Receptor
PDB id Resolution Class Description Source Keywords
5FBG 1.97 Å EC: 3.1.30.1 S1 NUCLEASE FROM ASPERGILLUS ORYZAE, MUTANT D65N, IN COMPLEX PHOSPHATE, 2'-DEOXYCYTIDINE AND 2'-DEOXYGUANOSINE. ASPERGILLUS ORYZAE RIB40 ENDONUCLEASE ZINC DEPENDENT COMPLEX MUTANT HYDROLASE
Ref.: STRUCTURAL AND CATALYTIC PROPERTIES OF S1 NUCLEASE ASPERGILLUS ORYZAE RESPONSIBLE FOR SUBSTRATE RECOGN CLEAVAGE, NON-SPECIFICITY, AND INHIBITION. PLOS ONE V. 11 68832 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 A:601;
B:601;
 Invalid;
Invalid;
 none;
none;
 submit data
94.971 O4 P [O-]P...
ZN A:402;
A:401;
B:403;
B:401;
A:403;
B:402;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
 submit data
65.409 Zn [Zn+2...
NAG A:502;
B:502;
B:501;
A:501;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
221.208 C8 H15 N O6 CC(=O...
GNG B:701;
 Valid;
 none;
 submit data
267.241 C10 H13 N5 O4 c1nc2...
DCZ A:701;
A:702;
 Valid;
Valid;
 none;
none;
 submit data
227.217 C9 H13 N3 O4 C1[C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FBF 1.04 Å EC: 3.1.30.1 S1 NUCLEASE FROM ASPERGILLUS ORYZAE IN COMPLEX WITH TWO MOLE 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE ASPERGILLUS ORYZAE RIB40 ENDONUCLEASE ZINC DEPENDENT COMPLEX HYDROLASE
Ref.: STRUCTURAL AND CATALYTIC PROPERTIES OF S1 NUCLEASE ASPERGILLUS ORYZAE RESPONSIBLE FOR SUBSTRATE RECOGN CLEAVAGE, NON-SPECIFICITY, AND INHIBITION. PLOS ONE V. 11 68832 2016
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5FBB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5FBC - AS C10 H14 N5 O5 P S c1nc(c2c(n....
3 5FBF - DCM C9 H14 N3 O7 P C1[C@@H]([....
4 5FBD - DCZ C9 H13 N3 O4 C1[C@@H]([....
5 5FBG - GNG C10 H13 N5 O4 c1nc2c(n1[....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5FBB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5FBC - AS C10 H14 N5 O5 P S c1nc(c2c(n....
3 5FBF - DCM C9 H14 N3 O7 P C1[C@@H]([....
4 5FBD - DCZ C9 H13 N3 O4 C1[C@@H]([....
5 5FBG - GNG C10 H13 N5 O4 c1nc2c(n1[....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5FBB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5FBC - AS C10 H14 N5 O5 P S c1nc(c2c(n....
3 5FBF - DCM C9 H14 N3 O7 P C1[C@@H]([....
4 5FBD - DCZ C9 H13 N3 O4 C1[C@@H]([....
5 5FBG - GNG C10 H13 N5 O4 c1nc2c(n1[....
6 1AK0 - ADS THS THS THS n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GNG; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 GNG 1 1
2 6CG 0.470588 0.777778
3 G2Q 0.447917 0.860759
4 C1Z 0.438776 0.833333
5 EXX 0.407895 0.746667
6 3D1 0.402597 0.873239
7 3L1 0.402597 0.873239
Ligand no: 2; Ligand: DCZ; Similar ligands found: 31
