Receptor
PDB id Resolution Class Description Source Keywords
5E1B 1.65 Å EC: 2.1.1.244 CRYSTAL STRUCTURE OF NRMT1 IN COMPLEX WITH SPKRIA PEPTIDE HOMO SAPIENS STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TR
Ref.: STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY THE H N-TERMINAL METHYLTRANSFERASE 1. GENES DEV. V. 29 2343 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
UNX A:318;
A:319;
A:312;
D:101;
A:326;
A:310;
B:316;
A:308;
B:319;
B:326;
B:323;
A:317;
A:311;
A:316;
B:308;
B:306;
B:313;
B:309;
A:309;
A:328;
A:321;
A:306;
A:307;
B:304;
A:320;
B:303;
B:310;
B:317;
A:327;
A:305;
A:324;
B:329;
A:315;
A:325;
A:314;
E:102;
E:101;
B:324;
B:312;
B:321;
A:313;
B:315;
B:311;
A:322;
B:314;
B:325;
B:307;
B:322;
B:320;
A:323;
B:327;
B:328;
B:305;
B:318;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
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submit data
n/a X *
GOL A:302;
A:304;
B:302;
A:303;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAH A:301;
B:301;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
SER PRO LYS ARG ILE ALA E:1;
D:1;
Valid;
Valid;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
Kd = 0.8 uM
644.775 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5E1M 1.75 Å EC: 2.1.1.244 CRYSTAL STRUCTURE OF NTMT1 IN COMPLEX WITH PPKRIA PEPTIDE HOMO SAPIENS STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TR
Ref.: STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION BY THE H N-TERMINAL METHYLTRANSFERASE 1. GENES DEV. V. 29 2343 2015
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5E1O Kd = 0.3 uM ARG PRO LYS ARG ILE ALA n/a n/a
2 5CVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 6DTN Ki = 39 nM 6D6 PRO PRO LYS ARG ILE ALA NH2 n/a n/a
4 5E1M Kd = 2.8 nM PRO PRO LYS ARG ILE ALA n/a n/a
5 5E1B Kd = 0.8 uM SER PRO LYS ARG ILE ALA n/a n/a
6 5E2A - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5E1D Kd = 0.1 uM TYR PRO LYS ARG ILE ALA n/a n/a
8 5CVD Kd = 0.39 uM DMG PRO ARG ARG ARG SER ARG LYS PRO n/a n/a
9 5E2B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5E1O Kd = 0.3 uM ARG PRO LYS ARG ILE ALA n/a n/a
2 5CVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 6DTN Ki = 39 nM 6D6 PRO PRO LYS ARG ILE ALA NH2 n/a n/a
4 5E1M Kd = 2.8 nM PRO PRO LYS ARG ILE ALA n/a n/a
5 5E1B Kd = 0.8 uM SER PRO LYS ARG ILE ALA n/a n/a
6 5E2A - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5E1D Kd = 0.1 uM TYR PRO LYS ARG ILE ALA n/a n/a
8 5CVD Kd = 0.39 uM DMG PRO ARG ARG ARG SER ARG LYS PRO n/a n/a
9 5E2B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5E1O Kd = 0.3 uM ARG PRO LYS ARG ILE ALA n/a n/a
2 5CVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 6DTN Ki = 39 nM 6D6 PRO PRO LYS ARG ILE ALA NH2 n/a n/a
4 5E1M Kd = 2.8 nM PRO PRO LYS ARG ILE ALA n/a n/a
5 5E1B Kd = 0.8 uM SER PRO LYS ARG ILE ALA n/a n/a
6 5E2A - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5E1D Kd = 0.1 uM TYR PRO LYS ARG ILE ALA n/a n/a
8 5CVD Kd = 0.39 uM DMG PRO ARG ARG ARG SER ARG LYS PRO n/a n/a
9 5E2B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 1XTP - SAI C14 H20 N6 O5 Se c1nc(c2c(n....
