Receptor
PDB id Resolution Class Description Source Keywords
5CEW 2.03 Å EC: 2.3.3.9 CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTH COMPLEX WITH 2-(PYRIDIN-4-YL)THIAZOLIDINE-4-CARBOXYLIC ACID MYCOBACTERIUM TUBERCULOSIS (STRAIN ATCH37RV) COMPLEX FRAGMENT INHIBITOR TRANSFERASE-TRANSFERASE INHIBICOMPLEX
Ref.: MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE STRUCTUR FRAGMENTS REVEAL A PORTAL FOR SUBSTRATE/PRODUCT EXC J. BIOL. CHEM. V. 291 27421 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
6MW A:802;
 Valid;
 none;
 submit data
210.253 C9 H10 N2 O2 S c1cnc...
MG A:801;
 Part of Protein;
 none;
 submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6C6O 2.3 Å EC: 2.3.3.9 CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTH COMPLEX WITH 2-BR-4-OH-PHENYLDIKETOACID MYCOBACTERIUM TUBERCULOSIS ACETYLTRANSFERASE STRUCTURAL GENOMICS TB STRUCTURAL GENOMICONSORTIUM TBSGC TRANSFERASE TRANSFERASE-TRANSFERASE INHCOMPLEX
Ref.: ANION-PI INTERACTIONS IN COMPUTER-AIDED DRUG DESIGN MODELING THE INHIBITION OF MALATE SYNTHASE BY PHENY ACIDS. J CHEM INF MODEL V. 58 2085 2018
Members (34)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 6BU1 ic50 = 0.06 uM E9S C10 H7 Br O5 c1cc(c(c(c....
2 5C9W - 4Z3 C8 H7 Br N2 O2 c1ccc(c(c1....
3 6C8P ic50 = 0.2 uM EQA C10 H7 F O4 c1ccc(c(c1....
4 5DRC - 5ER C12 H9 N O4 c1ccc2c(c1....
5 5DX7 - 5H6 C8 H4 Cl N O3 S c1cc(sc1c2....
6 5ECV - 5M2 C13 H11 N O4 Cc1c2cc[nH....
7 5CBB - 4ZF C12 H9 N3 O2 c1ccc2c(c1....
8 5C7V - PYC C5 H4 N O2 c1cc([nH]c....
9 2GQ3 - MLT C4 H6 O5 C([C@H](C(....
10 5E9X - 5LA C7 H4 Cl N O2 S c1c2cc(sc2....
11 5C9U - 4Z1 C8 H6 Cl2 N2 O3 c1cc(c(cc1....
12 6BA7 ic50 = 0.007 uM D1Y C10 H7 Cl O5 c1cc(c(cc1....
13 5CBI - 4ZC C7 H4 Cl N O c1cc(c(cc1....
14 1N8I - GLV C2 H2 O3 C(=O)C(=O)....
15 5C9R - 4YZ C9 H9 Cl O2 S c1cc(ccc1S....
16 5CBJ - 4ZD C9 H8 O2 S c1ccc(cc1)....
17 5CAH - 4ZA C7 H5 N O2 S c1csc2c1cc....
18 5C9X - 4Z4 C7 H3 Cl2 F O2 c1c(c(cc(c....
19 6AS6 ic50 = 15.2 uM BSV C14 H14 O4 Cc1ccc(cc1....
20 5CJN - 52F C11 H10 N2 O3 c1ccc2c(c1....
21 6DNP ic50 = 6.6 uM GZV C11 H8 F2 O4 Cc1ccc(c(c....
22 5CCZ - 50C C10 H10 F N3 Cc1c(n[nH]....
23 6DKO ic50 = 1.6 uM GXG C10 H6 F2 O4 c1cc(c(c(c....
24 6C6O ic50 = 0.005 uM ENG C10 H7 Br O5 c1cc(c(cc1....
25 6APZ ic50 = 0.15 uM BQ4 C10 H8 O5 c1cc(cc(c1....
26 6AXB ic50 = 0.5 uM C0V C14 H10 O4 c1ccc2cc(c....
27 6C7B ic50 = 1.5 uM ENY C15 H12 O5 COc1ccc2cc....
