-->
Receptor
PDB id Resolution Class Description Source Keywords
5C2N 1.65 Å NON-ENZYME: OTHER THE DE NOVO EVOLUTIONARY EMERGENCE OF A SYMMETRICAL PROTEIN BY FOLDING CONSTRAINTS ENTEROBACTERIA PHAGE L1 BLADED BETA PROPELLER UNKNOWN FUNCTION
Ref.: DE NOVO EVOLUTIONARY EMERGENCE OF A SYMMETRICAL PRO SHAPED BY FOLDING CONSTRAINTS. CELL V. 164 476 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG L:102;
C:101;
O:101;
B:101;
D:101;
E:102;
M:101;
L:101;
E:101;
J:101;
M:102;
F:101;
A:101;
I:101;
F:102;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5C2N 1.65 Å NON-ENZYME: OTHER THE DE NOVO EVOLUTIONARY EMERGENCE OF A SYMMETRICAL PROTEIN BY FOLDING CONSTRAINTS ENTEROBACTERIA PHAGE L1 BLADED BETA PROPELLER UNKNOWN FUNCTION
Ref.: DE NOVO EVOLUTIONARY EMERGENCE OF A SYMMETRICAL PRO SHAPED BY FOLDING CONSTRAINTS. CELL V. 164 476 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5C2N - NAG C8 H15 N O6 CC(=O)N[C@....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5C2N - NAG C8 H15 N O6 CC(=O)N[C@....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5C2N - NAG C8 H15 N O6 CC(=O)N[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAG; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 NGA 1 1
2 NAG 1 1
3 A2G 1 1
4 BM3 1 1
5 HSQ 1 1
6 NDG 1 1
7 BGN 0.638298 0.888889
8 SIZ 0.630435 0.906977
9 YX1 0.625 0.65
10 STZ 0.612245 0.65
11 4QY 0.591837 0.735849
12 BMX 0.591837 0.735849
13 16G 0.591837 0.735849
14 9C1 0.58 0.886364
15 SNG 0.5625 0.866667
16 NGS 0.54902 0.661017
17 NDG NAG 0.54386 0.833333
18 CBS 0.54386 0.833333
19 NAG GDL 0.54386 0.833333
20 CBS CBS 0.54386 0.833333
21 ASG 0.538462 0.661017
22 BG8 0.537037 0.906977
23 MAG 0.530612 0.909091
24 2F8 0.530612 0.909091
25 NDG GAL 0.517857 0.888889
26 NLC 0.517857 0.888889
27 GAL NDG 0.517857 0.888889
28 NAG A2G 0.517241 0.833333
29 4V5 0.517241 0.829787
30 NAG NGA 0.517241 0.833333
31 4UZ 0.508475 0.808511
32 NAG NAG NAG NAG NDG 0.508197 0.816327
33 NDG NAG NAG NAG 0.508197 0.816327
34 NAG NAG NDG 0.508197 0.816327
35 NAG NAG NDG NAG 0.508197 0.816327
36 CTO 0.508197 0.816327
37 NDG NAG NAG NDG 0.508197 0.816327
38 NAG NAG NAG NDG 0.508197 0.816327
39 NDG NAG NAG 0.508197 0.816327
40 NAG NAG NAG NAG NAG 0.508197 0.816327
41 NAG NAG NAG NAG NAG NAG 0.508197 0.816327
42 NAG NAG NAG NAG NAG NAG NAG NAG 0.508197 0.816327
43 MQG 0.5 0.698113
44 NBG 0.5 0.951219
45 GAL NGA 0.491228 0.888889
46 A2G GAL 0.491228 0.888889
47 GAL A2G 0.491228 0.888889
48 AMU 0.490909 0.930233
49 NG1 0.490566 0.754717
50 GN1 0.490566 0.754717
