Receptor
PDB id Resolution Class Description Source Keywords
5E1B 1.65 Å EC: 2.1.1.244 CRYSTAL STRUCTURE OF NRMT1 IN COMPLEX WITH SPKRIA PEPTIDE HOMO SAPIENS STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TR
Ref.: STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY THE H N-TERMINAL METHYLTRANSFERASE 1. GENES DEV. V. 29 2343 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
UNX A:318;
A:319;
A:312;
D:101;
A:326;
A:310;
B:316;
A:308;
B:319;
B:326;
B:323;
A:317;
A:311;
A:316;
B:308;
B:306;
B:313;
B:309;
A:309;
A:328;
A:321;
A:306;
A:307;
B:304;
A:320;
B:303;
B:310;
B:317;
A:327;
A:305;
A:324;
B:329;
A:315;
A:325;
A:314;
E:102;
E:101;
B:324;
B:312;
B:321;
A:313;
B:315;
B:311;
A:322;
B:314;
B:325;
B:307;
B:322;
B:320;
A:323;
B:327;
B:328;
B:305;
B:318;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data n/a n/a X n/a
GOL A:302;
A:304;
B:302;
A:303;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAH A:301;
B:301;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
SER PRO LYS ARG ILE ALA E:1;
D:1;
Valid;
Valid;
Atoms found MORE than expected: % Diff = 1.191;
Atoms found MORE than expected: % Diff = 1.17;
Kd = 0.8 uM
672.829 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5E1M 1.75 Å EC: 2.1.1.244 CRYSTAL STRUCTURE OF NTMT1 IN COMPLEX WITH PPKRIA PEPTIDE HOMO SAPIENS STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TR
Ref.: STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY THE H N-TERMINAL METHYLTRANSFERASE 1. GENES DEV. V. 29 2343 2015
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5E1O Kd = 0.3 uM ARG PRO LYS ARG ILE ALA n/a n/a
2 5CVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5E1M Kd = 2.8 nM PRO PRO LYS ARG ILE ALA n/a n/a
4 5E1B Kd = 0.8 uM SER PRO LYS ARG ILE ALA n/a n/a
5 5E2A - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 5E1D Kd = 0.1 uM TYR PRO LYS ARG ILE ALA n/a n/a
7 5CVD Kd = 0.39 uM DMG PRO ARG ARG ARG SER ARG LYS PRO n/a n/a
8 5E2B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5E1O Kd = 0.3 uM ARG PRO LYS ARG ILE ALA n/a n/a
2 5CVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5E1M Kd = 2.8 nM PRO PRO LYS ARG ILE ALA n/a n/a
4 5E1B Kd = 0.8 uM SER PRO LYS ARG ILE ALA n/a n/a
5 5E2A - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 5E1D Kd = 0.1 uM TYR PRO LYS ARG ILE ALA n/a n/a
7 5CVD Kd = 0.39 uM DMG PRO ARG ARG ARG SER ARG LYS PRO n/a n/a
8 5E2B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5E1O Kd = 0.3 uM ARG PRO LYS ARG ILE ALA n/a n/a
2 5CVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5E1M Kd = 2.8 nM PRO PRO LYS ARG ILE ALA n/a n/a
4 5E1B Kd = 0.8 uM SER PRO LYS ARG ILE ALA n/a n/a
5 5E2A - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 5E1D Kd = 0.1 uM TYR PRO LYS ARG ILE ALA n/a n/a
7 5CVD Kd = 0.39 uM DMG PRO ARG ARG ARG SER ARG LYS PRO n/a n/a
8 5E2B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 1XTP - SAI C14 H20 N6 O5 Se c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Ligand no: 2; Ligand: SER PRO LYS ARG ILE ALA; Similar ligands found: 174
No: Ligand ECFP6 Tc MDL keys Tc
1 SER PRO LYS ARG ILE ALA 1 1
2 ARG PRO LYS ARG ILE ALA 0.871287 0.920635
3 5JP PRO LYS ARG ILE ALA 0.830189 0.96875
4 TYR PRO LYS ARG ILE ALA 0.780702 0.867647
5 PRO PRO LYS ARG ILE ALA 0.723214 0.920635
6 3BY PRO LYS ARG ILE ALA 0.710526 0.852941
7 LYS PRO VAL LEU ARG THR ALA 0.647059 0.923077
8 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.571429 0.924242
9 DPN PRO DAR ILE NH2 0.555556 0.859375
10 LYS ALA PRO ARG ALY GLN LEU ALA THR LYS 0.554745 0.882353
11 ALA ARG MLZ SER ALA PRO ALA THR 0.539683 0.910448
12 THR LYS PRO ARG 0.537736 0.854839
13 ALA ASN SER ARG ALA PRO THR SER ILE ILE 0.537313 0.897059
14 THR PRO ARG ARG SER MLZ SER ALA 0.532258 0.869565
15 ASN ARG PRO ILE LEU SER LEU 0.53125 0.910448
16 GLU ARG THR ILE PRO ILE THR ARG GLU 0.53125 0.924242
17 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.523077 0.9375
18 SER HIS PRO ARG PRO ILE ARG VAL 0.521739 0.898551
19 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.521429 0.925373
20 ALA ASN SER ARG TRP PRO ALY SER ILE ILE 0.51773 0.774648
21 DPN PRO DAR DTH NH2 0.516667 0.861538
22 ALA MET ALA PRO ARG THR LEU LEU LEU 0.515152 0.857143
23 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.515152 0.924242
24 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.514493 0.847222
25 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.514085 0.865672
26 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.511111 0.893939
27 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.507692 0.838235
28 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.507463 0.84058
29 ALA ASN SER ARG ALY PRO THR SER ILE ILE 0.506944 0.898551
30 LEU PRO PHE ASP ARG THR THR ILE MET 0.506757 0.835616