28 5CEW - 6MW C9 H10 N2 O2 S c1cnccc1[C....
29 5CAK - 4Z9 C11 H11 N O3 c1ccc2c(c1....
30 6ASU ic50 = 6.1 uM BVS C11 H10 O4 Cc1ccc(cc1....
31 6AU9 ic50 = 1.1 uM BXS C12 H10 O6 c1cc2c(cc1....
32 5CJM - 4WL C7 H5 N O2 S c1csc2c1[n....
33 6DL9 ic50 = 1 uM GXD C10 H6 Cl2 O4 c1cc(c(c(c....
34 5T8G - 4Z0 C9 H6 O5 S c1cc(sc1)C....
70% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 6BU1 ic50 = 0.06 uM E9S C10 H7 Br O5 c1cc(c(c(c....
2 5C9W - 4Z3 C8 H7 Br N2 O2 c1ccc(c(c1....
3 6C8P ic50 = 0.2 uM EQA C10 H7 F O4 c1ccc(c(c1....
4 5DRC - 5ER C12 H9 N O4 c1ccc2c(c1....
5 5DX7 - 5H6 C8 H4 Cl N O3 S c1cc(sc1c2....
6 5ECV - 5M2 C13 H11 N O4 Cc1c2cc[nH....
7 5CBB - 4ZF C12 H9 N3 O2 c1ccc2c(c1....
8 5C7V - PYC C5 H4 N O2 c1cc([nH]c....
9 6C7B ic50 = 1.5 uM ENY C15 H12 O5 COc1ccc2cc....
10 5CEW - 6MW C9 H10 N2 O2 S c1cnccc1[C....
11 5CAK - 4Z9 C11 H11 N O3 c1ccc2c(c1....
12 6ASU ic50 = 6.1 uM BVS C11 H10 O4 Cc1ccc(cc1....
13 6AU9 ic50 = 1.1 uM BXS C12 H10 O6 c1cc2c(cc1....
14 5CJM - 4WL C7 H5 N O2 S c1csc2c1[n....
15 6DL9 ic50 = 1 uM GXD C10 H6 Cl2 O4 c1cc(c(c(c....
16 5T8G - 4Z0 C9 H6 O5 S c1cc(sc1)C....
50% Homology Family (35)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 6BU1 ic50 = 0.06 uM E9S C10 H7 Br O5 c1cc(c(c(c....
2 5C9W - 4Z3 C8 H7 Br N2 O2 c1ccc(c(c1....
3 6C8P ic50 = 0.2 uM EQA C10 H7 F O4 c1ccc(c(c1....
4 5DRC - 5ER C12 H9 N O4 c1ccc2c(c1....
5 5DX7 - 5H6 C8 H4 Cl N O3 S c1cc(sc1c2....
6 5ECV - 5M2 C13 H11 N O4 Cc1c2cc[nH....
7 5CBB - 4ZF C12 H9 N3 O2 c1ccc2c(c1....
8 5C7V - PYC C5 H4 N O2 c1cc([nH]c....
9 2GQ3 - MLT C4 H6 O5 C([C@H](C(....
10 5E9X - 5LA C7 H4 Cl N O2 S c1c2cc(sc2....
11 5C9U - 4Z1 C8 H6 Cl2 N2 O3 c1cc(c(cc1....
12 6BA7 ic50 = 0.007 uM D1Y C10 H7 Cl O5 c1cc(c(cc1....
13 5CBI - 4ZC C7 H4 Cl N O c1cc(c(cc1....
14 1N8I - GLV C2 H2 O3 C(=O)C(=O)....
15 5C9R - 4YZ C9 H9 Cl O2 S c1cc(ccc1S....
16 5CBJ - 4ZD C9 H8 O2 S c1ccc(cc1)....
17 5CAH - 4ZA C7 H5 N O2 S c1csc2c1cc....
18 5C9X - 4Z4 C7 H3 Cl2 F O2 c1c(c(cc(c....
19 6AS6 ic50 = 15.2 uM BSV C14 H14 O4 Cc1ccc(cc1....
20 5CJN - 52F C11 H10 N2 O3 c1ccc2c(c1....