51 NAG GAL 0.474576 0.888889
52 GAL NAG 0.474576 0.888889
53 NAG FUC 0.474576 0.866667
54 NAG GAL NAG 0.455882 0.833333
55 3YW 0.448276 0.930233
56 GLA GAL NAG 0.446154 0.888889
57 MAN BMA NAG 0.446154 0.888889
58 NGA GAL 0.428571 0.869565
59 FUC GAL NAG 0.426471 0.869565
60 GAL NAG FUC 0.426471 0.869565
61 DR2 0.426471 0.869565
62 NAG GAL FUC 0.426471 0.869565
63 NDG GAL FUC 0.426471 0.869565
64 FUC GAL NDG 0.426471 0.869565
65 FUL GAL NAG 0.426471 0.869565
66 G6S NAG 0.426471 0.645161
67 TNR 0.42623 0.833333
68 GYU 0.42623 0.740741
69 GAL NGA A2G 0.424242 0.833333
70 NAG BDP 0.421875 0.851064
71 NAG MBG 0.419355 0.851064
72 NGA GAL BGC 0.41791 0.888889
73 NAG NDG 0.415385 0.784314
74 NAG NAG 0.415385 0.784314
75 AZC 0.415094 0.795918
76 SN5 SN5 0.412698 0.705882
77 A2G MBG 0.412698 0.851064
78 MBG A2G 0.412698 0.851064
79 HS2 0.411765 0.8125
80 5AX 0.411765 0.866667
81 NAG MAN BMA 0.411765 0.888889
82 6ZC 0.409091 0.655738
83 LEC 0.409091 0.655738
84 TCG 0.408451 0.689655
85 GAL BGC NAG GAL 0.408451 0.888889
86 NAG MAN 0.40625 0.851064
87 WOO 0.404762 0.7
88 MAN 0.404762 0.7
89 GAL 0.404762 0.7
90 BGC 0.404762 0.7
91 BMA 0.404762 0.7
92 GLA 0.404762 0.7
93 ALL 0.404762 0.7
94 GLC 0.404762 0.7
95 GXL 0.404762 0.7
96 GIV 0.404762 0.7
97 NAG AMU 0.402778 0.8
98 NAG MUB 0.402778 0.8
99 NAG A2G GAL 0.402778 0.833333
100 A2G GAL FUC 0.4 0.869565
101 FUC GLA A2G 0.4 0.869565
102 DR3 0.4 0.869565
103 A2G GLA FUC 0.4 0.869565
104 NGA GAL FUC 0.4 0.869565
105 FUC GAL A2G 0.4 0.869565
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 276
This union binding pocket(no: 1) in the query (biounit: 5c2n.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5GG9 8GM None
2 3WGT FAD None
3 3G5S FAD None
4 2H21 SAM None
5 1TLG GAL None
6 1C0I BE2 None
7 1C0I FAD None
8 3C3N FMN None
9 5YSS NAD None
10 1U7Z PMT None
11 1W4R TTP None
12 5AHM IMP None
13 4RVU NDP None
14 6B5G NAD None
15 1T9D P22 None
16 4P6G 2FZ None
17 6B5G CQY None
18 5GZ9 MAN None
19 5J60 FAD None
20 3EWP APR None
21 3TG5 SAH None
22 2XTZ GSP None
23 4RQU NAD None
24 1P1C SAH None
25 3RNM FAD None
26 1P9B GDP None
27 1GZ4 ATP None
28 4L3L 5FI None
29 3IWD M2T None
30 5KJK 6T1 None
31 5KJK SAM None
32 4EOX 0S5 None
33 4BNU 9KQ None
34 5O96 SAM None
35 3QJ4 FAD None
36 4C2X NHW None
37 3VPH OXM None
38 6F7L FAD None
39 3M6P BB2 None
40 6AU6 GDP None
41 2VBU CDP None
42 3SJ7 NDP None
43 1TUF AZ1 None
44 3G5K BB2 None
45 5JF2 SF7 None
46 2FK8 SAM None
47 1IG3 VIB None
48 1IZE IVA VAL VAL STA ALA STA None
49 4IXH IMP None
