Receptor
PDB id Resolution Class Description Source Keywords
5F8F 1.9 Å EC: 2.-.-.- RV2258C-SFG MYCOBACTERIUM TUBERCULOSIS H37RV METHYLTRANSFERASE CLASS I SINEFUNGIN S-ADENOSYL-L-HOMOCYSCOMPLEX TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF RV2258C FROM MYCOBACTERIUM TUB H37RV, AN S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE J.STRUCT.BIOL. V. 193 172 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SFG C:400;
B:400;
A:401;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
GOL A:403;
A:404;
A:402;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5F8F 1.9 Å EC: 2.-.-.- RV2258C-SFG MYCOBACTERIUM TUBERCULOSIS H37RV METHYLTRANSFERASE CLASS I SINEFUNGIN S-ADENOSYL-L-HOMOCYSCOMPLEX TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF RV2258C FROM MYCOBACTERIUM TUB H37RV, AN S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE J.STRUCT.BIOL. V. 193 172 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 5F8F - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 5F8F - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 5F8F - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5F8F; Ligand: SFG; Similar sites found: 399
This union binding pocket(no: 1) in the query (biounit: 5f8f.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2EJU SAH 0.0004775 0.43799 1.32626
2 3KLJ FAD 0.005783 0.4305 1.32626
3 1PN0 FAD 0.004779 0.44862 1.59151
4 1PN0 IPH 0.004969 0.44862 1.59151
5 5JJR SAH 0.0005844 0.43615 1.59151
6 3UOY NAP 0.04506 0.41056 1.59151
7 3UOY FAD 0.04506 0.41056 1.59151
8 5EZ7 FAD 0.02855 0.40318 1.59151
9 3AB1 FAD 0.02632 0.40583 1.66667
10 1G55 SAH 0.00003847 0.51112 1.74927
11 3NDJ JHZ 0.0003729 0.50262 1.85676
12 3NDJ SAH 0.0003729 0.50262 1.85676
13 1PS9 FAD 0.001221 0.47212 1.85676
14 3ICS FAD 0.002242 0.45604 1.85676
15 3ICR FAD 0.002495 0.45267 1.85676
16 4N49 SAM 0.001652 0.43938 1.85676
17 4OPC FDA 0.03347 0.42869 1.85676
18 4OPC PGT 0.03756 0.42869 1.85676
19 4MRP GSH 0.01677 0.409 1.85676
20 3TLJ SAH 0.0001963 0.42824 1.87668
21 2F5X ASP 0.02041 0.40418 1.92308
22 2P41 SAH 0.0008689 0.44792 1.96721
23 4GLL NAD 0.0114 0.41525 2.07715
24 1ZQ9 SAM 0.0005278 0.45764 2.10526
25 3PT9 SAH 0.00004017 0.50781 2.12202
26 4FZV SAM 0.0005827 0.45992 2.12202
27 2BRY FAD 0.002617 0.44694 2.12202
28 4MIG G3F 0.005927 0.4448 2.12202
29 2JB2 FAD 0.00418 0.44396 2.12202
30 2JB2 PHE 0.004387 0.44396 2.12202
31 5G3U ITW 0.005933 0.44133 2.12202
32 5G3U FDA 0.005258 0.43808 2.12202
33 4TXI FAD 0.005563 0.4301 2.12202
34 2Q7V FAD 0.006816 0.43558 2.15385
35 2WA2 SAM 0.0003011 0.46623 2.17391
36 4MO2 FDA 0.00432 0.44115 2.17391
37 4MO2 FAD 0.006883 0.4324 2.17391
38 3EVG SAH 0.0003552 0.44481 2.18182
39 3A4T SFG 0.0005145 0.41688 2.18978
40 1DL5 SAH 0.0003313 0.48044 2.2082
41 2PX8 SAH 0.0005759 0.45594 2.23048
