-->
Receptor
PDB id Resolution Class Description Source Keywords
5BW4 2.1 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))- METHYLTRANSFERASE W203A MUTANT WITH COSUBSTRATE SAM FROM C ATENULISPORALES ACIDIPHILIA CATENULISPORA ACIDIPHILA METHYLTRANSFERASE RIBOSOME AMINOGLYCOSIDE RESISTANCE TRAN
Ref.: FUNCTIONAL DICHOTOMY IN THE 16S RRNA (M1A1408) METHYLTRANSFERASE FAMILY AND CONTROL OF CATALYTIC A VIA A NOVEL TRYPTOPHAN MEDIATED LOOP REORGANIZATION NUCLEIC ACIDS RES. V. 44 342 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:301;
B:301;
Valid;
Valid;
none;
none;
Kd = 68 uM
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5BW4 2.1 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))- METHYLTRANSFERASE W203A MUTANT WITH COSUBSTRATE SAM FROM C ATENULISPORALES ACIDIPHILIA CATENULISPORA ACIDIPHILA METHYLTRANSFERASE RIBOSOME AMINOGLYCOSIDE RESISTANCE TRAN
Ref.: FUNCTIONAL DICHOTOMY IN THE 16S RRNA (M1A1408) METHYLTRANSFERASE FAMILY AND CONTROL OF CATALYTIC A VIA A NOVEL TRYPTOPHAN MEDIATED LOOP REORGANIZATION NUCLEIC ACIDS RES. V. 44 342 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5BW4 Kd = 68 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 5BW4 Kd = 68 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5BW4 Kd = 68 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5BW4; Ligand: SAM; Similar sites found with APoc: 991
This union binding pocket(no: 1) in the query (biounit: 5bw4.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 1QAN SAH None
2 1RJD SAM None
3 2GDZ NAD None
4 2FKA BEF None
5 1PNO NAP None
6 1ZEI CRS None
7 4ZA2 NAD 0.790514
8 3GF4 FAD 1.1236
9 3GF4 UPG 1.1236
10 4ITU 1HS 1.1236
11 4ITU NAI 1.1236
12 2G5C NAD 1.1236
13 1T26 NAI 1.1236
14 1T26 GBD 1.1236
15 1LTH NAD 1.1236
16 6DUB SAH 1.35135
17 1L7N ALF 1.4218
18 1L7N AF3 1.4218
19 2IVD FAD 1.49813
20 1BDB NAD 1.49813
21 4D7E FAD 1.49813
22 3CTY FAD 1.49813
23 3Q3C NAD 1.49813
24 2XVM SAH 1.50754
25 5FUI APY 1.51515
26 2ZAT NAP 1.53846
27 5KOK SAH 1.87266
28 6GKV SAH 1.87266
29 4A6D SAM 1.87266
30 5KOK R9T 1.87266
31 5TS5 FAD 1.87266
32 1REO FAD 1.87266
33 5JCM ISD 1.87266
34 5JCM FAD 1.87266
35 5JCM NAD 1.87266
36 2PT9 2MH 1.87266
37 2I7C AAT 1.87266
38 3ZNN 4WL 1.87266
39 3ZNN FAD 1.87266
40 3U31 NAD 1.87266
41 6FDF SAH 1.87266
42 5JAQ NAI 1.87266
43 5W7R 9Z7 1.87266
44 9LDT NAD 1.87266
45 5W7R SAH 1.87266
46 9LDB NAD 1.87266
47 2B4R NAD 1.87266
48 1TDF NAP 1.87266
49 1TDF FAD 1.87266
50 2B4R AES 1.87266
51 1X7D ORN 1.87266
52 1X7D NAD 1.87266
53 2PT9 S4M 1.87266
54 4PLG NAI 1.87266
55 4PLG OXM 1.87266
56 5KOK S9T 1.87266
57 1U7T TDT 1.91571
58 1E3W NAD 1.91571
59 2XOC ADP 1.91571
60 1E6W NAD 1.92308
61 4A34 FUL 2.04082
62 1Q7B NAP 2.04918
63 6FC1 MGP 2.07254
64 1RJW ETF 2.24719
65 3A4T SFG 2.24719
66 1XDS SAM 2.24719
67 1QZZ SAM 2.24719
68 3LZW FAD 2.24719
