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Receptor
PDB id Resolution Class Description Source Keywords
5FWA 1.8 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRA WITH CP1 MUS MUSCULUS TRANSFERASE S-ADENOSYL-L-METHIONINE
Ref.: STRUCTURAL STUDIES OF PROTEIN ARGININE METHYLTRANSF REVEAL ITS INTERACTIONS WITH POTENTIAL SUBSTRATES A INHIBITORS. FEBS J. V. 284 77 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:1451;
A:1450;
A:1449;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
CL A:1448;
Invalid;
none;
submit data
35.453 Cl [Cl-]
CA A:1452;
A:1453;
Part of Protein;
Invalid;
none;
none;
submit data
40.078 Ca [Ca+2...
PG4 A:1447;
Invalid;
none;
submit data
194.226 C8 H18 O5 C(COC...
J7C A:1446;
Valid;
none;
ic50 = 16.3 uM
322.323 C12 H18 N8 O3 [H]/N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FWA 1.8 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRA WITH CP1 MUS MUSCULUS TRANSFERASE S-ADENOSYL-L-METHIONINE
Ref.: STRUCTURAL STUDIES OF PROTEIN ARGININE METHYLTRANSF REVEAL ITS INTERACTIONS WITH POTENTIAL SUBSTRATES A INHIBITORS. FEBS J. V. 284 77 2017
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5FUL ic50 = 18.3 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5FWA ic50 = 16.3 uM J7C C12 H18 N8 O3 [H]/N=C(N)....
3 5FWD - GJV C13 H21 N8 O3 c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5FUL ic50 = 18.3 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5FWA ic50 = 16.3 uM J7C C12 H18 N8 O3 [H]/N=C(N)....
3 5FWD - GJV C13 H21 N8 O3 c1nc(c2c(n....
50% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5FUL ic50 = 18.3 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5FWA ic50 = 16.3 uM J7C C12 H18 N8 O3 [H]/N=C(N)....
3 5FWD - GJV C13 H21 N8 O3 c1nc(c2c(n....
4 4Y30 ic50 = 10 nM 49L C25 H38 N4 O3 CNCCN(C)Cc....
5 4Y2H ic50 = 0.011 uM 49K C13 H17 F N4 CN(CCN)Cc1....
6 5EGS ic50 = 0.3 uM 5NR C14 H22 N2 c1ccc(cc1)....
7 4RYL ic50 = 31 nM 3ZG C16 H18 N4 O2 c1cc2cnccc....
8 5FUB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 5G02 - SFG C15 H23 N7 O5 c1nc(c2c(n....
10 2Y1W - SFG C15 H23 N7 O5 c1nc(c2c(n....
11 5DXJ - SFG C15 H23 N7 O5 c1nc(c2c(n....
12 3B3F - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: J7C; Similar ligands found: 246
No: Ligand ECFP6 Tc MDL keys Tc
1 J7C 1 1
2 6RE 0.820895 0.985507
3 GJV 0.689189 0.971429
4 RAB 0.651515 0.842857
5 ADN 0.651515 0.842857
6 XYA 0.651515 0.842857
7 5N5 0.632353 0.869565
