Receptor
PDB id Resolution Class Description Source Keywords
4YMH 1.88 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF SAH-BOUND PODOSPORA ANSERINA METHYLTRAN PAMTH1 PODOSPORA ANSERINA TRANSFERASE METHYLATION
Ref.: STRUCTURE AND BIOPHYSICAL CHARACTERIZATION OF THE S-ADENOSYLMETHIONINE-DEPENDENT O-METHYLTRANSFERASE PUTATIVE ENZYME ACCUMULATING DURING SENESCENCE OF P ANSERINA. J.BIOL.CHEM. V. 290 16415 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:1001;
B:1001;
D:1001;
C:1001;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Kd = 3.2 uM
384.411 C14 H20 N6 O5 S c1nc(...
PEG B:1003;
B:1002;
A:1002;
D:1002;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YMH 1.88 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF SAH-BOUND PODOSPORA ANSERINA METHYLTRAN PAMTH1 PODOSPORA ANSERINA TRANSFERASE METHYLATION
Ref.: STRUCTURE AND BIOPHYSICAL CHARACTERIZATION OF THE S-ADENOSYLMETHIONINE-DEPENDENT O-METHYLTRANSFERASE PUTATIVE ENZYME ACCUMULATING DURING SENESCENCE OF P ANSERINA. J.BIOL.CHEM. V. 290 16415 2015
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 4YMH Kd = 3.2 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4YMG Kd = 21 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 4YMH Kd = 3.2 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4YMG Kd = 21 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 4YMH Kd = 3.2 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4YMG Kd = 21 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YMH; Ligand: SAH; Similar sites found: 486
This union binding pocket(no: 1) in the query (biounit: 4ymh.bio2) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5T2U NAP 0.01278 0.4015 None
2 1XSE NDP 0.002323 0.44216 0.833333
3 1YXM ADE 0.01052 0.41911 0.833333
4 4YAG NAI 0.004036 0.43332 1.25
5 3NUG NAD 0.002685 0.42879 1.25
6 5JCM NAD 0.01452 0.42265 1.25
7 5JCM ISD 0.01452 0.42265 1.25
8 5JCM FAD 0.0141 0.42265 1.25
9 3DXY SAM 0.0008389 0.46258 1.37615
10 5DM1 5D7 0.0006058 0.4673 1.66667
11 5DM1 SAH 0.0005704 0.4673 1.66667
12 4FC7 COA 0.001992 0.44722 1.66667
13 4FC7 NAP 0.001992 0.44722 1.66667
14 2A92 NAI 0.00462 0.41977 1.66667
15 1XKQ NDP 0.00561 0.41728 1.66667
16 3QWI NAP 0.00866 0.40897 1.66667
17 3QWI CUE 0.01385 0.40897 1.66667
18 4M38 SAH 0.00002397 0.50019 2.08333
19 1V59 FAD 0.0002988 0.48778 2.08333
20 3GCZ SAM 0.0001397 0.4591 2.08333
21 1PR9 NAP 0.000711 0.45674 2.08333
22 1QO8 FAD 0.001733 0.44997 2.08333
23 1KPG SAH 0.0004895 0.44758 2.08333
24 1KPH SAH 0.0006139 0.44345 2.08333
25 1N2X SAM 0.000447 0.43558 2.08333
26 4HXY NDP 0.002007 0.43431 2.08333
