Receptor
PDB id Resolution Class Description Source Keywords
5BR7 1.95 Å EC: 5.4.99.9 STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM CORYNEBACTERIUM DIPHTHERIAE IN COMPLEX WITH CITRATE ION CORYNEBACTERIUM DIPHTHERIAE (STRAIN AT/ NCTC 13129 / BIOTYPE GRAVIS) UDP-GALACTOPYRANOSE MUTASE CORYNEBACTERIUM DIPHTHERIAE GALACTOFURANOSE GALACTOPYRANOSE CITRATE FAD SODIUM IONISOMERASE
Ref.: CONFORMATIONAL CONTROL OF UDP-GALACTOPYRANOSE MUTAS INHIBITION. BIOCHEMISTRY V. 56 3983 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:404;
A:405;
A:403;
A:402;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
IPA A:410;
A:409;
A:408;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
60.095 C3 H8 O CC(C)...
NA A:406;
A:407;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
FLC A:411;
Valid;
none;
submit data
189.1 C6 H5 O7 C(C(=...
FAD A:401;
Valid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5BR7 1.95 Å EC: 5.4.99.9 STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM CORYNEBACTERIUM DIPHTHERIAE IN COMPLEX WITH CITRATE ION CORYNEBACTERIUM DIPHTHERIAE (STRAIN AT/ NCTC 13129 / BIOTYPE GRAVIS) UDP-GALACTOPYRANOSE MUTASE CORYNEBACTERIUM DIPHTHERIAE GALACTOFURANOSE GALACTOPYRANOSE CITRATE FAD SODIUM IONISOMERASE
Ref.: CONFORMATIONAL CONTROL OF UDP-GALACTOPYRANOSE MUTAS INHIBITION. BIOCHEMISTRY V. 56 3983 2017
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5EQF - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5BR7 - FLC C6 H5 O7 C(C(=O)[O-....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 1V0J - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4RPL - 3UC C15 H20 F4 N2 O15 P2 C1=CN(C(=O....
3 4RPJ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4RPG - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 5EQF - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 5BR7 - FLC C6 H5 O7 C(C(=O)[O-....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1V0J - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4RPL - 3UC C15 H20 F4 N2 O15 P2 C1=CN(C(=O....
3 4RPJ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4RPG - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 1I8T - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 4MO2 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 5EQF - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
8 5BR7 - FLC C6 H5 O7 C(C(=O)[O-....
9 3HE3 - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
10 3HDQ Kd = 220 uM GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
11 3HDY Kd = 66 uM GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
12 1WAM - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
13 2BI8 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
14 3INR - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
15 3GF4 Kd = 750 uM UPG C15 H24 N2 O17 P2 C1=CN(C(=O....
16 2BI7 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FLC; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 FLC 1 1
2 FE CIT 0.95 0.875
Ligand no: 2; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5BR7; Ligand: FAD; Similar sites found: 297
This union binding pocket(no: 1) in the query (biounit: 5br7.bio2) has 60 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4BV6 FAD 0.00001605 0.40849 1.27226
2 4ONQ SFG 0.03264 0.40924 1.40056
3 2FR1 NDP 0.002598 0.42766 1.52672