42 5CUQ NSC 0.0001888 0.49987 2.24719
43 2O07 MTA 0.003311 0.43539 2.30263
44 2O07 SPD 0.003796 0.43539 2.30263
45 3ZNN FAD 0.02719 0.41657 2.30548
46 3ZNN 4WL 0.02719 0.41657 2.30548
47 5ITV NAI 0.001421 0.45691 2.35294
48 4FN4 NAD 0.0006301 0.47215 2.3622
49 5X62 SAH 0.000002823 0.54104 2.38727
50 2ZWA SAH 0.0000002332 0.53637 2.38727
51 3VSE SAH 0.0001463 0.46366 2.38727
52 5KMS FAD 0.009163 0.42428 2.38727
53 5KMS NAD 0.02086 0.42311 2.38727
54 3HP9 CF1 0.01007 0.42029 2.38727
55 4YNU LGC 0.0259 0.41273 2.38727
56 4YNU FAD 0.02282 0.41234 2.38727
57 4FC7 COA 0.02221 0.41124 2.38727
58 4FC7 NAP 0.02221 0.41124 2.38727
59 5JCM NAD 0.01281 0.43778 2.43902
60 5JCM ISD 0.01281 0.43778 2.43902
61 5JCM FAD 0.01246 0.43778 2.43902
62 1WG8 SAM 0.0001954 0.48747 2.45614
63 1AE1 NAP 0.004303 0.43663 2.5641
64 3A27 SAM 0.002484 0.42744 2.57353
65 3EYA FAD 0.001675 0.45867 2.65252
66 1MO9 FAD 0.01207 0.44586 2.65252
67 3NTD FAD 0.004956 0.43933 2.65252
68 2IID PHE 0.009294 0.43888 2.65252
69 2IID FAD 0.009294 0.43888 2.65252
70 3NTA FAD 0.005687 0.43642 2.65252
71 1MO9 KPC 0.01928 0.43566 2.65252
72 2EFJ SAH 0.01349 0.41915 2.65252
73 2E5V FAD 0.02959 0.40589 2.65252
74 1N2X SAM 0.0008711 0.4029 2.65781
75 2AE2 NAP 0.004901 0.44161 2.69231
76 2AE2 PTO 0.004901 0.44161 2.69231
77 1FK8 NAD 0.003281 0.43258 2.72374
78 4NBW NAD 0.00607 0.42307 2.72374
79 4NBU NAI 0.001472 0.45619 2.8
80 3CTY FAD 0.008057 0.43476 2.82132
81 3NUG NAD 0.00201 0.44978 2.83401
82 2BD0 NAP 0.0004867 0.48035 2.86885
83 3GDH SAH 0.00007071 0.43572 2.90456
84 3S1S SAH 0.0000644 0.50765 2.91777
85 5U8U FAD 0.01951 0.42836 2.91777
86 3LAD FAD 0.02026 0.41321 2.91777
87 2V3V MGD 0.04696 0.41173 2.91777
88 3NT6 FAD 0.021 0.40879 2.91777
89 2WOX NDP 0.01913 0.40672 2.91777
90 1YY5 FAD 0.008746 0.433 2.92398
91 5A3B APR 0.007652 0.41695 2.9703
92 3ABI NAD 0.00722 0.4222 3.0137
93 1Q0S SAH 0.0001072 0.49948 3.0888
94 5J60 FAD 0.007748 0.43189 3.125
95 1KPG SAH 0.0000421 0.51396 3.13589
96 1KPH SAH 0.00004211 0.51395 3.13589
97 4ZA2 NAD 0.006168 0.42411 3.16206
98 1ZMD FAD 0.00705 0.43673 3.16456
99 1ZMD NAI 0.003915 0.42901 3.16456
100 5BUK FAD 0.007137 0.43737 3.18302
101 1GET NAP 0.03841 0.41474 3.18302
102 1GET FAD 0.04075 0.4123 3.18302
103 5MZI FYK 0.03892 0.40983 3.18302
104 5M67 NAD 0.04233 0.40194 3.18302
105 2B4R AES 0.01882 0.40249 3.18841
106 2YX1 SFG 0.00004071 0.49467 3.27381
107 3EGI ADP 0.0004382 0.48524 3.39806
108 1O97 FAD 0.01874 0.42415 3.40909
109 1O97 AMP 0.01874 0.42415 3.40909
110 1E1M FAD 0.009312 0.4381 3.44828
111 1E1M NAP 0.009312 0.4381 3.44828
112 1ORR NAD 0.00246 0.44822 3.45821
113 1L1E SAH 0.00003705 0.46931 3.48432
114 3E1T FAD 0.0067 0.43782 3.51562
115 2DPM SAM 0.0002397 0.43018 3.52113
116 5E9W SAH 0.0000007848 0.55755 3.52564