11 6DUB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 231
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 XYA 0.573333 0.84058
20 ADN 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 OZP 0.518519 0.915493
44 AAT 0.515789 0.863014
45 LSS 0.515152 0.696629
46 KAA 0.514852 0.727273
47 J7C 0.511364 0.835616
48 KG4 0.51087 0.769231
49 A5A 0.510417 0.697674
50 SON 0.505495 0.805195
51 SRP 0.505155 0.805195
52 F0P 0.504505 0.915493
53 ADX 0.5 0.694118
54 5AL 0.5 0.779221
55 54H 0.5 0.681818
56 VMS 0.5 0.681818
57 KH3 0.5 0.866667
58 HY8 0.5 0.890411
59 AMO 0.5 0.805195
60 CA0 0.5 0.769231
61 N37 0.495495 0.9
62 HZ2 0.495413 0.890411
63 AHX 0.49505 0.753086
64 NVA LMS 0.49505 0.707865
65 TSB 0.494949 0.689655
66 53H 0.494949 0.674157
67 G5A 0.494737 0.712644
68 ABM 0.494382 0.74359
69 A2D 0.494382 0.74359
70 45A 0.494382 0.74359
71 ZAS 0.494253 0.808219
72 A6D 0.490196 0.759494
73 GEK 0.49 0.956522
74 8QN 0.49 0.779221
75 GAP 0.489583 0.769231
76 A3S 0.48913 0.884058
77 AN2 0.48913 0.734177
78 S4M 0.488889 0.831169
79 SRA 0.488636 0.746835
80 LAD 0.485437 0.810127
81 52H 0.484848 0.674157
82 AP2 0.483516 0.759494
83 A12 0.483516 0.759494
84 BA3 0.483516 0.74359
85 NEC 0.483146 0.788732
86 AOC 0.483146 0.842857
87 Y3J 0.481481 0.768116
88 VRT 0.479167 0.861111
89 50T 0.478723 0.734177
90 5AS 0.478261 0.655556
91 ADP 0.478261 0.74359
92 AP5 0.478261 0.74359
93 B4P 0.478261 0.74359
94 A3N 0.477778 0.830986
95 YSA 0.476636 0.712644
96 XAH 0.476636 0.768293
97 8LH 0.474747 0.759494
98 0XU 0.473684 0.897059
99 AT4 0.473118 0.7375
100 ADP MG 0.473118 0.763158
101 J4G 0.471154 0.818182
102 WAQ 0.471154 0.807692
103 NSS 0.470588 0.712644
104 8LE 0.469388 0.75
105 5AD 0.468354 0.791045
106 M33 0.468085 0.734177
107 AU1 0.468085 0.725
108 MAO 0.467391 0.797468
109 NB8 0.466667 0.775
110 A3G 0.466667 0.871429
111 TXA 0.466667 0.759494
112 N5O 0.466667 0.857143
113 3AM 0.465909 0.727273
114 8X1 0.465347 0.707865
115 8LQ 0.465347 0.782051
116 DAL AMP 0.465347 0.779221
117 ACP 0.463158 0.746835
118 ATP 0.463158 0.74359
119 A3T 0.463158 0.842857
120 HEJ 0.463158 0.74359
121 7D7 0.4625 0.785714
122 LEU LMS 0.461538 0.688889
123 9ZD 0.460784 0.740741
124 9ZA 0.460784 0.740741
125 APR 0.458333 0.766234
126 AQP 0.458333 0.74359
127 APC 0.458333 0.759494
128 AR6 0.458333 0.766234
129 PRX 0.458333 0.746835
130 5FA 0.458333 0.74359
131 F2R 0.457627 0.75
132 IOT 0.456897 0.761905
133 N5A 0.456522 0.855072
134 4AD 0.456311 0.794872
135 PAJ 0.456311 0.722892
136 WSA 0.45614 0.72093
137 HQG 0.455446 0.75641
138 FA5 0.453704 0.805195
139 8PZ 0.453704 0.712644
140 YAP 0.453704 0.794872
141 NVA 2AD 0.453608 0.849315
142 ATP MG 0.453608 0.763158
143 AD9 0.453608 0.725
144 SAP 0.453608 0.728395