69 3LZW NAP 2.24719
70 2YX1 SFG 2.24719
71 1COY FAD 2.24719
72 5TTJ FAD 2.24719
73 2IID PHE 2.24719
74 2IID FAD 2.24719
75 4DMG SAM 2.24719
76 4NTD FAD 2.24719
77 1XKQ NDP 2.24719
78 1COY AND 2.24719
79 3EVF GTA 2.24719
80 3EVF SAH 2.24719
81 1VL8 NAP 2.24719
82 1X87 NAD 2.24719
83 4N49 SAM 2.24719
84 6F7L FAD 2.24719
85 4U8P UDP 2.24719
86 4U8P FDA 2.24719
87 3NTD FAD 2.24719
88 1U2Z SAH 2.24719
89 3A4V NAD 2.24719
90 3FG2 FAD 2.24719
91 3A4V PYR 2.24719
92 2V3V MGD 2.24719
93 6BWL NAD 2.24719
94 2C5A NAD 2.24719
95 2C5A GDC 2.24719
96 1G0N NDP 2.24719
97 1G0N PHH 2.24719
98 1X14 NAD 2.24719
99 5GWT SIN 2.24719
100 5GWT NAD 2.24719
101 2PK3 A2R 2.24719
102 1Q9I FAD 2.27671
103 1Q9I TEO 2.27671
104 2AG8 NAP 2.28137
105 1ZEM NAD 2.29008
106 1QCI ADE 2.29008
107 3AFN NAP 2.32558
108 4NBW NAD 2.33463
109 1FK8 NAD 2.33463
110 4NBU NAI 2.4
111 2CFC NAD 2.4
112 1EDO NAP 2.45902
113 1QXA GLY GLY GLY 2.55319
114 2BZG SAH 2.58621
115 3FPF TNA 2.62172
116 3FPF MTA 2.62172
117 3A25 SAM 2.62172
118 1RP0 AHZ 2.62172
119 1RSG FAD 2.62172
120 6GAR FAD 2.62172
121 5MBX SP5 2.62172
122 5MBX FAD 2.62172
123 2GVC FAD 2.62172
124 3E1T FAD 2.62172
125 2YG3 FAD 2.62172
126 2GV8 FAD 2.62172
127 4MO2 FDA 2.62172
128 1VQW FAD 2.62172
129 4MO2 FAD 2.62172
130 1V59 NAD 2.62172
131 2QA1 FAD 2.62172
132 1RYI GOA 2.62172
133 5X68 FAD 2.62172
134 1RYI FAD 2.62172
135 4NTC FAD 2.62172
136 5GSN NAP 2.62172
137 5GSN FAD 2.62172
138 1V59 FAD 2.62172
139 5GSN MMZ 2.62172
140 2YY7 NAD 2.62172
141 1PS9 FAD 2.62172
142 6EL3 NAP 2.62172
143 3OND ADN 2.62172
144 3OND NAD 2.62172
145 1VKO NAD 2.62172
146 1DMR PGD 2.62172
147 1E5Q NDP 2.62172
148 1Z45 NAD 2.62172
149 4D86 ADP 2.62172
150 4PIO AVI 2.62172
151 1H2B NAJ 2.62172
152 1EK6 NAI 2.62172
153 4PIO SAH 2.62172
154 1EU1 MGD 2.62172
155 3IHG FAD 2.62172
156 1YFS ALA 2.62172
157 1EK6 UPG 2.62172
158 2A14 SAH 2.6616
159 1GEG NAD 2.73438
160 4RL4 PPV 2.83019
161 5O9F NAD 2.84091
162 5O9F 9ON 2.84091
163 2AG5 NAD 2.84553
164 1PR9 NAP 2.86885
165 3D3W NAP 2.86885
166 3TKA SAM 2.88184
167 5ZZ6 NAD 2.88462
168 5ZZ6 ADP 2.88462
169 2BOS GLA GAL GLC NBU 2.94118
170 2BOS GLA GAL GLC 2.94118
171 6CZ7 MGD 2.99145
172 4RDN 6MD 2.99401
173 5E9W SAH 2.99625
174 2EG5 SAH 2.99625
175 3L9W AMP 2.99625
176 3O7W SAM 2.99625
177 4YUW 4JU 2.99625
178 3L9W GSH 2.99625
179 4YUW S4M 2.99625
180 4USQ FAD 2.99625
181 3ICT FAD 2.99625
182 3ICS FAD 2.99625
183 4CNK FAD 2.99625
184 3ICR FAD 2.99625
185 4D79 ATP 2.99625
186 2R4J FAD 2.99625
187 2R4J 13P 2.99625
188 2RGJ FAD 2.99625
189 3LAD FAD 2.99625
190 5FJN BE2 2.99625
191 5FJN FAD 2.99625
192 3EVG SAH 2.99625
193 2P41 SAH 2.99625
194 2NVK FAD 2.99625
195 2ZWA SAH 2.99625
196 1ORR NAD 2.99625
197 4YAG NAI 2.99625
198 1FEC FAD 2.99625
199 3NT6 FAD 2.99625
200 3NKS FAD 2.99625
201 3NYC IAR 2.99625
202 3NYC FAD 2.99625
203 1R6D DAU 2.99625
