Receptor
PDB id Resolution Class Description Source Keywords
5DX8 1.94 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED PABP1 (R455) HOMO SAPIENS PROTEIN-SUBSTRATE TERNARY COMPLEX TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO TERNARY COMPLEX FORMATION CARM1 WITH VARIOUS SUBSTRATES. ACS CHEM.BIOL. V. 11 763 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SFG D:501;
B:501;
A:501;
C:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DX8 1.94 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED PABP1 (R455) HOMO SAPIENS PROTEIN-SUBSTRATE TERNARY COMPLEX TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO TERNARY COMPLEX FORMATION CARM1 WITH VARIOUS SUBSTRATES. ACS CHEM.BIOL. V. 11 763 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5DX8 - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5DX8 - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5DX8 - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DX8; Ligand: SFG; Similar sites found: 376
This union binding pocket(no: 1) in the query (biounit: 5dx8.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3JUT GTQ 0.03299 0.41248 None
2 4PIO SAH 0.0001905 0.47487 1.23839
3 4PIO AVI 0.0001997 0.47258 1.23839
4 4ONQ SFG 0.00003073 0.51075 1.43266
5 3LCC SAH 0.000007631 0.48478 1.70213
6 1GPE FAD 0.0002504 0.48306 1.7192
7 3L9W AMP 0.000713 0.44641 1.7192
8 3L9W GSH 0.001139 0.43499 1.7192
9 1FEC FAD 0.006299 0.42217 1.7192
10 2VVM FAD 0.0105 0.40699 1.7192
11 1Z82 G3P 0.02955 0.40315 1.79104
12 1ZEM NAD 0.003838 0.41015 1.9084
13 2EG5 SAH 0.00004142 0.52259 2.00573
14 4UCI SAM 0.0004348 0.43035 2.00573
15 1I8T FAD 0.003936 0.42451 2.00573
16 3CGD FAD 0.0181 0.41892 2.00573
17 3CGD COA 0.0181 0.41892 2.00573
18 3CGD NAD 0.0181 0.41892 2.00573
19 2JB2 PHE 0.005883 0.41795 2.00573
20 2JB2 FAD 0.005578 0.41795 2.00573
21 2Q7V FAD 0.004139 0.42559 2.15385
22 3VYW SAM 0.0001418 0.47217 2.27273
23 4D7E FAD 0.0008285 0.45027 2.29226
24 1SQF SAM 0.0001356 0.44247 2.29226
25 4TXI FAD 0.004214 0.41527 2.29226
26 2E5V FAD 0.00887 0.41473 2.29226
27 1ORR NAD 0.009105 0.4023 2.30548
28 3O7W SAM 0.00007245 0.43995 2.38095
29 2CI5 HCS 0.03732 0.40243 2.46479
30 3LCV SAM 0.0002865 0.45116 2.4911
31 1DL5 SAH 0.000009838 0.51694 2.52366
32 3VC1 SAH 0.00009397 0.49596 2.5641
33 3VC1 GST 0.00009397 0.49596 2.5641
34 2RGO FAD 0.002981 0.42758 2.5788
35 1H82 GZZ 0.009137 0.42463 2.5788
36 1H82 FAD 0.007674 0.42463 2.5788
