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Receptor
PDB id Resolution Class Description Source Keywords
5E9W 2.28 Å EC: 2.1.1.56 CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE O LIMITED PROTEOLYSIS HOMO SAPIENS MRNA CAPPING TRANSFERASE
Ref.: MOLECULAR BASIS OF RNA GUANINE-7 METHYLTRANSFERASE ACTIVATION BY RAM. NUCLEIC ACIDS RES. V. 44 10423 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH B:501;
A:500;
C:501;
D:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5E9W 2.28 Å EC: 2.1.1.56 CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE O LIMITED PROTEOLYSIS HOMO SAPIENS MRNA CAPPING TRANSFERASE
Ref.: MOLECULAR BASIS OF RNA GUANINE-7 METHYLTRANSFERASE ACTIVATION BY RAM. NUCLEIC ACIDS RES. V. 44 10423 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5E9W - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5E9W - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5E9W - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5E9W; Ligand: SAH; Similar sites found with APoc: 951
This union binding pocket(no: 1) in the query (biounit: 5e9w.bio4) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1LSS NAD None
2 1MID LAP None
3 1H5Q NAP None
4 2JAH NDP 0.809717
5 2Q0L FAD 0.96463
6 3G2O SAM 1.00334
7 4DMG SAM 1.01781
8 3SJU NDP 1.07527
9 2WYV NAD 1.14943
10 3L9W AMP 1.28205
11 3L9W GSH 1.28205
12 3NJ4 AFX 1.28205
13 3NJ4 NAD 1.28205
14 3OZ2 FAD 1.28205
15 5XWV 8H6 1.28205
16 5XWV NDP 1.28205
17 1F8F NAD 1.28205
18 1U8X NAD 1.28205
19 1C0I FAD 1.28205
20 1C0I BE2 1.28205
21 1FL2 FAD 1.29032
22 4Q9N NAI 1.34228
23 4RDI ATP 1.38889
24 5K6A NAP 1.38889
25 4RDH AMP 1.38889
26 4CM9 NAP 1.38889
27 3BMN NAP 1.38889
28 5JDI NAP 1.38889
29 4CMI NAP 1.38889
30 3JQ9 NAP 1.38889
31 4CLO NAP 1.38889
32 3JQ7 NAP 1.38889
33 4CME NAP 1.38889
34 4CM8 NAP 1.38889
35 5JCJ NAP 1.38889
36 3BMO NAP 1.38889
37 4CM4 NAP 1.38889
38 4CLR NAP 1.38889
39 3JQ8 NAP 1.38889
40 5JDC NAP 1.38889
41 3JQF NAP 1.38889
42 3JQG NAP 1.38889
43 3BMQ NAP 1.38889
44 3JQA NAP 1.38889
45 3JQB NAP 1.38889
46 2JL1 NAP 1.39373
47 4D79 ATP 1.44928
48 2PD4 NAD 1.45455
49 2PD4 DCN 1.45455
50 5THQ NDP 1.47059
51 4ITU 1HS 1.48699
52 4ITU NAI 1.48699
53 2VZ0 D64 1.49254
54 2VZ0 NAP 1.49254
55 2WD7 NAP 1.49254
56 2DTX BMA 1.51515
57 4V3I ASP LEU THR ARG PRO 1.55642
58 5J60 FAD 1.60256
59 5TUF FAD 1.60256
60 3NYC IAR 1.60256
61 3NYC FAD 1.60256
62 2B9W FAD 1.60256
63 4PLT OXM 1.60256
64 1RM4 NDP 1.60256
65 1UP7 NAD 1.60256
66 4PLT NAI 1.60256
67 1P3D UMA 1.60256
68 1P31 EPU 1.60256
69 5L53 NAP 1.60256
70 2O4C NAD 1.60256
71 4URF NAD 1.6129
72 1UXG FUM 1.61812
73 1UXG NAD 1.61812
74 3A25 SAM 1.66113
75 1XHL NDP 1.6835
76 5Y8L HUI 1.69492
77 5Y8L NAD 1.69492
78 3O7W SAM 1.70068
79 3U4C NDP 1.77936
80 3WXB NDP 1.79211
81 3DUW SAH 1.79372