21 6DNP ic50 = 6.6 uM GZV C11 H8 F2 O4 Cc1ccc(c(c....
22 5CCZ - 50C C10 H10 F N3 Cc1c(n[nH]....
23 6DKO ic50 = 1.6 uM GXG C10 H6 F2 O4 c1cc(c(c(c....
24 6C6O ic50 = 0.005 uM ENG C10 H7 Br O5 c1cc(c(cc1....
25 6APZ ic50 = 0.15 uM BQ4 C10 H8 O5 c1cc(cc(c1....
26 6AXB ic50 = 0.5 uM C0V C14 H10 O4 c1ccc2cc(c....
27 6C7B ic50 = 1.5 uM ENY C15 H12 O5 COc1ccc2cc....
28 5CEW - 6MW C9 H10 N2 O2 S c1cnccc1[C....
29 5CAK - 4Z9 C11 H11 N O3 c1ccc2c(c1....
30 6ASU ic50 = 6.1 uM BVS C11 H10 O4 Cc1ccc(cc1....
31 6AU9 ic50 = 1.1 uM BXS C12 H10 O6 c1cc2c(cc1....
32 5CJM - 4WL C7 H5 N O2 S c1csc2c1[n....
33 6DL9 ic50 = 1 uM GXD C10 H6 Cl2 O4 c1cc(c(c(c....
34 5T8G - 4Z0 C9 H6 O5 S c1cc(sc1)C....
35 1D8C - SOR C6 H14 O6 C([C@@H]([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 6MW; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 6MW 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 6MW; Similar ligands found: 687
No: Ligand Similarity coefficient
1 3VQ 0.9784
2 KLE 0.9735
3 PUE 0.9734
4 JMG 0.9725
5 G14 0.9724
6 ODK 0.9722
7 ZZA 0.9713
8 AVA 0.9656
9 XI7 0.9643
10 2D2 0.9608
11 FCD 0.9587
12 0K7 0.9564
13 78Y 0.9548
14 LZ5 0.9542
15 11X 0.9535
16 5TZ 0.9520
17 6FG 0.9511
18 RKV 0.9492
19 5H6 0.9476
20 7O4 0.9471
21 A6W 0.9470
22 795 0.9469
23 VM1 0.9467
24 L1T 0.9466
25 BVS 0.9464
26 1XS 0.9463
27 5F8 0.9462
28 0LO 0.9460
29 TCR 0.9444
30 NK5 0.9443
31 D2G 0.9432
32 0NX 0.9424
33 4FF 0.9421
34 5FL 0.9420
35 A9B 0.9418
36 5F5 0.9409
37 EWG 0.9406
38 2FX 0.9406
39 JCZ 0.9400
40 5E5 0.9400
41 492 0.9392
42 4AU 0.9389
43 YE6 0.9373
44 0UL 0.9373
45 LEL 0.9370
46 RA7 0.9362
47 D3G 0.9358
48 FHV 0.9348
49 MJW 0.9347
50 PIQ 0.9336
51 0ON 0.9332
52 68B 0.9330
53 KLS 0.9324
54 5C1 0.9323
55 BZQ 0.9320
56 EYV 0.9319
57 363 0.9313
58 6C8 0.9312
59 QIV 0.9306
60 U7E 0.9301
61 L03 0.9282
62 49P 0.9282
63 0QA 0.9276
64 FC2 0.9275
65 GO2 0.9269
66 S1D 0.9269
67 JSX 0.9268
68 P93 0.9268
69 D1G 0.9261
70 VBC 0.9260
71 8CC 0.9260
72 C4E 0.9258
73 833 0.9258
74 P7V 0.9257
75 8D6 0.9255
76 Q4G 0.9254
77 IQQ 0.9250
78 A5H 0.9248
79 I2E 0.9247
80 6C5 0.9241
81 LL1 0.9236
82 AUV 0.9232
83 DA3 0.9232
84 EQA 0.9231
85 6C4 0.9231
86 RK4 0.9215
87 MD6 0.9214
88 L5D 0.9209
89 5TO 0.9205
90 TMG 0.9205
91 LFQ 0.9203
92 C82 0.9194
93 37E 0.9194
94 4G2 0.9192
95 L2K 0.9191
96 X6W 0.9189