204 1R6D NAD 2.99625
205 1VDC FAD 2.99625
206 3QWI CUE 2.99625
207 3QWI NAP 2.99625
208 2YVF NAD 2.99625
209 2YVF FAD 2.99625
210 5N6C NAD 2.99625
211 5MLR GRQ 2.99625
212 5MLR NAP 2.99625
213 1I2B NAD 2.99625
214 1I2B UPG 2.99625
215 1I2B USQ 2.99625
216 6GNC FAD 2.99625
217 3ICT ADP 2.99625
218 3OA2 NAD 2.99625
219 3ICS ADP 2.99625
220 1PJS NAD 2.99625
221 4RF2 NAP 2.99625
222 5NII FAD 2.99625
223 4J7U YTZ 2.99625
224 1Z6Z NAP 2.99625
225 4J7U NAP 2.99625
226 1UP7 NAD 2.99625
227 1WVG APR 2.99625
228 3BP1 GUN 2.99625
229 1BC5 SAH 2.99625
230 5MDH NAD 2.99625
231 4LEB THR THR THR THR THR THR THR 2.99625
232 2DTX BMA 3.0303
233 6CI9 NAP 3.0888
234 2AF6 BRU 3.10078
235 5J60 FAD 3.125
236 3FRH SAH 3.16206
237 5A9A UTP 3.29218
238 3VSE SAH 3.37079
239 3I53 SAH 3.37079
240 6BQ6 TER 3.37079
241 4ZCC FAD 3.37079
242 4ZCC NAI 3.37079
243 4USR FAD 3.37079
244 5ERG SAM 3.37079
245 3UOY NAP 3.37079
246 3UOY FAD 3.37079
247 5N0J FAD 3.37079
248 3QVP FAD 3.37079
249 3GDN FAD 3.37079
250 3GDN HBX 3.37079
251 3H8V ATP 3.37079
252 5BRT CH9 3.37079
253 5BRT FAD 3.37079
254 5WGR FAD 3.37079
255 6FP4 FAD 3.37079
256 6FP4 E1T 3.37079
257 5DF1 58X 3.37079
258 5DF1 NAP 3.37079
259 5NMX FAD 3.37079
260 5NMX NAP 3.37079
261 1Z3C SA8 3.37079
262 1DSS NAD 3.37079
263 3OJO NAD 3.37079
264 4Z0H NAD 3.37079
265 2UYQ SAM 3.37079
266 3O9Z AKG 3.37079
267 6DNT NAD 3.37079
268 2O4C NAD 3.37079
269 3O9Z NAD 3.37079
270 3V1Y NAD 3.37079
271 5UAO FAD 3.37079
272 5NA1 FAD 3.37079
273 5EZ7 FAD 3.37079
274 1UXG FUM 3.37079
275 1UXG NAD 3.37079
276 1HYH NAD 3.37079
277 3WLE NAD 3.37079
278 1LDN NAD 3.37079
279 2PX8 SAH 3.37079
280 1KOL NAD 3.37079
281 1GVF PGH 3.37079
282 1SC6 NAD 3.37079
283 2VTD LKM 3.37079
284 3DRW AMP 3.37079
285 2CUL FAD 3.44828
286 3CBG SAH 3.44828
287 2FK8 SAM 3.45912
288 2D5A COA 3.47222
289 4XZ3 COA 3.47826
290 4XYM COA 3.47826
291 4R6W PC 3.48837
292 4R6W SAH 3.48837
293 3FZG SAM 3.5
294 3MB5 SAM 3.52941
295 5YJ0 EF2 3.6036
296 5YJ1 6EL 3.6036
297 5YIZ EF2 3.6036
298 1Q3A NGH 3.63636
299 4BUZ OCZ 3.65854
300 4BUZ OAD 3.65854
301 2YVJ FAD 3.66972
302 1IM8 SAI 3.68852
303 5E1M PRO PRO LYS ARG ILE ALA 3.73444
304 5E1M SAH 3.73444
305 1D4D FAD 3.74532
306 3DMH SAM 3.74532
307 2DKH 3HB 3.74532
308 2DKH FAD 3.74532
309 2CDU FAD 3.74532
310 1FL2 FAD 3.74532
311 5G3U FDA 3.74532
312 1H82 FAD 3.74532
313 1NAA 6FA 3.74532
314 1NAA ABL 3.74532
315 4G5H UD7 3.74532
316 4G5H NAP 3.74532
317 1H82 GZZ 3.74532
318 4YNU FAD 3.74532
319 4YNU LGC 3.74532
320 5JCA FAD 3.74532
321 5JCA NDP 3.74532
322 2ZXI FAD 3.74532
323 4EUE NAI 3.74532
324 1KNR FAD 3.74532
325 1IY8 NAD 3.74532
326 5I39 FAD 3.74532
327 2CDU ADP 3.74532
328 5U8U FAD 3.74532
329 2JAH NDP 3.74532
330 5G3U ITW 3.74532
331 1O97 FAD 3.74532
332 3ZV6 4HB 3.74532
333 3ZV6 NAD 3.74532
334 4YAC NAI 3.74532
335 1O97 AMP 3.74532
