Receptor
PDB id Resolution Class Description Source Keywords
5CTW 1.48 Å EC: 5.99.1.3 CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYR COMPLEXED WITH A FRAGMENT STAPHYLOCOCCUS AUREUS DNA GYRASE GYRB FRAGMENT-BASED SCREENING STRUCTURE-BASED ISOMERASE-ISOMERASE INHIBITOR COMPLEX
Ref.: FRAGMENT-BASED DISCOVERY OF DNA GYRASE INHIBITORS T THE ATPASE SUBUNIT OF GYRB. BIOORG.MED.CHEM.LETT. V. 26 1314 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG B:302;
A:302;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
24.305 Mg [Mg+2...
MPD B:305;
B:306;
A:304;
A:305;
B:304;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
118.174 C6 H14 O2 C[C@@...
55D A:301;
B:301;
 Valid;
Valid;
 none;
none;
 submit data
212.269 C9 H12 N2 O2 S CCCC(...
CL A:303;
B:303;
 Invalid;
Invalid;
 none;
none;
 submit data
35.453 Cl [Cl-]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3TTZ 1.63 Å EC: 5.99.1.3 CRYSTAL STRUCTURE OF A TOPOISOMERASE ATPASE INHIBITOR STAPHYLOCOCCUS AUREUS PROTEIN-INHIBITOR COMPLEX ATP-BINDING STRUCTURE-BASED DRUGANTIMICROBIAL ISOMERASE-ISOMERASE INHIBITOR COMPLEX
Ref.: PYRROLAMIDE DNA GYRASE INHIBITORS: OPTIMIZATION OF ANTIBACTERIAL ACTIVITY AND EFFICACY. BIOORG.MED.CHEM.LETT. V. 21 7416 2011
Members (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 12 families.
1 5D7D - 57X C17 H15 N5 O S CCCN1c2c(c....
2 5CTY ic50 = 0.265 uM 55H C14 H9 N5 O S c1cc(cnc1)....
3 5D7R ic50 = 0.013 uM 57Y C19 H16 N4 O4 S CCCc1c(ccc....
4 5CTW - 55D C9 H12 N2 O2 S CCCC(=O)Nc....
5 5CTU - 54X C10 H6 N2 O S2 c1cc(sc1)c....
6 3U2D - 08B C16 H18 Br N5 O3 Cc1c(cc([n....
7 5CTX ic50 = 1.32 uM 55G C20 H13 N5 O S c1ccc(cc1)....
8 3TTZ ic50 = 0.004 uM 07N C15 H15 Cl2 F N4 O3 S Cc1c(c(c([....
9 5D6Q ic50 = 5.8 uM 57V C17 H17 N5 O S CCNC(=O)Nc....
10 3U2K - 087 C17 H18 Cl3 N5 O2 Cc1c(c(c([....
11 5D6P ic50 = 2.5 uM 57U C11 H14 N4 O2 S CCNC(=O)Nc....
12 5Z9P - AX7 C7 H7 N3 c1ccc2c(c1....
13 5D7C ic50 = 0.14 uM 57W C20 H18 N6 O CCNC(=O)Nc....
14 6TCK - N1N C21 H15 Cl2 N3 O4 S Cc1c(c(c([....
15 5CPH - EVO C14 H10 N2 O c1ccc2c(c1....
70% Homology Family (20)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5D7D - 57X C17 H15 N5 O S CCCN1c2c(c....
2 5CTY ic50 = 0.265 uM 55H C14 H9 N5 O S c1cc(cnc1)....
3 5D7R ic50 = 0.013 uM 57Y C19 H16 N4 O4 S CCCc1c(ccc....
4 5CTW - 55D C9 H12 N2 O2 S CCCC(=O)Nc....
5 5CTU - 54X C10 H6 N2 O S2 c1cc(sc1)c....
6 3U2D - 08B C16 H18 Br N5 O3 Cc1c(cc([n....
7 5CTX ic50 = 1.32 uM 55G C20 H13 N5 O S c1ccc(cc1)....
8 3TTZ ic50 = 0.004 uM 07N C15 H15 Cl2 F N4 O3 S Cc1c(c(c([....