97 0SY 0.9184
98 PQT 0.9184
99 M4N 0.9180
100 7L4 0.9176
101 2JX 0.9175
102 SB7 0.9174
103 6C9 0.9172
104 28A 0.9171
105 X48 0.9170
106 K48 0.9165
107 LR2 0.9164
108 36M 0.9162
109 3GV 0.9161
110 BIK 0.9153
111 M83 0.9153
112 SOJ 0.9153
113 EYJ 0.9147
114 C0W 0.9146
115 27K 0.9145
116 KMY 0.9143
117 5B2 0.9142
118 3VW 0.9140
119 F40 0.9135
120 Y3L 0.9135
121 TRP 0.9131
122 DAH 0.9130
123 IWT 0.9130
124 XCG 0.9127
125 HRM 0.9127
126 SSY 0.9126
127 GVY 0.9125
128 3D8 0.9124
129 FZM 0.9120
130 2UZ 0.9118
131 9JT 0.9112
132 WVV 0.9110
133 P4L 0.9108
134 B21 0.9108
135 TOH 0.9107
136 S7G 0.9105
137 D9Z 0.9105
138 6FB 0.9104
139 KCH 0.9103
140 TYR 0.9103
141 3C5 0.9098
142 VGS 0.9098
143 AJ1 0.9098
144 A51 0.9097
145 Z70 0.9095
146 1AJ 0.9093
147 1VK 0.9092
148 ENO 0.9087
149 KYN 0.9086
150 L22 0.9085
151 II4 0.9083
152 BSA 0.9079
153 JAH 0.9079
154 848 0.9076
155 GZ2 0.9075
156 1A5 0.9075
157 VFM 0.9074
158 S0A 0.9073
159 5PV 0.9072
160 RSV 0.9071
161 VFG 0.9070
162 1FE 0.9069
163 60L 0.9068
164 LGT 0.9061
165 ERZ 0.9059
166 5VU 0.9059
167 2GQ 0.9059
168 EN1 0.9058
169 EYY 0.9056
170 NFZ 0.9053
171 3VX 0.9053
172 ZHA 0.9052
173 F18 0.9052
174 HH6 0.9049
175 JF5 0.9048
176 47V 0.9047
177 C0H 0.9047
178 8YH 0.9046
179 B1J 0.9046
180 AZM 0.9045
181 2PV 0.9044
182 IPO 0.9044
183 MMS 0.9043
184 A73 0.9043
185 MKN 0.9043
186 U13 0.9043
187 LO1 0.9043
188 LTN 0.9042
189 2J5 0.9041
190 XDK 0.9041
191 M5E 0.9039
192 2P3 0.9037
193 6KT 0.9037
194 F63 0.9033
195 ZRK 0.9033
196 FF2 0.9033
197 BP7 0.9030
198 0OP 0.9030
199 JGB 0.9028
200 E3X 0.9027
201 TJM 0.9027
202 1V1 0.9025
203 4V2 0.9022
204 NAL 0.9022
205 9BF 0.9020
206 0OY 0.9017
207 NKI 0.9017
208 MMJ 0.9015
209 R20 0.9015
210 PRL 0.9014
211 ARG 0.9012
212 9CE 0.9012
213 AMR 0.9012
214 2QU 0.9012
215 DXK 0.9011
216 B41 0.9010
217 1V4 0.9010
218 AOY 0.9010
219 2O8 0.9009
220 LL2 0.9009
221 3IP 0.9008
222 1PS 0.9007
223 N9J 0.9006
224 4ZD 0.9003
225 DFL 0.9003
226 20D 0.9002
227 6DQ 0.9002
228 4HB 0.9000
229 IOP 0.8995
230 4FP 0.8994
231 4I8 0.8993
232 6SD 0.8993
233 BZJ 0.8992
234 X2M 0.8990
235 7VY 0.8990
236 2PK 0.8987
237 7KE 0.8985
238 OJD 0.8984
239 PPN 0.8984
240 TIA 0.8983
241 LI7 0.8983
242 KWB 0.8982
243 TYE 0.8981
244 9YT 0.8979
245 Q06 0.8979
246 SX2 0.8979
247 EQW 0.8978
248 HX4 0.8977
249 LR8 0.8975
250 25F 0.8975
