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Receptor
PDB id Resolution Class Description Source Keywords
5DM1 1.8 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF THE PLANTAZOLICIN METHYLTRANSFERASE BPU COMPLEX WITH MONOAZOLIC DESMETHYLPZN ANALOG AND SAH BACILLUS PUMILUS ATCC 7061 N-METHYLTRANSFERASE PLANTAZOLICIN MONOAZOLIC DESMETHYLPZN TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: INSIGHTS INTO METHYLTRANSFERASE SPECIFICITY AND BIO OF DERIVATIVES OF THE ANTIBIOTIC PLANTAZOLICIN. ACS CHEM.BIOL. V. 10 1209 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:303;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAH A:302;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
5D7 A:301;
Valid;
none;
submit data
297.377 C12 H19 N5 O2 S [H]/N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DM1 1.8 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF THE PLANTAZOLICIN METHYLTRANSFERASE BPU COMPLEX WITH MONOAZOLIC DESMETHYLPZN ANALOG AND SAH BACILLUS PUMILUS ATCC 7061 N-METHYLTRANSFERASE PLANTAZOLICIN MONOAZOLIC DESMETHYLPZN TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: INSIGHTS INTO METHYLTRANSFERASE SPECIFICITY AND BIO OF DERIVATIVES OF THE ANTIBIOTIC PLANTAZOLICIN. ACS CHEM.BIOL. V. 10 1209 2015
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 4KWC - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5DM4 - 5DA C24 H27 N9 O3 S2 [H]/N=C(/N....
3 5DM1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5DM2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 4KWC - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5DM4 - 5DA C24 H27 N9 O3 S2 [H]/N=C(/N....
3 5DM1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5DM2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 4KWC - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5DM4 - 5DA C24 H27 N9 O3 S2 [H]/N=C(/N....
3 5DM1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5DM2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 5DM0 - 5D8 C18 H23 N7 O3 S2 [H]/N=C(N)....
6 4KVZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5DLY - 5D7 C12 H19 N5 O2 S [H]/N=C(/N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Ligand no: 2; Ligand: 5D7; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 5D7 1 1
2 5D8 0.44 0.723077
