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Receptor
PDB id Resolution Class Description Source Keywords
5EWS 2 Å NON-ENZYME: BINDING SUGAR BINDING PROTEIN - HUMAN GALECTIN-2 HOMO SAPIENS LACTOSE GALECTIN SUGAR BINDING PROTEIN
Ref.: HUMAN GALECTIN-2 INTERACTS WITH CARBOHYDRATES AND P NON-CLASSICALLY: NEW INSIGHT FROM X-RAY CRYSTALLOGR HEMAGGLUTINATION. ACTA BIOCHIM. BIOPHYS. SIN. V. 48 939 2016 (SHANGHAI)
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GAL BGC G:201;
N:201;
H:201;
I:201;
C:201;
M:201;
D:201;
J:201;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
342.297 n/a O(C1C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DG2 1.61 Å NON-ENZYME: BINDING SUGAR BINDING PROTEIN - HUMAN GALECTIN-2 (DIMER) HOMO SAPIENS HUMAN GALECTIN-2 SUGAR BINDING PROTEIN
Ref.: HUMAN GALECTIN-2 INTERACTS WITH CARBOHYDRATES AND P NON-CLASSICALLY: NEW INSIGHT FROM X-RAY CRYSTALLOGR HEMAGGLUTINATION. ACTA BIOCHIM. BIOPHYS. SIN. V. 48 939 2016 (SHANGHAI)
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 5DG2 - GAL GLC n/a n/a
2 5EWS - GAL BGC n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 5DG2 - GAL GLC n/a n/a
2 5EWS - GAL BGC n/a n/a
50% Homology Family (109)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5ODY Kd = 7.5 nM 9SK C30 H28 F5 N3 O11 S c1cc(c(c2c....
13 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
14 4R9D - LAT C12 H22 O11 C([C@@H]1[....
15 1KJL Kd = 67 uM GAL NAG n/a n/a
16 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
17 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
18 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
19 4R9C - LAT C12 H22 O11 C([C@@H]1[....
20 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
21 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
22 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
23 6EOL Kd = 0.037 uM BKH C20 H16 Cl2 F3 N3 O4 S c1cc(c(cc1....
24 6G0V Kd = 166 uM EGZ C18 H25 N O13 S C1[C@H](NC....
25 3AYE - LAT C12 H22 O11 C([C@@H]1[....
26 6EOG Kd = 1.6 uM BKK C20 H17 Cl F3 N3 O4 S c1cc(cc(c1....
27 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
28 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
29 2NMO Kd = 260 uM GAL BGC n/a n/a
30 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
31 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
32 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
33 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
34 5OAX Kd = 12 nM 9Q5 C30 H30 F3 N3 O11 S c1cc(cc(c1....
35 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
36 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
37 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
38 1G86 - NEQ C6 H7 N O2 CCN1C(=O)C....
39 1QKQ - MAN C6 H12 O6 C([C@@H]1[....
40 1HDK - PMB C6 H5 Hg O3 S c1cc(ccc1S....
41 2D6N - GAL NAG n/a n/a
42 2D6M - LBT C12 H22 O11 C([C@@H]1[....
43 2D6O - NAG GAL GAL NAG n/a n/a
44 4XBN Kd = 93 uM GAL NAG n/a n/a
45 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
46 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
47 5DG2 - GAL GLC n/a n/a
48 5EWS - GAL BGC n/a n/a
49 5NM1 - LBT C12 H22 O11 C([C@@H]1[....
50 5NLD - LBT C12 H22 O11 C([C@@H]1[....
51 5NMJ - LBT C12 H22 O11 C([C@@H]1[....
52 5NLH - LBT C12 H22 O11 C([C@@H]1[....
53 5NLE - LBT C12 H22 O11 C([C@@H]1[....
54 4XBL Kd = 340 uM GAL NAG n/a n/a
55 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
56 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
57 3OY8 Kd = 220 uM GAL GCO n/a n/a
58 2EAL - GAL NGA A2G n/a n/a
59 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
60 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
61 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
62 2ZHM - NAG GAL GAL NAG GAL n/a n/a
63 2EAK - LBT C12 H22 O11 C([C@@H]1[....
64 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
65 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
66 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
67 4XBQ Kd = 270 uM GAL NAG n/a n/a
68 6A62 - LAT C12 H22 O11 C([C@@H]1[....
69 6A64 - LAT C12 H22 O11 C([C@@H]1[....
70 6A63 - LAT C12 H22 O11 C([C@@H]1[....
