4762
431 2AGC DAO 10.4938
432 2TPS TPS 10.5727
433 3MTX PGT 10.596
434 4WUP 3UF 10.7692
435 4H2V AMP 10.9091
436 4WOE ADP 10.9155
437 1J3R 6PG 11.0526
438 5A0R ACE GLU VAL ASN PRO 11.1111
439 3L9R L9Q 11.2245
440 4F7E 0SH 11.2245
441 3ILR SGN IXD 11.2676
442 3ILR IXD 11.2676
443 3ILR SGN 11.2676
444 4K55 H6P 11.2903
445 2QL9 CIT 11.3402
446 3EEB IHP 11.4833
447 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 11.5523
448 3AGC RCC 11.5942
449 2UX9 FMN 11.5942
450 1AJ0 PH2 11.7021
451 1AJ0 SAN 11.7021
452 3T50 FMN 11.7188
453 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 11.9792
454 3VMG 9CA 12.1739
455 4JH6 FCN 12.3188
456 2XIQ MLC 12.3239
457 4CVC PQQ 12.6761
458 1OGZ EQU 12.8
459 4XIZ LPP 12.8571
460 1P0Z FLC 12.9771
461 3SCM LGN 13.3803
462 3RUG DB6 13.3803
463 2XCG XCG 13.7324
464 3FW4 CAQ 14.0449
465 2HRL SIA GAL SIA BGC NGA CEQ 14.1732
466 2E56 MYR 15.2778
467 4P25 FUC GAL NAG FUC 15.493
468 1I3U RR1 15.748
469 2BOS GLA GAL 16.1765
470 5NBW 8SK 16.3551
471 1SQI 869 16.5493
472 2V0U FMN 17.8082
473 5EFW FMN 17.931
474 5DJU FMN 17.931
475 5DJT FMN 17.931
476 5FKP 6UL 18.1818
477 4RLT FSE 18.3544
478 5CKW ANP 19.3662
479 1KGI T4A 20.4724
480 3M3E GAL A2G NPO 21.7391
481 5EZU MYR 34.8315
482 3VV1 GAL FUC 37.5
483 1QKQ MAN 39.4366
484 5H9P TD2 44.3038
Pocket No.: 2; Query (leader) PDB : 5GLT; Ligand: BGC GAL NAG GAL; Similar sites found with APoc: 240
This union binding pocket(no: 2) in the query (biounit: 5glt.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5N2F 8HW None
2 3FSM 2NC None
3 3KA2 2NC None
4 4NJS G08 None
5 5NIU 8YZ None
6 6C8X BVR None
7 1I82 BGC BGC 1.0582
8 2OFV 242 1.08303
9 4BJZ P3A 1.40845
10 4BJZ FAD 1.40845
11 1OUK 084 1.40845
12 4LOO SB4 1.40845
13 5NKB 8ZT 1.76056
14 3MVH WFE 1.76056
15 5YB7 FAD 1.76056
16 5YB7 ORN 1.76056
17 3NWQ 2NC 2.0202
18 4XV1 904 2.11268
19 2R5V HHH 2.11268
20 1QD1 FON 2.11268
21 6BXI ANP 2.11268
22 3QT6 2P0 2.11268
23 3OBK PBG 2.11268
24 5YJS SAL 2.11268
25 1DE6 RNS 2.11268
26 5LUN OGA 2.11268
27 3VKC FPQ 2.11268
28 4POS NAG SIA GAL 2.15827
29 2PFC PLM 2.18579
30 2Z6D FMN 2.30769
31 5EH0 5NW 2.32558
32 1UUO BRF 2.46479
33 1UUO FMN 2.46479
34 1UUO ORO 2.46479
35 5MJA 7O3 2.46479
36 4AG8 AXI 2.46479
37 1EQ2 NAP 2.46479
38 6GIN IR2 2.46479
39 2X6T NAP 2.46479