37 1UWK URO 0.005557 0.4237 2.5788
38 1UWK NAD 0.005557 0.4237 2.5788
39 2CDU FAD 0.008723 0.40644 2.5788
40 1BXK NAD 0.006134 0.40453 2.5788
41 2V57 PRL 0.03032 0.40251 2.63158
42 1N2X SAM 0.0004758 0.44223 2.65781
43 1JQ3 AAT 0.0002479 0.46861 2.7027
44 3I53 SAH 0.0001299 0.45691 2.71084
45 3SQP FAD 0.01367 0.44833 2.71967
46 1JQD SAH 0.001232 0.43503 2.73973
47 2AOT SAH 0.0002057 0.42823 2.73973
48 1JQD HSM 0.004163 0.40869 2.73973
49 3GU3 SAH 0.00001082 0.56467 2.8169
50 2JJQ SAH 0.0001756 0.42249 2.86533
51 4J36 FAD 0.003562 0.4196 2.86533
52 4J36 1HR 0.006413 0.41916 2.86533
53 3LAD FAD 0.007291 0.4158 2.86533
54 3LXD FAD 0.00557 0.41369 2.86533
55 3ICR FAD 0.008276 0.40848 2.86533
56 3ICS FAD 0.009133 0.40765 2.86533
57 2XVE FAD 0.02246 0.40607 2.86533
58 1PN0 FAD 0.01523 0.40594 2.86533
59 1PN0 IPH 0.01586 0.40594 2.86533
60 4REP FAD 0.01065 0.40575 2.86533
61 4C3Y FAD 0.0133 0.40343 2.86533
62 4C3Y ANB 0.01719 0.4028 2.86533
63 1YXM ADE 0.001574 0.46553 2.9703
64 4NEC SAH 0.00003608 0.45391 3.0303
65 5ITV NAI 0.006237 0.40683 3.13725
66 5U8U FAD 0.009535 0.4257 3.15186
67 1N4W FAD 0.006115 0.42007 3.15186
68 4JDR FAD 0.006621 0.41668 3.15186
69 5KMS NAD 0.01978 0.40731 3.15186
70 3DXY SAM 0.00000887 0.56122 3.21101
71 3FPF MTA 0.00006377 0.40154 3.3557
72 3FPF TNA 0.00006377 0.40154 3.3557
73 3LKZ SFG 0.0000568 0.49386 3.42679
74 5LOG SAH 0.00007039 0.46184 3.43348
75 5KOK S9T 0.0002393 0.47066 3.4384
76 5KOK SAH 0.00004695 0.46847 3.4384
77 2ZWA SAH 0.0004847 0.4457 3.4384
78 5KOK R9T 0.001127 0.44078 3.4384
79 4MO2 FDA 0.003011 0.42739 3.4384
80 4MO2 FAD 0.004231 0.4221 3.4384
81 4EUE NAI 0.004591 0.4137 3.4384
82 3QFA FAD 0.01028 0.40926 3.4384
83 4CNK FAD 0.01179 0.40285 3.4384
84 2YVJ FAD 0.01147 0.40235 3.4384
85 5MZI FAD 0.02647 0.40215 3.4384
86 5MZI FYK 0.02732 0.40215 3.4384
87 3CH6 NAP 0.01262 0.4182 3.4965
88 3CH6 311 0.01262 0.4182 3.4965
89 4OBW SAM 0.0009033 0.44626 3.50195
90 4Z2S NDG 0.03385 0.40068 3.52113
91 4Z2S NAG 0.03385 0.40068 3.52113
92 5N5D SAM 0.00003471 0.47213 3.53982
93 3FRH SAH 0.0004791 0.4421 3.55731
94 4GQP B40 0.02751 0.40439 3.61446
95 2VDV SAM 0.000006591 0.56003 3.65854
96 3OU2 SAH 0.00002562 0.47947 3.66972
97 2ZFU SAH 0.00003602 0.47647 3.72093
98 3SSO SAH 0.0004404 0.46685 3.72493
99 3VSE SAH 0.00005826 0.43301 3.72493
100 5JAQ NAI 0.006044 0.41644 3.72493
101 5F2K OCA 0.004671 0.41338 3.72493
102 5F2K SAH 0.004671 0.41338 3.72493
103 1RSG FAD 0.008428 0.41303 3.72493
