Receptor
PDB id Resolution Class Description Source Keywords
5FA8 1.3 Å EC: 2.-.-.- SAM COMPLEX WITH AKMT FROM THE HYPERTHERMOPHILIC ARCHAEON SU ISLANDICU SULFOLOBUS ISLANDICUS (STRAIN M.14.25 KAMCHATKA #1) PROTEIN METHYLTRANSFERASE TRANSFERASE
Ref.: AKMT CATALYZES EXTENSIVE PROTEIN LYSINE METHYLATION HYPERTHERMOPHILIC ARCHAEON SULFOLOBUS ISLANDICUS BU DISPENSABLE FOR THE GROWTH OF THE ORGANISM MOL.CELL PROTEOMICS V. 15 2908 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:301;
Valid;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
MG A:302;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FA8 1.3 Å EC: 2.-.-.- SAM COMPLEX WITH AKMT FROM THE HYPERTHERMOPHILIC ARCHAEON SU ISLANDICU SULFOLOBUS ISLANDICUS (STRAIN M.14.25 KAMCHATKA #1) PROTEIN METHYLTRANSFERASE TRANSFERASE
Ref.: AKMT CATALYZES EXTENSIVE PROTEIN LYSINE METHYLATION HYPERTHERMOPHILIC ARCHAEON SULFOLOBUS ISLANDICUS BU DISPENSABLE FOR THE GROWTH OF THE ORGANISM MOL.CELL PROTEOMICS V. 15 2908 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 5FA8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 5FAD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 5FA8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 5FAD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 5FA8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 5FAD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FA8; Ligand: SAM; Similar sites found: 276
This union binding pocket(no: 1) in the query (biounit: 5fa8.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3FUU ADN 0.0000492 0.46773 None
2 5FTW SAH 0.0003905 0.45362 None
3 4ITU 1HS 0.005306 0.42184 None
4 4ITU NAI 0.003154 0.42184 None
5 4CS9 AMP 0.03563 0.40416 None
6 5T2U NAP 0.008513 0.40354 None
7 2WSB NAD 0.004292 0.4239 1.24224
8 4FC7 COA 0.008872 0.41206 1.24224
9 4FC7 NAP 0.008872 0.41206 1.24224
10 2UYQ SAM 0.0001826 0.52552 1.86335
11 4BLW AMP 0.0001041 0.48602 1.86335
12 4BLW SAH 0.00009048 0.47723 1.86335
13 3VSE SAH 0.000003621 0.46522 1.86335
14 4YAG NAI 0.002247 0.43816 1.86335
15 4DMG SAM 0.000006381 0.56809 2.48447
16 1XCL SAH 0.00002325 0.51048 2.48447
17 3C3Y SAH 0.00008844 0.4579 2.48447
18 1P1C SAH 0.0002445 0.45395 2.48447
19 1ELI PYC 0.006137 0.41513 2.48447
20 2AE2 PTO 0.007579 0.41316 2.48447
21 2AE2 NAP 0.007579 0.41316 2.48447
22 4RSL FAD 0.00803 0.40798 2.48447
23 5U75 SIA GAL NDG FUC 0.003973 0.45539 3.10559
24 2PT9 2MH 0.0005881 0.45407 3.10559
25 2CBZ ATP 0.01328 0.42043 3.10559
26 2PNC CLU 0.02262 0.4129 3.10559
