-->
Receptor
PDB id Resolution Class Description Source Keywords
4XVU 2.35 Å EC: 3.6.-.- STRUCTURE OF GET3 BOUND TO THE TRANSMEMBRANE DOMAIN OF NYV1 SACCHAROMYCES CEREVISIAE (ATCC 204508 ORGANISM_COMMON: BAKER-prime S YEAST MEMBRANE PROTEIN TARGETING COMPLEX HYDROLASE-TRANSPORT PROTCOMPLEX
Ref.: PROTEIN TARGETING. STRUCTURE OF THE GET3 TARGETING COMPLEX WITH ITS MEMBRANE PROTEIN CARGO. SCIENCE V. 347 1152 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ATP A:401;
B:401;
G:401;
H:401;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
MG A:402;
B:402;
G:402;
H:402;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
ZN A:403;
G:403;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XVU 2.35 Å EC: 3.6.-.- STRUCTURE OF GET3 BOUND TO THE TRANSMEMBRANE DOMAIN OF NYV1 SACCHAROMYCES CEREVISIAE (ATCC 204508 ORGANISM_COMMON: BAKER-prime S YEAST MEMBRANE PROTEIN TARGETING COMPLEX HYDROLASE-TRANSPORT PROTCOMPLEX
Ref.: PROTEIN TARGETING. STRUCTURE OF THE GET3 TARGETING COMPLEX WITH ITS MEMBRANE PROTEIN CARGO. SCIENCE V. 347 1152 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4XVU - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4XVU - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3GJF Kd = 46 nM SER LEU LEU MET TRP ILE THR GLN VAL n/a n/a
2 2ZPK - PRO ARG GLY TYR PRO GLY GLN VAL n/a n/a
3 3NIF - NIF C11 H15 N5 O S CCC1=NN2C(....
4 3ZDY - GLY ARG GLY ASP SER PRO n/a n/a
5 3ZE2 - GLY ARG GLY ASP SER PRO n/a n/a
6 2VDR - LEU GLY GLY ALA LYS GLN ARG GLY ASP VAL n/a n/a
7 3WFD - AXO C2 H5 N O C/C=N/O
8 4XVU - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
9 4XTR - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
10 1W72 Kd = 14 nM GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
11 5X2N - ALA C3 H7 N O2 C[C@@H](C(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 422
No: Ligand ECFP6 Tc MDL keys Tc
1 HEJ 1 1
2 ATP 1 1
3 5FA 0.985507 1
4 AQP 0.985507 1
5 AP5 0.927536 0.971831
6 B4P 0.927536 0.971831
7 BA3 0.913043 0.971831
8 ADP 0.9 1
9 A2D 0.884058 0.971831
10 AGS 0.84 0.945946
11 SAP 0.84 0.945946
12 6YZ 0.833333 0.972222
13 AT4 0.810811 0.958904
14 AN2 0.810811 0.985915
15 25L 0.809524 0.985915
16 AR6 0.802632 0.971831
17 APR 0.802632 0.971831
18 M33 0.8 0.958333
19 ACQ 0.794872 0.972222
20 TAT 0.794872 0.958904
21 T99 0.794872 0.958904
22 AD9 0.792208 0.972222
23 ACP 0.789474 0.972222
24 AMP 0.788732 0.971429
25 A 0.788732 0.971429
26 ANP 0.772152 0.972222
27 CA0 0.753247 0.945205
28 ADX 0.753247 0.873418
29 A22 0.746988 0.985915
30 50T 0.74359 0.958333
31 PRX 0.734177 0.893333
32 APC 0.734177 0.958904
33 ABM 0.733333 0.917808
34 ATF 0.731707 0.958904
35 ITT 0.730769 0.943662
36 7D4 0.730769 0.905405
37 ADQ 0.729412 0.945205
38 A3R 0.729412 0.907895
39 AP2 0.714286 0.958904
40 A12 0.714286 0.958904
41 A1R 0.709302 0.907895
42 SRA 0.706667 0.918919
43 5AL 0.698795 0.931507
44 HFD 0.695122 0.945946
45 9X8 0.693182 0.92
46 OAD 0.693182 0.945205
47 AU1 0.6875 0.972222
48 SRP 0.682353 0.906667
49 G5P 0.680851 0.921053
50 25A 0.678161 0.971831
51 3OD 0.677778 0.945205
52 4AD 0.670455 0.92
53 G3A 0.670213 0.921053
