Receptor
PDB id Resolution Class Description Source Keywords
5E8J 2.35 Å EC: 2.1.1.56 CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE I WITH RAM HOMO SAPIENS MRNA CAPPING MRNA PROCESSING TRANSLATION
Ref.: MOLECULAR BASIS OF RNA GUANINE-7 METHYLTRANSFERASE ACTIVATION BY RAM. NUCLEIC ACIDS RES. V. 44 10423 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH B:501;
A:502;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
GOL A:501;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5E8J 2.35 Å EC: 2.1.1.56 CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE I WITH RAM HOMO SAPIENS MRNA CAPPING MRNA PROCESSING TRANSLATION
Ref.: MOLECULAR BASIS OF RNA GUANINE-7 METHYLTRANSFERASE ACTIVATION BY RAM. NUCLEIC ACIDS RES. V. 44 10423 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5E8J - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5E8J - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5E8J - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5E8J; Ligand: SAH; Similar sites found: 618
This union binding pocket(no: 1) in the query (biounit: 5e8j.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1H5Q NAP 0.009643 0.42118 None
2 2JAH NDP 0.002096 0.45329 0.809717
3 3G2O SAM 0.000002544 0.56897 1.00334
4 3L9W AMP 0.00009837 0.51751 1.28205
5 3L9W GSH 0.0004356 0.48324 1.28205
6 1FL2 FAD 0.02399 0.41016 1.29032
7 4Q9N NAI 0.00623 0.43038 1.34228
8 4RDI ATP 0.00352 0.42478 1.38889
9 3BMN NAP 0.009675 0.41986 1.38889
10 5JDI NAP 0.00978 0.41835 1.38889
11 3JQA NAP 0.01006 0.41644 1.38889
12 5K6A NAP 0.0118 0.4157 1.38889
13 3JQ9 NAP 0.01257 0.41436 1.38889
14 3BMO NAP 0.012 0.41406 1.38889
15 3BMQ NAP 0.0129 0.41382 1.38889
16 5JDC NAP 0.01224 0.41365 1.38889
17 3JQ7 NAP 0.01169 0.4133 1.38889
18 4CM8 NAP 0.01253 0.41316 1.38889
19 4CM9 NAP 0.01349 0.41288 1.38889
20 3JQ8 NAP 0.01422 0.41177 1.38889
21 3JQF NAP 0.01438 0.41154 1.38889
22 4CLR NAP 0.01419 0.41056 1.38889
23 4RDH AMP 0.003964 0.40987 1.38889
24 4CLO NAP 0.01479 0.40839 1.38889
25 4CME NAP 0.01776 0.40585 1.38889
26 4D79 ATP 0.009375 0.4052 1.44928
27 2PD4 NAD 0.01328 0.41897 1.45455
28 2PD4 DCN 0.0151 0.41621 1.45455
29 5THQ NDP 0.005856 0.4304 1.47059
30 4ITU NAI 0.0002972 0.49721 1.48699
31 4ITU 1HS 0.0005348 0.49572 1.48699
32 2VZ0 NAP 0.04525 0.41754 1.49254
33 2VZ0 D64 0.04525 0.41754 1.49254
34 2WD7 NAP 0.01175 0.41451 1.49254
35 5J60 FAD 0.002967 0.45645 1.60256
36 5EOW FAD 0.01773 0.4117 1.60256
37 3A25 SAM 0.0006694 0.45789 1.66113
38 3DUW SAH 0.0002115 0.48313 1.79372
39 1YQZ FAD 0.001707 0.48356 1.92308
40 1N4W FAD 0.001585 0.47311 1.92308
41 4X9M FAD 0.003373 0.45368 1.92308
42 2VVM FAD 0.004746 0.44629 1.92308
43 1LLU NAD 0.02389 0.4053 1.92308
44 1X7D ORN 0.03421 0.40055 1.92308
45 1E1M FAD 0.002459 0.47148 1.95652
46 1E1M NAP 0.002459 0.47148 1.95652
47 5ITV NAI 0.0007886 0.47382 1.96078
48 3D3W NAP 0.000124 0.51569 2.04918
49 1PR9 NAP 0.0001658 0.50954 2.04918
50 3H8V ATP 0.001992 0.43614 2.05479
51 1ZQ9 SAM 0.0001285 0.4908 2.10526
52 1AE1 NAP 0.005871 0.43409 2.1978
53 5T67 SAH 0.0004631 0.49661 2.24359
54 5T67 JHZ 0.0005925 0.49661 2.24359
55 2PT9 2MH 0.0005334 0.48619 2.24359