251 7MW 0.8975
252 ING 0.8974
253 KDG 0.8973
254 S0D 0.8972
255 BQ2 0.8972
256 GNW 0.8971
257 2J1 0.8970
258 C53 0.8968
259 D25 0.8968
260 2J3 0.8965
261 4XF 0.8965
262 1ER 0.8964
263 3VS 0.8963
264 JGY 0.8962
265 D26 0.8961
266 PPY 0.8961
267 22F 0.8958
268 272 0.8956
269 OA1 0.8954
270 QME 0.8954
271 JWS 0.8952
272 SWX 0.8951
273 E9S 0.8951
274 YOF 0.8950
275 D8Q 0.8950
276 3F4 0.8950
277 SZ5 0.8949
278 GB5 0.8948
279 ILO 0.8947
280 N91 0.8947
281 3R4 0.8946
282 IQZ 0.8946
283 FQX 0.8945
284 YE7 0.8942
285 GGB 0.8942
286 3D3 0.8942
287 4TB 0.8938
288 M78 0.8937
289 9FH 0.8937
290 0OL 0.8934
291 DHC 0.8934
292 1V3 0.8933
293 EGV 0.8932
294 IC9 0.8930
295 52F 0.8928
296 S7D 0.8928
297 5LD 0.8926
298 RGK 0.8925
299 YZM 0.8924
300 HNT 0.8924
301 CBE 0.8923
302 9UL 0.8923
303 4GU 0.8922
304 AVO 0.8922
305 5GV 0.8921
306 DAR 0.8919
307 2LW 0.8917
308 3IL 0.8917
309 CIR 0.8917
310 N1E 0.8916
311 0FR 0.8916
312 1A7 0.8915
313 WLH 0.8912
314 6P3 0.8910
315 6L6 0.8910
316 HQJ 0.8909
317 HXY 0.8909
318 MW5 0.8906
319 S8G 0.8906
320 IDZ 0.8905
321 9NB 0.8904
322 5NN 0.8903
323 HNM 0.8901
324 XRX 0.8901
325 N4E 0.8900
326 3TC 0.8900
327 7FU 0.8899
328 D1Y 0.8899
329 API 0.8898
330 DTR 0.8898
331 YZ9 0.8896
332 1YO 0.8894
333 3SU 0.8893
334 YIP 0.8893
335 FMQ 0.8891
336 2QC 0.8890
337 B5A 0.8890
338 7VP 0.8890
339 1ZC 0.8890
340 4BX 0.8888
341 J38 0.8887
342 QR2 0.8886
343 M74 0.8885
344 3CX 0.8885
345 AVX 0.8885
346 BL0 0.8883
347 WV7 0.8882
348 IQ5 0.8882
349 X0U 0.8880
350 7ZL 0.8879
351 BZM 0.8879
352 NIY 0.8879
353 SYE 0.8878
354 OQC 0.8878
355 PBN 0.8878
356 P80 0.8875
357 3GX 0.8874
358 0DF 0.8873
359 TIZ 0.8873
360 3H2 0.8870
361 RCV 0.8870
362 XEV 0.8869
363 2UD 0.8868
364 L5V 0.8867
365 4Z9 0.8867
366 F4K 0.8867
367 JF8 0.8867
368 6CL 0.8866
369 M5H 0.8864
370 UN3 0.8862
371 THM 0.8861
372 92G 0.8860
373 AJG 0.8856
374 DRG 0.8855
375 1SF 0.8854
376 H4E 0.8853
377 A7H 0.8852
378 3XH 0.8852
379 TT4 0.8851
380 4YZ 0.8850
381 FER 0.8850
382 1HR 0.8849
383 OOG 0.8849
384 LIG 0.8846
385 0A1 0.8843
386 GXD 0.8843
387 4BL 0.8843
388 4NP 0.8843
389 OLU 0.8840
390 AHC 0.8839
391 KPV 0.8839
392 5S9 0.8839
393 KF5 0.8837
394 EV2 0.8837
395 HPP 0.8835
396 S62 0.8835
397 RVE 0.8834
398 CK2 0.8832
399 5V7 0.8831
400 AOT 0.8830
401 5TT 0.8829
402 FCW 0.8828
403 V2Z 0.8824