104 4M52 FAD 0.008906 0.41199 3.72493
105 3KLJ FAD 0.005427 0.41184 3.72493
106 1YY5 FAD 0.01172 0.40851 3.72493
107 5BUK FAD 0.01224 0.40768 3.72493
108 1NW5 SAM 0.00004866 0.46637 3.76176
109 2YY7 NAD 0.008403 0.40138 3.84615
110 1WG8 SAM 0.00004946 0.48415 3.85965
111 5KVA SAM 0.0000609 0.47349 3.95683
112 4POO SAM 0.0002532 0.45523 4
113 3P2E SAH 0.0001401 0.4545 4
114 3Q9T FAY 0.006317 0.41353 4.01146
115 3AYI HCI 0.01698 0.40759 4.01146
116 3AYI FAD 0.01636 0.40759 4.01146
117 2PT9 2MH 0.0001548 0.4787 4.04984
118 2PT9 S4M 0.00007779 0.47807 4.04984
119 3JWH SAH 0.000006556 0.4653 4.14747
120 2HQM FAD 0.003023 0.43253 4.17537
121 1V59 FAD 0.001564 0.448 4.1841
122 1V59 NAD 0.0004445 0.40042 4.1841
123 3C3Y SAH 0.001418 0.41127 4.21941
124 5XVK SAH 0.0005965 0.43825 4.22535
125 5MGZ SAH 0.00004228 0.49938 4.23729
126 2PZM UDP 0.009784 0.4111 4.24242
127 2PZM NAD 0.009784 0.4111 4.24242
128 1LSS NAD 0.0002647 0.46074 4.28571
129 3C6K SPD 0.0002512 0.47246 4.29799
130 3C6K MTA 0.0002512 0.47246 4.29799
131 3UOY NAP 0.003344 0.44795 4.29799
132 3UOY FAD 0.003344 0.44795 4.29799
133 1QO8 FAD 0.008377 0.41315 4.29799
134 3S5W FAD 0.004889 0.41128 4.29799
135 5M58 SAH 0.00009601 0.45612 4.34783
136 1R18 SAH 0.01372 0.40797 4.40529
137 1IY8 NAD 0.006205 0.40693 4.49438
138 4X9M FAD 0.005156 0.42044 4.54545
139 5FJN BE2 0.004959 0.42589 4.58453
140 5FJN FAD 0.004288 0.42589 4.58453
141 2BRY FAD 0.002775 0.4242 4.58453
142 5EB4 FAD 0.007569 0.41318 4.58453
143 5G3U FDA 0.007636 0.41102 4.58453
144 4FZV SAM 0.00004219 0.47426 4.60251
145 1G60 SAM 0.0003062 0.43549 4.61538
146 4II2 ATP 0.00506 0.40667 4.81928
147 2PX8 SAH 0.0002942 0.43003 4.83271
148 1BC5 SAH 0.003716 0.40601 4.83271
149 5BW4 SAM 0.00001815 0.47045 4.86891
150 4KRI SAH 0.000003285 0.5411 4.87106
151 3TKY SAH 0.00008842 0.45852 4.87106
152 5DNK SAH 0.00001209 0.44673 4.87106
153 2IID FAD 0.004995 0.43232 4.87106
154 2IID PHE 0.004995 0.43232 4.87106
155 1COY FAD 0.004599 0.42359 4.87106
156 1COY AND 0.01673 0.40996 4.87106
157 1KYZ SAH 0.01033 0.40823 4.87106
158 4USR FAD 0.007302 0.40637 4.87106
159 4FN4 NAD 0.006937 0.40361 5.11811
160 5F8F SFG 0.00003892 0.45342 5.15759
161 3BGD SAH 0.00002138 0.49686 5.38462
162 3BGD PM6 0.00004496 0.45564 5.38462
163 1RJD SAM 0.0003125 0.44236 5.38922
164 3DMH GMP 0.000001658 0.55094 5.44413
165 3DMH SAM 0.0000006805 0.5422 5.44413
166 4Z24 FAD 0.002038 0.44002 5.44413
167 1GY8 NAD 0.001223 0.43657 5.44413