27 1YXM ADE 0.01655 0.41178 3.10559
28 1AE1 NAP 0.005485 0.41165 3.10559
29 3FZG SAM 0.0006591 0.40979 3.10559
30 2PT9 S4M 0.02312 0.4022 3.10559
31 2YY7 NAD 0.006241 0.40682 3.20513
32 4OBW SAM 0.00000653 0.54029 3.72671
33 1Q0S SAH 0.00002493 0.49628 3.72671
34 5E1M SAH 0.0001498 0.4793 3.72671
35 5E1M PRO PRO LYS ARG ILE ALA 0.0001498 0.4793 3.72671
36 2O07 SPD 0.0002703 0.46256 3.72671
37 2O07 MTA 0.000226 0.46256 3.72671
38 4R6W SAH 0.00001264 0.45143 3.72671
39 5XVK SAH 0.0003462 0.44783 3.72671
40 4RDH AMP 0.003134 0.43026 3.72671
41 1ZMD FAD 0.00426 0.42697 3.72671
42 5ITV NAI 0.00208 0.42689 3.72671
43 2F5Z FAD 0.006177 0.41988 3.72671
44 4UCI SAM 0.001182 0.41428 3.72671
45 1MO9 FAD 0.02603 0.41195 3.72671
46 4YNU FAD 0.009844 0.41186 3.72671
47 5KMS NAD 0.01684 0.4105 3.72671
48 1MO9 KPC 0.03093 0.40887 3.72671
49 4NBU NAI 0.005741 0.40835 3.72671
50 1ZMD NAI 0.004061 0.40763 3.72671
51 2BVE PH5 0.03122 0.40118 4.20168
52 1G55 SAH 0.0000004984 0.5417 4.34783
53 1VE3 SAM 0.00000737 0.53798 4.34783
54 5JJR SAH 0.00006214 0.49732 4.34783
55 5CUQ NSC 0.0001047 0.48294 4.34783
56 3TKY SAH 0.00003641 0.47253 4.34783
57 3SSO SAH 0.001082 0.4499 4.34783
58 4MO2 FDA 0.001304 0.44302 4.34783
59 4MO2 FAD 0.00178 0.43834 4.34783
60 4A6D SAM 0.002586 0.43648 4.34783
61 3MB5 SAM 0.02716 0.42162 4.34783
62 1BC5 SAH 0.001599 0.42088 4.34783
63 3NUG NAD 0.003117 0.4195 4.34783
64 4TM3 FAD 0.01933 0.41328 4.34783
65 1PN0 FAD 0.01375 0.40792 4.34783
66 1PN0 IPH 0.01433 0.40792 4.34783
67 3UOY NAP 0.02504 0.40746 4.34783
68 3UOY FAD 0.02504 0.40746 4.34783
69 1DJL NAP 0.007318 0.40633 4.34783
70 1D4O NAP 0.004897 0.40578 4.34783
71 3SK2 GRI 0.01991 0.41288 4.54545
72 5FA5 MTA 0.000001528 0.49568 4.96894
73 2BZG SAH 0.00001156 0.48234 4.96894
74 1JQD SAH 0.000614 0.44767 4.96894
75 2AOT SAH 0.00006949 0.44161 4.96894
76 2JJQ SAH 0.0000873 0.43199 4.96894
77 4X60 SFG 0.000003995 0.43001 4.96894
78 1Y8Q ATP 0.0007418 0.42859 4.96894
79 5GWX SAR 0.0003972 0.42775 4.96894
80 5GWX SAM 0.0003972 0.42775 4.96894
81 4X60 3XV 0.000004315 0.42476 4.96894
82 1JQD HSM 0.002043 0.42145 4.96894
83 4XFR CIT 0.01538 0.41955 4.96894
84 1GET FAD 0.01391 0.41873 4.96894
85 1GET NAP 0.01475 0.41873 4.96894
86 3E1T FAD 0.008327 0.41418 4.96894
87 5N9X THR 0.02049 0.40863 4.96894
88 2HBL AMP 0.03357 0.40826 4.96894
89 1PNO NAP 0.006191 0.40569 4.96894
90 3DUW SAH 0.000004712 0.50669 5.59006
91 1NW5 SAM 0.00002303 0.47849 5.59006
92 1V59 NAD 0.001309 0.45709 5.59006