56 4ZCC FAD 0.001673 0.47839 2.24359
57 4ZCC NAI 0.001673 0.47839 2.24359
58 4HXY NDP 0.002156 0.4527 2.24359
59 2RGO FAD 0.00377 0.44811 2.24359
60 4M52 FAD 0.01685 0.42059 2.24359
61 2PT9 S4M 0.04626 0.40637 2.24359
62 4OSP NAP 0.006007 0.42854 2.28137
63 2DKN NAI 0.001227 0.46166 2.35294
64 5KVA SAM 0.000591 0.46656 2.51799
65 5X62 SAH 0.000001847 0.57239 2.5641
66 3TKY SAH 0.00001839 0.5321 2.5641
67 4PIO AVI 0.0001426 0.51274 2.5641
68 4PIO SAH 0.0001526 0.51274 2.5641
69 3NUG NAD 0.0003953 0.48831 2.5641
70 2BRY FAD 0.001447 0.46375 2.5641
71 1GPE FAD 0.008661 0.4378 2.5641
72 1GY8 NAD 0.01066 0.41906 2.5641
73 3A27 SAM 0.0002879 0.47471 2.57353
74 1I1N SAH 0.0001025 0.51166 2.65487
75 1ZEM NAD 0.0004499 0.47932 2.67176
76 3OID NDP 0.0006205 0.48165 2.71318
77 4BLW AMP 0.000134 0.5155 2.76817
78 4BLW SAH 0.000135 0.50419 2.76817
79 4D42 NAP 0.02546 0.41708 2.83688
80 4D42 W0I 0.02546 0.41708 2.83688
81 3NDJ JHZ 0.0006133 0.49685 2.88462
82 3NDJ SAH 0.0006133 0.49685 2.88462
83 5BR7 FLC 0.001988 0.48158 2.88462
84 5BR7 FAD 0.001988 0.48158 2.88462
85 1PN0 IPH 0.003292 0.46169 2.88462
86 1PN0 FAD 0.003165 0.46169 2.88462
87 3ICS FAD 0.002213 0.46065 2.88462
88 3ICR FAD 0.002411 0.4577 2.88462
89 1KYZ SAH 0.003614 0.45319 2.88462
90 3ICT FAD 0.003371 0.45051 2.88462
91 1KYZ FER 0.01132 0.44092 2.88462
92 2E5V FAD 0.01623 0.42229 2.88462
93 3WGT QSC 0.03101 0.41193 2.88462
94 3WGT FAD 0.02999 0.41193 2.88462
95 2FZW NAD 0.04156 0.40152 2.94906
96 4YAG NAI 0.005031 0.44697 3.11419
97 3LKZ SFG 0.000006306 0.55356 3.20513
98 2YX1 SFG 0.00001704 0.52256 3.20513
99 1FP1 SAH 0.000469 0.49278 3.20513
100 1D4D FAD 0.001733 0.47117 3.20513
101 5EB4 FAD 0.004201 0.44893 3.20513
102 1J49 NAD 0.01283 0.41267 3.20513
103 3G89 SAM 0.0000003963 0.59609 3.21285
104 3I53 SAH 0.0001758 0.48903 3.31325
105 3ELW SAM 0.00003151 0.55598 3.33333
106 3ELW GP3 0.00003339 0.55598 3.33333
107 5MGZ SAH 0.000004935 0.55848 3.38983
108 4NEC SAH 0.00000004479 0.64248 3.40909
109 5M58 SAH 0.000003815 0.56364 3.47826
110 1BXK NAD 0.006428 0.42712 3.52564
111 5KKA 6V0 0.01622 0.41136 3.52564
112 4O1M NAD 0.01453 0.41131 3.52564
113 2Q28 ADP 0.03863 0.40315 3.5461
114 4ZA2 NAD 0.00206 0.45087 3.55731
115 3EVF GTA 0.00007065 0.53597 3.61011
116 3EVF SAH 0.00005851 0.53597 3.61011
117 3EVG SAH 0.00001039 0.54093 3.63636
118 2PX8 SAH 0.00001632 0.53193 3.71747
119 5ULP KB1 0.000002005 0.58664 3.73134
120 4NBT NAD 0.008074 0.42236 3.75
121 2JB2 PHE 0.0004203 0.49871 3.84615
122 2JB2 FAD 0.0003982 0.49871 3.84615
123 3CH6 NAP 0.00306 0.47184 3.84615
124 3CH6 311 0.00306 0.47184 3.84615
125 2AE2 NAP 0.003302 0.45414 3.84615
126 2AE2 PTO 0.003302 0.45414 3.84615
127 1ZGA SAH 0.003297 0.44872 3.84615
128 1LDN NAD 0.01473 0.41224 3.84615
129 1V8B NAD 0.01954 0.4117 3.84615
130 1W8D NAP 0.007928 0.41705 3.97351
131 1XHC FAD 0.002884 0.45273 4.16667
132 4TQG NDP 0.002357 0.44806 4.16667
133 2IZ1 ATR 0.02489 0.40226 4.16667
134 5JWC FAD 0.02946 0.40183 4.16667
135 3LCV SAM 0.0000656 0.51323 4.27046
136 4NBW NAD 0.003394 0.43904 4.28016
137 5LOG SAH 0.0002207 0.48228 4.29185
138 4K26 NDP 0.002531 0.44932 4.34783
139 4K26 SFF 0.00487 0.44472 4.34783