54 00A 0.662921 0.883117
55 RBY 0.662651 0.932432
56 ADP PO3 0.662651 0.943662
57 ADV 0.662651 0.932432
58 BIS 0.659341 0.933333
59 8QN 0.659091 0.931507
60 5SV 0.659091 0.848101
61 OOB 0.659091 0.931507
62 GTA 0.65625 0.886076
63 UP5 0.653061 0.92
64 AMO 0.651685 0.932432
65 PAJ 0.651685 0.884615
66 2A5 0.650602 0.918919
67 MAP 0.647727 0.945946
68 3AT 0.647059 0.971831
69 AHX 0.644444 0.896104
70 DLL 0.644444 0.931507
71 ATR 0.642857 0.971429
72 PAP 0.642857 0.985714
73 PTJ 0.641304 0.896104
74 7D3 0.6375 0.905405
75 3UK 0.637363 0.918919
76 SON 0.634146 0.932432
77 A4P 0.633663 0.843373
78 ALF ADP 0.632184 0.87013
79 ADP ALF 0.632184 0.87013
80 PR8 0.630435 0.85
81 WAQ 0.630435 0.883117
82 LAD 0.630435 0.860759
83 B5V 0.630435 0.906667
84 AFH 0.628866 0.884615
85 LMS 0.628205 0.82716
86 GAP 0.627907 0.893333
87 DTP 0.627907 0.905405
88 VO4 ADP 0.625 0.931507
89 ADP VO4 0.625 0.931507
90 TXA 0.623656 0.932432
91 ME8 0.623656 0.839506
92 1ZZ 0.623656 0.839506
93 NB8 0.623656 0.896104
94 FYA 0.623656 0.905405
95 DQV 0.622449 0.958333
96 T5A 0.621359 0.841463
97 ADN 0.619718 0.84507
98 RAB 0.619718 0.84507
99 XYA 0.619718 0.84507
100 DAL AMP 0.611111 0.905405
101 9SN 0.610526 0.871795
102 48N 0.61 0.896104
103 AP0 0.607843 0.896104
104 9ZD 0.604396 0.907895
105 9ZA 0.604396 0.907895
106 FA5 0.604167 0.906667
107 B5M 0.604167 0.894737
108 YAP 0.604167 0.894737
109 B5Y 0.604167 0.894737
110 NAI 0.60396 0.907895
111 6V0 0.60396 0.896104
112 TXD 0.60396 0.907895
113 DND 0.60396 0.932432
114 NXX 0.60396 0.932432
115 NAX 0.60396 0.873418
116 ADP BMA 0.602151 0.918919
117 A2R 0.6 0.985915
118 OMR 0.598039 0.851852
119 TXE 0.598039 0.907895
120 XAH 0.597938 0.839506
121 7DT 0.593023 0.985714
122 AOC 0.592593 0.821918
123 4UV 0.591837 0.894737
124 DDS 0.590909 0.878378
125 139 0.590476 0.873418
126 CNA 0.584906 0.932432
127 6AD 0.58427 0.909091
128 5AS 0.583333 0.77907
129 5N5 0.581081 0.819444
130 GA7 0.58 0.906667
131 4UU 0.58 0.894737
132 4TC 0.576923 0.896104
133 ADJ 0.575472 0.851852
134 5CD 0.573333 0.805556
135 A4D 0.573333 0.819444
136 RGT 0.571429 0.958904
137 A3P 0.571429 0.971429
138 7D5 0.56962 0.878378
139 LAQ 0.568627 0.839506
140 F2R 0.564815 0.864198
141 80F 0.563636 0.841463
142 YLP 0.563107 0.819277
143 A A 0.5625 0.944444
144 UPA 0.561905 0.907895
145 AV2 0.56044 0.917808
146 COD 0.559633 0.811765
147 4UW 0.557692 0.860759
148 JB6 0.556701 0.883117
149 3AM 0.555556 0.929577
150 ATP A A A 0.555556 0.930556
151 A2P 0.552941 0.957143
152 TYM 0.552381 0.906667
153 NA7 0.552083 0.958904
154 EP4 0.551282 0.753247
155 MYR AMP 0.55102 0.817073
156 PPS 0.549451 0.873418
157 YLC 0.54717 0.839506
158 YLB 0.54717 0.819277
159 NAD 0.545455 0.931507
160 DAT 0.545455 0.905405
161 TYR AMP 0.544554 0.87013
162 G5A 0.544444 0.77907
163 M2T 0.544304 0.734177
164 DTA 0.544304 0.786667
165 3DH 0.54321 0.773333
166 128 0.542857 0.776471
167 AHZ 0.538462 0.817073
168 GTP 0.537634 0.92
169 SSA 0.537634 0.8
170 MTA 0.5375 0.773333
171 IOT 0.537037 0.831325
172 A3D 0.535714 0.918919
173 ARG AMP 0.533981 0.829268
174 7MD 0.533981 0.8625