117 3FRH SAH 0.000003388 0.56629 3.55731
118 4RSL FAD 0.01372 0.4158 3.59551
119 4REP FAD 0.01347 0.41919 3.63636
120 4C4A SAH 0.0002064 0.4782 3.71353
121 1V59 FAD 0.005589 0.4435 3.71353
122 1N4W FAD 0.006684 0.43787 3.71353
123 3A25 SAM 0.00154 0.43677 3.71353
124 2V3A FAD 0.01252 0.41976 3.71353
125 4GUT FAD 0.02138 0.41538 3.71353
126 4HSU FAD 0.02194 0.41319 3.71353
127 1V59 NAD 0.003512 0.40798 3.71353
128 1XDS SAM 0.00001974 0.52265 3.74332
129 3H4V DVP 0.03351 0.40236 3.81944
130 3AFN NAP 0.00705 0.4264 3.87597
131 3GCZ SAM 0.0003871 0.46367 3.90071
132 1X87 NAD 0.002045 0.43877 3.97878
133 1RSG FAD 0.008846 0.43096 3.97878
134 5FJN BE2 0.0122 0.4267 3.97878
135 5FJN FAD 0.01079 0.4267 3.97878
136 1COY FAD 0.01165 0.42415 3.97878
137 3NKS FAD 0.01656 0.41285 3.97878
138 2RGO FAD 0.01858 0.41041 3.97878
139 1RKX NAD 0.01383 0.41007 3.97878
140 4D79 ATP 0.008724 0.40292 3.98551
141 1JNR FAD 0.04943 0.41155 4
142 2XYQ SAH 0.000387 0.46368 4.09836
143 4EMI FAD 0.005965 0.43542 4.14634
144 3I53 SAH 0.00001604 0.53072 4.21687
145 1G60 SAM 0.00003028 0.51581 4.23077
146 3X0D SAH 0.000102 0.49202 4.24403
147 1UWK URO 0.006163 0.4414 4.24403
148 1UWK NAD 0.006163 0.4414 4.24403
149 4D7E FAD 0.008648 0.4255 4.24403
150 4CNK FAD 0.0124 0.41996 4.24403
151 3G5S FAD 0.01282 0.41826 4.24403
152 5MBX FAD 0.02769 0.41483 4.24403
153 5MBX SP5 0.02769 0.41483 4.24403
154 2GAG NAD 0.002153 0.45577 4.28571
155 2GAG FAD 0.02013 0.41588 4.28571
156 2GAG FOA 0.03283 0.40525 4.28571
157 4PIO SAH 0.00005441 0.52859 4.33437
158 4PIO AVI 0.0000524 0.52785 4.33437
159 1D6S MET PLP 0.01109 0.40501 4.34783
160 1D6S PLP MET 0.01093 0.4037 4.34783
161 1JQ3 AAT 0.003437 0.44129 4.39189
162 3O7W SAM 0.00000026 0.58791 4.42177
163 1KEW NAD 0.03291 0.40893 4.43213
164 1KEW TYD 0.03319 0.40803 4.43213
165 3FZG SAM 0.0000403 0.50244 4.5
166 1U2Z SAH 0.0002833 0.47815 4.50928
167 2CDU FAD 0.000849 0.47408 4.50928
168 1D4D FAD 0.003042 0.4547 4.50928
169 4IV9 FAD 0.006721 0.43491 4.50928
170 3UCL CYH 0.02122 0.42646 4.50928
171 3UCL FAD 0.02122 0.42646 4.50928
172 3UCL NAP 0.02292 0.42646 4.50928
173 1ELI PYC 0.01042 0.42263 4.50928
174 4UCI SAM 0.004875 0.4162 4.50928
175 1YXM ADE 0.00669 0.42234 4.62046
176 1NW5 SAM 0.00008766 0.49498 4.70219
177 2DKN NAI 0.003885 0.43355 4.70588
178 1YQZ FAD 0.008644 0.44329 4.77454
179 1GY8 NAD 0.02085 0.40156 4.78589
180 1RJD SAM 0.0000001281 0.6259 4.79042
181 2YY7 NAD 0.001141 0.46141 4.80769
182 3VYW SAM 0.0003709 0.4293 4.87013
183 1YC5 NCA 0.00722 0.41954 4.87805
184 5JAQ NAI 0.006573 0.43439 5.03979
185 2HQM FAD 0.01064 0.42702 5.03979
186 3WV8 ATP 0.006844 0.40953 5.04587
187 5DX1 SFG 0.00002951 0.52733 5.15759
188 5DWQ SFG 0.00003145 0.52403 5.15759
189 5DX0 SFG 0.00005735 0.51397 5.15759
190 5DXA SFG 0.00002344 0.45961 5.15759