8 5CD 0.623188 0.828571
9 A4D 0.623188 0.842857
10 EP4 0.619718 0.797297
11 DTA 0.611111 0.783784
12 3DH 0.608108 0.794521
13 MTA 0.60274 0.794521
14 M2T 0.589041 0.753247
15 AMP 0.571429 0.789474
16 A 0.571429 0.789474
17 A3N 0.56962 0.833333
18 SRA 0.564103 0.75
19 DSH 0.556962 0.863014
20 MHZ 0.554217 0.777778
21 AU1 0.554217 0.75
22 LMS 0.551282 0.678161
23 ZAS 0.551282 0.835616
24 A2D 0.55 0.746835
25 ABM 0.55 0.746835
26 AOC 0.5375 0.794521
27 A3G 0.5375 0.873239
28 MAO 0.536585 0.756098
29 AP2 0.536585 0.7625
30 BA3 0.536585 0.746835
31 A12 0.536585 0.7625
32 CA0 0.535714 0.728395
33 ADX 0.535714 0.678161
34 B4P 0.53012 0.746835
35 5AS 0.53012 0.677778
36 AP5 0.53012 0.746835
37 ADP 0.53012 0.769231
38 SFG 0.529412 0.84507
39 5X8 0.529412 0.833333
40 5AD 0.528571 0.768116
41 S4M 0.52439 0.7875
42 AT4 0.52381 0.740741
43 AN2 0.52381 0.759494
44 SON 0.52381 0.7625
45 A7D 0.52381 0.847222
46 PRX 0.523256 0.75
47 ANP 0.522727 0.75
48 NEC 0.518519 0.791667
49 M33 0.517647 0.7375
50 SA8 0.517241 0.815789
51 0UM 0.516129 0.828947
52 ACP 0.511628 0.772152
53 ATP 0.511628 0.769231
54 A3T 0.511628 0.819444
55 HEJ 0.511628 0.769231
56 50T 0.511628 0.759494
57 SAH 0.511364 0.835616
58 G5A 0.511364 0.715909
59 IOT 0.509434 0.829268
60 A3S 0.505882 0.859155
61 APC 0.505747 0.7625
62 AR6 0.505747 0.746835
63 APR 0.505747 0.746835
64 AQP 0.505747 0.769231
65 5FA 0.505747 0.769231
66 GAP 0.505618 0.772152
67 SAP 0.5 0.731707
68 7D7 0.5 0.763889
69 Y3J 0.5 0.746479
70 ADP PO3 0.5 0.766234
71 AAT 0.5 0.84
72 5AL 0.5 0.7375
73 ADV 0.5 0.740741
74 AGS 0.5 0.731707
75 AD9 0.5 0.75
76 A5D 0.5 0.783784
77 RBY 0.5 0.740741
78 JB6 0.494845 0.743902
79 NVA LMS 0.494737 0.673913
80 AHX 0.494737 0.756098
81 MAP 0.494624 0.731707
82 ATF 0.494505 0.740741
83 A5A 0.494505 0.662921
84 SAI 0.494382 0.824324
85 9ZA 0.489362 0.722892
86 9ZD 0.489362 0.722892
87 S7M 0.48913 0.772152
88 SMM 0.48913 0.743902
89 SRP 0.48913 0.78481
90 SSA 0.48913 0.696629
91 TAT 0.488889 0.740741
92 T99 0.488889 0.740741
93 SAM 0.488889 0.772152
94 ACQ 0.488889 0.772152
95 4AD 0.484211 0.753086
96 52H 0.483871 0.641304
97 VMS 0.483871 0.648352
98 54H 0.483871 0.648352
99 EEM 0.483516 0.772152
100 QQX 0.481481 0.691358
101 3AM 0.481481 0.776316
102 DLL 0.479167 0.7375
103 TSB 0.478723 0.655556
104 5CA 0.478723 0.696629
105 DAL AMP 0.478723 0.7375
106 8X1 0.478723 0.711111
107 53H 0.478723 0.641304
108 ADP ALF 0.478261 0.710843