9 5D6Q ic50 = 5.8 uM 57V C17 H17 N5 O S CCNC(=O)Nc....
10 3U2K - 087 C17 H18 Cl3 N5 O2 Cc1c(c(c([....
11 5D6P ic50 = 2.5 uM 57U C11 H14 N4 O2 S CCNC(=O)Nc....
12 5Z9P - AX7 C7 H7 N3 c1ccc2c(c1....
13 5D7C ic50 = 0.14 uM 57W C20 H18 N6 O CCNC(=O)Nc....
14 6TCK - N1N C21 H15 Cl2 N3 O4 S Cc1c(c(c([....
15 5CPH - EVO C14 H10 N2 O c1ccc2c(c1....
16 4P8O - 883 C19 H16 F N7 O CCNC(=O)Nc....
17 6Y8N ic50 = 9 nM OGH C21 H21 F N8 O Cc1ncc(cn1....
18 6Y8L - NOV C31 H36 N2 O11 Cc1c(ccc2c....
19 4B6C ic50 = 0.69 uM B5U C27 H34 N6 O2 Cc1ccc(cc1....
20 4BAE ic50 = 3 nM RWX C19 H21 Br Cl N7 O4 S Cc1c(c(c([....
50% Homology Family (67)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4URL ic50 = 500 nM XAM C44 H60 Cl2 N4 O14 Cc1c(c(c([....
2 5CTW - 55D C9 H12 N2 O2 S CCCC(=O)Nc....
3 5CTU - 54X C10 H6 N2 O S2 c1cc(sc1)c....
4 3U2D - 08B C16 H18 Br N5 O3 Cc1c(cc([n....
5 5CTX ic50 = 1.32 uM 55G C20 H13 N5 O S c1ccc(cc1)....
6 3TTZ ic50 = 0.004 uM 07N C15 H15 Cl2 F N4 O3 S Cc1c(c(c([....
7 5D6Q ic50 = 5.8 uM 57V C17 H17 N5 O S CCNC(=O)Nc....
8 3U2K - 087 C17 H18 Cl3 N5 O2 Cc1c(c(c([....
9 5D6P ic50 = 2.5 uM 57U C11 H14 N4 O2 S CCNC(=O)Nc....
10 5Z9P - AX7 C7 H7 N3 c1ccc2c(c1....
11 5D7C ic50 = 0.14 uM 57W C20 H18 N6 O CCNC(=O)Nc....
12 6TCK - N1N C21 H15 Cl2 N3 O4 S Cc1c(c(c([....
13 5CPH - EVO C14 H10 N2 O c1ccc2c(c1....
14 6YD9 ic50 = 110 nM ON2 C16 H15 Cl2 N5 O2 S Cc1c(c(c([....
15 6F94 ic50 = 0.099 uM D0H C23 H25 N5 O2 CCNC(=O)Nc....
16 5Z9Q - HX4 C9 H9 N3 c1ccc(cc1)....
17 6KZX ic50 = 0.2 uM E0L C18 H15 N3 O4 CNc1cccc2c....
18 5Z4H - AX7 C7 H7 N3 c1ccc2c(c1....
19 5Z9L - 8H8 C7 H4 F N O c1cc(c(cc1....
20 5Z9E - AX7 C7 H7 N3 c1ccc2c(c1....
21 1KZN Kd = 1.2 nM CBN C35 H37 Cl N2 O11 Cc1ccc([nH....
22 1AJ6 Kd = 1.2 uM NOV C31 H36 N2 O11 Cc1c(ccc2c....
23 5Z9B - AX7 C7 H7 N3 c1ccc2c(c1....
24 6KZZ ic50 = 0.0017 uM E0R C18 H15 N3 O4 CNc1cccc2c....
25 5MMO - 9JG C22 H21 N5 O3 CCNC(=O)Nc....
26 6F86 ic50 = 0.037 uM CWW C17 H16 Br N7 O2 CCNC(=O)Nc....
27 5Z4O - HX8 C12 H10 O2 c1ccc(cc1)....