82 6F9Q NAD 1.83824
83 2DT5 NAD 1.89573
84 6C8R SAH 1.92308
85 6C8R EQV 1.92308
86 3QJ4 FAD 1.92308
87 1SQF SAM 1.92308
88 1YQZ FAD 1.92308
89 3HDY FDA 1.92308
90 3HDY GDU 1.92308
91 3HDY FAD 1.92308
92 3NKS FAD 1.92308
93 6GAR FAD 1.92308
94 4K5S FAD 1.92308
95 4K5S PM0 1.92308
96 3SQP FAD 1.92308
97 4X9M FAD 1.92308
98 2VVL FAD 1.92308
99 2VVM FAD 1.92308
100 1GET NAP 1.92308
101 1GET FAD 1.92308
102 2V3V MGD 1.92308
103 6F3M NAD 1.92308
104 6CEP OXM 1.92308
105 6CEP NAD 1.92308
106 1X7D ORN 1.92308
107 5ZI2 NAD 1.92308
108 1X7D NAD 1.92308
109 5ZI2 ADP 1.92308
110 1KOL NAD 1.92308
111 2UYQ SAM 1.93548
112 5EJ2 NAD 1.94805
113 1E1M NAP 1.95652
114 1E1M FAD 1.95652
115 2Q2V NAD 1.96078
116 3ORF NAD 1.99203
117 1D7O NAD 2.0202
118 1D7O TCL 2.0202
119 2JAP NDP 2.02429
120 1PR9 NAP 2.04918
121 4CQM NAP 2.04918
122 2BD0 NAP 2.04918
123 3D3W NAP 2.04918
124 3H8V ATP 2.05479
125 1ZQ9 SAM 2.10526
126 5OCQ CIT 2.10526
127 1XG5 NAP 2.15054
128 2BGM NAJ 2.15827
129 1BDB NAD 2.16606
130 1AE1 NAP 2.1978
131 4KRG SAH 2.24359
132 5U19 827 2.24359
133 5U19 SAH 2.24359
134 5YF1 8V0 2.24359
135 5YF1 SFG 2.24359
136 5T67 JHZ 2.24359
137 5T67 SAH 2.24359
138 2IVD FAD 2.24359
139 2PT9 S4M 2.24359
140 2PT9 2MH 2.24359
141 1G55 SAH 2.24359
142 4ZCC FAD 2.24359
143 4ZCC NAI 2.24359
144 4LWP SAH 2.24359
145 2XVF FAD 2.24359
146 5U8U FAD 2.24359
147 5BUK FAD 2.24359
148 4USR FAD 2.24359
149 6AIN FAD 2.24359
150 1RLZ NAD 2.24359
151 2RGO FAD 2.24359
152 3V1U NAD 2.24359
153 4HXY NDP 2.24359
154 3KLJ FAD 2.24359
155 2HQM FAD 2.24359
156 3G5S FAD 2.24359
157 2GN4 NDP 2.24359
158 3T31 FAD 2.24359
159 3T31 DCQ 2.24359
160 2A8X FAD 2.24359
161 5A1T OXM 2.24359
162 4M52 FAD 2.24359
163 3NT6 FAD 2.24359
164 3NTA FAD 2.24359
165 1RJW ETF 2.24359
166 3NTD FAD 2.24359
167 2GN4 UD1 2.24359
168 5L4S NAP 2.24359
169 5L4S 6KX 2.24359
170 1R37 NAD 2.24359
171 1GV0 NAD 2.25806
172 5V8E CIT 2.26537
173 3MAG SAH 2.28013
174 4OSP NAP 2.28137
175 1G60 SAM 2.30769
176 3BGD PM6 2.30769
177 3BGD SAH 2.30769
178 2DKN NAI 2.35294
179 3MCT SAH 2.3569
180 3FRH SAH 2.37154
181 6B92 SAH 2.38095
182 5EEH P9P 2.39362
183 5EEH SAH 2.39362
184 3B1F NAD 2.41379
185 1EDO NAP 2.45902
186 1G0N PHH 2.4735
187 1G0N NDP 2.4735
188 5KVA SAM 2.51799
189 5X62 SAH 2.5641
190 5ICE 2H4 2.5641
191 5ICE SAH 2.5641
192 4DCM SAM 2.5641
193 2IID PHE 2.5641
194 2IID FAD 2.5641
195 1FP2 SAH 2.5641
196 4PIO AVI 2.5641
197 4PIO SAH 2.5641
198 6C5B SAH 2.5641
199 1REO FAD 2.5641
200 3GWZ SAH 2.5641
201 4AP3 FAD 2.5641
202 4AP3 NAP 2.5641
203 5TS5 FAD 2.5641
204 3TKY SAH 2.5641
205 4N49 SAM 2.5641
206 1FP2 HMO 2.5641
207 4B63 FAD 2.5641
208 4B63 NAP 2.5641
209 4B63 ORN 2.5641
210 3NUG NAD 2.5641
211 4D04 NAP 2.5641
212 4D04 FAD 2.5641
213 3GXO SAH 2.5641
214 5KMS NAD 2.5641
215 4Z24 FAD 2.5641