31 CYS THR PRO SER ARG 0.504132 0.878788
32 SER ALA PRO ASP THR ARG PRO ALA 0.503817 0.882353
33 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.503448 0.847222
34 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.503401 0.84058
35 PRO PRO LYS LYS LYS ARG LYS VAL 0.5 0.84375
36 LEU PRO PHE GLU ARG ALA THR ILE MET 0.5 0.847222
37 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.5 0.884058
38 PRO SER ILE ASP ARG SER THR LYS PRO 0.5 0.925373
39 DTY ILE ARG LEU LPD 0.496183 0.826087
40 ARG PRO LYS PRO LEU VAL ASP PRO 0.495935 0.846154
41 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.493671 0.786667
42 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.489209 0.833333
43 SER ARG LYS ILE ASP ASN LEU ASP 0.488372 0.735294
44 GLU LEU PRO LEU VAL LYS ILE 0.488189 0.78125
45 SER SER GLY LYS VAL PRO LEU SER 0.484127 0.818182
46 DMG PRO ARG ARG ARG SER ARG LYS PRO 0.483607 0.882353
47 ALA ASN SER ARG LEU PRO THR SER ILE ILE 0.483333 0.818182
48 LEU PRO LYS MYK THR GLY GLY 0.482014 0.779412
49 ARG ARG ARG GLU ARG SER PRO THR ARG 0.481203 0.893939
50 SER SER GLY LYS VAL PRO LEU 0.479675 0.830769
51 DPN PRO DAR CYS NH2 0.479339 0.784615
52 ALA ALA ARG KCR SER ALA PRO ALA 0.478261 0.923077
53 LYS ARG ARG ARG HIS PRO SER GLY 0.477941 0.826087
54 LYS ARG ARG ARG HIS PRO SER 0.477612 0.835821
55 SER GLU LEU GLU ILE LYS ARG TYR 0.477612 0.71831
56 LEU PRO PRO GLU GLU ARG LEU ILE 0.477273 0.892308
57 HIS HIS ALA SER PRO ARG LYS 0.475524 0.865672
58 LEU PRO PRO VAL VAL ALA LYS GLU ILE 0.47482 0.757576
59 LEU PRO PHE ASP LYS THR THR ILE MET 0.472973 0.726027
60 LEU PRO PHE ASP LYS SER THR ILE MET 0.470588 0.753425
61 VAL MET ALA PRO ARG THR LEU PHE LEU 0.469799 0.833333
62 PRO LYS THR PRO LYS LYS ALA LYS LYS LEU 0.469697 0.784615
63 ILE ARG ALA ALA PRO PRO PRO LEU PHE 0.468531 0.852941
64 SER LEU SER ARG THR PRO ALA ASP GLY ARG 0.468531 0.909091
65 ARG PRO MET THR PHE LYS GLY ALA LEU 0.467949 0.821918
66 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.463855 0.824324
67 PRO ARG PRO ILE LEU LEU PRO TRP ARG NH2 0.463087 0.8
68 ARG PRO MET THR TYR LYS GLY ALA LEU 0.462025 0.789474
69 ILE SER PRO ARG THR LEU ASP ALA TRP 0.460606 0.849315
70 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.46 0.882353
71 GLY LEU LEU GLY SEP PRO VAL ARG ALA 0.457746 0.830986
72 ARG PRO GLN VAL PRO LEU ARG PRO MET 0.457746 0.814286
73 PRO ARG ARG PRO VAL ILE MET ARG ARG 0.457143 0.811594
74 DPN PRO ARG 0.456897 0.8125
75 SER ASP ILE LEU PHE PRO ALA ASP SER 0.456522 0.794118
76 ARG GLN ALA SEP ILE GLU LEU PRO SER MET 0.453988 0.815789
77 ACE GLN GLU ARG GLU VAL PRO CYS 0.451852 0.848485
78 ASP ARG VAL TYR ILE HIS PRO PHE 0.450617 0.810811
79 ALA ARG LYS ILE ASP ASN LEU ASP 0.449612 0.691176
80 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.44898 0.8
81 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.448718 0.849315
82 ARG ARG ALA SEP ALA PRO LEU PRO 0.446809 0.819444
83 SER SER TYR ARG ARG PRO VAL GLY ILE 0.446667 0.847222
84 SER PRO ARG LEU PRO LEU LEU GLU SER 0.446154 0.859375
85 ALA PRO ASP THR ARG PRO 0.446154 0.867647
86 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.44586 0.830986
87 LYS PRO LYS 0.443396 0.709677
88 LEU PRO PHE GLU ARG ALA THR VAL MET 0.443038 0.833333
89 ILE ARG LYS ILE LEU PHE LEU ASP GLY ILE 0.441379 0.731343
90 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.440789 0.722222
91 VAL PRO LEU ARG PRO MET THR TYR 0.44 0.8
92 SER ARG ASP HIS SER ARG THR PRO MET 0.43871 0.824324
93 SER GLU ILE GLU PHE ALA ARG LEU 0.437956 0.731343
94 PHE PRO THR LYS ASP VAL ALA LEU 0.4375 0.753623
95 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.436242 0.746479
96 ALA PRO ASP THR ARG PRO ALA PRO 0.43609 0.867647
97 GLN ALA SER TPO PRO ARG NIT 0.435065 0.710843
98 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.434483 0.828571
99 LYS GLY PRO PRO LEU PRO ARG PRO ARG VAL 0.434109 0.846154
100 ACE ARG THR PRO SEP LEU PRO THR PIP 0.433566 0.789474
101 SER LEU ILE PRO TPO PRO ASP LYS 0.433566 0.756757
102 ALA ILE ARG SER 0.432432 0.741935
103 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.432099 0.786667
104 ALA ASN SER ARG TRP PRO THR SER FAK ILE 0.431953 0.805195
105 PHE ASN ARG PRO VAL 0.431818 0.823529
106 PHE ASN PHE PRO GLN ILE THR 0.431655 0.746479
107 LEU ASP PRO ARG 0.430894 0.875
108 ARG PRO PRO LYS PRO ARG PRO ARG 0.430769 0.796875
109 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.430303 0.789474
110 ALA PRO PRO PRO ARG PRO PRO LYS PRO 0.429688 0.8
111 THR PRO THR ARG ASP VAL ALA THR SER PRO 0.42963 0.880597
112 ASP ARG VAL GLU LEU ASN ALA PRO ARG GLN 0.429577 0.865672
113 LYS VAL PRO ARG ASN GLN ASP TRP LEU 0.429448 0.794521
114 GLU LEU LYS ARG LYS MET ILE TYR MET 0.426573 0.648649