4 1P31 EPU 0.03761 0.40617 1.52672
5 1YQZ FAD 0.0004101 0.40027 1.52672
6 1F3L SAH 0.005164 0.43896 1.55763
7 3U31 NAD 0.0139 0.41892 1.72414
8 5XVQ SAH 0.01986 0.40916 1.76056
9 1N4W FAD 0.000002871 0.43198 1.78117
10 1CER NAD 0.002113 0.44454 1.81269
11 1GZ6 NAI 0.01294 0.40154 1.88088
12 3NT6 FAD 0.00001031 0.40651 1.91638
13 2PV7 NAD 0.004697 0.42686 2.01342
14 5EVY FAD 0.0007694 0.4737 2.03562
15 1XDS SAM 0.01031 0.44435 2.13904
16 1QZZ SAM 0.01358 0.43811 2.13904
17 1PN0 IPH 0.00002249 0.42021 2.29008
18 1PN0 FAD 0.00001994 0.41961 2.29008
19 3GFB NAD 0.00706 0.41928 2.29008
20 2FKA BEF 0.005953 0.46044 2.32558
21 5ENZ UDP 0.01912 0.42379 2.33766
22 5FTW SAH 0.02306 0.41122 2.34375
23 3F8D FAD 0.000002713 0.47335 2.47678
24 3WMX NAD 0.007159 0.4215 2.51397
25 2GV8 FAD 0.000001277 0.55232 2.54453
26 4EMI NAD 0.00004346 0.42981 2.54453
27 2GV8 NDP 0.0122 0.41629 2.54453
28 2GVC FAD 0.0000009843 0.41543 2.54453
29 4EMI FAD 0.00000516 0.41485 2.54453
30 5JCM FAD 0.0001714 0.4159 2.66075
31 5JCM ISD 0.0001825 0.4159 2.66075
32 5JCM NAD 0.0001934 0.41517 2.66075
33 3MQ2 SAH 0.0435 0.4057 2.75229
34 2CVZ NDP 0.01318 0.40994 2.76817
35 4DPL NAP 0.006505 0.41605 2.78552
36 5VN0 FAD 0.00002268 0.49064 2.79898
37 5VN0 NAI 0.0002055 0.41542 2.79898
38 1NPD NAD 0.01546 0.41165 2.79898
39 3LXD FAD 0.000007197 0.40413 2.79898
40 2JAP NDP 0.01266 0.40193 2.83401
41 1VQW FAD 0.000002611 0.40581 2.84464
42 2V3A FAD 0.000005273 0.4124 2.86458
43 5E8J SAH 0.001988 0.48158 2.88462
44 1EQ2 NAP 0.01293 0.40578 2.90323
45 4O0L NDP 0.008707 0.4086 2.90909
46 1E3I CXF 0.006579 0.40326 2.92553
47 3ITJ FAD 0.000006383 0.43747 2.95858
48 5N53 8NB 0.03654 0.43168 3.07692
49 4OBW SAM 0.004558 0.45139 3.11284
50 5HJM MTA 0.003427 0.45391 3.125
51 1GEG NAD 0.002513 0.4332 3.125
52 3EGV SAH 0.01011 0.4377 3.14961
53 2BKX F6R 0.01518 0.43558 3.30579
54 4DMG SAM 0.005442 0.46299 3.30789
55 5MQ6 NDP 0.003625 0.44299 3.30789
56 4MIG G3F 0.000005634 0.43504 3.30789
57 3GDN HBX 0.00001279 0.43166 3.30789
58 3GDN FAD 0.000004328 0.42758 3.30789
59 2DT5 NAD 0.00275 0.43415 3.31754
60 3ZNN FAD 0.0001055 0.41447 3.45821
61 3ZNN 4WL 0.0001055 0.41447 3.45821
62 3WGT FAD 0.00003784 0.41405 3.45821
63 3WGT QSC 0.00005301 0.41176 3.45821
64 4UP3 FAD 0.0000005721 0.44312 3.50318
65 1FL2 FAD 0.0000001739 0.45256 3.54839
66 1Q1R FAD 0.000005396 0.5171 3.56234
67 4G74 FAD 0.00002886 0.49292 3.56234
68 4G74 UQ5 0.0001528 0.43865 3.56234
69 2Q1W NAD 0.0008462 0.44463 3.6036
70 1YXM ADE 0.002652 0.49417 3.63036
71 1P77 ATR 0.003305 0.48945 3.67647
72 1NYT NAP 0.02175 0.40263 3.69004
73 1D1T NAD 0.006775 0.41089 3.75335
74 2IVD FAD 0.00000001421 0.61862 3.81679
75 5HSA FAS 0.00001612 0.41033 3.81679
76 4ZRN NAD 0.0009656 0.43983 3.84615
77 5F2T PLM 0.0435 0.40044 3.8961
78 2I3G NAP 0.01219 0.40261 3.97727
79 2R4J FAD 0.00004996 0.41668 3.99202
80 2R4J 13P 0.00004996 0.41668 3.99202
81 4YCA NDP 0.00175 0.4481 4.08163
82 4K28 NAD 0.002682 0.44291 4.08922
83 3GD4 NAD 0.00006422 0.43522 4.10959
84 3GD4 FAD 0.0001004 0.41611 4.10959
85 1D4D FAD 0.0000001727 0.46412 4.1958
86 5TUF FAD 0.000007157 0.53063 4.3257
87 5TUF TDC 0.000102 0.42434 4.3257
88 2OM2 GDP 0.02925 0.40888 4.3257
89 4J36 1HR 0.00005059 0.40057 4.3257
90 2B9W FAD 0.00000003875 0.50946 4.48113