216 2BRY FAD 2.5641
217 2RAB NAD 2.5641
218 2RAB FAD 2.5641
219 5KMS FAD 2.5641
220 1LVL NAD 2.5641
221 2NYA MGD 2.5641
222 4XQC NAD 2.5641
223 4XQC 13D 2.5641
224 1GY8 NAD 2.5641
225 5TUK FAD 2.5641
226 1WVG APR 2.5641
227 5E72 SAM 2.5641
228 1LVL FAD 2.5641
229 5UR0 NAD 2.5641
230 3FWN ATR 2.5641
231 1DLJ UGA 2.5641
232 1DLJ NAI 2.5641
233 3GGO NAI 2.5641
234 3GGO ENO 2.5641
235 1GR0 NAD 2.5641
236 1RPN NDP 2.5641
237 1V35 NAI 2.5641
238 4E70 N7I 2.5641
239 3A27 SAM 2.57353
240 3VPH NAD 2.58065
241 3VPH OXM 2.58065
242 3CBG SAH 2.58621
243 2AQJ FAD 2.60223
244 2AQJ TRP 2.60223
245 5CG1 NAD BBN 2.62295
246 3OIG NAD 2.63158
247 1I1N SAH 2.65487
248 5K7U SAM 2.66667
249 5OVL NAP 2.66667
250 1ZEM NAD 2.67176
251 1NFQ NAI 2.69231
252 3OID NDP 2.71318
253 2NXE SAM 2.75591
254 4BLW AMP 2.76817
255 4BLW SAH 2.76817
256 6GFK SAH 2.78884
257 3KIF GDL 2.83019
258 5IL1 SAM 2.83019
259 4D42 NAP 2.83688
260 4D42 W0I 2.83688
261 2G5C NAD 2.84698
262 4Y30 49L 2.88462
263 4Y30 SAH 2.88462
264 3NDJ JHZ 2.88462
265 3NDJ SAH 2.88462
266 1I8T FAD 2.88462
267 6EL3 NAP 2.88462
268 1RSG FAD 2.88462
269 5TWB FAD 2.88462
270 1KYZ FER 2.88462
271 3ICT FAD 2.88462
272 1PN0 IPH 2.88462
273 4FWE FAD 2.88462
274 1PN0 FAD 2.88462
275 5I39 FAD 2.88462
276 1PS9 FAD 2.88462
277 3ICR FAD 2.88462
278 3ICS FAD 2.88462
279 1NAA ABL 2.88462
280 4RSL FAD 2.88462
281 4BJZ P3A 2.88462
282 4BJZ FAD 2.88462
283 1NAA 6FA 2.88462
284 1KYZ SAH 2.88462
285 1MO9 FAD 2.88462
286 3IHG FAD 2.88462
287 2NPX FAD 2.88462
288 4NTD FAD 2.88462
289 3FXU TSU 2.88462
290 1MO9 KPC 2.88462
291 3HB5 NAP 2.88462
292 1RYI FAD 2.88462
293 6F7L FAD 2.88462
294 3WGT QSC 2.88462
295 3WGT FAD 2.88462
296 4GLL NAD 2.88462
297 1OMO NAD 2.88462
298 1EK6 UPG 2.88462
299 1EK6 NAI 2.88462
300 2ZXI FAD 2.88462
301 4YRY NAD 2.89855
302 4YRY FAD 2.89855
303 2FZW NAD 2.94906
304 5BW4 SAM 2.99625
305 1SNY NAP 2.99625
306 4YAC NAI 3.0303
307 4KWI 1TJ 3.04183
308 4KWI NAP 3.04183
309 1E6W NAD 3.07692
310 1FK8 NAD 3.11284
311 4YAG NAI 3.11419
312 1WG8 SAM 3.15789
313 5YJI 8WO 3.16901
314 5YJI SAH 3.16901
315 5YJF SAH 3.16901
316 5YJF 8WO 3.16901
317 6ECU SAH 3.20513
318 6ECW SAH 3.20513
319 5FUB SAH 3.20513
320 1FP1 SAH 3.20513
321 2YX1 SFG 3.20513
322 4RPL 3UC 3.20513
323 4RPL FAD 3.20513
324 2CDU FAD 3.20513
325 1QO8 FAD 3.20513
326 3X0V FAD 3.20513
327 3S5W FAD 3.20513
328 5JJR SAH 3.20513
329 1YY5 FAD 3.20513
330 1Y8Q ATP 3.20513
331 3LKZ SFG 3.20513
332 1D4D FAD 3.20513
333 2QA1 FAD 3.20513
334 1UWK URO 3.20513
335 1UWK NAD 3.20513
336 3CGB FAD 3.20513
337 3S1S SAH 3.20513
338 3UOY NAP 3.20513
339 3UOY FAD 3.20513
340 5EB4 FAD 3.20513
341 6F97 FAD 3.20513
342 3FPZ AHZ 3.20513
343 2RGJ FAD 3.20513
344 5X68 FAD 3.20513
345 5M67 ADE 3.20513
346 5M67 NAD 3.20513
347 5M67 3D1 3.20513
348 2B4Q NAP 3.20513