168 2RAB NAD 0.005827 0.43619 5.44413
169 2RAB FAD 0.00276 0.43619 5.44413
170 4E70 N7I 0.003318 0.41703 5.44413
171 2YGM GLA NAG GAL FUC 0.01664 0.41185 5.44413
172 5MBX SP5 0.01756 0.40763 5.44413
173 5MBX FAD 0.01756 0.40763 5.44413
174 5FTW SAH 0.001851 0.42512 5.46875
175 2UYQ SAM 0.001909 0.46437 5.48387
176 4BLW AMP 0.0002171 0.47246 5.53633
177 4BLW SAH 0.0001675 0.46621 5.53633
178 1UKG MMA 0.03337 0.40425 5.55556
179 2P41 SAH 0.00001869 0.47457 5.57377
180 4IWN GEK 0.0000008303 0.55406 5.67686
181 5JCM FAD 0.02072 0.40953 5.73066
182 5JCM ISD 0.02135 0.40953 5.73066
183 5JCM NAD 0.02135 0.40953 5.73066
184 1FP2 SAH 0.01022 0.4024 5.73066
185 1I1N SAH 0.00000795 0.52275 5.75221
186 3A4T SFG 0.000007025 0.52171 5.83942
187 3A25 SAM 0.00004591 0.46016 5.98007
188 3FZG SAM 0.001005 0.40329 6
189 5MX4 HPA 0.03454 0.40022 6.00858
190 4HA6 FAD 0.0005268 0.46676 6.01719
191 1I9G SAM 0.01474 0.43145 6.07143
192 1Q0S SAH 0.0001619 0.46315 6.17761
193 3EVG SAH 0.00002123 0.5178 6.18182
194 2FJK 13P 0.01836 0.40564 6.22951
195 1U2Z SAH 0.0000008285 0.5541 6.30372
196 3QVP FAD 0.0003799 0.47298 6.30372
197 1BZL FAD 0.002582 0.46603 6.30372
198 4ITU 1HS 0.009646 0.41046 6.3197
199 4ITU NAI 0.005849 0.41046 6.3197
200 5E72 SAM 0.000007374 0.50987 6.35838
201 5E9W SAH 0.00005543 0.43213 6.41026
202 3QOX SAH 0.000002245 0.53655 6.59026
203 4KIB SAH 0.000002229 0.50531 6.59026
204 1ZMD FAD 0.00457 0.42562 6.59026
205 1ELI PYC 0.003576 0.42526 6.59026
206 1ZMD NAI 0.003857 0.40855 6.59026
207 4RSL FAD 0.008583 0.40674 6.59026
208 3ZNN FAD 0.01524 0.41181 6.62824
209 3ZNN 4WL 0.01524 0.41181 6.62824
210 2WSB NAD 0.008026 0.41207 6.69291
211 3HVJ 705 0.000003753 0.55217 6.78733
212 4TQG NDP 0.002344 0.42194 6.81115
213 4DMG SAM 0.0002527 0.49139 6.87023
214 3GDN FAD 0.0077 0.41476 6.87679
215 3GDN HBX 0.01092 0.41476 6.87679
216 5MW4 5JU 0.00001133 0.53583 6.88623
217 1QAN SAH 0.00001905 0.5038 6.96721
218 3Q87 SAM 0.00004966 0.48202 7.05882
219 3NUG NAD 0.0046 0.4124 7.28745
220 4BV6 FAD 0.003874 0.42684 7.44986
221 1YQZ FAD 0.01045 0.42063 7.44986
222 1RKX NAD 0.003554 0.41711 7.44986
223 3GRU AMP 0.00006852 0.47635 7.45763
224 1XSE NDP 0.01147 0.40531 7.45763
225 5E1M PRO PRO LYS ARG ILE ALA 0.00003047 0.50869 7.46888
226 5E1M SAH 0.00003047 0.50869 7.46888
227 4YUW S4M 0.002768 0.46647 7.56579
228 4YUW 4JU 0.002829 0.46647 7.56579
229 2EJU SAH 0.000005161 0.54478 7.73639
230 2WPF FAD 0.006287 0.44706 7.73639
