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Receptor
PDB id Resolution Class Description Source Keywords
5F7V 1.4 Å NON-ENZYME: OTHER ABC SUBSTRATE-BINDING PROTEIN LMO0181 FROM LISTERIA MONOCYTO COMPLEX WITH CYCLOALTERNAN LISTERIA MONOCYTOGENES SEROVAR 1/2A (SATCC BAA-679 / EGD-E) SUBSTRATE-BINDING PROTEIN STRUCTURAL GENOMICS CENTER FOR SGENOMICS OF INFECTIOUS DISEASES CSGID CYCLOALTERNAN BINDIPROTEIN
Ref.: STRUCTURE TO FUNCTION OF AN ALPHA-GLUCAN METABOLIC THAT PROMOTES LISTERIA MONOCYTOGENES PATHOGENESIS. NAT MICROBIOL V. 2 16202 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GLC GLC GLC GLC A:501;
Valid;
Atoms found LESS than expected: % Diff = 0;
Kd ~ 2 uM
648.564 n/a OCC1O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5F7V 1.4 Å NON-ENZYME: OTHER ABC SUBSTRATE-BINDING PROTEIN LMO0181 FROM LISTERIA MONOCYTO COMPLEX WITH CYCLOALTERNAN LISTERIA MONOCYTOGENES SEROVAR 1/2A (SATCC BAA-679 / EGD-E) SUBSTRATE-BINDING PROTEIN STRUCTURAL GENOMICS CENTER FOR SGENOMICS OF INFECTIOUS DISEASES CSGID CYCLOALTERNAN BINDIPROTEIN
Ref.: STRUCTURE TO FUNCTION OF AN ALPHA-GLUCAN METABOLIC THAT PROMOTES LISTERIA MONOCYTOGENES PATHOGENESIS. NAT MICROBIOL V. 2 16202 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5F7V Kd ~ 2 uM GLC GLC GLC GLC n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5F7V Kd ~ 2 uM GLC GLC GLC GLC n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5F7V Kd ~ 2 uM GLC GLC GLC GLC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GLC GLC GLC GLC; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 GLC GLC GLC GLC 1 1
2 RCD 0.510638 0.939394
3 BCD 0.510638 0.939394
4 GLC GLC GLC GLC GLC GLC 0.510638 0.939394
5 GLC GLC GLC GLC GLC GLC GLC 0.510638 0.939394
6 GLC GLC GLC GLC GLC GLC GLC GLC 0.510638 0.939394
7 ACX 0.510638 0.939394
8 4PW 0.5 0.777778
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5F7V; Ligand: GLC GLC GLC GLC; Similar sites found with APoc: 49
This union binding pocket(no: 1) in the query (biounit: 5f7v.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 2C91 TLA 1.77515
2 4KYS VIB 2
3 2OS2 OGA 2.3622
4 2YBP 2HG 2.3622
5 2Q8E OGA 2.55682
6 2P5B OGA 2.55682
7 3JU6 ANP 2.7027
8 2E40 LGC 2.75
9 3ZJX BOG 2.76817
10 4CME KTZ 2.77778
11 4TS1 TYR 3.1348
12 6FA4 D1W 3.46821
13 3ESS 18N 3.47826
14 4RF7 ARG 3.5
15 2VGD XYP XYP 3.66972
16 3SAO DBH 3.75
17 4WOE ADP 4
18 2XIQ 5AD 4.25
19 4FIL 0UE 4.5977
20 2YKL NLD 4.62963
21 4WUJ FMN 4.7619
22 6CAM BGC 4.80226
23 6EK3 OUL 4.97738
24 6GNO XDI 5.18518
25 5TDF ADE 5.25
26 5GZZ GSH 5.5
27 1QKQ MAN 5.6338
28 5LDQ NAP 5.64972
29 4GN8 ASO 5.68562
30 1IK4 PGH 5.92105
31 2E5Y ATP 6.01504
32 3OPT AKG 6.70241
33 3M3E GAL A2G NPO 6.8323
34 4O1F THG 6.89655
35 2ET1 GLV 7.46269
36 4R3U 5AD 7.59494
37 4M1U A2G MBG 8.57143
38 4WVW SLT 9.02778
39 3H0L ADP 9.57447
40 5T9C G3P 10.0746
41 3U6W KIV 10.5
42 1SR9 KIV 10.5
43 1VHW ADN 11.4625
44 4IRX INS 11.4865
45 43CA NPO 15.3846
46 2UVJ ADA ADA ADA 16.75
47 2GH9 MLR 25.1295
48 2ZYK GLC GLC GLC GLC GLC GLC GLC GLC 36.0201
49 3K00 MTT 42.75
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