140 3QWI NAP 0.001255 0.46543 4.44444
141 3QWI CUE 0.002056 0.46543 4.44444
142 2EG5 SAH 0.0000001587 0.61397 4.48718
143 1D1T NAD 0.01653 0.41097 4.48718
144 3EYA FAD 0.03203 0.40002 4.48718
145 5BW4 SAM 0.000008944 0.54114 4.54545
146 1G60 SAM 0.00003572 0.5188 4.54545
147 4CQM NAP 0.0002078 0.50026 4.54545
148 2NXE SAM 0.0001775 0.48436 4.54545
149 5HJM MTA 0.0000737 0.45763 4.54545
150 3NTD FAD 0.00309 0.45347 4.54545
151 3NTA FAD 0.003249 0.45239 4.54545
152 2B4Q NAP 0.002415 0.44896 4.54545
153 5IL1 SAM 0.003465 0.42509 4.54545
154 5CG1 NAD BBN 0.02458 0.42461 4.54545
155 5K7U SAM 0.004065 0.4219 4.54545
156 3NT6 FAD 0.01787 0.41562 4.54545
157 1QG6 TCL 0.0298 0.4089 4.54545
158 1QG6 NAD 0.0298 0.4089 4.54545
159 5HJM HSL 0.006587 0.40469 4.54545
160 3PFG TLO 0.00319 0.48404 4.56274
161 3PFG SAM 0.00319 0.48404 4.56274
162 1XKQ NDP 0.00238 0.45321 4.64286
163 1PZG A3D 0.002884 0.45385 4.80769
164 1X14 NAD 0.007358 0.4081 4.80769
165 1F8G NAD 0.01221 0.40506 4.80769
166 2UYQ SAM 0.00002221 0.459 4.83871
167 4J7U NAP 0.0006361 0.49195 4.86111
168 4J7U YTZ 0.0006361 0.49195 4.86111
169 1Z6Z NAP 0.0005155 0.48126 4.96454
170 5L95 AMP 0.0007468 0.45784 5
171 1XSE NDP 0.005135 0.44458 5.08475
172 2A92 NAI 0.002833 0.44826 5.12821
173 1L7E NAI 0.01205 0.40844 5.12821
174 1FEC FAD 0.04393 0.40262 5.12821
175 1IY8 NAD 0.0005339 0.482 5.24345
176 2VDV SAM 0.000001543 0.56952 5.28455
177 1R18 SAH 0.01769 0.42367 5.28634
178 5GM1 SAH 0.0000008382 0.60203 5.38721
179 4FZV SAM 0.00005018 0.51431 5.44872
180 4UCI SAM 0.0001722 0.48726 5.44872
181 4D7E FAD 0.001794 0.46287 5.44872
182 1V59 FAD 0.006666 0.44356 5.44872
183 1V59 NAD 0.0008247 0.44076 5.44872
184 1ZBQ NAD 0.006019 0.43236 5.44872
185 3OJO NAD 0.003578 0.43174 5.44872
186 2R4J FAD 0.02482 0.4191 5.44872
187 2R4J 13P 0.02482 0.4191 5.44872
188 1VL0 NAI 0.001427 0.45388 5.47945
189 5MW4 5JU 0.0001524 0.52063 5.76923
190 3QOX SAH 0.00007914 0.5094 5.76923
191 4DSG UDP 0.02465 0.42392 5.76923
192 4DSG FAD 0.02465 0.42392 5.76923
193 3LAD FAD 0.01843 0.41862 5.76923
194 3OJF IMJ 0.02281 0.41307 5.83658
195 3OJF NDP 0.02253 0.40762 5.83658
196 3H4V DVP 0.009877 0.43227 5.90278
197 3H4V NAP 0.03074 0.40652 5.90278
198 3C3Y SAH 0.0003154 0.47512 5.90717
199 4YUW 4JU 0.008141 0.46712 5.92105
200 4YUW S4M 0.007995 0.46712 5.92105
201 1W6U NAP 0.008692 0.41516 5.96026
202 3FZG SAM 0.0001978 0.47729 6
203 1F3L SAH 0.003569 0.45904 6.08974
204 4I54 1C1 0.02444 0.40034 6.08974
205 3P2E SAH 0.00002419 0.52902 6.22222
206 4PNE SAH 0.000000592 0.60912 6.29139
207 5DNK SAH 0.000002386 0.54144 6.41026
208 4CNK FAD 0.004202 0.44686 6.41026
209 1DMR PGD 0.04603 0.41303 6.41026
210 2A14 SAH 0.00004997 0.51663 6.46388
211 2XVM SAH 0.000000002679 0.69375 6.53266
212 5G3U FDA 0.0004279 0.49597 6.73077
213 5G3U ITW 0.0006065 0.49509 6.73077
214 3AB1 FAD 0.009138 0.43209 6.73077
215 1U1I NAD 0.02673 0.40289 6.73077
216 3EGV SAH 0.000186 0.45679 6.80272
217 2OBF F83 0.00002971 0.55851 6.81818
218 2OBF SAH 0.00002971 0.55851 6.81818
219 4AZW SAM 0.000007832 0.54922 6.81818
220 3H2B SAH 0.000009231 0.54592 6.81818
221 3GCZ SAM 0.00001251 0.53723 6.81818