40 3NW7 LGV 2.46479
41 4QIJ 1HA 2.46479
42 4ASE AV9 2.46479
43 3PUR 2HG 2.46479
44 3VHE 42Q 2.46479
45 6D6W GCU 2.46479
46 1UMZ BGC BGC XYS BGC XYS GAL 2.51799
47 1WPY BTN 2.55319
48 5XEG AKG 2.5974
49 5QIN J2V 2.8169
50 5M1Z 6LW AHR 2.8169
51 1RM0 NAI 2.8169
52 3ZGJ RMN 2.8169
53 5N87 N66 2.8754
54 3PTQ NFG 2.9703
55 4RFM 3P6 3.00752
56 6GG9 FMN 3.08642
57 5ZTN CUR 3.16901
58 4P42 PEE 3.16901
59 1DY4 SNP 3.16901
60 2Q0D ATP 3.16901
61 6FMQ ACE DYW GLU THR GLY GLU LEU 3.16901
62 5FNU L6I 3.16901
63 4OJ8 AKG 3.16901
64 4OJ8 2TQ 3.16901
65 1ERB ETR 3.27869
66 5EW9 5VC 3.32103
67 3P7N FMN 3.48837
68 4OPC FDA 3.52113
69 4OPC PGT 3.52113
70 5KD6 LBU 3.52113
71 3EKK GS2 3.52113
72 4MOB ADP 3.52113
73 4U03 TLL 3.52113
74 5JKG 6LF 3.52113
75 3GC8 B45 3.52113
76 4PAB THG 3.52113
77 1BGQ RDC 3.55556
78 6CDG PRO GLY LEU TRP LYS SER 3.59281
79 3AJH BL3 3.62903
80 4BVM VCA 3.7594
81 6C0T EE4 3.87324
82 5NW7 9C2 3.87324
83 5AMV ADA ADA ADA 3.87324
84 5T8O 76Z 3.87324
85 5O9W AKG 3.87324
86 3A72 AHR AHR 3.87324
87 4B7P 9UN 3.91304
88 2YI0 YI0 3.93013
89 3HQR OGA 4.06504
90 5VCV 1N1 4.22535
91 5J6A P46 4.22535
92 4MZU COA 4.22535
93 4MZU TYD 4.22535
94 1TQP ATP 4.25532
95 4IEN GDP 4.29448
96 3JRS A8S 4.32692
97 2P1O IHP 4.375
98 2P1O NLA 4.375
99 3EEL 53T 4.40529
100 4NG2 OHN 4.42478
101 2HK5 1BM 4.44444
102 5LJB RTL 4.44444
103 5TPV TYD 4.57516
104 4IGH ORO 4.57746
105 4IGH 1EA 4.57746
106 4IGH FMN 4.57746
107 1PN0 FAD 4.57746
108 4USF 6UI 4.57746
109 4ORM ORO 4.57746
110 4ORM FMN 4.57746
111 4ORM 2V6 4.57746
112 1PN0 IPH 4.57746
113 2OJW ADP 4.57746
114 4XCB AKG 4.5977
115 5KJZ PCG 4.66667
116 5VM0 9EG 4.6875
117 4X6F 3XU 4.7619
118 4HK8 XYP XYP XYP XYP XYP XYP 4.7619
119 1EWJ BLM 4.7619
120 4IPH 1FJ 4.87805
121 3HAV ATP 4.92958
122 5JFS 6K0 4.92958
123 1REQ DCA 4.92958
124 5T8U LPA 4.92958
125 1Y57 MPZ 4.92958
126 5KTN 13P 4.92958
127 5DX9 T6P 4.92958
128 2H8H H8H 4.92958
129 4AZI OAN 4.92958
130 4I4Z 2NE 4.92958
131 4W9N TCL 4.92958
132 5USZ SKE 4.92958
133 2EQA AMP 4.92958
134 1NE6 SP1 4.947
135 3T64 DU3 4.97238
136 5U98 1KX 5.05051
137 5ANU 58T 5.06329
138 5EYK 5U5 5.08475
139 1VYF OLA 5.18518
140 3LGS SAH 5.24345
141 3LGS ADE 5.24345
142 5FXD H7Y 5.28169
143 3H4V DVP 5.28169
144 1TYU GLA MAN RAM TYV GLA MAN RAM TYV 5.28169
145 3I3X U22 5.40541