109 ALF ADP 0.478261 0.710843
110 SO8 0.477778 0.786667
111 2VA 0.477273 0.797297
112 YLB 0.476636 0.752941
113 YLP 0.47619 0.752941
114 XAH 0.475248 0.771084
115 3UK 0.474227 0.728395
116 K15 0.474227 0.78481
117 5SV 0.473684 0.714286
118 3AD 0.473684 0.855072
119 8QN 0.473684 0.7375
120 OOB 0.473684 0.7375
121 S8M 0.473684 0.802632
122 ADP VO4 0.473118 0.7375
123 VO4 ADP 0.473118 0.7375
124 6YZ 0.473118 0.772152
125 KAA 0.469388 0.711111
126 B5V 0.469388 0.719512
127 LAD 0.469388 0.790123
128 NSS 0.46875 0.677778
129 LSS 0.46875 0.663043
130 DSZ 0.46875 0.677778
131 PAJ 0.46875 0.705882
132 AMO 0.46875 0.7625
133 NVA 2AD 0.466667 0.826667
134 A3P 0.465116 0.766234
135 NB8 0.464646 0.73494
136 3OD 0.464646 0.728395
137 TXA 0.464646 0.719512
138 1ZZ 0.464646 0.689655
139 SXZ 0.464646 0.772152
140 62X 0.463918 0.765432
141 00A 0.463918 0.702381
142 A22 0.463158 0.759494
143 YLC 0.462963 0.771084
144 VRT 0.461538 0.837838
145 ARG AMP 0.461538 0.85
146 KB1 0.46 0.805195
147 MYR AMP 0.46 0.689655
148 AYB 0.459459 0.744186
149 OAD 0.459184 0.728395
150 9X8 0.459184 0.710843
151 LEU LMS 0.459184 0.655914
152 GEK 0.458333 0.802632
153 25A 0.458333 0.769231
154 ACK 0.457831 0.736842
155 QQY 0.457831 0.7
156 KH3 0.457143 0.797468
157 7D5 0.45679 0.734177
158 9SN 0.455446 0.694118
159 WAQ 0.454545 0.743902
160 PR8 0.454545 0.780488
161 GSU 0.454545 0.696629
162 P5A 0.454545 0.703297
163 ADQ 0.453608 0.75
164 A1R 0.453608 0.7875
165 A3R 0.453608 0.7875
166 OVE 0.452381 0.7375
167 2AM 0.451219 0.766234
168 B5Y 0.45098 0.710843
169 YLA 0.45045 0.752941
170 PTJ 0.45 0.714286
171 ME8 0.45 0.729412
172 BIS 0.45 0.743902
173 FYA 0.45 0.782051
174 D3Y 0.447917 0.835616
175 YSA 0.446602 0.677778
176 ADP BMA 0.444444 0.75
177 A6D 0.444444 0.719512
178 F2R 0.442478 0.839506
179 4UV 0.442308 0.710843
180 AMP DBH 0.442308 0.728395
181 RP1 0.440476 0.703704
182 SP1 0.440476 0.703704
183 A A 0.44 0.769231
184 CC5 0.44 0.84058
185 2A5 0.43956 0.772152
186 FA5 0.436893 0.7625
187 B5M 0.436893 0.710843
188 8PZ 0.436893 0.677778
189 YAP 0.436893 0.753086
190 PPS 0.43617 0.678161
191 9K8 0.435644 0.621053
192 PAP 0.434783 0.75641
193 7MD 0.433962 0.771084
194 4UU 0.433962 0.710843
195 YLY 0.432203 0.744186
196 CMP 0.431818 0.75
197 2BA 0.431818 0.74026
198 A2P 0.431818 0.753247
199 25L 0.431373 0.759494
200 NAI 0.431193 0.702381
201 4YB 0.429907 0.681319
202 TYR AMP 0.428571 0.753086
203 LAQ 0.425926 0.689655
204 3NZ 0.425743 0.802632