222 3GWZ SAH 0.00002989 0.51158 6.81818
223 3GXO SAH 0.00007363 0.49674 6.81818
224 4C3Y FAD 0.002843 0.4584 6.81818
225 4J36 FAD 0.002098 0.45589 6.81818
226 4C3Y ANB 0.004129 0.45496 6.81818
227 4J36 1HR 0.003727 0.45446 6.81818
228 2Y6Q FAD 0.003179 0.44583 6.81818
229 2Y6Q I7T 0.006253 0.44583 6.81818
230 3GD4 FAD 0.01311 0.43694 6.81818
231 3GD4 NAD 0.01888 0.43694 6.81818
232 2JHP SAH 0.001813 0.4359 6.81818
233 4BV6 FAD 0.00935 0.43254 6.81818
234 2VT3 ATP 0.001643 0.42816 6.81818
235 2WET FAD 0.01633 0.42038 6.81818
236 2VHW NAI 0.02287 0.40831 6.81818
237 5GT9 NAP 0.0003058 0.4937 6.84411
238 4GKV NAD 0.02734 0.40241 6.84524
239 1N2X SAM 0.0003451 0.47941 6.97674
240 4M73 SAH 0.0000004708 0.63892 7.05128
241 4M73 M72 0.0000008303 0.62848 7.05128
242 4KIB SAH 0.000001197 0.58098 7.05128
243 5F2K OCA 0.00001524 0.55834 7.05128
244 5F2K SAH 0.00001524 0.55834 7.05128
245 3P9C SAH 0.003265 0.47438 7.05128
246 5T2U NAP 0.01853 0.40966 7.25806
247 2EJU SAH 0.0001245 0.49142 7.69231
248 3AY6 NAI 0.03181 0.40213 7.80669
249 4FC7 NAP 0.005934 0.44338 7.94224
250 4FC7 COA 0.005934 0.44338 7.94224
251 1KPG SAH 0.000006094 0.55927 8.01394
252 1Q0S SAH 0.0000735 0.51293 8.10811
253 4MDH NAD 0.01585 0.40694 8.33333
254 2CFC NAD 0.003525 0.43967 8.4
255 2Q7V FAD 0.001728 0.4692 8.65385
256 2ZFU SAH 0.000002977 0.57126 8.83721
257 4ONQ SFG 0.0002439 0.47802 8.97436
258 3TLJ SAH 0.00003102 0.44794 8.97436
259 5CUQ NSC 0.000003041 0.5923 9.09091
260 5F8F SFG 0.000001386 0.57494 9.09091
261 4AZT SAM 0.000003756 0.56121 9.09091
262 3HVJ 705 0.000116 0.5227 9.09091
263 2EFJ SAH 0.0001548 0.51907 9.09091
264 4YMH SAH 0.00005181 0.51367 9.09091
265 4E70 N7I 0.0001108 0.5134 9.09091
266 2V6G NAP 0.0002957 0.49441 9.09091
267 1RSG FAD 0.0007456 0.4885 9.09091
268 1FK8 NAD 0.000279 0.48745 9.09091
269 3LST SAH 0.0007183 0.48117 9.09091
270 1YY5 FAD 0.00134 0.47777 9.09091
271 2XVF FAD 0.001133 0.47388 9.09091
272 4FWE FAD 0.002208 0.46589 9.09091
273 3ABI NAD 0.001288 0.4621 9.09091
274 5JCA FAD 0.002775 0.45992 9.09091
275 5JCA NDP 0.005345 0.45924 9.09091
276 1MO9 FAD 0.01079 0.45205 9.09091
277 3IHG FAD 0.002258 0.44895 9.09091
278 4JNA FAD 0.005463 0.44518 9.09091
279 1MO9 KPC 0.01591 0.4435 9.09091
280 2X3N FAD 0.004798 0.44293 9.09091
281 4II2 ATP 0.002245 0.43766 9.09091
282 3MJE NDP 0.006192 0.42923 9.09091
283 4EIP FAD 0.01592 0.42522 9.09091
284 4EIP K2C 0.01592 0.42522 9.09091
285 2WYV NAD 0.007937 0.42402 9.09091
286 1MV8 NAD 0.009929 0.41533 9.09091
287 2Q2V NAD 0.01651 0.41213 9.09091
288 4GLL NAD 0.01808 0.40906 9.09091
289 3U31 NAD 0.01026 0.40862 9.09091
290 3C6K MTA 0.00056 0.48774 9.18635
291 3C6K SPD 0.00056 0.48774 9.18635
292 3BXO SAM 0.0000007855 0.58271 9.20502
293 2O07 SPD 0.0009642 0.46817 9.21053
294 2O07 MTA 0.0008342 0.46817 9.21053
295 5JAQ NAI 0.005094 0.44375 9.29487
296 3LCC SAH 0.00001839 0.52687 9.3617
297 3WLE NAD 0.008677 0.42915 9.67742
298 3FPF TNA 0.0005117 0.4933 9.73154
299 3FPF MTA 0.0005117 0.4933 9.73154
300 1IM8 SAI 0.004756 0.45097 9.83607
301 4POO SAM 0.0007576 0.46518 10
302 3LXD FAD 0.008156 0.42939 10.2564
303 1L3I SAH 0.002173 0.47661 10.4167
304 2HMT NAI 0.01874 0.44847 10.4167