336 1YXM ADE 3.74532
337 2E7Z MGD 3.74532
338 3DMH GMP 3.74532
339 3NJ4 NAD 3.74532
340 1R37 NAD 3.74532
341 2DFV NAD 3.74532
342 3NUG NAD 3.74532
343 1JA9 NDP 3.74532
344 1OC2 NAD 3.74532
345 1OC2 TDX 3.74532
346 1CF2 NAP 3.74532
347 4MP8 NAD 3.74532
348 4MP8 MLI 3.74532
349 1HKU NAD 3.74532
350 4PLT OXM 3.74532
351 2IZ1 ATR 3.74532
352 2CVQ NDP 3.74532
353 2YYY NAP 3.74532
354 4PLT NAI 3.74532
355 2DT5 NAD 3.79147
356 1G60 SAM 3.84615
357 4J4H NAI 3.861
358 4J4H 1J1 3.861
359 4JK3 NAD 3.861
360 5FFF 5XC 3.89105
361 5FFF NAP 3.89105
362 5M67 ADE 3.9666
363 5M67 NAD 3.9666
364 5M67 3D1 3.9666
365 4AZW SAM 4.11985
366 5JWC FAD 4.11985
367 2Q7V FAD 4.11985
368 4MOP 2H5 4.11985
369 3K7M FAD 4.11985
370 1NW5 SAM 4.11985
371 6ER9 FAD 4.11985
372 6ER9 NAP 4.11985
373 2Q1S NAI 4.11985
374 4BLW AMP 4.11985
375 3FPZ AHZ 4.11985
376 4RDH AMP 4.11985
377 5J5Z FAD 4.11985
378 1UWK URO 4.11985
379 1UWK NAD 4.11985
380 1XHC FAD 4.11985
381 5FUB SAH 4.11985
382 2JJQ SAH 4.11985
383 4TM3 FAD 4.11985
384 2RAB FAD 4.11985
385 2RAB NAD 4.11985
386 4C3Y FAD 4.11985
387 5BUK FAD 4.11985
388 4RDI ATP 4.11985
389 4C3Y ANB 4.11985
390 4ONQ SFG 4.11985
391 2Y6Q I7T 4.11985
392 2Y6Q FAD 4.11985
393 2WPF FAD 4.11985
394 4BJZ P3A 4.11985
395 4BJZ FAD 4.11985
396 1OBB NAD 4.11985
397 3GCZ SAM 4.11985
398 2F5Z FAD 4.11985
399 4ZRN NAD 4.11985
400 4ZRN UPG 4.11985
401 3T31 DCQ 4.11985
402 3T31 FAD 4.11985
403 2XVF FAD 4.11985
404 1GZ6 NAI 4.11985
405 2PZM UDP 4.11985
406 2PZM NAD 4.11985
407 1NV8 MEQ 4.11985
408 2RH4 EMO 4.11985
409 2WPF WPF 4.11985
410 1NV8 SAM 4.11985
411 6C4N NAP 4.11985
412 5GWX SAM 4.11985
413 5GWX SAR 4.11985
414 3ITJ FAD 4.11985
415 5XNC MTA 4.11985
416 3H9E NAD 4.11985
417 5JE8 NAD 4.11985
418 3WMX NAD 4.11985
419 5XLX SAH 4.11985
420 4BLW SAH 4.11985
421 4U7W NDP 4.11985
422 1U8X NAD 4.11985
423 5O4J 9KH 4.11985
424 5O4J SAH 4.11985
425 5O4J PJL 4.11985
426 5NUF NAD 4.11985
427 2HJR APR 4.11985
428 2A92 NAI 4.11985
429 1P3D UMA 4.11985
430 3CMC NAD 4.11985
431 2WK1 SAH 4.11985
432 1P31 EPU 4.11985
433 4XUC 43G 4.12844
434 4XUC SAM 4.12844
435 3WV8 ATP 4.12844
436 1H5Q NAP 4.15094
437 3VC1 SAH 4.16667
438 3VC1 GST 4.16667
439 3UZO GLU 4.18994
440 1H0H MGD 4.20561
441 1JG3 ADN 4.25532
442 1VKF CIT 4.25532
443 3TN7 NJP 4.28016
444 1LSS NAD 4.28571
445 3RJ5 NAD 4.33071
446 1VM6 NAD 4.38596
447 3IWD M2T 4.41176
448 2JAP NDP 4.45344
449 4X60 3XV 4.49438
450 4X60 SFG 4.49438
451 5FA5 MTA 4.49438
452 4JNA FAD 4.49438
453 3HDY GDU 4.49438
454 3HDY FDA 4.49438
455 5BJX UDP 4.49438
456 5BJX NAD 4.49438
457 5EEH P9P 4.49438
458 5EEH SAH 4.49438
459 3G5S FAD 4.49438
460 3HDY FAD 4.49438
461 1PN0 FAD 4.49438
462 1PN0 IPH 4.49438
463 3AB1 FAD 4.49438
464 4X9M FAD 4.49438
465 3X0V FAD 4.49438
466 2OBF F83 4.49438
467 2OBF SAH 4.49438
468 5Z75 NAD 4.49438
469 5FEU NAP 4.49438
470 2XVE FAD 4.49438