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DM1; Ligand: SAH; Similar sites found with APoc: 370
This union binding pocket(no: 1) in the query (biounit: 5dm1.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 2AOT SAH None
2 1JQD SAH None
3 3LCV SAM None
4 6BKK 308 None
5 4RJD TFP None
6 2FKA BEF None
7 1JQD HSM None
8 6BKL RIM None
9 6BKL EU7 None
10 4JCA CIT None
11 4RDH AMP 1.1236
12 4D79 ATP 1.1236
13 4RDI ATP 1.1236
14 5DZ2 212 1.49813
15 1NJR XYL 1.49813
16 1F8G NAD 1.49813
17 1XTP SAI 1.5748
18 4YMH SAH 1.66667
19 3MCT SAH 1.87266
20 1NW5 SAM 1.87266
21 1BW9 NAD 1.87266
22 1PJS NAD 1.87266
23 1VPE 3PG 1.87266
24 1A5Z NAD 1.87266
25 4TQG NDP 1.87266
26 2BO4 FLC 1.87266
27 3B1F NAD 1.87266
28 3B99 U51 1.87266
29 2BRY FAD 1.87266
30 3RKR NAP 1.9084
31 3KO0 TFP 1.9802
32 6ECU SAH 2.24719
33 2ZIF SAM 2.24719
34 5XNC MTA 2.24719
35 4O08 PO6 2.24719
36 3H8V ATP 2.24719
37 3TKA SAM 2.24719
38 6ECW SAH 2.24719
39 3C6K SPD 2.24719
40 2HK9 ATR 2.24719
41 5MB4 NAG 2.24719
42 3R7F CP 2.24719
43 3C6K MTA 2.24719
44 3U1T MLI 2.24719
45 6EOM ALA LYS 2.24719
46 4RSL FAD 2.24719
47 1QO8 FAD 2.24719
48 1RJW ETF 2.24719
49 4LWP SAH 2.62172
50 3P9C SAH 2.62172
51 6BQ6 TER 2.62172
52 1SQF SAM 2.62172
53 6FDF SAH 2.62172
54 3O01 DXC 2.62172
55 3FPF TNA 2.62172
56 3S5W FAD 2.62172
57 3FPF MTA 2.62172
58 3RLB VIB 2.62172
59 4YUW 4JU 2.62172
60 3QV1 NAD 2.62172
61 4YUW S4M 2.62172
62 1VJT NAD 2.62172
63 2A14 SAH 2.6616
64 2VCN ISZ 2.68199
65 4CQM NAP 2.68199
66 3BGD SAH 2.69231
67 3BGD PM6 2.69231
68 2VT3 ATP 2.7907
69 3PT9 SAH 2.99625
70 2JHP SAH 2.99625
71 1KYQ NAD 2.99625
72 5K7U SAM 2.99625
73 5KOH HCA 2.99625
74 3O03 NAP 2.99625
75 3L9W GSH 2.99625
76 3L9W AMP 2.99625
77 2FDW D3G 2.99625
78 1MO9 KPC 2.99625
79 1MO9 FAD 2.99625
80 1HYH NAD 2.99625
81 5FTW SAH 3.125
82 1QAN SAH 3.27869
83 2HNK SAH 3.34728
84 2YX1 SFG 3.37079
85 5FA5 MTA 3.37079
86 1KPG SAH 3.37079
87 4A6D SAM 3.37079
88 3GCZ SAM 3.37079
89 5JJR SAH 3.37079
90 5YJF 8WO 3.37079
91 5YJF SAH 3.37079
92 5YJI 8WO 3.37079
93 5YJI SAH 3.37079
94 3VYW SAM 3.37079
95 4N49 SAM 3.37079
96 4GQB 0XU 3.37079
97 2JK0 ASP 3.37079
98 3U31 NAD 3.37079
99 1NML CIT 3.37079
100 1BXK NAD 3.37079
101 3SQP FAD 3.37079
102 4UCI SAM 3.37079
103 5BRT FAD 3.37079
104 2YG3 FAD 3.37079
105 4D7E FAD 3.37079
106 1Q0S SAH 3.4749
107 4POO SAM 3.5
108 3MB5 SAM 3.52941