305 4J56 FAD 0.01691 0.42223 10.5263
306 1SC6 NAD 0.02229 0.40461 10.5769
307 1WY7 SAH 0.00001246 0.54477 10.628
308 4MIG G3F 0.001069 0.48652 10.8974
309 4TM3 FAD 0.00283 0.47765 10.8974
310 5XLX SAH 0.0008843 0.45234 10.9929
311 1BC5 SAH 0.00009245 0.50624 11.1524
312 4NTC FAD 0.006765 0.43958 11.2179
313 2ZWA SAH 0.000003513 0.57043 11.3636
314 4XUC SAM 0.0000611 0.53215 11.3636
315 4XUC 43G 0.0000611 0.53215 11.3636
316 4C4A SAH 0.00003257 0.52064 11.3636
317 2P41 SAH 0.00003232 0.51831 11.3636
318 4Y2H 49K 0.0001933 0.51428 11.3636
319 4Y2H SAH 0.0002963 0.50508 11.3636
320 5JJR SAH 0.000008143 0.50289 11.3636
321 4AP3 FAD 0.0008172 0.50089 11.3636
322 4AP3 NAP 0.0008172 0.50089 11.3636
323 2WSB NAD 0.0005632 0.49238 11.3636
324 3BGD PM6 0.0003653 0.48529 11.3636
325 3BGD SAH 0.0002585 0.48529 11.3636
326 2GV8 FAD 0.0008888 0.47536 11.3636
327 1WG8 SAM 0.0004967 0.47382 11.3636
328 3CGD NAD 0.004351 0.47255 11.3636
329 3CGD COA 0.004351 0.47255 11.3636
330 3CGD FAD 0.004351 0.47255 11.3636
331 2GVC FAD 0.0009696 0.47221 11.3636
332 1VQW FAD 0.0009897 0.47178 11.3636
333 5BVA FAD 0.002006 0.46895 11.3636
334 3CGB FAD 0.001979 0.46193 11.3636
335 5BUK FAD 0.003221 0.45859 11.3636
336 5U8U FAD 0.006692 0.45612 11.3636
337 3NJ4 NAD 0.01623 0.45496 11.3636
338 3NJ4 AFX 0.01623 0.45496 11.3636
339 1EFV FAD 0.005761 0.45475 11.3636
340 1EFV AMP 0.00643 0.45228 11.3636
341 4NBU NAI 0.002592 0.44883 11.3636
342 3ZNN FAD 0.009945 0.44248 11.3636
343 3ZNN 4WL 0.009945 0.44248 11.3636
344 1KNR FAD 0.006323 0.44007 11.3636
345 4XQC NAD 0.007333 0.43968 11.3636
346 3GMB FAD 0.005979 0.43488 11.3636
347 4XQC 13D 0.01346 0.42725 11.3636
348 5L53 NAP 0.01031 0.40851 11.3636
349 1Y8Q ATP 0.0004762 0.40466 11.3636
350 5L4S 6KX 0.02936 0.40388 11.3636
351 5L4S NAP 0.02936 0.40388 11.3636
352 1OC2 TDX 0.03139 0.41585 11.5385
353 1OC2 NAD 0.03139 0.41585 11.5385
354 2Q46 NAP 0.002537 0.44653 11.8577
355 2YY7 NAD 0.0007612 0.47456 11.859
356 3A4T SFG 0.000004202 0.5668 12.0438
357 4FN4 NAD 0.00009752 0.51608 12.2047
358 3DXY SAM 0.00004075 0.49859 12.3853
359 1I9G SAM 0.00005126 0.51388 12.5
360 4MOP 2H5 0.001106 0.48843 12.5
361 3EGI ADP 0.0003745 0.48611 12.6214
362 5MPT SAH 0.000001032 0.58696 13.141
363 2FK8 SAM 0.000003905 0.56578 13.4615
364 3A4V NAD 0.003508 0.44854 13.4615
365 3A4V PYR 0.003508 0.44854 13.4615
366 1JQ3 AAT 0.0004642 0.48778 13.5135
367 3GRU AMP 0.00005327 0.51747 13.6364
368 2XYQ SAH 0.00004048 0.51382 13.6364
369 5N5D SAM 0.0001408 0.49129 13.6364
370 2BZG SAH 0.0003518 0.47072 13.6364
371 5KMS NAD 0.003176 0.46885 13.6364
372 2HNK SAH 0.0005581 0.46574 13.6364
373 5I39 FAD 0.001894 0.464 13.6364
374 1X87 NAD 0.001148 0.45491 13.6364
375 3KLJ FAD 0.002679 0.45071 13.6364
376 5JCM NAD 0.009103 0.44973 13.6364
377 5JCM FAD 0.009103 0.44973 13.6364
378 5JCM ISD 0.009598 0.44973 13.6364
379 2B9W FAD 0.01083 0.43986 13.6364
380 4EMI FAD 0.006262 0.43827 13.6364
381 4EMI NAD 0.01311 0.43827 13.6364
382 4JDR FAD 0.007321 0.43786 13.6364
383 5KMS FAD 0.00556 0.43757 13.6364
384 3RJ5 NAD 0.006693 0.43683 13.6364
385 4YSX FAD 0.007601 0.43608 13.6364
386 1EK6 NAI 0.02365 0.42089 13.6364