50 1BH2 GSP None
51 5JGL SAM None
52 3OVR 5SP None
53 5O98 NAP None
54 1WG8 SAM None
55 2A92 NAI None
56 5LJW ANP None
57 4M37 SAH None
58 3QF7 ANP None
59 2QXL ATP None
60 3VC3 C6P None
61 2GJN NIS None
62 5WKC TP9 None
63 2A2C NG1 4.16667
64 2A2C ADP 4.16667
65 5OBU ANP 4.16667
66 5OBY ANP 4.16667
67 3HQ9 OXL 4.16667
68 6GBC AMP 4.16667
69 1EZ0 NAP 4.16667
70 5WA0 MSS 4.16667
71 1ZX5 LFR 4.16667
72 1E6E FAD 4.16667
73 5I60 67W 4.16667
74 4MP8 NAD 4.16667
75 4MP8 MLI 4.16667
76 4PW9 MSS 4.16667
77 5Y77 FAD 4.16667
78 3LCV SAM 4.16667
79 4FN4 NAD 4.16667
80 4UXH T5A 4.16667
81 2BNF UTP 4.16667
82 6DNT NAD 6.25
83 5JCA NDP 6.25
84 4UP4 GAL NAG 6.25
85 1LLU NAD 6.25
86 2AJ4 ANP 6.25
87 1KNM LAT 6.25
88 4OM8 NAD 6.25
89 5HQ8 SAH 6.25
90 3KEE 30B 6.25
91 1XG5 NAP 8.33333
92 1V59 FAD 8.33333
93 1X87 NAD 8.33333
94 4MO2 FAD 8.33333
95 6FTB M0E 8.33333
96 3JVH HHV 8.33333
97 4YRY FAD 8.33333
98 4MO2 FDA 8.33333
99 4O0L NDP 8.33333
100 4MIG G3F 8.33333
101 4NST ADP 8.33333
102 4QGE 35O 8.33333
103 5EFQ ADP 8.33333
104 4GKV NAD 8.33333
105 4D9M 0JO 8.33333
106 5H4S RAM 8.33333
107 5YJF 8WO 8.33333
108 2AMT 1AA 10.4167
109 1D7O NAD 10.4167
110 1D7O TCL 10.4167
111 6GAS FAD 10.4167
112 5HTX ADP 10.4167
113 4AT0 FAD 10.4167
114 5U97 PIT 10.4167
115 2CUL FAD 10.4167
116 5TWB FAD 10.4167
117 6FP4 FAD 10.4167
118 1C1X HFA 10.4167
119 4E5N NAD 10.4167
120 2YY7 NAD 10.4167
121 1VL0 NAI 10.4167
122 5ZBL AMP 10.4167
123 4CQM NAP 10.4167
124 1BW9 PPY 10.4167
125 1SVM ATP 12.5
126 4IV9 FAD 12.5
127 4B9Q ATP 12.5
128 1YQS BSA 12.5
129 2VVL FAD 12.5
130 4N49 SAM 12.5
131 1XHC FAD 12.5
132 4JNE ATP 12.5
133 1XA4 COA 12.5
134 5JIC ADP 12.5
135 2RGH FAD 12.5
136 2VVM FAD 12.5
137 5ZYN FAD 12.5
138 4CBU ATP 12.5
139 2RGO FAD 12.5
140 5GSN FAD 12.5
141 1XVV CCQ 12.5
142 4CBX ATP 12.5
143 6F3M NAD 12.5
144 2CDU ADP 12.5
145 5BRT FAD 12.5
146 1KGZ PRP 12.5
147 1SOX MTE 12.5
148 5Z2L NDP 12.5
149 3MN9 ATP 12.5
150 1APZ ASP 12.5
151 3QWI NAP 12.5
152 1M2O GNP 12.5
153 3MN6 ATP 12.5
154 4II2 ATP 12.5
155 2GQS C2R 12.5
156 2QTV GNP 12.5
157 1COY FAD 14.5833
158 4GUT FAD 14.5833
159 4HSU FAD 14.5833
160 4GUS FAD 14.5833
161 4FWE FAD 14.5833
162 1KNR FAD 14.5833
163 3K7M FAD 14.5833
164 3ZNN 4WL 14.5833
165 3ZNN FAD 14.5833
166 5TUK FAD 14.5833
167 4M52 M52 14.5833
168 2BUP ATP 14.5833
169 2BUP ADP 14.5833
170 1IYK MYA 14.5833
171 3ITJ FAD 14.5833
172 2A9D MTE 14.5833
173 1UKG MMA 14.5833
174 1NVV GNP 14.5833
175 4N02 FNR 14.5833
176 6D55 GNP 14.5833
177 1H5S TMP 14.5833
178 3LDQ 3P1 14.5833
179 6D5E GNP 14.5833