471 1BXK NAD 4.49438
472 2WET FAD 4.49438
473 3VYW SAM 4.49438
474 3NTA FAD 4.49438
475 3GRU AMP 4.49438
476 4MIG G3F 4.49438
477 2Q1W NAD 4.49438
478 1ZBQ NAD 4.49438
479 5UR0 NAD 4.49438
480 1YKJ FAD 4.49438
481 1YKJ PHB 4.49438
482 3RIY NAD 4.49438
483 6EQS BV8 4.49438
484 1NVM NAD 4.49438
485 3GGO NAI 4.49438
486 5Y1G NAD 4.49438
487 5Y1G AKB 4.49438
488 5Z20 NAI 4.49438
489 5EJ2 NAD 4.49438
490 5A7Y SAH 4.49438
491 5KJW 53C 4.49438
492 3HB5 NAP 4.49438
493 5TOW ADN 4.49438
494 5TOW NAI 4.49438
495 2ZJ1 ARJ 4.49438
496 2ZJ1 NAD 4.49438
497 3LU1 NAD 4.49438
498 4RPL FAD 4.51128
499 4RPL 3UC 4.51128
500 3HVJ 705 4.52489
501 1A8R GTP 4.52489
502 5E8J SAH 4.54545
503 3DXY SAM 4.58716
504 3BGD SAH 4.61538
505 3BGD PM6 4.61538
506 3C3Y SAH 4.64135
507 2PXX SAH 4.65116
508 3OID NDP 4.65116
509 4MBY BGC SIA GAL 4.67626
510 5OVK NDP 4.6875
511 1JQ3 AAT 4.72973
512 6BJO DUY 4.8
513 1WY7 SAH 4.83092
514 6ARJ BW4 4.86891
515 6ARJ SAH 4.86891
516 5DX8 SFG 4.86891
517 2EJU SAH 4.86891
518 1QO8 FAD 4.86891
519 3PT9 SAH 4.86891
520 3ELW SAM 4.86891
521 3ELW GP3 4.86891
522 4II2 ATP 4.86891
523 1ZQ9 SAM 4.86891
524 4EIP FAD 4.86891
525 5DX1 SFG 4.86891
526 5DXA SFG 4.86891
527 5HSA FAS 4.86891
528 1GTE FAD 4.86891
529 1V6A TRE 4.86891
530 1O94 ADP 4.86891
531 4ZVV NAD 4.86891
532 1DJN ADP 4.86891
533 3SSO SAH 4.86891
534 4ZVV GN0 4.86891
535 6FHO FAD 4.86891
536 6H3O FAD 4.86891
537 2FR1 NDP 4.86891
538 6CEP NAD 4.86891
539 5K4W NAI 4.86891
540 5K4W THR 4.86891
541 3SJU NDP 4.86891
542 1AE1 NAP 4.86891
543 3P9C SAH 4.86891
544 1OMO NAD 4.86891
545 2Q28 ADP 4.86891
546 3RKR NAP 4.96183
547 1Q0S SAH 5.01931
548 4NYT PC 5.06912
549 2NXE SAM 5.11811
550 4QTU SAM 5.18518
551 3G89 SAM 5.22088
552 1M2K APR 5.22088
553 4IWN GEK 5.24017
554 1G55 SAH 5.24345
555 5MW4 5JU 5.24345
556 3QOX SAH 5.24345
557 2EFJ SAH 5.24345
558 3A27 SAM 5.24345
559 5TWB FAD 5.24345
560 4D04 FAD 5.24345
561 4D04 NAP 5.24345
562 3Q87 SAM 5.24345
563 3QJ4 FAD 5.24345
564 6F97 FAD 5.24345
565 4YRY NAD 5.24345
566 4YRY FAD 5.24345
567 2NPX FAD 5.24345
568 2NPX NAD 5.24345
569 5Y77 FAD 5.24345
570 2VVM FAD 5.24345
571 2VVL FAD 5.24345
572 5FWA J7C 5.24345
573 5A3B APR 5.24345
574 3CIF NAD 5.24345
575 4FC7 NAP 5.24345
576 4FC7 COA 5.24345
577 3O03 NAP 5.24345
578 3CIF G3H 5.24345
579 1KEW NAD 5.24345
580 1GUZ NAD 5.24345
581 1TMO 2MD 5.24345
582 1G6O ADP 5.24345
583 5GT9 NAP 5.32319
584 3L4S NAD 5.35714
585 3L4S 3PG 5.35714
586 1OAA OAA 5.40541
587 3IT7 TLA 5.49451
588 2HMT NAI 5.55556
589 3CH6 311 5.59441
590 3CH6 NAP 5.59441
591 5X62 SAH 5.61798
592 4J36 1HR 5.61798
593 1KPG SAH 5.61798
594 4J36 FAD 5.61798
595 5MIT FAD 5.61798
596 5MIT NAP 5.61798
597 3C6K SPD 5.61798
598 1XHL NDP 5.61798
599 2ZIF SAM 5.61798
600 3OZ2 FAD 5.61798
601 3C6K MTA 5.61798
602 3F8D FAD 5.61798
603 4DCM SAM 5.61798