231 2WPF WPF 0.007335 0.44521 7.73639
232 1FP1 SAH 0.003821 0.42294 7.73639
233 1EJ0 SAM 0.00004906 0.46258 7.77778
234 5THY SAH 0.0001933 0.4493 7.90123
235 3PFG SAM 0.0262 0.41509 7.98479
236 3PFG TLO 0.0262 0.41509 7.98479
237 4RDH AMP 0.005591 0.4187 7.98611
238 5X62 SAH 0.000002969 0.56195 8.02292
239 5THZ SAH 0.0002288 0.45512 8.14815
240 4YNU LGC 0.0005161 0.47217 8.30946
241 4YNU FAD 0.0004192 0.47217 8.30946
242 4MIG G3F 0.001538 0.4511 8.30946
243 3AD8 NAD 0.00265 0.42628 8.37438
244 3AD8 PYC 0.02234 0.4092 8.37438
245 3AD8 FAD 0.02234 0.4092 8.37438
246 1KYQ NAD 0.008382 0.40707 8.39416
247 1MO9 FAD 0.02107 0.4163 8.59599
248 3MQ2 SAH 0.0002422 0.47619 8.7156
249 1G55 SAH 0.00001114 0.49103 8.74636
250 5J60 FAD 0.008411 0.41119 8.75
251 1IM8 SAI 0.006825 0.41976 9.01639
252 2A14 SAH 0.0004704 0.43865 9.12547
253 5MPT SAH 0.00009896 0.45079 9.16905
254 1D4D FAD 0.004934 0.42416 9.16905
255 1VQW FAD 0.005639 0.41114 9.16905
256 2GVC FAD 0.006383 0.40885 9.16905
257 5JE0 SAH 0.000003174 0.5451 9.31174
258 5JE0 AZ8 0.000003174 0.5451 9.31174
259 5JGL SAM 0.000325 0.42566 9.34256
260 2F5Z FAD 0.004789 0.42473 9.375
261 3M6W SAM 0.0002381 0.42387 9.45559
262 1S7G APR 0.006902 0.40741 9.48617
263 4PNE SAH 0.00005504 0.48021 9.60265
264 5DM1 5D7 0.00001856 0.52517 9.73783
265 5DM1 SAH 0.00001723 0.52517 9.73783
266 5JJR SAH 0.00002993 0.51125 10.0287
267 3OFK SAH 0.0003655 0.45077 10.1852
268 1ZQ9 SAM 0.0003944 0.42618 10.8772
269 3EGV SAH 0.000002853 0.56273 11.0236
270 2NXE SAM 0.000005733 0.49426 11.0236
271 2YX1 SFG 0.0000005525 0.50448 11.3095
272 1KPG SAH 0.00006769 0.47164 11.4983
273 3TLJ SAH 0.00004272 0.48467 12.0344
274 2PXX SAH 0.0000422 0.49941 12.5581
275 1XDS SAM 0.0005468 0.47003 12.6074
276 4N49 SAM 0.0003534 0.43922 12.6074
277 2WA2 SAM 0.00005849 0.44978 12.6812
278 1JG3 ADN 0.0001978 0.43601 12.766
279 1GET NAP 0.005906 0.43716 12.894
280 1GET FAD 0.00555 0.43716 12.894
281 5CUQ NSC 0.0001193 0.48055 13.1086
282 3CTY FAD 0.009998 0.41156 13.1805
283 1QZZ SAM 0.002333 0.44046 13.467
284 1NV8 SAM 0.000004233 0.53607 13.7324
285 1NV8 MEQ 0.00002206 0.5044 13.7324
286 4RPL 3UC 0.005024 0.43979 13.7536
287 4RPL FAD 0.005382 0.43648 13.7536
288 3DUW SAH 0.00002002 0.48181 13.9013
289 2XYQ SAH 0.0002551 0.43603 14.4828
290 4YRY FAD 0.006381 0.41833 14.4928
291 4YRY NAD 0.01667 0.40795 14.4928
292 4DCM SAM 0.00002341 0.46025 14.6132
293 4QTU SAM 0.000008208 0.53 14.8148