115 LEU SER SER PRO VAL THR LYS SER PHE 0.426573 0.794118
116 GLU PRO GLY GLY SER ARG 0.426357 0.90625
117 ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 0.425287 0.830986
118 SER PRO HIS ASN PRO ILE SER ASP VAL ASP 0.425197 0.808824
119 GLU LYS PRO SER SER SER 0.425 0.784615
120 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.422819 0.808219
121 ALA VAL PRO ILE ALA GLN 0.422764 0.78125
122 ASN ARG LEU ILE LEU THR GLY 0.421488 0.661538
123 GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.421429 0.753623
124 ARG VAL ALA SER PRO THR SER GLY VAL 0.421429 0.880597
125 ALA ASN SER ARG TRP PRO THR SER 2KK ILE 0.41954 0.794872
126 ALA PRO ALA LEU ARG VAL VAL LYS 0.418803 0.714286
127 SER SER ILE GLU PHE ALA ARG LEU 0.41844 0.720588
128 LEU PRO GLU THR GLY 0.418033 0.787879
129 ARG GLU ARG SER PRO THR ARG 0.418033 0.936508
130 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.417808 0.814286
131 ILE GLN GLN SER ILE GLU ARG ILE 0.417323 0.765625
132 SER VAL PRO ILE 0.415929 0.8125
133 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.415205 0.76
134 MET SER LEU PRO GLY ARG TRP LYS PRO LYS 0.414201 0.802632
135 GLY ARG PHE ALA ALA ALA ILE ALA LYS 0.413534 0.738462
136 HIS LYS ILE LEU HIS ARG LEU LEU GLN ASP 0.413333 0.753623
137 SER PRO LEU ASP SER LEU TRP TRP ILE 0.413333 0.753425
138 SER ALA GLU PRO VAL PRO LEU GLN LEU 0.413043 0.820895
139 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.412903 0.764706
140 LEU PRO PHE GLU LYS SER THR VAL MET 0.412903 0.739726
141 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.4125 0.8
142 ALA ASN SER ARG TRP PRO THR SER 2KP ILE 0.412429 0.794872
143 ALA GLY SER VAL GLU GLN TPO PRO LYS LYS 0.411765 0.743243
144 GLN ASN TYR PRO ILE VAL GLN 0.411348 0.722222
145 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.410596 0.73913
146 ALA ARG THR M3L GLN THR ALA ALA LYS ALA 0.410448 0.69863
147 GLU LEU PRO PRO VAL LYS ILE HIS CYS 0.409938 0.742857
148 GLY SER ASP PRO PHE LYS 0.409091 0.761194
149 PRO PRO PRO VAL PRO PRO ARG ARG ARG ARG 0.409091 0.830769
150 LYS PRO ILE VAL VAL LEU HIS GLY TYR 0.408805 0.726027
151 LYS LEU THR PRO LEU CYS VAL THR LEU 0.408759 0.791045
152 ARG ASP ARG ALA ALA LYS LEU 0.408696 0.714286
153 ARG THR PRO SEP LEU PRO THR 0.408451 0.833333
154 PHE PRO ARG 0.408333 0.78125
155 SER TYR SER PRO THR SEP PRO SER 0.408 0.722222
156 PRO PRO ARG PRO ILE TYR ASN ARG ASN 0.407895 0.819444
157 ASN TYR THR PRO GLY PRO GLY ILE ARG PHE 0.406061 0.835616
158 LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.406061 0.833333
159 LYS ILE LEU HIS ARG LEU LEU GLN ASP 0.405797 0.735294
160 LYS ARG LYS ARG LYS ARG LYS ARG LYS ARG 0.40566 0.666667
161 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.405063 0.819444
162 PHE LEU TRP GLY PRO ARG ALA LEU VAL 0.404908 0.802817
163 SER THR GLY GLY VAL M3L LYS PRO HIS ARG 0.404624 0.779221
164 TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA 0.403727 0.75
165 VAL ALA ARG SER 0.40367 0.714286
166 SER LEU LYS ILE ASP ASN LEU ASP 0.403101 0.632353
167 SER SER CYS PRO LEU SER LYS 0.403101 0.80303
168 VAL VAL ARG PRO GLY SER LEU ASP LEU PRO 0.402597 0.910448
169 GLU LEU ASN ARG LYS MET ILE TYR MET 0.401316 0.644737
170 ILE GLY PRO GLY ARG ALA PHE TYR ALA 0.401274 0.816901
171 VAL LYS PRO GLY 0.4 0.75
172 GLN ARG SER THR SEP THR PRO ASN VAL HIS 0.4 0.783784
173 ARG GLN PHE GLY PRO ASP PHE PRO THR ILE 0.4 0.859155
174 ARG SEP PRO VAL PHE SER 0.4 0.805556
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5E1M; Ligand: PRO PRO LYS ARG ILE ALA; Similar sites found: 243
This union binding pocket(no: 1) in the query (biounit: 5e1m.bio2) has 54 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5HUA FK5 0.02921 0.41166 None
2 1NBU PH2 0.03301 0.40164 None
3 5THY SAH 0.0000019 0.57153 1.65975
4 2UYQ SAM 0.0002697 0.52596 1.65975
5 5ULP KB1 0.00006132 0.49146 1.65975
6 5THZ SAH 0.000003836 0.46064 1.65975
7 5DLY SAH 0.00005997 0.44554 1.65975
8 5DLY 5D7 0.00006723 0.4358 1.65975
9 3P2E SAH 0.0000301 0.4204 1.77778
10 1L1E SAH 0.000004864 0.55353 2.07469
11 5HJM MTA 0.0001334 0.49474 2.07469
12 4RVG SAM 0.00008133 0.4256 2.07469
13 4RVG TYD 0.00008033 0.41841 2.07469
14 3MQ2 SAH 0.0000696 0.51786 2.29358
15 3N8K D1X 0.01027 0.43131 2.32558
16 4AZT SAM 0.0000008319 0.60068 2.48963
17 1F3L SAH 0.00002671 0.51592 2.48963
18 4ONQ SFG 0.0003558 0.48003 2.48963
19 4AZW SAM 0.000001367 0.455 2.48963
20 3M6W SAM 0.007032 0.42761 2.48963
21 4MUQ 2D8 0.02098 0.41161 2.48963
22 3FUU ADN 0.00004642 0.41104 2.48963
23 3LCV SAM 0.0001189 0.48357 2.90456
24 2W92 NGT 0.01954 0.42647 2.90456
25 1U2Z SAH 0.00007609 0.41936 2.90456
26 3AKK ADP 0.01531 0.41137 2.90456
27 4C4A SAH 0.00006853 0.40679 2.90456