604 1UDB NAD 5.61798
605 1UDB UFG 5.61798
606 3U4C NDP 5.61798
607 5J7X FAD 5.61798
608 5ZBC FAD 5.61798
609 1MV8 NAD 5.61798
610 1V5F TPP 5.61798
611 1V5F FAD 5.61798
612 4Y9D NAI 5.61798
613 5ME4 HP4 5.61798
614 3WDM ADN 5.74713
615 4CQM NAP 5.74713
616 4YKG FAD 5.75816
617 4YKG NAD 5.75816
618 2HQM FAD 5.84551
619 2Q46 NAP 5.92885
620 4M37 SAH 5.99251
621 5W7K SAH 5.99251
622 4M38 SAH 5.99251
623 5W7M SAH 5.99251
624 2Z3Y F2N 5.99251
625 2GAG NAD 5.99251
626 1Q1R FAD 5.99251
627 1L1E SAH 5.99251
628 4HA6 FAD 5.99251
629 4FWE FAD 5.99251
630 5EB4 FAD 5.99251
631 2C7G FAD 5.99251
632 2C7G ODP 5.99251
633 5O42 BGC 5.99251
634 5O42 NAD 5.99251
635 5O42 9JW 5.99251
636 4FZV SAM 5.99251
637 5THY SAH 5.99251
638 4Z24 FAD 5.99251
639 2GAG FAD 5.99251
640 2GAG FOA 5.99251
641 2RGO FAD 5.99251
642 4J56 FAD 5.99251
643 5YU3 NAD 5.99251
644 5YU3 PRO 5.99251
645 4JJF FE9 5.99251
646 4JJF N2I 5.99251
647 1YBH FAD 5.99251
648 5THQ NDP 5.99251
649 3V1U NAD 5.99251
650 5AHO TLA 5.99251
651 1K3T BRZ 5.99251
652 1LLU NAD 5.99251
653 3EYA FAD 5.99251
654 5LW0 AR6 6.06061
655 2AE2 PTO 6.15385
656 2AE2 NAP 6.15385
657 1R18 SAH 6.1674
658 1N13 AG2 6.19469
659 2PWY SAH 6.20155
660 4M52 FAD 6.22318
661 4M52 M52 6.22318
662 2A8X FAD 6.25
663 2VPY MGD 6.32411
664 1TPY SAH 6.36704
665 1YQZ FAD 6.36704
666 2Q0L FAD 6.36704
667 4AP3 FAD 6.36704
668 4AP3 NAP 6.36704
669 1GPE FAD 6.36704
670 2GMH FAD 6.36704
671 1WG8 SAM 6.36704
672 5JJR SAH 6.36704
673 2BGM NAJ 6.36704
674 2RGH FAD 6.36704
675 1XG5 NAP 6.36704
676 1GR0 NAD 6.36704
677 4YT4 FE9 6.36704
678 5YB7 FAD 6.36704
679 5YB7 ORN 6.36704
680 2B9W FAD 6.36704
681 5Z2L NDP 6.36704
682 3DUV KDO 6.36704
683 4X7Y SAH 6.36704
684 2F1K NAP 6.36704
685 2NYA MGD 6.36704
686 2BD0 NAP 6.55738
687 2XYQ SAH 6.55738
688 5OFW 9TW 6.72646
689 3DUW SAH 6.72646
690 3X0D SAH 6.74157
691 3MCT SAH 6.74157
692 4Y30 49L 6.74157
693 2O07 SPD 6.74157
694 3MAG SAH 6.74157
695 2O07 MTA 6.74157
696 1YY5 FAD 6.74157
697 1KPH SAH 6.74157
698 2E5V FAD 6.74157
699 5ICE 2H4 6.74157
700 5ICE SAH 6.74157
701 3AYI HCI 6.74157
702 3AYI FAD 6.74157
703 2DPM SAM 6.74157
704 6B92 SAH 6.74157
705 1SB8 NAD 6.74157
706 1SB8 UD2 6.74157
707 5HXI FAD 6.74157
708 1XSE NDP 6.74157
709 5HXI 5HN 6.74157
710 4YDD MGD 6.74157
711 4YDD MD1 6.74157
712 3VPH OXM 6.74157
713 2VYN NAD 6.74157
714 3VPH NAD 6.74157
715 3GFB NAD 6.74157
716 1MUU NAD 6.74157
717 4Y30 SAH 6.74157
718 1G8K MGD 6.76692
719 3Q9N COA 6.96203
720 3A28 NAD 6.97674
721 5OJ7 AR6 6.99301
722 4OBW SAM 7.00389
723 5YJI 8WO 7.04225
724 5YJI SAH 7.04225
725 5WP4 SAH 7.11611
726 4GQB 0XU 7.11611
727 5WP5 SAH 7.11611
728 4OPC FDA 7.11611
729 4OPC PGT 7.11611
730 3G2O SAM 7.11611
731 3LXD FAD 7.11611
732 1GET NAP 7.11611
733 1GET FAD 7.11611
734 1EFV FAD 7.11611
735 1EFV AMP 7.11611
736 2IXB A2G 7.11611
737 2IXB NAD 7.11611
738 4AT0 FAD 7.11611
