Receptor
PDB id Resolution Class Description Source Keywords
4ZSJ 2.48 Å EC: 2.7.11.24 MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR HOMO SAPIENS KINASE INHIBITOR TRANSFERASE
Ref.: DISCOVERY OF A NOVEL ALLOSTERIC INHIBITOR-BINDING S ERK5: COMPARISON WITH THE CANONICAL KINASE HINGE AT SITE. ACTA CRYSTALLOGR D STRUCT V. 72 682 2016 BIOL
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
4R0 A:405;
Valid;
none;
ic50 = 2.3 uM
308.767 C13 H17 Cl N6 O Cc1cc...
GOL A:401;
A:403;
A:404;
A:402;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5BYZ 1.65 Å EC: 2.7.11.24 ERK5 IN COMPLEX WITH SMALL MOLECULE HOMO SAPIENS ERK5 KINASE INHIBITOR TRANSFERASE
Ref.: DISCOVERY OF A NOVEL ALLOSTERIC INHIBITOR-BINDING S ERK5: COMPARISON WITH THE CANONICAL KINASE HINGE AT SITE. ACTA CRYSTALLOGR D STRUCT V. 72 682 2016 BIOL
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 4ZSL - 4QZ C17 H17 Cl N6 O C[C@@H](c1....
2 5BYZ ic50 = 0.042 uM 4WE C25 H32 F N7 O Cc1ncc(n1C....
3 4ZSJ ic50 = 2.3 uM 4R0 C13 H17 Cl N6 O Cc1cc(ccc1....
4 4ZSG - 4QX C12 H15 Cl N6 O CC(C)NC(=O....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 4ZSL - 4QZ C17 H17 Cl N6 O C[C@@H](c1....
2 5BYZ ic50 = 0.042 uM 4WE C25 H32 F N7 O Cc1ncc(n1C....
3 4ZSJ ic50 = 2.3 uM 4R0 C13 H17 Cl N6 O Cc1cc(ccc1....
4 4ZSG - 4QX C12 H15 Cl N6 O CC(C)NC(=O....
50% Homology Family (257)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 3GCV Kd = 74 nM SS6 C29 H30 N8 O Cc1cccc(c1....
2 3L8S Kd = 99 nM BFF C20 H24 Br F2 N5 O3 S c1c(cc(c(c....
3 3RIN ic50 = 1.3 nM I2O C23 H24 N2 O2 Cc1ccc(cc1....
4 5N65 - 8OT C20 H18 N4 S c1ccc(cc1)....
5 4FA2 - SB0 C20 H21 F N4 O2 COc1nccc(n....
6 2GHM - LIC C24 H28 Cl N5 O3 C[C@@H](C(....
7 1W84 ic50 = 35 uM L12 C15 H14 N2 c1ccc2c(c1....
8 4EH5 - IRG C17 H16 N4 c1ccc(cc1)....
9 2BAK Kd = 37 nM AQZ C32 H37 N7 O4 Cc1ccc(cc1....
10 3HV6 ic50 = 5500 nM R39 C27 H35 N5 O3 Cc1ccc(cc1....
11 3HP2 - P36 C19 H16 Br N O2 c1ccc(cc1)....
12 1WBO ic50 = 1 mM 2CH C6 H5 Cl O c1ccc(c(c1....
13 4KIQ ic50 = 23 nM 1RA C23 H23 N3 O4 CCOC(=O)n1....
14 3GC7 ic50 = 0.4 nM B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
15 4EH6 - IRG C17 H16 N4 c1ccc(cc1)....
16 5MTX Kd = 17.7 nM FJI C34 H31 F N4 O5 c1ccc(cc1)....
17 2ZB0 Ki = 0.24 uM GK3 C24 H18 N4 O2 Cc1ccc(cc1....
18 2GTM ic50 = 542 nM LID C19 H15 Cl F2 N6 CCn1c2c(cn....
19 5N66 - B96 C31 H37 N5 O3 Cc1ccc(cc1....
20 2YIX Kd = 3.3 nM YIX C19 H23 N5 O S CCNC(=O)NC....
21 3OCG ic50 = 3 nM OCG C21 H18 N6 O3 Cc1ccc(cc1....
22 1BL7 - SB4 C18 H19 F N6 c1cc(ccc1c....
23 3P7C ic50 = 0.022 uM P7C C25 H33 Cl2 N5 O3 S CC(C)(C)c1....
24 5TBE Kd = 4.4 nM 78L C33 H30 F2 N4 O4 S c1cc(sc1)C....
25 4KIP ic50 = 7 nM 1R9 C21 H18 Cl N3 O2 S Cc1ccc(cc1....
26 2EWA - SB2 C21 H16 F N3 O S C[S@](=O)c....
27 2GHL - LIB C23 H26 Cl N5 O3 C[C@@H](C(....
28 1ZZ2 ic50 = 6 uM B11 C24 H26 F N3 O4 S c1ccc(c(c1....
29 3ZSI - 52P C19 H9 Cl2 F2 N3 O S c1cc(c(c(c....
30 2YIW - YIW C30 H33 N7 O S CC(C)c1nnc....
31 1A9U - SB2 C21 H16 F N3 O S C[S@](=O)c....
32 1M7Q ic50 = 2.6 nM DQO C24 H20 Cl2 F2 N4 O c1cc(c(c(c....
33 5MTY Kd = 1.3 nM HB9 C29 H23 F2 N3 O4 S c1cc(sc1)C....
34 4EH7 - IRG C17 H16 N4 c1ccc(cc1)....
35 1YQJ ic50 = 7.3 nM 6NP C30 H27 N5 c1ccc(cc1)....
36 4EH3 - NAR C15 H12 O5 c1cc(ccc1[....
37 4AA5 ic50 = 6.7 nM NQB C24 H27 N5 O2 Cc1ccc(cc1....
38 1OVE ic50 = 0.74 nM 358 C26 H22 Cl2 F2 N2 O c1cc(c(c(c....
39 3UVP ic50 = 0.035 uM 048 C24 H21 F N2 O2 c1ccc(cc1)....
40 5N67 - 8ON C28 H30 N6 O CC(=O)N1CC....
41 3NNV ic50 = 27 nM 437 C25 H26 N4 O2 CC(C)(C)c1....
42 3CTQ ic50 = 40 nM 337 C30 H34 N6 O5 S Cc1ccc(cc1....
43 3IW7 - IPK C26 H26 N4 O S c1ccc(cc1)....
44 3ITZ ic50 = 1.4 nM P66 C21 H15 Cl F2 N6 O c1cc(c(c(c....
45 2ZB1 Ki = 0.48 uM GK4 C21 H21 N3 O2 Cc1ccc(cc1....
46 3HV5 ic50 = 150 nM R24 C30 H29 N7 O3 Cc1ccc(cc1....