205 ATP A A A 0.423077 0.75641
206 LPA AMP 0.422018 0.689655
207 GA7 0.420561 0.7625
208 AFH 0.420561 0.72619
209 7D3 0.420455 0.716049
210 NAX 0.418182 0.738095
211 4UW 0.418182 0.686047
212 3D1 0.417722 0.819444
213 3L1 0.417722 0.819444
214 MTP 0.417722 0.727273
215 ARX 0.417391 0.918919
216 TAD 0.416667 0.705882
217 DQV 0.416667 0.7375
218 WSA 0.414414 0.685393
219 OMR 0.414414 0.681818
220 COD 0.413793 0.727273
221 AHZ 0.412844 0.689655
222 2FA 0.4125 0.810811
223 26A 0.4125 0.76
224 6MD 0.4125 0.805556
225 7C5 0.411215 0.84
226 G3A 0.411215 0.777778
227 7MC 0.410714 0.752941
228 V3L 0.410526 0.769231
229 N0B 0.409836 0.752941
230 48N 0.409091 0.756098
231 AR6 AR6 0.407407 0.746835
232 5F1 0.407407 0.777778
233 G5P 0.407407 0.777778
234 6V0 0.405405 0.714286
235 TXD 0.405405 0.722892
236 DND 0.405405 0.719512
237 NXX 0.405405 0.719512
238 ATR 0.404255 0.74359
239 GGZ 0.40404 0.636364
240 GTA 0.40367 0.75
241 7D4 0.402174 0.716049
242 A A A 0.401961 0.759494
243 649 0.401786 0.666667
244 AF3 ADP 3PG 0.401786 0.705882
245 TXE 0.401786 0.722892
246 TYM 0.401786 0.7625
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FWA; Ligand: J7C; Similar sites found with APoc: 512
This union binding pocket(no: 1) in the query (biounit: 5fwa.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 1KYA XYD 1.12108
3 1YQZ FAD 1.14155
4 1ELI PYC 1.28535
5 1PJS NAD 1.34529
6 3ICT ADP 1.34529
7 3ICS ADP 1.34529
8 1H82 FAD 1.34529
9 1H82 GZZ 1.34529
10 4MOP 2H5 1.34529
11 3ICR FAD 1.34529
12 5E72 SAM 1.44509
13 1J1R ADE 1.53257
14 5X7Q GLC GLC GLC GLC 1.56951
15 3AXB FAD 1.56951
16 3AXB PRO 1.56951
17 1RSG FAD 1.56951
18 1D4D FAD 1.56951
19 3NKS FAD 1.56951
20 2GV8 FAD 1.56951
21 2GVC FAD 1.56951
22 3K7M FAD 1.62413
23 5G3U ITW 1.65485
24 5G3U FDA 1.65485
25 4YAC NAI 1.6835
26 4RD0 GDP 1.68675
27 3O7W SAM 1.70068
28 5HJM MTA 1.70455
29 3LST SAH 1.72414
30 4IWN GEK 1.74672
31 5N5D SAM 1.76991
32 3LCV SAM 1.77936
33 4D04 FAD 1.79372
34 4D04 NAP 1.79372
35 4MIG G3F 1.79372
36 5TS5 FAD 1.79372
37 2Q28 ADP 1.79372
38 1YY5 FAD 1.79372
39 2XVF FAD 1.79372
40 1UWK NAD 1.79372
41 1UWK URO 1.79372
42 2PXX SAH 1.86047
43 4EUE NAI 1.91388
44 5MPT SAH 1.93237
45 5YF1 8V0 1.9337
46 5YF1 SFG 1.9337
47 2UYQ SAM 1.93548
48 2WPB ZZI 1.97368
49 6FBA D48 2.00573
50 2JBM SRT 2.00669
51 6F97 FAD 2.01794
52 4HA6 FAD 2.01794
53 5OC1 FAD 2.01794
54 1NAA 6FA 2.01794
55 1NAA ABL 2.01794
56 4UHL VFV 2.01794
57 1QO8 FAD 2.01794