145 AGS 0.453608 0.728395
146 ADP PO3 0.453608 0.763158
147 APC MG 0.453608 0.766234
148 ADV 0.453608 0.782051
149 RBY 0.453608 0.782051
150 PTJ 0.45283 0.731707
151 MHZ 0.452632 0.797468
152 00A 0.451923 0.740741
153 A3P 0.451613 0.74026
154 YLP 0.451327 0.771084
155 7MD 0.45045 0.768293
156 ALF ADP 0.45 0.707317
157 ADP ALF 0.45 0.707317
158 2VA 0.447917 0.819444
159 H1Q 0.447917 0.753247
160 OOB 0.446602 0.779221
161 ANP 0.444444 0.725
162 ACQ 0.444444 0.746835
163 TAT 0.444444 0.7375
164 T99 0.444444 0.7375
165 P5A 0.443396 0.719101
166 7D5 0.443182 0.708861
167 A1R 0.442308 0.7625
168 YLC 0.439655 0.790123
169 2AM 0.438202 0.717949
170 DLL 0.438095 0.779221
171 ARG AMP 0.4375 0.759036
172 A22 0.436893 0.734177
173 D3Y 0.436893 0.859155
174 ATF 0.435644 0.716049
175 MYR AMP 0.435185 0.746988
176 80F 0.434426 0.75
177 SO8 0.434343 0.808219
178 3UK 0.433962 0.769231
179 OAD 0.433962 0.769231
180 TAD 0.433628 0.765432
181 25A 0.432692 0.74359
182 ADP VO4 0.431373 0.734177
183 VO4 ADP 0.431373 0.734177
184 6YZ 0.431373 0.746835
185 9SN 0.431193 0.731707
186 TYM 0.431034 0.805195
187 PR8 0.429907 0.8
188 B5V 0.429907 0.759494
189 ADQ 0.428571 0.746835
190 YLB 0.42735 0.771084
191 FYA 0.425926 0.779221
192 9K8 0.425926 0.67033
193 1ZZ 0.425926 0.746988
194 3OD 0.425926 0.769231
195 PPS 0.425743 0.674419
196 B1U 0.423423 0.638298
197 MAP 0.423077 0.707317
198 4YB 0.421053 0.735632
199 A2P 0.421053 0.727273
200 ADP BMA 0.420561 0.746835
201 9X8 0.420561 0.75
202 TYR AMP 0.419643 0.794872
203 5SV 0.419048 0.731707
204 OZV 0.419048 0.74359
205 3NZ 0.416667 0.824324
206 YLA 0.416667 0.771084
207 8Q2 0.415254 0.688889
208 A3R 0.415094 0.7625
209 B5M 0.414414 0.75
210 B5Y 0.414414 0.75
211 LPA AMP 0.413793 0.768293
212 48N 0.413793 0.753086
213 AYB 0.413223 0.761905
214 ACK 0.413043 0.710526
215 QQY 0.413043 0.696203
216 BIS 0.412844 0.719512
217 JB6 0.412844 0.7625
218 PAP 0.41 0.730769
219 DQV 0.408696 0.75641
220 OVE 0.408602 0.7125
221 AMP DBH 0.40708 0.746835
222 4UV 0.40708 0.75
223 3AD 0.406977 0.852941
224 OMR 0.40678 0.738095
225 AF3 ADP 3PG 0.40678 0.743902
226 LAQ 0.405172 0.768293
227 A A 0.40367 0.74359
228 7C5 0.403509 0.789474
229 7MC 0.403361 0.75
230 KOY 0.401709 0.847222
231 4UU 0.4 0.75
Ligand no: 2; Ligand: SER PRO LYS ARG ILE ALA; Similar ligands found: 144
No: Ligand ECFP6 Tc MDL keys Tc
1 SER PRO LYS ARG ILE ALA 1 1
2 ARG PRO LYS ARG ILE ALA 0.711712 0.904762
3 TYR PRO LYS ARG ILE ALA 0.655738 0.852941
4 5JP PRO LYS ARG ILE ALA 0.650943 0.921875
5 LYS PRO VAL LEU ARG THR ALA 0.628099 0.907692
6 PRO PRO LYS ARG ILE ALA 0.598361 0.904762
7 3BY PRO LYS ARG ILE ALA 0.585366 0.838235
8 THR LYS PRO ARG 0.582524 0.868852
9 THR PRO ARG ARG SER MLZ SER ALA 0.554622 0.855072