739 1V8B NAD 7.11611
740 3ML1 MGD 7.11611
741 3M6W SAM 7.11611
742 5NUE NAD 7.11611
743 3AXB PRO 7.14286
744 3AXB FAD 7.14286
745 3QXV MTX 7.14286
746 6GFK SAH 7.17131
747 3JUC PCA 7.18954
748 2EWM NAD 7.22892
749 3GU3 SAH 7.39437
750 3OFK SAH 7.40741
751 1UAY ADN 7.43802
752 5Y8L NAD 7.45763
753 5Y8L HUI 7.45763
754 3KLJ FAD 7.49064
755 1C0I FAD 7.49064
756 1C0I BE2 7.49064
757 5EOW FAD 7.49064
758 6F9Q NAD 7.49064
759 1RM0 NAI 7.49064
760 1RM0 D6P 7.49064
761 1U1I NAD 7.49064
762 3H5N ATP 7.49064
763 6DEN TP9 7.49064
764 6DEN G8A 7.49064
765 6DEN FAD 7.49064
766 5WS9 AMP 7.49064
767 1DL5 SAH 7.49064
768 5F7J ADE 7.49064
769 3DAG FEG 7.49064
770 5YEC ATP 7.49064
771 5WUW NAP 7.49064
772 5L95 AMP 7.5
773 3GWZ SAH 7.58808
774 3GXO SAH 7.58808
775 5N53 8NB 7.69231
776 1DJL NAP 7.72947
777 3TLJ SAH 7.86517
778 5MPT SAH 7.86517
779 5ZYN FAD 7.86517
780 4EMI FAD 7.86517
781 4EMI NAD 7.86517
782 1LVL NAD 7.86517
783 1NJR XYL 7.86517
784 1LVL FAD 7.86517
785 1J0X NAD 7.86517
786 4OM8 NAD 7.86517
787 4UCI SAM 7.86517
788 5DN9 NAD 7.86517
789 3ABI NAD 7.86517
790 2PHX MAN MAN 7.93651
791 1UKG MMA 7.93651
792 1Q8V MAN MAN 7.93651
793 2GND MAN 7.93651
794 1Q8Q MAN MMA 7.93651
795 1Q8O MAN MMA 7.93651
796 2GNB MAN 7.93651
797 1Q8S MAN MMA 7.93651
798 2GNM MAN 7.93651
799 2GN3 MMA 7.93651
800 2IVF MGD 7.94393
801 5ZW3 SAH 8
802 1NFQ NAI 8.07692
803 5FTW SAH 8.20312
804 4C4A SAH 8.2397
805 1ELI PYC 8.2397
806 4K5S FAD 8.2397
807 4K5S PM0 8.2397
808 1KYQ NAD 8.2397
809 4IV9 FAD 8.2397
810 2V6G NAP 8.2397
811 1BW9 NAD 8.2397
812 2CDC XYP 8.2397
813 2CDC NAP 8.2397
814 2CDC XYS 8.2397
815 2OOR TXP 8.2397
816 4LH7 1X8 8.2397
817 1RPN NDP 8.2397
818 1NM5 NAP 8.2397
819 1NM5 NAD 8.2397
820 1RKX NAD 8.2397
821 4GLL NAD 8.2397
822 3GDH SAH 8.29876
823 1J5P NAD 8.3004
824 2WA2 SAM 8.33333
825 3FUU ADN 8.48709
826 4POO SAM 8.5
827 3GEG NAD 8.50202
828 3QV1 NAD 8.53659
829 2JHP SAH 8.61423
830 3GD4 NAD 8.61423
831 3GD4 FAD 8.61423
832 3UCL CYH 8.61423
833 3UCL FAD 8.61423
834 3UCL NAP 8.61423
835 4BV6 FAD 8.61423
836 1Y8Q ATP 8.61423
837 4RSL FAD 8.61423
838 3WGT QSC 8.61423
839 3WGT FAD 8.61423
840 4K26 SFF 8.61423
841 4K26 NDP 8.61423
842 3QFA FAD 8.62069
843 1D4O NAP 8.69565
844 3SJ7 NDP 8.73016
845 5OOH 9ZZ 8.73786
846 5OOH NAP 8.73786
847 5K0A FAD 8.78788
848 5KMS NAD 8.98876
849 5KOX RFP 8.98876
850 5KOX FAD 8.98876
851 1BZL GCG 8.98876
852 1BZL FAD 8.98876
853 5KMS FAD 8.98876
854 6F3M NAD 8.98876
855 1VJT NAD 8.98876
856 5OJI ISN 9.23077
857 5OJI NAP 9.23077
858 1I1N SAH 9.29204
859 5MGZ SAH 9.32203
860 1JNR FAD 9.33333
861 1MO9 KPC 9.3633
862 1MO9 FAD 9.3633
863 1DLJ NAI 9.3633
864 1EZ4 NAD 9.3633
865 5WKC FAD 9.3633
866 1T9D FAD 9.3633
867 4CS9 AMP 9.52381
868 4URF NAD 9.67742
869 5CUQ NSC 9.73783
870 4TXI FAD 9.73783
871 2BRY FAD 9.73783
872 5UAV NDP 9.73783