93 3FRH SAH 0.0005379 0.44007 5.59006
94 3SQP FAD 0.03348 0.42852 5.59006
95 4D7E FAD 0.003068 0.42591 5.59006
96 2HQM FAD 0.005235 0.4221 5.59006
97 1IY8 NAD 0.002714 0.42203 5.59006
98 2WBV SIA 0.04469 0.41144 5.59006
99 2WPB ZZI 0.02242 0.40945 5.59006
100 4EMI FAD 0.01282 0.40127 5.59006
101 2BRY FAD 0.009924 0.40071 5.59006
102 1U2Z SAH 0.00000001397 0.62599 6.21118
103 5X62 SAH 0.000001206 0.5795 6.21118
104 1UWK URO 0.000243 0.48364 6.21118
105 1UWK NAD 0.000243 0.48364 6.21118
106 1X87 NAD 0.0001749 0.45985 6.21118
107 1EJ0 SAM 0.0002071 0.44073 6.21118
108 5IL1 SAM 0.00186 0.43248 6.21118
109 5K7U SAM 0.002446 0.42724 6.21118
110 3ICT ADP 0.009403 0.41589 6.21118
111 3GU3 SAH 0.0000002828 0.6425 6.8323
112 4XUC SAM 0.000005287 0.541 6.8323
113 4XUC 43G 0.000005287 0.541 6.8323
114 3BGD SAH 0.00002975 0.49105 6.8323
115 3C6K SPD 0.0005765 0.45702 6.8323
116 3C6K MTA 0.0005765 0.45702 6.8323
117 3BGD PM6 0.00005781 0.45189 6.8323
118 2ZWA SAH 0.001166 0.42993 6.8323
119 3LAD FAD 0.003506 0.42972 6.8323
120 2JK0 ASP 0.02538 0.40765 6.8323
121 3FPF TNA 0.00004565 0.40436 6.8323
122 3FPF MTA 0.00004565 0.40436 6.8323
123 3AB1 FAD 0.01314 0.40273 6.8323
124 1LSS NAD 0.00005204 0.49052 7.14286
125 3HVJ 705 0.00000861 0.53668 7.45342
126 5MPT SAH 0.0001572 0.47961 7.45342
127 4RL4 PPV 0.00185 0.46533 7.45342
128 4RPL 3UC 0.006891 0.43345 7.45342
129 4RPL FAD 0.007761 0.42918 7.45342
130 3EYA FAD 0.003431 0.42269 7.45342
131 1N4W FAD 0.00642 0.41914 7.45342
132 1HFU NAG NDG 0.009638 0.40651 7.45342
133 3Q87 SAM 0.00007177 0.47554 8
134 1JG3 ADN 0.0000006049 0.52897 8.07453
135 4ONQ SFG 0.00001576 0.52349 8.07453
136 2PXX SAH 0.00005028 0.49614 8.07453
137 1KYZ SAH 0.0001629 0.48393 8.07453
138 3I53 SAH 0.00002931 0.48113 8.07453
139 2WA2 SAM 0.00004313 0.45608 8.07453
140 5MX4 HPA 0.01131 0.42862 8.07453
141 2BD0 NAP 0.003098 0.42092 8.07453
142 1COY FAD 0.007268 0.41491 8.07453
143 1COY AND 0.02213 0.40443 8.07453
144 2CDU FAD 0.01007 0.40375 8.07453
145 4RDN 6MD 0.03173 0.40325 8.07453
146 5J60 FAD 0.01434 0.40107 8.07453
147 4QTU SAM 0.000007206 0.53243 8.69565
148 5THY SAH 0.0001363 0.47289 8.69565
149 3NDJ JHZ 0.0005361 0.4695 8.69565
150 3NDJ SAH 0.0005361 0.4695 8.69565
151 3O7W SAM 0.00007934 0.43478 8.69565
152 2PX8 SAH 0.0005232 0.42309 8.69565
153 5F7J ADE 0.01681 0.41797 8.69565
154 4JDR FAD 0.006427 0.41725 8.69565
155 2AJH MET 0.02128 0.41298 8.69565
156 2EG5 SAH 0.000007802 0.55659 9.31677