28 6F8J ic50 = 0.086 uM CZ5 C17 H17 N7 O2 CCNC(=O)Nc....
29 5MMP ic50 = 0.03 uM G3Z C22 H20 N6 O CCNC(=O)Nc....
30 4DUH Kd = 6.6 uM RLI C17 H16 N4 O3 S2 CCC(=O)Nc1....
31 7C7O ic50 = 0.52 nM FKU C21 H22 F N5 O4 CNc1cc(cc2....
32 7C7N ic50 = 0.36 nM FKR C18 H14 F N3 O4 CNc1cc(cc2....
33 5MMN ic50 = 0.125 uM O54 C19 H20 N4 O CCNC(=O)Nc....
34 6F96 ic50 = 0.019 uM D0K C21 H22 N6 O3 CCNC(=O)Nc....
35 5Z9F - AX7 C7 H7 N3 c1ccc2c(c1....
36 6ENH - BHW C55 H59 N5 O20 Cc1ccc([nH....
37 1KIJ - NOV C31 H36 N2 O11 Cc1c(ccc2c....
38 4WUB - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
39 4PRX - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
40 6ENG - BHW C55 H59 N5 O20 Cc1ccc([nH....
41 4XTJ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
42 1EI1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
43 4PU9 - ADP BEF n/a n/a
44 4WUC - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
45 4PRV - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
46 4WUD - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
47 4ZVI Kd = 0.47 uM 4S4 C14 H11 Br2 N3 O4 c1cc(ccc1C....
48 1S16 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
49 4URN - NOV C31 H36 N2 O11 Cc1c(ccc2c....
50 4HY1 Ki = 2 nM 19X C20 H19 Cl N6 O S CCc1c(c2c(....
51 4HYM Ki = 6 nM CJC C19 H19 Cl N8 O S CCc1c(c2c(....
52 4HXW Ki = 2 nM 1A0 C19 H19 Cl N8 S CCc1c(c2c(....
53 4GFN Ki = 5 nM SUY C17 H18 Cl N7 S CCc1c(c2c(....
54 4P8O - 883 C19 H16 F N7 O CCNC(=O)Nc....
55 6Y8N ic50 = 9 nM OGH C21 H21 F N8 O Cc1ncc(cn1....
56 6Y8L - NOV C31 H36 N2 O11 Cc1c(ccc2c....
57 4B6C ic50 = 0.69 uM B5U C27 H34 N6 O2 Cc1ccc(cc1....
58 4LP0 ic50 < 10 nM 1YM C18 H14 F3 N5 O3 S CCNC(=O)Nc....
59 4EMV ic50 = 0.005 uM 0R9 C20 H15 F3 N6 O3 CCNC(=O)c1....
60 4MB9 - 28F C18 H20 N6 O3 S CCNC(=O)Nc....
61 4MBC - 28G C21 H24 N6 O3 S C=CCNC(=O)....
62 4LPB ic50 < 10 nM 1YP C19 H14 F3 N7 O3 S CCNC(=O)Nc....
63 4MOT - 2B7 C20 H23 N5 O2 S CC(C)CCN1c....
64 4EM7 ic50 = 7.7 uM 0RA C16 H14 N2 O2 c1cc(cc(c1....
65 6M1S Ki < 1 nM EZ9 C26 H23 F4 N7 O3 CCNc1cc(cc....
66 6M1J Ki = 2 nM EZ6 C24 H17 F4 N7 O2 CNc1cc(cc2....