27 1V59 NAD 0.0001903 0.43124 2.08333
28 4M37 SAH 0.004734 0.43112 2.08333
29 5ITV NAI 0.002503 0.43012 2.08333
30 2Y6Q FAD 0.00339 0.42566 2.08333
31 2Y6Q I7T 0.00713 0.42566 2.08333
32 2PZM UDP 0.00836 0.41987 2.08333
33 2PZM NAD 0.00836 0.41987 2.08333
34 2OBF SAH 0.008082 0.41962 2.08333
35 2OBF F83 0.008082 0.41962 2.08333
36 1U7T TDT 0.01022 0.41406 2.08333
37 2YY7 NAD 0.006875 0.41095 2.08333
38 5UAO FAD 0.01264 0.40702 2.08333
39 2BZG SAH 0.0006978 0.43098 2.15517
40 4MO2 FDA 0.0004826 0.46934 2.17391
41 4MO2 FAD 0.0008687 0.45913 2.17391
42 3A4T SFG 0.00001172 0.50395 2.5
43 5KOK S9T 0.000102 0.49525 2.5
44 5KOK SAH 0.00002964 0.49094 2.5
45 1GET FAD 0.000608 0.48895 2.5
46 1GET NAP 0.0006512 0.48895 2.5
47 4BLW SAH 0.0001725 0.47417 2.5
48 4BLW AMP 0.0003542 0.47141 2.5
49 5KOK R9T 0.0004904 0.46382 2.5
50 3D3W NAP 0.0006506 0.45843 2.5
51 2FK8 SAM 0.0002537 0.45749 2.5
52 1VQW FAD 0.0008451 0.45344 2.5
53 1GY8 NAD 0.0007572 0.45277 2.5
54 2GVC FAD 0.001068 0.44898 2.5
55 5MBX FAD 0.004555 0.44031 2.5
56 5MBX SP5 0.004555 0.44031 2.5
57 3UOY NAP 0.007629 0.43724 2.5
58 3UOY FAD 0.007629 0.43724 2.5
59 5M67 NAD 0.005521 0.43246 2.5
60 5M67 ADE 0.005564 0.4323 2.5
61 5M67 3D1 0.005734 0.4317 2.5
62 3ZNN FAD 0.01239 0.4214 2.5
63 3ZNN 4WL 0.01239 0.4214 2.5
64 1KEW NAD 0.01287 0.417 2.5
65 1UP7 NAD 0.004321 0.41275 2.5
66 4DSG FAD 0.02469 0.40918 2.5
67 4DSG UDP 0.02469 0.40918 2.5
68 1XCL SAH 0.0000002823 0.60419 2.55319
69 5MX4 HPA 0.008969 0.43063 2.57511
70 3NTA FAD 0.003254 0.43346 2.78746
71 3NT6 FAD 0.006344 0.42046 2.78746
72 3QOX SAH 0.000001155 0.56024 2.91667
73 1QAN SAH 0.000003166 0.53936 2.91667
74 1Q0S SAH 0.00001002 0.52291 2.91667
75 5MW4 5JU 0.00007332 0.50973 2.91667
76 2ZIF SAM 0.00001843 0.49929 2.91667
77 5BVA FAD 0.0007934 0.46741 2.91667
78 3GD4 FAD 0.001995 0.45938 2.91667
79 3GD4 NAD 0.003143 0.45936 2.91667
80 3AB1 FAD 0.001184 0.45534 2.91667
81 2PWY SAH 0.002363 0.45032 2.91667
82 2CDU FAD 0.001614 0.44479 2.91667
83 3QVP FAD 0.002708 0.44216 2.91667
84 2RGJ FAD 0.001651 0.44066 2.91667
85 3NJ4 AFX 0.0172 0.4381 2.91667
86 3NJ4 NAD 0.0172 0.4381 2.91667
87 1GPE FAD 0.003698 0.43786 2.91667
88 4BV6 FAD 0.003225 0.43675 2.91667
89 5FTW SAH 0.0009881 0.43287 2.91667
90 2BD0 NAP 0.002927 0.42846 2.91667
91 2B4R AES 0.004644 0.4171 2.91667
92 1U1I NAD 0.0063 0.41623 2.91667
93 2B4R NAD 0.005313 0.41585 2.91667
94 1LVL FAD 0.03795 0.41457 2.91667
95 2CDU ADP 0.002313 0.40457 2.91667
96 3RIY NAD 0.009029 0.40452 2.91667
97 5A3B APR 0.007921 0.40295 2.91667
98 4R6W SAH 0.0003288 0.4022 2.91667
99 1P1C SAH 0.0000008131 0.56667 3.01508