157 1N2X SAM 0.000006458 0.51794 9.31677
158 3A27 SAM 0.000004491 0.49756 9.31677
159 5THZ SAH 0.0001439 0.46329 9.31677
160 3VYW SAM 0.0002707 0.46033 9.31677
161 5JAQ NAI 0.001488 0.44281 9.31677
162 1RJD SAM 0.000516 0.42746 9.31677
163 4BV6 FAD 0.007626 0.414 9.31677
164 3S1S SAH 0.00008647 0.47226 9.93789
165 1D4D FAD 0.007669 0.41575 9.93789
166 3KLJ FAD 0.006407 0.40878 9.93789
167 5L95 AMP 0.001218 0.41425 10
168 4POO SAM 0.00001373 0.50685 10.559
169 1TPY SAH 0.0001064 0.47292 10.559
170 1KYQ NAD 0.002097 0.43412 10.559
171 5EB4 FAD 0.01124 0.4057 11.1801
172 2ZIF SAM 0.0000003376 0.58962 11.8012
173 4AZW SAM 0.00004755 0.46563 11.8012
174 3L9W AMP 0.00004705 0.43729 11.8012
175 3L9W GSH 0.0001284 0.43314 11.8012
176 3PT9 SAH 0.000001999 0.56286 12.4224
177 3EVG SAH 0.00001957 0.51935 12.4224
178 3JWH SAH 0.0000003994 0.50277 12.4224
179 3G89 SAM 0.000002886 0.48344 12.4224
180 3GCZ SAM 0.00001286 0.48236 12.4224
181 1L1E SAH 0.0001177 0.47559 12.4224
182 2P41 SAH 0.0000215 0.47479 12.4224
183 1EFV AMP 0.0007131 0.47205 12.4224
184 1EFV FAD 0.0007474 0.47112 12.4224
185 5JCM FAD 0.02866 0.40417 12.4224
186 5JCM NAD 0.02866 0.40417 12.4224
187 5JCM ISD 0.03352 0.4021 12.4224
188 3X0D SAH 0.0000003588 0.54694 13.0435
189 5DM1 5D7 0.00001278 0.53218 13.0435
190 5DM1 SAH 0.00001185 0.53218 13.0435
191 4FZV SAM 0.00002203 0.48683 13.0435
192 4M52 FAD 0.003621 0.4291 13.0435
193 1BZL FAD 0.02276 0.42065 13.0435
194 4X7Y SAH 0.01111 0.40685 13.0435
195 3VC1 GST 0.00003546 0.51433 13.6646
196 3VC1 SAH 0.00003546 0.51433 13.6646
197 1Z3C SA8 0.00005341 0.49199 13.6646
198 1R18 SAH 0.0002961 0.4819 13.6646
199 5M58 SAH 0.00002165 0.47859 13.6646
200 4DCM SAM 0.00001339 0.4698 13.6646
201 2JHP SAH 0.002545 0.43035 13.6646
202 2WPF FAD 0.0147 0.42937 13.6646
203 2WPF WPF 0.02151 0.42267 13.6646
204 3M6W SAM 0.0005484 0.41529 13.6646
205 5HJM MTA 0.0000001327 0.60707 14.2857
206 2DPM SAM 0.00000136 0.55119 14.2857
207 5MGZ SAH 0.00001272 0.52181 14.2857
208 3A4T SFG 0.00001132 0.51315 14.2857
209 4PIO AVI 0.00003884 0.4301 14.2857
210 4PIO SAH 0.00004189 0.42501 14.2857
211 4N49 SAM 0.002262 0.42144 14.2857
212 3GDN HBX 0.01739 0.4064 14.2857
213 3GDN FAD 0.01251 0.4064 14.2857
214 2EJU SAH 0.0000007068 0.5827 14.9068
215 1WG8 SAM 0.000001496 0.5461 14.9068
216 3GWZ SAH 0.00004189 0.44618 14.9068
217 3GXO SAH 0.0002394 0.42846 14.9068
218 4II2 ATP 0.005785 0.40422 15.3374
219 1KPG SAH 0.000111 0.46291 15.528
220 3DXY SAM 0.000001187 0.60315 16.1491