71 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
72 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
73 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
74 3VKO - SIA GAL NAG n/a n/a
75 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
76 5T7T Kd = 2.1 uM GAL NAG n/a n/a
77 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
78 3WV6 - GAL BGC n/a n/a
79 3NV2 - GAL NDG n/a n/a
80 3NV4 - SIA GAL BGC n/a n/a
81 3NV3 - GAL NAG MAN n/a n/a
82 3WUD Kd = 41 uM GLC GAL n/a n/a
83 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
84 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
85 2GAL - GAL C6 H12 O6 C([C@@H]1[....
86 4GAL - GAL BGC n/a n/a
87 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
88 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
89 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
90 5GAL - NAG GAL n/a n/a
91 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
92 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
93 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
94 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
95 5DUX Kd = 380 uM LAT FUC n/a n/a
96 4WVV - LBT C12 H22 O11 C([C@@H]1[....
97 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
98 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
99 5CBL - LAT C12 H22 O11 C([C@@H]1[....
100 4YM0 Kd = 510 uM LAT NAG GAL n/a n/a
101 4YM2 Kd = 1400 uM SGA BGC n/a n/a
102 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
103 4YM1 Kd = 580 uM LAT FUC n/a n/a
104 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
105 1WLD - GAL BGC n/a n/a
106 6FOF - LAT C12 H22 O11 C([C@@H]1[....
107 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
108 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
109 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GAL BGC; Similar ligands found: 333
No: Ligand ECFP6 Tc MDL keys Tc
1 GLA GLA 1 1
2 GAL BGC 1 1
3 GLC GAL 1 1
4 BMA GAL 1 1
5 LBT 1 1
6 BGC GAL 1 1
7 CBI 1 1
8 MAL 1 1
9 CBK 1 1
10 BGC BMA 1 1
11 N9S 1 1
12 MAB 1 1
13 LAT 1 1
14 GLA GAL 1 1
15 B2G 1 1
16 BMA BMA BMA 0.909091 1
17 GLA GAL GLC 0.909091 1
18 GLC BGC BGC 0.909091 1
19 GLC BGC BGC BGC 0.909091 1
20 GLC GLC GLC GLC GLC 0.909091 1
21 CT3 0.909091 1
22 BGC GLC GLC GLC 0.909091 1
23 BGC BGC BGC BGC 0.909091 1
24 CTT 0.909091 1
25 CTR 0.909091 1
26 GLC GAL GAL 0.909091 1
27 MAN BMA BMA BMA BMA BMA 0.909091 1
28 BGC BGC BGC GLC 0.909091 1
29 CEY 0.909091 1
30 B4G 0.909091 1
31 BGC BGC BGC 0.909091 1
32 GLC GLC BGC 0.909091 1
33 CE5 0.909091 1
34 BGC BGC BGC BGC BGC BGC 0.909091 1
35 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
36 BMA BMA BMA BMA BMA BMA 0.909091 1
37 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
38 GLA GAL BGC 0.909091 1
39 MLR 0.909091 1
40 MAN BMA BMA 0.909091 1
41 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
42 BMA BMA BMA BMA BMA 0.909091 1
43 BGC BGC GLC 0.909091 1
44 MAN MAN BMA BMA BMA BMA 0.909091 1
45 BGC GLC GLC 0.909091 1
46 BGC BGC BGC BGC BGC 0.909091 1
47 MT7 0.909091 1