100 1G55 SAH 0.0000009871 0.55117 3.33333
101 5E1M SAH 0.00003212 0.51738 3.33333
102 5E1M PRO PRO LYS ARG ILE ALA 0.00003212 0.51738 3.33333
103 4ONQ SFG 0.00005283 0.49605 3.33333
104 5CUQ NSC 0.0001303 0.48762 3.33333
105 5JJR SAH 0.0001524 0.47606 3.33333
106 1G60 SAM 0.0001125 0.46777 3.33333
107 3A25 SAM 0.00007792 0.46652 3.33333
108 4YUW S4M 0.004736 0.46141 3.33333
109 2P41 SAH 0.0001211 0.46141 3.33333
110 4YUW 4JU 0.004835 0.46141 3.33333
111 4M52 FAD 0.001014 0.46052 3.33333
112 3EVG SAH 0.0002217 0.45144 3.33333
113 1PN0 FAD 0.002987 0.44389 3.33333
114 1PN0 IPH 0.00312 0.44389 3.33333
115 1L1E SAH 0.0006449 0.44059 3.33333
116 2WSB NAD 0.004395 0.42967 3.33333
117 2AOT SAH 0.0003493 0.42935 3.33333
118 5THQ NDP 0.0027 0.42734 3.33333
119 1JQD SAH 0.0029 0.42598 3.33333
120 5J60 FAD 0.00666 0.42153 3.33333
121 4CQM NAP 0.004337 0.41839 3.33333
122 3O7W SAM 0.0006734 0.41675 3.33333
123 4EIP FAD 0.01224 0.41486 3.33333
124 4EIP K2C 0.01224 0.41486 3.33333
125 1KYQ NAD 0.002713 0.40346 3.33333
126 2PS1 ORO 0.01139 0.41697 3.53982
127 3DMH GMP 0.00008055 0.49013 3.75
128 1X87 NAD 0.00005502 0.4895 3.75
129 3DMH SAM 0.00004934 0.48712 3.75
130 2RAB FAD 0.0003247 0.48508 3.75
131 2RAB NAD 0.0007332 0.48508 3.75
132 4TXI FAD 0.0002796 0.47311 3.75
133 3CH6 NAP 0.001281 0.47069 3.75
134 3CH6 311 0.001281 0.47069 3.75
135 2BRY FAD 0.0005044 0.46329 3.75
136 4RDH AMP 0.0008104 0.45342 3.75
137 4YNU LGC 0.002066 0.45214 3.75
138 4YNU FAD 0.001716 0.45214 3.75
139 3GDN HBX 0.002279 0.45189 3.75
140 3GDN FAD 0.001571 0.45189 3.75
141 4J56 FAD 0.002222 0.44703 3.75
142 4PIO SAH 0.001483 0.44398 3.75
143 4PIO AVI 0.00152 0.44223 3.75
144 2WK1 SAH 0.003588 0.43845 3.75
145 3AYI HCI 0.00794 0.42829 3.75
146 3AYI FAD 0.007648 0.42829 3.75
147 3GMB FAD 0.005446 0.41903 3.75
148 4RDI ATP 0.001368 0.41903 3.75
149 4D79 ATP 0.001718 0.41525 3.75
150 1LLU NAD 0.007071 0.41401 3.75
151 3ABI NAD 0.00813 0.40651 3.75
152 2VYN NAD 0.008418 0.40455 3.75
153 1K3T BRZ 0.01118 0.40407 3.75
154 2V6G NAP 0.01048 0.40293 3.75
155 4J7U NAP 0.01548 0.40677 3.81944
156 4J7U YTZ 0.01548 0.40677 3.81944
157 3GGO ENO 0.01903 0.40179 4.14013
158 3GGO NAI 0.01903 0.40179 4.14013
159 2JJQ SAH 0.00006343 0.45512 4.16667
160 4FN4 NAD 0.0008156 0.44992 4.16667
161 5HSA FAS 0.001722 0.44907 4.16667
162 3H8V ATP 0.0002534 0.44843 4.16667
163 1ELI PYC 0.00151 0.44838 4.16667
164 2PX8 SAH 0.0002555 0.4475 4.16667
165 1J0X NAD 0.002758 0.4418 4.16667
166 3NTD FAD 0.002616 0.43771 4.16667
167 4REP FAD 0.002797 0.43748 4.16667
168 3OND ADN 0.006293 0.429 4.16667