28 1YFS ALA 0.03396 0.40469 2.90456
29 3AYI HCI 0.005954 0.40389 2.90456
30 3AYI FAD 0.005685 0.40389 2.90456
31 3OJO NAD 0.009241 0.40317 2.90456
32 4D86 ADP 0.01502 0.40236 2.90456
33 1PR9 NAP 0.002069 0.40091 2.90456
34 2A14 SAH 0.00002413 0.43042 3.04183
35 3DXY SAM 0.0001984 0.51293 3.21101
36 5JJR SAH 0.00008635 0.50823 3.3195
37 3EVG SAH 0.0000865 0.5082 3.3195
38 3GDH SAH 0.0001506 0.47518 3.3195
39 5CUQ NSC 0.0006959 0.41434 3.3195
40 1ZMD NAI 0.004259 0.41175 3.3195
41 1JQ3 AAT 0.001837 0.40786 3.3195
42 2HJR APR 0.009629 0.40241 3.3195
43 2Q0L NAP 0.02495 0.40114 3.3195
44 4YMH SAH 0.00003212 0.51738 3.33333
45 1NC2 DOE 0.03707 0.40783 3.61991
46 1NC4 DOF 0.04774 0.40134 3.61991
47 5FA8 SAM 0.0001498 0.4793 3.72671
48 3GCZ SAM 0.0001047 0.5044 3.73444
49 2ZWA SAH 0.0001104 0.48924 3.73444
50 5F2K OCA 0.000171 0.43607 3.73444
51 5F2K SAH 0.000171 0.43607 3.73444
52 5BW4 SAM 0.00000181 0.43529 3.73444
53 3FRH SAH 0.00004158 0.43039 3.73444
54 5MW4 5JU 0.0007875 0.42594 3.73444
55 1KYQ NAD 0.006605 0.42526 3.73444
56 2DPM SAM 0.003967 0.4219 3.73444
57 3QOX SAH 0.000122 0.41301 3.73444
58 2V3V MGD 0.01274 0.40133 3.73444
59 3EGI ADP 0.000182 0.53447 3.8835
60 1I1N SAH 0.001168 0.42868 3.9823
61 3PT9 SAH 0.00001661 0.54105 4.14938
62 4M38 SAH 0.00005761 0.50619 4.14938
63 2ZIF SAM 0.000232 0.48393 4.14938
64 1V59 NAD 0.0009717 0.47846 4.14938
65 4N49 SAM 0.0003859 0.46977 4.14938
66 1P77 ATR 0.01285 0.43504 4.14938
67 2Z3Y F2N 0.003216 0.40635 4.14938
68 1I9G SAM 0.0001215 0.40383 4.14938
69 5JE8 NAD 0.007637 0.40132 4.14938
70 2YIP YIO 0.04675 0.40305 4.34783
71 3O7W SAM 0.000002295 0.60176 4.56432
72 3VSE SAH 0.0000623 0.53805 4.56432
73 1Q0S SAH 0.00005952 0.42647 4.56432
74 3L9W GSH 0.004196 0.40412 4.56432
75 3L9W AMP 0.003371 0.40287 4.56432
76 3OFK SAH 0.000009322 0.5357 4.62963
77 1XCL SAH 0.0007663 0.42441 4.68085
78 5GM1 SAH 0.000005742 0.53948 4.97925
79 4D79 ATP 0.0027 0.43965 4.97925
80 4II2 ATP 0.002202 0.4364 4.97925
81 4BLW AMP 0.0005952 0.4231 4.97925
82 4BLW SAH 0.002171 0.42083 4.97925
83 1X14 NAD 0.01859 0.40411 4.97925
84 1FWV SGA MAG FUC 0.01388 0.43278 5.22388
85 3LLZ GAL NGA 0.0299 0.41035 5.26316
86 3GU3 SAH 0.000009704 0.58602 5.28169
87 3U31 NAD 0.004444 0.41976 5.39419
88 2HK9 ATR 0.02009 0.41629 5.39419
89 3PQB VGP 0.01431 0.40045 5.39419
90 1P1C SAH 0.00006823 0.42111 5.52764
91 2PXX SAH 0.0000006936 0.59741 5.5814
92 4M73 SAH 0.000001475 0.52025 5.80913
93 4M73 M72 0.000002294 0.5149 5.80913
94 2EJU SAH 0.0001304 0.50002 5.80913
95 1NV8 MEQ 0.000213 0.45797 5.80913
96 1NV8 SAM 0.0002689 0.45064 5.80913
97 1YXM ADE 0.007266 0.43378 5.80913
98 1SQF SAM 0.00001217 0.41917 5.80913
99 5FA5 MTA 0.00007447 0.52207 5.84615
100 4X60 SFG 0.0001355 0.42441 5.89147
101 4X60 3XV 0.0001405 0.42008 5.89147
102 3H2B SAH 0.000002786 0.57027 5.91133
103 3VYW SAM 0.0003016 0.47449 6.22407
104 1N2X SAM 0.0003028 0.46632 6.22407
105 1Y8Q ATP 0.0008231 0.44439 6.22407
106 1OBB NAD 0.005933 0.40855 6.22407
107 3QSB 743 0.04125 0.40008 6.22407
108 1L3I SAH 0.000217 0.46478 6.25
109 4QTU SAM 0.0000001317 0.62985 6.639
110 1KPG SAH 0.000005539 0.54548 6.639
111 4LWP SAH 0.00001697 0.54064 6.639
112 3A4T SFG 0.00001995 0.5214 6.639
113 2JHP SAH 0.001904 0.4506 6.639
114 5T67 JHZ 0.0003287 0.44543 6.639
115 3TLJ SAH 0.001321 0.43913 6.639
116 5T67 SAH 0.001095 0.42066 6.639
117 1EJ0 SAM 0.00001905 0.41361 6.66667
118 2VT3 ATP 0.007001 0.43556 6.97674
119 1KPH SAH 0.0000092 0.53595 7.05394
120 1X87 NAD 0.003233 0.4226 7.05394
121 3A27 SAM 0.0001032 0.50469 7.35294
122 2EG5 SAH 0.000001097 0.61742 7.46888
123 1IM8 SAI 0.000001248 0.57958 7.46888
124 2VDV SAM 0.0001383 0.51482 7.46888
125 5DX8 SFG 0.00003047 0.50869 7.46888
126 1QAN SAH 0.00003961 0.50851 7.46888
127 5DXA SFG 0.00003123 0.50823 7.46888
128 5E9W SAH 0.00000005092 0.44962 7.46888
129 5DX1 SFG 0.00003394 0.43602 7.46888
130 5DX0 SFG 0.00004093 0.43434 7.46888
131 5DWQ SFG 0.00004093 0.43006 7.46888
132 5L95 AMP 0.006609 0.41847 7.46888
133 2Z4T C5P 0.02472 0.41164 7.46888
134 2XVM SAH 0.00000005463 0.68104 7.53769
135 4IWN GEK 0.00000929 0.53061 7.86026
136 4YFB PAC 0.02538 0.40743 7.86517
137 2JJQ SAH 0.000009533 0.57156 7.88382
138 5X62 SAH 0.00003454 0.53211 7.88382
139 5FTW SAH 0.00002078 0.52572 7.88382
140 3LKZ SFG 0.00004271 0.51697 7.88382
141 3GRU AMP 0.00009138 0.48843 7.88382
142 3BGD SAH 0.000127 0.48235 7.88382
143 5GWX SAR 0.0001068 0.47355 7.88382
144 5GWX SAM 0.0001068 0.47355 7.88382
145 3VC1 SAH 0.00001536 0.45263 7.88382
146 3VC1 GST 0.00001536 0.45263 7.88382
147 3BGD PM6 0.0003013 0.452 7.88382
148 3S5W NAP 0.01968 0.40947 7.88382
149 4FN4 NAD 0.0027 0.40901 7.88382
150 3SSO SAH 0.002372 0.40826 7.88382
151 3S5W FAD 0.003801 0.4009 7.88382
152 5XVK SAH 0.000009433 0.53032 8.29876