48 GLC BGC BGC BGC BGC 0.909091 1
49 CE6 0.909091 1
50 MTT 0.909091 1
51 CE8 0.909091 1
52 MAN BMA BMA BMA BMA 0.909091 1
53 GLC BGC GLC 0.909091 1
54 DXI 0.909091 1
55 GLC BGC BGC BGC BGC BGC 0.909091 1
56 CEX 0.909091 1
57 GAL GAL GAL 0.909091 1
58 BMA MAN BMA 0.909091 1
59 BGC GLC GLC GLC GLC 0.909091 1
60 GLA GAL GAL 0.816327 1
61 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
62 BMA BMA GLA BMA BMA 0.689655 1
63 XYT 0.685185 0.767442
64 LAT GLA 0.680851 1
65 GLC GLC GLC BGC 0.672414 1
66 U63 0.647059 0.891892
67 MMA MAN 0.64 0.942857
68 DR5 0.64 0.942857
69 GLA EGA 0.634615 0.942857
70 GAL FUC 0.615385 0.941176
71 2M4 0.612245 1
72 BGC GAL FUC 0.610169 0.970588
73 FUC GAL GLC 0.610169 0.970588
74 8B7 0.610169 0.970588
75 GLC GAL FUC 0.610169 0.970588
76 LAT FUC 0.610169 0.970588
77 BGC GLA GAL FUC 0.609375 0.970588
78 BQZ 0.608696 0.909091
79 BGC GAL NAG GAL 0.606061 0.733333
80 GAL NAG GAL GLC 0.606061 0.733333
81 BMA BMA BMA BMA 0.603448 0.941176
82 M3M 0.6 1
83 LB2 0.6 1
84 NGR 0.6 1
85 MAN GLC 0.6 1
86 MAL EDO 0.592593 0.942857
87 BGC BGC BGC XYS GAL 0.588235 0.942857
88 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
89 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
90 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
91 LAT NAG GAL 0.588235 0.733333
92 GLC GAL NAG GAL 0.588235 0.733333
93 NGA GAL BGC 0.587302 0.733333
94 TRE 0.581395 1
95 ABD 0.57971 0.75
96 NLC 0.578947 0.733333
97 NDG GAL 0.578947 0.733333
98 GAL NDG 0.578947 0.733333
99 5GO 0.578947 0.66
100 DEL 0.574074 0.970588
101 MVP 0.571429 0.733333
102 GAL NGA GLA BGC GAL 0.571429 0.733333
103 GAL BGC BGC XYS 0.569231 0.942857
104 SGA BGC 0.568965 0.66
105 BGC BGC 0.566038 0.914286
106 BMA BMA 0.566038 0.914286
107 GLC GLC XYP 0.557377 1
108 BGC BGC XYS BGC 0.552239 0.942857
109 NAG GAL BGC 0.552239 0.733333
110 GLA GAL BGC 5VQ 0.551724 0.891892
111 G2F BGC BGC BGC BGC BGC 0.55 0.868421
112 GLA MBG 0.54902 0.942857
113 GLC ACI G6D BGC 0.547945 0.733333
114 GLC G6D ACI GLC 0.547945 0.733333
115 GLC ACI GLD GLC 0.547945 0.733333
116 GLC G6D ADH GLC 0.547945 0.733333
117 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
118 BGC BGC BGC GLC BGC BGC 0.545455 1
119 BMA BMA MAN 0.535714 1
120 MAN MAN BMA 0.535714 1
121 NGA GLA GAL BGC 0.535211 0.733333
122 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
123 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
124 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
125 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
126 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
127 BMA MAN MAN MAN 0.525424 1
128 GLA GAL GLC NBU 0.52459 0.846154
129 FUC BGC GAL 0.52459 0.970588
130 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.733333
131 GLC ACI GLD GAL 0.519481 0.702128
132 GLC ACI G6D GLC 0.519481 0.702128
133 BGC BGC BGC FRU 0.516129 0.868421
134 DOM 0.509091 0.942857
135 G3I 0.507937 0.767442
136 LMU 0.507937 0.785714
137 DMU 0.507937 0.785714
138 UMQ 0.507937 0.785714
139 OXZ BGC BGC 0.507937 0.6875
140 G2I 0.507937 0.767442