169 3OND NAD 0.006293 0.429 4.16667
170 1RJD SAM 0.002141 0.41886 4.16667
171 3L4S NAD 0.005078 0.41797 4.16667
172 3L4S 3PG 0.005412 0.41797 4.16667
173 1PZG A3D 0.008391 0.41398 4.16667
174 1AE1 NAP 0.009005 0.40822 4.16667
175 1RKX NAD 0.01004 0.40376 4.16667
176 4J4H 1J1 0.02051 0.40205 4.16667
177 4J4H NAI 0.02139 0.40205 4.16667
178 4X9M FAD 0.001746 0.44775 4.30622
179 3A27 SAM 0.00001728 0.49307 4.58333
180 5JAQ NAI 0.0001984 0.48906 4.58333
181 4EUE NAI 0.0001648 0.48316 4.58333
182 1MO9 FAD 0.001863 0.4727 4.58333
183 1MO9 KPC 0.002974 0.46339 4.58333
184 4D7E FAD 0.0007471 0.45966 4.58333
185 3CGD NAD 0.005521 0.44923 4.58333
186 3CGD COA 0.005521 0.44923 4.58333
187 3CGD FAD 0.005521 0.44923 4.58333
188 3KLJ FAD 0.001216 0.44649 4.58333
189 2JB2 PHE 0.002298 0.44237 4.58333
190 2JB2 FAD 0.002176 0.44237 4.58333
191 2RGO FAD 0.002332 0.43883 4.58333
192 4OPC FDA 0.01522 0.43485 4.58333
193 4OPC PGT 0.01737 0.43485 4.58333
194 4USR FAD 0.002463 0.43302 4.58333
195 1O97 AMP 0.0096 0.4259 4.58333
196 1O97 FAD 0.0096 0.4259 4.58333
197 2E5V FAD 0.007483 0.42206 4.58333
198 5G3U FDA 0.006455 0.42013 4.58333
199 1ORR NAD 0.005039 0.41934 4.58333
200 4RSL FAD 0.006128 0.41901 4.58333
201 3VC1 SAH 0.007714 0.41865 4.58333
202 3VC1 GST 0.007714 0.41865 4.58333
203 3NGL NAP 0.002643 0.41504 4.58333
204 1DJN ADP 0.004952 0.40707 4.58333
205 1O94 ADP 0.005841 0.40563 4.58333
206 5G3U ITW 0.02091 0.4025 4.58333
207 2CUL FAD 0.00476 0.42277 4.74138
208 5HJM MTA 0.00004956 0.49203 5
209 3LAD FAD 0.0005015 0.47436 5
210 5KMS NAD 0.001027 0.47291 5
211 4XQC NAD 0.001474 0.45417 5
212 4XQC 13D 0.002392 0.44557 5
213 5KMS FAD 0.004647 0.42436 5
214 3VPH OXM 0.004841 0.42245 5
215 1P77 ATR 0.01883 0.41027 5
216 1BC5 SAH 0.004297 0.40967 5
217 5EOW FAD 0.009244 0.40886 5
218 3TKA SAM 0.01837 0.40592 5
219 1MXH NAP 0.01683 0.40142 5
220 3MJE NDP 0.01081 0.40112 5
221 2DC1 NAD 0.008418 0.40321 5.08475
222 4MIG G3F 0.001961 0.45319 5.09259
223 5N53 8NB 0.02446 0.40555 5.12821
224 1WY7 SAH 0.00002326 0.50305 5.31401
225 1XDS SAM 0.002148 0.43856 5.34759
226 4FZV SAM 0.00005438 0.48536 5.41667
227 3S1S SAH 0.0001678 0.46909 5.41667
228 4HA6 FAD 0.002661 0.4425 5.41667
229 2IID PHE 0.005128 0.43791 5.41667
230 2IID FAD 0.005128 0.43791 5.41667
231 4TM3 FAD 0.008287 0.43613 5.41667
232 4ITU NAI 0.002564 0.43224 5.41667
233 4ITU 1HS 0.004262 0.43224 5.41667
234 5O4J SAH 0.005704 0.41814 5.41667
235 5O4J 9KH 0.005704 0.41814 5.41667
236 5O4J PJL 0.005534 0.41754 5.41667
237 1C1X NAD 0.005245 0.41064 5.41667
238 2G5C NAD 0.008972 0.40464 5.41667