91 3QVP FAD 0.00000285 0.43262 4.58015
92 4Z24 FAD 0.000002307 0.43226 4.58015
93 2I7C AAT 0.004935 0.41211 4.58015
94 4REP FAD 0.00000001572 0.47756 4.64646
95 4EMJ FAD 0.00001465 0.40607 4.6729
96 1Q9I TEO 0.000002223 0.46117 4.72855
97 1Q9I FAD 0.000002223 0.46117 4.72855
98 4CS9 AMP 0.01366 0.45739 4.7619
99 3FG2 FAD 0.00002062 0.50858 4.83461
100 4YRY NAD 0.0000008988 0.46583 4.83461
101 4YRY FAD 0.0000003026 0.45408 4.83461
102 5BVA FAD 0.000001135 0.44487 4.83461
103 3UCL NAP 0.0001121 0.42437 4.83461
104 3UCL CYH 0.00009974 0.42349 4.83461
105 3UCL FAD 0.00009974 0.42349 4.83461
106 5EB4 FAD 0.000003977 0.42326 4.83461
107 4HA6 FAD 0.000007511 0.42279 4.83461
108 3EGI ADP 0.0008466 0.52308 4.85437
109 5H81 NAP 0.005493 0.43771 4.88432
110 1XHC FAD 0.0000006727 0.42789 4.90463
111 1H5Q NAP 0.006098 0.41494 4.90566
112 5JE8 NAD 0.005239 0.43006 4.96689
113 3A28 NAD 0.006664 0.41562 5.03876
114 4NTC FAD 0.000001348 0.43648 5.07463
115 1MO9 FAD 0.0000009311 0.4931 5.08906
116 1MO9 KPC 0.000001349 0.4891 5.08906
117 4OPC PGT 0.00002284 0.46494 5.08906
118 4OPC FDA 0.00001779 0.46417 5.08906
119 1GPE FAD 0.000003478 0.43553 5.08906
120 5MZI FAD 0.00003408 0.43129 5.08906
121 5MZI FYK 0.00003865 0.43129 5.08906
122 2E5V FAD 0.0000058 0.42546 5.08906
123 3NTD FAD 0.000004373 0.41562 5.08906
124 5JWC FAD 0.00001139 0.40063 5.08906
125 2GND MAN 0.02859 0.43612 5.15873
126 2PHT MAN MAN MAN 0.03815 0.43018 5.15873
127 2GND MAN MMA 0.0368 0.42958 5.15873
128 4RDH AMP 0.000769 0.4982 5.20833
129 3AB1 FAD 0.000001047 0.43491 5.27778
130 1VE3 SAM 0.008518 0.43806 5.28634
131 1W73 NAP 0.00355 0.44041 5.29801
132 1N2X SAM 0.01217 0.41893 5.31561
133 2A8X FAD 0.0000004072 0.5368 5.34351
134 2Z3Y F2N 0.000000004344 0.50524 5.34351
135 1E1M NAP 0.000001201 0.4624 5.34351
136 1E1M FAD 0.000001201 0.4624 5.34351
137 1E6E FAD 0.000000168 0.44243 5.34351
138 4YNU LGC 0.00001026 0.42988 5.34351
139 4YNU FAD 0.000006435 0.42712 5.34351
140 3NTA FAD 0.000005333 0.4136 5.34351
141 1YKJ PHB 0.0003148 0.4075 5.34351
142 1YKJ FAD 0.0003148 0.4075 5.34351
143 4TM3 FAD 0.000456 0.40657 5.34351
144 1REO FAD 0.001401 0.40082 5.34351
145 3VYW SAM 0.00468 0.44409 5.51948
146 5TS5 FAD 0.000000007277 0.60603 5.59796
147 2NPX FAD 0.000002892 0.52725 5.59796
148 3CGB FAD 0.000008521 0.50966 5.59796
149 2JB2 PHE 0.0000001028 0.46435 5.59796
150 2JB2 FAD 0.0000000868 0.4634 5.59796
151 2NPX NAD 0.00002216 0.44584 5.59796
152 1GTE FAD 0.000025 0.44022 5.59796
153 1KNR FAD 0.000003797 0.4246 5.59796
154 4TXI FAD 0.000001562 0.40574 5.59796
155 1ZBQ NAD 0.01079 0.40272 5.59796
156 4D86 ADP 0.04099 0.40171 5.59796
157 1YY5 FAD 0.00000002381 0.48883 5.65302
158 4YSX FAD 0.00000318 0.42655 5.76923
159 5G3U FDA 0.0000001621 0.45102 5.85242
160 4M52 FAD 0.0000004537 0.45052 5.85242
161 5G3U ITW 0.000001209 0.44593 5.85242
162 3E1T FAD 0.000001208 0.44246 5.85242
163 1FEC FAD 0.000004713 0.43548 5.85242
164 5BUK FAD 0.0000089 0.42189 5.85242
165 4JNA FAD 0.000006421 0.49827 5.88235
166 2IID PHE 0.00000009229 0.49569 6.10687
167 2IID FAD 0.00000009229 0.49569 6.10687
168 2WPF WPF 0.00001176 0.47036 6.10687
169 2WPF FAD 0.00001545 0.46481 6.10687
170 3NKS FAD 0.0000000882 0.45675 6.10687
171 3CGD FAD 0.0001006 0.43155 6.10687
172 3CGD COA 0.0001006 0.43155 6.10687
173 3CGD NAD 0.0001006 0.43155 6.10687
