Receptor
PDB id Resolution Class Description Source Keywords
5CKW 2.49 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEGK4_AMPPNP KINASE LEGIONELLA PNEUMOPHILA (STRAIN LENS) LEGIONELLA BACTERIAL EFFECTORS SERINE/THREONINE KINASE TYSECRETION SYSTEM TRANSFERASE
Ref.: THE STRUCTURE OF LEGIONELLA PNEUMOPHILA LEGK4 TYPE SECRETION SYSTEM (T4SS) EFFECTOR REVEALS A NOVEL DI EUKARYOTIC-LIKE KINASE. SCI REP V. 5 14602 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:504;
B:504;
Part of Protein;
Invalid;
none;
none;
submit data
40.078 Ca [Ca+2...
MG A:502;
B:502;
B:503;
A:503;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP A:501;
B:501;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5CKW 2.49 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEGK4_AMPPNP KINASE LEGIONELLA PNEUMOPHILA (STRAIN LENS) LEGIONELLA BACTERIAL EFFECTORS SERINE/THREONINE KINASE TYSECRETION SYSTEM TRANSFERASE
Ref.: THE STRUCTURE OF LEGIONELLA PNEUMOPHILA LEGK4 TYPE SECRETION SYSTEM (T4SS) EFFECTOR REVEALS A NOVEL DI EUKARYOTIC-LIKE KINASE. SCI REP V. 5 14602 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5CKW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5CKW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 5CKW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5CKW; Ligand: ANP; Similar sites found: 291
This union binding pocket(no: 1) in the query (biounit: 5ckw.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3V4S ATP 0.0003291 0.41577 1.55039
2 5GZ9 ANP 0.0001957 0.50082 1.96721
3 2PUL ACP 0.00001334 0.50121 2.01511
4 1IA9 ANP 0.0002531 0.43732 2.14286
5 3MGB GHP 3MY 3FG GHP GHP OMY 3FG 0.008154 0.41801 2.19436
6 5NCY 8TK 0.00006212 0.40341 2.21729
7 3K5I ADP 0.0008527 0.41471 2.23325
8 4GYI ADP 0.0000007018 0.57892 2.267
9 2Q7D ANP 0.00009233 0.41402 2.31214
10 2CIR BG6 0.01233 0.40873 2.3569
11 2PYW ADP 0.00000006896 0.54913 2.38095
12 2E5A LAQ 0.02225 0.40701 2.59366
13 4OCJ NDG 0.00005817 0.54915 2.63852
14 4YNU LGC 0.04949 0.40778 2.66075
15 4CYI ATP 0.00007697 0.51619 2.73973
16 2IF8 ADP 0.000146 0.50065 2.75482
17 1M0W ANP 0.0003731 0.47346 2.88248
18 1T36 ADP 0.004872 0.43876 2.88248
19 3VSV XYS 0.01308 0.40954 2.88248
20 3VP6 HLD 0.017 0.40879 2.88248
21 4OCV ANP 0.00001315 0.48648 2.90237
22 1I7M PUT 0.008607 0.40441 2.99625
23 3ETH ATP 0.0007542 0.4702 3.10421
24 2QK4 ATP 0.0003586 0.46292 3.10421
25 5FI4 5XV 0.003134 0.44356 3.10421
26 4UWH JXM 0.0002306 0.45994 3.1614
27 3AKK ADP 0.0002213 0.43639 3.38462
28 4LH7 1X8 0.01271 0.4033 3.40557
29 2AQX ATP 0.0004983 0.40935 3.46021
30 4ZS4 ATP 0.0003076 0.43304 3.58306
31 5USZ SKE 0.00001195 0.43349 3.80623