294 4M73 SAH 0.000003905 0.54987 14.8368
295 4M73 M72 0.00005616 0.5017 14.8368
296 2HNK SAH 0.0001266 0.47425 15.0628
297 3A27 SAM 0.000004473 0.49634 15.0735
298 4KRG SAH 0.000003661 0.49405 15.1862
299 3H2B SAH 0.0000005691 0.53903 15.2709
300 3GDH SAH 0.00002716 0.4849 15.3527
301 1TPY SAH 0.00006926 0.47113 15.7895
302 1L1E SAH 0.0002816 0.45961 15.7895
303 2FK8 SAM 0.0002917 0.44211 15.7895
304 3AB1 FAD 0.006221 0.41689 15.7895
305 5GM1 SAH 0.00005478 0.4803 15.8249
306 1XTP SAI 0.00000366 0.50321 16.1417
307 1Z3C SA8 0.00004671 0.49442 17.1141
308 3BXO SAM 0.00001215 0.46321 17.1548
309 2DPM SAM 0.00006805 0.47137 17.2535
310 2XVM SAH 0.00003057 0.44677 17.5879
311 3EGI ADP 0.00008665 0.53459 17.9612
312 1KPH SAH 0.00006956 0.47114 18.4669
313 4XUC 43G 0.00000316 0.5505 18.8073
314 4XUC SAM 0.00000316 0.5505 18.8073
315 4HSU FAD 0.01109 0.40957 19.3548
316 4GUT FAD 0.01242 0.40908 19.3548
317 2PWY SAH 0.002042 0.4465 19.3798
318 4FC7 NAP 0.01292 0.40489 19.4946
319 4FC7 COA 0.01292 0.40489 19.4946
320 1XCL SAH 0.00001507 0.51841 19.5745
321 3X0D SAH 0.0000000004928 0.65377 19.7708
322 4X60 SFG 0.0000000646 0.47854 19.7708
323 3NDJ SAH 0.0004425 0.47318 19.7708
324 3NDJ JHZ 0.0004425 0.47318 19.7708
325 4X60 3XV 0.00000007072 0.47209 19.7708
326 3G2O SAM 0.00002092 0.47613 20.0669
327 1WY7 SAH 0.000003759 0.52111 20.7729
328 5T67 JHZ 0.0004264 0.47288 20.9169
329 5T67 SAH 0.0003667 0.4703 20.9169
330 4R6W SAH 0.00001118 0.45135 20.9302
331 2BZG SAH 0.000007307 0.49115 21.0526
332 3G89 SAM 0.000001606 0.49082 21.0526
333 4IV9 FAD 0.01233 0.40394 21.0526
334 5FA8 SAM 0.0000005879 0.56014 21.118
335 4C4A SAH 0.000000001527 0.63439 21.2034
336 3GCZ SAM 0.00003647 0.46373 21.2766
337 1VE3 SAM 0.00001474 0.52476 21.5859
338 1P1C SAH 0.0001376 0.46408 23.1156
339 5E8J SAH 0.00004046 0.52307 25
340 4YMH SAH 0.000009349 0.52196 25
341 1L3I SAH 0.00002034 0.4818 26.0417
342 3PT9 SAH 0.00001503 0.47701 26.3158
343 3FUU ADN 0.000238 0.4391 26.3158
344 1Y8Q ATP 0.0004731 0.436 26.3158
345 1Q9I TEO 0.01015 0.41983 26.3158
346 1Q9I FAD 0.01015 0.41983 26.3158
347 3NKS FAD 0.006124 0.41411 26.3158
348 3GWZ SAH 0.000793 0.40383 26.3158
349 4HXY NDP 0.008163 0.40191 26.3158
350 3GXO SAH 0.001344 0.40019 26.3158
351 5HJM MTA 0.000001635 0.56014 31.5789
352 2ZIF SAM 0.00001802 0.51531 31.5789
353 4AZT SAM 0.0001269 0.4837 31.5789
354 5HSA FAS 0.001248 0.44828 31.5789
355 4AZW SAM 0.0001766 0.44546 31.5789