174 4D04 FAD 0.0001414 0.41749 6.10687
175 4D04 NAP 0.0001414 0.41749 6.10687
176 2OOR NAD 0.002833 0.45107 6.32184
177 2OOR TXP 0.0188 0.401 6.32184
178 5JCA NDP 0.000002273 0.46807 6.33803
179 5JCA FAD 0.0000002019 0.45747 6.33803
180 1GET FAD 0.0000003639 0.49505 6.36132
181 1GET NAP 0.0000004442 0.49451 6.36132
182 2F5Z FAD 0.00000005356 0.47682 6.36132
183 1ZMD FAD 0.00000005509 0.4767 6.36132
184 2HQM FAD 0.00000006705 0.47222 6.36132
185 1HYH NAD 0.002277 0.43243 6.47249
186 2NU5 NAG 0.02223 0.44319 6.55738
187 2GUC MAN 0.03062 0.43589 6.55738
188 2NUO BGC 0.04573 0.42375 6.55738
189 3QJ4 FAD 0.000000004756 0.62668 6.61578
190 5U8U FAD 0.000001846 0.47362 6.61578
191 1MUU NAD 0.00101 0.46162 6.61578
192 1BZL FAD 0.00003341 0.4551 6.61578
193 3IHG FAD 0.0000008661 0.40561 6.61578
194 4CNK FAD 0.00000203 0.42285 6.64962
195 3TLJ SAH 0.006173 0.43242 6.70241
196 2UYQ SAM 0.004102 0.48445 6.77419
197 3V1Y NAD 0.0007701 0.46357 6.82493
198 2YG3 FAD 0.00000002789 0.58951 6.87023
199 5WGR FAD 0.00002551 0.48285 6.87023
200 2XVF FAD 0.00001002 0.40354 6.87023
201 3SQP FAD 0.00001361 0.4918 7.12468
202 3LAD FAD 0.0000001441 0.4645 7.12468
203 1QO8 FAD 0.0000009482 0.44359 7.12468
204 3QFA FAD 0.00000234 0.43408 7.12468
205 3UOY FAD 0.00007052 0.42946 7.12468
206 3UOY NAP 0.00007052 0.42946 7.12468
207 1T9D P22 0.03771 0.42896 7.12468
208 3ICR FAD 0.000002348 0.4209 7.12468
209 3ICS FAD 0.000003179 0.42042 7.12468
210 3ICT FAD 0.000002814 0.41858 7.12468
211 3SJU NDP 0.01022 0.40574 7.16846
212 3A4T SFG 0.000999 0.47208 7.29927
213 5TTJ FAD 0.0000000212 0.47401 7.34694
214 1RSG FAD 0.00000003019 0.48131 7.37913
215 2X3N FAD 0.00005826 0.47836 7.37913
216 2RAB NAD 0.000001381 0.47824 7.37913
217 2RAB FAD 0.0000001969 0.46626 7.37913
218 5JJR SAH 0.002545 0.46381 7.37913
219 1LVL FAD 0.001149 0.40769 7.37913
220 2Q0L FAD 0.000001548 0.52328 7.3955
221 2Q0L NAP 0.0007703 0.49816 7.3955
222 1Y8Q ATP 0.00009111 0.51175 7.51445
223 2GMH FAD 0.00000125 0.52659 7.63359
224 2VDV SAM 0.0006631 0.50637 7.63359
225 1MAI I3P 0.01194 0.4585 7.63359
226 2XVE FAD 0.00008535 0.42145 7.63359
227 4C3Y FAD 0.000009852 0.41483 7.63359
228 4C3Y ANB 0.0000339 0.4122 7.63359
229 3DXY SAM 0.001275 0.49647 7.79817
230 5J60 FAD 0.000001559 0.43132 7.8125
231 1V59 FAD 0.0000000576 0.48157 7.88804
232 2BRY FAD 0.000002169 0.40457 7.88804
233 2Q46 NAP 0.01094 0.41843 7.90514
234 3BKR PLM 0.04736 0.40954 7.93651
235 2CVQ NDP 0.003648 0.42898 7.95107
236 2GAG NAD 0.0000000443 0.45824 8.08081
237 2GAG FAD 0.00003597 0.41109 8.08081
238 2GAG FOA 0.00003688 0.41106 8.08081
239 3NYC IAR 0.0000167 0.46299 8.13648
240 3NYC FAD 0.0000167 0.46299 8.13648
241 5MBX FAD 0.00000006327 0.50049 8.14249
242 5MBX SP5 0.00000006327 0.50049 8.14249
243 3OZ2 FAD 0.000001155 0.53126 8.31234
244 1COY FAD 0.000007158 0.41755 8.39695
245 1COY AND 0.00008367 0.41654 8.39695
246 2CDU FAD 0.000004169 0.40956 8.40708
247 1PS9 FAD 0.00000008811 0.46465 8.6514
248 3G5S FAD 0.0000144 0.40002 8.6514
249 3OFK SAH 0.0009363 0.47339 8.7963
250 5I39 FAD 0.000004781 0.41382 8.90585
251 1VL8 NAP 0.005665 0.41186 8.98876
252 2CUL FAD 0.000006039 0.40341 9.05172
253 2V3B FAD 0.000005235 0.41091 9.09091
254 1F8G NAD 0.003753 0.4454 9.11458
255 3GDH SAH 0.00171 0.45464 9.12863