180 5ZBC FAD 14.5833
181 6D56 GNP 14.5833
182 6D59 GNP 14.5833
183 6D5J GNP 14.5833
184 6BVM GNP 14.5833
185 6D5L GNP 14.5833
186 1Q8S MAN MMA 14.5833
187 1Q8Q MAN MMA 14.5833
188 6D5M GNP 14.5833
189 2R4J 13P 16.6667
190 2R4J FAD 16.6667
191 2VTD LKM 16.6667
192 4MOP 2H5 16.6667
193 5ODQ FAD 16.6667
194 5TS5 FAD 16.6667
195 3Q9T FAY 16.6667
196 4NVQ SAH 16.6667
197 1DJN ADP 16.6667
198 1IV2 CDP 16.6667
199 3U4L ATP 16.6667
200 4NVQ 2OD 16.6667
201 1ZC3 GNP 16.6667
202 4IP7 FBP 16.6667
203 3QXY SAM 18.75
204 3CTY FAD 18.75
205 2V51 ATP 18.75
206 4USR FAD 18.75
207 2PBD ATP 18.75
208 2A42 ATP 18.75
209 2Q97 ATP 18.75
210 4PKG ATP 18.75
211 4J56 FAD 18.75
212 5ZZB ATP 18.75
213 4PKI ATP 18.75
214 2A40 ATP 18.75
215 4B1V LAB 18.75
216 4B1X ATP 18.75
217 1KXP ATP 18.75
218 5YPU ATP 18.75
219 4B1V ATP 18.75
220 4PL8 ATP 18.75
221 5JBE GLC GLC GLC GLC GLC 18.75
222 3U9Z ADP 18.75
223 2D1K ATP 18.75
224 4H03 ATP 18.75
225 4H03 LAR 18.75
226 2PAV ATP 18.75
227 5YEE ATP 18.75
228 3MN5 ATP 18.75
229 2QZX IVA VAL VAL STA ALA STA 18.75
230 4D9C PMP 18.75
231 2A3Z ATP 18.75
232 4Z94 ATP 18.75
233 4B1W ATP 18.75
234 3ICT COA 18.75
235 3ICS COA 18.75
236 5YLT C7N 20.8333
237 5YLT SFG 20.8333
238 3F8D FAD 20.8333
239 1I8T FAD 20.8333
240 1JG9 GLC 20.8333
241 4NAE 1GP 20.8333
242 5EXW 7DT 20.8333
243 5THQ NDP 20.8333
244 5OVL NAP 20.8333
245 3CX8 GSP 20.8333
246 2A14 SAH 20.8333
247 1W6U NAP 20.8333
248 4J8O SAH 20.8333
249 2E5V FAD 22.9167
250 6F97 FAD 22.9167
251 5ERG SAM 22.9167
252 6GAR FAD 22.9167
253 4URF NAD 22.9167
254 5JJR 68E 22.9167
255 4NBT NAD 22.9167
256 1O94 ADP 25
257 3MAG SAH 25
258 3X0V FAD 27.0833
259 5GLN XYS 27.0833
260 5GLN XYP XYP XYP 27.0833
261 4C8E C5P 27.0833
262 3RO7 TDR 27.0833
263 1GPE FAD 29.1667
264 4XQC NAD 29.1667
265 4XQC 13D 29.1667
266 3SSO SAH 29.1667
267 4U8P FDA 31.25
268 4U8P UDP 31.25
269 1AE1 NAP 31.25
270 4ZRN NAD 33.3333
271 4ZRN UPG 33.3333
272 6CI9 NAP 35.4167
273 3QFA FAD 37.5
274 1Z45 NAD 37.5
275 1QO8 FAD 39.5833
276 6H3O FAD 41.6667
Pocket No.: 2; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 98
This union binding pocket(no: 2) in the query (biounit: 5c2n.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5HSA FAS None
2 2JL1 NAP None
3 3GDN FAD None
4 2GJ8 ALF GDP None
5 6FA4 GNP None
6 5GT9 NAP None
7 3WQT ANP None
8 5TUZ SAM None
9 5TUZ 7L6 None
10 1GUZ NAD None
11 5OCG GNP None
12 4TXJ THM None
13 1VBJ NAP None
14 1ZUI SKM None
15 4B2D FBP None
16 1V8B NAD None
17 4C1Q SAH None
18 1L7N ALF None
19 4NBU NAI None
20 1L5Y BEF None
21 1LDN NAD None