175 AR6 AR6 0.533981 0.917808
176 YLA 0.53211 0.819277
177 AMP DBH 0.529412 0.893333
178 IMO 0.529412 0.929577
179 TAD 0.528846 0.884615
180 AYB 0.527273 0.809524
181 A5A 0.526882 0.807229
182 HDV 0.526882 0.893333
183 TSB 0.526316 0.819277
184 EAD 0.525424 0.873418
185 2AM 0.52439 0.943662
186 6RE 0.52381 0.759494
187 7DD 0.522727 0.985714
188 V3L 0.521739 0.971831
189 AVV 0.520833 0.896104
190 BTX 0.517857 0.841463
191 NAE 0.517241 0.894737
192 52H 0.515789 0.77907
193 54H 0.515789 0.788235
194 VMS 0.515789 0.788235
195 NSS 0.515464 0.8
196 BT5 0.513274 0.831325
197 NAQ 0.512821 0.871795
198 ZAS 0.511905 0.766234
199 J7C 0.511628 0.769231
200 A3N 0.511628 0.786667
201 5X8 0.511111 0.763158
202 53H 0.510417 0.77907
203 8X1 0.510417 0.752809
204 5CA 0.510417 0.8
205 NVA LMS 0.510204 0.752809
206 ARU 0.510204 0.860759
207 AF3 ADP 3PG 0.509259 0.8375
208 ZID 0.508475 0.918919
209 P1H 0.508197 0.851852
210 OVE 0.505882 0.905405
211 S4M 0.505747 0.666667
212 LEU LMS 0.50505 0.752809
213 LPA AMP 0.504673 0.817073
214 7MC 0.504587 0.841463
215 DZD 0.5 0.884615
216 FB0 0.5 0.804598
217 MAO 0.5 0.759036
218 DSZ 0.5 0.8
219 LSS 0.5 0.761364
220 DSH 0.5 0.725
221 P5A 0.5 0.744444
222 NDE 0.495935 0.932432
223 N0B 0.495798 0.819277
224 M24 0.495726 0.85
225 YLY 0.495726 0.809524
226 NJP 0.495575 0.945946
227 9K8 0.49505 0.714286
228 MGP 0.494737 0.884615
229 6C6 0.494624 0.881579
230 NAJ PZO 0.491379 0.848101
231 0WD 0.491228 0.921053
232 6G0 0.489583 0.884615
233 GJV 0.488636 0.75
234 6FA 0.488189 0.841463
235 5AD 0.486842 0.746479
236 KAA 0.485149 0.752809
237 GSU 0.485149 0.77907
238 71V 0.483146 0.907895
239 NEC 0.482759 0.746667
240 A3G 0.482759 0.8
241 ODP 0.482456 0.909091
242 FAS 0.48062 0.851852
243 FAD 0.48062 0.851852
244 7D7 0.480519 0.743243
245 FDA 0.480315 0.833333
246 N6P 0.48 0.915493
247 2SA 0.479167 0.932432
248 GP3 0.478723 0.921053
249 4TA 0.478261 0.807229
250 SFG 0.478261 0.75
251 G A A A 0.478261 0.871795
252 AMP NAD 0.478261 0.905405
253 NPW 0.477876 0.886076
254 NDP 0.477876 0.921053
255 NDC 0.47619 0.871795
256 YSA 0.47619 0.77907
257 NAJ PYZ 0.475 0.807229
258 MGO 0.474227 0.860759
259 GDP 0.473684 0.92
260 NZQ 0.473684 0.909091
261 TXP 0.473684 0.921053
262 6IA 0.473684 0.8375
263 A7D 0.472527 0.776316
264 SFD 0.469231 0.734043
265 A5D 0.468085 0.786667
266 SA8 0.468085 0.707317
267 ZDA 0.468085 0.864865
268 12D 0.46789 0.785714
269 PGS 0.467391 0.883117
270 MHZ 0.467391 0.697674
271 8PZ 0.466667 0.8
272 62F 0.466165 0.8625
273 DA 0.465909 0.878378
274 D5M 0.465909 0.878378
275 GGZ 0.464646 0.825
276 SAH 0.463158 0.74359
277 SAI 0.463158 0.734177
278 FAY 0.462687 0.8625
279 Y3J 0.4625 0.726027
280 PO4 PO4 A A A A PO4 0.460784 0.902778
281 AAM 0.460674 0.971429
282 RFL 0.459259 0.821429
283 SMM 0.459184 0.686047
284 HF7 0.459184 0.893333
285 AMZ 0.458824 0.916667
286 C2R 0.458824 0.90411
287 SAM 0.458333 0.690476
288 A3S 0.456522 0.810811
289 FNK 0.455224 0.804598
290 U A 0.453782 0.907895
291 7C5 0.453704 0.818182
292 EEM 0.453608 0.690476
293 AAT 0.453608 0.707317
294 XNP 0.452991 0.873418
295 A G 0.452991 0.883117
296 PRT 0.45283 0.931507