10 LYS ALA PRO ARG ALY GLN LEU ALA THR LYS 0.54918 0.818182
11 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.539062 0.921875
12 ARG PRO LYS PRO LEU VAL ASP PRO 0.537815 0.830769
13 ARG GLN PRO ALA LYS ALA PRO LEU LEU 0.526316 0.835821
14 ARG LEU PRO ALA LYS ALA PRO LEU LEU 0.523077 0.848485
15 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.522727 0.814286
16 ALA ARG MLZ SER ALA PRO ALA THR 0.51145 0.869565
17 LYS ARG ARG ARG HIS PRO SER 0.51145 0.848485
18 HIS HIS ALA SER PRO ARG LYS 0.510791 0.878788
19 DPN PRO DAR CYS NH2 0.508475 0.784615
20 SER ALA PRO ASP THR ARG PRO ALA 0.507692 0.895522
21 ARG ARG ARG GLU ARG SER PRO THR ARG 0.503817 0.907692
22 CYS THR PRO SER ARG 0.5 0.892308
23 LYS ARG ARG ARG HIS PRO SER GLY 0.496296 0.838235
24 DPN PRO DAR DTH NH2 0.495868 0.861538
25 DMG PRO ARG ARG ARG SER ARG LYS PRO 0.495652 0.865672
26 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.48855 0.823529
27 ACE GLN GLU ARG GLU VAL PRO CYS 0.488189 0.861538
28 DPN PRO DAR ILE NH2 0.483607 0.84375
29 DPN PRO ARG 0.482456 0.825397
30 GLY LEU LEU GLY SEP PRO VAL ARG ALA 0.482014 0.816901
31 ALA ALA ARG KCR SER ALA PRO ALA 0.481752 0.9375
32 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.481203 0.909091
33 ALA MET ALA PRO ARG THR LEU LEU LEU 0.477612 0.842857
34 SER SER GLY LYS VAL PRO LEU 0.475806 0.830769
35 SER SER GLY LYS VAL PRO LEU SER 0.472441 0.818182
36 MET CYS PRO ARG MET THR ALA VAL MET 0.471831 0.842857
37 ALA PRO PRO PRO ARG PRO PRO LYS PRO 0.467742 0.8125
38 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.467153 0.878788
39 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.467153 0.833333
40 LYS PRO LYS 0.466019 0.770492
41 ARG PRO GLN VAL PRO LEU ARG PRO MET 0.464286 0.8
42 ASN ARG PRO ILE LEU SER LEU 0.462121 0.895522
43 GLU LYS PRO SER SER SER 0.461538 0.8125
44 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.459854 0.909091
45 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.459119 0.797297
46 PRO PRO LYS LYS LYS ARG LYS VAL 0.457944 0.677419
47 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.457143 0.8
48 SER PRO ARG LEU PRO LEU LEU GLU SER 0.456693 0.84375
49 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.455172 0.910448
50 SER HIS PRO ARG PRO ILE ARG VAL 0.454545 0.884058
51 ALA ASN SER ARG ALA PRO THR SER ILE ILE 0.453901 0.882353
52 LEU PRO LYS MYK THR GLY GLY 0.453901 0.779412
53 PRO SER ILE ASP ARG SER THR LYS PRO 0.452055 0.910448
54 1IP CYS PHE SER LYS PRO ARG 0.452055 0.855072
55 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.449664 0.826087
56 LEU PRO PRO GLU GLU ARG LEU ILE 0.447761 0.876923
57 THR PRO ARG VAL THR GLY GLY GLY ALA MET 0.447552 0.819444