153 1BC5 SAH 0.00008227 0.41784 8.29876
154 3ICT ADP 0.0287 0.40472 8.29876
155 4FZV SAM 0.00006857 0.50286 8.3682
156 4DMG SAM 0.001028 0.47723 8.71369
157 4E70 N7I 0.0007854 0.42958 9.54357
158 1ZEM NAD 0.005643 0.40409 9.54357
159 3C6K MTA 0.00146 0.41153 10.2362
160 3C6K SPD 0.00146 0.41153 10.2362
161 4KIB SAH 0.00002042 0.40854 10.3734
162 1JG3 ADN 0.0004488 0.4754 10.6383
163 3NDJ SAH 0.0002223 0.45286 10.7884
164 3NDJ JHZ 0.0002223 0.45286 10.7884
165 1RJD SAM 0.00008586 0.41244 10.7884
166 3UCL NAP 0.007512 0.40876 10.7884
167 1UWK NAD 0.004347 0.40329 10.7884
168 1UWK URO 0.004347 0.40329 10.7884
169 5LOG SAH 0.00009225 0.40529 11.1588
170 2AOT SAH 0.0000001829 0.6468 11.2033
171 3G89 SAM 0.000001184 0.6158 11.2033
172 1JQD SAH 0.000002249 0.52704 11.2033
173 1G55 SAH 0.00003686 0.51985 11.2033
174 1JQD HSM 0.00005376 0.48557 11.2033
175 5N53 8NB 0.01514 0.43382 11.2821
176 1WY7 SAH 0.0001148 0.48851 11.5942
177 4NEC SAH 0.0000004366 0.62874 11.6183
178 3FZG SAM 0.0003445 0.49028 12
179 4MUS 2D8 0.02766 0.40216 12.3223
180 4RDH AMP 0.001995 0.45381 12.4481
181 5K7U SAM 0.005456 0.42561 12.4481
182 5IL1 SAM 0.006236 0.42294 12.4481
183 1LSS NAD 0.0008676 0.45425 12.8571
184 1G60 SAM 0.00006051 0.40722 12.8631
185 1DL5 SAH 0.0003498 0.4528 14.1079
186 5TCI MLI 0.02158 0.42752 14.1079
187 3KRQ 3TR 0.01191 0.42532 14.5228
188 2PT9 2MH 0.0009081 0.4165 14.5228
189 5MGZ SAH 0.000009874 0.54556 14.8305
190 2I7C AAT 0.0007691 0.4191 14.841
191 3S1S SAH 0.00005486 0.49784 14.9378
192 5M58 SAH 0.000006793 0.4357 15.2174
193 2HNK SAH 0.0002434 0.4786 16.318
194 1TPY SAH 0.000007539 0.53969 17.0124
195 4Y2H SAH 0.00007702 0.46192 17.0124
196 4Y2H 49K 0.0001577 0.45048 17.0124
197 5JGL SAM 0.00002286 0.41066 17.0124
198 3BXO SAM 0.0000008953 0.43499 17.5732
199 5XVQ SAH 0.00001889 0.51751 17.6056
200 5DM1 SAH 0.00001711 0.45942 17.8423
201 5DM1 5D7 0.00001867 0.45403 17.8423
202 5E8J SAH 0.00000003606 0.68985 18.1818
203 3LCC SAH 0.000004398 0.4315 18.2979
204 3OU2 SAH 0.000006713 0.52667 19.7248
205 3PFG TLO 0.006344 0.42043 20.332
206 3PFG SAM 0.006344 0.42043 20.332
207 4F8L AES 0.04367 0.41304 20.6897
208 4KRG SAH 0.000000006078 0.70781 20.7469
209 3GWZ SAH 0.0005593 0.48519 20.7469
210 3GXO SAH 0.0009869 0.46843 20.7469
211 5F8F SFG 0.00002946 0.54132 21.1618
212 3JWH SAH 0.0000001897 0.44572 21.1982
213 3G2O SAM 0.000001009 0.59684 21.4047
214 1XDS SAM 0.0004667 0.48903 21.5768
215 1QZZ SAM 0.00339 0.44694 21.5768
216 3TKY SAH 0.00002188 0.42295 21.5768
217 3HVJ 705 0.0001443 0.43178 21.7195
218 5JE0 SAH 0.0000002095 0.56152 21.9917
219 5JE0 AZ8 0.0000002095 0.56152 21.9917
220 4PIO AVI 0.0002036 0.44278 22.4066
221 4PIO SAH 0.0002219 0.43852 22.4066
222 1Z3C SA8 0.00002367 0.45809 23.2365
223 4XUC 43G 0.0001502 0.44462 23.3945
224 4XUC SAM 0.0001502 0.44462 23.3945
225 2OBF SAH 0.00009147 0.42128 23.6515
226 2OBF F83 0.00009147 0.42128 23.6515
227 5KOK SAH 0.000001937 0.57736 24.0664
228 5KOK S9T 0.00002145 0.47503 24.0664
229 5KOK R9T 0.0001558 0.44703 24.0664
230 5MPT SAH 0.000000366 0.61704 24.4813
231 4OBW SAM 0.00001045 0.55029 25.3112
232 4KRI SAH 0.00001271 0.53514 25.3112
233 1KYZ SAH 0.00005028 0.52447 26.1411
234 3T7S SAM 0.0000002112 0.62798 26.556
235 4R6W SAH 0.00002177 0.4818 27.3859
236 1VE3 SAM 0.00004639 0.52061 27.7533
237 3Q87 SAM 0.0001086 0.41094 28
238 3DMH SAM 0.00004755 0.50987 28.2158
239 3DMH GMP 0.0001489 0.46413 28.2158
240 2NXE SAM 0.0001034 0.50464 29.8755
241 3EGV SAH 0.0004119 0.48172 29.8755
242 2FK8 SAM 0.000002125 0.56938 36.0996
243 4PNE SAH 0.000006748 0.45104 37.3444
Pocket No.: 2; Query (leader) PDB : 5E1M; Ligand: SAH; Similar sites found: 243
This union binding pocket(no: 2) in the query (biounit: 5e1m.bio2) has 54 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5HUA FK5 0.02921 0.41166 None
2 1NBU PH2 0.03301 0.40164 None
3 5THY SAH 0.0000019 0.57153 1.65975
4 2UYQ SAM 0.0002697 0.52596 1.65975
5 5ULP KB1 0.00006132 0.49146 1.65975
6 5THZ SAH 0.000003836 0.46064 1.65975
7 5DLY SAH 0.00005997 0.44554 1.65975
8 5DLY 5D7 0.00006723 0.4358 1.65975
9 3P2E SAH 0.0000301 0.4204 1.77778
10 1L1E SAH 0.000004864 0.55353 2.07469
11 5HJM MTA 0.0001334 0.49474 2.07469
12 4RVG SAM 0.00008133 0.4256 2.07469
13 4RVG TYD 0.00008033 0.41841 2.07469
14 3MQ2 SAH 0.0000696 0.51786 2.29358
15 3N8K D1X 0.01027 0.43131 2.32558
16 4AZT SAM 0.0000008319 0.60068 2.48963
17 1F3L SAH 0.00002671 0.51592 2.48963
18 4ONQ SFG 0.0003558 0.48003 2.48963
19 4AZW SAM 0.000001367 0.455 2.48963
20 3M6W SAM 0.007032 0.42761 2.48963
21 4MUQ 2D8 0.02098 0.41161 2.48963
22 3FUU ADN 0.00004642 0.41104 2.48963
23 3LCV SAM 0.0001189 0.48357 2.90456
24 2W92 NGT 0.01954 0.42647 2.90456
25 1U2Z SAH 0.00007609 0.41936 2.90456