349 5UAO FAD 3.20513
350 1KEW NAD 3.20513
351 1KEW TYD 3.20513
352 3ABI NAD 3.20513
353 2NVK FAD 3.20513
354 1E5Q NDP 3.20513
355 1J49 NAD 3.20513
356 5FWA J7C 3.20513
357 1SB8 UD2 3.20513
358 1SB8 NAD 3.20513
359 2CDU ADP 3.20513
360 3M6W SAM 3.20513
361 3RUV ANP 3.20513
362 1PL6 NAD 3.20513
363 1PL6 572 3.20513
364 3G89 SAM 3.21285
365 1GUZ NAD 3.22581
366 2P41 SAH 3.27869
367 1UAY ADN 3.30579
368 3I53 SAH 3.31325
369 3ELW GP3 3.33333
370 3ELW SAM 3.33333
371 2ZIF SAM 3.367
372 5MGZ SAH 3.38983
373 3GRU AMP 3.38983
374 4NEC SAH 3.40909
375 2BZG SAH 3.44828
376 5M58 SAH 3.47826
377 5WUW NAP 3.48432
378 3EYK EYK 3.48837
379 5YSS NAD 3.51562
380 5F8F SFG 3.52564
381 3X0D SAH 3.52564
382 3LST SAH 3.52564
383 5VN0 NAI 3.52564
384 5VN0 FAD 3.52564
385 5WGR FAD 3.52564
386 4OPC PGT 3.52564
387 4OPC FDA 3.52564
388 4JNA FAD 3.52564
389 2FR1 NDP 3.52564
390 6FDF SAH 3.52564
391 4YNU LGC 3.52564
392 6FP4 FAD 3.52564
393 6FP4 E1T 3.52564
394 1BXK NAD 3.52564
395 5KKA 6V0 3.52564
396 5Z21 NAI 3.52564
397 4O1M NAD 3.52564
398 5AHN IMP 3.52564
399 2PK3 A2R 3.52564
400 2I7C AAT 3.53357
401 3GCZ SAM 3.5461
402 2Q28 ADP 3.5461
403 4ZA2 NAD 3.55731
404 4Y9D NAI 3.60656
405 3EVF GTA 3.61011
406 3EVF SAH 3.61011
407 2RH4 EMO 3.61011
408 2WA2 SAM 3.62319
409 4QED NAP 3.62903
410 3EVG SAH 3.63636
411 2AG5 NAD 3.65854
412 1YC5 NCA 3.65854
413 4BUZ OCZ 3.65854
414 4BUZ NAD 3.65854
415 4BUZ OAD 3.65854
416 5N6C NAD 3.66667
417 3Q3C NAD 3.67893
418 3ML1 MGD 3.7037
419 2PX8 SAH 3.71747
420 5ULP KB1 3.73134
421 5CUQ NSC 3.74532
422 4NBT NAD 3.75
423 2HNK SAH 3.76569
424 1JQD SAH 3.76712
425 2AOT SAH 3.76712
426 1JQD HSM 3.76712
427 5UFN SAH 3.78151
428 1O97 FAD 3.78788
429 1O97 AMP 3.78788
430 1TL2 NDG 3.81356
431 1XCL SAH 3.82979
432 5KOK S9T 3.84615
433 5KOK SAH 3.84615
434 5KOK R9T 3.84615
435 4A6D SAM 3.84615
436 1ZGA SAH 3.84615
437 5HJM MTA 3.84615
438 2JB2 PHE 3.84615
439 2JB2 FAD 3.84615
440 5K4W NAI 3.84615
441 5K4W THR 3.84615
442 3CH6 311 3.84615
443 3CH6 NAP 3.84615
444 2DKH 3HB 3.84615
445 2DKH FAD 3.84615
446 4TXI FAD 3.84615
447 1Q1R FAD 3.84615
448 1LDN NAD 3.84615
449 2AE2 PTO 3.84615
450 2AE2 NAP 3.84615
451 4II2 ATP 3.84615
452 4EMI FAD 3.84615
453 5W7R 9Z7 3.84615
454 5W7R SAH 3.84615
455 1MUU NAD 3.84615
456 4KGD TDP 3.84615
457 1MV8 NAD 3.84615
458 4KGD FAD 3.84615
459 4EMI NAD 3.84615
460 1V8B NAD 3.84615
461 1EZ4 NAD 3.84615
462 4PLG OXM 3.84615
463 4PLG NAI 3.84615
464 2Q1W NAD 3.84615
465 5HJM HSL 3.84615
466 4LHD GLY 3.84615
467 5GWX SAR 3.87324
468 5GWX SAM 3.87324
469 3AFN NAP 3.87597
470 4OM8 NAD 3.8835
471 2WK1 SAH 3.90071
472 1E6E FAD 3.90625
473 3H2B SAH 3.94089
474 5JE8 NAD 3.97351
475 1W8D NAP 3.97351
476 1W73 NAP 3.97351
477 5N5D SAM 3.9823
478 1T26 NAI 4.03727
479 1T26 GBD 4.03727
480 5XNC MTA 4.04313