256 1H82 FAD 0.00000008126 0.49956 9.16031
257 1H82 GZZ 0.0000001914 0.49887 9.16031
258 3LU1 NAD 0.003604 0.4267 9.34066
259 4IV9 FAD 0.0000000247 0.47835 9.41476
260 4AP3 NAP 0.00007693 0.42607 9.41476
261 4AP3 FAD 0.00007693 0.42607 9.41476
262 3CTY FAD 0.00000001927 0.49144 9.66921
263 5EZ7 FAD 0.000009331 0.4112 9.94898
264 2Q7V FAD 0.00000004869 0.47244 10.1538
265 2ZXI FAD 0.00001828 0.49724 10.1781
266 4R6W SAH 0.01326 0.40111 10.1781
267 5FJN BE2 0.000008787 0.42459 10.307
268 5FJN FAD 0.000006268 0.42116 10.307
269 1E3W NAD 0.002044 0.43692 10.728
270 1E6W NAD 0.00353 0.42708 10.7692
271 5DXA SFG 0.004776 0.43752 10.8883
272 3OU2 SAH 0.002322 0.44567 11.0092
273 4ZCC FAD 0.000000008462 0.51743 11.0119
274 4ZCC NAI 0.000000008462 0.51743 11.0119
275 4QTU SAM 0.00348 0.45358 11.5385
276 1NAA 6FA 0.0000041 0.50204 11.7048
277 1NAA ABL 0.00001456 0.46016 11.7048
278 5J7X FAD 0.000009224 0.40828 11.7048
279 3RNM FAD 0.00000004943 0.47748 12.069
280 2EG5 SAH 0.001343 0.49044 12.6344
281 3AYI HCI 0.000001507 0.4606 12.9771
282 3AYI FAD 0.00000137 0.45965 12.9771
283 4GUS FAD 0.00000001799 0.57972 15.0127
284 4GUT FAD 0.00000002775 0.49215 15.0127
285 4FWE FAD 0.0000000198 0.48787 15.0127
286 4HSU FAD 0.00000003681 0.48328 15.0127
287 2VVL FAD 0.00000003148 0.58342 15.5216
288 2VVM FAD 0.00000002709 0.47519 15.5216
289 4MOP 2H5 0.000005457 0.47589 15.6398
290 1JNR FAD 0.000008441 0.46132 16
291 4JDR FAD 0.0000003446 0.45058 16.7939
292 5ODQ FAD 0.0000006283 0.44684 18.0602
293 4J56 FAD 0.000000438 0.45647 18.4211
294 4X9M FAD 0.000008063 0.41604 19.5929
295 3AD8 NAD 0.00000002786 0.45269 29.2929
296 3AD8 FAD 0.0003741 0.40763 29.2929
297 3AD8 PYC 0.0003741 0.40763 29.2929
Pocket No.: 2; Query (leader) PDB : 5BR7; Ligand: FLC; Similar sites found: 279
This union binding pocket(no: 2) in the query (biounit: 5br7.bio2) has 60 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4BV6 FAD 0.0000157 0.40891 1.27226
2 4ONQ SFG 0.03725 0.40637 1.40056
3 2FR1 NDP 0.002598 0.42766 1.52672
4 1P31 EPU 0.03761 0.40617 1.52672
5 1F3L SAH 0.006716 0.43365 1.55763
6 3U31 NAD 0.01903 0.41255 1.72414
7 1N4W FAD 0.00001997 0.40998 1.78117
8 1CER NAD 0.002117 0.4445 1.81269
9 1GZ6 NAI 0.01285 0.40167 1.88088
10 3NT6 FAD 0.00001505 0.40268 1.91638
11 2PV7 NAD 0.004697 0.42686 2.01342
12 5EVY FAD 0.0007694 0.4737 2.03562
13 1XDS SAM 0.01031 0.44435 2.13904
14 1QZZ SAM 0.01382 0.43771 2.13904
15 1PN0 IPH 0.00001418 0.42578 2.29008
16 1PN0 FAD 0.00001246 0.42503 2.29008
17 3GFB NAD 0.00805 0.41684 2.29008
18 2FKA BEF 0.005953 0.46044 2.32558
19 5ENZ UDP 0.02628 0.41681 2.33766
20 5FTW SAH 0.02213 0.41207 2.34375
21 3F8D FAD 0.00001845 0.4489 2.47678
22 3WMX NAD 0.007159 0.4215 2.51397
23 2GV8 FAD 0.000006005 0.52605 2.54453
24 4EMI NAD 0.00006237 0.42533 2.54453
25 2GV8 NDP 0.0122 0.41629 2.54453
26 4EMI FAD 0.000006441 0.41255 2.54453
27 5JCM NAD 0.0002604 0.41143 2.66075
28 5JCM FAD 0.0002537 0.41099 2.66075
29 5JCM ISD 0.0002737 0.41081 2.66075
30 3MQ2 SAH 0.04422 0.40533 2.75229
31 2CVZ NDP 0.01244 0.41104 2.76817
32 4DPL NAP 0.009344 0.40951 2.78552
33 5VN0 FAD 0.00002357 0.49002 2.79898
34 5VN0 NAI 0.0002005 0.41573 2.79898
35 1NPD NAD 0.01551 0.41159 2.79898
36 3LXD FAD 0.000008494 0.40311 2.79898
37 2JAP NDP 0.01225 0.40252 2.83401
38 1VQW FAD 0.000003876 0.40087 2.84464
39 2V3A FAD 0.000005611 0.41172 2.86458
40 5E8J SAH 0.001988 0.48158 2.88462
41 4O0L NDP 0.009238 0.40755 2.90909
42 1E3I CXF 0.007249 0.40165 2.92553
43 3ITJ FAD 0.00002842 0.41984 2.95858
44 5N53 8NB 0.03654 0.43168 3.07692
45 4OBW SAM 0.005089 0.44905 3.11284
46 5HJM MTA 0.003427 0.45391 3.125
47 1GEG NAD 0.002513 0.4332 3.125
48 3EGV SAH 0.01011 0.4377 3.14961
49 2BKX F6R 0.01792 0.43181 3.30579
50 4DMG SAM 0.005442 0.46299 3.30789
51 5MQ6 NDP 0.00479 0.43746 3.30789
52 4MIG G3F 0.000021 0.42017 3.30789
53 3GDN HBX 0.00003482 0.41933 3.30789
54 3GDN FAD 0.00002791 0.40665 3.30789
55 2DT5 NAD 0.002884 0.43328 3.31754
56 3ZNN 4WL 0.00009616 0.41552 3.45821
57 3ZNN FAD 0.00009616 0.41552 3.45821
58 3WGT FAD 0.00003691 0.41419 3.45821
59 3WGT QSC 0.00005341 0.41149 3.45821
60 4UP3 FAD 0.000002281 0.4272 3.50318
61 1FL2 FAD 0.000001445 0.43 3.54839
62 1Q1R FAD 0.000005813 0.51589 3.56234
63 4G74 FAD 0.00003322 0.49059 3.56234
64 4G74 UQ5 0.0001741 0.43678 3.56234
65 2Q1W NAD 0.0009339 0.44293 3.6036
66 1YXM ADE 0.002652 0.49417 3.63036
67 1P77 ATR 0.003433 0.48851 3.67647
68 1NYT NAP 0.02335 0.40126 3.69004
69 1D1T NAD 0.007863 0.40827 3.75335
70 2IVD FAD 0.0000001084 0.58509 3.81679
71 4FFG LBS 0.01544 0.4336 3.81679
72 5HSA FAS 0.00002383 0.40568 3.81679
73 4ZRN NAD 0.001058 0.43827 3.84615
74 2R4J FAD 0.00006191 0.41394 3.99202
75 2R4J 13P 0.00006191 0.41394 3.99202
76 4YCA NDP 0.001782 0.44775 4.08163
77 4K28 NAD 0.002955 0.44105 4.08922
78 3GD4 NAD 0.00005174 0.438 4.10959
79 3GD4 FAD 0.00009166 0.41729 4.10959
80 1D4D FAD 0.0000007002 0.44768 4.1958
81 5TUF FAD 0.000007157 0.53063 4.3257
82 5TUF TDC 0.00009272 0.42555 4.3257
83 2B9W FAD 0.0000001071 0.49725 4.48113
84 4Z24 FAD 0.00001848 0.40988 4.58015
85 3QVP FAD 0.00002486 0.40872 4.58015
86 2I7C AAT 0.007873 0.40415 4.58015
87 4REP FAD 0.00000005261 0.46481 4.64646
88 4EMJ FAD 0.00001772 0.40452 4.6729
89 1Q9I FAD 0.000007253 0.44656 4.72855
90 1Q9I TEO 0.000007253 0.44656 4.72855
91 4CS9 AMP 0.01366 0.45739 4.7619
92 3FG2 FAD 0.00002357 0.50628 4.83461
93 4YRY NAD 0.00000144 0.46008 4.83461
94 5BVA FAD 0.00000108 0.44596 4.83461
95 4YRY FAD 0.0000008103 0.44201 4.83461
96 3UCL NAP 0.0003353 0.41047 4.83461
97 3UCL CYH 0.0003148 0.40905 4.83461
98 3UCL FAD 0.0003148 0.40905 4.83461
99 4HA6 FAD 0.00004703 0.4019 4.83461
100 5EB4 FAD 0.00003004 0.40147 4.83461
101 3EGI ADP 0.0009367 0.52058 4.85437
102 5H81 NAP 0.005493 0.43771 4.88432
103 1XHC FAD 0.00000075 0.42677 4.90463
104 1H5Q NAP 0.006214 0.41461 4.90566
105 5JE8 NAD 0.005869 0.42788 4.96689
106 3A28 NAD 0.009209 0.40978 5.03876
107 3LRE ADP 0.03358 0.42694 5.07042
108 4NTC FAD 0.0000013 0.43695 5.07463
109 1MO9 FAD 0.00000329 0.47669 5.08906
110 1MO9 KPC 0.000004969 0.47211 5.08906
111 4OPC PGT 0.00001706 0.46891 5.08906
112 4OPC FDA 0.00001288 0.46851 5.08906
113 5MZI FAD 0.0000315 0.43228 5.08906
114 5MZI FYK 0.00003639 0.43207 5.08906
115 2E5V FAD 0.000008645 0.41982 5.08906
116 1GPE FAD 0.00002692 0.41232 5.08906
117 3NTD FAD 0.000006117 0.41167 5.08906
118 4RDH AMP 0.0007973 0.4974 5.20833
119 3AB1 FAD 0.000002219 0.42661 5.27778
120 1VE3 SAM 0.008518 0.43806 5.28634
121 1W73 NAP 0.00355 0.44041 5.29801
122 1N2X SAM 0.01445 0.4155 5.31561
123 2A8X FAD 0.000001871 0.51385 5.34351