No: Ligand ECFP6 Tc MDL keys Tc
1 DCZ 1 1
2 LDC 1 1
3 DCM 0.693548 0.833333
4 DC 0.693548 0.833333
5 YYY 0.641791 0.847222
6 DCP 0.605634 0.847222
7 0KX 0.597222 0.824324
8 DCP MG 0.575342 0.84507
9 3TC 0.557377 0.893939
10 LTT 0.540984 0.907692
11 MCY 0.539683 0.954545
12 5BT 0.539683 0.926471
13 CTN 0.52459 0.907692
14 AR3 0.52459 0.907692
15 B86 0.515625 0.926471
16 GEO 0.5 0.852941
17 DUR 0.483871 0.921875
18 DKZ 0.477612 0.811594
19 I5A 0.46875 0.835821
20 C2P 0.457143 0.794521
21 C3P 0.457143 0.780822
22 DOC 0.450704 0.808219
23 3DT 0.424242 0.84058
24 THM 0.424242 0.880597
25 LLT 0.424242 0.880597
26 CPA 0.415842 0.78481
27 DCT 0.4125 0.821918
28 C 0.410959 0.77027
29 CAR 0.410959 0.77027
30 C5P 0.410959 0.77027
31 CGP 0.4 0.756098
Similar Ligands (3D)
Ligand no: 1; Ligand: GNG; Similar ligands found: 536
No: Ligand Similarity coefficient
1 2FD 0.9995
2 CL9 0.9950
3 2FA 0.9824
4 MDR 0.9809
5 GMP 0.9798
6 5F1 0.9759
7 IMG 0.9736
8 CDY 0.9718
9 8HG 0.9718
10 6CR 0.9683
11 MG7 0.9681
12 DCF 0.9662
13 4UO 0.9641
14 ADN 0.9638
15 9DI 0.9617
16 5N5 0.9605
17 FMB 0.9603
18 FMC 0.9582
19 CFE 0.9581
20 5FD 0.9565
21 7D7 0.9560
22 A4D 0.9540
23 1DA 0.9522
24 THM 0.9518
25 FTU 0.9507
26 A 0.9498
27 IMH 0.9486
28 UA2 0.9481
29 5CD 0.9479
30 PRH 0.9475
31 AD3 0.9472
32 NOS 0.9471
33 3BH 0.9458
34 5AD 0.9457
35 Y3J 0.9456
36 0DN 0.9455
37 5ID 0.9451
38 FM2 0.9442
39 6MD 0.9439
40 HPR 0.9438
41 DBM 0.9437
42 FM1 0.9433
43 3AD 0.9426
44 TBN 0.9420
45 8OX 0.9420
46 TAL 0.9419
47 RPP 0.9419
48 5BT 0.9418
49 RFZ 0.9415
50 RAB 0.9401
51 13A 0.9400
52 PUR 0.9394
53 MTP 0.9385
54 PE2 0.9384
55 MTH 0.9373
56 5MD 0.9372
57 NWW 0.9362
58 GA2 0.9358
59 MTA 0.9349
60 ARJ 0.9323
61 MTI 0.9309
62 MTM 0.9308
63 TMC 0.9297
64 XYA 0.9288
65 XTS 0.9278
66 H7S 0.9278
67 NWQ 0.9268
68 B86 0.9263
69 EKH 0.9262
70 AC2 0.9257
71 MCY 0.9249
72 5I5 0.9243
73 SNI 0.9242
74 SCT 0.9242
75 5NB 0.9238
76 26A 0.9226
77 ZYV 0.9221
78 A4V 0.9207
79 3DT 0.9206
80 CTE 0.9200
81 6ZW 0.9198
82 5V7 0.9196
83 ID2 0.9192
84 AHU 0.9175
85 F01 0.9174
86 DUR 0.9156
87 ZYW 0.9155
88 CC5 0.9148
89 2QV 0.9148
90 92O 0.9142
91 NOC 0.9142
92 5UD 0.9136
93 2QU 0.9133
94 LLT 0.9132
95 8DA 0.9128
96 MCF 0.9124
97 ZAS 0.9124
98 X2M 0.9110
99 TO1 0.9107
100 BC3 0.9092
101 HO4 0.9080
102 7CI 0.9072
103 96Z 0.9071
104 MFR 0.9067
105 XFE 0.9056
106 B5A 0.9049
107 5ER 0.9049
108 5NN 0.9041
109 DTE 0.9040
110 Q11 0.9039
111 AFX 0.9035
112 KF5 0.9032
113 HBI 0.9028
114 ZJB 0.9027
115 4ZF 0.9026
116 5JT 0.9025
117 AOJ 0.9017
118 GL6 0.9014
119 NEU 0.9010
120 BVD 0.9009
121 2UD 0.9009
122 N8M 0.9009
123 NIY 0.9006