191 5DX8 SFG 0.00003892 0.45342 5.15759
192 2UYQ SAM 0.00001528 0.565 5.16129
193 4IWN GEK 0.000001367 0.58437 5.24017
194 3CGD FAD 0.02149 0.43218 5.30504
195 3CGD COA 0.02149 0.43218 5.30504
196 3CGD NAD 0.02149 0.43218 5.30504
197 5JCA FAD 0.01564 0.41877 5.30504
198 5JCA NDP 0.02973 0.41709 5.30504
199 4P8K 38C 0.04577 0.40618 5.30504
200 4P8K FAD 0.04454 0.40618 5.30504
201 1BXK NAD 0.009796 0.41465 5.35211
202 1XG5 NAP 0.001509 0.45567 5.37634
203 3HVJ 705 0.001503 0.4633 5.42986
204 2V6G NAP 0.0006498 0.47298 5.49451
205 2JJQ SAH 0.0001816 0.46553 5.57029
206 3C6K SPD 0.001997 0.45619 5.57029
207 3C6K MTA 0.001997 0.45619 5.57029
208 4J36 1HR 0.004076 0.44845 5.57029
209 3S5W FAD 0.002388 0.44624 5.57029
210 4J36 FAD 0.00299 0.44418 5.57029
211 4JDR FAD 0.006936 0.43521 5.57029
212 4TM3 FAD 0.01866 0.4311 5.57029
213 4X9M FAD 0.01191 0.42275 5.57029
214 2Y6Q FAD 0.01203 0.41414 5.57029
215 2Y6Q I7T 0.02262 0.41414 5.57029
216 5UAO FAD 0.01645 0.41398 5.57029
217 2E7Z MGD 0.01807 0.40897 5.57029
218 4D42 NAP 0.02737 0.41227 5.67376
219 4D42 W0I 0.02737 0.41227 5.67376
220 4Y2H SAH 0.000193 0.50886 5.68182
221 4Y2H 49K 0.0004557 0.49074 5.68182
222 3D3W NAP 0.0006186 0.47679 5.7377
223 1PR9 NAP 0.0006679 0.4752 5.7377
224 4YSX FAD 0.01355 0.42 5.76923
225 1QAN SAH 0.00001306 0.47285 5.83554
226 4J1Q NDP 0.002236 0.44336 5.83554
227 1I8T FAD 0.004493 0.44244 5.83554
228 4C3Y FAD 0.005884 0.43871 5.83554
229 4C3Y ANB 0.007829 0.43711 5.83554
230 3MJE NDP 0.006116 0.42561 5.83554
231 4DMG SAM 0.0005143 0.46377 5.85242
232 4DCM SAM 0.00001477 0.52175 5.86667
233 1S7G NAD 0.01771 0.40494 5.92885
234 5FA5 MTA 0.00008868 0.48728 6
235 5T2U NAP 0.007397 0.4254 6.04839
236 2IVF MGD 0.00863 0.42762 6.07477
237 4GQB 0XU 0.02269 0.44358 6.12245
238 3CIF G3H 0.0247 0.40135 6.12813
239 3CIF NAD 0.01703 0.4007 6.12813
240 4YRY FAD 0.0173 0.4166 6.15942
241 4YRY NAD 0.02651 0.4151 6.15942
242 2WSB NAD 0.001235 0.4708 6.29921
243 1VQW FAD 0.004307 0.43662 6.36605
244 2GVC FAD 0.004726 0.43469 6.36605
245 2XVE FAD 0.01441 0.43263 6.36605
246 3QFA FAD 0.01668 0.41738 6.36605
247 4M38 SAH 0.00007773 0.49962 6.41399
248 4M37 SAH 0.01622 0.41886 6.41399
249 1LSS NAD 0.0009104 0.41433 6.42857
250 3H8V ATP 0.001884 0.43284 6.50685
251 2FK8 SAM 0.00002406 0.52273 6.60377
252 4EUE NAI 0.001015 0.46521 6.6313
253 3Q9T FAY 0.02144 0.40739 6.6313
254 1BC5 SAH 0.00003671 0.51884 6.69145
255 1JJV ATP 0.02098 0.40171 6.79612
256 3QOX SAH 0.0002352 0.48185 6.89655
257 4YDD MD1 0.04778 0.41133 6.90691
258 4YDD MGD 0.04778 0.41133 6.90691
259 4USR FAD 0.01271 0.41415 6.92521
260 3CH6 NAP 0.005235 0.45576 6.99301
261 3CH6 311 0.005235 0.45576 6.99301
262 4J56 FAD 0.01169 0.42676 7.01754
263 3VC1 SAH 0.00001483 0.56435 7.05128