124 2Z3Y F2N 0.00000002947 0.48416 5.34351
125 1E1M NAP 0.000001217 0.46222 5.34351
126 1E1M FAD 0.000001217 0.46222 5.34351
127 1E6E FAD 0.0000001752 0.44186 5.34351
128 3NTA FAD 0.000007201 0.41114 5.34351
129 4YNU LGC 0.00005617 0.40991 5.34351
130 1YKJ PHB 0.0002843 0.40878 5.34351
131 1YKJ FAD 0.0002843 0.40878 5.34351
132 2Y6Q I7T 0.00005594 0.40708 5.34351
133 4YNU FAD 0.00003885 0.40636 5.34351
134 4TM3 FAD 0.0006219 0.40264 5.34351
135 3VYW SAM 0.005867 0.43945 5.51948
136 5TS5 FAD 0.00000005472 0.57488 5.59796
137 2NPX FAD 0.00000269 0.52843 5.59796
138 3CGB FAD 0.000008272 0.51014 5.59796
139 2NPX NAD 0.00001786 0.44862 5.59796
140 2JB2 PHE 0.0000005521 0.44538 5.59796
141 2JB2 FAD 0.0000004696 0.44446 5.59796
142 1GTE FAD 0.00002866 0.4385 5.59796
143 1KNR FAD 0.000005581 0.41965 5.59796
144 4TXI FAD 0.00000161 0.40575 5.59796
145 1ZBQ NAD 0.009839 0.40434 5.59796
146 1YY5 FAD 0.00000018 0.46625 5.65302
147 4YSX FAD 0.000004052 0.42342 5.76923
148 4M52 FAD 0.0000006895 0.44522 5.85242
149 3E1T FAD 0.000001097 0.44443 5.85242
150 5G3U FDA 0.000001253 0.42942 5.85242
151 1FEC FAD 0.00001013 0.42617 5.85242
152 5G3U ITW 0.000007706 0.4252 5.85242
153 5BUK FAD 0.0000116 0.42009 5.85242
154 4JNA FAD 0.000006819 0.49735 5.88235
155 2IID PHE 0.0000002831 0.48194 6.10687
156 2IID FAD 0.0000002831 0.48194 6.10687
157 2WPF WPF 0.00004658 0.45183 6.10687
158 2WPF FAD 0.00005849 0.447 6.10687
159 3NKS FAD 0.000000746 0.43358 6.10687
160 3CGD FAD 0.0001733 0.42449 6.10687
161 3CGD COA 0.0001733 0.42449 6.10687
162 3CGD NAD 0.0001733 0.42449 6.10687
163 4D04 NAP 0.0004627 0.40269 6.10687
164 4D04 FAD 0.0004627 0.40269 6.10687
165 2OOR NAD 0.002833 0.45107 6.32184
166 5JCA NDP 0.000002361 0.4676 6.33803
167 5JCA FAD 0.0000005992 0.4453 6.33803
168 1GET NAP 0.000002231 0.47405 6.36132
169 1GET FAD 0.000002011 0.4735 6.36132
170 2F5Z FAD 0.0000002734 0.45847 6.36132
171 1ZMD FAD 0.0000002949 0.45774 6.36132
172 2HQM FAD 0.0000003715 0.45241 6.36132
173 1HYH NAD 0.002247 0.43267 6.47249
174 3QJ4 FAD 0.00000002812 0.59813 6.61578
175 5U8U FAD 0.00000307 0.46723 6.61578
176 1MUU NAD 0.001026 0.46132 6.61578
177 1BZL FAD 0.00008787 0.44214 6.61578
178 3IHG FAD 0.0000009749 0.40359 6.61578
179 4CNK FAD 0.00000203 0.42285 6.64962
180 3TLJ SAH 0.007333 0.42901 6.70241
181 2UYQ SAM 0.004102 0.48445 6.77419
182 3V1Y NAD 0.0007362 0.46442 6.82493
183 2YG3 FAD 0.0000001514 0.56305 6.87023
184 5WGR FAD 0.00002724 0.48183 6.87023
185 3SQP FAD 0.00004458 0.47458 7.12468
186 3LAD FAD 0.000000772 0.4455 7.12468
187 1QO8 FAD 0.000002935 0.43037 7.12468
188 1T9D P22 0.03771 0.42896 7.12468
189 3QFA FAD 0.000003999 0.42796 7.12468
190 3ICT FAD 0.00000275 0.41883 7.12468
191 3ICR FAD 0.000002856 0.41838 7.12468
192 3ICS FAD 0.000003833 0.41793 7.12468
193 3UOY NAP 0.0002591 0.41301 7.12468
194 3UOY FAD 0.0002591 0.41301 7.12468
195 3SJU NDP 0.01107 0.40433 7.16846
196 3A4T SFG 0.001987 0.45822 7.29927
197 5TTJ FAD 0.0000001147 0.45632 7.34694
198 2X3N FAD 0.00006209 0.47733 7.37913
199 2RAB NAD 0.000005588 0.46062 7.37913
200 1RSG FAD 0.0000001989 0.45995 7.37913
201 5JJR SAH 0.005507 0.44736 7.37913
202 2RAB FAD 0.000001015 0.44722 7.37913
203 2Q0L FAD 0.000002428 0.51633 7.3955
204 2Q0L NAP 0.0007819 0.49783 7.3955
205 1Y8Q ATP 0.0001273 0.50523 7.51445