404 J4K 0.8822
405 GB4 0.8818
406 U4J 0.8816
407 HC4 0.8816
408 CSN 0.8815
409 MGB 0.8815
410 GAE 0.8814
411 6H2 0.8814
412 DUR 0.8814
413 AHN 0.8811
414 J1K 0.8810
415 ALE 0.8809
416 0F9 0.8809
417 4BY 0.8808
418 T03 0.8807
419 VC3 0.8805
420 BPY 0.8804
421 EAJ 0.8804
422 HIC 0.8804
423 F4E 0.8803
424 P81 0.8802
425 A7Q 0.8801
426 BGU 0.8801
427 TB8 0.8801
428 PA5 0.8800
429 5WN 0.8800
430 3QV 0.8800
431 PPT 0.8799
432 LVD 0.8795
433 CH9 0.8793
434 HSA 0.8792
435 TCA 0.8792
436 PQM 0.8792
437 4ZF 0.8790
438 ZRL 0.8790
439 DBE 0.8790
440 1EB 0.8788
441 DY8 0.8788
442 KWV 0.8787
443 SSC 0.8787
444 6ZX 0.8787
445 0JD 0.8786
446 5ER 0.8784
447 J9N 0.8783
448 4JK 0.8782
449 WT2 0.8782
450 TID 0.8782
451 657 0.8782
452 QKU 0.8782
453 5OO 0.8780
454 CK1 0.8780
455 GO8 0.8780
456 A5E 0.8779
457 3ZB 0.8779
458 4CN 0.8778
459 G30 0.8775
460 XIZ 0.8775
461 0A9 0.8774
462 NDD 0.8773
463 MPV 0.8773
464 344 0.8772
465 WDW 0.8772
466 HCI 0.8772
467 T2D 0.8770
468 V1T 0.8768
469 1HP 0.8767
470 A98 0.8767
471 VFJ 0.8767
472 1L5 0.8766
473 NMM 0.8764
474 ZIQ 0.8763
475 JX7 0.8763
476 WA1 0.8763
477 8NB 0.8763
478 G6Q 0.8763
479 MZM 0.8761
480 1OS 0.8760
481 HAR 0.8760
482 GNR 0.8760
483 GCO 0.8757
484 0OK 0.8757
485 B3U 0.8755
486 THA 0.8755
487 XIF XYP 0.8755
488 1SV 0.8754
489 GRQ 0.8754
490 5TY 0.8754
491 TPM 0.8754
492 EUE 0.8753
493 K7H 0.8753
494 4NS 0.8753
495 RD4 0.8752
496 PZX 0.8751
497 4MB 0.8750
498 3KJ 0.8745
499 S0E 0.8744
500 S60 0.8743
501 SLS 0.8743
502 9PL 0.8742
503 NFA 0.8742
504 5O5 0.8741
505 YIH 0.8741
506 BSU 0.8740
507 PRO GLY 0.8740
508 CKA 0.8740
509 36Y 0.8739
510 80G 0.8739
511 4Z3 0.8738
512 DEW 0.8737
513 EUH 0.8736
514 BVA 0.8736
515 RLG 0.8736
516 6TZ 0.8735
517 TYC 0.8734
518 AN3 0.8733
519 PNP 0.8732
520 BBY 0.8732
521 CNI 0.8732
522 94W 0.8731
523 5O6 0.8731
524 245 0.8731
525 GVA 0.8730
526 XYP XIF 0.8730
527 VUP 0.8730
528 ANC 0.8728
529 E1T 0.8727
530 MR6 0.8726
531 92O 0.8726
532 DIR 0.8725
533 DLT 0.8725
534 SKF 0.8723
535 39Z 0.8723
536 15N 0.8723
537 TZP 0.8723
538 Q9T 0.8719
539 ITE 0.8718
540 5P3 0.8718
541 GF4 0.8718
542 549 0.8716
543 DX2 0.8713
544 M3L 0.8711
545 JVD 0.8711
546 XRS 0.8710
547 THU 0.8709
548 E8U 0.8709
549 DTE 0.8708
550 7OD 0.8706
551 56D 0.8706
552 4LW 0.8705
553 1OT 0.8703
554 PMV 0.8702
555 5GT 0.8702