58 ARG GLU ARG SER PRO THR ARG 0.445378 0.951613
59 ALA PRO ASP THR ARG PRO 0.445312 0.880597
60 GLU PRO GLY GLY SER ARG 0.444444 0.920635
61 SER LEU SER ARG THR PRO ALA ASP GLY ARG 0.444444 0.923077
62 ARG PRO MET THR PHE LYS GLY ALA LEU 0.44375 0.808219
63 LEU ASP PRO ARG 0.442623 0.875
64 ARG PRO MET THR TYR LYS GLY ALA LEU 0.440994 0.776316
65 LYS GLY PRO PRO LEU PRO ARG PRO ARG VAL 0.440945 0.830769
66 SER SER ARG LYS GLU TYR TYR ALA 0.44 0.657143
67 ALA ASN SER ARG ALY PRO THR SER ILE ILE 0.44 0.884058
68 LEU PRO PHE GLU ARG ALA THR VAL MET 0.43949 0.819444
69 GLU ARG THR ILE PRO ILE THR ARG GLU 0.439394 0.907692
70 PHE ASN ARG PRO VAL 0.439394 0.835821
71 SER SER TYR ARG ARG PRO VAL GLY ILE 0.439189 0.833333
72 LYS VAL PRO ARG ASN GLN ASP TRP LEU 0.439024 0.780822
73 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.439024 0.773333
74 ALA PHE ARG ILE PRO LEU THR ARG 0.438356 0.882353
75 ALA ARG LYS LEU ASP 0.4375 0.703125
76 PRO PRO PRO VAL PRO PRO ARG ARG ARG ARG 0.4375 0.84375
77 LYS ARG LYS 0.436893 0.688525
78 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.436364 0.776316
79 ALA LEU PRO HIS ALA ILE LEU ARG LEU 0.436242 0.850746
80 ALA ARG THR M3L GLN THR ALA ALA LYS ALA 0.435115 0.684932
81 GLN ALA SER TPO PRO ARG NIT 0.434211 0.719512
82 MET SER LEU PRO GLY ARG TRP LYS PRO LYS 0.432749 0.789474
83 ARG ARG ALA SEP ALA PRO LEU PRO 0.432624 0.805556
84 ILE ARG ALA ALA PRO PRO PRO LEU PHE 0.431507 0.838235
85 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.431373 0.895522
86 ARG VAL ALA SER PRO THR SER GLY VAL 0.430657 0.893939
87 ASP ARG VAL GLU LEU ASN ALA PRO ARG GLN 0.429577 0.850746
88 SER ARG ASP HIS SER ARG THR PRO MET 0.429487 0.810811
89 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.429412 0.77027
90 VAL PRO LEU ARG PRO MET THR TYR 0.426667 0.786667
91 GLU LEU PRO LEU VAL LYS ILE 0.425373 0.796875
92 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.425287 0.810811
93 VAL PRO PRO PRO ARG PRO PRO PRO PRO GLU 0.425197 0.830769
94 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.425 0.816901
95 LEU PRO PHE GLU ARG ALA THR ILE MET 0.425 0.833333
96 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.425 0.855072
97 VAL MET ALA PRO ARG THR LEU PHE LEU 0.424837 0.819444
98 ALA GLY SER VAL GLU GLN TPO PRO LYS LYS 0.423841 0.753425
99 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.423841 0.833333
100 SER THR GLY GLY VAL M3L LYS PRO HIS ARG 0.423529 0.766234
101 LYS ARG LYS ARG LYS ARG LYS ARG LYS ARG 0.422018 0.645161
102 ARG PRO PRO ILE PHE ILE ARG ARG LEU 0.421769 0.850746
103 ARG ASP ARG ALA ALA LYS LEU 0.421053 0.698413
104 ALA PRO ASP THR ARG PRO ALA PRO 0.421053 0.880597
105 VAL ALA ARG SER 0.420561 0.725806
106 ARG ARG ALA ALA 0.419048 0.677419