481 5DF1 58X 4.16667
482 5DF1 NAP 4.16667
483 4KRI SAH 4.16667
484 2IZ1 ATR 4.16667
485 5TTJ FAD 4.16667
486 1XHC FAD 4.16667
487 4TQG NDP 4.16667
488 4D5G FAD 4.16667
489 4D5G TPP 4.16667
490 3KO8 NAD 4.16667
491 1E7S NAP 4.16667
492 5JWC FAD 4.16667
493 3LCV SAM 4.27046
494 4NBW NAD 4.28016
495 5LOG SAH 4.29185
496 4K26 NDP 4.34783
497 4K26 SFF 4.34783
498 3SJ7 NDP 4.36508
499 5ZW3 SAH 4.44444
500 3QWI NAP 4.44444
501 3QWI CUE 4.44444
502 2EFJ SAH 4.48718
503 2EG5 SAH 4.48718
504 6D6Y SAH 4.48718
505 2YG3 FAD 4.48718
506 6BQ6 TER 4.48718
507 2C5A GDC 4.48718
508 2C5A NAD 4.48718
509 4REP FAD 4.48718
510 5GSN FAD 4.48718
511 5GSN MMZ 4.48718
512 4HA6 FAD 4.48718
513 5ZBC FAD 4.48718
514 4UP4 GAL NAG 4.48718
515 4EIP FAD 4.48718
516 2WET FAD 4.48718
517 4YKG NAD 4.48718
518 1D1T NAD 4.48718
519 6MVU K4V 4.48718
520 3EYA FAD 4.48718
521 1VL8 NAP 4.49438
522 1Q7B NAP 4.5082
523 1P1C SAH 4.52261
524 3PFG TLO 4.56274
525 3PFG SAM 4.56274
526 2YVJ FAD 4.58716
527 1YXM ADE 4.62046
528 4JK3 NAD 4.6332
529 1XKQ NDP 4.64286
530 3ICC NAP 4.70588
531 1JA9 NDP 4.74453
532 5JCA NDP 4.80769
533 5JCA FAD 4.80769
534 1PZG A3D 4.80769
535 4JDR FAD 4.80769
536 1KNR FAD 4.80769
537 1F8G NAD 4.80769
538 2A2C NG1 4.80769
539 2A2C ADP 4.80769
540 1DL5 SAH 4.80769
541 1X14 NAD 4.80769
542 1PGP 6PG 4.80769
543 2VYN NAD 4.80769
544 1QMG APX 4.80769
545 4J7U YTZ 4.86111
546 4J7U NAP 4.86111
547 5DM1 5D7 4.86891
548 5DM1 SAH 4.86891
549 1Z6Z NAP 4.96454
550 5L95 AMP 5
551 1OAA OAA 5.01931
552 6CI9 NAP 5.01931
553 3WV8 ATP 5.04587
554 1XSE NDP 5.08475
555 2IDV M7G 5.08475
556 2WSB NAD 5.11811
557 5WP5 SAH 5.12821
558 4AZW SAM 5.12821
559 4X60 3XV 5.12821
560 4X60 SFG 5.12821
561 4C4A SAH 5.12821
562 2V6G NAP 5.12821
563 5MLR GRQ 5.12821
564 5MLR NAP 5.12821
565 3UCL FAD 5.12821
566 3UCL NAP 5.12821
567 3UCL CYH 5.12821
568 3GF4 UPG 5.12821
569 3GF4 FAD 5.12821
570 1ELI PYC 5.12821
571 6ER9 FAD 5.12821
572 6ER9 NAP 5.12821
573 3LZW NAP 5.12821
574 3LZW FAD 5.12821
575 6GAS FAD 5.12821
576 1GTE FAD 5.12821
577 1COY AND 5.12821
578 1R6D NAD 5.12821
579 1R6D DAU 5.12821
580 1FEC FAD 5.12821
581 2A92 NAI 5.12821
582 1L7E NAI 5.12821
583 6BWL NAD 5.12821
584 3FUU ADN 5.16605
585 3U31 NAD 5.17241
586 5BSZ SAH 5.2
587 1IY8 NAD 5.24345
588 2GDZ NAD 5.24345
589 2VDV SAM 5.28455
590 1R18 SAH 5.28634
591 5GM1 SAH 5.38721
592 5WP4 SAH 5.44872
593 4D7E FAD 5.44872
594 2C7G ODP 5.44872
595 2C7G FAD 5.44872
596 1V59 NAD 5.44872
597 1GZ6 NAI 5.44872
598 1V59 FAD 5.44872
599 3GD4 NAD 5.44872
600 3GD4 FAD 5.44872
601 4U8P UDP 5.44872
602 4U8P FDA 5.44872
603 1EFV FAD 5.44872
604 1EFV AMP 5.44872
605 1ZBQ NAD 5.44872
606 4FZV SAM 5.44872
607 4BV6 FAD 5.44872
608 3OJO NAD 5.44872
609 4UCI SAM 5.44872
610 2R4J FAD 5.44872
611 2R4J 13P 5.44872
612 5EZ7 FAD 5.44872