297 AIR 0.451219 0.901408
298 62X 0.45098 0.666667
299 DCA 0.45 0.823529
300 ETB 0.45 0.833333
301 GSP 0.45 0.873418
302 U A G G 0.449153 0.883117
303 NIA 0.448276 0.822785
304 A3T 0.446809 0.821918
305 A A A 0.446602 0.905405
306 K15 0.446602 0.682353
307 PUA 0.446281 0.884615
308 6K6 0.445545 0.930556
309 GEK 0.445545 0.7375
310 4YB 0.445455 0.761364
311 S7M 0.444444 0.690476
312 Z5A 0.443548 0.77907
313 1DG 0.443548 0.921053
314 DG1 0.443548 0.921053
315 0T1 0.442623 0.823529
316 COA 0.442623 0.823529
317 WSA 0.442478 0.788235
318 8BR 0.43956 0.906667
319 8Q2 0.438596 0.772727
320 101 0.438202 0.878378
321 IDP 0.4375 0.918919
322 NVA 2AD 0.4375 0.759494
323 9JJ 0.435714 0.8625
324 NAP 0.435484 0.945205
325 APU 0.434783 0.894737
326 A U 0.434783 0.87013
327 7RP 0.433333 0.928571
328 A6D 0.432692 0.722892
329 AMX 0.432 0.833333
330 J7V 0.432 0.833333
331 TAP 0.432 0.907895
332 COS 0.432 0.804598
333 CAO 0.432 0.795455
334 30N 0.432 0.752688
335 V1N 0.431193 0.917808
336 649 0.429825 0.744444
337 P5F 0.429577 0.823529
338 NA0 0.428571 0.932432
339 SCO 0.428571 0.823529
340 CMX 0.428571 0.823529
341 7RA 0.428571 0.957747
342 0UM 0.427184 0.698795
343 GAV 0.427184 0.884615
344 QQY 0.426966 0.815789
345 1RB 0.426966 0.885714
346 ACK 0.426966 0.861111
347 G1R 0.425743 0.907895
348 GCP 0.425743 0.896104
349 FAM 0.425197 0.804598
350 FCX 0.425197 0.795455
351 ACO 0.425197 0.795455
352 GNH 0.424242 0.907895
353 F2N 0.423611 0.813953
354 GKE 0.422018 0.884615
355 GDD 0.422018 0.884615
356 GDC 0.422018 0.884615
357 HAX 0.421875 0.804598
358 3AD 0.421687 0.805556
359 9GM 0.421569 0.896104
360 GNP 0.421569 0.896104
361 FA9 0.42069 0.864198
362 TM1 0.420561 0.77381
363 KB1 0.420561 0.698795
364 H6Y 0.42 0.945205
365 2MC 0.419847 0.769231
366 3KK 0.418605 0.804598
367 FYN 0.418605 0.823529
368 S8M 0.417476 0.759494
369 7L1 0.417323 0.795455
370 2VA 0.416667 0.8
371 26A 0.416667 0.763158
372 NHD 0.416667 0.905405
373 QQX 0.41573 0.805195
374 CA6 0.415385 0.729167
375 OXK 0.415385 0.804598
376 COK 0.415385 0.804598
377 SOP 0.415385 0.804598
378 MCD 0.415385 0.804598
379 YE1 0.413534 0.813953
380 RMB 0.413043 0.873239
381 FAI 0.413043 0.916667
382 AS 0.413043 0.833333
383 CO6 0.412214 0.804598
384 1VU 0.412214 0.795455
385 CMC 0.412214 0.804598
386 NMX 0.412214 0.76087
387 SXZ 0.411215 0.710843
388 ANZ 0.410714 0.8
389 SCA 0.410448 0.804598
390 CAJ 0.409091 0.804598
391 SCD 0.409091 0.823529
392 EO7 0.408602 0.788235
393 D3Y 0.407767 0.789474
394 CC5 0.407407 0.816901
395 KH3 0.40708 0.674419
396 A C A C 0.406504 0.848101
397 SLU 0.406504 0.770115
398 G 0.40625 0.906667
399 5GP 0.40625 0.906667
400 A1S 0.406015 0.804598
401 IVC 0.406015 0.813953
402 MLC 0.406015 0.804598
403 3HC 0.406015 0.813953
404 1HE 0.406015 0.786517
405 BCO 0.406015 0.804598
406 GTG 0.405405 0.886076
407 NMN AMP PO4 0.404959 0.87013
408 3D1 0.404762 0.773333
409 3L1 0.404762 0.773333
410 2BA 0.404255 0.915493
411 CMP 0.404255 0.901408
412 VRT 0.40404 0.769231
413 SO8 0.40404 0.789474
414 MCA 0.402985 0.795455
415 COO 0.402985 0.804598
416 CAA 0.402985 0.813953