22 1ZGD NAP None
23 5Z75 NAD None
24 2AG5 NAD None
25 1GV0 NAD None
26 3LU1 NAD 4.16667
27 3JSX FAD 4.16667
28 5JCA FAD 6.25
29 2IHU TP9 6.25
30 1PJS SAH 6.25
31 3P8N L4T 6.25
32 1P9P SAH 6.25
33 2VDV SAM 6.25
34 2C6Q IMP 6.25
35 1GUA GNP 8.33333
36 2IVD FAD 8.33333
37 1EXF GLY 8.33333
38 4HDO GNP 8.33333
39 3WMX NAD 8.33333
40 4O1M NAD 10.4167
41 2YG3 FAD 10.4167
42 3LZW FAD 10.4167
43 4JDR FAD 10.4167
44 3LST SAH 10.4167
45 2D0O ADP 10.4167
46 1U5R ATP 10.4167
47 1H5Q NAP 10.4167
48 4UCI SAM 10.4167
49 1YAG ATP 12.5
50 2CSN CKI 12.5
51 1FK8 NAD 12.5
52 5G3U ITW 14.5833
53 6BVI GNP 14.5833
54 6BVK GNP 14.5833
55 6D5V GNP 14.5833
56 6BVL GNP 14.5833
57 6D5G GNP 14.5833
58 6D5H GNP 14.5833
59 6BVJ GNP 14.5833
60 2Q7V FAD 14.5833
61 5WGR FAD 14.5833
62 5FPE 3TR 14.5833
63 1WD4 AHR 14.5833
64 1HXD BTN 14.5833
65 6G3R ADP 14.5833
66 3DDC GNP 14.5833
67 1GEG NAD 14.5833
68 5EEH SAH 14.5833
69 5K4W NAI 14.5833
70 4K81 GTP 14.5833
71 2OKK ABU 14.5833
72 5AR0 GB8 14.5833
73 2C7G FAD 16.6667
74 3AYI HCI 16.6667
75 3AYI FAD 16.6667
76 1SAY PYR 16.6667
77 3F4F UMP 16.6667
78 5XFV FMN 16.6667
79 1YXM ADE 16.6667
80 1BC5 SAH 16.6667
81 1YBH P22 16.6667
82 1JG3 ADN 16.6667
83 4OH4 ANP 16.6667
84 6D6Y SAH 18.75
85 2FXU ATP 18.75
86 3SJH LAR 18.75
87 5UR1 YY9 18.75
88 3SJH ATP 18.75
89 1YZN GNP 20.8333
90 1MT6 SAH 20.8333
91 1W8D NAP 20.8333
92 3A28 NAD 22.9167
93 1H0H 2MD 25
94 3LXK MI1 25
95 4Y30 49L 29.1667
96 4Y30 SAH 29.1667
97 3QVP FAD 37.5
98 1MI3 NAD 39.5833
Pocket No.: 3; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 103
This union binding pocket(no: 3) in the query (biounit: 5c2n.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 3WGT QSC None
2 4L2H AR6 AR6 None
3 3O26 NDP None
4 4J4H 1J1 None
5 4J4H NAI None
6 5FFF NAP None
7 2GU8 796 None
8 1OAA OAA None
9 4J7U YTZ None
10 4J7U NAP None
11 5XDT MB3 None
12 5FEU NAP None
13 5A89 FMN None
14 5A89 ADP None
15 6GNC FAD None
16 3RUV ANP None
17 2JAH NDP None
18 3WLE NAD None
19 2DT5 NAD None
20 5X9D 80F None
21 2JAP NDP None
22 1G27 BB1 None
23 1BB6 UMG None
24 2HMT NAI None
25 5OVK NDP None
26 2ZIF SAM None
27 4JK3 NAD None
28 1UPT GTP None
29 3TN7 NJP 4.16667
30 5J5R 6G1 4.16667
31 5J5R IMP 4.16667
32 1WMA NDP 4.16667
33 1WMA AB3 4.16667
34 1XS1 DUT 4.16667
35 1W78 ADP 4.16667
36 2C6Q NDP 6.25
37 1HYH NAD 6.25
38 1UPA TPP 6.25
39 3BC1 GNP 6.25
40 1UWK URO 8.33333
41 1UWK NAD 8.33333
42 1PVN MZP 8.33333
43 2V7Y ADP 8.33333
44 5YU3 NAD 8.33333
45 5YU3 PRO 8.33333
46 2XVF FAD 8.33333
47 2WTX VDO 8.33333
48 4DSG FAD 10.4167