32 3X01 AMP 0.000005163 0.57726 3.81679
33 5IGI GMP 0.000109 0.53375 3.99113
34 5IGI ZIT 0.0001159 0.53375 3.99113
35 3PDT ADP 0.0003597 0.45214 4
36 4CC6 L5Y 0.008208 0.4097 4.08805
37 2PVF ACP 0.000009351 0.50838 4.19162
38 3UDZ ADP 0.0002831 0.48655 4.21286
39 3NW7 LGV 0.001342 0.4867 4.23453
40 5KO1 6UY 0.00003794 0.48355 4.24028
41 5C1P ADP 0.0009033 0.44193 4.24837
42 3HAV ATP 0.00009716 0.51264 4.34783
43 3I0O ADP 0.000007191 0.54781 4.42478
44 2YRX AMP 0.00005666 0.52651 4.43459
45 3RI1 3RH 0.00003008 0.54696 4.47284
46 3W0O ADP 0.000002834 0.43751 4.58453
47 3W0O HY0 0.000002834 0.43751 4.58453
48 1XZ3 ICF 0.007632 0.40995 4.5977
49 5ML3 DL3 0.04427 0.40045 4.69799
50 3P7G MAN 0.0132 0.40579 4.79452
51 3VPC ADP 0.0001676 0.42448 4.96454
52 5IQD RIO 0.000009702 0.58916 5.2459
53 5IQD GNP 0.00000905 0.58916 5.2459
54 4O1P ANP 0.0000337 0.52847 5.32151
55 3VPB ADP 0.00002903 0.43048 5.35714
56 3VOT ADP 0.00001193 0.53756 5.41176
57 3TPV ADE 0.0005896 0.42531 5.68182
58 4OAV ACP 0.00003107 0.48739 5.76497
59 4YLL 4E3 0.00006415 0.52453 5.81717
60 5AWM ANP 0.00003479 0.5159 5.83756
61 5MW8 ATP 0.00003884 0.5352 5.9867
62 5VZ0 ADP 0.0008432 0.45916 5.9867
63 4IZY 1J2 0.0001451 0.43444 6.23306
64 2D6M LBT 0.009544 0.41108 6.28931
65 2HK5 1BM 0.0000414 0.52924 6.2963
66 4UX9 ANP 0.00002426 0.46921 6.31868
67 4I94 ANP 0.00001102 0.54884 6.33333
68 3PTG 932 0.0005732 0.45244 6.33609
69 5C03 AGS 0.00004433 0.46829 6.65188
70 4WOV 3SM 0.0007306 0.44559 6.65188
71 3IES M24 0.0234 0.41287 6.65188
72 4AU8 Z3R 0.0001329 0.48877 6.75676
73 4K33 ACP 0.00003463 0.53051 6.76923
74 5MY8 RXZ 0.00003922 0.42809 6.78851
75 1CBK ROI 0.002701 0.4397 6.875
76 5UR1 YY9 0.0006136 0.50126 7.07396
77 5JKG 6LF 0.002386 0.46616 7.07396
78 4LRJ ANP 0.0002923 0.45085 7.10059
79 1UNH IXM 0.00007799 0.48992 7.21154
80 4JR7 GNP 0.000000515 0.54548 7.48663
81 4OUC 5ID 0.0001207 0.47329 8.12325
82 3HZT J60 0.00001583 0.53184 8.20399
83 2X2M X2M 0.0002742 0.4916 8.28025
84 3M2W L8I 0.000006046 0.55482 8.3612
85 4IDT T28 0.00001421 0.50211 8.42697
86 3PE2 E1B 0.000003493 0.62222 8.60534
87 5TDF ADP 0.0001479 0.50245 8.64198
88 3IGO ANP 0.00003249 0.45443 8.64745
89 1W2D ADP 0.0003064 0.47186 8.67924
90 4OH4 ANP 0.000007744 0.49878 8.70871
91 5DMZ ADP 0.000007057 0.50193 8.76712
92 3GC0 AMP 0.00007051 0.4905 8.81459
93 1TQP ATP 0.0000003447 0.49462 8.86525
94 4AZT LY2 0.00003064 0.51847 8.86918
95 3PP0 03Q 0.00002526 0.43 8.87574
96 5T8O 76Z 0.00001303 0.479 8.88252
97 1XJD STU 0.0000001434 0.55137 8.98551
98 1V0O INR 0.00005023 0.46323 9.02778
99 1TZD ADP 0.00002331 0.54217 9.09091