417 3NZ 0.401869 0.782051
418 G2R 0.401869 0.884615
419 ZZB 0.4 0.77381
420 2FA 0.4 0.813333
421 MC4 0.4 0.76087
422 2CP 0.4 0.795455
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4XVU; Ligand: ATP; Similar sites found with APoc: 691
This union binding pocket(no: 1) in the query (biounit: 4xvu.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3LRE ADP 2.82486
2 4KFU ACP 2.83019
3 4R2I ANP 2.85714
4 3DC4 ADP 3.04348
5 4RD0 GDP 3.04348
6 3CNL GNP 3.05344
7 3H86 AP5 3.125
8 3BER AMP 3.21285
9 5O2J 2PO 3.2967
10 6BCA GSP 3.31126
11 2JK0 ASP 3.38462
12 5JCP GDP ALF 3.38983
13 1T5C ADP 3.47826
14 4D0N GDP 3.47826
15 3PQC GDP 3.58974
16 4JLV ADP 3.68664
17 3U6B GDP 3.68664
18 5JBQ GDP 3.68664
19 4G5G GDP 3.68664
20 1D8T GDP 3.68664
21 3U6K GDP 3.68664
22 2BVN GNP 3.68664
23 4LYA ATP 3.68664
24 6AU6 GDP 3.68664
25 4NE2 SH2 3.68664
26 4NE2 ADP 3.68664
27 2Z5F A3P 3.68664
28 1ZIN AP5 3.68664
29 1QHG ATP 3.68664
30 4DKX GDP 3.7037
31 1G3M A3P 3.7415
32 1G3M PCQ 3.7415
33 3RWO GDP 3.78378
34 2Y8E GNP 3.91061
35 2RCN GDP 3.91304
36 1SQ5 ADP 3.91304
37 2CE7 ADP 3.91304
38 1AQU A3P 3.91304
39 4DDY DN6 3.91304
40 3BOS CDP 3.91304
41 6FAA ADP 3.91304
42 4U5X GNP 3.93258
43 3IUY AMP 3.94737
44 1W5T ADP 3.9548
45 1W5T ANP 3.9548
46 4M9Q GNP 3.96476
47 2HF9 GSP 3.9823
48 1F6B GDP 4.0404
49 2XT3 ADP 4.14747
50 5H7J GCP 4.14747
51 5H7K GDP 4.14747
52 1DAK ADP 4.14747
53 1DAK DPU 4.14747
54 4QOS ADP 4.15094
55 5KSP GDP 4.21053
56 5Y6N ADP 4.23729
57 2ZJ5 ADP 4.23729
58 2FNA ADP 4.23729
59 2ZJ1 NAD 4.23729
60 2ZJ1 ARJ 4.23729
61 1M7G AV2 4.2654
62 1M7G ADX 4.2654
63 1M7G ADP 4.2654
64 2VVG ADP 4.28571
65 2BME GNP 4.30108
66 1D5C GDP 4.32099
67 1VG8 GNP 4.34783
68 1G7S GDP 4.34783
69 1Y63 ADP 4.34783
70 4ZG4 VO4 ADP 4.34783
71 4B5W PYR 4.34783
72 3VX3 ADP 4.51977
73 2JLR ANP 4.51977
74 2GWH A3P 4.51977
75 5G41 AP5 4.60829
76 3QVV 3QV 4.60829
77 3QVV A3P 4.60829
78 5JVB 2PO 4.60829
79 1PUJ GNP 4.60993
80 2FFQ GSP 4.67836
81 2XTN GTP 4.70085
82 1YZQ GNP 4.70588
83 2A5J GDP 4.71204
84 3KC1 2T6 4.74777
85 2FAH GDP 4.78261
86 3L6C MLI 4.78261
87 4NU0 AP5 4.78261
88 5M04 GDP 4.80226
89 4AG5 ADP 4.80226
90 2WHX ADP 4.80226
91 2VPQ ANP 4.80226
92 3SBD GNP 4.81283
93 3Q72 GNP 4.81928
94 6B8B ADP 4.81928
95 1MH1 GNP 4.83871
96 1VG1 GDP 4.86486
97 1GWN GTP 4.87805
98 1G4U GDP 4.8913
99 1Y7P RIP 4.93274
100 4LPS GDP 4.95868
101 3SFV GDP 4.97238
102 5O74 GDP 5
103 1O8B ABF 5.02283
104 3KJI ADP 5.06912
105 3GJ0 GDP 5.06912
106 1RRC ADP 5.06912
107 3GJ4 GDP 5.06912
108 5UWQ GNP 5.06912
109 5UWS GNP 5.06912
110 5UWU GNP 5.06912
111 1XP8 AGS 5.06912
112 2ZTS ADP 5.06912
113 5UWR GNP 5.06912
114 5UWT GNP 5.06912
115 5DIF GNP 5.06912
116 5UWJ GNP 5.06912
117 5DHF GNP 5.06912
118 5UWW GNP 5.06912
119 5UWP GNP 5.06912
120 5DI9 GNP 5.06912
121 5EXT ADP 5.06912
122 1AKY AP5 5.06912
123 1NST A3P 5.06912
124 2QZ4 ADP 5.06912
125 3MGB PAP 5.06912
126 6CS8 F9Y 5.08475
127 4HAT GNP 5.09259
128 3FB4 AP5 5.09259
129 6G14 G4P 5.10204
130 3NKV GNP 5.14286
131 1D2N ANP 5.14706
132 1QF9 C5P 5.15464
133 1QF9 ALF 5.15464
134 1QF9 ADP 5.15464
135 1YRB GDP 5.21739
136 3WY9 GDP 5.21739