26 3AKK ADP 0.01531 0.41137 2.90456
27 4C4A SAH 0.00006853 0.40679 2.90456
28 1YFS ALA 0.03396 0.40469 2.90456
29 3AYI HCI 0.005954 0.40389 2.90456
30 3AYI FAD 0.005685 0.40389 2.90456
31 3OJO NAD 0.009241 0.40317 2.90456
32 4D86 ADP 0.01502 0.40236 2.90456
33 1PR9 NAP 0.002069 0.40091 2.90456
34 2A14 SAH 0.00002413 0.43042 3.04183
35 3DXY SAM 0.0001984 0.51293 3.21101
36 5JJR SAH 0.00008635 0.50823 3.3195
37 3EVG SAH 0.0000865 0.5082 3.3195
38 3GDH SAH 0.0001506 0.47518 3.3195
39 5CUQ NSC 0.0006959 0.41434 3.3195
40 1ZMD NAI 0.004259 0.41175 3.3195
41 1JQ3 AAT 0.001837 0.40786 3.3195
42 2HJR APR 0.009629 0.40241 3.3195
43 2Q0L NAP 0.02495 0.40114 3.3195
44 4YMH SAH 0.00003212 0.51738 3.33333
45 1NC2 DOE 0.03707 0.40783 3.61991
46 1NC4 DOF 0.04774 0.40134 3.61991
47 5FA8 SAM 0.0001498 0.4793 3.72671
48 3GCZ SAM 0.0001047 0.5044 3.73444
49 2ZWA SAH 0.0001104 0.48924 3.73444
50 5F2K OCA 0.000171 0.43607 3.73444
51 5F2K SAH 0.000171 0.43607 3.73444
52 5BW4 SAM 0.00000181 0.43529 3.73444
53 3FRH SAH 0.00004158 0.43039 3.73444
54 5MW4 5JU 0.0007875 0.42594 3.73444
55 1KYQ NAD 0.006605 0.42526 3.73444
56 2DPM SAM 0.003967 0.4219 3.73444
57 3QOX SAH 0.000122 0.41301 3.73444
58 2V3V MGD 0.01274 0.40133 3.73444
59 3EGI ADP 0.000182 0.53447 3.8835
60 1I1N SAH 0.001168 0.42868 3.9823
61 3PT9 SAH 0.00001661 0.54105 4.14938
62 4M38 SAH 0.00005761 0.50619 4.14938
63 2ZIF SAM 0.000232 0.48393 4.14938
64 1V59 NAD 0.0009717 0.47846 4.14938
65 4N49 SAM 0.0003859 0.46977 4.14938
66 1P77 ATR 0.01285 0.43504 4.14938
67 2Z3Y F2N 0.003216 0.40635 4.14938
68 1I9G SAM 0.0001215 0.40383 4.14938
69 5JE8 NAD 0.007637 0.40132 4.14938
70 2YIP YIO 0.04675 0.40305 4.34783
71 3O7W SAM 0.000002295 0.60176 4.56432
72 3VSE SAH 0.0000623 0.53805 4.56432
73 1Q0S SAH 0.00005952 0.42647 4.56432
74 3L9W GSH 0.004196 0.40412 4.56432
75 3L9W AMP 0.003371 0.40287 4.56432
76 3OFK SAH 0.000009322 0.5357 4.62963
77 1XCL SAH 0.0007663 0.42441 4.68085
78 5GM1 SAH 0.000005742 0.53948 4.97925
79 4D79 ATP 0.0027 0.43965 4.97925
80 4II2 ATP 0.002202 0.4364 4.97925
81 4BLW AMP 0.0005952 0.4231 4.97925
82 4BLW SAH 0.002171 0.42083 4.97925
83 1X14 NAD 0.01859 0.40411 4.97925
84 1FWV SGA MAG FUC 0.01388 0.43278 5.22388
85 3LLZ GAL NGA 0.0299 0.41035 5.26316
86 3GU3 SAH 0.000009704 0.58602 5.28169
87 3U31 NAD 0.004444 0.41976 5.39419
88 2HK9 ATR 0.02009 0.41629 5.39419
89 3PQB VGP 0.01431 0.40045 5.39419
90 1P1C SAH 0.00006823 0.42111 5.52764
91 2PXX SAH 0.0000006936 0.59741 5.5814
92 4M73 SAH 0.000001475 0.52025 5.80913
93 4M73 M72 0.000002294 0.5149 5.80913
94 2EJU SAH 0.0001304 0.50002 5.80913
95 1NV8 MEQ 0.000213 0.45797 5.80913
96 1NV8 SAM 0.0002689 0.45064 5.80913
97 1YXM ADE 0.007266 0.43378 5.80913
98 1SQF SAM 0.00001217 0.41917 5.80913
99 5FA5 MTA 0.00007447 0.52207 5.84615
100 4X60 SFG 0.0001355 0.42441 5.89147
101 4X60 3XV 0.0001405 0.42008 5.89147
102 3H2B SAH 0.000002786 0.57027 5.91133
103 3VYW SAM 0.0003016 0.47449 6.22407
104 1N2X SAM 0.0003028 0.46632 6.22407
105 1Y8Q ATP 0.0008231 0.44439 6.22407
106 1OBB NAD 0.005933 0.40855 6.22407
107 3QSB 743 0.04125 0.40008 6.22407
108 1L3I SAH 0.000217 0.46478 6.25
109 4QTU SAM 0.0000001317 0.62985 6.639
110 1KPG SAH 0.000005539 0.54548 6.639
111 4LWP SAH 0.00001697 0.54064 6.639
112 3A4T SFG 0.00001995 0.5214 6.639
113 2JHP SAH 0.001904 0.4506 6.639
114 5T67 JHZ 0.0003287 0.44543 6.639
115 3TLJ SAH 0.001321 0.43913 6.639
116 5T67 SAH 0.001095 0.42066 6.639
117 1EJ0 SAM 0.00001905 0.41361 6.66667
118 2VT3 ATP 0.007001 0.43556 6.97674
119 1KPH SAH 0.0000092 0.53595 7.05394
120 1X87 NAD 0.003233 0.4226 7.05394
121 3A27 SAM 0.0001032 0.50469 7.35294
122 2EG5 SAH 0.000001097 0.61742 7.46888
123 1IM8 SAI 0.000001248 0.57958 7.46888
124 2VDV SAM 0.0001383 0.51482 7.46888
125 5DX8 SFG 0.00003047 0.50869 7.46888
126 1QAN SAH 0.00003961 0.50851 7.46888
127 5DXA SFG 0.00003123 0.50823 7.46888
128 5E9W SAH 0.00000005092 0.44962 7.46888
129 5DX1 SFG 0.00003394 0.43602 7.46888
130 5DX0 SFG 0.00004093 0.43434 7.46888
131 5DWQ SFG 0.00004093 0.43006 7.46888
132 5L95 AMP 0.006609 0.41847 7.46888
133 2Z4T C5P 0.02472 0.41164 7.46888
134 2XVM SAH 0.00000005463 0.68104 7.53769
135 4IWN GEK 0.00000929 0.53061 7.86026
136 4YFB PAC 0.02538 0.40743 7.86517
137 2JJQ SAH 0.000009533 0.57156 7.88382
138 5X62 SAH 0.00003454 0.53211 7.88382
139 5FTW SAH 0.00002078 0.52572 7.88382
140 3LKZ SFG 0.00004271 0.51697 7.88382
141 3GRU AMP 0.00009138 0.48843 7.88382
142 3BGD SAH 0.000127 0.48235 7.88382
143 5GWX SAR 0.0001068 0.47355 7.88382
144 5GWX SAM 0.0001068 0.47355 7.88382
145 3VC1 SAH 0.00001536 0.45263 7.88382
146 3VC1 GST 0.00001536 0.45263 7.88382
147 3BGD PM6 0.0003013 0.452 7.88382
148 3S5W NAP 0.01968 0.40947 7.88382
149 4FN4 NAD 0.0027 0.40901 7.88382