221 1QAN SAH 0.000001013 0.55648 16.1491
222 2PWY SAH 0.003857 0.43418 16.1491
223 1FEC FAD 0.007745 0.41819 16.1491
224 4M38 SAH 0.0000009371 0.53847 16.7702
225 1KPH SAH 0.00009742 0.46511 16.7702
226 1Q9I FAD 0.01459 0.41268 16.7702
227 1Q9I TEO 0.01459 0.41268 16.7702
228 1WY7 SAH 0.0000003088 0.57781 17.3913
229 5KOK S9T 0.00004674 0.5008 17.3913
230 1G60 SAM 0.000006535 0.50027 17.3913
231 5KOK SAH 0.000008706 0.49582 17.3913
232 5KOK R9T 0.0002267 0.47025 17.3913
233 1IM8 SAI 0.01136 0.40996 17.3913
234 3A25 SAM 0.00001385 0.47931 18.6335
235 3OFK SAH 0.0008347 0.43594 18.6335
236 4Y2H SAH 0.0000003653 0.59895 19.2547
237 4Y2H 49K 0.0000006732 0.58747 19.2547
238 2FK8 SAM 0.0001163 0.45673 19.2547
239 4C4A SAH 0.00000009383 0.56821 19.8758
240 1NV8 SAM 0.000004097 0.48694 19.8758
241 1NV8 MEQ 0.00001908 0.47032 19.8758
242 5U8U FAD 0.008722 0.42749 19.8758
243 1DL5 SAH 0.0000005973 0.53318 20.4969
244 2YX1 SFG 0.0000002442 0.51788 20.4969
245 3U31 NAD 0.005302 0.40271 20.4969
246 5DX1 SFG 0.0000006552 0.5631 21.118
247 5DX8 SFG 0.0000005879 0.56014 21.118
248 5DWQ SFG 0.0000006949 0.55967 21.118
249 5DX0 SFG 0.000000835 0.55879 21.118
250 5DXA SFG 0.0000006952 0.55719 21.118
251 5E8J SAH 0.00008552 0.50782 21.118
252 3G2O SAM 0.000004143 0.50077 21.118
253 2A14 SAH 0.0002689 0.44783 21.118
254 5E9W SAH 0.00008343 0.4268 21.118
255 2VDV SAM 0.0000006879 0.60606 21.7391
256 1JQ3 AAT 0.0005339 0.45451 21.7391
257 4FN4 NAD 0.002228 0.42427 21.7391
258 3EGI ADP 0.0000003352 0.65946 22.3602
259 3GDH SAH 0.0000002333 0.56627 22.3602
260 1ZQ9 SAM 0.0001357 0.44659 22.3602
261 3TLJ SAH 0.0000007396 0.5561 23.6025
262 4M73 SAH 0.000003498 0.55191 24.2236
263 4M73 M72 0.000008017 0.53801 24.2236
264 3LCC SAH 0.0000002726 0.53474 24.8447
265 1I1N SAH 0.00000005055 0.61369 26.7081
266 3DMH GMP 0.00000149 0.55285 26.7081
267 3DMH SAM 0.000000402 0.55168 26.7081
268 3GRU AMP 0.000007072 0.51634 27.3292
269 3EGV SAH 0.0000005555 0.59461 29.1925
270 4IWN GEK 0.000001114 0.54889 29.1925
271 2NXE SAM 0.0000006283 0.53226 29.1925
272 2XVM SAH 0.00001745 0.45974 29.8137
273 1XDS SAM 0.00001035 0.55083 30.4348
274 1QZZ SAM 0.00002773 0.53077 31.0559
275 3QOX SAH 0.000000002706 0.65489 37.8882
276 5MW4 5JU 0.0000009155 0.58324 37.8882
Pocket No.: 2; Query (leader) PDB : 5FA8; Ligand: SAM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5fa8.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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