Receptor
PDB id Resolution Class Description Source Keywords
5C0M 1.6 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF SGF29 TANDEM TUDOR DOMAIN IN COMPLEX WI CONTAINING PEPTIDE HOMO SAPIENS SGF29 TANDEM TUDOR DOMAIN CARBA CONTAINING PEPTIDE STRUCTGENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TRANSCRIPTIO
Ref.: CHEMICAL BASIS FOR THE RECOGNITION OF TRIMETHYLLYSI EPIGENETIC READER PROTEINS. NAT COMMUN V. 6 8911 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 B:301;
A:301;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
UNX A:303;
B:304;
B:303;
A:305;
A:302;
B:305;
A:304;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
n/a X *
ALA ARG THR 4WQ GLN THR ALA ARG LYS SER C:1;
D:1;
Valid;
Valid;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
Kd = 1.4 uM
572.752 n/a O=C(N...
GOL B:302;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5C0M 1.6 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF SGF29 TANDEM TUDOR DOMAIN IN COMPLEX WI CONTAINING PEPTIDE HOMO SAPIENS SGF29 TANDEM TUDOR DOMAIN CARBA CONTAINING PEPTIDE STRUCTGENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TRANSCRIPTIO
Ref.: CHEMICAL BASIS FOR THE RECOGNITION OF TRIMETHYLLYSI EPIGENETIC READER PROTEINS. NAT COMMUN V. 6 8911 2015
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3MEV - ALA ALA THR M3L GLN THR ALA ARG n/a n/a
2 5C0M Kd = 1.4 uM ALA ARG THR 4WQ GLN THR ALA ARG LYS SER n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3MEV - ALA ALA THR M3L GLN THR ALA ARG n/a n/a
2 5C0M Kd = 1.4 uM ALA ARG THR 4WQ GLN THR ALA ARG LYS SER n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3MEV - ALA ALA THR M3L GLN THR ALA ARG n/a n/a
2 5C0M Kd = 1.4 uM ALA ARG THR 4WQ GLN THR ALA ARG LYS SER n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ALA ARG THR 4WQ GLN THR ALA ARG LYS SER; Similar ligands found: 75
No: Ligand ECFP6 Tc MDL keys Tc
1 ALA ARG THR 4WQ GLN THR ALA ARG LYS SER 1 1
2 ALA ARG THR M3L GLN THR ALA 2MR LYS 0.673913 0.854839
3 ALA ARG THR ALY GLN THR ALA 0.673913 0.892857
4 ALA ARG THR M3L GLN THR ALA 0.673913 0.854839
5 ALA ALA LEU THR ARG ALA 0.662921 0.888889
6 ALA ARG THR ALA ALA THR ALA ARG LYS SER 0.662791 0.836364
7 ALA ARG THR MLY GLN THR ALA 0.659574 0.852459
8 ALA ARG THR MLY GLN THR ALA ARG LYS TYR 0.659574 0.852459
9 ALA ARG 9AT 0.64 0.851852
10 ALA ARG THR LYS GLN THR ALA ARG 0.602151 0.872727
11 ALA ARG THR M3L GLN THR ALA ARG LYS 0.597938 0.854839
12 ALA ARG THR M3L GLN THR ALA ARG LYS SER 0.597938 0.854839
13 ALA ARG THR MLY GLN THR ALA ARG LYS 0.585859 0.866667
14 ALA ARG THR MLZ GLN THR ALA ARG LYS TYR 0.585859 0.894737
15 ALA ARG THR MLY GLN THR ALA ARG MLY SER 0.583333 0.866667
16 ALA ARG THR MLY GLN THR ALA ARG LYS SER 0.576087 0.821429
17 ILE LYS ARG SER MLZ LYS ASN SER LEU ALA 0.565217 0.877193
18 ALA ARG THR LYS GLN THR ALA ARG LYS 0.548077 0.857143
19 ARG ARG ARG GLU THR GLN VAL 0.541667 0.842105