137 3WYA GDP 5.21739
138 2IYL GDP 5.21739
139 2OBM ADP 5.21739
140 4OHY ANP 5.21739
141 2I4I AMP 5.21739
142 5EDE 5M6 5.21739
143 5WDR GNP 5.26316
144 4QM7 GTP 5.26316
145 5VHC BEF ADP 5.28736
146 4K7O EKZ 5.35714
147 2GK6 ADP 5.36723
148 4NON GDP 5.38462
149 1KAO GDP 5.38922
150 1M7B GTP 5.43478
151 3M1I GTP 5.47945
152 5ZXD ATP 5.52995
153 3FKQ ATP 5.52995
154 5L3V GDP 5.52995
155 4PX9 ADP 5.52995
156 1TAD ALF 5.52995
157 1TAD GDP 5.52995
158 2XTZ GSP 5.52995
159 4D81 ADP 5.52995
160 2O0J ADP 5.52995
161 5VZ0 ADP 5.52995
162 1YZG GDP 5.58659
163 3EWA ANP 5.59006
164 3FYH ADP 5.59006
165 5J1J ANP 5.64972
166 4RZ3 ADP 5.64972
167 2DPY ADP 5.64972
168 1JI0 ATP 5.64972
169 6F3N ADN 5.64972
170 4PVR ASP 5.64972
171 3EZ2 ADP 5.65217
172 4LC1 GDP 5.65217
173 1G41 ADP 5.65217
174 4ZKD GDP 5.65217
175 2J0V GDP 5.66038
176 4YDS ATP 5.70175
177 2YOH WMJ 5.71429
178 1JJ7 ADP 5.76923
179 2OFW ADX 5.76923
180 1EK0 GNP 5.88235
181 2RGX AP5 5.9322
182 1NHX FTB 5.9322
183 1NHX PEP 5.9322
184 2GMV UN8 5.9322
185 3X1Z GNP 5.98802
186 2OG2 MLI 5.99078
187 5FTB ANP 5.99078
188 1B7T ADP 5.99078
189 3B7G ANP 5.99078
190 3TKL GTP 5.99078
191 1KK8 BEF ADP 5.99078
192 3HU3 AGS 5.99078
193 1LVK MNT BEF 5.99078
194 2IXE ATP 5.99078
195 1S3G AP5 5.99078
196 4P4T GDP 5.99078
197 5BYK A3P 5.99078
198 5BYK OAQ 5.99078
199 3R7F CP 5.99078
200 5E58 CPZ 5.99078
201 2F9L GDP 6.03015
202 2WIC GNP 6.08696
203 4IHQ ADP 6.08696
204 5IFS ADP 6.08696
205 6ACS CIT 6.08696
206 1B0U ATP 6.10687
207 4FCW ADP 6.10932
208 3BC1 GNP 6.15385
209 2X7I CIT 6.16883
210 5MVR ADP 6.17284
211 3MD0 GDP 6.21469
212 1W7J ADP BEF 6.21469
213 1GQY ACP 6.21469
214 1OIX GDP 6.28272
215 1OIV GDP 6.28272
216 1JJV ATP 6.31068
217 3KTA AP5 6.35838
218 1G6O ADP 6.36364
219 2GJ8 ALF GDP 6.39535
220 1XEX ATP 6.39535
221 5VJN IR8 6.41711
222 5W7Q GDP 6.45161
223 1G6H ADP 6.45161
224 4MKG AP5 6.45161
225 4KVA GTP 6.45161
226 6DEF GCP 6.45161
227 2EW1 GNP 6.46766
228 4TTQ ATP 6.51163
229 5CK5 GDP 6.52174
230 3NHB ADP 6.52174
231 4R98 GNH 6.52174
232 2C77 GNP 6.52174
233 4ZNL BEF ADP 6.52174
234 2C78 GNP 6.52174
235 4A4Z ANP 6.52174
236 1U0J ADP 6.52174
237 1SVM ATP 6.52174
238 5M67 3D1 6.52174
239 5M67 NAD 6.52174
240 5M67 ADE 6.52174
241 1P72 ADP 6.52174
242 4BAS GNP 6.53266
243 5SZH GNP 6.53595
244 5EP2 AZU 6.64062
245 3DOE GTP 6.66667
246 5JCZ GDP 6.70391
247 2PEZ DAT 6.70391
248 2PEZ GGZ 6.70391
249 1FP6 ADP 6.77966
250 3COB ADP 6.77966
251 1S8F GDP 6.77966
252 4LX0 BEF GDP 6.77966
253 1D2E GDP 6.77966
254 2BCG GDP 6.79612
255 2GDJ ANP 6.81818
256 5UQW GDP 6.87831
257 2GKS ADP 6.91244
258 3AB3 GDP 6.91244
259 1ZCB GDP 6.91244
260 3FVQ ATP 6.91244
261 2BIF ANP 6.91244
262 2BIF SIN 6.91244
263 4C4P GNP 6.93642
264 3B9Q MLI 6.95364
265 3Q9L ATP 6.95652
266 5I34 GDP 6.95652
267 1NJF ADP 6.95652
268 1NJF AGS 6.95652
269 4IOK ADP 6.95652
270 5MEX PAP 6.95652
271 4IOK XPO 6.95652
272 4QDI ATP 6.95652
273 5MEX SZZ 6.95652
274 3RC3 ANP 6.95652
275 1NRJ GTP 6.96203
276 1NY5 ADP 6.97674
277 2FH5 GTP 7.02703
278 2FSH ANP 7.06215
279 2J5V PCA 7.06215
280 2Q2Y MKR 7.06215
281 2Q2Y ADP 7.06215
282 5Z69 AGS 7.06215
283 1LVG ADP 7.07071