124 DBQ 0.9002
125 X0T 0.8997
126 2L2 0.8997
127 ZIQ 0.8996
128 DG 0.8993
129 KWB 0.8991
130 1Q4 0.8986
131 5E5 0.8979
132 NEO 0.8976
133 TRP 0.8973
134 SGP 0.8973
135 DBS 0.8967
136 SGV 0.8967
137 3GX 0.8965
138 C4E 0.8965
139 3RP 0.8963
140 H4B 0.8957
141 0SY 0.8955
142 PJK 0.8953
143 AJ4 0.8953
144 ACE TRP 0.8950
145 DCZ 0.8945
146 BB4 0.8944
147 BIO 0.8944
148 II4 0.8940
149 YE7 0.8937
150 88R 0.8931
151 DXK 0.8930
152 9E3 0.8929
153 NWD 0.8929
154 5SJ 0.8926
155 HVE 0.8925
156 O9Q 0.8925
157 M01 0.8921
158 4GU 0.8918
159 ML1 0.8918
160 96U 0.8914
161 JY4 0.8914
162 WG8 0.8913
163 AGI 0.8912
164 5TZ 0.8910
165 ITW 0.8909
166 URI 0.8907
167 ZEA 0.8904
168 P2L 0.8901
169 IM5 0.8901
170 MPU 0.8900
171 PIQ 0.8900
172 5P7 0.8899
173 F40 0.8898
174 ZSP 0.8898
175 9UL 0.8896
176 CDJ 0.8896
177 LI7 0.8893
178 3WN 0.8892
179 3WO 0.8892
180 JCZ 0.8890
181 LFN 0.8890
182 9CE 0.8889
183 4Z9 0.8885
184 0J4 0.8885
185 CTN 0.8883
186 0J2 0.8883
187 JMQ 0.8883
188 MBY 0.8881
189 3GC 0.8879
190 MIL 0.8877
191 H2B 0.8877
192 78U 0.8876
193 22L 0.8873
194 MZR 0.8869
195 M3W 0.8868
196 OUA 0.8866
197 78P 0.8865
198 2P3 0.8864
199 LL1 0.8863
200 Z17 0.8862
201 5XL 0.8861
202 3Y7 0.8861
203 LUM 0.8860
204 XYP XDN 0.8859
205 XDN XYP 0.8859
206 XIF XYP 0.8855
207 XYP XIF 0.8855
208 ZRK 0.8855
209 092 0.8854
210 BZC 0.8853
211 QUE 0.8852
212 LU2 0.8851
213 JRO 0.8850
214 M02 0.8849
215 4CN 0.8849
216 CMU 0.8845
217 MUX 0.8844
218 3WK 0.8842
219 EXL 0.8842
220 5B2 0.8841
221 4AB 0.8841
222 RE4 0.8839
223 PVQ 0.8837
224 14Z 0.8837
225 M83 0.8837
226 NQ7 0.8835
227 VUP 0.8834
228 ZEZ 0.8833
229 Q5M 0.8833
230 ID8 0.8832
231 NE2 0.8830
232 P4L 0.8829
233 DGP 0.8826
234 G6P 0.8826
235 5E4 0.8824
236 57D 0.8822
237 XYP XYP 0.8821
238 2K8 0.8816
239 DTR 0.8810
240 SG2 0.8810
241 CC6 0.8809
242 833 0.8809
243 38B 0.8809
244 ETV 0.8807
245 KLV 0.8807
246 IA2 0.8806
247 1TD 0.8806
248 39Z 0.8804
249 JAK 0.8803
250 QKU 0.8802
251 3D8 0.8800
252 NEC 0.8798
253 B61 0.8797
254 ALN 0.8794
255 38E 0.8794
256 1ZC 0.8793
257 VT3 0.8793
258 XYP AHR 0.8790
259 IXG 0.8789
260 WS6 0.8788
261 7AP 0.8788
262 5P3 0.8787
263 ACK 0.8787
264 CCV 0.8786
265 A4G 0.8786
266 5GP 0.8784
267 IOP 0.8784
268 1V1 0.8784
269 PCQ 0.8782
270 RGG 0.8779
271 DIH 0.8779
272 3JC 0.8778
273 KP2 0.8778
274 1KX 0.8775
275 Z21 0.8774
276 W8L 0.8773
277 H35 0.8772
278 IOS 0.8771
279 6BK 0.8770
280 4R1 0.8769
281 BG6 0.8766
282 1QV 0.8765
283 PBQ 0.8765
284 AVX 0.8764
285 NPL 0.8763
286 5F7 0.8761
287 A73 0.8761
288 AR3 0.8761
289 THU 0.8760
290 CPW 0.8760
291 5BX 0.8759
292 EXG 0.8759
293 G 0.8759
294 PLP 0.8759