146 2E3N 6CM 5.4902
147 5DYO FLU 5.50459
148 2ZYI STE 5.6338
149 2NZ2 CIR 5.6338
150 4H6B 10Y 5.64103
151 5A67 3PO 5.66038
152 1SU2 ATP 5.66038
153 4RFR RHN 5.91133
154 5AE2 FAD 5.98592
155 5AE2 FYC 5.98592
156 2AMV BIN 5.98592
157 3BMN NAP 5.98592
158 4CM9 NAP 5.98592
159 3JQF NAP 5.98592
160 5G48 1FL 5.98592
161 3DNT ATP 6.33803
162 4I42 1HA 6.33803
163 4MA6 28E 6.36943
164 5AIG VPR 6.4
165 3L5R 47X 6.55738
166 3A7R LAQ 6.69014
167 4PU5 ANP 6.69014
168 3FP0 FP0 6.69014
169 4C2V YJA 6.81818
170 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 7
171 5WL1 CUY 7.04225
172 5WL1 D3D 7.04225
173 5EO8 TFU 7.04225
174 2RKV COA 7.04225
175 2VFT SOR 7.04225
176 1NSZ GLC 7.04225
177 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 7.14286
178 5BV6 35G 7.23684
179 2JEQ GAL BGC BGC BGC XYS BGC XYS 7.39437
180 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 7.39437
181 5JSD 1GN ACY GAL ACY 1GN BGC GAL BGC 7.39437
182 1QCA FUA 7.51174
183 4J36 FAD 7.74648
184 6FXR AKG 7.74648
185 4HSJ 6PC 8.04598
186 5XQW 8EU 8.05687
187 5HMR FDZ 8.09859
188 5XWV 8H6 8.09859
189 2QZT PLM 8.10811
190 2YG2 FLC 8.13953
191 1YRX FMN 8.26446
192 4LIT AKG 8.4507
193 1J3I NDP 8.53659
194 2Y88 2ER 8.60656
195 1C4Q GLA GAL BGC 8.69565
196 3D72 FAD 8.72483
197 4OFG PCG 9.02778
198 3MWS 017 9.09091
199 3PNA CMP 9.09091
200 5X1M DHB 9.15493
201 5X1M THG 9.15493
202 2J9C ATP 9.2437
203 2J9D ADP 9.2437
204 3PVW QRX 9.45946
205 4WO4 JLS 9.48905
206 2IRY DGT 9.50704
207 4G31 0WH 9.85915
208 4B7H NDP 9.85915
209 4OCT AKG 9.90991
210 5C9J STE 9.96441
211 3OZ2 OZ2 10.2113
212 1R5L VIV 10.3053
213 6EUW BYB 10.4294
214 4RDL FUC GAL NDG FUC 10.5634
215 1NOW IFG 10.5634
216 1OGX EQU 10.687
217 5FD0 NAG 10.9155
218 6FA4 D1W 10.9827
219 3L9R L9R 11.2245
220 4L3L 5FI 11.6197
221 2CIG 1DG 11.9497
222 1N07 FMN 12.2699
223 1EM6 CP4 13.0282
224 3O2K DST 13.0282
225 4EES FMN 13.0435
226 3JQ3 ADP 13.1148
227 3CBC DBS 13.1313
228 3G08 FEE 13.3803
229 3QUZ QUV 13.3803
230 5DEP UD1 14.3411
231 6ER4 SIA GAL BGC 14.9485
232 1OPB RET 15.6716
233 2BOS GLA GAL GLC 16.1765
234 5JAX 6J7 18.5185
235 4M1U MBG A2G 18.5714
236 4M1U A2G MBG 18.5714
237 3TCT 3MI 18.8976
238 1Q79 3AT 20.0704
239 4K3H 1OM 22.8814
240 4B1M FRU FRU 28.1081
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