109 4XUC SAM 3.66972
110 4XUC 43G 3.66972
111 2BD0 NAP 3.68852
112 1FWV SGA MAG FUC 3.73134
113 5YF1 SFG 3.74532
114 2EJU SAH 3.74532
115 5YF1 8V0 3.74532
116 1I9G SAM 3.74532
117 1BC5 SAH 3.74532
118 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.74532
119 1Y8Q ATP 3.74532
120 1P77 ATR 3.74532
121 6DNT NAD 3.74532
122 5F2K OCA 3.74532
123 5F2K SAH 3.74532
124 1GZ6 NAI 3.74532
125 5BUK FAD 3.74532
126 5ZYN FAD 3.74532
127 1L1E SAH 4.11985
128 5THY SAH 4.11985
129 5THZ SAH 4.11985
130 2O07 MTA 4.11985
131 4BLW SAH 4.11985
132 4BLW AMP 4.11985
133 3ZPG 5GP 4.11985
134 1GY8 NAD 4.11985
135 1CT9 AMP 4.11985
136 2O07 SPD 4.11985
137 1TPY SAH 4.11985
138 1P31 EPU 4.11985
139 4X7Y SAH 4.11985
140 4ARE FLC 4.11985
141 4RL4 PPV 4.24528
142 3VSE SAH 4.49438
143 1FP2 SAH 4.49438
144 3TKY SAH 4.49438
145 5HJM MTA 4.49438
146 1U2Z SAH 4.49438
147 5W7R SAH 4.49438
148 5GWX SAR 4.49438
149 5GWX SAM 4.49438
150 5XLX SAH 4.49438
151 1X87 NAD 4.49438
152 1JQ3 AAT 4.49438
153 1FP2 HMO 4.49438
154 3U4C NDP 4.49438
155 5W7R 9Z7 4.49438
156 2VGD XYP XYP 4.58716
157 1XCL SAH 4.68085
158 2EWM NAD 4.81928
159 3GEG NAD 4.8583
160 5E9W SAH 4.86891
161 1QZZ SAM 4.86891
162 3A25 SAM 4.86891
163 2WA2 SAM 4.86891
164 5BJX NAD 4.86891
165 2IZ1 ATR 4.86891
166 5BJX UDP 4.86891
167 3IHG FAD 4.86891
168 5ICE 2H4 4.86891
169 4RQL SNE 4.86891
170 5X62 SAH 4.86891
171 4OM8 NAD 4.86891
172 2WW2 SWA 4.86891
173 5ICE SAH 4.86891
174 1OBB NAD 4.86891
175 3ABI NAD 4.86891
176 6F97 FAD 4.86891
177 3WV8 ATP 5.04587
178 5LOG SAH 5.15021
179 1L5Y BEF 5.16129
180 2BZG SAH 5.17241
181 1KPH SAH 5.24345
182 3MAG SAH 5.24345
183 3WBZ ATP 5.24345
184 5LX9 OLB 5.24345
185 6H3O FAD 5.24345
186 1PL6 NAD 5.24345
187 3HVJ 705 5.42986
188 1P1C SAH 5.52764
189 2HMT NAI 5.55556
190 1FP1 SAH 5.61798
191 4KRG SAH 5.61798
192 1XDS SAM 5.61798
193 5ULP KB1 5.61798
194 3EVG SAH 5.61798
195 2P41 SAH 5.61798
196 6B92 SAH 5.61798
197 3T3Z 9PL 5.61798
198 1RZM E4P 5.61798
199 5CUQ NSC 5.61798
200 4LOC OXM 5.61798
201 2YP9 SIA CMO 5.61798
202 3H5N ATP 5.61798
203 4YNU FAD 5.61798
204 3MPB FRU 5.69106
205 1LSS NAD 5.71429
206 2CBZ ATP 5.90717
207 6GFK SAH 5.9761
208 3A27 SAM 5.99251
209 1G55 SAH 5.99251
210 1LVL NAD 5.99251
211 2P9T 3PG 5.99251
212 1Y9G FRU 5.99251
213 5JE8 NAD 5.99251
214 3FZG SAM 6
215 2I7C AAT 6.00707