295 6J3 0.8758
296 PRL 0.8758
297 PMP 0.8758
298 FF2 0.8758
299 BJ4 0.8757
300 CGW 0.8756
301 GJK 0.8756
302 SY4 0.8754
303 50Q 0.8752
304 XYS XYP 0.8751
305 IMK 0.8751
306 M78 0.8751
307 XMP 0.8750
308 QQY 0.8750
309 ITE 0.8750
310 NU3 0.8750
311 2L1 0.8748
312 4L2 0.8747
313 QMS 0.8747
314 HRM 0.8747
315 NTF 0.8746
316 2WU 0.8745
317 AV4 0.8745
318 E9L 0.8742
319 CTD 0.8742
320 5AE 0.8742
321 APS 0.8741
322 ONZ 0.8740
323 DFL 0.8739
324 MBP 0.8737
325 ZRL 0.8736
326 XEV 0.8735
327 DDU 0.8735
328 6XC 0.8734
329 CG8 0.8734
330 7A9 0.8732
331 FER 0.8732
332 O9Z 0.8732
333 OLU 0.8732
334 4Y2 0.8731
335 CNI 0.8730
336 TDI 0.8729
337 NAR 0.8729
338 3WL 0.8727
339 BHS 0.8727
340 28B 0.8726
341 EMU 0.8726
342 HMD 0.8726
343 KMP 0.8725
344 56N 0.8724
345 EXR 0.8724
346 PVK 0.8724
347 ET0 0.8723
348 2JK 0.8723
349 20D 0.8722
350 TIA 0.8721
351 25F 0.8721
352 4VT 0.8721
353 28A 0.8720
354 7L4 0.8719
355 0DF 0.8717
356 M6P 0.8717
357 CZ0 0.8716
358 ASE 0.8716
359 H2W 0.8716
360 SGW 0.8716
361 581 0.8715
362 9OF 0.8715
363 6J9 0.8715
364 UL1 0.8713
365 BBY 0.8713
366 JO5 0.8710
367 AGV 0.8708
368 3AK 0.8708
369 GI1 0.8706
370 0GA 0.8704
371 CJZ 0.8703
372 4P8 0.8703
373 JWS 0.8701
374 HWH 0.8701
375 0OK 0.8701
376 QQX 0.8700
377 BRY 0.8695
378 L5D 0.8693
379 OUB 0.8693
380 0Q2 0.8691
381 2KU 0.8690
382 78Y 0.8689
383 IQQ 0.8688
384 M5H 0.8688
385 94M 0.8688
386 Q4G 0.8687
387 7D0 0.8687
388 L3L 0.8686
389 8G6 0.8685
390 B4O 0.8682
391 3F4 0.8682
392 49P 0.8682
393 SZ5 0.8680
394 H70 0.8680
395 FWD 0.8680
396 IDZ 0.8680
397 JF8 0.8680
398 NE1 0.8679
399 QUB 0.8678
400 S7D 0.8676
401 4WF 0.8675
402 MUK 0.8675
403 DNQ 0.8675
404 BHM 0.8674
405 FNT 0.8673
406 5WS 0.8671
407 8Y7 0.8671
408 TQU 0.8671
409 1FL 0.8670
410 1V3 0.8670
411 NXB 0.8670
412 6DQ 0.8669
413 Z8B 0.8669
414 1V4 0.8669
415 C1Y 0.8669
416 GRX 0.8668
417 XDL XYP 0.8667
418 6U5 0.8667
419 FY8 0.8663
420 D80 0.8662
421 PMM 0.8662
422 URD 0.8661
423 774 0.8661
424 CHQ 0.8661
425 Z25 0.8659
426 W29 0.8658
427 933 0.8656
428 LM7 0.8656
429 BP7 0.8656
430 KYN 0.8655
431 4F0 0.8654
432 3GP 0.8654
433 X04 0.8653
434 RNK 0.8653
435 CWD 0.8652
436 M6D 0.8650
437 QR2 0.8649
438 EAT 0.8649
439 I5A 0.8649
440 6NZ 0.8648
441 B2L 0.8647
442 22T 0.8646
443 ON1 0.8645
444 JYK 0.8644
445 D87 0.8644
446 AMP 0.8644
447 XYP XYS 0.8643
448 X48 0.8642
449 3WJ 0.8642
450 2GQ 0.8641
451 EZN 0.8640
452 WV7 0.8639
453 BWD 0.8637
454 OUG 0.8637
455 SYE 0.8635
456 MXD 0.8635
457 NKI 0.8635
458 WLH 0.8634
459 B52 0.8633
460 RGK 0.8633
461 9JT 0.8631
462 ARP 0.8631
463 4G2 0.8631
464 F5C 0.8631
465 M3Q 0.8630
466 D5M 0.8628