150 3SSO SAH 0.002372 0.40826 7.88382
151 3S5W FAD 0.003801 0.4009 7.88382
152 5XVK SAH 0.000009433 0.53032 8.29876
153 1BC5 SAH 0.00008227 0.41784 8.29876
154 3ICT ADP 0.0287 0.40472 8.29876
155 4FZV SAM 0.00006857 0.50286 8.3682
156 4DMG SAM 0.001028 0.47723 8.71369
157 4E70 N7I 0.0007854 0.42958 9.54357
158 1ZEM NAD 0.005643 0.40409 9.54357
159 3C6K MTA 0.00146 0.41153 10.2362
160 3C6K SPD 0.00146 0.41153 10.2362
161 4KIB SAH 0.00002042 0.40854 10.3734
162 1JG3 ADN 0.0004488 0.4754 10.6383
163 3NDJ SAH 0.0002223 0.45286 10.7884
164 3NDJ JHZ 0.0002223 0.45286 10.7884
165 1RJD SAM 0.00008586 0.41244 10.7884
166 3UCL NAP 0.007512 0.40876 10.7884
167 1UWK NAD 0.004347 0.40329 10.7884
168 1UWK URO 0.004347 0.40329 10.7884
169 5LOG SAH 0.00009225 0.40529 11.1588
170 2AOT SAH 0.0000001829 0.6468 11.2033
171 3G89 SAM 0.000001184 0.6158 11.2033
172 1JQD SAH 0.000002249 0.52704 11.2033
173 1G55 SAH 0.00003686 0.51985 11.2033
174 1JQD HSM 0.00005376 0.48557 11.2033
175 5N53 8NB 0.01514 0.43382 11.2821
176 1WY7 SAH 0.0001148 0.48851 11.5942
177 4NEC SAH 0.0000004366 0.62874 11.6183
178 3FZG SAM 0.0003445 0.49028 12
179 4MUS 2D8 0.02766 0.40216 12.3223
180 4RDH AMP 0.001995 0.45381 12.4481
181 5K7U SAM 0.005456 0.42561 12.4481
182 5IL1 SAM 0.006236 0.42294 12.4481
183 1LSS NAD 0.0008676 0.45425 12.8571
184 1G60 SAM 0.00006051 0.40722 12.8631
185 1DL5 SAH 0.0003498 0.4528 14.1079
186 5TCI MLI 0.02158 0.42752 14.1079
187 3KRQ 3TR 0.01191 0.42532 14.5228
188 2PT9 2MH 0.0009081 0.4165 14.5228
189 5MGZ SAH 0.000009874 0.54556 14.8305
190 2I7C AAT 0.0007691 0.4191 14.841
191 3S1S SAH 0.00005486 0.49784 14.9378
192 5M58 SAH 0.000006793 0.4357 15.2174
193 2HNK SAH 0.0002434 0.4786 16.318
194 1TPY SAH 0.000007539 0.53969 17.0124
195 4Y2H SAH 0.00007702 0.46192 17.0124
196 4Y2H 49K 0.0001577 0.45048 17.0124
197 5JGL SAM 0.00002286 0.41066 17.0124
198 3BXO SAM 0.0000008953 0.43499 17.5732
199 5XVQ SAH 0.00001889 0.51751 17.6056
200 5DM1 SAH 0.00001711 0.45942 17.8423
201 5DM1 5D7 0.00001867 0.45403 17.8423
202 5E8J SAH 0.00000003606 0.68985 18.1818
203 3LCC SAH 0.000004398 0.4315 18.2979
204 3OU2 SAH 0.000006713 0.52667 19.7248
205 3PFG TLO 0.006344 0.42043 20.332
206 3PFG SAM 0.006344 0.42043 20.332
207 4F8L AES 0.04367 0.41304 20.6897
208 4KRG SAH 0.000000006078 0.70781 20.7469
209 3GWZ SAH 0.0005593 0.48519 20.7469
210 3GXO SAH 0.0009869 0.46843 20.7469
211 5F8F SFG 0.00002946 0.54132 21.1618
212 3JWH SAH 0.0000001897 0.44572 21.1982
213 3G2O SAM 0.000001009 0.59684 21.4047
214 1XDS SAM 0.0004667 0.48903 21.5768
215 1QZZ SAM 0.00339 0.44694 21.5768
216 3TKY SAH 0.00002188 0.42295 21.5768
217 3HVJ 705 0.0001443 0.43178 21.7195
218 5JE0 SAH 0.0000002095 0.56152 21.9917
219 5JE0 AZ8 0.0000002095 0.56152 21.9917
220 4PIO AVI 0.0002036 0.44278 22.4066
221 4PIO SAH 0.0002219 0.43852 22.4066
222 1Z3C SA8 0.00002367 0.45809 23.2365
223 4XUC 43G 0.0001502 0.44462 23.3945
224 4XUC SAM 0.0001502 0.44462 23.3945
225 2OBF SAH 0.00009147 0.42128 23.6515
226 2OBF F83 0.00009147 0.42128 23.6515
227 5KOK SAH 0.000001937 0.57736 24.0664
228 5KOK S9T 0.00002145 0.47503 24.0664
229 5KOK R9T 0.0001558 0.44703 24.0664
230 5MPT SAH 0.000000366 0.61704 24.4813
231 4OBW SAM 0.00001045 0.55029 25.3112
232 4KRI SAH 0.00001271 0.53514 25.3112
233 1KYZ SAH 0.00005028 0.52447 26.1411
234 3T7S SAM 0.0000002112 0.62798 26.556
235 4R6W SAH 0.00002177 0.4818 27.3859
236 1VE3 SAM 0.00004639 0.52061 27.7533
237 3Q87 SAM 0.0001086 0.41094 28
238 3DMH SAM 0.00004755 0.50987 28.2158
239 3DMH GMP 0.0001489 0.46413 28.2158
240 2NXE SAM 0.0001034 0.50464 29.8755
241 3EGV SAH 0.0004119 0.48172 29.8755
242 2FK8 SAM 0.000002125 0.56938 36.0996
243 4PNE SAH 0.000006748 0.45104 37.3444
Pocket No.: 3; Query (leader) PDB : 5E1M; Ligand: SAH; Similar sites found: 149
This union binding pocket(no: 3) in the query (biounit: 5e1m.bio1) has 42 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2B4R NAD 0.003223 0.42533 1.65975
2 2B4R AES 0.00301 0.42529 1.65975
3 3QVP FAD 0.007203 0.42282 1.65975
4 3WV8 ATP 0.001894 0.41756 1.83486
5 4RPL 3UC 0.003495 0.45344 2.07469
6 4RPL FAD 0.003221 0.45315 2.07469
7 1NFQ NAI 0.01181 0.40186 2.07469
8 2PWY SAH 0.001526 0.45909 2.48963
9 1J0X NAD 0.009177 0.41802 2.48963
10 1UP7 NAD 0.007054 0.40215 2.48963
11 3CBG SAH 0.01452 0.40527 2.58621
12 4EMI FAD 0.01032 0.41098 2.68293
13 4EMI NAD 0.02269 0.41092 2.68293
14 2YY7 NAD 0.001649 0.43803 2.88462
15 3D3W NAP 0.0003905 0.46817 2.90456
16 5BUK FAD 0.004559 0.43279 2.90456
17 2WSB NAD 0.004649 0.42857 2.90456
18 5MBX SP5 0.01159 0.42135 2.90456
19 5MBX FAD 0.01159 0.42135 2.90456
20 1GET NAP 0.01926 0.41852 2.90456
21 1GET FAD 0.01822 0.41852 2.90456
22 5ITV NAI 0.004645 0.4184 2.90456
23 5EB4 FAD 0.009154 0.41529 2.90456