216 3T7S SAM 6.36704
217 3G2O SAM 6.36704
218 1F3L SAH 6.36704
219 5ERG SAM 6.36704
220 4LZB URA 6.36704
221 2OBF SAH 6.36704
222 5F7J ADE 6.36704
223 2OBF F83 6.36704
224 1Z45 NAD 6.36704
225 3Q87 SAM 6.4
226 2PT9 S4M 6.54206
227 5Y02 HBX 6.54206
228 2PT9 2MH 6.54206
229 3D3W NAP 6.55738
230 4IF4 BEF 6.73077
231 4DMG SAM 6.74157
232 5W7M SAH 6.74157
233 4UP4 GAL NAG 6.74157
234 6C4N NAP 6.74157
235 4KRI SAH 7.11611
236 5JGL SAM 7.11611
237 5FUB SAH 7.11611
238 4OBW SAM 7.11611
239 3LKZ SFG 7.11611
240 3S1S SAH 7.11611
241 4RVG SAM 7.11611
242 5IUY BOG 7.11611
243 4RVG TYD 7.11611
244 1V6A TRE 7.11611
245 3C3Y SAH 7.173
246 5KVA SAM 7.19424
247 2Q28 ADP 7.2695
248 1G60 SAM 7.30769
249 2VDV SAM 7.31707
250 5XJ7 87O 7.46269
251 5T67 JHZ 7.49064
252 5T67 SAH 7.49064
253 1I1N SAH 7.52212
254 3JRS A8S 7.69231
255 5WP4 SAH 7.86517
256 3ELW SAM 7.86517
257 3ELW GP3 7.86517
258 3EVF SAH 7.86517
259 3KP6 SAL 7.94702
260 1SBR VIB 8
261 3GWZ SAH 8.2397
262 3GXO SAH 8.2397
263 1V59 NAD 8.2397
264 2ZFU SAH 8.37209
265 4RYV ZEA 8.3871
266 5YEC ATP 8.40336
267 5MPT SAH 8.61423
268 6C8R SAH 8.61423
269 2UYQ SAM 8.61423
270 6C8R EQV 8.61423
271 1UAY ADN 8.67769
272 4AZW SAM 8.98876
273 5E72 SAM 8.98876
274 2DPM SAM 8.98876
275 5DNK SAH 8.98876
276 5MW4 5JU 8.98876
277 5UGW GSH 9.14286
278 4II2 ATP 9.20245
279 4E70 N7I 9.3633
280 4YSW URC 9.3633
281 3K6V CIT 9.60452
282 5ZZ6 ADP 9.61539
283 5ZZ6 NAD 9.61539
284 5L95 AMP 9.67742
285 5GM1 SAH 9.73783
286 6C5B SAH 9.73783
287 5DX1 SFG 9.73783
288 5DXA SFG 9.73783
289 5DX8 SFG 9.73783
290 5DX0 SFG 9.73783
291 5DWQ SFG 9.73783
292 6ARJ BW4 9.73783
293 6ARJ SAH 9.73783
294 1L3I SAH 9.89583
295 1GG6 APL 9.92366
296 4DCM SAM 10.1124
297 5HSA FAS 10.1124
298 1PVC ILE SER GLU VAL 10.2941
299 5OCA 9QZ 10.3175
300 1KYZ SAH 10.4869
301 1KYZ FER 10.4869
302 5MGZ SAH 10.5932
303 5N5D SAM 10.6195
304 4YAC NAI 10.7744
305 2PWY SAH 10.8527
306 5BW4 SAM 10.8614
307 5U19 SAH 10.8614
308 5U19 827 10.8614
309 3MQ2 SAH 11.0092
310 3JWH SAH 11.0599
311 5CQG 55C 11.236
312 5JE0 SAH 11.336
313 5JE0 AZ8 11.336
314 1ZEM NAD 11.4504
315 3DXY SAM 11.4679
316 4Y9D NAI 11.6105
317 4OPC PGT 11.6105
318 4OPC FDA 11.6105
319 4EUE NAI 11.985
320 6B3A SAM 12.3596
321 4NEC SAH 12.5
322 5W7K SAH 12.7341
323 5FWA J7C 12.7341
324 3AIH BMA MAN MAN 12.9032
325 2PX8 SAH 13.0112