141 LMT 0.507937 0.785714
142 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
143 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
144 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
145 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
146 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
147 FMO 0.5 0.868421
148 MAN BMA NAG 0.5 0.733333
149 SOR GLC GLC 0.5 0.970588
150 GLA GAL NAG 0.5 0.733333
151 8VZ 0.5 0.673469
152 ACR GLC GLC GLC 0.493827 0.702128
153 GLC GLC DAF BGC 0.493827 0.702128
154 GLC GLC ACI G6D GLC GLC 0.493827 0.702128
155 ARE 0.493827 0.733333
156 GLC GLC AGL HMC GLC 0.493827 0.702128
157 AAO 0.493827 0.733333
158 GLC GLC XYS 0.492308 0.970588
159 MAN BMA MAN 0.491803 1
160 CGC 0.491525 0.941176
161 5QP 0.491228 0.885714
162 GAL MBG 0.490909 0.942857
163 MDM 0.490909 0.942857
164 RZM 0.490909 0.688889
165 M13 0.490909 0.942857
166 GAL NAG MAN 0.485294 0.733333
167 SOR GLC GLC GLC 0.484848 0.970588
168 GLO GLC GLC GLC 0.484848 0.970588
169 6UZ 0.484848 0.846154
170 LAG 0.484848 0.6
171 GAL BGC NAG GAL 0.478873 0.733333
172 GTM BGC BGC 0.477612 0.868421
173 10M 0.477612 0.733333
174 MAN MAN MAN MAN 0.476923 1
175 MAN MAN BMA MAN 0.476923 1
176 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
177 GAL GAL SO4 0.47619 0.66
178 NAG BMA 0.47619 0.653061
179 GAL NGA 0.47541 0.733333
180 A2G GAL 0.47541 0.733333
181 GAL A2G 0.47541 0.733333
182 GLA BMA 0.472727 1
183 GLC BGC 0.472727 1
184 GAL GAL 0.472727 1
185 GLA GLC 0.472727 1
186 BGC GLA 0.472727 1
187 GAL GLC 0.472727 1
188 GLA BGC 0.472727 1
189 BMA GLA 0.472727 1
190 BMA MAN 0.472727 1
191 MAN MAN 0.472727 1
192 BGC GLC 0.472727 1
193 MLB 0.472727 1
194 GLC GLC 0.472727 1
195 MAN BMA 0.472727 1
196 LAK 0.472727 1
197 NPJ 0.470588 0.622642
198 FUC GAL NAG GAL BGC 0.469136 0.717391
199 GAL GLC NAG GAL FUC 0.469136 0.717391
200 GLC NAG GAL GAL FUC 0.469136 0.717391
201 MAN MAN MAN GLC 0.46875 1
202 ABL 0.466667 0.702128
203 FRU GAL 0.465517 0.842105
204 BMA FRU 0.465517 0.842105
205 DAF BGC 0.464789 0.733333
206 DAF GLC 0.464789 0.733333
207 TM6 0.463768 0.916667
208 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
209 LSE 0.462687 0.6875
210 FUC GLA GLA 0.460317 0.970588
211 GAL GAL FUC 0.460317 0.970588
212 FUC GAL GLA 0.460317 0.970588
213 GLA GLA FUC 0.460317 0.970588
214 GLA GAL FUC 0.460317 0.970588
215 IFM BMA 0.457627 0.711111
216 9MR 0.457627 0.744186
217 IFM BGC 0.457627 0.711111
218 BMA IFM 0.457627 0.711111
219 BGC OXZ 0.457627 0.666667
220 RCB 0.457143 0.622642
221 GLO GLC GLC 0.457143 0.942857
222 MAN MAN MAN 0.45614 1
223 GLC GLC GLC GLC BGC 0.45614 1
224 GLC GLC GLC GLC GLC BGC 0.45614 1
225 BMA MAN MAN 0.45614 1
226 GLC GLC GLC 0.45614 1
227 WOO 0.454545 0.848485
228 GIV 0.454545 0.848485
229 BGC 0.454545 0.848485
230 ALL 0.454545 0.848485
231 GAL 0.454545 0.848485
232 GLA 0.454545 0.848485
233 GLC 0.454545 0.848485
234 GXL 0.454545 0.848485
235 BMA 0.454545 0.848485
236 MAN 0.454545 0.848485
237 ACI GLD GLC GAL 0.453333 0.733333
238 DAF BGC GLC 0.453333 0.733333