873 4KGD FAD 9.73783
874 4KGD TDP 9.73783
875 5UAV TFB 9.73783
876 1J49 NAD 9.73783
877 3RFV NAI 9.73783
878 2F2H XTG 9.73783
879 3AD8 NAD 10.101
880 3AD8 PYC 10.101
881 3AD8 FAD 10.101
882 2AOT SAH 10.1124
883 1JQD HSM 10.1124
884 1KYZ SAH 10.1124
885 5BVA FAD 10.1124
886 1GY8 NAD 10.1124
887 1JQD SAH 10.1124
888 4D5G FAD 10.1124
889 4D5G TPP 10.1124
890 1KYZ FER 10.1124
891 3VZS NAP 10.1167
892 3LCC SAH 10.2128
893 4FN4 NAD 10.2362
894 3RNM FAD 10.3448
895 4GKV NAD 10.4167
896 4GUT FAD 10.4839
897 4XQC NAD 10.4869
898 4XQC 13D 10.4869
899 6GAS FAD 10.4869
900 2JB2 FAD 10.4869
901 2JB2 PHE 10.4869
902 4XBA GMP 10.4869
903 1W8D NAP 10.596
904 1W73 NAP 10.596
905 5DM1 SAH 10.8614
906 5DM1 5D7 10.8614
907 3CGB FAD 10.8614
908 5THZ SAH 10.8614
909 4UP3 FAD 10.8614
910 1SZD APR 10.8614
911 2OD9 A1R NCA 10.8614
912 2QQF A1R 10.8614
913 1EJ0 SAM 11.1111
914 1ZK4 NAP 11.1554
915 1ZK4 AC0 11.1554
916 2VT3 ATP 11.1628
917 4M73 SAH 11.236
918 4M73 M72 11.236
919 3NDJ JHZ 11.236
920 3NDJ SAH 11.236
921 5MZI FYK 11.236
922 5MZI FAD 11.236
923 6AIN FAD 11.236
924 4HXY NDP 11.236
925 6F3N ADN 11.236
926 6F3N NAD 11.236
927 1SOW NAD 11.2805
928 1S7G NAD 11.4625
929 1S7G APR 11.4625
930 1W6U NAP 11.5894
931 3TKY SAH 11.6105
932 6D6Y SAH 11.6105
933 2IV2 MGD 11.6105
934 1RLZ NAD 11.6105
935 3S5W FAD 11.6105
936 2IV2 2MD 11.6105
937 5ODQ FAD 11.9565
938 1E6E FAD 11.985
939 1E1M NAP 11.985
940 1E1M FAD 11.985
941 1ZK7 FAD 11.985
942 2AQJ TRP 11.985
943 2AQJ FAD 11.985
944 3S1S SAH 11.985
945 4XFR CIT 11.985
946 5DLY 5D7 12.0301
947 5DLY SAH 12.0301
948 2WSB NAD 12.2047
949 1I8T FAD 12.3596
950 4REP FAD 12.3596
951 1N2X SAM 12.7341
952 1XCL SAH 12.766
953 1KQF MGD 13.1086
954 4KWI NAP 13.308
955 3CGD COA 13.8577
956 3CGD FAD 13.8577
957 3CGD NAD 13.8577
958 5T2U NAP 14.1129
959 5TVF CGQ 14.1176
960 5VN0 FAD 14.2322
961 5VN0 NAI 14.2322
962 3SQP FAD 14.2322
963 5YF1 8V0 14.2322
964 5YF1 SFG 14.2322
965 3GMB FAD 14.9813
966 1P1C SAH 15.0754
967 4L2I FAD 15.2091
968 3JWH SAH 15.6682
969 4B63 NAP 16.1049
970 4B63 FAD 16.1049
971 4B63 ORN 16.1049
972 4JDR FAD 16.1049
973 2VDV SAM 16.2602
974 5OC1 FAD 16.4794
975 3EGI ADP 16.9903
976 5HJM MTA 17.9775
977 4DSG FAD 17.9775
978 4DSG UDP 17.9775
979 2FAV APR 18.3333
980 2VHW NAI 18.3521
981 5M58 SAH 19.1304
982 2GN4 NDP 19.8502
983 2GN4 UD1 19.8502
984 5DWQ SFG 20
985 5DX0 SFG 20
986 4YSX FAD 21.3483
987 1VE3 SAM 21.5859
988 5D4V SAH 23.97
989 4EMJ FAD 36.4486
990 4HSU FAD 36.6667
991 4GUS FAD 42.8571
Pocket No.: 2; Query (leader) PDB : 5BW4; Ligand: SAM; Similar sites found with APoc: 96
This union binding pocket(no: 2) in the query (biounit: 5bw4.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 6BOC EU7 None
2 4FGC PQ0 1.21212
3 2CBZ ATP 1.26582
4 5YSS NAD 1.5625
5 3KU0 ADE 1.59363
6 5ZXD ATP 1.8315
7 6GNA FAD 1.87266
8 4FRZ ADP 1.87266
9 5H4S