206 2GMH FAD 0.000001238 0.52673 7.63359
207 2VDV SAM 0.0006631 0.50637 7.63359
208 1MAI I3P 0.01194 0.4585 7.63359
209 4C3Y ANB 0.00004441 0.40842 7.63359
210 2XVE FAD 0.0003158 0.40526 7.63359
211 4C3Y FAD 0.00002919 0.40236 7.63359
212 3DXY SAM 0.001275 0.49647 7.79817
213 5J60 FAD 0.000002289 0.42649 7.8125
214 1V59 FAD 0.0000002896 0.46266 7.88804
215 2BRY FAD 0.000002125 0.40491 7.88804
216 2Q46 NAP 0.01094 0.41843 7.90514
217 2CVQ NDP 0.003624 0.4291 7.95107
218 2GAG NAD 0.0000004381 0.43452 8.08081
219 2GAG FOA 0.00004415 0.40835 8.08081
220 2GAG FAD 0.00005859 0.40512 8.08081
221 3NYC IAR 0.00002268 0.45876 8.13648
222 3NYC FAD 0.00002268 0.45876 8.13648
223 5MBX SP5 0.0000003962 0.47855 8.14249
224 5MBX FAD 0.0000003962 0.47855 8.14249
225 2YVK MRU 0.03389 0.41121 8.28877
226 3OZ2 FAD 0.000001065 0.53253 8.31234
227 1COY AND 0.0001115 0.41357 8.39695
228 1COY FAD 0.0000208 0.40574 8.39695
229 2CDU FAD 0.000004169 0.40956 8.40708
230 1PS9 FAD 0.0000007379 0.44131 8.6514
231 3G5S FAD 0.00001434 0.40007 8.6514
232 3OFK SAH 0.001004 0.47199 8.7963
233 5I39 FAD 0.000006122 0.41066 8.90585
234 1VL8 NAP 0.0057 0.41175 8.98876
235 2CUL FAD 0.000006782 0.40187 9.05172
236 2V3B FAD 0.000005418 0.41008 9.09091
237 1F8G NAD 0.003753 0.4454 9.11458
238 3GDH SAH 0.002284 0.44901 9.12863
239 1H82 GZZ 0.000001002 0.47826 9.16031
240 1H82 FAD 0.0000005048 0.47744 9.16031
241 3LU1 NAD 0.003604 0.4267 9.34066
242 4IV9 FAD 0.0000002334 0.45388 9.41476
243 4AP3 FAD 0.0003379 0.40745 9.41476
244 4AP3 NAP 0.0003379 0.40745 9.41476
245 3CTY FAD 0.00000007603 0.47534 9.66921
246 2AL2 PEP 0.02829 0.42475 9.66921
247 5EZ7 FAD 0.00002375 0.40049 9.94898
248 2Q7V FAD 0.0000003326 0.4501 10.1538
249 2ZXI FAD 0.00002022 0.49559 10.1781
250 5FJN BE2 0.00001208 0.42052 10.307
251 5FJN FAD 0.000008092 0.418 10.307
252 1E3W NAD 0.002044 0.43692 10.728
253 1E6W NAD 0.00353 0.42708 10.7692
254 5DXA SFG 0.006074 0.43274 10.8883
255 3OU2 SAH 0.005211 0.43016 11.0092
256 4ZCC FAD 0.00000004606 0.49767 11.0119
257 4ZCC NAI 0.00000004606 0.49767 11.0119
258 4QTU SAM 0.00348 0.45358 11.5385
259 1NAA 6FA 0.00002502 0.47483 11.7048
260 1NAA ABL 0.00005104 0.44325 11.7048
261 3RNM FAD 0.0000002577 0.45837 12.069
262 2EG5 SAH 0.001624 0.48615 12.6344
263 3AYI HCI 0.000006661 0.4427 12.9771
264 3AYI FAD 0.000006171 0.44174 12.9771
265 4GUS FAD 0.0000001325 0.55005 15.0127
266 4GUT FAD 0.000000188 0.4701 15.0127
267 4FWE FAD 0.0000001449 0.46555 15.0127
268 4HSU FAD 0.0000002718 0.46042 15.0127
269 2VVL FAD 0.0000001463 0.5597 15.5216
270 2VVM FAD 0.0000001394 0.45695 15.5216
271 4MOP 2H5 0.00001883 0.45899 15.6398
272 1JNR FAD 0.00001685 0.45243 16
273 4JDR FAD 0.0000005162 0.44557 16.7939
274 5ODQ FAD 0.000001256 0.43949 18.0602
275 4J56 FAD 0.000002027 0.43856 18.4211
276 4X9M FAD 0.000009337 0.41419 19.5929
277 3AD8 NAD 0.0000002838 0.42991 29.2929
278 3AD8 FAD 0.0004907 0.40421 29.2929
279 3AD8 PYC 0.0004907 0.40421 29.2929
Pocket No.: 3; Query (leader) PDB : 5BR7; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5br7.bio1) has 60 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5BR7; Ligand: FLC; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5br7.bio1) has 60 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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