239 DAF GLC GLC 0.453333 0.733333
240 MGL SGC BGC BGC 0.450704 0.868421
241 MGL SGC GLC GLC 0.450704 0.868421
242 CM5 0.450704 0.891892
243 MAN MAN MAN BMA MAN 0.450704 1
244 BGC BGC SGC MGL 0.450704 0.868421
245 MAN MNM 0.45 0.702128
246 GLC DMJ 0.45 0.695652
247 A2G GAL BGC FUC 0.45 0.717391
248 NOJ GLC 0.45 0.695652
249 NOY BGC 0.45 0.702128
250 BMA MAN MAN MAN MAN 0.449275 1
251 GCS GCS 0.448276 0.767442
252 PA1 GCS 0.448276 0.767442
253 M5S 0.447761 1
254 MAN BMA MAN MAN MAN 0.447761 1
255 TXT 0.447368 0.767442
256 GAC 0.447368 0.767442
257 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
258 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
259 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
260 NAG GAL GAL NAG GAL 0.445946 0.6875
261 NAG GAL GAL NAG 0.445946 0.6875
262 MA4 0.444444 0.891892
263 QV4 0.444444 0.733333
264 MAN DGO 0.440678 0.914286
265 3SA 0.44 0.733333
266 Z6J 0.439024 0.742857
267 GLC GLC GLC PO4 SGC GLC 0.439024 0.66
268 AHR 0.439024 0.742857
269 RIB 0.439024 0.742857
270 FUB 0.439024 0.742857
271 32O 0.439024 0.742857
272 T6P 0.438596 0.767442
273 MMA 0.4375 0.857143
274 MBG 0.4375 0.857143
275 GYP 0.4375 0.857143
276 AMG 0.4375 0.857143
277 MAN G63 0.435484 0.653061
278 GDQ GLC 0.435484 0.666667
279 4MU BGC BGC 0.434211 0.767442
280 ISX 0.433333 0.761905
281 MAN 7D1 0.431034 0.888889
282 ACR 0.43038 0.733333
283 QPS 0.43038 0.733333
284 GAL MGC 0.428571 0.702128
285 4MU BGC BGC BGC BGC 0.428571 0.767442
286 GAL NDG FUC 0.422535 0.717391
287 FUC NDG GAL 0.422535 0.717391
288 HMC AGL GLC 0.421053 0.717391
289 KHO 0.421053 0.888889
290 GCS GCS GCS 0.419355 0.767442
291 GCS GCS GCS GCS GCS 0.419355 0.767442
292 GCS GCS GCS GCS GCS GCS 0.419355 0.767442
293 GAL NAG GAL 0.418919 0.702128
294 NGT GAL 0.41791 0.66
295 GAL NGT 0.41791 0.66
296 P3M 0.41791 0.767442
297 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
298 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
299 TUR 0.416667 0.842105
300 BTU 0.416667 0.842105
301 GLC FRU 0.416667 0.842105
302 GLA MAN ABE 0.414286 0.916667
303 NAG NAG BMA 0.413333 0.634615
304 NAG NDG BMA 0.413333 0.634615
305 ACR GLC GLC GLC GLC 0.4125 0.702128
306 ACR GLC 0.4125 0.702128
307 AHR AHR AHR AHR AHR AHR 0.410714 0.857143
308 FUB AHR AHR 0.410714 0.857143
309 VAM 0.409836 0.868421
310 GLF B8D 0.409836 0.775
311 DAF GLC DAF GLC GLC 0.409639 0.702128
312 ACI GLD GLC ACI G6D BGC 0.409639 0.702128
313 AC1 GLC AC1 BGC 0.409639 0.702128
314 ACI G6D GLC ACI G6D BGC 0.409639 0.702128
315 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.702128
316 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.702128
317 MAN MMA MAN 0.409091 0.942857
318 FUB AHR 0.407407 0.857143
319 AHR AHR 0.407407 0.857143
320 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.653061
321 4U0 0.406593 0.66
322 BGC BGC SSG PIH 0.405063 0.767442
323 GLA MAN RAM ABE 0.405063 0.891892
324 G1P 0.403846 0.697674
325 GL1 0.403846 0.697674
326 XGP 0.403846 0.697674
327 M1P 0.403846 0.697674
328 GLC IFM 0.403226 0.727273