239 1BXG NAD 0.008171 0.40237 5.41667
240 4II2 ATP 0.004635 0.40485 5.52147
241 1U2Z SAH 0.000001207 0.55943 5.83333
242 2F5Z FAD 0.0002025 0.49332 5.83333
243 1ZMD FAD 0.0002233 0.49139 5.83333
244 3RNM FAD 0.0002569 0.48863 5.83333
245 2Z3Y F2N 0.001218 0.45792 5.83333
246 1ZMD NAI 0.0005371 0.45136 5.83333
247 2UYQ SAM 0.003181 0.45058 5.83333
248 4EMI NAD 0.004008 0.44658 5.83333
249 4EMI FAD 0.001657 0.44658 5.83333
250 2Q7V FAD 0.002147 0.44473 5.83333
251 4FWE FAD 0.003216 0.43876 5.83333
252 1JNR FAD 0.0134 0.42891 5.83333
253 4GKV NAD 0.004041 0.42476 5.83333
254 3CIF NAD 0.003347 0.4219 5.83333
255 3CIF G3H 0.008758 0.41101 5.83333
256 3TKY SAH 0.003746 0.40561 5.83333
257 3L9W AMP 0.00001632 0.52539 6.25
258 3SQP FAD 0.0007856 0.51834 6.25
259 4M73 SAH 0.00004432 0.51415 6.25
260 3PT9 SAH 0.000007286 0.50973 6.25
261 3L9W GSH 0.00003399 0.50806 6.25
262 4M73 M72 0.00006865 0.50709 6.25
263 3FUU ADN 0.00002389 0.49421 6.25
264 4UCI SAM 0.00009974 0.46921 6.25
265 1EFV FAD 0.002334 0.45542 6.25
266 1EFV AMP 0.002512 0.45393 6.25
267 5FJN BE2 0.00182 0.45193 6.25
268 5FJN FAD 0.001568 0.45193 6.25
269 1RSG FAD 0.002175 0.4455 6.25
270 1YY5 FAD 0.003685 0.43701 6.25
271 2VVM FAD 0.005325 0.42591 6.25
272 4J1Q NDP 0.0045 0.41494 6.25
273 1QZZ SAM 0.00793 0.41217 6.25
274 3Q9T FAY 0.01342 0.40485 6.25
275 2DFV NAD 0.008188 0.40373 6.25
276 1E1M NAP 0.002457 0.45202 6.52174
277 1E1M FAD 0.002457 0.45202 6.52174
278 1E6E FAD 0.001394 0.44761 6.52174
279 2XVM SAH 0.0001305 0.44418 6.53266
280 1EJ0 SAM 0.000005414 0.51414 6.66667
281 2VDV SAM 0.0002519 0.48178 6.66667
282 1XHC FAD 0.0006447 0.4625 6.66667
283 3X0D SAH 0.0002953 0.45019 6.66667
284 2B9W FAD 0.01221 0.421 6.66667
285 3LXD FAD 0.006692 0.4162 6.66667
286 4D42 NAP 0.01315 0.41581 6.66667
287 4D42 W0I 0.01315 0.41581 6.66667
288 2HJR APR 0.004846 0.40747 6.66667
289 2VHW NAI 0.0141 0.40286 6.66667
290 2VZ0 D64 0.04859 0.40257 6.66667
291 2VZ0 NAP 0.04859 0.40257 6.66667
292 3AD8 NAD 0.001447 0.44445 6.89655
293 3QFA FAD 0.003254 0.43756 6.89655
294 3AD8 PYC 0.01172 0.42771 6.89655
295 3AD8 FAD 0.01172 0.42771 6.89655
296 3JWH SAH 0.00001119 0.47423 6.91244
297 1Z3C SA8 0.00009996 0.48949 7.08333
298 1IM8 SAI 0.0001171 0.47148 7.08333
299 3BGD SAH 0.00049 0.44946 7.08333
300 4J36 FAD 0.001046 0.44937 7.08333
301 1Q9I FAD 0.003671 0.4462 7.08333
302 1Q9I TEO 0.003671 0.4462 7.08333
303 4J36 1HR 0.002246 0.44585 7.08333
304 3BGD PM6 0.0009419 0.44419 7.08333
305 3CTY FAD 0.002772 0.44265 7.08333
306 5XVK SAH 0.0008512 0.43935 7.08333
307 5EZ7 FAD 0.003195 0.43488 7.08333
308 4Z24 FAD 0.004282 0.43215 7.08333
309 3ETG GTP 0.02329 0.40035 7.08333
310 3Q87 SAM 0.0001104 0.47676 7.2
311 1D4D FAD 0.001332 0.45616 7.34266
312 3GRU AMP 0.00001249 0.51666 7.5
313 5L95 AMP 0.00008362 0.47224 7.5
314 1Y8Q ATP 0.0001037 0.45213 7.5
315 5EB4 FAD 0.001866 0.44749 7.5
316 4IV9 FAD 0.001894 0.44615 7.5
317 3IHG FAD 0.00125 0.4404 7.5
318 2ZWA SAH 0.001739 0.42449 7.5
319 3FRH SAH 0.003582 0.41301 7.5
320 1ZEM NAD 0.005557 0.40957 7.5
321 2AE2 NAP 0.01545 0.40499 7.5
322 2AE2 PTO 0.01545 0.40499 7.5
323 2HMT NAI 0.03534 0.41926 7.63889
324 3Q9N COA 0.006298 0.40723 7.80142
325 1UWK URO 0.00006656 0.51757 7.91667
326 1UWK NAD 0.00006656 0.51757 7.91667
327 4OBW SAM 0.00007282 0.48999 7.91667
328 2O07 SPD 0.0003034 0.46855 7.91667
329 2O07 MTA 0.0002557 0.46855 7.91667
330 2XVE FAD 0.004288 0.4452 7.91667
331 2XVF FAD 0.001978 0.44202 7.91667
332 1IY8 NAD 0.002166 0.43286 7.91667
333 1PS9 FAD 0.005746 0.4254 7.91667
334 3GDH SAH 0.0000001133 0.56512 8.33333
335 5THY SAH 0.00004755 0.48779 8.33333
336 1COY FAD 0.000928 0.46119 8.33333
337 4N49 SAM 0.0003397 0.4522 8.33333
338 2WA2 SAM 0.000162 0.4515 8.33333
339 5IL1 SAM 0.0005745 0.45103 8.33333
340 3NKS FAD 0.001251 0.45088 8.33333
341 1COY AND 0.003187 0.44909 8.33333
342 2V3A FAD 0.001899 0.44393 8.33333
343 2V3B FAD 0.001841 0.4434 8.33333
344 1YKJ PHB 0.005632 0.44096 8.33333
345 1YKJ FAD 0.005632 0.44096 8.33333
346 5JCA FAD 0.003402 0.43668 8.33333
347 5JCA NDP 0.007324 0.43489 8.33333
348 5K7U SAM 0.001103 0.42262 8.33333
349 1I1N SAH 0.00001205 0.52562 8.40708
350 2DPM SAM 0.00001972 0.50606 8.75
351 5E9W SAH 0.00003885 0.45364 8.75
352 1KNR FAD 0.003659 0.43326 8.75
353 1V8B NAD 0.006819 0.41694 8.75
354 2JHP SAH 0.003052 0.40227 8.75
355 1S7G APR 0.01381 0.40002 8.75
356 4YSX FAD 0.003174 0.43605 8.97436
357 3I53 SAH 0.002268 0.41781 9.03614
358 5E8J SAH 0.00005181 0.51367 9.09091
359 2GAG NAD 0.00174 0.4445 9.09091
360 2GAG FAD 0.009401 0.41929 9.09091
361 2GAG FOA 0.00986 0.41834 9.09091
362 3C6K MTA 0.0005026 0.4673 9.16667
363 3C6K SPD 0.0005026 0.4673 9.16667
364 4YRY FAD 0.00218 0.44545 9.16667
365 5FA5 MTA 0.000182 0.43958 9.16667
366 4YRY NAD 0.005609 0.43533 9.16667
367 4GQB 0XU 0.02844 0.42697 9.16667
368 4NBU NAI 0.006954 0.41074 9.2
369 1WG8 SAM 0.00002618 0.50522 9.58333
370 5GWX SAM 0.00005593 0.49512 9.58333
371 5GWX SAR 0.00005593 0.49512 9.58333
372 3S5W FAD 0.0003399 0.46793 9.58333
373 2YX1 SFG 0.00003888 0.46306 9.58333
374 2R4J 13P 0.003808 0.44237 9.58333
375 2R4J FAD 0.003808 0.44237 9.58333
376 5MZI FYK 0.005404 0.44046 9.58333
377 5MZI FAD 0.005223 0.44046 9.58333
378 3EGI ADP 0.0002468 0.50702 9.70874
379 5I39 FAD 0.0008812 0.45885 10
380 2A14 SAH 0.0004756 0.4481 10
381 1NVM NAD 0.003681 0.42534 10
382 1R18 SAH 0.002903 0.44446 10.1322
383 4EMJ FAD 0.002844 0.43715 10.2804
384 2HQM FAD 0.0003037 0.48423 10.4167
385 3E1T FAD 0.00247 0.44397 10.4167
386 4NTC FAD 0.002409 0.44248 10.4167
387 1H82 FAD 0.005216 0.43832 10.4167
388 1H82 GZZ 0.0062 0.43832 10.4167
389 3WLE NAD 0.01481 0.4019 10.4167
390 4QTU SAM 0.000005362 0.53312 10.5769
391 5THZ SAH 0.00002279 0.50564 10.8333
392 4JDR FAD 0.0002782 0.48482 10.8333
393 2XYQ SAH 0.00003556 0.48087 10.8333
394 2EJU SAH 0.00002007 0.49178 11.25
395 1NV8 SAM 0.0002357 0.47173 11.25
396 1NV8 MEQ 0.0002222 0.47118 11.25
397 3WGT FAD 0.0159 0.41042 11.25
398 3WGT QSC 0.01653 0.41042 11.25
399 4IWN GEK 0.00002514 0.50384 11.3537
400 3TLJ SAH 0.00001449 0.49384 11.6667
401 4RPL 3UC 0.001102 0.47736 12.0833
402 4RPL FAD 0.001195 0.47358 12.0833
403 3ICR FAD 0.0009217 0.45681 12.0833
404 3ICS FAD 0.001008 0.45625 12.0833
405 3ICT FAD 0.001854 0.44327 12.0833
406 2PXX SAH 0.0001474 0.46215 12.093
407 3VYW SAM 0.000001122 0.5556 12.5
408 1N4W FAD 0.002023 0.44791 12.5
409 3G5S FAD 0.005092 0.42368 12.5
410 3LCC SAH 0.0001921 0.45081 12.766
411 3WV8 ATP 0.0007693 0.43319 12.844
412 4Y2H SAH 0.00001187 0.54393 12.9167
413 4Y2H 49K 0.00001442 0.54013 12.9167
414 1NW5 SAM 0.0001516 0.4613 12.9167
415 4C3Y FAD 0.002232 0.44398 12.9167
416 4C3Y ANB 0.003132 0.44206 12.9167
417 3CMC NAD 0.04278 0.40063 12.9167
418 5M58 SAH 0.0001521 0.46184 13.0435
419 3VSE SAH 0.00009572 0.44138 13.3333
420 1KYZ SAH 0.001027 0.41609 13.3333
421 2WET FAD 0.01569 0.4056 13.3333
422 2PT9 2MH 0.0004681 0.46607 13.3956
423 2PT9 S4M 0.0002426 0.46607 13.3956
424 2EG5 SAH 0.00003999 0.51889 13.75
425 5MPT SAH 0.0000191 0.49249 13.75
426 3GU3 SAH 0.000006523 0.47669 13.75
427 1FEC FAD 0.002026 0.45073 13.75
428 5MGZ SAH 0.0001086 0.46793 13.9831
429 5X62 SAH 0.000007808 0.53835 14.1667
430 1I8T FAD 0.001134 0.45509 14.1667
431 4D04 NAP 0.005806 0.44033 14.1667
432 4D04 FAD 0.005806 0.44033 14.1667
433 4X7Y SAH 0.00002711 0.53048 14.5833
434 4AZW SAM 0.0001636 0.46074 14.5833
435 4DCM SAM 0.0001746 0.44276 14.5833
436 4ZCC NAI 0.003865 0.44127 14.5833
437 4ZCC FAD 0.003865 0.44127 14.5833
438 3OFK SAH 0.0003227 0.44659 14.8148
439 3SSO SAH 0.000008367 0.55215 15
440 4DMG SAM 0.00004888 0.52126 15
441 4CNK FAD 0.002959 0.43531 15.4167
442 3ML1 MGD 0.01539 0.42436 15.5556
443 2YVJ FAD 0.002027 0.44154 15.5963
444 2WPF WPF 0.002886 0.47118 15.8333
445 3G2O SAM 0.00007648 0.47077 15.8333