387 1G8K MGD 0.0356 0.41955 13.6364
388 1OMO NAD 0.008257 0.41621 13.6364
389 1UP7 NAD 0.009823 0.41412 13.6364
390 1GUZ NAD 0.01338 0.41179 13.6364
391 1EK6 UPG 0.03778 0.41164 13.6364
392 2IVF MGD 0.02646 0.40709 13.6364
393 5MZI FAD 0.01287 0.43803 14.4231
394 5MZI FYK 0.01325 0.43803 14.4231
395 1U2Z SAH 0.0001125 0.50223 14.7436
396 3OU2 SAH 0.0000004584 0.49062 15.5963
397 4KRG SAH 0.00000002742 0.65579 15.9091
398 1JQD SAH 0.000005663 0.57558 15.9091
399 3S1S SAH 0.000003172 0.57492 15.9091
400 2AOT SAH 0.000003347 0.55758 15.9091
401 2WA2 SAM 0.000009388 0.54019 15.9091
402 5GWX SAM 0.00004314 0.52775 15.9091
403 5GWX SAR 0.00004314 0.52775 15.9091
404 3X0D SAH 0.00003043 0.52201 15.9091
405 1DL5 SAH 0.0001084 0.50872 15.9091
406 5E72 SAM 0.00008147 0.50672 15.9091
407 1JQD HSM 0.0001229 0.50612 15.9091
408 2JJQ SAH 0.00005041 0.50137 15.9091
409 1XDS SAM 0.00007683 0.49313 15.9091
410 4RPL FAD 0.001605 0.48786 15.9091
411 2CDU FAD 0.0005707 0.48734 15.9091
412 4RPL 3UC 0.002111 0.48368 15.9091
413 4X7Y SAH 0.001102 0.47896 15.9091
414 3CTY FAD 0.001321 0.47807 15.9091
415 2Z3Y F2N 0.001735 0.47114 15.9091
416 5MBX SP5 0.003763 0.46278 15.9091
417 5MBX FAD 0.003763 0.46278 15.9091
418 4DMG SAM 0.0005398 0.46028 15.9091
419 2GAG NAD 0.002237 0.4593 15.9091
420 2PWY SAH 0.004093 0.45772 15.9091
421 1ZMD NAI 0.001279 0.45613 15.9091
422 1ZMD FAD 0.003477 0.45598 15.9091
423 3RNM FAD 0.003648 0.45493 15.9091
424 4USR FAD 0.002197 0.4549 15.9091
425 3GDN FAD 0.004277 0.45051 15.9091
426 3GDN HBX 0.005875 0.45051 15.9091
427 2F5Z FAD 0.004596 0.44989 15.9091
428 2RAB NAD 0.009969 0.44766 15.9091
429 2RAB FAD 0.005919 0.44528 15.9091
430 2GAG FOA 0.00653 0.44401 15.9091
431 2GAG FAD 0.00653 0.44401 15.9091
432 3AFN NAP 0.004653 0.43902 15.9091
433 1QZZ SAM 0.005254 0.43878 15.9091
434 5UAO FAD 0.008274 0.43226 15.9091
435 1KEW TYD 0.01443 0.42976 15.9091
436 4M37 SAH 0.01325 0.42673 15.9091
437 3QFA FAD 0.01407 0.42454 15.9091
438 1KEW NAD 0.02087 0.42226 15.9091
439 1YC5 NCA 0.009277 0.41812 15.9091
440 2CDU ADP 0.006278 0.41125 15.9091
441 4BUZ OCZ 0.01844 0.40748 15.9091
442 4BUZ NAD 0.01545 0.40748 15.9091
443 4BUZ OAD 0.01844 0.40748 15.9091
444 3GDH SAH 0.0000215 0.44943 16.1826
445 1QAN SAH 0.000009292 0.55072 16.3934
446 1XTP SAI 0.0000001578 0.62439 16.5354
447 5E1M SAH 0.00000003606 0.68985 18.1818
448 5E1M PRO PRO LYS ARG ILE ALA 0.00000003606 0.68985 18.1818
449 3JWH SAH 0.00000005347 0.62337 18.1818
450 4QTU SAM 0.000000003138 0.61907 18.1818
451 3T7S SAM 0.000000577 0.59855 18.1818
452 3VC1 GST 0.00001367 0.57273 18.1818
453 3VC1 SAH 0.00001367 0.57273 18.1818
454 1TPY SAH 0.000005941 0.55978 18.1818
455 5XVK SAH 0.000008563 0.5547 18.1818
456 1NV8 SAM 0.00005095 0.52793 18.1818
457 1NV8 MEQ 0.00005291 0.52537 18.1818
458 4DCM SAM 0.00001876 0.52365 18.1818
459 4N49 SAM 0.00003326 0.5226 18.1818
460 1LSS NAD 0.0001651 0.4903 18.1818
461 2YG3 FAD 0.0006759 0.48844 18.1818
462 4MO2 FDA 0.0006347 0.4863 18.1818
463 4MO2 FAD 0.0008885 0.48027 18.1818
464 3HDY FDA 0.002439 0.47697 18.1818
465 3HDY GDU 0.002516 0.47697 18.1818
466 1E6E FAD 0.001324 0.46936 18.1818
467 3HDY FAD 0.003513 0.46873 18.1818
468 1COY FAD 0.003087 0.45662 18.1818
469 4Z24 FAD 0.004565 0.44909 18.1818
470 4TXI FAD 0.002728 0.44906 18.1818
471 4J4H NAI 0.006813 0.44394 18.1818
472 4J4H 1J1 0.006813 0.44394 18.1818
473 3MB5 SAM 0.02561 0.44248 18.1818
474 3Q9T FAY 0.005994 0.43815 18.1818
475 1O97 FAD 0.01561 0.43164 18.1818
476 1O97 AMP 0.01561 0.43164 18.1818
477 4JK3 NAD 0.005094 0.42916 18.1818
478 1COY AND 0.02311 0.42345 18.1818
479 3QVP FAD 0.01603 0.42256 18.1818
480 3WV8 ATP 0.006084 0.41573 18.1818
481 3M6W SAM 0.004543 0.41557 18.1818
482 2OOR NAD 0.008576 0.41227 18.1818
483 1NM5 NAD 0.04487 0.40573 18.1818
484 2OOR TXP 0.01883 0.40333 18.1818
485 3GU3 SAH 0.000001464 0.55388 18.3099
486 1JG3 ADN 0.0001718 0.48501 18.5897
487 1KPH SAH 0.000006899 0.55676 19.1638
488 5JE0 AZ8 0.0000001034 0.66141 19.4332
489 5JE0 SAH 0.0000001034 0.66141 19.4332
490 2PXX SAH 0.0000002918 0.61518 19.5349
491 3ZLR X0B 0.01367 0.41939 19.6203
492 1MXH NAP 0.01457 0.42003 19.9275
493 1MXH DHF 0.02002 0.41315 19.9275
494 5DM1 5D7 0.000002474 0.60817 20.4545
495 5DM1 SAH 0.000002725 0.60458 20.4545
496 5THY SAH 0.000002655 0.57356 20.4545
497 5THZ SAH 0.00000464 0.56718 20.4545
498 1L1E SAH 0.000004349 0.56361 20.4545
499 3FRH SAH 0.000006746 0.55956 20.4545
500 3SSO SAH 0.0001914 0.5157 20.4545
501 2BD0 NAP 0.0002436 0.49997 20.4545
502 1NW5 SAM 0.0001529 0.48964 20.4545
503 3Q87 SAM 0.0002538 0.48567 20.4545
504 1I8T FAD 0.0008206 0.48313 20.4545
505 3AYI FAD 0.001494 0.48175 20.4545
506 3AYI HCI 0.001551 0.48175 20.4545
507 1QO8 FAD 0.001041 0.48125 20.4545
508 2ZIF SAM 0.0002381 0.48076 20.4545
509 2XVE FAD 0.002095 0.47968 20.4545
510 1ELI PYC 0.001635 0.46716 20.4545
511 4IV9 FAD 0.001958 0.46545 20.4545
512 4J1Q NDP 0.001065 0.4631 20.4545
513 3UOY FAD 0.006558 0.45783 20.4545
514 3UOY NAP 0.006558 0.45783 20.4545
515 4RSL FAD 0.002969 0.45211 20.4545
516 3VYW SAM 0.0001197 0.44781 20.4545
517 5EZ7 FAD 0.01545 0.41973 20.4545
518 5TUK FAD 0.009738 0.41973 20.4545
519 5ODQ FAD 0.02894 0.4087 20.4545
520 1O5I NAD 0.01108 0.40365 20.4545
521 3OFK SAH 0.000001887 0.49644 20.8333
522 5FA8 SAM 0.00008552 0.50782 21.118
523 4EMJ FAD 0.006405 0.4388 22.4299
524 1RJD SAM 0.000001013 0.59298 22.7273
525 3DMH GMP 0.00002193 0.54364 22.7273
526 3DMH SAM 0.00001172 0.54364 22.7273
527 5JGL SAM 0.00001225 0.53491 22.7273
528 2IID FAD 0.000462 0.50958 22.7273
529 2IID PHE 0.000462 0.50958 22.7273
530 1Q9I FAD 0.004298 0.46132 22.7273
531 1Q9I TEO 0.004298 0.46132 22.7273
532 5M67 ADE 0.008732 0.44012 22.7273
533 1GET FAD 0.01444 0.43919 22.7273
534 1GET NAP 0.0152 0.43919 22.7273
535 2CUL FAD 0.006447 0.43441 22.7273
536 5M67 3D1 0.01145 0.43412 22.7273
537 2YVJ FAD 0.007586 0.43309 22.7273
538 3FWN ATR 0.03007 0.40036 22.7273
539 4M38 SAH 0.00007562 0.50604 23.8095
540 4IWN GEK 0.0000008657 0.60137 24.4541
541 3FUU ADN 0.00001102 0.54238 25
542 3PT9 SAH 0.00001747 0.53056 25
543 5DX0 SFG 0.00004357 0.52562 25
544 5DX1 SFG 0.00004731 0.52393 25
545 5DX8 SFG 0.00004046 0.52307 25
546 5DWQ SFG 0.0000522 0.51993 25
547 3S5W FAD 0.0004411 0.48601 25
548 4EUE NAI 0.0005572 0.48254 25
549 1UWK NAD 0.002414 0.46584 25