67 4BAE ic50 = 3 nM RWX C19 H21 Br Cl N7 O4 S Cc1c(c(c([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 55D; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 55D 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 55D; Similar ligands found: 458
No: Ligand Similarity coefficient
1 C9E 0.9364
2 ZME 0.9310
3 6Q3 0.9287
4 F12 0.9266
5 CIY 0.9265
6 BK9 0.9255
7 7I2 0.9247
8 1QP 0.9242
9 CKU 0.9242
10 E35 0.9226
11 2KU 0.9215
12 O2Y 0.9208
13 ZIP 0.9202
14 N7I 0.9202
15 4Z3 0.9200
16 OSB 0.9186
17 QUB 0.9180
18 FER 0.9171
19 GJK 0.9170
20 EGR 0.9168
21 L21 0.9166
22 BDI 0.9164
23 4A1 0.9153
24 C9M 0.9151
25 B21 0.9151
26 5WT 0.9151
27 5F8 0.9131
28 67Y 0.9125
29 VM1 0.9123
30 Q5M 0.9119
31 8G6 0.9116
32 XFE 0.9116
33 A5H 0.9114
34 BPU 0.9108
35 FUZ 0.9106
36 61M 0.9106
37 JR2 0.9102
38 XQI 0.9093
39 692 0.9092
40 1XF 0.9088
41 92P 0.9087
42 H7Y 0.9084
43 ONZ 0.9083
44 G6P 0.9082
45 JP2 0.9077
46 LL1 0.9072
47 3Y7 0.9065
48 IOP 0.9065
49 6XI 0.9064
50 2V0 0.9060
51 BZE 0.9058
52 M4E 0.9051
53 M02 0.9046
54 4V2 0.9045
55 8NX 0.9045
56 EWG 0.9041
57 VXX 0.9035
58 FF2 0.9034
59 HBO 0.9032
60 ZEA 0.9032
61 3EB 0.9031
62 5OF 0.9030
63 H4E 0.9029
64 PH2 0.9029
65 DXK 0.9028
66 SQP 0.9023
67 KTW 0.9018
68 ALE 0.9016
69 XDE 0.9016
70 XEN 0.9013
71 GOE 0.9010
72 9F8 0.9008
73 64E 0.9008
74 ZHA 0.9007
75 5F5 0.9003
76 CKA 0.9003
77 S8D 0.9000
78 GV9 0.8996
79 7MX 0.8993
80 ZYV 0.8992
81 5FL 0.8991
82 878 0.8990
83 ZZ8 0.8989
84 1X8 0.8989
85 C2Y 0.8989
86 X0W 0.8988
87 HPT 0.8987
88 3D8 0.8986
89 V1T 0.8984
90 ITE 0.8980
91 SRO 0.8978
92 QMS 0.8977
93 AUY 0.8975
94 H35 0.8975
95 6HP 0.8974
96 1A7 0.8973
97 WA2 0.8971
98 2LY 0.8969
99 L22 0.8967
100 4XF 0.8966
101 MBP 0.8966
102 MXD 0.8965
103 R20 0.8965
104 TRP 0.8961
105 F2W 0.8960
106 4ME 0.8960
107 9GP 0.8960
108 28S 0.8958
109 4XY 0.8957
110 JND 0.8956
111 ELH 0.8953
112 TSS 0.8946
113 I2E 0.8945
114 TXW 0.8943
115 CR1 0.8938
116 774 0.8936
117 64C 0.8936
118 FCD 0.8932
119 SNY 0.8929
120 1Z8 0.8929
121 8IG 0.8928
122 K3Q 0.8923
123 AC2 0.8923
124 AMR 0.8918
125 N8Y 0.8914
126 6ME 0.8914
127 ESI 0.8913
128 PRZ 0.8911
129 CCV 0.8910
130 0LO 0.8907
131 3IB 0.8907
132 P83 0.8905
133 NFZ 0.8905
134 EYA 0.8904
135 64F 0.8903
136 4R1 0.8899
137 YE7 0.8899
138 BG6 0.8899
139 0XT 0.8895
140 AH9 0.8894
141 0FK 0.8893
142 CX4 0.8891
143 HA5 0.8889
144 AEH 0.8889
145 8TX 0.8888
146 GO2 0.8888
147 6J9 0.8887
148 HHR 0.8887
149 2JK 0.8886
150 EV0 0.8885
151 UFO 0.8884
152 7M6 0.8883
153 M3Q 0.8883