446 2WPF FAD 0.002997 0.46894 15.8333
447 1BXK NAD 0.003838 0.41933 15.8333
448 1JQ3 AAT 0.0002863 0.47409 16.25
449 1YQZ FAD 0.001245 0.46976 16.25
450 5D4V SAH 0.001613 0.42585 16.6667
451 4POO SAM 0.0007203 0.4442 17
452 5TTJ FAD 0.003062 0.43571 17.5
453 3UCL FAD 0.01464 0.42249 17.5
454 3UCL CYH 0.01464 0.42249 17.5
455 3UCL NAP 0.01594 0.42249 17.5
456 1VE3 SAM 0.0004136 0.45723 17.6211
457 5DLY 5D7 0.002277 0.44149 17.9167
458 5DLY SAH 0.002032 0.44149 17.9167
459 5U8U FAD 0.001071 0.47655 18.3333
460 5BUK FAD 0.003092 0.44049 18.3333
461 4HSU FAD 0.003035 0.44085 18.5484
462 4GUT FAD 0.003716 0.43866 18.5484
463 1KK8 BEF ADP 0.007361 0.40627 18.705
464 1TPY SAH 0.0005812 0.44445 19.1667
465 1ZQ9 SAM 0.000004462 0.51577 19.5833
466 3G89 SAM 0.000005585 0.49404 20.0803
467 1JG3 ADN 0.00001332 0.49753 20.4255
468 1DL5 SAH 0.000000528 0.58181 20.8333
469 2NXE SAM 0.00007583 0.46833 21.25
470 3EGV SAH 0.0004286 0.46115 21.25
471 3OID NDP 0.01072 0.40487 22.0833
472 5DX0 SFG 0.000008673 0.52771 25
473 5DX8 SFG 0.000009349 0.52196 25
474 5DX1 SFG 0.00001191 0.52184 25
475 5DWQ SFG 0.00001462 0.51595 25
476 5DXA SFG 0.0000117 0.49591 25
477 4C4A SAH 0.00003106 0.48998 26.6667
478 3DUW SAH 0.0000000000005785 0.80273 29.5964
479 3NDJ JHZ 0.01163 0.41588 30
480 3NDJ SAH 0.01163 0.41588 30
481 1LSS NAD 0.00001644 0.50701 30.7143
482 4XUC 43G 0.0000000001963 0.74728 32.5688
483 4XUC SAM 0.0000000001963 0.74728 32.5688
484 3C3Y SAH 0.0000000001471 0.70599 37.1308
485 3HVJ 705 0.0000000003514 0.74289 38.009
486 3CBG SAH 0.00001395 0.54078 39.2241
Pocket No.: 2; Query (leader) PDB : 4YMH; Ligand: SAH; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4ymh.bio2) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4YMH; Ligand: SAH; Similar sites found: 14
This union binding pocket(no: 3) in the query (biounit: 4ymh.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2VGD XYP XYP 0.02193 0.40637 1.83486
2 3R75 PYR 0.008412 0.43202 2.91667
3 1XG5 NAP 0.007092 0.40448 3.33333
4 3H4V DVP 0.01369 0.40379 3.75
5 3MB5 SAM 0.02906 0.42018 4.58333
6 3AFN NAP 0.005346 0.41212 5
7 1MXH DHF 0.01118 0.40384 5
8 2B4Q NAP 0.007985 0.40105 5.41667
9 5WSY 7UC 0.0146 0.41473 5.78035
10 2EXX NAP 0.009557 0.40255 7.08333
11 2CFC NAD 0.007347 0.40126 7.08333
12 4ZA2 NAD 0.006551 0.40334 7.5
13 1BZL FAD 0.004093 0.45645 12.0833
14 1Z6Z NAP 0.005696 0.4072 12.5
Pocket No.: 4; Query (leader) PDB : 4YMH; Ligand: SAH; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4ymh.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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