467 0FR 0.8625
468 IWD 0.8624
469 145 0.8624
470 PW1 0.8624
471 MYC 0.8624
472 SX3 0.8623
473 6GP 0.8622
474 A1Y 0.8621
475 2J1 0.8620
476 1DR 0.8620
477 EMO 0.8619
478 96R 0.8618
479 7ZC 0.8617
480 A5H 0.8617
481 XG1 0.8616
482 N2M 0.8616
483 0HY 0.8615
484 Q9T 0.8615
485 6TJ 0.8611
486 FQX 0.8611
487 SU9 0.8604
488 DAH 0.8603
489 G30 0.8603
490 HFT 0.8602
491 FUC GAL 0.8602
492 5WN 0.8601
493 IQZ 0.8600
494 C0H 0.8598
495 RHN 0.8598
496 GEO 0.8596
497 9B3 0.8594
498 EV2 0.8592
499 L21 0.8592
500 47V 0.8592
501 TCR 0.8588
502 51Y 0.8588
503 DX2 0.8587
504 TU0 0.8586
505 UUA 0.8585
506 AMR 0.8583
507 54X 0.8580
508 BUX 0.8575
509 8HH 0.8575
510 IMP 0.8574
511 2D2 0.8572
512 O9T 0.8572
513 2DL 0.8569
514 JO8 0.8566
515 5AV 0.8566
516 JP2 0.8565
517 53X 0.8561
518 7EH 0.8560
519 5XK 0.8559
520 CWE 0.8550
521 ANC 0.8549
522 X6P 0.8546
523 CX6 0.8538
524 CX5 0.8537
525 2LW 0.8537
526 JOV 0.8536
527 4FF 0.8536
528 UAY 0.8534
529 7VF 0.8532
530 NRA 0.8531
531 DS8 0.8528
532 DQH 0.8524
533 HA6 0.8520
534 GLP 0.8514
535 885 0.8513
536 LMZ 0.8507
Ligand no: 2; Ligand: DCZ; Similar ligands found: 598
No: Ligand Similarity coefficient
1 THU 0.9875
2 URD 0.9850
3 DDU 0.9792
4 5AE 0.9766
5 0DN 0.9766
6 CTD 0.9740
7 URI 0.9735
8 ID2 0.9701
9 5MD 0.9683
10 2TU 0.9661
11 TYU 0.9652
12 PIR 0.9578
13 UUA 0.9561
14 SCT 0.9538
15 F01 0.9521
16 DHZ 0.9512
17 ZEB 0.9491
18 TMC 0.9474
19 ANU 0.9449
20 3D1 0.9448
21 II4 0.9395
22 MDR 0.9385
23 PF1 0.9362
24 5UD 0.9359
25 5F1 0.9349
26 FPL 0.9337
27 MZR 0.9326
28 AHU 0.9304
29 C0H 0.9300
30 RBV 0.9298
31 PQT 0.9294
32 DNB 0.9290
33 RAB 0.9290
34 6HO 0.9288
35 D1Y 0.9275
36 7D7 0.9258
37 ENG 0.9251
38 FMB 0.9251
39 EN1 0.9244
40 DTY 0.9235
41 TYR 0.9235
42 9DI 0.9234
43 5AD 0.9233
44 B41 0.9231
45 ZYV 0.9230
46 PUR 0.9226
47 PFF 0.9225
48 MJ5 0.9216
49 ADN 0.9214
50 X11 0.9214
51 A 0.9210
52 BRD 0.9209
53 IMH 0.9205
54 NOS 0.9203
55 TIZ 0.9200
56 W29 0.9196
57 TBN 0.9196
58 1DA 0.9194
59 UA2 0.9192
60 0A1 0.9191
61 R9J 0.9190
62 TIA 0.9189
63 KYN 0.9185
64 E0O 0.9179
65 R9G 0.9178
66 CH8 0.9171
67 FTV 0.9161
68 HPR 0.9160
69 PRH 0.9160
70 TRP 0.9150
71 1KN 0.9145
72 YOF 0.9142
73 DBM 0.9139
74 5JT 0.9133
75 XYA 0.9131
76 DAH 0.9131
77 CK2 0.9128
78 A4D 0.9124
79 K80 0.9117
80 YF3 0.9113
81 3L1 0.9112
82 KTJ 0.9110
83 TCC 0.9105
84 FHC 0.9104
85 Y4L 0.9104
86 0GA 0.9094
87 7R7 0.9088
88 9W5 0.9087
89 7QV 0.9080
90 AD3 0.9080
91 TYE 0.9068
92 1QP 0.9063
93 TH4 0.9062
94 ISA 0.9061
95 FB4 0.9059
96 DTR 0.9058
97 EZN 0.9055
98 2GD 0.9053
99 9UL 0.9050
100 NNR 0.9046
101 ZIQ 0.9045
102 UKV 0.9041
103 ENO 0.9040
104 TCL 0.9037
105 TZM 0.9037