58 3H8V ATP 2.05479
59 1UAY ADN 2.06612
60 1RP0 AHZ 2.11268
61 3TLJ SAH 2.14477
62 1FP1 SAH 2.15054
63 4PIO SAH 2.16718
64 4PIO AVI 2.16718
65 5J60 FAD 2.1875
66 2A8Y MTA 2.22222
67 5WP4 SAH 2.24215
68 4YNU FAD 2.24215
69 4YNU LGC 2.24215
70 6H3O FAD 2.24215
71 3SQP FAD 2.24215
72 4AZW SAM 2.24215
73 1LVL NAD 2.24215
74 5J5Z FAD 2.24215
75 1LVL FAD 2.24215
76 1G60 SAM 2.30769
77 4KRI SAH 2.30947
78 3MYU VIB 2.32558
79 4XFR CIT 2.34192
80 6C5B SAH 2.34604
81 1RYI GOA 2.35602
82 1RYI FAD 2.35602
83 2Q1W NAD 2.4024
84 4MO2 FAD 2.44565
85 4MO2 FDA 2.44565
86 5WP5 SAH 2.46637
87 2IVD FAD 2.46637
88 2BRY FAD 2.46637
89 4LHD GLY 2.46637
90 1GET FAD 2.46637
91 1GET NAP 2.46637
92 4TXI FAD 2.46637
93 1BZL GCG 2.46637
94 4B63 ORN 2.46637
95 4B63 NAP 2.46637
96 4B63 FAD 2.46637
97 2JHP SAH 2.46637
98 2VVL FAD 2.46637
99 5U8U FAD 2.46637
100 5KMS NAD 2.46914
101 6F7L FAD 2.48869
102 3T31 FAD 2.51716
103 3T31 DCQ 2.51716
104 1U2Z SAH 2.54042
105 5MGZ SAH 2.54237
106 5ME4 HP4 2.55474
107 1SQF SAM 2.5641
108 4RVG TYD 2.58216
109 4RVG SAM 2.58216
110 4XNV BUR 2.61283
111 4Y9D NAI 2.62295
112 2FJK 13P 2.62295
113 2O07 SPD 2.63158
114 2O07 MTA 2.63158
115 4NTD FAD 2.64706
116 5JJR SAH 2.69058
117 2YG3 FAD 2.69058
118 2RAB NAD 2.69058
119 2RAB FAD 2.69058
120 3Q9T FAY 2.69058
121 5XNC MTA 2.69542
122 1XTP SAI 2.75591
123 4RDH AMP 2.77778
124 4RDI ATP 2.77778
125 1L1E SAH 2.78746
126 1TPY SAH 2.78746
127 5W7R SAH 2.7972
128 4ONQ SFG 2.80112
129 1NJR XYL 2.8169
130 4A6D SAM 2.83286
131 1DL5 SAH 2.83912
132 5KXE 6Y2 2.88066
133 4UCI SAM 2.89157
134 4D79 ATP 2.89855
135 5E1M PRO PRO LYS ARG ILE ALA 2.90456
136 5E1M SAH 2.90456
137 5TWB FAD 2.90698
138 3PT9 SAH 2.9148
139 4AP3 FAD 2.9148
140 4AP3 NAP 2.9148
141 5O42 9JW 2.91971
142 5O42 NAD 2.91971
143 5O42 BGC 2.91971
144 2EG5 SAH 2.95699
145 4ZCC NAI 2.97619
146 4ZCC FAD 2.97619
147 3VSE SAH 3.01508
148 3CBG SAH 3.01724
149 2BZG SAH 3.01724
150 5K0A FAD 3.0303
151 1Q0S SAH 3.0888
152 3SSO SAH 3.10263
153 5FTW SAH 3.125
154 1V59 NAD 3.13901
155 3QVP FAD 3.13901
156 3GD4 FAD 3.13901
157 3GD4 NAD 3.13901
158 4BV6 FAD 3.13901
159 3UCL FAD 3.13901
160 3UCL CYH 3.13901
161 3UCL NAP 3.13901
162 5UI2 SUC 3.15457
163 3GU3 SAH 3.16901
164 5E9W SAH 3.20513
165 3G89 SAM 3.21285
166 3U1T MLI 3.23625
167 3MAG SAH 3.25733
168 4D7E FAD 3.2634
169 3HDY FDA 3.27456
170 3HDY GDU 3.27456
171 3HDY FAD 3.27456
172 1QAN SAH 3.27869
173 3FXU TSU 3.27869
174 1VQW FAD 3.28228