154 M1Z 0.8882
155 GO8 0.8882
156 ENO 0.8882
157 5WU 0.8881
158 X3J 0.8880
159 ZYQ 0.8878
160 P7Y 0.8877
161 54X 0.8871
162 6DP 0.8870
163 5TZ 0.8868
164 7ME 0.8868
165 15A 0.8867
166 W8G 0.8866
167 P4L 0.8865
168 28N 0.8864
169 AY4 0.8863
170 AX3 0.8862
171 M01 0.8861
172 QBS 0.8860
173 FC2 0.8858
174 CXH 0.8856
175 EYM 0.8855
176 B55 0.8850
177 AIN 0.8849
178 DNF 0.8849
179 NAG 0.8847
180 ASC 0.8844
181 YTX 0.8844
182 C0W 0.8841
183 X11 0.8841
184 MUX 0.8840
185 R4E 0.8840
186 3RI 0.8840
187 C09 0.8838
188 78P 0.8837
189 NBG 0.8837
190 EOL 0.8835
191 MUR 0.8835
192 5V7 0.8835
193 4I8 0.8835
194 DNC 0.8831
195 EYY 0.8830
196 N2I 0.8829
197 CFA 0.8827
198 DHC 0.8824
199 0W1 0.8824
200 HL4 0.8823
201 L5V 0.8822
202 3TC 0.8822
203 M3E 0.8822
204 D8Q 0.8821
205 P9I 0.8821
206 MD6 0.8819
207 5WM 0.8818
208 HRM 0.8816
209 2B4 0.8815
210 5WS 0.8815
211 QR2 0.8815
212 HA6 0.8815
213 NBV 0.8815
214 JAA 0.8814
215 B23 0.8813
216 DTR 0.8812
217 8UY 0.8812
218 F5C 0.8812
219 8NB 0.8810
220 GB4 0.8810
221 SG2 0.8808
222 3R6 0.8806
223 MPP 0.8805
224 6TZ 0.8804
225 LAH 0.8804
226 1FE 0.8803
227 LEL 0.8802
228 GZ2 0.8801
229 BPY 0.8801
230 YE6 0.8801
231 9BF 0.8801
232 2K8 0.8800
233 6PB 0.8796
234 30G 0.8795
235 WUB 0.8794
236 OW7 0.8794
237 ONR 0.8792
238 4A5 0.8788
239 PLP 0.8786
240 PXP 0.8786
241 1QV 0.8785
242 A29 0.8785
243 E7S 0.8783
244 GNV 0.8783
245 0RY 0.8782
246 OX2 0.8780
247 SQM 0.8780
248 14W 0.8778
249 S60 0.8777
250 JTA 0.8776
251 KLV 0.8775
252 D80 0.8774
253 B4O 0.8773
254 2UD 0.8773
255 1X7 0.8772
256 XAZ 0.8772
257 8WT 0.8770
258 M6P 0.8770
259 V2Z 0.8770
260 TWO 0.8768
261 SQ7 0.8767
262 5E4 0.8767
263 68A 0.8766
264 8W9 0.8765
265 5WN 0.8762
266 LTN 0.8761
267 9UL 0.8761
268 EN1 0.8759
269 TSR 0.8759
270 15E 0.8758
271 7ZL 0.8757
272 293 0.8757
273 LSQ 0.8756
274 QIV 0.8756
275 AS3 0.8756
276 SYR 0.8755
277 EVO 0.8755
278 45L 0.8754
279 9OF 0.8754
280 7FF 0.8753
281 3IL 0.8753
282 KDV 0.8750
283 8XQ 0.8749
284 BGU 0.8748
285 5JT 0.8746
286 GVI 0.8746
287 SQ4 0.8745
288 2HC 0.8744
289 4MU 0.8740
290 X8Z 0.8739
291 DEE 0.8738
292 4NO 0.8737
293 MCO 0.8732
294 HH6 0.8730
295 SXX 0.8730
296 K37 0.8729
297 RVE 0.8729
298 AH3 0.8725
299 4ZF 0.8725
300 0LH 0.8724
301 5XW 0.8724
302 IQ5 0.8724
303 3D3 0.8722
304 TCR 0.8722
305 6ZW 0.8722
306 DAH 0.8721
307 2D3 0.8717
308 5P3 0.8715
309 TB8 0.8714
310 R2P 0.8713
311 6L6 0.8712
312 K3Y 0.8712
313 EQA 0.8711
314 R9Y 0.8711
315 L99 0.8710
316 4AV 0.8710
317 0FO 0.8709