107 GLY GLN VAL PRO PHE SER LYS GLU GLU CYS 0.418919 0.782609
108 PRO VAL LYS ARG ARG LEU ASP LEU GLU 0.417266 0.784615
109 ALA ASN SER ARG TRP PRO ALY SER ILE ILE 0.416667 0.824324
110 VAL ARG SER ARG ARG ABA LEU ARG LEU 0.416667 0.738462
111 LEU PRO PHE ASP ARG THR THR ILE MET 0.416667 0.821918
112 ALA ASN SER ARG LEU PRO THR SER ILE ILE 0.416058 0.909091
113 VAL LYS PRO GLY 0.415929 0.793651
114 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.415584 0.869565
115 LEU PRO PRO VAL VAL ALA LYS GLU ILE 0.415493 0.772727
116 GLY SER ASP PRO PHE LYS 0.415385 0.787879
117 ALA PRO ALA LEU ARG VAL VAL LYS 0.415254 0.698413
118 LYS LYS LYS ALA 0.414141 0.606557
119 SER SER CYS PRO LEU SER LYS 0.414062 0.80303
120 LEU SER SER PRO VAL THR LYS SER PHE 0.413793 0.779412
121 PRO ARG ARG PRO VAL ILE MET ARG ARG 0.412587 0.797101
122 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.412162 0.794521
123 PHE PRO THR LYS ASP VAL ALA LEU 0.412162 0.768116
124 ILE LYS ARG SER LYS LYS ASN SER LEU ALA 0.410714 0.741935
125 LEU PRO PHE GLU LYS SER THR VAL MET 0.409091 0.739726
126 SER ALA GLU PRO VAL PRO LEU GLN LEU 0.408759 0.80597
127 PRO SER ARG VAL 0.408696 0.84127
128 VAL LEU ARG ASP ASP LEU LEU GLU ALA 0.408333 0.651515
129 PHE PRO ARG 0.408333 0.793651
130 ALA ARG THR LYS GLN THR ALA ARG LYS 0.40625 0.707692
131 ARG SEP PRO VAL PHE SER 0.405405 0.816901
132 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.405063 0.830986
133 LYS ARG ARG LYS SEP VAL 0.403361 0.695652
134 TYR PRO SER LYS PRO ASP ASN PRO GLY GLU 0.403101 0.73913
135 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.402597 0.764706
136 LYS ALA ALA ARG M3L SER ALA 0.401575 0.704225
137 SER ARG LYS ILE ASP ASN LEU ASP 0.40146 0.720588
138 THR PRO THR ARG ASP VAL ALA THR SER PRO 0.401408 0.895522
139 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.4 0.810811
140 ARG THR PRO SEP LEU PRO THR 0.4 0.819444
141 ILE SER PRO ARG THR LEU ASP ALA TRP 0.4 0.835616
142 SER LEU ILE PRO TPO PRO ASP LYS 0.4 0.756757
143 ALA ARG ALA ALA ALA ALA ALA ALA ALA 0.4 0.688525
144 GLY PRO ARG PRO 0.4 0.796875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5E1M; Ligand: PRO PRO LYS ARG ILE ALA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5e1m.bio2) has 54 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5E1M; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5e1m.bio2) has 54 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5E1M; Ligand: SAH; Similar sites found with APoc: 3
This union binding pocket(no: 3) in the query (biounit: 5e1m.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 4KRG SAH 20.7469
2 5WP5 SAH 21.9917
3 5WP5 SAH 21.9917
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