106 XIF XYP 0.9035
107 XYP XIF 0.9034
108 6J9 0.9027
109 0XT 0.9025
110 IYR 0.9024
111 AZZ 0.9023
112 7ZL 0.9012
113 QMR 0.9011
114 HNM 0.9011
115 MTH 0.9011
116 HNH 0.9010
117 6MD 0.9008
118 FMC 0.9006
119 N2Y 0.9006
120 L5D 0.9005
121 BPY 0.9004
122 EXR 0.9004
123 1KP 0.9001
124 DX3 0.9001
125 JRB 0.9001
126 RQD 0.9000
127 MTA 0.8996
128 RLG 0.8993
129 5ID 0.8989
130 78U 0.8989
131 15E 0.8989
132 51Y 0.8988
133 9B3 0.8986
134 CL9 0.8986
135 3BH 0.8985
136 2B4 0.8977
137 EKH 0.8977
138 HNK 0.8976
139 BVD 0.8974
140 HWD 0.8972
141 1Z6 0.8969
142 8OE 0.8969
143 CTE 0.8968
144 LL1 0.8967
145 JVQ 0.8962
146 5NB 0.8960
147 HNL 0.8956
148 69K 0.8955
149 M5H 0.8954
150 MTP 0.8952
151 A7Q 0.8946
152 FM1 0.8946
153 GNG 0.8945
154 WOE 0.8942
155 FTU 0.8938
156 RFZ 0.8937
157 CUT 0.8934
158 KP2 0.8931
159 HRM 0.8931
160 OCZ 0.8928
161 54Z 0.8928
162 N1E 0.8919
163 JWS 0.8917
164 TR7 0.8915
165 GMP 0.8915
166 4I5 0.8915
167 CMU 0.8913
168 BZE 0.8912
169 A6H 0.8911
170 BZJ 0.8911
171 DCF 0.8910
172 5I5 0.8910
173 3Y7 0.8908
174 LJ4 0.8906
175 H7S 0.8903
176 MUK 0.8903
177 CDY 0.8903
178 BQ2 0.8896
179 PH3 0.8896
180 PHE 0.8896
181 S0G 0.8895
182 4V2 0.8895
183 CH9 0.8894
184 61M 0.8894
185 EGR 0.8894
186 F63 0.8893
187 2UB 0.8891
188 L22 0.8890
189 ITW 0.8890
190 WSD 0.8890
191 LTN 0.8890
192 ANC 0.8889
193 1WC 0.8889
194 AUV 0.8885
195 J47 0.8885
196 TT4 0.8884
197 4Z1 0.8883
198 M02 0.8881
199 92G 0.8880
200 4OG 0.8879
201 79W 0.8879
202 F2W 0.8879
203 30G 0.8877
204 XDK 0.8876
205 CC5 0.8875
206 FT1 0.8874
207 8DA 0.8873
208 3QO 0.8873
209 1A7 0.8873
210 22L 0.8871
211 8OB 0.8867
212 TI7 0.8866
213 16Z 0.8866
214 S8D 0.8865
215 50C 0.8865
216 BP3 0.8863
217 ROI 0.8862
218 CFA 0.8862
219 27M 0.8861
220 7VY 0.8861
221 DBS 0.8860
222 BGU 0.8860
223 IOP 0.8859
224 9FH 0.8857
225 HBI 0.8856
226 6FB 0.8856
227 ACE TRP 0.8854
228 JZA 0.8853
229 MXD 0.8853
230 9VQ 0.8853
231 8U3 0.8853
232 CNI 0.8851
233 WL3 0.8851
234 FT2 0.8851
235 YIE 0.8851
236 PPN 0.8850
237 N0Z 0.8850
238 6QF 0.8848
239 S60 0.8846
240 XFE 0.8844
241 9FL 0.8843
242 EXL 0.8843
243 M3E 0.8843
244 FQX 0.8843
245 RVD 0.8843
246 F16 0.8840
247 2J5 0.8839
248 4BY 0.8837
249 QTV 0.8837
250 MP5 0.8836
251 CCV 0.8836
252 9BF 0.8835
253 IC9 0.8834
254 C82 0.8834
255 AWE 0.8833
256 XYP AHR 0.8832
257 GNW 0.8831
258 5E4 0.8830
259 IM4 0.8824
260 JF6 0.8824
261 DEW 0.8821
262 5F8 0.8821
263 P9E 0.8820
264 4I8 0.8818
265 GVG 0.8818
266 BP7 0.8815
267 38B 0.8815
268 IWH 0.8814
269 2K8 0.8814
270 HFA 0.8812
271 0A9 0.8812
272 MSR 0.8810
273 I2E 0.8810
274 3VW 0.8809
275 EQA 0.8808
276 JGB 0.8808
277 4G2 0.8807