100 4XYM A12 0.0002344 0.43664 9.13043
101 4Y93 746 0.0001365 0.41601 9.19283
102 5I35 ANP 0.000002516 0.53126 9.41476
103 3BU5 ATP 0.000008797 0.55641 9.47712
104 5UIU 8CG 0.0001986 0.51145 9.59752
105 1JPA ANP 0.000002314 0.61751 9.61539
106 3C0G 3AM 0.00002243 0.51247 9.68661
107 1K3A ACP 0.0002226 0.46799 9.699
108 5W2I I3P 0.000263 0.41077 9.72763
109 5W2I ADP 0.000263 0.41077 9.72763
110 2QX0 PH2 0.001743 0.44687 10.0629
111 3O0G 3O0 0.00000137 0.59194 10.0671
112 1ZTH ADP 0.0000008641 0.5907 10.0775
113 1ZP9 ATP 0.000002165 0.54457 10.0775
114 2WEL K88 0.0005283 0.43496 10.0917
115 4WNK 453 0.000003066 0.4365 10.1996
116 2VPQ ANP 0.00443 0.43447 10.1996
117 2JLD AG1 0.00002042 0.40617 10.2381
118 3Q60 ATP 0.001295 0.41917 10.2426
119 4F9C 0SX 0.000006966 0.55832 10.2493
120 2V7O DRN 0.000001115 0.57497 10.4167
121 4DC2 ADE 0.000007446 0.49529 10.4213
122 2PVN P63 0.00000284 0.44533 10.5114
123 3MVH WFE 0.000001639 0.61609 10.5263
124 2RIO ADP 0.0001616 0.49332 10.5991
125 4L9I 8PR 0.00243 0.41298 10.643
126 4R78 AMP 0.00003594 0.52266 10.6796
127 4G17 0VN 0.00001247 0.54326 10.9091
128 2VN9 GVD 0.00001138 0.52868 10.9635
129 2BKK ADP 0.000006703 0.53594 10.9848
130 3TM0 ANP 0.00001535 0.40677 11.0266
131 3TM0 B31 0.00001658 0.40119 11.0266
132 4FL3 ANP 0.00004555 0.4507 11.0865
133 4WB7 ATP 0.00000331 0.40798 11.1111
134 3TKI S25 0.000008201 0.61007 11.4551
135 3V8S 0HD 0.0000106 0.50373 11.4634
136 2HY0 306 0.0003596 0.45892 11.4907
137 4YMJ 4EJ 0.00008487 0.51691 11.5132
138 2H8H H8H 0.000004898 0.51064 11.5299
139 4U98 ACP 0.0000217 0.4941 11.5299
140 1Y57 MPZ 0.000002455 0.4781 11.5299
141 3ZRM ZRM 0.00001211 0.54975 11.5903
142 4EUU BX7 0.00001758 0.43713 11.5987
143 5EKO N17 0.002786 0.44435 11.8598
144 3LXN MI1 0.0000005842 0.51769 11.9497
145 4EWH T77 0.0000008333 0.4613 12
146 3RE4 TO1 0.000003384 0.56307 12.0155
147 2CSN CKI 0.01622 0.43755 12.1212
148 2YAB AMP 0.000001294 0.51866 12.1884
149 3F7Z 34O 0.000003111 0.57802 12.2857
150 1U5R ATP 0.00001475 0.49036 12.3563
151 5LI1 ANP 0.000001485 0.60197 12.4294
152 4L3L 5FI 0.000005588 0.58934 12.5
153 2YW2 ATP 0.0003459 0.42241 12.5
154 5IH9 6BF 0.00002563 0.56446 12.5373
155 4CFU 2WC 0.000003551 0.53498 12.5413
156 4WB6 ATP 0.000001232 0.61582 12.5714
157 5LI9 ACP 0.00003366 0.46559 12.5714
158 3UIM ANP 0.00001224 0.49015 12.5767
159 4GJ3 0XP 0.000001353 0.43595 12.5828
160 2WU6 DKI 0.00000125 0.48757 12.5984
161 4BCQ TJF 0.00002968 0.51912 12.6246
162 4BCM T7Z 0.0001536 0.49956 12.6246
163 4QTB 38Z 0.0001556 0.51508 12.6316
164 2YAK OSV 0.000002869 0.44244 12.6316
165 4BCN T9N 0.00000221 0.55686 12.6667