175 3FUU ADN 3.32103
176 3BXO SAM 3.34728
177 5UFN SAH 3.36134
178 6ER9 FAD 3.36323
179 3AYI HCI 3.36323
180 3AYI FAD 3.36323
181 6ER9 NAP 3.36323
182 3MCT SAH 3.367
183 4TM3 FAD 3.386
184 2PT9 2MH 3.42679
185 2PT9 S4M 3.42679
186 1ZEM NAD 3.43511
187 4N49 SAM 3.50467
188 1WG8 SAM 3.50877
189 4RPL FAD 3.50877
190 4RPL 3UC 3.50877
191 5GWX SAM 3.52113
192 5GWX SAR 3.52113
193 1GY8 NAD 3.52645
194 3K3G MMU 3.52941
195 1I8T FAD 3.54223
196 5K7U SAM 3.55556
197 4Z24 FAD 3.58744
198 2DKH 3HB 3.58744
199 2DKH FAD 3.58744
200 5VN0 FAD 3.58744
201 5KVA SAM 3.59712
202 5BSZ SAH 3.6
203 2P41 SAH 3.60656
204 4FC7 COA 3.61011
205 4FC7 NAP 3.61011
206 4YUW 4JU 3.61842
207 4YUW S4M 3.61842
208 3ELW SAM 3.66667
209 3ELW GP3 3.66667
210 3FPZ AHZ 3.68098
211 2ZIF SAM 3.7037
212 1JQD SAH 3.76712
213 3UOY FAD 3.81166
214 3UOY NAP 3.81166
215 5X68 FAD 3.83632
216 3VC1 SAH 3.84615
217 3VC1 GST 3.84615
218 2I7C AAT 3.88693
219 6FDF SAH 3.89222
220 3I53 SAH 3.91566
221 1T36 ORN 3.9267
222 2WSB NAD 3.93701
223 2PZM UDP 3.93939
224 2PZM NAD 3.93939
225 6C8R EQV 3.95778
226 6C8R SAH 3.95778
227 1VE3 SAM 3.96476
228 4PNE SAH 3.97351
229 1ZBQ NAD 3.97554
230 3P2E SAH 4
231 5NG7 SER 4.01338
232 2IID PHE 4.03587
233 2IID FAD 4.03587
234 1REO FAD 4.03587
235 5LOG SAH 4.03587
236 2WPF FAD 4.03587
237 2WPF WPF 4.03587
238 1GZ6 NAI 4.07523
239 3TKY SAH 4.07609
240 2PX8 SAH 4.08922
241 5ULP KB1 4.10448
242 4JNA FAD 4.11765
243 3GDH SAH 4.14938
244 2A14 SAH 4.18251
245 3C3Y SAH 4.21941
246 3VYW SAM 4.22078
247 2RGO FAD 4.26009
248 4OBW SAM 4.28016
249 1YXM ADE 4.29043
250 3L9W AMP 4.35835
251 4WGF HX2 4.39024
252 1I1N SAH 4.42478
253 5ERG SAM 4.43864
254 2VDV SAM 4.47154
255 4KIB SAH 4.48179
256 1GPE FAD 4.4843
257 3S1S SAH 4.4843
258 3DUW SAH 4.4843
259 3CGD COA 4.4843
260 3CGD NAD 4.4843
261 3CGD FAD 4.4843
262 5CUQ NSC 4.49438
263 2OBF SAH 4.49827
264 2OBF F83 4.49827
265 3LZW NAP 4.51807
266 3LZW FAD 4.51807
267 5ICE 2H4 4.54545
268 5ICE SAH 4.54545
269 5YJF SAH 4.57746
270 5YJF 8WO 4.57746
271 2CI5 HCS 4.57746
272 4J36 1HR 4.57831
273 4J36 FAD 4.57831
274 4DMG SAM 4.58015
275 3ZF8 GDP 4.59016
276 2R4J 13P 4.59082
277 2R4J FAD 4.59082
278 2WK1 SAH 4.60993
279 5IL1 SAM 4.66667
280 5Y02 HBX 4.6729
281 3KLJ FAD 4.67532
282 3LCC SAH 4.68085
283 2RH4 EMO 4.69314
284 5WGR FAD 4.70852
285 4FWE FAD 4.70852
286 4HSU FAD 4.70852
287 3X0V FAD 4.70852
288 4GUT FAD 4.70852
289 4M73 SAH 4.74777
290 4M73 M72 4.74777
291 1UKG MMA 4.7619