284 2QEN ADP 7.14286
285 1ZUI SKM 7.14286
286 3BD9 A3P 7.14286
287 1Z83 AP5 7.14286
288 2D7C GTP 7.18563
289 3IIJ ADP 7.22222
290 1OW3 GDP 7.25389
291 1DS6 GDP 7.29167
292 1RJ9 GCP 7.34463
293 4X8O AP5 7.34463
294 1SVK ALF GDP 7.36544
295 5GVR LMR 7.37327
296 4HSE ADP 7.37327
297 3QXC ATP 7.37327
298 5H4S RAM 7.37327
299 1GOJ ADP 7.3913
300 5MZN ADP 7.3913
301 1CR1 TTP 7.3913
302 2WKQ GTP 7.3913
303 2ZPA ADP 7.3913
304 2BHZ MAL 7.3913
305 1UJ2 ADP 7.3913
306 1UJ2 C5P 7.3913
307 4V03 ADP 7.393
308 1ION ADP 7.40741
309 5KUT GDP 7.40741
310 3ZFD ANP 7.40741
311 1ZD9 GDP 7.44681
312 1Z0A GDP 7.47126
313 2A9K GDP 7.48663
314 6FA4 GNP 7.51445
315 5IRC GDP 7.52688
316 5DI3 GNP 7.56757
317 1YZN GNP 7.56757
318 5ZB0 TYD 7.57576
319 5ZB0 ADP 7.57576
320 3AQ4 GDP 7.6087
321 3CPJ GDP 7.62332
322 5W76 GDP 7.62712
323 5O2T GSP 7.69231
324 2ODE ALF GDP 7.71429
325 1MR3 G3D 7.73481
326 2BEK ATP 7.7821
327 4XSH GSP 7.82123
328 1OS1 PYR 7.82609
329 1OS1 ATP 7.82609
330 3DDN HPV 7.82609
331 5U32 GDP 7.8341
332 5HPY GDP 7.8341
333 4MKF AP5 7.8341
334 5XDR ADP 7.8341
335 4GOX A3P 7.8341
336 3VPD ANP 7.8341
337 1Y3A GDP 7.90274
338 2W58 ADP 7.9096
339 5TSH ADP 7.9096
340 5TSH ANP 7.9096
341 2NCD ADP 7.9096
342 2X77 GDP 7.93651
343 2OM2 GDP 8
344 1KO8 6PG 8
345 2WEL K88 8
346 1CS4 GSP 8.01887
347 4CVN ADP 8.0292
348 2QG6 NMN 8.0402
349 5HCN GCP 8.04598
350 3T1O GDP 8.08081
351 3T12 GDP ALF 8.08081
352 1TX4 ALF GDP 8.08081
353 4YLG GDP 8.09249
354 2HCJ GDP 8.10811
355 3DKP ADP 8.16327
356 4K81 GTP 8.18713
357 5M7P ADP 8.19209
358 1SVI GDP 8.20513
359 6BCB GSP 8.21918
360 4P3Y GDP 8.24176
361 1BH2 GSP 8.25397
362 1BG2 ADP 8.26087
363 2IS6 ADP 8.26087
364 3TBK ANP 8.26087
365 2GCO GNP 8.26087
366 2GCN GDP 8.26087
367 5IRN ADP 8.26087
368 1LCF OXL 8.26087
369 1F5N GNP 8.26087
370 4U00 ADP 8.29493
371 5BN3 ADP 8.29493
372 5VGR GDP 8.29493
373 3DZD ADP 8.29493
374 2D7D ADP 8.29493
375 1IBR GNP 8.29493
376 4TMZ GSP 8.29493
377 1X6V ADP 8.29493
378 4NCN GTP 8.29493
379 3ITJ CIT 8.29493
380 1K6M AGS 8.29493
381 5HR5 ADP 8.29493
382 1U8Z GDP 8.33333
383 4PU6 ASP 8.39695
384 1WQ1 GDP 8.43373
385 1CLU DBG 8.43373
386 1O3Y GTP 8.43373
387 1WQ1 AF3 8.43373
388 2J59 GTP 8.43373
389 3A4M ADP 8.47458
390 1V8K ANP 8.47458
391 4IEE AGS 8.47458
392 1H65 GDP 8.51852
393 1S9D GDP 8.53659
394 2B8W ALF 5GP 8.53659
395 4LHW GNP 8.62069
396 3QBT GNP 8.62069
397 3TNF GNP 8.62069
398 1OFH ADP 8.62069
399 5BXQ GDP 8.66142
400 6BC0 GSP 8.66667
401 1OXV ANP 8.69565
402 4YMU ATP 8.69565
403 2C9O ADP 8.69565
404 1KMQ GNP 8.69565
405 4Q1A 2XZ 8.69565
406 4Q1A UDP 8.69565
407 1KK1 GNP 8.75576
408 1WDT GTP 8.75576
409 1FNN ADP 8.75576
410 6H5E ANP 8.75576
411 4IDN GNP 8.75576
412 3VMF GTP 8.75706
413 1OYY AGS 8.75706
414 2XAU ADP 8.75706
415 3WXM GTP 8.75706
416 3DEF GDP 8.77863
417 1Z08 GNP 8.82353
418 1RYH GNP 8.86699
419 2PL3 ADP 8.8983
420 1QHH ATP 8.98204
421 5BQ5 ADP BEF 8.99471
422 5XKT GNP 9
423 3EC1 GDP 9.03955
424 5XC5 GTP 9.03955
425 3T34 GDP 9.03955
426 2G77 GDP 9.09091
427 4XGU ADP 9.13043
428 4DID GDP 9.13043
429 3E70 GDP 9.14634
430 4B47 GDP 9.21659
431 1MKY GDP 9.21659