326 2PXX SAH 13.0233
327 5UFN SAH 13.0252
328 5FA8 SAM 13.0435
329 4FN4 NAD 13.7795
330 5BSZ SAH 14
331 3P2E SAH 14.2222
332 1DL5 SAH 14.2322
333 2Q1W NAD 14.2322
334 2NW9 FT6 14.6067
335 3QOX SAH 14.6067
336 6F5Z SAH 14.7186
337 1ZGA SAH 15.6863
338 1Z3C SA8 15.7303
339 4PIO AVI 15.7303
340 4PIO SAH 15.7303
341 1GPM AMP 15.7303
342 1VE3 SAM 17.1806
343 2CDU ADP 17.2285
344 3H2B SAH 17.2414
345 3BXO SAM 17.5732
346 5E1M PRO PRO LYS ARG ILE ALA 17.8423
347 5E1M SAH 17.8423
348 3PFG SAM 18.2509
349 3PFG TLO 18.2509
350 5W97 CHD 18.3673
351 5KOK SAH 18.7266
352 5KOK S9T 18.7266
353 5KOK R9T 18.7266
354 5F8F SFG 18.7266
355 1R18 SAH 18.9427
356 4KIB SAH 19.1011
357 6DUB SAH 19.3694
358 6ECT SAM 20.2247
359 5E8J SAH 20.4545
360 6GKV SAH 20.5993
361 2XVM SAH 20.603
362 2W41 ADP 20.9738
363 4PNE SAH 21.3483
364 3LST SAH 21.7228
365 3WH2 FLC 23.1293
366 4R6W SAH 23.6434
367 4R6W PC 23.6434
368 3OU2 SAH 24.7706
369 1T0S BML 26.7442
370 1JG3 ADN 28.0851
Pocket No.: 2; Query (leader) PDB : 5DM1; Ligand: 5D7; Similar sites found with APoc: 384
This union binding pocket(no: 2) in the query (biounit: 5dm1.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 2AOT SAH None
2 1JQD SAH None
3 3LCV SAM None
4 6BKK 308 None
5 4RJD TFP None
6 2FKA BEF None
7 6BOC RIM None
8 6BKL EU7 None
9 6BKL RIM None
10 1JQD HSM None
11 2AOU CQA None
12 1MID LAP None
13 4RDH AMP 1.1236
14 4D79 ATP 1.1236
15 4RDI ATP 1.1236
16 5DZ2 212 1.49813
17 1NJR XYL 1.49813
18 1F8G NAD 1.49813
19 1XTP SAI 1.5748
20 4YMH SAH 1.66667
21 3MCT SAH 1.87266
22 1NW5 SAM 1.87266
23 1BW9 NAD 1.87266
24 1PJS NAD 1.87266
25 1VPE 3PG 1.87266
26 1A5Z NAD 1.87266
27 4TQG NDP 1.87266
28 3B1F NAD 1.87266
29 3B99 U51 1.87266
30 2BRY FAD 1.87266
31 3RKR NAP 1.9084
32 3KO0 TFP 1.9802
33 6ECU SAH 2.24719
34 2ZIF SAM 2.24719
35 5XNC MTA 2.24719
36 3H8V ATP 2.24719
37 4O08 PO6 2.24719
38 3TKA SAM 2.24719
39 3C6K SPD 2.24719
40 6ECW SAH 2.24719
41 2HK9 ATR 2.24719
42 5MB4 NAG 2.24719
43 3C6K MTA 2.24719
44 3U1T MLI 2.24719
45 4RSL FAD 2.24719
46 1RJW ETF 2.24719
47 4LWP SAH 2.62172
48 3P9C SAH 2.62172
49 6BQ6 TER 2.62172
50 1SQF SAM 2.62172
51 6FDF SAH 2.62172
52 3O01 DXC 2.62172
53 3FPF TNA 2.62172
54 3S5W FAD 2.62172
55 3FPF MTA 2.62172
56 3RLB VIB 2.62172
57 2YVK MRU 2.62172
58 3QV1 NAD 2.62172
59 4YUW S4M 2.62172