556 61M 0.8702
557 K4V 0.8702
558 6J5 0.8702
559 ANF 0.8700
560 H35 0.8697
561 428 0.8696
562 4AF 0.8695
563 ZYQ 0.8694
564 5AD 0.8693
565 5SJ 0.8692
566 FYR 0.8691
567 EAE 0.8690
568 GNV 0.8689
569 90G 0.8689
570 Q9Z 0.8688
571 GHQ 0.8688
572 MXD 0.8686
573 38E 0.8685
574 397 0.8684
575 PJW 0.8683
576 5DL 0.8682
577 9F8 0.8682
578 U14 0.8681
579 A29 0.8681
580 9VQ 0.8681
581 MR5 0.8680
582 ESX 0.8676
583 2QV 0.8673
584 MUK 0.8673
585 Q0K 0.8672
586 P4T 0.8671
587 4FE 0.8670
588 AP6 0.8669
589 EF9 0.8669
590 1FL 0.8669
591 Z21 0.8667
592 ONR 0.8666
593 BNL 0.8666
594 CDJ 0.8666
595 CPZ 0.8663
596 MR4 0.8662
597 6QF 0.8662
598 XEN 0.8662
599 JP2 0.8661
600 7R4 0.8660
601 S6P 0.8658
602 D4G 0.8655
603 64Z 0.8652
604 H4B 0.8650
605 1Z6 0.8649
606 LJ3 0.8649
607 3YP 0.8648
608 GXG 0.8648
609 GGG 0.8647
610 HL6 0.8647
611 0MB 0.8646
612 BZE 0.8646
613 A5Q 0.8645
614 EES 0.8644
615 YF3 0.8643
616 7G2 0.8643
617 XDN XYP 0.8638
618 RF2 0.8635
619 NNH 0.8632
620 2JK 0.8631
621 MSR 0.8631
622 2HC 0.8630
623 AGP 0.8626
624 9ZE 0.8625
625 SNU 0.8625
626 ITW 0.8624
627 GZV 0.8624
628 CC5 0.8624
629 7PJ 0.8623
630 9R5 0.8623
631 IS2 0.8620
632 HJ7 0.8620
633 RDM 0.8618
634 27M 0.8617
635 VT3 0.8617
636 5RP 0.8615
637 E9L 0.8614
638 AES 0.8613
639 N2I 0.8612
640 M3W 0.8612
641 AHL 0.8612
642 DZA 0.8610
643 7MX 0.8610
644 ZEA 0.8610
645 QBP 0.8609
646 W8L 0.8608
647 TH4 0.8608
648 HA5 0.8608
649 A63 0.8607
650 TEG 0.8607
651 P1J 0.8606
652 58X 0.8605
653 DA2 0.8604
654 PO6 0.8603
655 1F1 0.8603
656 CFA 0.8602
657 HLP 0.8602
658 H2W 0.8601
659 EZL 0.8598
660 NY4 0.8598
661 IOS 0.8596
662 CX4 0.8594
663 M6Z 0.8591
664 PQV 0.8591
665 FDR 0.8586
666 XDL XYP 0.8586
667 XIL 0.8586
668 PML 0.8581
669 HBI 0.8580
670 2NP 0.8577
671 CUE 0.8576
672 FZ0 0.8574
673 CHQ 0.8573
674 2K8 0.8572
675 30G 0.8572
676 08C 0.8569
677 UN1 0.8565
678 4KJ 0.8562
679 1QP 0.8559
680 6PG 0.8558
681 ALA PHE 0.8555
682 ENV 0.8555
683 CX6 0.8554
684 TCC 0.8546
685 BIO 0.8542
686 ZSP 0.8541
687 N7I 0.8523
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6C6O; Ligand: ENG; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 6c6o.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 4L9Z OXL 5.01475
2 4L9Z OXL 5.01475
3 4L9Z OXL 5.01475
4 4L9Z OXL 5.01475
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