47 1WBW ic50 = 44 uM LI4 C16 H14 N2 O c1ccc2c(c1....
48 3P79 ic50 = 2.3 uM P79 C24 H29 N5 O4 S CC(C)(C)c1....
49 3HV7 ic50 = 90 nM 1AU C24 H25 N5 O CC(C)(C)c1....
50 3GFE ic50 = 3.2 nM P37 C24 H21 F2 N5 O2 Cc1ccc(cc1....
51 3ZYA - 2A8 C21 H18 N2 O c1ccc2c(c1....
52 2RG5 ic50 = 3.1 nM 279 C19 H22 N6 O3 CCNC(=O)c1....
53 3L8X ic50 = 10 nM N4D C20 H18 N6 O Cc1ccc(cc1....
54 3GCS Kd = 56 nM BAX C21 H16 Cl F3 N4 O3 CNC(=O)c1c....
55 3ZS5 - SB2 C21 H16 F N3 O S C[S@](=O)c....
56 3D83 Ki = 4.4 nM GK6 C28 H30 N4 O3 Cc1ccc(cc1....
57 1YW2 ic50 = 141 nM PGJ C22 H18 F N3 O5 CCOC[N@]1C....
58 1W82 ic50 = 196 nM L10 C20 H21 Cl N4 O CC(C)(C)C1....
59 3ZSG - T75 C24 H21 N3 O S CCc1nc(c(s....
60 5TCO Kd = 3.14 nM 79Q C35 H33 F N4 O4 c1ccc(cc1)....
61 4EH8 - IRG C17 H16 N4 c1ccc(cc1)....
62 3GCP Kd = 15 nM SB2 C21 H16 F N3 O S C[S@](=O)c....
63 3HLL Ki = 0.0058 uM I45 C22 H19 Br F2 N2 O3 Cc1ccc(cc1....
64 1ZZL ic50 = 5 nM TZY C18 H15 F N4 O CC(C)c1nnc....
65 2RG6 ic50 = 2.2 nM 287 C25 H26 N6 O3 Cc1ccc(cc1....
66 3MPT ic50 = 0.25 uM 1GK C18 H16 N2 O3 Cc1ccccc1C....
67 1BL6 - SB6 C18 H16 F N3 c1cc(ccc1c....
68 3NNW ic50 = 9 nM EDD C22 H23 Cl2 N5 O2 CC(C)(C)C1....
69 3GI3 Kd < 1.8 nM B10 C33 H39 N5 O5 S CC(C)(C)c1....
70 3K3J - I46 C14 H9 F2 N3 c1cc(ccc1c....
71 3HEC ic50 = 70 uM STI C29 H31 N7 O Cc1ccc(cc1....
72 1IAN - D13 C21 H16 I N3 O S C[S@@](=O)....
73 3FC1 - 52P C19 H9 Cl2 F2 N3 O S c1cc(c(c(c....
74 3MVM ic50 = 13 nM 39P C22 H23 N7 O3 CCCNC(=O)c....
75 3NNU ic50 = 48 nM EDB C22 H17 Cl2 N5 O2 S c1cc(cc(c1....
76 1W7H ic50 = 1 mM 3IP C12 H12 N2 O c1ccc(cc1)....
77 3U8W ic50 = 1 nM 09J C24 H21 Cl F N5 O2 CCN1C(=O)C....
78 1WBS ic50 = 0.63 uM LI2 C26 H25 F N4 O2 c1cc2c(cc1....
79 4E6C Kd ~ 15 uM 0O8 C25 H53 N O4 P CCCCCCCCCC....
80 5N68 - 8OK C26 H27 N5 O c1ccc(cc1)....
81 1WBV ic50 = 162 uM LI3 C19 H18 F N3 O2 c1cc2c(cc[....
82 4EH2 - IRG C17 H16 N4 c1ccc(cc1)....
83 3HA8 - 5JZ C36 H38 N8 O5 CCOc1nc(nc....
84 3HEG ic50 = 0.057 uM BAX C21 H16 Cl F3 N4 O3 CNC(=O)c1c....
85 2ZAZ Ki = 0.4 uM GK1 C20 H15 N3 O2 S Cc1ccc(cc1....
86 3HP5 - I46 C14 H9 F2 N3 c1cc(ccc1c....
87 5ML5 ic50 = 10 nM 1VI C26 H25 F N4 O3 S COc1ccc(c(....
88 4DLI Kd = 2.4 uM IRG C17 H16 N4 c1ccc(cc1)....
89 3P78 ic50 = 0.11 uM P78 C24 H27 N3 O4 S2 CC(C)(C)c1....
90 4EH9 - IRG C17 H16 N4 c1ccc(cc1)....
91 1YWR ic50 = 32 nM LI9 C27 H29 F N6 O C[C@@H](c1....
92 3IW5 Kd = 0.839 uM DF3 C28 H24 F3 N3 O4 S c1ccc2c(c1....
93 3HV3 ic50 = 900 nM R49 C30 H31 N7 O Cc1cccc(c1....
94 4A9Y - RNY C32 H37 N7 O4 Cc1ccc(cc1....
95 3GCU - R48 C29 H30 N8 O Cc1ccc(cc1....
96 1OUY ic50 = 4.3 nM 094 C24 H18 Cl2 F2 N4 O S c1cc(c(c(c....
97 3D7Z Ki = 12 nM GK5 C22 H24 N2 O2 Cc1ccc(cc1....
98 2YIS - YIS C35 H34 Cl N7 O3 S2 CC(C)(C)c1....
99 1OUK ic50 = 0.13 nM 084 C28 H29 F3 N6 C[C@@H](c1....
100 3BV2 Ki = 0.44 nM P38 C33 H32 N8 O3 Cc1ccc(cc1....
101 4R3C - GG5 C14 H10 F N3 c1cc(ccc1c....
102 4L8M ic50 = 0.001 uM F46 C33 H30 F N3 O5 c1ccc(cc1)....
103 4E6A - 0O9 C32 H65 O10 P CCCCCCCCCC....
104 1WBN ic50 = 0.35 uM L09 C20 H22 Cl N5 O2 CC(C)(C)c1....
105 2QD9 ic50 = 13 nM LGF C27 H24 F2 N6 O5 COC1=NC2=N....
106 3HUC Kd = 1030 nM G97 C20 H16 N6 O C=CC(=O)Nc....
107 3HL7 Ki = 0.023 uM I47 C20 H20 Cl N5 O2 c1cc(ccc1c....
108 4EHV - IRG C17 H16 N4 c1ccc(cc1)....
109 2GTN ic50 = 4 nM LIE C20 H16 F3 N5 O CC(C)n1c2c....
110 3HRB ic50 = 21 nM I39 C19 H14 F2 N2 O2 Cc1ccccc1c....
111 3BX5 ic50 = 1.5 nM 304 C17 H22 N4 O2 S CC[C@@H](C....
112 3HVC ic50 = 600 nM GG5 C14 H10 F N3 c1cc(ccc1c....
113 2GFS ic50 = 0.7 uM PQB C19 H18 F N3 O4 c1cc(cc(c1....
114 5N63 - 8OW C21 H17 F N4 c1ccc(cc1)....
115 2NPQ Kd = 3.08 uM BOG C14 H28 O6 CCCCCCCCO[....
116 3IW6 Kd = 3.29 uM PP0 C23 H31 N3 O3 CCn1c(c(c(....
117 3S4Q ic50 = 4 nM NK0 C25 H23 N5 O2 Cc1ccc(cc1....
118 2BAJ Kd = 4 nM 1PP C20 H20 Cl2 N4 O CC(C)(C)c1....
119 3ROC - 29B C14 H10 F N3 c1cc(ccc1c....
120 3NWW ic50 = 7 nM 3NW C24 H34 N8 O S CCNC(=O)NC....
121 1W83 ic50 = 0.065 uM L11 C23 H25 Cl F N3 O3 c1cc(cnc1)....
122 3ZSH - 469 C27 H30 Cl F N4 O3 C[C@@H]1C[....
123 3IPH Ki = 0.0000251 mM G11 C21 H23 N3 O2 Cc1ccc(cc1....
124 3P7B ic50 = 0.018 uM P7B C25 H28 N4 O3 S CC(C)(C)c1....
125 3GCQ Kd = 342 nM 1BU C29 H30 N8 O Cc1cccc(c1....
126 4F9Y Ki = 184 nM LM3 C21 H18 N4 CN(C)c1cc(....
127 2BAL Kd = 490 nM PQA C21 H21 F N4 O2 c1cc(cc(c1....
128 3HUB Kd = 8.2 nM 469 C27 H30 Cl F N4 O3 C[C@@H]1C[....
129 4F9W Ki = 114 nM LM4 C21 H18 N4 CN(C)c1cc(....
130 3P5K ic50 = 0.076 uM P5K C24 H27 N3 O4 S2 CC(C)(C)c1....
131 2I0H ic50 = 9 nM 222 C27 H19 Cl2 F N4 O3 c1ccc2c(c1....
132 1ZYJ ic50 = 1.5 uM BI5 C19 H16 N2 O2 c1ccc(cc1)....
133 3K3I - JZJ C18 H16 Br N3 c1ccc2c(c1....
134 1WBT ic50 = 0.34 uM WBT C26 H25 F N4 O2 c1cc(cc2c1....
135 1BMK - SB5 C17 H16 F N5 c1cc(ccc1c....
136 3E92 Ki = 10 nM G6A C21 H21 N3 O2 Cc1ccc(cc1....
137 3P7A ic50 = 0.52 uM P7A C23 H27 N3 O3 S2 CC(C)(C)c1....
138 3NNX ic50 = 11 nM EDD C22 H23 Cl2 N5 O2 CC(C)(C)C1....
139 4EH4 - IRG C17 H16 N4 c1ccc(cc1)....
140 1KV1 Kd = 1.16 uM BMU C15 H19 Cl N4 O CC(C)(C)c1....
141 3KF7 ic50 = 40 nM L9G C22 H18 F2 N4 O Cc1ccc(cc1....
142 4KIN ic50 = 4.8 nM 1M8 C22 H19 Cl N2 O2 S Cc1ccc(cc1....
143 4AA4 ic50 = 9 nM QC0 C25 H25 N5 O3 Cc1ccc(cc1....
144 3E93 Ki = 1.4 nM 19B C30 H32 N4 O3 Cc1ccc(cc1....
145 4AAC ic50 = 16 nM AAV C24 H24 N6 O3 Cc1ccc(cc1....
146 4AA0 ic50 = 35 nM AA0 C30 H33 N7 O3 Cc1ccc(cc1....
147 1OZ1 ic50 = 6.5 nM FPH C18 H12 F N3 O c1cc2c(c(c....
148 5N64 - 8OH C19 H16 N4 S c1ccc(cc1)....
149 3IW8 Kd = 13.4 uM HIZ C19 H18 Cl F N4 O2 S c1ccc(cc1)....
150 3TTI ic50 = 0.006 uM KBI C21 H23 F3 N6 O2 c1c(cc(c(c....
151 3TTJ ic50 = 0.21 uM JBI C23 H23 F N6 O COc1ccc(cc....
152 1JNK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
153 4H3B Kd = 17.2 uM VAL VAL ARG PRO GLY SER LEU ASP LEU PRO n/a n/a
154 3KVX ic50 = 0.148 uM FMY C26 H27 F N8 O2 c1cc(ccc1/....
155 4H39 Kd = 0.8 uM PRO LYS ARG PRO THR THR LEU ASN LEU PHE n/a n/a
156 4AWI ic50 = 1 uM AQ2 C21 H25 N3 O4 S2 CC(C)c1cc2....
157 2O0U ic50 = 3.2 uM C0M C27 H28 N4 O2 S c1ccc2c(c1....
158 2P33 ic50 = 57 nM J07 C20 H23 Cl N6 O CCNC(=O)N1....
159 2ZDU - 446 C28 H23 Br N2 O6 COC(=O)C1=....
160 2B1P ic50 = 3 nM AIZ C26 H26 Cl N5 O3 CN(C)CCCC(....
161 2OK1 Ki = 0.55 uM 33A C21 H17 Cl N4 O c1ccc(cc1)....
162 3OXI ic50 = 2.2 uM SYY C12 H11 N O3 S2 COC(=O)c1c....
163 3OY1 ic50 = 0.016 uM 589 C28 H31 N5 O2 c1ccc2cc(c....
164 2ZDT - 46C C26 H20 Cl N O4 CCC(=O)C1=....
165 3ELJ - GS7 C22 H21 F N6 O4 S COc1cc(ccc....
166 3FI2 ic50 = 0.025 uM JK1 C26 H25 N5 O5 COc1cc(cc(....
167 4L7F ic50 = 160 nM 1V5 C26 H26 F N5 O2 c1cc(ccc1C....
168 2WAJ ic50 = 0.398 uM SNB C16 H13 Br Cl N O COc1cc2c(c....
169 4QTD ic50 = 1080 nM 38Z C33 H33 N9 O2 c1cnc(nc1)....
170 3G9L Ki = 0.74 uM J67 C25 H19 F N2 O4 c1ccc(cc1)....
171 4Y46 ic50 = 11 nM 4F2 C22 H32 N6 O2 CC(C)NC(=O....
172 1PMN ic50 = 7.1 nM 984 C25 H30 Cl2 N6 CCCn1c(c(n....
173 3FI3 ic50 = 12 nM JK2 C29 H25 F N4 O4 COc1cc(cc(....
174 2O2U ic50 = 4 uM 738 C16 H13 F N2 O S c1ccc(c(c1....
175 4W4V ic50 = 866 nM 3H8 C23 H19 Cl N6 O2 Cc1cc(ccn1....
176 3DA6 - BZ9 C28 H23 N7 O Cc1cc(c2cc....
177 2R9S ic50 = 0.15 uM 255 C24 H24 N4 O2 S CC(C)(C)NS....
178 4Y5H ic50 = 15 nM 519 C20 H30 N6 O2 CC(C)NC(=O....
179 4X21 Kd = 36 nM 3WH C20 H23 I N6 O CCNC(=O)N1....
180 3RTP ic50 = 7 nM 34I C18 H14 N6 O2 S c1ccc2c(c1....
181 3PZE - CFK C12 H11 N3 O2 S c1ccc(cc1)....
182 4Z9L ic50 = 1.6 nM 880 C27 H34 Cl2 N6 CCCn1c(c(n....
183 4WHZ ic50 < 1 nM 3NL C24 H23 Cl N8 O2 c1ccc(c(c1....
184 4W4Y ic50 = 3034 nM 3HQ C24 H22 N6 O2 Cc1ccc(cc1....
185 4W4W ic50 = 6630 nM 3HJ C23 H20 N6 O2 Cc1cc(ccn1....
186 3G90 Ki = 0.44 uM J72 C17 H12 F2 N2 O4 c1cc2c(cc1....
187 1PMV ic50 = 150 nM 537 C14 H8 N2 O c1ccc2c(c1....
188 3GC8 - B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
189 3GC9 - B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
190 4ZSL - 4QZ C17 H17 Cl N6 O C[C@@H](c1....
191 5BYZ ic50 = 0.042 uM 4WE C25 H32 F N7 O Cc1ncc(n1C....
192 4ZSJ ic50 = 2.3 uM 4R0 C13 H17 Cl N6 O Cc1cc(ccc1....
193 4ZSG - 4QX C12 H15 Cl N6 O CC(C)NC(=O....
194 4XP3 - DX4 C5 H5 N5 S c1[nH]c2c(....
195 4O6E ic50 = 1 nM 2SH C21 H25 Cl F N5 O3 c1cc(c(cc1....
196 5NHJ ic50 < 0.0003 uM 8XE C18 H21 N7 O2 Cn1c(ccn1)....
197 4QYY Kd = 0.05 uM 3G7 C25 H29 Cl N4 O4 CC(=O)c1cc....
198 4I5H Ki < 2 nM G17 C26 H21 F3 N4 O Cc1ccc(cc1....
199 4QTE Kd = 0.084 uM 390 C24 H20 Cl2 F N5 O2 Cc1cnc(nc1....
200 4XNE - TT4 C8 H9 N5 c1ccc(cc1)....
201 3QYW - 6PB C11 H8 Br N5 c1cc(cc(c1....
202 5BUE ic50 = 0.003 uM 4V8 C23 H21 N5 O c1ccc(cc1)....
203 2Z7L - S91 C20 H19 N5 O3 Cc1cccc(c1....
204 4ZXT - CAQ C6 H6 O2 c1ccc(c(c1....
205 1WZY ic50 = 0.56 uM F29 C21 H17 N7 C=CCn1c2c(....
206 5NHH ic50 < 0.00113 uM 8XH C19 H25 N5 O3 COCCN1CCc2....
207 4N4S - 2H1 C25 H24 N6 O Cc1cc(cc2c....
208 4QP8 ic50 = 0.28 uM 362 C14 H10 N6 c1cc(cnc1)....
209 4QP4 - 36O C11 H15 N5 c1[nH]c2c(....
210 4QP9 ic50 = 0.071 uM 35X C17 H16 N6 CCCn1cc(cn....
211 5BVE ic50 = 0.01 nM 4VG C25 H28 Cl N5 O3 c1cc(cc(c1....
212 5KE0 - 6S9 C20 H18 N6 O Cc1cc(ccn1....
213 4XOY - DX4 C5 H5 N5 S c1[nH]c2c(....
214 3QYZ - Z8B C10 H11 Br N8 O3 c1nc(c2c(n....
215 5BVF ic50 = 0.19 nM 4VJ C25 H28 Cl N5 O3 c1cc(cc(c1....
216 4XOZ - 620 C15 H16 N6 O c1ccc(cc1)....
217 5HD7 - 38Z C33 H33 N9 O2 c1cnc(nc1)....
218 4XRJ - 620 C15 H16 N6 O c1ccc(cc1)....
219 2OJJ Ki = 0.002 uM 82A C22 H17 Cl2 F N4 O2 c1cc(cc(c1....
220 4QTA Kd = 0.013 uM 38Z C33 H33 N9 O2 c1cnc(nc1)....
221 5NHO ic50 < 0.0003 uM 8XN C20 H25 N7 O2 Cc1cnc(nc1....
222 2OJG Ki = 2.3 uM 19A C16 H16 N4 O CN(C)C(=O)....
223 4XP0 - 42A C8 H5 N3 c1cc2c(c[n....
224 4QP2 Kd = 940 uM 36R C7 H5 Cl N2 O c1cc2c(cc1....
225 5NHF ic50 = 0.0012 uM 8X5 C23 H25 N5 O2 c1ccc(cc1)....
226 5BUJ ic50 = 0.005 uM 4VB C16 H15 N5 O c1cnccc1c2....
227 5BUI ic50 = 0.089 uM 4V9 C17 H15 F N4 c1ccnc(c1)....
228 4QP7 ic50 = 5.9 uM 363 C9 H7 N5 c1c[nH]c2c....
229 3ERK ic50 = 18 uM SB4 C18 H19 F N6 c1cc(ccc1c....
230 5V60 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
231 1TVO Ki = 0.14 uM FRZ C18 H13 N7 c1ccc(cc1)....
232 5BVD ic50 = 0.16 nM 4VF C24 H26 Cl N5 O3 c1cc(cc(c1....
233 4ZZN ic50 = 0.26 uM CQ8 C18 H21 Cl N4 O2 CNC(=O)c1c....
234 3SA0 - NRA C13 H8 O6 c1c(cc2c(c....
235 4ERK ic50 = 27 uM OLO C15 H18 N6 O Cn1cnc2c1n....
236 5U6I - 81Y C19 H22 N4 O2 CC(C)Oc1cc....
237 5NHV ic50 = 0.0028 uM 8QB C16 H19 N5 O2 c1cnc(nc1c....
238 3I5Z Ki = 2 nM Z48 C24 H23 N5 O2 Cc1cnc(nc1....
239 4N0S - DHC C9 H8 O4 c1cc(c(cc1....
240 5NHP ic50 = 0.023 uM 8XK C19 H23 N7 O2 Cn1c(ccn1)....
241 3I60 Ki < 2 nM E86 C24 H22 Cl N5 O2 Cc1cnc(nc1....
242 4XP2 - TT4 C8 H9 N5 c1ccc(cc1)....
243 1PME Ki = 0.76 nM SB2 C21 H16 F N3 O S C[S@](=O)c....
244 5NHL ic50 < 0.0003 uM 8XB C20 H25 N7 O2 Cc1cnc(nc1....
245 5HD4 - 38Z C33 H33 N9 O2 c1cnc(nc1)....
246 5K4I ic50 = 3.1 nM 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
247 2F9G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
248 2B9F - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
249 5AWM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
250 4EYM - 0RX C21 H20 N4 O3 c1cc(ccc1N....
251 5EKO ic50 = 15785 nM N17 C22 H18 N4 O2 Cc1cn(cn1)....
252 4EYJ - N61 C20 H23 N5 O2 CC(C)(C)c1....
253 1CM8 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
254 4QTB Kd = 0.084 uM 38Z C33 H33 N9 O2 c1cnc(nc1)....
255 2ZOQ ic50 = 0.9 uM 5ID C11 H13 I N4 O4 c1c(c2c(nc....
256 3NPC - B96 C31 H37 N5 O3 Cc1ccc(cc1....
257 3E7O ic50 = 120 nM 35F C20 H14 N6 O2 c1cc(cc(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 4R0; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 4R0 1 1
2 4QX 0.641791 1
3 4QZ 0.457831 0.943396
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5BYZ; Ligand: 4WE; Similar sites found: 388
This union binding pocket(no: 1) in the query (biounit: 5byz.bio1) has 31 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5N1X 8HH 0.00003851 0.6059 None
2 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.008045 0.43192 None
3 4JNJ BTN 0.007836 0.42429 None
4 2Z6C FMN 0.007121 0.41543 None
5 5V3D FCN 0.03905 0.40381 None
6 4WUJ FMN 0.005931 0.41903 1.36054
7 5HCN DAO 0.04719 0.40002 1.53257
8 2C49 ADN 0.002761 0.43789 1.65563
9 4UCC ZKW 0.02206 0.42096 1.71674
10 1N9L FMN 0.01165 0.40573 1.83486
11 3B1Q NOS 0.0052 0.42518 1.84049
12 4R78 AMP 0.01223 0.42696 1.94175
13 3G58 988 0.004239 0.446 2.01149
14 4ETZ C2E 0.02358 0.4121 2.0202
15 4WVW SLT 0.0009039 0.47742 2.08333
16 4JH6 FCN 0.02034 0.41546 2.17391
17 4ZS4 ATP 0.0009196 0.45563 2.28013
18 4GCZ FMN 0.009456 0.40985 2.29885
19 4EE7 PIS 0.01184 0.43724 2.30263
20 3H7J PPY 0.01911 0.40554 2.46914
21 2D6M LBT 0.03309 0.40631 2.51572
22 2GQS C2R 0.002544 0.44786 2.53165
23 2GQS ADP 0.02066 0.40056 2.53165
24 2PYW ADP 0.0005737 0.40058 2.58621
25 3SHR CMP 0.0183 0.41382 2.67559
26 2ZHL NAG GAL GAL NAG 0.005049 0.4377 2.7027
27 1GEG GLC 0.02192 0.42689 2.73438
28 4D4U FUC NDG GAL FUC 0.03449 0.40557 2.85714
29 4DO1 ANN 0.01025 0.4393 2.87356
30 2R5V HHH 0.01706 0.41153 2.87356
31 5MRH Q9Z 0.02675 0.40923 2.87356
32 3U1T MLI 0.0259 0.41136 2.91262
33 3WUR O4B 0.007432 0.45278 2.92398
34 3B00 16A 0.01848 0.40982 2.94118
35 2GJ5 VD3 0.005102 0.40067 3.08642
36 3P7N FMN 0.003655 0.42855 3.10078
37 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.005564 0.43562 3.11284
38 5I35 ANP 0.000253 0.49081 3.16092
39 4OCV ANP 0.00341 0.42991 3.16092
40 3X01 AMP 0.04324 0.40316 3.16092
41 2YRX AMP 0.04656 0.40146 3.16092
42 5F6U 5VK 0.01178 0.42716 3.18471
43 4NYT PC 0.02709 0.40618 3.22581
44 4ZXF 4S7 0.009058 0.40751 3.23529
45 4RDL FUC GAL NDG FUC 0.04348 0.40385 3.24675
46 5UGW GSH 0.002307 0.42544 3.42857
47 4GYI ADP 0.0008232 0.47654 3.44828
48 3VV1 GAL FUC 0.004982 0.45345 3.44828
49 5MW8 ATP 0.0002609 0.41615 3.44828
50 2JIG PD2 0.02355 0.41213 3.57143
51 4B1L FRU 0.01474 0.42523 3.63636
52 4RW3 TDA 0.0123 0.45403 3.64238
53 4RW3 PLM 0.02651 0.42962 3.64238
54 3EW2 BTN 0.00552 0.4402 3.7037
55 4IAW LIZ 0.0291 0.40354 3.7234
56 3TDC 0EU 0.02839 0.41506 3.73563
57 3SDV 911 0.02445 0.40032 3.73563
58 1DZK PRZ 0.01952 0.40174 3.82166
59 3NZ1 3NY 0.02291 0.41652 3.83142
60 1SN0 T44 0.01551 0.4136 3.84615
61 5CDH TLA 0.04487 0.40084 3.86905
62 1SGJ OAA 0.01726 0.4066 3.87324
63 4GK9 MAN BMA MAN MAN MAN 0.01943 0.41984 3.94265
64 3AKK ADP 0.00783 0.41356 4
65 4UBS DIF 0.04073 0.41093 4.02299
66 3VSS FRU 0.03744 0.40558 4.02299
67 5ML3 DL3 0.001813 0.41806 4.02685
68 3E3U NVC 0.007687 0.42469 4.06091
69 5USZ SKE 0.00001123 0.50616 4.15225
70 3VPC ADP 0.007159 0.40892 4.25532
71 1ZP9 ATP 0.00014 0.50852 4.26357
72 3RE4 TO1 0.000141 0.40932 4.26357
73 4FE2 AIR 0.006895 0.43531 4.31373
74 4FE2 ADP 0.01755 0.41092 4.31373
75 5V4R MGT 0.005101 0.46117 4.32099
76 1NKI PPF 0.02333 0.41652 4.44444
77 3ML5 AZM 0.0447 0.40247 4.46097
78 1N5S ADL 0.0153 0.40676 4.46429
79 2WKQ FMN 0.0129 0.40372 4.51807
80 2PR5 FMN 0.01003 0.40868 4.54545
81 5GZ9 ANP 0.000001624 0.48898 4.59016
82 1OLM VTQ 0.002858 0.41088 4.5977
83 2HRL SIA GAL SIA BGC NGA CEQ 0.002831 0.4599 4.72441
84 2CHT TSA 0.03474 0.40721 4.72441
85 5DQY BEZ 0.02022 0.42379 4.7619
86 4QA8 PJZ 0.003967 0.41378 4.80349
87 1XM4 PIL 0.007451 0.42936 4.88506
88 3TII ANP 0.01733 0.41502 4.88506
89 5E58 CPZ 0.02616 0.40794 4.88506
90 2BKK ADP 0.0009278 0.47398 4.92424
91 4QPW XYP XYP XYP 0.003201 0.41017 4.92958
92 1TQP ATP 0.001569 0.43064 4.96454
93 3P9T TCL 0.00776 0.43271 5.02283
94 4MNS 2AX 0.006794 0.40546 5.03145
95 4V3I ASP LEU THR ARG PRO 0.02735 0.41599 5.05837
96 2WR1 NAG 0.0006811 0.48485 5.17241
97 3GL0 HXX 0.003687 0.44444 5.17241
98 5NCY 8TK 0.0003379 0.44098 5.17241
99 4O4Z N2O 0.0342 0.41157 5.19481
100 3OYW TDG 0.01106 0.43384 5.22388
101 4OUC 5ID 0.00001078 0.56211 5.32213
102 5DMZ ADP 0.000006536 0.55896 5.45977
103 4UWH JXM 0.003479 0.44131 5.45977
104 3I0O ADP 0.00275 0.45548 5.60472
105 1IA9 ANP 0.001549 0.4454 5.71429
106 3OCP CMP 0.02078 0.411 5.7554
107 2GC0 PAN 0.004799 0.4268 5.85106
108 4AVB CMP 0.01999 0.40812 6.00601
109 4YVN EBS 0.01811 0.42396 6.03448
110 3UPY FOM 0.01934 0.41249 6.03448
111 3UDZ ADP 0.0002497 0.40166 6.32184
112 2OBM ADP 0.04016 0.4054 6.34006
113 4RYV ZEA 0.000993 0.47781 6.45161
114 4X5S AZM 0.0356 0.40625 6.46552
115 1TZD ADP 0.01767 0.42501 6.54545
116 5DCH 1YO 0.02149 0.42119 6.77083
117 1Y75 NAG 0.0337 0.40397 6.77966
118 1W2D ADP 0.00474 0.44354 6.79245
119 5FUI APY 0.002548 0.46665 6.81818
120 1J3R 6PG 0.001929 0.46326 6.84211
121 2CDO GAL AAL GAL AAL GAL AAL 0.001446 0.48236 6.875
122 3N7S 3N7 0.02276 0.4252 6.95652
123 3R9V DXC 0.02245 0.41991 6.99301
124 4DFU QUE 0.02403 0.41583 7.14286
125 1YRO UDP 0.03217 0.40483 7.31707
126 5OCA 9QZ 0.0006312 0.50596 7.56302
127 1BHX ASP PHE GLU GLU ILE 0.0002857 0.50509 7.61905
128 1OGX EQU 0.00235 0.44953 7.63359
129 4OAV ACP 0.000003308 0.57951 7.75862
130 3AVR OGA 0.04761 0.40204 7.75862
131 5OO5 UUA 0.02084 0.40039 8.06452
132 4ZU4 4TG 0.003725 0.43577 8.10811
133 4Z28 BTN 0.004902 0.4428 8.20895
134 5KEW 6SB 0.003563 0.46336 8.33333
135 4BKS X6C 0.03139 0.40961 8.64198
136 5FPX GLY SER SER HIS HIS HIS HIS HIS 0.01386 0.4023 8.84956
137 4K55 H6P 0.001548 0.47371 8.87097
138 3RET SAL 0.006804 0.42726 8.91089
139 3RET PYR 0.006804 0.42726 8.91089
140 4OCT AKG 0.01574 0.41714 9.00901
141 1P0Z FLC 0.02693 0.41317 9.16031
142 4Q5H ANP 0.0002466 0.48627 9.21053
143 1VDN ACE ALA ALA PRO ALA MCM 0.04447 0.40249 9.25926
144 3KDM TES 0.04063 0.40614 9.33333
145 2OVD DAO 0.01432 0.43027 9.34066
146 4LRJ ANP 0.0000711 0.40951 9.46746
147 3TDV GDP 0.0004429 0.47454 9.47712
148 4WH9 3M8 0.02786 0.4059 9.83607
149 5TFZ 7BC 0.007933 0.43672 10
150 5KTI TRE 6X6 0.02441 0.41453 10.0671
151 4WW7 AMP 0.00002001 0.4505 10.3448
152 3LLZ GAL NGA 0.03084 0.41071 10.5263
153 2VQD AP2 0.009579 0.40643 10.5603
154 3Q60 ATP 0.00006182 0.51964 10.6322
155 4MA6 28E 0.01216 0.43164 10.828
156 3BRN SRO 0.02979 0.41192 10.828
157 3SQP 3J8 0.01453 0.4344 10.9195
158 5E5U 1PS 0.006957 0.4328 10.9848
159 5AIG VPR 0.003957 0.4475 11.2
160 5C03 AGS 0.000298 0.48248 11.6959
161 4I9B 1KA 0.00947 0.4079 11.7816
162 1ECM TSA 0.02156 0.41413 11.9266
163 1Y7P RIP 0.002404 0.41067 12.1076
164 4WOV 3SM 0.0005759 0.48418 12.6183
165 5T7I LAT NAG GAL 0.003337 0.46218 12.9032
166 2VWA PTY 0.02196 0.42213 14.8515
167 5JAX 6J7 0.00907 0.41752 15.5556
168 4I94 ANP 0.0000165 0.42537 16
169 4WOE ADP 0.01637 0.42573 16.092
170 4MUV PCG 0.007641 0.42104 16.1972
171 5E89 TD2 0.005329 0.42843 16.5468
172 5SVV FMN 0.0128 0.40083 16.7883
173 3VHE 42Q 0.00001098 0.49792 17.2414
174 2QLU ADE 0.000002573 0.64589 17.8344
175 4CYI ATP 0.0004077 0.4037 18.1034
176 2Y69 CHD 0.02668 0.41317 18.6047
177 4L9I 8PR 0.0000001595 0.64153 19.246
178 3HAV ATP 0.02107 0.42038 19.7324
179 4O1P ANP 0.00000434 0.4582 20.1149
180 4FL3 ANP 0.00000004064 0.63664 20.977
181 4XH0 ADP 0.00005969 0.55856 21.8391
182 5VC5 96M 0.0000004162 0.5327 22.1453
183 1EPB REA 0.005394 0.42819 22.561
184 4BTK DTQ 0.00007579 0.41689 23.4421
185 5W4W 9WG 0.000003281 0.51356 23.8671
186 4KBA 1QM 0.00001684 0.49919 23.8671
187 5M06 ADP 0.00008248 0.51958 24.2754
188 2CSN CKI 0.003028 0.4254 25.2525
189 4NFN 2KC 0.00002093 0.42417 25.5663
190 1OPK P16 0.000111 0.45602 25.8621
191 3HMO STU 0.0000006937 0.4631 26.9006
192 4E93 GUI 0.000007498 0.49358 27.0115
193 3PP0 03Q 0.000002426 0.5375 27.5148
194 4WNK 453 0.00000001609 0.59485 27.5862
195 2R5T ANP 0.0000005623 0.58712 27.5862
196 4Y93 746 0.00009602 0.47716 27.5862
197 1H0A I3P 0.03441 0.41066 27.8481
198 2H8H H8H 0.000006582 0.55882 27.8736
199 2PZI AXX 0.0003997 0.49199 27.8736
200 4OH4 ANP 0.000001116 0.47335 27.9279
201 3GNI ATP 0.000002925 0.56209 28.1609
202 1Y57 MPZ 0.000004112 0.54396 28.1609
203 5LPZ ADP 0.0000001213 0.63878 28.3133
204 3DLS ADP 0.000004806 0.43668 28.3582
205 3C1X CKK 0.0002326 0.47356 28.4483
206 3KRL KRL 0.00003034 0.51196 28.9552
207 3UIM ANP 0.00002286 0.53389 29.1411
208 5HCY 60D 0.000000005227 0.64171 29.3051
209 5LI9 ACP 0.0000004885 0.60352 29.3103
210 4P5Z Q7M 0.00001254 0.45916 29.3103
211 4X7Q 3YR 0.00000003374 0.6644 29.4872
212 5U6C 7YS 0.00002084 0.51904 29.5238
213 3LXN MI1 0.00000004364 0.64291 29.5597
214 4N70 2HX 0.00000009471 0.59837 29.5732
215 3VRY B43 0.000003485 0.53624 29.5977
216 4BHN BH9 0.000009273 0.53991 29.6407
217 3E8N ATP 0.000000507 0.47941 29.912
218 3E8N VRA 0.000000507 0.47941 29.912
219 3H9R TAK 0.00001292 0.58087 30
220 4Y85 499 0.00001878 0.42889 30.1205
221 2OO8 RAJ 0.004178 0.41909 30.2839
222 3TXO 07U 0.0000007776 0.4644 30.4598
223 5UIU 8CG 0.0000003244 0.54641 30.6502
224 3GQI ACP 0.0000000234 0.67172 30.6748
225 4K33 ACP 0.0000002268 0.49676 30.7692
226 4U0I 0LI 0.0003242 0.43851 30.7937
227 4Y8D 49J 0.000001501 0.58841 30.8824
228 3CY2 MB9 0.000001939 0.55785 30.8917
229 4ASE AV9 0.00007243 0.4741 31.0345
230 5VCV 1N1 0.0000001213 0.60246 31.1897
231 4CLI 5P8 0.000009439 0.51349 31.1927
232 2X2M X2M 0.00000007994 0.52334 31.2102
233 3V8S 0HD 0.0000005231 0.61724 31.3218
234 5EOB 5QQ 0.0000001479 0.59756 31.348
235 3KN5 ANP 0.00001684 0.41306 31.3846
236 5LPB ADP 0.000007085 0.43235 31.4189
237 2PVF ACP 0.00000002466 0.67971 31.4371
238 4GJ3 0XP 0.000000106 0.56965 31.457
239 5JFS 6K0 0.000004494 0.52185 31.4935
240 3LXK MI1 0.00000004055 0.56716 31.4985
241 3FHI ANP 0.00000508 0.48787 31.6092
242 4OTH DRN 0.00000005907 0.62959 31.6716
243 2QCS ANP 0.000004417 0.49022 31.8966
244 4WB7 ATP 0.00002703 0.45646 31.8966
245 5TO8 7FM 0.00003216 0.48717 31.9149
246 5NKB 8ZT 0.0000009083 0.47961 32.0261
247 5HVJ ANP 0.000004305 0.61966 32.0635
248 1RE8 BD2 0.0000001163 0.59181 32.1839
249 3IDB ANP 0.00001034 0.5269 32.1839
250 4YMJ 4EJ 0.0000558 0.55814 32.2368
251 4WB6 ATP 0.000004801 0.48908 32.4713
252 4E1Z 0MX 0.000002341 0.55437 32.646
253 3PVW QRX 0.00000009341 0.5945 32.7586
254 5UKL SIX 0.0000001551 0.54793 32.7586
255 5UR1 YY9 0.000007183 0.51678 32.7974
256 3ORK AGS 0.00002146 0.50386 32.7974
257 5LVP ATP 0.000002076 0.44323 33.119
258 2GU8 796 0.000000007572 0.65127 33.2344
259 5TA6 79D 0.00000468 0.5212 33.3333
260 5JKG 6LF 0.00002807 0.48802 33.4405
261 5MJA 7O3 0.000001433 0.45611 33.4426
262 3RI1 3RH 0.00000006896 0.5547 33.5463
263 5KO1 6UY 0.000001244 0.59952 33.5689
264 4TWP AXI 0.00001566 0.42857 33.5793
265 1JPA ANP 0.0007244 0.47736 33.6538
266 3ALN ANP 0.000002459 0.47634 33.945
267 4XLI 1N1 0.000006927 0.5644 33.9552
268 5CEO 50D 0.00004945 0.42045 34
269 3BZ3 YAM 0.00001609 0.40251 34.058
270 4AT3 LTI 0.0001036 0.46062 34.1137
271 1BYG STU 0.0000002057 0.64489 34.1727
272 4AG8 AXI 0.00002464 0.45765 34.1772
273 4M69 ANP 0.00002884 0.51811 34.1853
274 3G5D 1N1 0.00000006867 0.6124 34.2657
275 2XVD AS6 0.000002051 0.53051 34.4371
276 4G31 0WH 0.0000452 0.45936 34.4482
277 4EWH T77 0.000001034 0.54716 34.5455
278 3PLS ANP 0.0000002886 0.6294 34.5638
279 5JGA 6KC 0.000000175 0.55306 34.6032
280 4C2V YJA 0.00000001722 0.60521 34.7368
281 4L3L 5FI 0.000003517 0.5084 34.8684
282 4CSV STI 0.00045 0.45714 34.9091
283 5LI1 ANP 0.0000003668 0.50337 35.0575
284 1U59 STU 0.0000008998 0.59866 35.1916
285 2Y6O 1N1 0.00001114 0.45758 35.3952
286 5FBN 5WF 0.0000007859 0.54272 35.4244
287 4C2W ANP 0.00000154 0.43787 35.4839
288 4EUU BX7 0.00002692 0.49539 35.7367
289 4RFM 3P6 0.00003043 0.41443 36.0902
290 3SRV S19 0.0000004178 0.47596 36.1011
291 5UOX 8GY 0.00000522 0.54512 36.1624
292 3SXS PP2 0.000004267 0.4655 36.194
293 4D2S DYK 0.0000002435 0.45483 36.2069
294 1U5R ATP 0.0004899 0.40021 36.2069
295 5EYK 5U5 0.00000003361 0.60608 36.2319
296 3KRR DQX 0.0000004393 0.58779 36.2712
297 3NW7 LGV 0.00000238 0.53984 36.4821
298 5HES 032 0.0000006423 0.49369 36.4821
299 4NW6 2NS 0.0000003366 0.54298 36.5325
300 4F4P 0SB 0.000000654 0.5762 36.63
301 2WQN ADP 0.00001786 0.55848 36.7742
302 4YZC STU 0.000000006856 0.62556 37.069
303 4ITH RCM 0.007278 0.4086 37.0748
304 1K3A ACP 0.00001038 0.57008 37.1237
305 5T8O 76Z 0.0000006174 0.59199 37.2493
306 2A19 ANP 0.000002007 0.61366 37.3239
307 4U44 3D9 0.000006246 0.44714 37.3494
308 4IDT T28 0.00000058 0.47136 37.3563
309 5DRB 5FJ 0.00001087 0.43052 37.457
310 3BU5 ATP 0.0000001379 0.49711 37.5817
311 3C0G 3AM 0.000005499 0.58366 37.6437
312 3EKK GS2 0.0000001937 0.52509 37.785
313 3GGF GVD 0.0000002573 0.47209 37.8738
314 2ZV2 609 0.000002372 0.61 37.9195
315 2YAB AMP 0.000001613 0.58009 37.931
316 4JR7 GNP 0.000009361 0.44076 38.2184
317 4YZN 4K5 0.0000001794 0.60186 38.3275
318 2HK5 1BM 0.0000002648 0.50073 38.5185
319 2OFV 242 0.00001138 0.47075 38.6282
320 4I6H 1C8 0.0001566 0.49536 38.7931
321 2Z7R STU 0.00000005759 0.63007 38.9408
322 4WNP 3RJ 0.0000003306 0.64379 39.0244
323 5DEY 59T 0.0000000847 0.46761 39.0572
324 4BFM ANP 0.0000001203 0.62342 39.2216
325 3HZT J60 0.00004029 0.54798 39.3678
326 4A4X JUP 0.000007412 0.48313 39.4265
327 3SLS ANP 0.000001167 0.48922 39.4737
328 2RIO ADP 0.00000009772 0.49733 39.6552
329 4CQE CQE 0.00001317 0.4529 39.9281
330 4XV1 904 0.00001401 0.49332 40.0685
331 3IGO ANP 0.0000002533 0.60215 40.2299
332 4JDI ANP 0.0000003925 0.49602 40.4624
333 5N87 N66 0.0000000008168 0.65886 40.5751
334 1VJY 460 0.0000003101 0.55418 40.5941
335 3SXF BK5 0.000003027 0.49598 40.8046
336 4QMN DB8 0.000002758 0.49159 40.9677
337 5IH9 6BF 0.0000002882 0.56123 41.194
338 5H2U 1N1 0.0001336 0.49855 41.1985
339 3QCQ 3Q0 0.00000001132 0.40864 41.3462
340 1Q8Y ADP 0.0000002675 0.50316 41.3793
341 5HX8 66P 0.000002688 0.53571 41.3907
342 3M2W L8I 0.0000008851 0.45468 41.4716
343 3TKI S25 0.0000009925 0.56286 41.4861
344 5DA3 58V 0.000002672 0.60739 41.5094
345 3MVH WFE 0.000000108 0.56375 41.5205
346 2HY0 306 0.00001846 0.55777 41.6149
347 2WU6 DKI 0.000001587 0.49162 41.6667
348 5A6N U7E 0.000004252 0.45856 41.6961
349 5AX9 4KT 0.000004918 0.4523 41.8831
350 4IJP 1EH 0.00000002551 0.53042 41.954
351 3FHR P4O 0.00009751 0.49965 41.9643
352 5MY8 RXZ 0.00004354 0.45218 42.5287
353 5DH3 5BS 0.00001372 0.53239 42.5397
354 2V7O DRN 0.0000005734 0.43583 42.5595
355 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.000000009521 0.47508 42.6901
356 2JDR L20 0.000000009521 0.47508 42.6901
357 4USF 6UI 0.0002321 0.42099 43.0921
358 1XJD STU 0.0000007308 0.59562 43.4783
359 2F57 23D 0.00004427 0.53258 43.8486
360 5DBX ANP 0.000006219 0.42113 43.9024
361 5X8I SQZ 0.0000007429 0.60249 43.9306
362 4F9C 0SX 0.000005998 0.43935 43.9655
363 4FG8 ATP 0.000004119 0.46647 44.127
364 2VZ6 FEF 0.00003422 0.54456 44.4089
365 5G1X ADP 0.0000004022 0.62261 44.5614
366 5L8L ADP 0.000001892 0.61495 44.5614
367 5LXM ADP 0.000001162 0.60091 44.8763
368 5JZJ AN2 0.00000002607 0.50886 45.4545
369 2PVN P63 0.00001648 0.49529 45.4545
370 2XK9 XK9 0.00004217 0.51491 45.9627
371 1PHK ATP 0.0000001676 0.50065 45.9732
372 3PE2 E1B 0.0004819 0.44842 45.9941
373 5LXC 7AA 0.000001608 0.45181 46.2644
374 4YLL 4E3 0.00000003777 0.54365 46.5517
375 5EW9 5VC 0.000001738 0.58881 46.8635
376 2X4Z X4Z 0.00000001615 0.57577 47.2973
377 3E5A VX6 0.00001003 0.51741 47.3881
378 4NST ADP 0.0000005118 0.60996 47.4138
379 2VN9 GVD 0.00001468 0.40139 47.5083
380 2YAK OSV 0.00000009304 0.57719 47.7193
381 4CRL C1I 0.000000254 0.53992 48.2759
382 3F7Z 34O 0.000001418 0.47418 48.2759
383 3ZRM ZRM 0.00004287 0.42376 48.2759
384 4NM5 ADP 0.0000004561 0.58461 48.5632
385 2JLD AG1 0.0000001 0.57484 48.5632
386 3GC0 AMP 0.0000226 0.55343 48.6322
387 2WEI VGG 0.00001194 0.55999 48.7805
388 5EFQ ADP 0.0000001567 0.49595 49.2795
389 4KS7 X4Z 0.000005403 0.53891 50
390 3DAK ANP 0.00001113 0.43129 50
Feedback