60 4YUW 4JU 2.62172
61 1VJT NAD 2.62172
62 2A14 SAH 2.6616
63 2VCN ISZ 2.68199
64 4CQM NAP 2.68199
65 3BGD SAH 2.69231
66 3BGD PM6 2.69231
67 2VT3 ATP 2.7907
68 3PT9 SAH 2.99625
69 2JHP SAH 2.99625
70 5K7U SAM 2.99625
71 1KYQ NAD 2.99625
72 5IL1 SAM 2.99625
73 3L9W GSH 2.99625
74 3O03 NAP 2.99625
75 3L9W AMP 2.99625
76 5KOH HCA 2.99625
77 1HYH NAD 2.99625
78 5O4J PJL 2.99625
79 5O4J SAH 2.99625
80 5O4J 9KH 2.99625
81 5FTW SAH 3.125
82 1QAN SAH 3.27869
83 2HNK SAH 3.34728
84 2YX1 SFG 3.37079
85 5FA5 MTA 3.37079
86 1KPG SAH 3.37079
87 4A6D SAM 3.37079
88 3GCZ SAM 3.37079
89 5JJR SAH 3.37079
90 5YJF 8WO 3.37079
91 5YJF SAH 3.37079
92 5YJI 8WO 3.37079
93 5YJI SAH 3.37079
94 3VYW SAM 3.37079
95 4N49 SAM 3.37079
96 4GQB 0XU 3.37079
97 2JK0 ASP 3.37079
98 3U31 NAD 3.37079
99 1NML CIT 3.37079
100 1BXK NAD 3.37079
101 4UCI SAM 3.37079
102 5BRT FAD 3.37079
103 3SQP FAD 3.37079
104 4D7E FAD 3.37079
105 4LYQ MAN BMA BMA 3.37079
106 5GVR LMR 3.4188
107 1Q0S SAH 3.4749
108 4POO SAM 3.5
109 3MB5 SAM 3.52941
110 4JMU 1ML 3.57143
111 4XUC 43G 3.66972
112 4XUC SAM 3.66972
113 2BD0 NAP 3.68852
114 1FWV SGA MAG FUC 3.73134
115 5YF1 SFG 3.74532
116 2EJU SAH 3.74532
117 5YF1 8V0 3.74532
118 1I9G SAM 3.74532
119 1BC5 SAH 3.74532
120 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.74532
121 1Y8Q ATP 3.74532
122 1P77 ATR 3.74532
123 1VJ7 GPX 3.74532
124 6DNT NAD 3.74532
125 5F2K OCA 3.74532
126 5F2K SAH 3.74532
127 1GZ6 NAI 3.74532
128 1J0D 5PA 3.74532
129 1L1E SAH 4.11985
130 5THY SAH 4.11985
131 5THZ SAH 4.11985
132 2O07 MTA 4.11985
133 4BLW SAH 4.11985
134 1P31 EPU 4.11985
135 4BLW AMP 4.11985
136 3ZPG 5GP 4.11985
137 2O07 SPD 4.11985
138 1GY8 NAD 4.11985
139 1CT9 AMP 4.11985
140 1TPY SAH 4.11985
141 5I34 GDP 4.11985
142 4ARE FLC 4.11985
143 1P3D UMA 4.11985
144 4HBM 0Y7 4.16667
145 4RL4 PPV 4.24528
146 3GD8 GOL 4.4843
147 3VSE SAH 4.49438
148 1FP2 SAH 4.49438
149 3TKY SAH 4.49438
150 5HJM MTA 4.49438
151 1U2Z SAH 4.49438
152 5W7R SAH 4.49438
153 5GWX SAR 4.49438
154 5GWX SAM 4.49438
155 5XLX SAH 4.49438
156 1JQ3 AAT 4.49438
157 1X87 NAD 4.49438
158 1FP2 HMO 4.49438
159 3U4C NDP 4.49438
160 5W7R 9Z7 4.49438
161 5A3B APR 4.49438
162 2VGD XYP XYP 4.58716
163 1XCL SAH 4.68085
164 2V57 PRL 4.73684
165 6BJO DUY 4.8
166 2EWM NAD 4.81928
167 3GEG NAD 4.8583
168 5E9W SAH 4.86891