166 3AQV TAK 0.0002644 0.48562 12.6812
167 4E1Z 0MX 0.000002806 0.47671 12.7148
168 2XK9 XK9 0.04183 0.42443 12.7329
169 2XMY CDK 0.00008317 0.56591 12.7517
170 5LMK 6ZK 0.003524 0.42732 12.7946
171 4YZC STU 0.00001903 0.57261 12.8395
172 1RE8 BD2 0.000003981 0.61925 12.8571
173 2QCS ANP 0.000001771 0.60799 12.8571
174 3FHI ANP 0.000002435 0.60113 12.8571
175 3IDB ANP 0.0000009251 0.4944 12.8571
176 4BFM ANP 0.000001996 0.50497 12.8743
177 5W4W 9WG 0.0000179 0.44324 12.9909
178 4KBA 1QM 0.00008985 0.4019 12.9909
179 1PHK ATP 0.00001212 0.55247 13.0872
180 4X7Q 3YR 0.000003132 0.51536 13.141
181 3OFM 4B0 0.00002096 0.52947 13.1429
182 4H3Q ANP 0.00009641 0.51587 13.2597
183 4H3P ANP 0.00005917 0.46982 13.2597
184 3CY2 MB9 0.0000009978 0.4923 13.3758
185 4Y85 499 0.0002446 0.45306 13.5542
186 5X8I SQZ 0.000005766 0.50626 13.5838
187 2WEI VGG 0.0008719 0.43515 13.5889
188 3H9R TAK 0.0006223 0.46339 13.6364
189 2R5T ANP 0.000008145 0.47274 13.6729
190 2PZI AXX 0.0005022 0.45429 13.7472
191 3LXK MI1 0.000003947 0.44312 13.7615
192 4BHN BH9 0.000001897 0.50177 13.7725
193 3GQI ACP 0.0000225 0.48355 13.8037
194 5EFQ ADP 0.00001857 0.48471 13.8329
195 3KRR DQX 0.000006628 0.62451 13.8983
196 3GGF GVD 0.00000146 0.5513 13.9535
197 3FHR P4O 0.0001516 0.4446 14.2857
198 5MJA 7O3 0.0005368 0.46599 14.4262
199 4Q5H ANP 0.00000004625 0.58079 14.4737
200 3SLS ANP 0.0003423 0.422 14.4737
201 4AUA 4AU 0.0002418 0.45038 14.658
202 5FBN 5WF 0.0004249 0.50075 14.7601
203 3ORK AGS 0.00006318 0.43195 14.791
204 3ALN ANP 0.0001567 0.43531 14.9847
205 4M69 ANP 0.0003985 0.42275 15.016
206 5HQ0 LZ9 0.000008499 0.47904 15.2318
207 4N70 2HX 0.000003398 0.62549 15.2439
208 4U44 3D9 0.000009755 0.55426 15.3614
209 3KN5 ANP 0.00006405 0.50669 15.3846
210 4E93 GUI 0.00001409 0.40709 15.3846
211 5A6N U7E 0.000001777 0.59264 15.5477
212 1Q8Y ADP 0.00002291 0.54169 15.5496
213 1Q8Y ADE 0.00006293 0.49611 15.5496
214 1OUK 084 0.001006 0.52545 15.5738
215 4LOO SB4 0.001579 0.44843 15.7895
216 4OTH DRN 0.00000155 0.4973 15.8358
217 4I6H 1C8 0.000358 0.42858 15.9091
218 5HES 032 0.0001607 0.50291 15.9609
219 3TXO 07U 0.00000194 0.58147 16.1473
220 4Y8D 49J 0.00004838 0.46827 16.1765
221 3DAK ANP 0.000003173 0.53775 16.2069
222 2VZ6 FEF 0.000006677 0.53447 16.2939
223 5EOB 5QQ 0.0005413 0.51425 16.3009
224 1CM8 ANP 0.00001998 0.53654 16.3488
225 3GC8 B45 0.00001351 0.46178 16.4865
226 5JZJ AN2 0.00001887 0.4967 16.4983
227 5HX8 66P 0.0000007355 0.46862 16.5563
228 5UOX 8GY 0.000002912 0.48724 16.6052
229 2F57 23D 0.0002867 0.45629 16.7192
230 4YZN 4K5 0.000000965 0.4943 16.7247
231 5U6C 7YS 0.000005023 0.47809 16.8254