24 3NTD FAD 0.009966 0.41166 2.90456
25 4D42 NAP 0.01797 0.4095 2.90456
26 4D42 W0I 0.01797 0.4095 2.90456
27 3C3Y SAH 0.0003832 0.44513 2.95359
28 2VVM FAD 0.00314 0.43626 3.23232
29 2P41 SAH 0.0000274 0.48558 3.3195
30 1WG8 SAM 0.0002534 0.46344 3.3195
31 1ELI PYC 0.0007286 0.46255 3.3195
32 2BD0 NAP 0.0006823 0.45615 3.3195
33 3KLJ FAD 0.003614 0.42569 3.3195
34 2F5Z FAD 0.008872 0.41869 3.3195
35 1S7G APR 0.005767 0.41675 3.3195
36 2WPF WPF 0.03763 0.41434 3.3195
37 2WPF FAD 0.03692 0.41434 3.3195
38 3CGD NAD 0.02994 0.41343 3.3195
39 3CGD FAD 0.02994 0.41343 3.3195
40 3CGD COA 0.02994 0.41343 3.3195
41 1S7G NAD 0.009272 0.40527 3.3195
42 1M2K APR 0.008554 0.40291 3.3195
43 1JNR FAD 0.02896 0.41263 3.33333
44 5N5D SAM 0.00004399 0.48316 3.53982
45 2YX1 SFG 0.00001155 0.47897 3.73444
46 3CH6 311 0.003924 0.44772 3.73444
47 3CH6 NAP 0.003924 0.44772 3.73444
48 3K6V CIT 0.01393 0.43317 3.73444
49 1U1I NAD 0.009309 0.40872 3.73444
50 4MIG G3F 0.002966 0.44491 4.14938
51 3G5S FAD 0.004463 0.42624 4.14938
52 2HQM FAD 0.0124 0.41116 4.14938
53 2WA2 SAM 0.00001906 0.48589 4.56432
54 1PS9 FAD 0.003417 0.43561 4.56432
55 5M67 NAD 0.02035 0.40623 4.56432
56 4J4H NAI 0.01851 0.40493 4.56432
57 5M67 ADE 0.02245 0.40424 4.56432
58 4J4H 1J1 0.02205 0.4006 4.56432
59 1E6E FAD 0.001947 0.44117 4.6875
60 4GQB 0XU 0.02124 0.43344 4.70958
61 2BZG SAH 0.00001648 0.49446 4.74138
62 4GUT FAD 0.006643 0.42707 4.83871
63 4DCM SAM 0.00005059 0.46164 4.97925
64 1QO8 FAD 0.001199 0.45722 4.97925
65 4FC7 NAP 0.002131 0.4459 4.97925
66 4FC7 COA 0.002131 0.4459 4.97925
67 4OPC PGT 0.03064 0.42241 4.97925
68 4OPC FDA 0.027 0.42241 4.97925
69 1YQZ FAD 0.007821 0.43219 5.39419
70 4REP FAD 0.001944 0.44458 5.80913
71 5FJN BE2 0.003292 0.44017 5.80913
72 5FJN FAD 0.002851 0.44017 5.80913
73 3ZNN FAD 0.02424 0.40763 5.80913
74 3ZNN 4WL 0.02424 0.40763 5.80913
75 3RFV NAI 0.02828 0.40574 5.80913
76 2AG5 NAD 0.01004 0.40252 5.80913
77 3OID NDP 0.01366 0.40022 5.80913
78 4TQG NDP 0.001183 0.44144 6.22407
79 3E1T FAD 0.005607 0.42777 6.22407
80 3WGT QSC 0.02312 0.40365 6.22407
81 3WGT FAD 0.02226 0.40365 6.22407
82 2FAH MLA 0.0256 0.40336 6.22407
83 2PX8 SAH 0.00003254 0.48198 6.3197
84 2YVJ FAD 0.01536 0.40221 6.42202
85 2XYQ SAH 0.0001255 0.45924 6.55738
86 1ZQ9 SAM 0.00004774 0.47655 6.639
87 3A25 SAM 0.0001286 0.4582 6.639
88 2XVE FAD 0.009065 0.42983 6.639
89 1N4W FAD 0.005438 0.42838 6.639
90 4UCI SAM 0.0002097 0.45556 7.05394
91 4CNK FAD 0.005647 0.42273 7.05394
92 2EFJ SAH 0.007162 0.41911 7.05394
93 3GDN HBX 0.01616 0.41239 7.05394
94 3GDN FAD 0.012 0.41181 7.05394
95 3X0D SAH 0.00008947 0.47106 7.46888
96 4YNU FAD 0.01156 0.41432 7.46888
97 4YNU LGC 0.01363 0.41432 7.46888
98 3RIY NAD 0.006889 0.40964 7.46888
99 3DUW SAH 0.00009093 0.47077 7.62332
100 5E72 SAM 0.0002575 0.45927 7.88382
101 4J36 1HR 0.002276 0.44559 7.88382
102 4J36 FAD 0.001464 0.44295 7.88382
103 4TM3 FAD 0.007987 0.43689 7.88382
104 4POO SAM 0.001252 0.43402 7.88382
105 4C3Y FAD 0.004518 0.43012 7.88382
106 4C3Y ANB 0.00584 0.42964 7.88382
107 1XHL NDP 0.01217 0.42812 7.88382
108 1XSE NDP 0.006259 0.42275 7.88382
109 3CIF G3H 0.005043 0.42166 7.88382
110 3CIF NAD 0.003424 0.42148 7.88382
111 3GGO ENO 0.01949 0.4022 7.88382
112 3GGO NAI 0.01949 0.4022 7.88382
113 5KVA SAM 0.0002583 0.45922 8.27338
114 1IY8 NAD 0.002044 0.43396 8.29876
115 4J1Q NDP 0.003252 0.42102 8.29876
116 3ICS FAD 0.008508 0.41474 8.29876
117 3I53 SAH 0.0003785 0.45024 8.71369
118 5XLX SAH 0.0001124 0.46221 9.12863
119 5UAV TFB 0.01344 0.40274 9.12863
120 2E7Z MGD 0.01368 0.40239 9.12863
121 2Y6Q FAD 0.00819 0.40885 9.54357
122 2Y6Q I7T 0.01652 0.40885 9.54357
123 1SQL GUN 0.02863 0.40341 9.58904
124 4M52 FAD 0.006451 0.42407 9.95851
125 2O07 MTA 0.001018 0.44274 10.3734
126 2O07 SPD 0.001193 0.44274 10.3734
127 2B9W FAD 0.008899 0.42744 10.3734
128 3UCL FAD 0.002894 0.45603 10.7884
129 3UCL CYH 0.002894 0.45603 10.7884
130 2GNM MAN 0.02716 0.40534 10.7884
131 2PHU MAN MAN 0.03089 0.40289 10.7884
132 2V3B FAD 0.01115 0.40845 10.9091
133 2ZFU SAH 0.00009344 0.47556 11.1628
134 1ZGA SAH 0.000636 0.4615 11.2045
135 1NW5 SAM 0.0003471 0.44628 11.6183
136 2E5V FAD 0.003776 0.43559 12.0332
137 4BV6 FAD 0.008317 0.41812 12.0332
138 3H8V ATP 0.00218 0.41184 12.3288
139 2GVC FAD 0.002792 0.43062 12.4481
140 4RDI ATP 0.001012 0.42416 12.4481
141 1VQW FAD 0.002968 0.42945 12.8631
142 4HA6 FAD 0.006076 0.42618 13.6929
143 1R18 SAH 0.007809 0.42468 14.0969
144 2CDU FAD 0.002914 0.43338 14.1079
145 2PT9 S4M 0.01205 0.42056 14.5228
146 1GY8 NAD 0.007875 0.40838 15.3527
147 5DNK SAH 0.000002859 0.48406 16.5975
148 4A6D SAM 0.003028 0.43995 18.6722
149 1FP1 SAH 0.0008755 0.4578 27.8008
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