613 1SOW NAD 5.44872
614 4X7Y SAH 5.47445
615 5O42 9JW 5.47445
616 5O42 NAD 5.47445
617 5O42 BGC 5.47445
618 1VL0 NAI 5.47945
619 3VYW SAM 5.51948
620 4NBU NAI 5.6
621 3CGD FAD 5.625
622 3CGD COA 5.625
623 3CGD NAD 5.625
624 4GUS FAD 5.64516
625 4GUT FAD 5.64516
626 4HSU FAD 5.64516
627 5Z2L NDP 5.71429
628 5MW4 5JU 5.76923
629 3QOX SAH 5.76923
630 3PT9 SAH 5.76923
631 5NMX NAP 5.76923
632 5NMX FAD 5.76923
633 2ZWA SAH 5.76923
634 5J5Z FAD 5.76923
635 2F5Z FAD 5.76923
636 5MBX FAD 5.76923
637 5MBX SP5 5.76923
638 3AXB FAD 5.76923
639 3AXB PRO 5.76923
640 6FHO FAD 5.76923
641 2JHP SAH 5.76923
642 5B4T 3HR 5.76923
643 5B4T NAD 5.76923
644 1X1T NAD 5.76923
645 5HXI 5HN 5.76923
646 5HXI FAD 5.76923
647 4DSG UDP 5.76923
648 4DSG FAD 5.76923
649 1RKX NAD 5.76923
650 3GMB FAD 5.76923
651 3LAD FAD 5.76923
652 4G5H NAP 5.76923
653 4G5H UD7 5.76923
654 4O0L NDP 5.81818
655 3OJF NDP 5.83658
656 3OJF IMJ 5.83658
657 1GEG NAD 5.85938
658 2OBF SAH 5.88235
659 2OBF F83 5.88235
660 3H4V DVP 5.90278
661 3H4V NAP 5.90278
662 3C3Y SAH 5.90717
663 1NM5 NAD 5.91133
664 4YUW 4JU 5.92105
665 4YUW S4M 5.92105
666 3FZG SAM 6
667 4RVG TYD 6.08974
668 4RVG SAM 6.08974
669 5NA1 FAD 6.08974
670 2Y6Q I7T 6.08974
671 2Y6Q FAD 6.08974
672 1F3L SAH 6.08974
673 3CTY FAD 6.08974
674 1ORR NAD 6.08974
675 4I54 1C1 6.08974
676 1RM0 NAI 6.08974
677 3LU1 NAD 6.08974
678 4L2I FAD 6.08974
679 3P2E SAH 6.22222
680 4PNE SAH 6.29139
681 1ZK4 NAP 6.3745
682 1ZK4 AC0 6.3745
683 5DNK SAH 6.41026
684 6ARJ BW4 6.41026
685 6ARJ SAH 6.41026
686 5DX8 SFG 6.41026
687 3AYI FAD 6.41026
688 3AYI HCI 6.41026
689 4EUE NAI 6.41026
690 5ZYN FAD 6.41026
691 5K0A FAD 6.41026
692 4USQ FAD 6.41026
693 4C3Y FAD 6.41026
694 4C3Y ANB 6.41026
695 4CNK FAD 6.41026
696 6B3A SAM 6.41026
697 5DXA SFG 6.41026
698 5DX1 SFG 6.41026
699 5DX0 SFG 6.41026
700 5DWQ SFG 6.41026
701 6DNT NAD 6.41026
702 2HJR APR 6.41026
703 2A14 SAH 6.46388
704 2VT3 ATP 6.51163
705 3O03 NAP 6.52921
706 2XVM SAH 6.53266
707 5OJI NAP 6.53846
708 5OJI ISN 6.53846
709 2PWY SAH 6.58915
710 5G3U FDA 6.73077
711 5G3U ITW 6.73077
712 5N0J FAD 6.73077
713 3Q9T FAY 6.73077
714 3AB1 FAD 6.73077
715 3QVP FAD 6.73077
716 1U1I NAD 6.73077
717 2VHW NAI 6.73077
718 3HVJ 705 6.78733
719 1JJV ATP 6.79612
720 5GT9 NAP 6.84411
721 4GKV NAD 6.84524
722 1SQL GUN 6.84932
723 2OOR NAD 6.89655
724 3WDM ADN 6.89655
725 1N2X SAM 6.97674
726 4RF2 NAP 6.98529
727 1NV8 SAM 7.04225
728 1NV8 MEQ 7.04225
729 4M73 SAH 7.05128
730 4M73 M72 7.05128
731 5F2K SAH 7.05128
732 5F2K OCA 7.05128
733 3P9C SAH 7.05128
734 4KIB SAH 7.05128
735 5JCM NAD 7.05128
736 5JCM FAD 7.05128
737 5JCM ISD 7.05128
738 3ZNN 4WL 7.05128
739 3ZNN FAD 7.05128
740 1G8K MGD 7.05128
741 2IV2 MGD 7.05128
742 1Z45 NAD 7.05128
743 3RFV 15L 7.11611
744 3RFV NAI 7.11611