292 4BLW AMP 4.84429
293 4BLW SAH 4.84429
294 3EGI ADP 4.85437
295 2HMT NAI 4.86111
296 3B8I OXL 4.87805
297 1GVF PGH 4.8951
298 1XHC FAD 4.90463
299 4NEC SAH 4.92424
300 5DNK SAH 4.93274
301 6D6Y SAH 4.93274
302 1MO9 FAD 4.93274
303 1MO9 KPC 4.93274
304 5THY SAH 4.93827
305 3RKR NAP 4.96183
306 5XLX SAH 4.96454
307 4R6W PC 5.03876
308 4R6W SAH 5.03876
309 2Q1S NAI 5.03979
310 3DXY SAM 5.04587
311 4YRY FAD 5.07246
312 1KYQ NAD 5.10949
313 1FP2 SAH 5.11364
314 1FP2 HMO 5.11364
315 5N0J FAD 5.12821
316 1COY FAD 5.15695
317 1COY AND 5.15695
318 6GAR FAD 5.15759
319 4RSL FAD 5.16854
320 5JGL SAM 5.19031
321 2GN4 UD1 5.23256
322 2GN4 NDP 5.23256
323 5BW4 SAM 5.24345
324 2PK3 A2R 5.29595
325 3GCZ SAM 5.31915
326 5MLJ 9ST 5.35714
327 5HSA FAS 5.38117
328 3WV8 ATP 5.50459
329 1KPG SAH 5.57491
330 3LKZ SFG 5.60748
331 6BQ6 TER 5.74018
332 3BGD PM6 5.76923
333 3BGD SAH 5.76923
334 1Y8Q ATP 5.8296
335 2XVE FAD 5.8296
336 5FJN FAD 5.8296
337 5FJN BE2 5.8296
338 3AB1 FAD 5.83333
339 3A4T SFG 5.83942
340 4DCM SAM 5.86667
341 1XDS SAM 5.88235
342 4LH7 1X8 5.88235
343 3ITJ CIT 5.91716
344 3ITJ FAD 5.91716
345 1KPH SAH 5.92335
346 3G2O SAM 6.02007
347 4XQC 13D 6.05381
348 2Z3Y F2N 6.05381
349 4XQC NAD 6.05381
350 1G55 SAH 6.12245
351 1QZZ SAM 6.14973
352 2Q7V FAD 6.15385
353 5YEC ATP 6.17647
354 6DUB SAH 6.30631
355 3P9C SAH 6.31868
356 5YJI SAH 6.33803
357 5YJI 8WO 6.33803
358 6GAS FAD 6.34441
359 5M58 SAH 6.52174
360 2ZE3 AKG 6.54545
361 2XYQ SAH 6.55738
362 3ZNN 4WL 6.62824
363 3ZNN FAD 6.62824
364 5EXK 5AD 6.64653
365 4QTU SAM 6.66667
366 5JCM ISD 6.72646
367 5JCM FAD 6.72646
368 5JCM NAD 6.72646
369 1WY7 SAH 6.76329
370 3GWZ SAH 6.77507
371 3GXO SAH 6.77507
372 6B92 SAH 6.80272
373 2JJQ SAH 6.82353
374 3PFG SAM 6.84411
375 3PFG TLO 6.84411
376 1RJD SAM 6.88623
377 5THZ SAH 6.91358
378 4X7Y SAH 6.93431
379 3OFK SAH 6.94444
380 2WR1 NAG 6.95067
381 1ZOS MTM 6.95652
382 1ZGA SAH 7.0028
383 2EFJ SAH 7.03125
384 5U19 827 7.03812
385 5U19 SAH 7.03812
386 2NXE SAM 7.08661
387 1JQ3 AAT 7.09459
388 3GRU AMP 7.11864
389 2CDU ADP 7.17489
390 2FK8 SAM 7.17489
391 2CDU FAD 7.17489
392 3NDJ JHZ 7.21154
393 3NDJ SAH 7.21154
394 3NUG NAD 7.28745
395 5TPC GAL SIA NGA GAL SIA 7.29412
396 3JWH SAH 7.37327
397 3H2B SAH 7.38916
398 3M6W SAM 7.3991
399 1P1C SAH 7.53769
400 5EB3 UEG 7.54717
401 5KOK SAH 7.55667
402 5KOK S9T 7.55667
403 5KOK R9T 7.55667
404 3DMH GMP 7.61155
405 3DMH SAM 7.61155
406 2HQM FAD 7.62332