356 2O07 MTA 0.0006246 0.44428 31.5789
357 2O07 SPD 0.0007399 0.44428 31.5789
358 5XVQ SAH 0.0008104 0.43285 31.5789
359 2Z3Y F2N 0.003392 0.43131 31.5789
360 2GAG NAD 0.002628 0.42993 31.5789
361 4TM3 FAD 0.02134 0.41127 31.5789
362 5L95 AMP 0.002237 0.40486 31.5789
363 4M38 SAH 0.00000001888 0.6036 35.5685
364 4M37 SAH 0.0001356 0.49258 35.5685
365 5ULP KB1 0.00001277 0.50813 36.8421
366 3T7S SAM 0.000009702 0.48721 36.8421
367 3S1S SAH 0.00005281 0.48094 36.8421
368 3UCL CYH 0.01363 0.41854 36.8421
369 3UCL FAD 0.01363 0.41854 36.8421
370 3UCL NAP 0.01489 0.41854 36.8421
371 4X7Y SAH 0.006043 0.41842 36.8421
372 2V3B FAD 0.006877 0.41194 36.8421
373 2V3A FAD 0.009095 0.40773 36.8421
374 4LWP SAH 0.000000000001679 0.73472 45.8453
375 4Y2H SAH 0.00000000000004519 0.89773 48.1375
376 4Y2H 49K 0.0000000000004096 0.85631 48.1375
Pocket No.: 2; Query (leader) PDB : 5DX8; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5dx8.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5DX8; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5dx8.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5DX8; Ligand: SFG; Similar sites found: 31
This union binding pocket(no: 4) in the query (biounit: 5dx8.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4FWE FAD 0.006089 0.42015 1.7192
2 3F8D FAD 0.01809 0.41574 2.16718
3 1X87 NAD 0.004028 0.40458 2.29226
4 3OID NDP 0.008683 0.40318 2.32558
5 1PS9 FAD 0.01351 0.40314 2.5788
6 4A6D SAM 0.01531 0.40252 2.86533
7 4UP3 FAD 0.01364 0.40202 2.86624
8 1E6E FAD 0.01146 0.40134 3.125
9 2I7C AAT 0.0002216 0.4022 3.53357
10 3D3W NAP 0.009642 0.40125 3.68852
11 1PR9 NAP 0.01026 0.4001 3.68852
12 4GLL NAD 0.008776 0.4018 4.45104
13 5G3U ITW 0.01275 0.40689 4.58453
14 4D42 W0I 0.01448 0.40848 4.60993
15 4D42 NAP 0.01448 0.40848 4.60993
16 3E1T FAD 0.01484 0.40313 4.87106
17 1G4U AF3 0.03233 0.40094 4.8913
18 2BD0 NAP 0.00947 0.4004 4.91803
19 2R4J FAD 0.003115 0.43997 5.44413
20 2R4J 13P 0.003115 0.43997 5.44413
21 4J56 FAD 0.01395 0.40517 7.16332
22 2J5V RGP 0.02137 0.41073 7.44986
23 1EFV AMP 0.02686 0.40057 7.45098
24 5GWX SAM 0.001725 0.40511 8.09859
25 5GWX SAR 0.001725 0.40511 8.09859
26 1MO9 KPC 0.01783 0.42024 8.59599
27 1ZGA SAH 0.01029 0.40229 10.6443
28 1T0S BML 0.02228 0.41297 17.4419
29 2BOS GLA GAL GLC 0.02281 0.40786 20.5882
30 2BOS GLA GAL GLC NBU 0.03054 0.40209 20.5882
31 2GAG FAD 0.01195 0.409 31.5789
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