329 MAN IFM 0.403226 0.727273
330 MAN MAN MAN MAN MAN MAN MAN 0.402597 1
331 XZZ BGC BGC 0.402439 0.702128
332 ACG 0.402299 0.695652
333 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DG2; Ligand: GAL GLC; Similar sites found with APoc: 401
This union binding pocket(no: 1) in the query (biounit: 5dg2.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5UR6 8KM None
2 2GJ5 VD3 None
3 3MTX PGT None
4 4ZSI GLP None
5 3ZO7 K6H None
6 2BWA GLC BGC None
7 2BOS GLA GAL None
8 4QRH 0O2 None
9 2FR3 REA None
10 2BOS GLA GAL GLC None
11 4ZSI 4R1 None
12 1QCA FUA None
13 3AKK ADP None
14 3X1Z GNP None
15 4KVG GTP None
16 2BYC FMN None
17 1YRX FMN None
18 5C8W PCG None
19 1EX7 5GP None
20 3TYZ PAB 1.48148
21 3TYZ XHP 1.48148
22 3BJK CIT 1.48148
23 1NE6 SP1 1.48148
24 5M42 FMN 1.48148
25 5ISY NAD 1.48148
26 5B09 4MX 1.92308
27 2QL9 CIT 2.06186
28 1TT8 PHB 2.22222
29 3N0Y APC 2.22222
30 5C3R AKG 2.22222
31 5C3R HMU 2.22222
32 5EOB 5QQ 2.22222
33 2WA4 069 2.22222
34 4HIA FMN 2.22222
35 4OFG PCG 2.22222
36 5HXI FAD 2.22222
37 5HXI 5HN 2.22222
38 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 2.22222
39 4WUJ FMN 2.22222
40 5DX9 T6P 2.22222
41 2IRY DGT 2.22222
42 2OBD 2OB 2.22222
43 5N0L ILE 2.22222
44 4YGF AZM 2.22222
45 4WW8 VD9 2.22222
46 2CER PGI 2.24949
47 5H5A 6OU 2.3166
48 2QZT PLM 2.7027
49 1QIN GIP 2.96296
50 3DLG GWE 2.96296
51 5NKB 8ZT 2.96296
52 5ZTN CUR 2.96296
53 2AG4 LP3 2.96296
54 2AG4 OLA 2.96296
55 3T1A 5MA 2.96296
56 1I82 BGC BGC 2.96296
57 2ZRU FMN 2.96296
58 5X8G S0N 2.96296
59 4RF7 ARG 2.96296
60 4BG4 ADP 2.96296
61 2GC0 PAN 2.96296
62 3AAQ ARU 2.96296
63 5YU3 PRO 2.96296
64 5YU3 NAD 2.96296
65 4ORM 2V6 2.96296
66 4ORM ORO 2.96296
67 4ORM FMN 2.96296
68 2R40 EPH 2.96296
69 4R38 RBF 2.96296
70 4BVM VCA 3.00752
71 4BVM PLM 3.00752
72 2Z6C FMN 3.10078
73 3MPB FRU 3.25203
74 5FXD H7Y 3.7037
75 5EW9 5VC 3.7037
76 2E56 MYR 3.7037
77 4U03 GTP 3.7037
78 4U03 TLL 3.7037
79 1GP6 QUE 3.7037
80 1GP6 DH2 3.7037
81 1GP6 SIN 3.7037
82 4MP8 MLI 3.7037
83 4MP8 NAD 3.7037
84 5F2T PLM 3.7037
85 5KJZ PCG 3.7037
86 2AXR ABL 3.7037
87 1AJ0 PH2 3.7037
88 1AJ0 SAN 3.7037
89 4ZLU ADP 3.7037
90 4ZLU 4PW 3.7037
91 3TAY MN0 3.7037
92 3T64 DU3 3.7037
93 5DXI TRE 3.7037
94 1LVG 5GP 3.7037
95 3UN3 G16 3.7037
96 3BXO UPP 3.7037
97 3BZ3 YAM 3.7037
98 5FBN 5WF 3.7037
99 1GQG DCD 3.7037
100 5IH9 6BF 3.7037
101 5AYT L6Y 3.7037
102 3W68 VIV 3.7037
103 6CC0 EWM 3.7037
104 3GNP SOG 3.7037
105 4WOE ADP 3.7037
106 1R5L VIV 3.7037
107 5KWY C3S 3.7594
108 3TCT 3MI 3.93701
109 5FKP 6UL 4.44444
110 3RJY GLC 4.44444
111 3G08 FEE 4.44444
112 1Q79 3AT 4.44444
113 4XCB HY0 4.44444
114 2CET PGI 4.44444
115 3L9R L9R 4.44444
116 1OPK P16 4.44444
117 3E2M E2M 4.44444
118 5IXG OTP 4.44444
119 4J7H TRH 4.44444
120 4WHZ 3NL 4.44444
121 2VFT SOR 4.44444
122 5N87 N66 4.44444
123 5KD6 6C7 4.44444
124 5KD6 LBU 4.44444
125 5EH0 5NW 4.44444
126 1E8G FAD 4.44444
127 3HMO STU 4.44444
128 4NMC 2OP 4.44444
129 4NMC FAD 4.44444
130 3W8X FAD 4.44444
131 1E8G FCR 4.44444
132 1E96 GTP 4.44444
133 3SBD GNP 4.44444
134 5LUN OGA 4.44444
135 5LUN ARG 4.44444
136 1YVD GNP 4.44444
137 1Z0J GTP 4.44444
138 3GC8 B45 4.44444
139 5KO1 6UY 4.44444
140 5N2D 8J8 4.44444
141 5ZM4 AKG 4.44444
142 4D06 NAR 4.44444
143 1DZK PRZ 4.44444
144 3H5N ATP 4.44444
145 1HE1 GDP 4.44444
146 3NKV GNP 4.44444
147 3RAB GNP 4.44444
148 4ZU4 4TG 4.44444
149 5FLJ QUE 4.44444
150 4MZU TYD 4.44444
151 4ZOA IFM 4.44444
152 5NIU 8YZ 4.6875
153 5FU3 BGC BGC BGC 4.71698
154 5N2F 8HW 4.83871
155 4BVA T3 5.18518
156 3MF2 AMP 5.18518
157 5WL0 21G 5.18518
158 4OPC PGT 5.18518
159 4OPC FDA 5.18518
160 3E8N ATP 5.18518
161 3E8N VRA 5.18518
162 5AMV ADA ADA ADA 5.18518
163 5A65 TPP 5.18518
164 3PTQ NFG 5.18518
165 1VYF OLA 5.18518
166 3SLS 77D 5.18518
167 4WW7 AMP 5.18518
168 4KBA 1QM 5.18518
169 3VHE 42Q 5.18518
170 5XEG AKG 5.18518
171 1ERB ETR 5.18518
172 3EXS 5RP 5.18518
173 4ZU5 THM 5.18518
174 3UH0 TSB 5.18518
175 6MPT C30 5.18518
176 4IAW LIZ 5.18518
177 3IAL PR8 5.18518
178 5XQW 8EU 5.18518
179 4AG8 AXI 5.18518
180 4WN5 MVC 5.21739
181 1OPB RET 5.22388
182 5KEW 6SB 5.31915
183 1OGZ EQU 5.6
184 4H2X G5A 5.82524
185 6D61 4AA 5.92593
186 3PQB VGP 5.92593
187 2Q0D ATP 5.92593
188 1TOI HCI 5.92593
189 3STD MQ0 5.92593
190 3FW4 CAQ 5.92593
191 4HSJ 6PC 5.92593
192 4XF6 ADP 5.92593
193 4XF6 LIP 5.92593
194 4XF6 INS 5.92593
195 2R5V HHH 5.92593
196 1IIU RTL 5.92593
197 5H2D ERG 5.92593
198 3VOT ADP 5.92593
199 3ILR SGN 5.92593
200 3ILR IXD 5.92593
201 3RMK BML 5.92593
202 4H6Q FAD 5.92593
203 4H6Q TFB 5.92593
204 3F5O UOC COA 5.92593
205 1EWJ BLM 6.34921
206 3GWL FAD 6.60377
207 4IGH FMN 6.66667
208 4IGH 1EA 6.66667
209 4IGH ORO 6.66667
210 3PFG TLO 6.66667
211 3PFG SAM 6.66667
212 4KYS VIB 6.66667
213 5YBN AKG 6.66667
214 2J3M PRI 6.66667
215 4U0W 16G 6.66667
216 5W0N UPU 6.66667
217 2J3M ATP 6.66667
218 5TPV TYD 6.66667
219 3KFF XBT 6.66667
220 3KFF ZBT 6.66667
221 3ZXR IQ1 6.66667
222 4X6F 3XU 6.66667
223 4RFR RHN 6.66667
224 4RD0 GDP 6.66667
225 1MH5 HAL 6.66667
226 3ETH ATP 6.66667
227 5FQK 6NT 6.66667
228 3QT6 2P0 6.66667
229 4HWS 1B3 6.66667
230 1NYW DAU 6.66667
231 5GXU FAD 6.66667
232 1KOR SIN 6.66667
233 1VRP ADP 6.66667
234 2A1L PCW 6.66667
235 1KOR ARG 6.66667
236 1KOR ANP 6.66667
237 3X0Y FMN 6.66667
238 3ZXR P3S 6.66667
239 4D1J DGJ 6.66667
240 5O9W AKG 6.66667
241 3F5K CE5 6.66667
242 2Z77 HE7 6.66667
243 1KQW RTL 6.71642
244 2P7Q GG6 6.76692
245 5U98 1KX 7.07071
246 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 7.14286
247 4M1U A2G MBG 7.14286
248 5OO5 UUA 7.25806
249 3QUZ QUV 7.40741
250 4D5B ACX 7.40741
251 4J36 1HR 7.40741
252 3WDX BGC BGC GLC 7.40741
253 6EWZ APC 7.40741
254 3PUR 2HG 7.40741
255 3FON VAL ASN ASP ILE PHE GLU ALA ILE 7.40741
256 2I74 MAN MAN MAN MAN 7.40741
257 5KF6 TFB 7.40741
258 5KF6 FAD 7.40741
259 4YVN EBS 7.40741
260 5M77 7K2 7K3 7.40741
261 1KWK GAL 7.40741
262 1R27 MGD 7.40741
263 5OX6 A1Z 7.40741
264 2BPM 529 7.40741
265 5JSP DQY 7.40741
266 6EYT UDP 7.40741
267 3A6T 8OG 7.75194
268 5UC4 83S 8.14815
269 3E8T UQ8 8.14815
270 1ZNY GDP 8.14815
271 2YG2 S1P 8.14815
272 3AXX CBI 8.14815