169 1QZZ SAM 4.86891
170 3A25 SAM 4.86891
171 5GG9 8GM 4.86891
172 2WA2 SAM 4.86891
173 5BJX NAD 4.86891
174 2IZ1 ATR 4.86891
175 5ICE SAH 4.86891
176 3IHG FAD 4.86891
177 5BJX UDP 4.86891
178 4RQL SNE 4.86891
179 4OM8 NAD 4.86891
180 5ICE 2H4 4.86891
181 5X62 SAH 4.86891
182 1OBB NAD 4.86891
183 3ABI NAD 4.86891
184 6F97 FAD 4.86891
185 3WV8 ATP 5.04587
186 5LOG SAH 5.15021
187 1L5Y BEF 5.16129
188 2BZG SAH 5.17241
189 1KPH SAH 5.24345
190 3MAG SAH 5.24345
191 3WBZ ATP 5.24345
192 1PL6 NAD 5.24345
193 3HVJ 705 5.42986
194 1P1C SAH 5.52764
195 2HMT NAI 5.55556
196 1FP1 SAH 5.61798
197 4KRG SAH 5.61798
198 1XDS SAM 5.61798
199 5ULP KB1 5.61798
200 3EVG SAH 5.61798
201 2P41 SAH 5.61798
202 6B92 SAH 5.61798
203 3T3Z 9PL 5.61798
204 5CUQ NSC 5.61798
205 3WIR BGC 5.61798
206 1RZM E4P 5.61798
207 4LOC OXM 5.61798
208 2YP9 SIA CMO 5.61798
209 3H5N ATP 5.61798
210 3MPB FRU 5.69106
211 1LSS NAD 5.71429
212 2CBZ ATP 5.90717
213 6GFK SAH 5.9761
214 3A27 SAM 5.99251
215 1G55 SAH 5.99251
216 1LVL NAD 5.99251
217 2P9T 3PG 5.99251
218 1Y9G FRU 5.99251
219 5JE8 NAD 5.99251
220 3FZG SAM 6
221 2I7C AAT 6.00707
222 4OGQ 7PH 6.14525
223 3T7S SAM 6.36704
224 3G2O SAM 6.36704
225 1F3L SAH 6.36704
226 5ERG SAM 6.36704
227 2OBF SAH 6.36704
228 5F7J ADE 6.36704
229 2OBF F83 6.36704
230 1Z45 NAD 6.36704
231 3Q87 SAM 6.4
232 2PT9 S4M 6.54206
233 5Y02 HBX 6.54206
234 2PT9 2MH 6.54206
235 3D3W NAP 6.55738
236 1PR9 NAP 6.55738
237 3WW2 SF9 6.64062
238 4IF4 BEF 6.73077
239 4DMG SAM 6.74157
240 6C4N NAP 6.74157
241 5W7M SAH 6.74157
242 4UP4 GAL NAG 6.74157
243 5URY PAM 6.84932
244 6C0B MLI 7.05128
245 4KRI SAH 7.11611
246 5JGL SAM 7.11611
247 5FUB SAH 7.11611
248 4OBW SAM 7.11611
249 3LKZ SFG 7.11611
250 3S1S SAH 7.11611
251 5IUY BOG 7.11611
252 4RVG SAM 7.11611
253 4RVG TYD 7.11611
254 1V6A TRE 7.11611
255 3C3Y SAH 7.173
256 5KVA SAM 7.19424
257 2Q28 ADP 7.2695
258 1G60 SAM 7.30769
259 2VDV SAM 7.31707
260 5XJ7 87O 7.46269
261 5T67 JHZ 7.49064
262 5T67 SAH 7.49064
263 1I1N SAH 7.52212
264 3JRS A8S 7.69231
265 5WP4 SAH 7.86517
266 4ZDJ UTP 7.86517
267 3ELW SAM 7.86517
268 3ELW GP3 7.86517
269 3GWZ SAH 8.2397
270 3GXO SAH 8.2397
271 1V59 NAD 8.2397
272 2R68 SUP 8.2397
273 1S8G DAO 8.26446
274 2ZFU SAH 8.37209
275 4RYV ZEA 8.3871
276 5YEC ATP 8.40336
277 5MPT SAH 8.61423
278 6C8R SAH 8.61423