745 3ZV6 NAD 7.11744
746 3ZV6 4HB 7.11744
747 6DUB SAH 7.20721
748 5T2U NAP 7.25806
749 4XUC 43G 7.33945
750 4XUC SAM 7.33945
751 6ECT SAM 7.37179
752 1RJD SAM 7.37179
753 3OND ADN 7.37179
754 3OND NAD 7.37179
755 3GDN FAD 7.37179
756 3GDN HBX 7.37179
757 3SSO SAH 7.37179
758 1LTH NAD 7.37179
759 5MB4 NDG 7.37179
760 2XYQ SAH 7.37705
761 5E1M SAH 7.46888
762 5E1M PRO PRO LYS ARG ILE ALA 7.46888
763 1U7T TDT 7.66284
764 1U7T NAD 7.66284
765 1GEE NAD 7.66284
766 4MO2 FDA 7.69231
767 4MO2 FAD 7.69231
768 2EJU SAH 7.69231
769 1BZL FAD 7.69231
770 4J4H 1J1 7.72201
771 4J4H NAI 7.72201
772 3MQ2 SAH 7.79817
773 3AY6 NAI 7.80669
774 3AY6 BGC 7.80669
775 5OVK NDP 7.8125
776 4FC7 NAP 7.94224
777 4FC7 COA 7.94224
778 5W7M SAH 8.01282
779 3VSE SAH 8.01282
780 4J1Q NDP 8.01282
781 2WPF WPF 8.01282
782 2WPF FAD 8.01282
783 1YBH FAD 8.01282
784 1KPG SAH 8.01394
785 1Q0S SAH 8.10811
786 4OBW SAM 8.17121
787 5ZZ6 NAD 8.17308
788 5ZZ6 ADP 8.17308
789 3MB5 SAM 8.23529
790 5FEU NAP 8.24742
791 5THY SAH 8.33333
792 5THZ SAH 8.33333
793 3TKA SAM 8.33333
794 2ZJ1 ARJ 8.33333
795 2ZJ1 NAD 8.33333
796 4MDH NAD 8.33333
797 1L1E SAH 8.36237
798 2CFC NAD 8.4
799 2DPM SAM 8.4507
800 3VZS NAP 8.56031
801 3T7S SAM 8.58209
802 2Z3Y F2N 8.65385
803 2Q7V FAD 8.65385
804 5WKC FAD 8.65385
805 1T9D FAD 8.65385
806 4YMH SAH 8.75
807 2ZFU SAH 8.83721
808 3TN7 NJP 8.94942
809 3TLJ SAH 8.97436
810 4M37 SAH 8.97436
811 1NW5 SAM 8.97436
812 4ONQ SFG 8.97436
813 1TPY SAH 9.05923
814 2GAG NAD 9.09091
815 3C6K SPD 9.18635
816 3C6K MTA 9.18635
817 3BXO SAM 9.20502
818 2O07 SPD 9.21053
819 2O07 MTA 9.21053
820 5OCM NAP 9.27835
821 5JAQ NAI 9.29487
822 5FFF NAP 9.33852
823 5FFF 5XC 9.33852
824 3LCC SAH 9.3617
825 3VC1 GST 9.61539
826 3VC1 SAH 9.61539
827 5J7X FAD 9.61539
828 3WMX NAD 9.61539
829 5Y1G NAD 9.61539
830 5Y1G AKB 9.61539
831 4QTU SAM 9.62963
832 3WLE NAD 9.67742
833 3FPF TNA 9.73154
834 3FPF MTA 9.73154
835 1IM8 SAI 9.83607
836 5BJX UDP 9.9359
837 5BJX NAD 9.9359
838 4POO SAM 10
839 5BRT CH9 10.2564
840 5BRT FAD 10.2564
841 3LXD FAD 10.2564
842 3QFA FAD 10.3448
843 2HMT NAI 10.4167
844 1L3I SAH 10.4167
845 2EWM NAD 10.4418
846 1SAY PYR 10.5263
847 4J56 FAD 10.5263
848 2GV8 FAD 10.5769
849 1VQW FAD 10.5769
850 2GVC FAD 10.5769
851 5FJN FAD 10.5769
852 5FJN BE2 10.5769
853 6H3O FAD 10.5769
854 1WY7 SAH 10.628
855 4TM3 FAD 10.8974
856 1X87 NAD 10.8974
857 5KOX FAD 10.8974
858 5KOX RFP 10.8974
859 4MIG G3F 10.8974
860 5DLY 5D7 10.9023
861 5DLY SAH 10.9023
862 5XLX SAH 10.9929
863 3RKR NAP 11.0687
864 1BC5 SAH 11.1524
865 5Y77 FAD 11.2179
866 4NTC FAD 11.2179
867 1I2B UPG 11.2179
868 1I2B USQ 11.2179
869 1I2B NAD 11.2179
870 3AD8 NAD 11.33
871 3AD8 FAD 11.33
872 3AD8 PYC 11.33
873 3RJ5 NAD 11.4173
874 6F5Z SAH 11.4754
875 1XDS SAM 11.4973
876 1OC2 TDX 11.5385