49 4DSG UDP 10.4167
50 1RSG FAD 10.4167
51 1C1X NAD 10.4167
52 1BW9 NAD 10.4167
53 4Z0G 5GP 10.4167
54 1YY5 FAD 10.4167
55 5J7X FAD 10.4167
56 1EZ4 NAD 10.4167
57 4US3 TRP 10.4167
58 3GRU AMP 10.4167
59 5GSN NAP 12.5
60 5GSN MMZ 12.5
61 1ME8 RVP 12.5
62 2BHZ MAL 12.5
63 4EFH ADP 12.5
64 4R5M 4NO 12.5
65 4R5M NAP 12.5
66 1ZFJ IMP 12.5
67 1X7D NAD 12.5
68 5C9P FUC 12.5
69 1Q19 APC 12.5
70 2YVJ NAI 12.5
71 1MO9 KPC 14.5833
72 5G3U FDA 14.5833
73 1PS9 FAD 14.5833
74 5WQP NAP 14.5833
75 3AD8 NAD 14.5833
76 5NMX FAD 14.5833
77 2FFQ GSP 14.5833
78 1GQ2 NAP 14.5833
79 5WQP NCA 14.5833
80 1YZQ GNP 14.5833
81 1P4V GLY 14.5833
82 4YSX FAD 16.6667
83 2AE2 PTO 16.6667
84 2AE2 NAP 16.6667
85 4USQ FAD 16.6667
86 2UZ1 TPP 16.6667
87 4IPE ANP 16.6667
88 3AB1 FAD 18.75
89 1REO FAD 18.75
90 3NTD COA 18.75
91 4AML GYU 18.75
92 1H82 GZZ 20.8333
93 1H82 FAD 20.8333
94 5TTJ FAD 20.8333
95 3PC3 P1T 20.8333
96 5OGX FAD 25
97 4Z87 5GP 25
98 2GMV PEP 25
99 5TH5 7C5 27.0833
100 1GK8 CAP 31.25
101 5YB7 ORN 35.4167
102 5YB7 FAD 35.4167
103 4AF0 IMP 35.4167
Pocket No.: 4; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 47
This union binding pocket(no: 4) in the query (biounit: 5c2n.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5AE2 FAD None
2 5AE2 FYC None
3 5B4T 3HR None
4 5B4T NAD None
5 1Z0S ATP None
6 2F5Z FAD None
7 4MO4 ACP None
8 3H4V NAP None
9 1L1E SAH None
10 1S17 GNR None
11 3CIF NAD None
12 1KPG SAH None
13 5UQW GDP None
14 3KO8 NAD None
15 2ODE ALF GDP None
16 3MJY IJZ 4.16667
17 3MJY FMN 4.16667
18 5M58 SAH 4.16667
19 1N5D NDP 4.16667
20 5CCM SAM 6.25
21 3E3U NVC 6.25
22 1D8C SOR 8.33333
23 5OC1 FAD 10.4167
24 5MGZ SAH 10.4167
25 2HQM FAD 12.5
26 3QWI CUE 12.5
27 5UKL SIX 12.5
28 1T3D CYS 12.5
29 3MN7 ATP 12.5
30 3ZOK GLY 14.5833
31 6ARJ SAH 14.5833
32 1U1F 183 14.5833
33 3K56 IS3 14.5833
34 3O3R NAP 14.5833
35 1Q7B NAP 14.5833
36 1PHP ADP 16.6667
37 1GTE FAD 18.75
38 4RSL FAD 18.75
39 3NTA COA 18.75
40 5YJI SAH 18.75
41 5YJI 8WO 18.75
42 1JIF CU BLM 18.75
43 2F69 SAH 20.8333
44 3M54 SAH 20.8333
45 4YBN FAD 25
46 2BFR ADP 29.1667
47 1TDF FAD 33.3333
Pocket No.: 5; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 19
This union binding pocket(no: 5) in the query (biounit: 5c2n.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4WZH FMN None
2 3BXF 13P None
3 5EP2 AZU None
4 1SQL GUN None
5 1LOJ URI None
6 1VG8 GNP None
7 2AQJ FAD 4.16667
8 2AQJ TRP 4.16667
9 2BLE 5GP 6.25
10 5YJF SAH 8.33333
11 4J5R A1R 8.33333
12 1Y8Q ATP 8.33333
13 3DRW AMP 8.33333
14 2PHN GDP 10.4167