279 2UYQ SAM 8.61423
280 6C8R EQV 8.61423
281 1UAY ADN 8.67769
282 4AZW SAM 8.98876
283 5E72 SAM 8.98876
284 2DPM SAM 8.98876
285 5DNK SAH 8.98876
286 5OJ7 AR6 8.98876
287 5MW4 5JU 8.98876
288 5UGW GSH 9.14286
289 4II2 ATP 9.20245
290 4E70 N7I 9.3633
291 1Q19 SSC 9.3633
292 3K6V CIT 9.60452
293 5ZZ6 ADP 9.61539
294 5ZZ6 NAD 9.61539
295 5L95 AMP 9.67742
296 5GM1 SAH 9.73783
297 6C5B SAH 9.73783
298 5DX1 SFG 9.73783
299 5DXA SFG 9.73783
300 5DX8 SFG 9.73783
301 5DX0 SFG 9.73783
302 5DWQ SFG 9.73783
303 6ARJ BW4 9.73783
304 6ARJ SAH 9.73783
305 1W6F ISZ 9.73783
306 1L3I SAH 9.89583
307 1GG6 APL 9.92366
308 4DCM SAM 10.1124
309 4TR9 ASP TRP ASN 10.1124
310 6EYT UDP 10.1124
311 5HSA FAS 10.1124
312 1PVC ILE SER GLU VAL 10.2941
313 5OCA 9QZ 10.3175
314 1KYZ SAH 10.4869
315 1KYZ FER 10.4869
316 5MGZ SAH 10.5932
317 5N5D SAM 10.6195
318 4YAC NAI 10.7744
319 2PWY SAH 10.8527
320 5BW4 SAM 10.8614
321 5U19 827 10.8614
322 5U19 SAH 10.8614
323 3MQ2 SAH 11.0092
324 3JWH SAH 11.0599
325 5JE0 AZ8 11.336
326 5JE0 SAH 11.336
327 1ZEM NAD 11.4504
328 3DXY SAM 11.4679
329 4Y9D NAI 11.6105
330 4OPC PGT 11.6105
331 4OPC FDA 11.6105
332 3OGV PTQ 11.6105
333 4EUE NAI 11.985
334 6B3A SAM 12.3596
335 4NEC SAH 12.5
336 5W7K SAH 12.7341
337 5FWA J7C 12.7341
338 3AIH BMA MAN MAN 12.9032
339 2PX8 SAH 13.0112
340 2PXX SAH 13.0233
341 5UFN SAH 13.0252
342 5FA8 SAM 13.0435
343 4FN4 NAD 13.7795
344 5BSZ SAH 14
345 3P2E SAH 14.2222
346 1DL5 SAH 14.2322
347 2Q1W NAD 14.2322
348 2NW9 FT6 14.6067
349 3QOX SAH 14.6067
350 6F5Z SAH 14.7186
351 3RMK BML 15.6627
352 1ZGA SAH 15.6863
353 1Z3C SA8 15.7303
354 4PIO AVI 15.7303
355 4PIO SAH 15.7303
356 1VE3 SAM 17.1806
357 2CDU ADP 17.2285
358 3H2B SAH 17.2414
359 3BXO SAM 17.5732
360 5E1M PRO PRO LYS ARG ILE ALA 17.8423
361 5E1M SAH 17.8423
362 3PFG TLO 18.2509
363 3PFG SAM 18.2509
364 1XPJ TLA 18.254
365 5KOK SAH 18.7266
366 5KOK S9T 18.7266
367 5KOK R9T 18.7266
368 5F8F SFG 18.7266
369 1R18 SAH 18.9427
370 4KIB SAH 19.1011
371 6DUB SAH 19.3694
372 6ECT SAM 20.2247
373 5E8J SAH 20.4545
374 6GKV SAH 20.5993
375 2XVM SAH 20.603
376 2W41 ADP 20.9738
377 4PNE SAH 21.3483
378 3LST SAH 21.7228
379 4R6W SAH 23.6434
380 4R6W PC 23.6434
381 3OU2 SAH 24.7706
382 1T0S BML 26.7442
383 1JG3 ADN 28.0851
384 3RF4 FUN 39.6552
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