264 3VC1 GST 0.00001483 0.56435 7.05128
265 4RPL 3UC 0.001537 0.4864 7.1618
266 4RPL FAD 0.002604 0.47262 7.1618
267 4ONQ SFG 0.0006591 0.4338 7.1618
268 2BZG SAH 0.00003376 0.51119 7.32759
269 2YVJ FAD 0.009233 0.42518 7.33945
270 3OID NDP 0.005403 0.43191 7.36434
271 3QWI CUE 0.006482 0.43665 7.40741
272 3QWI NAP 0.00405 0.43665 7.40741
273 3ML1 MGD 0.01704 0.43427 7.40741
274 3F8D FAD 0.0399 0.41442 7.43034
275 4ITU NAI 0.002066 0.45183 7.43494
276 4ITU 1HS 0.003325 0.45183 7.43494
277 5L95 AMP 0.001745 0.43636 7.5
278 1G8K MGD 0.02801 0.42192 7.5188
279 3AYI FAD 0.00829 0.43989 7.62829
280 3AYI HCI 0.008581 0.43989 7.62829
281 5MW4 5JU 0.001263 0.47032 7.78443
282 2F5Z FAD 0.006577 0.43821 7.8125
283 2Z3Y F2N 0.01268 0.42414 7.95756
284 2VVM FAD 0.02166 0.41 7.95756
285 2B4Q NAP 0.00312 0.4394 7.97101
286 5K7U SAM 0.0009811 0.44556 8
287 4X7Y SAH 0.01028 0.42683 8.0292
288 3BGD SAH 0.000008889 0.47698 8.07692
289 3BGD PM6 0.00005377 0.42597 8.07692
290 5XVK SAH 0.00003096 0.52223 8.09859
291 1XSE NDP 0.002239 0.45821 8.13559
292 1WY7 SAH 0.00007064 0.44818 8.21256
293 5HSA FAS 0.009992 0.42744 8.22281
294 2EG5 SAH 0.00002699 0.5165 8.33333
295 4RDH AMP 0.008226 0.40009 8.33333
296 2A14 SAH 0.00009016 0.49887 8.36502
297 3FUU ADN 0.00004181 0.50949 8.48806
298 5IL1 SAM 0.0006146 0.43527 8.49057
299 4AZW SAM 0.00002349 0.52079 8.75332
300 1NV8 SAM 0.0005647 0.47287 8.80282
301 1NV8 MEQ 0.0005583 0.47153 8.80282
302 1XCL SAH 0.006201 0.42785 8.93617
303 4BLW AMP 0.01239 0.4158 8.99654
304 4BLW SAH 0.01283 0.40506 8.99654
305 5E8J SAH 0.000001386 0.57494 9.09091
306 5GWX SAR 0.00002676 0.44031 9.15493
307 5GWX SAM 0.00002676 0.44031 9.15493
308 5XLX SAH 0.00006321 0.49898 9.21986
309 1NFQ NAI 0.02123 0.40233 9.23077
310 3SSO SAH 0.001512 0.46652 9.28382
311 2PT9 2MH 0.00325 0.44367 9.34579
312 2PT9 S4M 0.002106 0.4415 9.34579
313 2VDV SAM 0.00001273 0.53128 9.34959
314 2AG5 NAD 0.00405 0.43406 9.34959
315 1IY8 NAD 0.0007184 0.47092 9.3633
316 4J7U NAP 0.006451 0.4377 9.375
317 4J7U YTZ 0.006451 0.4377 9.375
318 1Z6Z NAP 0.003396 0.43767 9.57447
319 4XUC SAM 0.0009556 0.4691 9.63303
320 4XUC 43G 0.0009556 0.4691 9.63303
321 1QZZ SAM 0.00001235 0.53188 9.81432
322 1EJ0 SAM 0.0002019 0.47635 10
323 1EFV FAD 0.03404 0.41156 10.1961
324 1EFV AMP 0.03903 0.40851 10.1961
325 5GT9 NAP 0.003689 0.4373 10.2662
326 5OCA 9QZ 0.01641 0.42603 10.3175
327 3TKY SAH 0.00000201 0.56896 10.3261
328 5HJM MTA 0.0002636 0.44296 10.5114
329 3C3Y SAH 0.0002639 0.47338 10.5485
330 1P1C SAH 0.005725 0.41823 10.5528
331 5THQ NDP 0.003801 0.43536 10.6618
332 3BMQ NAP 0.01489 0.40733 11.1111
333 5K6A NAP 0.01492 0.40728 11.1111
334 4CM9 NAP 0.01656 0.40513 11.1111
335 3JQF NAP 0.01695 0.40465 11.1111
336 4CME NAP 0.01627 0.40425 11.1111
337 5KOK S9T 0.0000003742 0.63194 11.1406