15 2FP2 TSA 10.4167
16 1JA9 NDP 12.5
17 2DXU BT5 14.5833
18 1YKI NFZ 22.9167
19 1EM6 NBG 25
Pocket No.: 6; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 19
This union binding pocket(no: 6) in the query (biounit: 5c2n.bio3) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4NTD FAD None
2 3GF4 UPG None
3 3GF4 FAD None
4 1IIM TTP None
5 1N07 ADP None
6 5WKC AUJ None
7 4K26 NDP None
8 1P4A PCP None
9 2WTX UDP 8.33333
10 5EOW FAD 10.4167
11 1YRB GDP 10.4167
12 5JIC N7E 12.5
13 3C6K SPD 12.5
14 3C6K MTA 12.5
15 2Z3Y F2N 12.5
16 3KUD GDP 14.5833
17 1WA5 GTP 14.5833
18 3UA1 08Y 25
19 2H6T IVA VAL VAL STA ALA STA 29.1667
Pocket No.: 7; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 21
This union binding pocket(no: 7) in the query (biounit: 5c2n.bio3) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 2RAB FAD None
2 5L4S NAP None
3 5L4S 6KX None
4 4Y9D NAI None
5 1X1T NAD None
6 3FG2 FAD None
7 4OOP DUP None
8 5T2U NAP None
9 1KPH SAH None
10 4EHU ANP 4.16667
11 6A3J NAI 4.16667
12 4EIL NDP 6.25
13 3LZW NAP 10.4167
14 2B4Q NAP 10.4167
15 1Z6Z NAP 12.5
16 3CIP ATP 12.5
17 1MO9 FAD 14.5833
18 1ON3 MCA 16.6667
19 4REP FAD 18.75
20 1Z3C SA8 18.75
21 1KYQ NAD 20.8333
Pocket No.: 8; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 24
This union binding pocket(no: 8) in the query (biounit: 5c2n.bio3) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5E1M PRO PRO LYS ARG ILE ALA None
2 5E1M SAH None
3 1N07 FMN None
4 3D3W NAP None
5 1VL8 NAP None
6 1PR9 NAP None
7 3S7D SAH None
8 2Q2V NAD None
9 4OXI GAP None
10 2BNE U5P 4.16667
11 3AXB FAD 8.33333
12 6FP4 E1T 10.4167
13 5AZC PGT 10.4167
14 1GZ6 NAI 12.5
15 1UYY BGC BGC 12.5
16 3EYA TDP 12.5
17 4KWI NAP 14.5833
18 4ZLU 4PW 16.6667
19 4ZLU ADP 16.6667
20 3BIB PSF 16.6667
21 4HA6 FAD 22.9167
22 1NAA 6FA 22.9167
23 2NVA PL2 22.9167
24 5EYK 5U5 25
Pocket No.: 9; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 23
This union binding pocket(no: 9) in the query (biounit: 5c2n.bio3) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 2O07 SPD None
2 2O07 MTA None
3 1XDY MTE None
4 1UZN NAP None
5 2O4C NAD None
6 3H8V ATP 4.16667
7 2NVK FAD 6.25
8 4ZCC FAD 6.25
9 3AB4 THR 6.25
10 4YRY NAD 8.33333
11 2VJ8 HA2 10.4167
12 3EKK GS2 10.4167
13 1WY7 SAH 10.4167
14 1PTR PRB 12.5
15 1LDM NAD 12.5
16 4N8I COA 12.5
17 2BEK ATP 14.5833
18 3GD4 NAD 14.5833
19 3H7U NAP 16.6667
20 5UY8 8UM 18.75
21 5UY8 AMZ 18.75
22 1W73 NAP 20.8333
23 4N9I PCG 22.9167
Pocket No.: 10; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 11