407 2EJU SAH 7.67196
408 1Z3C SA8 7.71812
409 4USQ FAD 7.75623
410 3OU2 SAH 7.79817
411 4AVV GHE 7.84314
412 4AVV CD 7.84314
413 3EVG SAH 7.84753
414 4REP FAD 7.84753
415 2AOT SAH 7.87671
416 3KO0 TFP 7.92079
417 3QXV MTX 7.93651
418 6GFK SAH 7.96813
419 2ZWA SAH 8.07175
420 1NW5 SAM 8.15047
421 1I9G SAM 8.21429
422 5I7A 68Q 8.28221
423 1N2X SAM 8.30565
424 2ZFU SAH 8.37209
425 3FZG SAM 8.5
426 3GEG NAD 8.50202
427 5EEH P9P 8.51064
428 5EEH SAH 8.51064
429 5X62 SAH 8.62069
430 2WA2 SAM 8.69565
431 2HNK SAH 8.78661
432 2DPM SAM 8.80282
433 3QOX SAH 8.92019
434 5W7K SAH 8.97436
435 5BJX UDP 9.19283
436 5BJX NAD 9.19283
437 1LSS NAD 9.28571
438 4ZRN UPG 9.29487
439 4ZRN NAD 9.29487
440 5ZW3 SAH 9.33333
441 1NV8 SAM 9.50704
442 1NV8 MEQ 9.50704
443 3MQ2 SAH 9.63303
444 6ECT SAM 9.65732
445 1ODJ GMP 9.78723
446 3FRH SAH 9.88142
447 4PTN GXV 9.91254
448 3A27 SAM 9.92647
449 5F8F SFG 10.0796
450 3LAD FAD 10.0897
451 1R18 SAH 10.1322
452 5MW4 5JU 10.1796
453 1XCL SAH 10.2128
454 43CA NPO 10.2564
455 2GAG NAD 10.3704
456 3Q87 SAM 10.4
457 1JG3 ADN 10.6383
458 3TKA SAM 10.6628
459 3T7S SAM 10.8209
460 4KRG SAH 10.9865
461 5GM1 SAH 11.1111
462 5FA8 SAM 11.1801
463 5DLY 5D7 11.2782
464 5DLY SAH 11.2782
465 3AD8 NAD 11.33
466 4POO SAM 11.5
467 5W7M SAH 11.5385
468 5F7J ADE 11.875
469 1IM8 SAI 11.8852
470 2YX1 SFG 12.2024
471 5L95 AMP 12.5
472 1ZQ9 SAM 12.6316
473 3EVF GTA 12.6354
474 3EVF SAH 12.6354
475 6ECU SAH 12.6582
476 6ECW SAH 12.6984
477 5DM1 5D7 12.7341
478 5DM1 SAH 12.7341
479 5JE0 SAH 12.9555
480 5JE0 AZ8 12.9555
481 4II2 ATP 13.253
482 3FPF TNA 13.4228
483 3FPF MTA 13.4228
484 4YMH SAH 14.1667
485 2XVM SAH 14.5729
486 2PWY SAH 14.7287
487 6F5Z SAH 14.7541
488 6GKV SAH 15.0997
489 1KYZ SAH 15.3425
490 3C6K MTA 15.4856
491 3C6K SPD 15.4856
492 3MB5 SAM 15.6863
493 5T67 JHZ 16.5865
494 5T67 SAH 16.5865
495 4CQM NAP 16.8033
496 3X0D SAH 17.0404
497 1GTE FAD 18.6099
498 3A25 SAM 19.6013
499 5E8J SAH 22.7273
500 4XUC 43G 23.8532
501 4XUC SAM 23.8532
502 1EJ0 SAM 23.8889
503 4X60 3XV 23.991
504 4X60 SFG 23.991
505 4FZV SAM 25.0696
506 4C4A SAH 27.5785
507 3HVJ 705 30.3167
508 4M37 SAH 36.7347
509 4M38 SAH 36.7347
510 1L3I SAH 36.9792
511 4LWP SAH 42.3913
512 5DXA SFG 46.1318
Pocket No.: 2; Query (leader) PDB : 5FWA; Ligand: J7C; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5fwa.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
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