338 5KOK R9T 0.000002261 0.59286 11.1406
339 5KOK SAH 0.0000007542 0.58817 11.1406
340 4EIP FAD 0.02247 0.41268 11.1406
341 1KYZ SAH 0.00002715 0.50059 11.2329
342 3G89 SAM 0.000007153 0.52652 11.245
343 3DXY SAM 0.00003049 0.52075 11.4679
344 4QTU SAM 0.000001025 0.53619 11.5385
345 5THZ SAH 0.000007625 0.55014 12.2016
346 5THY SAH 0.000006795 0.54765 12.2016
347 4Q9N NAI 0.02022 0.40219 12.4161
348 4OBW SAM 0.00004382 0.48203 12.4514
349 5MPT SAH 0.000001334 0.54396 12.4668
350 3GWZ SAH 0.000008882 0.52408 13.0081
351 3GXO SAH 0.000047 0.49948 13.0081
352 4YAG NAI 0.002648 0.45668 13.1488
353 5FTW SAH 0.000001852 0.51701 13.2812
354 3GRU AMP 0.0001263 0.49424 13.8983
355 3DUW SAH 0.0007014 0.45423 13.9013
356 1E6E FAD 0.007128 0.42955 14.0625
357 2ZIF SAM 0.0002406 0.44413 14.1414
358 4POO SAM 0.00171 0.44405 15
359 3VC3 C6P 0.00805 0.41298 15.1163
360 3G2O SAM 0.00002676 0.51572 15.3846
361 1Z3C SA8 0.00002574 0.53756 15.7718
362 2WET FAD 0.0146 0.41934 15.9151
363 1JG3 ADN 0.0003612 0.46502 16.1804
364 2PXX SAH 0.0000002534 0.55907 16.2791
365 1IM8 SAI 0.01092 0.42908 16.3934
366 3GU3 SAH 0.0000003669 0.61916 16.5493
367 3JWH SAH 0.00000001645 0.62649 16.5899
368 3DMH GMP 0.0001258 0.50176 17.0604
369 3DMH SAM 0.00008983 0.49677 17.0604
370 4M73 M72 0.00002554 0.54873 17.2107
371 4M73 SAH 0.00003249 0.54227 17.2107
372 3QVP FAD 0.03182 0.40432 18.5676
373 4R6W SAH 0.000008958 0.42864 18.6047
374 5DM1 5D7 0.000002291 0.60237 18.7266
375 5DM1 SAH 0.000002131 0.60237 18.7266
376 1TPY SAH 0.00006071 0.5067 18.8153
377 2NXE SAM 0.00125 0.44083 20.0787
378 3EGV SAH 0.001439 0.42574 20.0787
379 3OFK SAH 0.00003344 0.46762 20.3704
380 4II2 ATP 0.002372 0.40124 20.4819
381 5E1M SAH 0.00002946 0.54132 21.1618
382 5E1M PRO PRO LYS ARG ILE ALA 0.00002946 0.54132 21.1618
383 3AD8 NAD 0.006205 0.43021 21.6749
384 3AD8 PYC 0.03702 0.41448 21.6749
385 3AD8 FAD 0.03702 0.41448 21.6749
386 4A6D SAM 0.001128 0.47588 21.813
387 3LCC SAH 0.0000007191 0.58309 22.1277
388 3Q87 SAM 0.0002111 0.484 23.5294
389 2XVM SAH 0.00000008197 0.60919 24.1206
390 5MGZ SAH 0.000005182 0.51218 24.1525
391 5M58 SAH 0.000005655 0.54869 24.3478
392 2CFC NAD 0.007501 0.42011 24.4
393 1R18 SAH 0.0003244 0.4735 24.6696
394 1I1N SAH 0.0001849 0.49394 24.7788
395 1VE3 SAM 0.000007661 0.51381 26.8722
396 2AOT SAH 0.00003282 0.50639 29.1096
397 1JQD SAH 0.0001362 0.50348 29.1096
398 1JQD HSM 0.000339 0.47998 29.1096
399 2V3B FAD 0.01017 0.42314 36.3636
Pocket No.: 2; Query (leader) PDB : 5F8F; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5f8f.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5F8F; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5f8f.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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