This union binding pocket(no: 10) in the query (biounit: 5c2n.bio3) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5FFF 5XC None
2 5EVY FAD None
3 1CZR FMN None
4 2TPI ILE VAL 8.33333
5 5ZBK AMP 10.4167
6 4C3Y FAD 10.4167
7 3GYQ SAM 10.4167
8 2GQT FAD 14.5833
9 5U8U FAD 14.5833
10 4M52 FAD 14.5833
11 1TLL FMN 16.6667
Pocket No.: 11; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 10
This union binding pocket(no: 11) in the query (biounit: 5c2n.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 1KOL NAD None
2 3JYN NDP None
3 1I52 CTP None
4 4DV8 0LX 6.25
5 5XWV NDP 6.25
6 5XWV 8H6 6.25
7 6ARJ BW4 14.5833
8 2QWO ADP 14.5833
9 3FV3 IVA VAL VAL STA ALA STA 14.5833
10 1NAA ABL 22.9167
Pocket No.: 12; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 22
This union binding pocket(no: 12) in the query (biounit: 5c2n.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 2BD0 NAP None
2 2B4R AES None
3 3CIF G3H None
4 4CNG SAH None
5 3SIG AR6 6.25
6 4X9M FAD 6.25
7 4RDI ATP 6.25
8 3JQ7 NAP 12.5
9 2IID PHE 14.5833
10 2IID FAD 14.5833
11 1BZL FAD 14.5833
12 4KWI 1TJ 14.5833
13 4W6Z 8ID 14.5833
14 3W8X FTK 16.6667
15 3W8X FAD 16.6667
16 1LVK MNT BEF 18.75
17 1SQK ADP 18.75
18 2PZM UDP 20.8333
19 2PZM NAD 20.8333
20 2V63 CAP 31.25
21 2VDH CAP 31.25
22 3CQD ATP 31.25
Pocket No.: 13; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 15
This union binding pocket(no: 13) in the query (biounit: 5c2n.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 3EWR APR None
2 5O2T GSP None
3 2CFC NAD None
4 3T1O GDP None
5 3FRH SAH 4.16667
6 1S4M LUM 6.25
7 3VX3 ADP 6.25
8 1VPE ANP 8.33333
9 5W7M SAH 10.4167
10 3CGD COA 14.5833
11 3CGD FAD 14.5833
12 5K4W THR 14.5833
13 3QOX SAH 14.5833
14 4NEC SAH 14.5833
15 1T5B FMN 16.6667
Pocket No.: 14; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 10
This union binding pocket(no: 14) in the query (biounit: 5c2n.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4P7U 1PS None
2 1SVK ALF GDP None
3 1R4A GNP None
4 3QDL FMN None
5 5TWJ SAM None
6 4D79 ATP 6.25
7 1T3Q FAD 12.5
8 2C5L GTP 14.5833
9 1LFD GNP 14.5833
10 5ODQ 9SB 16.6667
Pocket No.: 15; Query (leader) PDB : 5C2N; Ligand: NAG; Similar sites found with APoc: 10
This union binding pocket(no: 15) in the query (biounit: 5c2n.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 1H74 ADP 1.01351
2 1LVL FAD 4.16667
3 1RM0 NAI 8.33333
4 4GLL NAD 8.33333
5 6ER9 FAD 12.5
6 1N62 FAD 12.5
7 1EDO NAP 12.5
8 5UWS GNP 14.5833
9 2C29 DQH 25
10 2OO0 XAP 25
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