273 3TNF GNP 8.14815
274 1KZN CBN 8.14815
275 3WYF GTP 8.14815
276 4MJ0 BGC SIA SIA GAL 8.14815
277 4MJ0 SIA SIA GAL 8.14815
278 2F3R G5P 8.14815
279 5EQU 5R6 8.19672
280 3OGV PTQ 8.88889
281 5VC5 96M 8.88889
282 3HAZ FAD 8.88889
283 5DQ8 FLF 8.88889
284 1QZY TDE 8.88889
285 5CFT 51G 8.88889
286 2E0P CTT 8.88889
287 5NBW 8SK 8.88889
288 2PFC PLM 8.88889
289 3CXO 3LR 8.88889
290 5EZU MYR 8.98876
291 5IXH OTP 9.62963
292 4OAV ACP 9.62963
293 5W10 CMP 9.62963
294 4MNS 2AX 9.62963
295 1ST0 GTG 9.62963
296 1SDW IYT 9.62963
297 1GT4 UNA 9.62963
298 4MUV PCG 9.62963
299 4O1P ANP 9.62963
300 1F3D TPM 9.62963
301 6FA4 D1W 9.82659
302 2YJ0 420 10.1449
303 5EO8 TFU 10.3704
304 1VA6 P2S 10.3704
305 6EOZ AKG 10.3704
306 6EOZ 58K 10.3704
307 1ZM1 BGC BGC BGC 10.3704
308 1VA6 ADP 10.3704
309 2RDQ AKG 10.3704
310 1XIM XYL 10.3704
311 2ART LPA AMP 10.3704
312 4UOZ GLA 10.3704
313 4IE6 UN9 10.3704
314 2FCU AKG 10.3704
315 4ONA UW1 10.3704
316 1UU6 BGC BGC BGC BGC 10.3704
317 1ODM ASV 11.1111
318 4WVO 3UZ 11.1111
319 4LA7 A1O 11.1111
320 5HA0 LTD 11.1111
321 3B1Q NOS 11.1111
322 1CX4 CMP 11.1111
323 5LJB RTL 11.1111
324 3VSV XYP 11.1111
325 5JKG 6LF 11.1111
326 2RG0 CBI 11.1111
327 5JJU AMP 11.1111
328 1TU3 GNP 11.1111
329 3DJV C3P 11.2903
330 6E08 NAP 11.8519
331 6GNO XDI 11.8519
332 1URX AAL GAL AAL GLA 11.8519
333 4P25 FUC GAL NAG FUC 11.8519
334 4OJ8 AKG 11.8519
335 4P8K 38C 11.8519
336 4P8K FAD 11.8519
337 3RI1 3RH 11.8519
338 5TBM 79A 12.1739
339 3L5R 47X 12.2951
340 5FPX GLY SER SER HIS HIS HIS HIS HIS 12.3894
341 1U0A BGC BGC BGC BGC 12.5926
342 5OCG 9R5 12.5926
343 1NF3 GNP 12.5926
344 1ZB6 GST 12.5926
345 1ZB6 DIN 12.5926
346 3JU6 ANP 12.5926
347 5X7Q GLC GLC GLC GLC GLC 12.5926
348 3CQD ATP 12.5926
349 2NGR GDP 12.5926
350 5MZI FAD 12.5926
351 5MZI FYK 12.5926
352 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 13.3333
353 3EKK GS2 13.3333
354 2XXP DSL 13.3333
355 3B6R ADP 13.3333
356 4WTR BGC BGC 13.3333
357 1UUO ORO 13.3333
358 1UUO BRF 13.3333
359 1UUO FMN 13.3333
360 2YNE YNE 13.3333
361 2YNE NHW 13.3333
362 3E85 BSU 14.0741
363 4RYV ZEA 14.0741
364 4NPL AKG 14.0741
365 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 14.0741
366 5BU3 4W9 14.0741
367 4O8A FAD 14.0741
368 3MJH GTP 14.7059
369 5ENQ 5QE 14.8148
370 1MH1 GNP 14.8148
371 3ZJX BOG 14.8148
372 4HDO GNP 14.8148
373 5EPQ OLA 15.5556
374 3SHR CMP 15.5556
375 3AGC RCC 15.5556
376 1YKD CMP 15.5556
377 5JAX 6J7 15.5556
378 3TPV ADE 15.5556
379 4KU7 PCG 15.5556
380 1SQI 869 15.5556
381 3TKL GTP 15.5556
382 4NV7 COA 16.2963
383 2WKQ GTP 16.2963
384 3W9R A8S 16.2963
385 1EM6 CP4 17.037
386 1LFO OLA 17.1875
387 1N5S ADL 17.8571
388 1N1D C2G 19.3798
389 3VV1 GAL FUC 20
390 3QP8 HL0 20.7407
391 3RUG DB6 21.4815
392 1KGI T4A 22.0472
393 1S4M LUM 22.2222
394 3M3E GAL A2G NPO 25.9259
395 3OZ2 OZ2 26.6667
396 3VQ2 LP4 LP5 MYR DAO 27.4074
397 1UNB AKG 31.8519
398 1UNB PN1 31.8519
399 1UMZ BGC BGC XYS BGC XYS GAL 33.3333
400 5E2N V14 35.5556
401 4HDQ GNP 42.3077
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