318 GHM 0.8707
319 C4L 0.8705
320 D2G 0.8705
321 B2J 0.8704
322 NDG 0.8704
323 CK2 0.8703
324 N2M 0.8700
325 ZRL 0.8700
326 AJD 0.8699
327 8HC 0.8698
328 MLZ 0.8698
329 2LX 0.8697
330 NCV 0.8697
331 0M9 0.8695
332 209 0.8694
333 XG1 0.8693
334 IPT 0.8693
335 3VX 0.8692
336 BY5 0.8691
337 TLF 0.8691
338 ILE VAL 0.8691
339 S98 0.8690
340 DK1 0.8690
341 0SY 0.8689
342 0NX 0.8686
343 GNY 0.8685
344 H33 0.8685
345 LDP 0.8683
346 X0T 0.8682
347 SLC 0.8682
348 M78 0.8680
349 M3P 0.8676
350 X0U 0.8675
351 AKD 0.8675
352 EMZ 0.8674
353 PMP 0.8673
354 FUD 0.8671
355 AM1 0.8670
356 NIG 0.8670
357 344 0.8669
358 BB4 0.8668
359 NFM 0.8667
360 3Z8 0.8667
361 K25 0.8667
362 2WU 0.8666
363 OMD 0.8665
364 YEX 0.8664
365 RD4 0.8664
366 MFZ 0.8663
367 7MU 0.8661
368 1Z6 0.8661
369 APZ 0.8660
370 FSU 0.8657
371 LDR 0.8656
372 42C 0.8655
373 289 0.8655
374 49P 0.8655
375 HNQ 0.8654
376 GLP 0.8654
377 069 0.8653
378 XQK 0.8651
379 TZM 0.8650
380 GI3 0.8648
381 H4B 0.8648
382 EYV 0.8645
383 HHS 0.8644
384 M6D 0.8643
385 KJU 0.8643
386 1AJ 0.8642
387 NPL 0.8639
388 2FQ 0.8639
389 D3G 0.8638
390 36M 0.8637
391 C4E 0.8635
392 AJY 0.8635
393 AKH 0.8635
394 795 0.8634
395 ANC 0.8631
396 A4V 0.8629
397 ZYR 0.8628
398 ID8 0.8624
399 LNR 0.8622
400 ZRK 0.8621
401 JF1 0.8620
402 N91 0.8619
403 22L 0.8619
404 9AP 0.8617
405 D87 0.8615
406 RZH 0.8615
407 3XH 0.8614
408 QZ8 0.8614
409 4MX 0.8608
410 DEW 0.8606
411 R9G 0.8605
412 KUF 0.8603
413 5E5 0.8602
414 MRW 0.8598
415 GT1 0.8598
416 VYM 0.8597
417 M6Z 0.8595
418 GNJ 0.8595
419 TIZ 0.8595
420 JYB 0.8594
421 MVN 0.8593
422 RB2 0.8591
423 IBM 0.8588
424 EMU 0.8585
425 FWB 0.8582
426 27M 0.8582
427 BGP 0.8581
428 ARG 0.8580
429 GZL 0.8579
430 KG1 0.8578
431 MPK 0.8576
432 4FE 0.8569
433 5GU 0.8569
434 HBI 0.8568
435 AVA 0.8568
436 B2E 0.8566
437 SJK 0.8565
438 7L4 0.8563
439 A7K 0.8563
440 JF2 0.8559
441 25O 0.8553
442 SSM 0.8550
443 SZ7 0.8546
444 KCH 0.8546
445 5TY 0.8544
446 JG8 0.8542
447 XDK 0.8541
448 RJY 0.8539
449 CIR 0.8529
450 MYI 0.8526
451 QX4 0.8525
452 EXL 0.8524
453 K2P 0.8523
454 TIA 0.8523
455 HX4 0.8515
456 BCU 0.8513
457 GCO 0.8513
458 P1J 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3TTZ; Ligand: 07N; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3ttz.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 3TTZ; Ligand: 07N; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 3ttz.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
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