278 9R5 0.8807
279 WS7 0.8804
280 HX8 0.8802
281 SY4 0.8802
282 2UD 0.8801
283 NIY 0.8799
284 FWD 0.8799
285 848 0.8799
286 L13 0.8796
287 363 0.8796
288 ING 0.8796
289 X48 0.8794
290 Q4G 0.8793
291 ETV 0.8792
292 DTE 0.8791
293 9PL 0.8790
294 6J3 0.8790
295 FDR 0.8790
296 EAJ 0.8788
297 MAJ 0.8788
298 QUS 0.8786
299 3QV 0.8785
300 STT 0.8784
301 EXG 0.8784
302 IMG 0.8784
303 WVV 0.8781
304 AMR 0.8781
305 46P 0.8778
306 HX4 0.8778
307 F4K 0.8777
308 AH9 0.8777
309 AVA 0.8776
310 5GV 0.8775
311 JY4 0.8774
312 C9E 0.8774
313 7UZ 0.8772
314 6HX 0.8771
315 ALN 0.8769
316 APS 0.8768
317 2C2 0.8768
318 NCT 0.8763
319 BZQ 0.8762
320 MPK 0.8762
321 J4K 0.8761
322 IOS 0.8760
323 A5H 0.8760
324 4UO 0.8759
325 B2T 0.8758
326 XDL XYP 0.8757
327 JOV 0.8757
328 49O 0.8756
329 SKF 0.8755
330 344 0.8755
331 C53 0.8752
332 EXD 0.8751
333 M5E 0.8748
334 S0E 0.8747
335 HVE 0.8747
336 U 0.8746
337 36E 0.8745
338 WUB 0.8745
339 IQQ 0.8744
340 Z15 0.8744
341 G14 0.8743
342 C2Y 0.8743
343 6ZW 0.8742
344 CPZ 0.8742
345 X0U 0.8741
346 1VK 0.8740
347 657 0.8740
348 BTM 0.8740
349 6DP 0.8739
350 43F 0.8739
351 CUH 0.8739
352 GWM 0.8739
353 BBY 0.8738
354 SV4 0.8737
355 M01 0.8737
356 MR6 0.8735
357 JF1 0.8735
358 PYU 0.8734
359 OA1 0.8733
360 GSY 0.8733
361 8XL 0.8732
362 BZM 0.8732
363 RUY 0.8732
364 54E 0.8732
365 EYY 0.8732
366 CWD 0.8732
367 XYP XDN 0.8732
368 H4B 0.8731
369 0OL 0.8731
370 GC3 0.8731
371 XDN XYP 0.8729
372 B4O 0.8729
373 PH2 0.8729
374 89J 0.8728
375 8D6 0.8727
376 7Q1 0.8726
377 JAH 0.8725
378 4NS 0.8724
379 ODK 0.8723
380 2F6 0.8723
381 EUE 0.8722
382 2UZ 0.8722
383 Q2S 0.8721
384 TMG 0.8721
385 0JD 0.8720
386 S24 0.8719
387 B2Y 0.8718
388 4WF 0.8717
389 M72 0.8715
390 AN3 0.8715
391 NAG 0.8714
392 78Y 0.8712
393 DHY 0.8712
394 YTX 0.8711
395 4GU 0.8711
396 BRH 0.8710
397 EVF 0.8710
398 1A5 0.8709
399 P2L 0.8709
400 NHT 0.8709
401 CSN 0.8709
402 X0W 0.8707
403 6KT 0.8707
404 BNL 0.8706
405 2WU 0.8703
406 EBP 0.8703
407 M3Q 0.8703
408 2GQ 0.8700
409 X6P 0.8699
410 CB1 0.8698
411 RVB 0.8697
412 7R4 0.8697
413 I3E 0.8697
414 A5E 0.8697
415 ZEC 0.8696
416 TLM 0.8694
417 NGT 0.8692
418 X2M 0.8691
419 ID8 0.8690
420 JG8 0.8689
421 6NT 0.8687
422 4FF 0.8687
423 BZS 0.8687
424 XCG 0.8686
425 HXY 0.8685
426 1FL 0.8685
427 S0F 0.8682
428 0UL 0.8682
429 T2D 0.8680
430 WCU 0.8679
431 OQC 0.8677
432 JF8 0.8676
433 PRL 0.8676
434 9FG 0.8675
435 977 0.8675
436 LL2 0.8675
437 EYV 0.8675
438 QMS 0.8674
439 L1T 0.8674
440 ZZZ 0.8672
441 TZF 0.8671
442 8HG 0.8670
443 FC2 0.8670
444 1F1 0.8670
445 D3G 0.8669
446 33S 0.8667
447 1SF 0.8667
448 3ZB 0.8666
449 535 0.8666