232 1ZY5 ANP 0.0002347 0.48561 17.1617
233 5AX9 4KT 0.000009652 0.49695 17.2078
234 5VC5 96M 0.00007417 0.52938 17.301
235 4C2W ANP 0.001852 0.43542 17.3077
236 3DLS ADP 0.0000003581 0.61617 17.3134
237 4FG8 ATP 0.000003423 0.58168 17.4603
238 5CEO 50D 0.0006411 0.4672 17.6667
239 3SRV S19 0.000001291 0.59317 18.0505
240 2Y6O 1N1 0.0002598 0.41683 18.2131
241 4F4P 0SB 0.00003563 0.58123 18.315
242 4WNP 3RJ 0.000003717 0.54887 18.4669
243 3G5D 1N1 0.000008025 0.61281 18.5315
244 2ZV2 609 0.000006077 0.55122 19.1275
245 2B9F ADP 0.00004157 0.5241 19.2635
246 5G1X ADP 0.0001032 0.46934 19.2982
247 5L8L ADP 0.0004011 0.46641 19.2982
248 5LXM ADP 0.000023 0.49253 19.4346
249 5H2U 1N1 0.000717 0.42392 19.4757
250 1U59 STU 0.0000005932 0.54161 19.5122
251 3GNI ATP 0.00003402 0.45997 19.5373
252 2B9H ADP 0.00005738 0.51994 19.5467
253 2B9J ADP 0.00002594 0.49006 19.5467
254 2B9I ADP 0.00003275 0.47771 19.5467
255 5DA3 58V 0.0005763 0.45907 19.6226
256 4NFN 2KC 0.000005022 0.51252 20.0647
257 3PLS ANP 0.000007563 0.51163 20.1342
258 3E5A VX6 0.00006496 0.42127 20.5224
259 2QLU ADE 0.0006302 0.48405 20.7006
260 4NM5 ADP 0.0000141 0.46007 20.8333
261 4JDI ANP 0.00003072 0.46042 21.0983
262 4KS7 X4Z 0.0001407 0.42271 21.2329
263 4NW6 2NS 0.000004574 0.42275 21.3622
264 2XVD AS6 0.00001849 0.41878 22.1854
265 4Y0X ADP 0.0000001216 0.59714 22.4
266 3KMW ATP 0.0002106 0.45275 22.4806
267 4CLI 5P8 0.00005065 0.55889 22.9358
268 4NST ADP 0.00001462 0.48879 23.0769
269 5M06 ADP 0.0004448 0.44457 23.1884
270 5UKL SIX 0.0002765 0.5009 23.2816
271 3PVW QRX 0.00001803 0.43409 23.2816
272 4IJP 1EH 0.0000376 0.53126 24.3017
273 4BTK DTQ 0.00000419 0.57183 24.6291
274 5JFS 6K0 0.00006245 0.5503 24.6753
275 5LVP ATP 0.000177 0.48595 25.0804
276 2Z7R STU 0.000001893 0.49795 26.4798
277 4XV1 904 0.000008451 0.58574 27.3973
278 5HVJ ANP 0.0004266 0.47647 27.619
279 5VCV 1N1 0.000004031 0.46737 27.6527
280 4CQE CQE 0.000003092 0.48399 27.6978
281 5DH3 5BS 0.00007969 0.44841 28.254
282 4USF 6UI 0.0001714 0.50566 28.6184
283 2WQN ADP 0.001638 0.42899 29.0323
284 1BYG STU 0.000004868 0.52734 29.1367
285 2A19 ANP 0.0000004624 0.60336 29.5775
286 3SXS PP2 0.0002295 0.42667 30.2239
287 3HMO STU 0.00071 0.43102 30.7018
288 4CSV STI 0.0002983 0.40648 31.6364
289 4A4X JUP 0.00004908 0.42118 33.3333
290 4XLI 1N1 0.00005108 0.47557 33.9552
291 4D2S DYK 0.002182 0.42513 37.3239
Pocket No.: 2; Query (leader) PDB : 5CKW; Ligand: ANP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5ckw.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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