877 1OC2 NAD 11.5385
878 2Q46 NAP 11.8577
879 2YY7 NAD 11.859
880 3A4T SFG 12.0438
881 4FN4 NAD 12.2047
882 4YSX FAD 12.234
883 3DXY SAM 12.3853
884 4ONT SIA GAL BGC 12.4031
885 4MOP 2H5 12.5
886 1I9G SAM 12.5
887 3EGI ADP 12.6214
888 1VM6 NAD 12.7193
889 3Q87 SAM 12.9412
890 5GWT SIN 12.9496
891 5GWT NAD 12.9496
892 5MPT SAH 13.141
893 3A28 NAD 13.1783
894 2FK8 SAM 13.4615
895 1H9A NAP 13.4615
896 3A4V PYR 13.4615
897 3A4V NAD 13.4615
898 1JQ3 AAT 13.5135
899 3GEG NAD 13.7652
900 1QZZ SAM 13.7821
901 3RNM FAD 13.7931
902 3JWH SAH 13.8249
903 1HYH NAD 13.9159
904 1RP0 AHZ 14.0845
905 5ODQ FAD 14.1304
906 3O26 NDP 14.1479
907 5YEC ATP 14.2857
908 5MZI FYK 14.4231
909 5MZI FAD 14.4231
910 1JNR FAD 14.6667
911 1U2Z SAH 14.7436
912 1VKO NAD 15.0641
913 5ERG SAM 15.3846
914 5Z75 NAD 15.3846
915 3OU2 SAH 15.5963
916 2JJQ SAH 15.7051
917 5OJ7 AR6 15.7343
918 3QV1 NAD 15.8537
919 6GKV SAH 16.0256
920 1E3W NAD 16.092
921 3GDH SAH 16.1826
922 5W7K SAH 16.3462
923 1QAN SAH 16.3934
924 1XTP SAI 16.5354
925 3DMH SAM 16.6667
926 3DMH GMP 16.6667
927 3GU3 SAH 18.3099
928 1JG3 ADN 18.5897
929 2C31 TZD 18.5897
930 2C31 ADP 18.5897
931 1KPH SAH 19.1638
932 5JE0 SAH 19.4332
933 5JE0 AZ8 19.4332
934 2PXX SAH 19.5349
935 3ZLR X0B 19.6203
936 4R6W PC 20.155
937 4R6W SAH 20.155
938 5JGL SAM 20.7612
939 3OFK SAH 20.8333
940 5FA8 SAM 21.118
941 2FLI DX5 21.8182
942 4EMJ FAD 22.4299
943 4GQB 0XU 22.7273
944 4M38 SAH 23.8095
945 4IWN GEK 24.4541
946 5FA5 MTA 25
947 1VE3 SAM 25.5507
948 1EJ0 SAM 26.6667
949 5FTW SAH 29.6875
950 1NNU TCT 33.3333
951 1NNU NAD 33.3333
Pocket No.: 2; Query (leader) PDB : 5E9W; Ligand: SAH; Similar sites found with APoc: 41
This union binding pocket(no: 2) in the query (biounit: 5e9w.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 5EOW FAD 1.60256
2 1Q9I TEO 1.92308
3 1Q9I FAD 1.92308
4 1LLU NAD 1.92308
5 4LH7 1X8 2.24359
6 5BVA FAD 2.5641
7 3K7M FAD 2.5641
8 1GPE FAD 2.5641
9 2GMH FAD 2.5641
10 3E1T FAD 2.88462
11 2NPX NAD 2.88462
12 1RYI GOA 2.88462
13 5YB7 ORN 2.88462
14 5YB7 FAD 2.88462
15 5NUE NAD 3.20513
16 5HSA FAS 3.52564
17 4IV9 FAD 3.84615
18 1ZK7 FAD 4.48718
19 5GSN NAP 4.48718
20 4YKG FAD 4.48718
21 1COY FAD 5.12821
22 4J36 FAD 5.12821
23 4J36 1HR 5.12821
24 4A3X LAT 5.72687
25 1W6U NAP 5.96026
26 2CUL FAD 6.03448
27 5U5N NAD 6.09319
28 9LDB NAD 6.41026
29 2OOR TXP 6.89655
30 2IVF MGD 7.05128
31 1H82 FAD 7.69231
32 1H82 GZZ 7.69231
33 3GFB NAD 7.69231
34 5ME4 HP4 8.39416
35 3VZS CAA 8.56031
36 2GAG FOA 9.09091
37 2GAG FAD 9.09091
38 6A20 ADP 9.9359
39 3THR C2F 16.041
40 1MXH NAP 19.9275
41 1MXH DHF 19.9275
Pocket No.: 3; Query (leader) PDB : 5E9W; Ligand: SAH; Similar sites found with APoc: 81
This union binding pocket(no: 3) in the query (biounit: 5e9w.bio1) has 19 residues
No: Leader PDB Ligand