450 5F5 0.8665
451 IWT 0.8664
452 E4P 0.8664
453 TYL 0.8664
454 5GT 0.8663
455 FCD 0.8662
456 WS6 0.8658
457 DBQ 0.8658
458 428 0.8657
459 9AA 0.8655
460 FMQ 0.8655
461 VM1 0.8654
462 UA5 0.8651
463 8NX 0.8651
464 F6P 0.8651
465 JR2 0.8651
466 4BL 0.8650
467 DNQ 0.8648
468 M6H 0.8648
469 XYP XYP 0.8647
470 3NY 0.8646
471 DE3 0.8645
472 N8M 0.8645
473 4HP 0.8644
474 1FD 0.8643
475 SDF 0.8643
476 CP6 0.8643
477 PPT 0.8641
478 3CR 0.8641
479 36Y 0.8641
480 EAT 0.8640
481 23N 0.8639
482 5E5 0.8638
483 AP4 0.8638
484 MOK 0.8638
485 8VR 0.8637
486 AH6 0.8637
487 W8G 0.8636
488 NB1 0.8636
489 PAU 0.8635
490 JMS 0.8635
491 0HN 0.8635
492 SQ4 0.8634
493 HHH 0.8634
494 MPV 0.8632
495 AOJ 0.8632
496 15N 0.8631
497 SNU 0.8630
498 TJM 0.8628
499 IAC 0.8627
500 AOT 0.8623
501 5FL 0.8623
502 AZM 0.8621
503 2QC 0.8620
504 N2Z 0.8619
505 2ZM 0.8619
506 52C 0.8617
507 GNM 0.8617
508 CU8 0.8616
509 6NI 0.8616
510 ESI 0.8615
511 XI7 0.8614
512 4AU 0.8613
513 NCV 0.8613
514 CS2 0.8612
515 9ZE 0.8612
516 ISC 0.8612
517 4FP 0.8611
518 DRG 0.8611
519 G6P 0.8610
520 HA5 0.8609
521 E3X 0.8605
522 TQL 0.8604
523 U5P 0.8604
524 QBS 0.8601
525 SLS 0.8601
526 PPY 0.8599
527 ABF 0.8597
528 B21 0.8597
529 97T 0.8597
530 2LY 0.8596
531 4NP 0.8594
532 2PK 0.8592
533 AX8 0.8588
534 M1Z 0.8588
535 AJD 0.8588
536 J9Q 0.8588
537 DX1 0.8587
538 8P3 0.8587
539 GNV 0.8586
540 GVY 0.8585
541 AV4 0.8585
542 HQJ 0.8585
543 JAW 0.8584
544 JMG 0.8584
545 ESP 0.8583
546 TMP 0.8583
547 IA2 0.8582
548 14N 0.8582
549 UMP 0.8582
550 3R4 0.8581
551 6X9 0.8581
552 5NI 0.8578
553 KYA 0.8578
554 GN6 0.8577
555 46M 0.8577
556 BIO 0.8577
557 3VS 0.8576
558 PIQ 0.8575
559 YZM 0.8574
560 K48 0.8573
561 68A 0.8572
562 DU 0.8572
563 8NB 0.8570
564 LJ3 0.8570
565 4VY 0.8569
566 2O6 0.8567
567 7O4 0.8566
568 JSX 0.8563
569 PLP 0.8562
570 6TZ 0.8561
571 092 0.8560
572 5O5 0.8559
573 XRS 0.8559
574 AKD 0.8558
575 A4V 0.8558
576 XYS XYS 0.8557
577 2JM 0.8556
578 L5V 0.8554
579 R2P 0.8554
580 B23 0.8554
581 7L4 0.8553
582 JB8 0.8553
583 NGO 0.8553
584 UNJ 0.8550
585 LAH 0.8550
586 B1J 0.8549
587 ALE 0.8547
588 5OO 0.8546
589 RK4 0.8544
590 DPN 0.8531
591 2HC 0.8530
592 MZM 0.8527
593 NGW 0.8527
594 3A9 0.8526
595 L03 0.8522
596 LNR 0.8517
597 EV3 0.8513
598 Z21 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FBF; Ligand: DCM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5fbf.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5FBF; Ligand: DCM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5fbf.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
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