20 ALA ARG THR MLY GLN 0.540816 0.852459
21 ALA ARG THR MLZ GLN THR ALA ARG LYS 0.527778 0.87931
22 PRO ALA ALA LYS ARG VAL LYS LEU ASP 0.521739 0.796296
23 ALA ARG THR M3L GLN THR ALA ARG 0.509434 0.84127
24 ACE ALA ARG THR LYS GLN 0.484848 0.888889
25 ALA ILE ARG SER 0.483871 0.785714
26 ALA ARG THR M3L GLN THR ALA ALA LYS ALA 0.482456 0.84127
27 ALA ARG M3L SER 0.478723 0.806452
28 ACE ARG LYS VAL ARG MET 5XU 0.478261 0.754386
29 ARG LEU GLN ARG ARG ARG GLU THR GLN VAL 0.46789 0.859649
30 ALA ARG THR LYS GLN THR ALA ARG LYS SER 0.467391 0.745455
31 ILE LYS ARG SER LYS LYS ASN SER LEU ALA 0.463158 0.836364
32 THR ARG ARG GLU THR GLN LEU 0.457143 0.859649
33 ALA ARG ALA ALA ALA ALA ALA ALA ALA 0.454545 0.745455
34 ALA THR ARG ASN PHE SER GLY 0.452174 0.741935
35 GLU ARG THR ILE PRO ILE THR ARG GLU 0.449153 0.720588
36 ARG ILE ALA ALA ALA 0.448276 0.727273
37 ALA THR VAL ARG THR TYR SER CYS 0.448276 0.734375
38 ALA MET ARG VAL 0.446809 0.754386
39 PRO ALA THR ILE MET MET GLN ARG GLY ASN 0.445455 0.816667
40 ALA ARG THR MLY GLN THR ALA ARG TYR 0.442623 0.764706
41 ALA ARG THR GLU LEU TYR ARG SER LEU 0.439024 0.765625
42 ALA THR ALY ALA ALA ARG ALY SER ALA PRO 0.439024 0.735294
43 ALA ARG THR M3L GLN THR ALA DA2 LYS 0.435115 0.854839
44 ALA DA2 THR M3L GLN THR ALA ARG ALA 0.434426 0.854839
45 ARG ASP ALA ALA 0.433333 0.732143
46 ARG ARG ALA THR LYS MET NH2 0.432432 0.862069
47 ALA LYS ALA ILE ALA 0.431579 0.654545
48 ALA GLN THR ALA ARG ALY SER THR 0.431034 0.877193
49 ALA ARG LYS SEP THR GLY GLY LYS 0.429752 0.765625
50 GLU ALA GLN THR ARG LEU 0.428571 0.857143
51 GLN LEU ALA THR M3L ALA ALA ARG LYS SER 0.424779 0.868852
52 ASN ARG LEU LEU LEU THR GLY 0.424242 0.857143
53 ALA PRO ALA LEU ARG VAL VAL LYS 0.423077 0.818182
54 ALA ARG 0.419753 0.709091
55 LYS ALA ALA ARG M3L SER ALA 0.419643 0.83871
56 THR PRO ARG ARG SER MLZ SER ALA 0.418803 0.728571
57 HIS GLY ALA ALA ARG ALA GLU VAL HIS LEU 0.418182 0.767857
58 ARG GLU ARG SER PRO THR ARG 0.416667 0.652174
59 GLN THR ALA ARG M3L SER 0.413793 0.84127
60 PRO PRO LYS LYS LYS ARG LYS VAL 0.412371 0.796296
61 ASP LEU THR ARG PRO 0.412281 0.710145
62 ACE GLN THR ALA ARG PRK SER THR 0.410256 0.844828
63 LYS ARG ARG LYS SEP VAL 0.409524 0.746032
64 ALA MET ALA PRO ARG THR LEU LEU LEU 0.409449 0.742857
65 ALA ARG LYS ILE ASP ASN LEU ASP 0.408333 0.783333
66 ACE GLU ALA GLN THR ARG LEU 0.40708 0.875
67 ALA ARG M3L SER THR GLY GLY ALY 0.406504 0.815385
68 ALA ARG LYS LEU ASP 0.405941 0.821429
69 ACE GLN THR ALA ARG BTK SER THR 0.405172 0.877193
70 LYS GLN THR ALA ARG M3L SER THR GLY 0.403509 0.84127
71 ACE ALA ARG THR GLU VAL TYR NH2 0.403361 0.758065
72 ALA ARG MLZ SER THR GLY GLY ALY 0.403226 0.836066
73 ALA ARG MLY SER THR GLY GLY ALY 0.403226 0.8125
74 GLN ARG ALA THR LYS MET NH2 0.401709 0.862069
75 SER SER ARG LYS GLU TYR TYR ALA 0.4 0.703125
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback