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Receptor
PDB id Resolution Class Description Source Keywords
4ZBY 1.7 Å EC: 3.2.2.27 FAMILY 4 URACIL-DNA GLYCOSYLASE FROM SULFOLOBUS TOKODAII (UR COMPLEX FORM) SULFOLOBUS TOKODAII STR. 7 URACIL-DNA GLYCOSYLASE DNA REPAIR HYDROLASE
Ref.: CRYSTAL STRUCTURE OF FAMILY 4 URACIL-DNA GLYCOSYLAS SULFOLOBUS TOKODAII AND A FUNCTION OF TYROSINE 170 BINDING FEBS LETT. V. 589 2675 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SF4 A:201;
Part of Protein;
none;
submit data
351.64 Fe4 S4 [S]12...
MES A:203;
Invalid;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
URA A:202;
Valid;
none;
submit data
112.087 C4 H4 N2 O2 C1=CN...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ZBY 1.7 Å EC: 3.2.2.27 FAMILY 4 URACIL-DNA GLYCOSYLASE FROM SULFOLOBUS TOKODAII (UR COMPLEX FORM) SULFOLOBUS TOKODAII STR. 7 URACIL-DNA GLYCOSYLASE DNA REPAIR HYDROLASE
Ref.: CRYSTAL STRUCTURE OF FAMILY 4 URACIL-DNA GLYCOSYLAS SULFOLOBUS TOKODAII AND A FUNCTION OF TYROSINE 170 BINDING FEBS LETT. V. 589 2675 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4ZBY - URA C4 H4 N2 O2 C1=CNC(=O)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4ZBY - URA C4 H4 N2 O2 C1=CNC(=O)....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 4ZBY - URA C4 H4 N2 O2 C1=CNC(=O)....
2 1UI0 Ki = 88 nM URA C4 H4 N2 O2 C1=CNC(=O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: URA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 URA 1 1
2 TUL 0.5 0.725
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ZBY; Ligand: URA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4zby.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
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