Receptor
PDB id Resolution Class Description Source Keywords
5FK8 1.88 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEO-ERLOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE AMINO ACID SEQUENCE CARBOHYDRATES CATALYSIS CADOMAIN CLONING DIMERIZATION QUATERNARY PICHIA PASTORISGLYCOSIDE HYDROLASES FUNGAL PROTEINS KINETICS MOLECULARMOLECULAR CONFORMATION PROTEIN CONFORMATION PROTEIN STRUCSECONDARY SUBSTRATE SPECIFICITY BETA-FRUCTOFURANOSIDASE INVERTASE PREBIOTICS NEOERLOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG NAG BMA MAN MAN MAN H:1;
 Invalid;
 none;
 submit data
n/a n/a
NAG A:1644;
A:1555;
B:1471;
B:1644;
A:1125;
B:1215;
A:1512;
B:1052;
A:1319;
B:1555;
B:1319;
A:1483;
B:1483;
A:1606;
B:1242;
A:1471;
A:1236;
B:1125;
A:1215;
B:1357;
A:1357;
B:1539;
A:1539;
A:1052;
B:1444;
A:1242;
A:1444;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN I:1;
I:1;
 Invalid;
Invalid;
 none;
none;
 submit data
1721.53 n/a O=C(N...
GLC GLC FRU G:1;
C:1;
 Valid;
Valid;
 none;
none;
 submit data
504.438 n/a O(CC1...
NAG NAG F:1;
J:1;
 Invalid;
Invalid;
 none;
none;
 submit data
408.404 n/a O=C(N...
NAG NAG BMA MAN MAN MAN MAN D:1;
 Invalid;
 none;
 submit data
1219.11 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FMD 1.78 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE CARBOHYDRATES CATALYSIS CATALYTIC DOMAIN CLONIDIMERIZATION QUATERNARY PICHIA PASTORIS GLYCOSIDE HYDROLFUNGAL PROTEINS KINETICS MOLECULAR CONFORMATION SUBSTRATSPECIFICITY INVERTASE PREBIOTICS NYSTOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - GLC FRU n/a n/a
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - GLC FRU FRU FRU n/a n/a
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - GLC FRU n/a n/a
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - GLC FRU FRU FRU n/a n/a
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - GLC FRU n/a n/a
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - GLC FRU FRU FRU n/a n/a
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GLC GLC FRU; Similar ligands found: 46
No: Ligand ECFP6 Tc MDL keys Tc
1 GLC GLC FRU 1 1
2 GLC FRU FRU 0.597222 0.973684
3 BGC GLC GLC 0.554054 0.868421
4 MAN BMA BMA BMA BMA BMA BMA 0.536232 0.868421
5 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.536232 0.868421
6 GLC GLC GLC GLC BGC GLC GLC 0.536232 0.868421
7 BGC GLC GLC GLC 0.525641 0.868421
8 GLC GLC GLC GLC GLC 0.525641 0.868421
9 BGC GAL GLA 0.5 0.868421
10 BGC BGC BGC XYS 0.482353 0.871795
11 BGC BGC BGC BGC BGC BGC BGC BGC 0.474359 0.868421
12 BGC BGC BGC XYS BGC XYS XYS 0.465909 0.871795
13 BMA BMA BMA BMA GLA 0.463415 0.868421
14 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.463415 0.868421
15 FRU FRU FRU 0.459459 0.897436
16 FRU FRU FRU FRU 0.459459 0.897436
17 BGC GAL NGA GAL 0.448276 0.66
18 GLC GAL BGC FUC 0.444444 0.846154
19 BGC GAL FUC 0.444444 0.846154
20 BGC GAL SIA 0.442308 0.648148
21 BGC GAL NAG GAL 0.438202 0.66
22 BGC BGC BGC XYS BGC XYS 0.438202 0.871795
23 BMA BMA BMA BMA 0.4375 0.820513
24 BGC BGC BGC XYS XYS GAL GAL 0.43617 0.871795
25 BGC GAL NGA 0.435294 0.66
26 G4D G4D G4D G4D G4D G4D G4D G4D G4D G4D G4D 0.43038 0.846154
27 BGC BGC BGC BGC BGC XYS 0.428571 0.871795
28 BGC BGC BGC XYS BGC XYS BGC XYS BGC 0.428571 0.871795
29 BGC BGC BGC BGC XYS BGC XYS BGC BGC 0.428571 0.871795
30 BGC Z9D 0.426667 0.846154
31 BGC GAL FUC GLA 0.420455 0.846154
32 BGC GLC AGL GLC GLC GLC 0.419355 0.647059
33 BGC GAL GLA NGA GAL 0.419355 0.66
34 FRU BGC BGC BGC 0.414634 0.948718
35 GLC GLC AC1 0.4125 0.666667
36 BGC BGC BGC XYS BGC XYS XYS GAL 0.41 0.871795
37 BGC BGC BGC XYS BGC XYS XYS GAL GAL 0.41 0.871795
38 FRU GLC GLA 0.404762 0.973684
39 BGC GLA GAL 0.402778 0.868421
40 BGC GAL NAG 0.4 0.66
41 GLC FRU GLA GLA GLA 0.4 0.973684
42 GLC GLC XYS XYS 0.4 0.846154
43 GLC FRU FRU FRU 0.4 0.973684
44 G2F SHG BGC BGC 0.4 0.785714
45 GLC FRU GLA GLA 0.4 0.973684
46 ZEE UEA FRU FRU FRU 0.4 0.973684
Similar Ligands (3D)
Ligand no: 1; Ligand: GLC GLC FRU; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FMD; Ligand: GLC FRU FRU FRU; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 5fmd.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2ADD GLC FRU 12.8913
2 1Y9G FRU 16.6023
APoc FAQ
Feedback