550 1UWK URO 0.002414 0.46584 25
551 4GUS FAD 0.002394 0.46508 25
552 3AD8 NAD 0.00154 0.46369 25
553 4GUT FAD 0.002813 0.4634 25
554 4HSU FAD 0.002682 0.4626 25
555 5TTJ FAD 0.002884 0.45602 25
556 4OPC FDA 0.01268 0.45488 25
557 4OPC PGT 0.01434 0.45488 25
558 2AG5 NAD 0.002475 0.44844 25
559 5DXA SFG 0.00003642 0.44399 25
560 3AD8 PYC 0.01181 0.44379 25
561 3AD8 FAD 0.01181 0.44379 25
562 1U7T TDT 0.007065 0.43864 25
563 5J7X FAD 0.006286 0.43818 25
564 1ORR NAD 0.009786 0.42325 25
565 1U7T NAD 0.008432 0.42011 25
566 4OIV XX9 0.03028 0.40415 25
567 1VE3 SAM 0.000003136 0.5648 25.5507
568 1EJ0 SAM 0.000001171 0.58444 26.6667
569 5DLY SAH 0.00002285 0.55749 27.2727
570 5DLY 5D7 0.00002601 0.55749 27.2727
571 4LWP SAH 0.00001641 0.53182 27.2727
572 1G55 SAH 0.00008118 0.50233 27.2727
573 3VSE SAH 0.00004757 0.4944 27.2727
574 1P1C SAH 0.000252 0.48581 27.2727
575 1XCL SAH 0.0006419 0.47956 27.2727
576 2DPM SAM 0.0006287 0.4653 27.2727
577 1XG5 NAP 0.001423 0.46142 27.2727
578 4YRY FAD 0.003013 0.45813 27.2727
579 5FA5 MTA 0.00008971 0.49285 29.5455
580 4GQB 0XU 0.02034 0.4495 29.5455
581 3OND ADN 0.0065 0.44582 29.5455
582 3OND NAD 0.0065 0.44582 29.5455
583 3ML1 MGD 0.02073 0.43316 29.5455
584 1RKX NAD 0.00599 0.43121 29.5455
585 2G5C NAD 0.01584 0.40949 29.5455
586 5FTW SAH 0.000002244 0.57695 29.6875
587 4R6W PC 0.000004583 0.61022 31.8182
588 4R6W SAH 0.000001523 0.60686 31.8182
589 3UCL FAD 0.002137 0.48206 31.8182
590 3UCL CYH 0.002137 0.48206 31.8182
591 3UCL NAP 0.002333 0.48206 31.8182
592 1E5Q NDP 0.003371 0.4406 31.8182
593 3G5S FAD 0.007263 0.43403 31.8182
594 1P3D UMA 0.00546 0.42772 31.8182
595 1P31 EPU 0.004942 0.418 31.8182
596 3MQ2 SAH 0.00005687 0.5045 34.0909
597 4A6D SAM 0.00106 0.48187 34.0909
598 3E1T FAD 0.002159 0.46637 34.0909
599 1FP2 SAH 0.002035 0.45899 34.0909
600 4HA6 FAD 0.004275 0.45147 34.0909
601 3QV1 NAD 0.01162 0.41207 34.0909
602 1PS9 FAD 0.002385 0.46222 36.3636
603 5FJN BE2 0.004343 0.45296 36.3636
604 5FJN FAD 0.003821 0.45296 36.3636
605 1PS9 NAP 0.01721 0.40389 36.3636
606 5KOK SAH 0.0000001198 0.63302 38.6364
607 5KOK S9T 0.0000006025 0.63012 38.6364
608 5KOK R9T 0.000001248 0.61289 38.6364
609 1SQF SAM 0.0000191 0.52879 38.6364
610 4OBW SAM 0.000002234 0.52351 38.6364
611 1H82 FAD 0.002999 0.46863 38.6364
612 1H82 GZZ 0.003529 0.46863 38.6364
613 2IV2 MGD 0.01258 0.42118 38.6364
614 2RGJ FAD 0.002488 0.45228 40.9091
615 2GCE SFC 0.04272 0.40009 40.9091
616 3O7W SAM 0.00000008209 0.62686 43.1818
617 4KRI SAH 0.0000004198 0.61075 43.1818
618 5XVQ SAH 0.00000738 0.4714 47.7273
Pocket No.: 2; Query (leader) PDB : 5E8J; Ligand: SAH; Similar sites found: 10
This union binding pocket(no: 2) in the query (biounit: 5e8j.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1NFQ NAI 0.01779 0.4094 2.69231
2 2DFV NAD 0.02143 0.40063 11.3636
3 1VM6 NAD 0.01601 0.40401 12.7193
4 2WPF FAD 0.0361 0.42916 15.9091
5 3VPH OXM 0.03146 0.40041 15.9091
6 1NM5 NAP 0.04614 0.40441 18.1818
7 5A3B APR 0.01989 0.40088 20.4545
8 5M67 NAD 0.0101 0.43689 22.7273
9 2HQM FAD 0.005706 0.44423 31.8182
10 3O26 NDP 0.02115 0.40339 40.9091
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