432 5W75 GDP 9.21659
433 5KSZ GCP 9.21659
434 5FHD ADP ALF 9.21659
435 1U29 I3P 9.30233
436 6AIC AMP 9.34579
437 1I4D GDP 9.375
438 1Z06 GNP 9.52381
439 3BFV ADP 9.56522
440 5TIV A3P 9.56522
441 5WC2 ADP 9.60452
442 4HDO GNP 9.67742
443 4HDQ GNP 9.67742
444 3BFX A3P 9.67742
445 5UIV ADP 9.69163
446 3N5C GDP 9.87654
447 3PCR GTP 9.87654
448 1G3Q ADP 9.88701
449 6BVJ GNP 9.88701
450 6D5E GNP 9.88701
451 6D5G GNP 9.88701
452 6D5J GNP 9.88701
453 6BVK GNP 9.88701
454 6D5H GNP 9.88701
455 6BVL GNP 9.88701
456 1NVV GNP 9.88701
457 6D56 GNP 9.88701
458 6D5L GNP 9.88701
459 6BVM GNP 9.88701
460 6D59 GNP 9.88701
461 6BVI GNP 9.88701
462 6D5M GNP 9.88701
463 6D55 GNP 9.88701
464 6D5V GNP 9.88701
465 2WJG GDP 10
466 1F9V ADP 10
467 2WJH FLC 10
468 2WMO GTP 10
469 1GRN GDP 10
470 1A4R GNH 10
471 1A4R GDP 10
472 2WJH GDP 10
473 4YC7 GNP 10
474 1NF3 GNP 10
475 2NGR GDP 10
476 1GRN AF3 10
477 4FRZ ADP 10
478 1Q19 SSC 10
479 4HI0 GDP 10.0503
480 4V0K GDP 10.0592
481 2FJU GSP 10.1124
482 1XMV ADP 10.1382
483 4ITR GDP 10.1382
484 4H1V GNP 10.1382
485 2ZPT A3P 10.1382
486 5H68 AGS 10.1382
487 5NM7 GLY 10.1504
488 1VG9 GDP 10.1695
489 1VG0 GDP 10.1695
490 1HE1 GDP 10.2273
491 1HE1 AF3 10.2273
492 4TL6 ANP 10.2767
493 3H4S ADP 10.3704
494 5L3W GDP 10.4575
495 1M26 GAL A2G 10.5263
496 1E2K TMC 10.574
497 1R2Q GNP 10.5882
498 5LB3 ADP 10.5991
499 5LEF GTP 10.6061
500 1L2T ATP 10.6383
501 1X1R GDP 10.6742
502 3AB4 THR 10.6742
503 1NN5 ANP 10.6977
504 1NN5 2DT 10.6977
505 3MJH GTP 10.7143
506 2CHG ANP 10.7345
507 5L3S GNP 10.8108
508 5L3S G 10.8108
509 1E96 GTP 10.8374
510 5Z2M GTP 10.8696
511 1FQK GDP 10.8844
512 1FQK ALF 10.8844
513 5OEC GDP 10.929
514 1RE0 GDP 11.0599
515 4DCT GDP 11.0599
516 3GJX GTP 11.0599
517 4PJ3 ANP 11.0599
518 5UWI GNP 11.1111
519 3Q85 GNP 11.2426
520 4WZA ADP 11.3043
521 4WZA ACP 11.3043
522 2AWN ADP 11.3043
523 1XKV ATP 11.3043
524 3RLF ANP 11.3043
525 1WF3 GNP 11.3043
526 4OI4 ATP 11.3043
527 1G8S MET 11.3043
528 1QF5 GDP 11.3043
529 1QF5 RPL 11.3043
530 2V58 LZJ 11.3043
531 1T8U UAP SGN IDS SGN 11.3043
532 2CBZ ATP 11.3043
533 3CX8 GSP 11.33
534 1UKZ ADP 11.33
535 3FWY ADP 11.465
536 3UIE ANP 11.5
537 2Y65 ADP 11.5207
538 2ZFI ADP 11.5207
539 5I0H ADP BEF 11.5207
540 4ZI2 GNP 11.5789
541 4KBF AMP 11.5819
542 2OZE AGS 11.7391
543 2F5X ASP 11.7391
544 1ZJ6 G3D 11.7647
545 3WYG GTP 11.8421
546 2ZEJ GDP 11.9565
547 3A1S GDP 11.9816
548 5LTJ BEF 11.9816
549 5LTJ ADP 11.9816
550 4YS0 ADP 12.1469
551 1FZQ GDP 12.1547
552 1SKQ GDP 12.1739
553 4WZ6 ATP 12.1739
554 1R0X ATP 12.1739
555 4BFW ZVW 12.1739
556 2PZE ATP 12.2271
557 1Z0F GDP 12.2905
558 1TQ4 GDP 12.3487
559 1G16 GDP 12.3529
560 1IWE IMP 12.4294
561 2V5E SCR 12.5
562 1ZC3 GNP 12.5714
563 2ZR9 DTP 12.6087
564 4YJ1 ADP 12.6087
565 1KY3 GDP 12.6374
566 3DDC GNP 12.8834
567 4WOP CTP 12.8889
568 5GOE GDP 12.9032
569 2D2F ADP 12.9032
570 5L3R GCP 12.9032
571 3E5H GNP 12.9213
572 1GP2 GDP 12.9412
573 4PPF FLC 13.0435
574 1Z0K GTP 13.0435
575 5E5U MLI 13.0653
576 4D0G GTP 13.1429
577 5FG3 GDP 13.3641
578 1YTM ATP 13.3641
579 1DAR GDP 13.3641
580 5AK0 8V1 13.3641
581 1UPT GTP 13.4503
582 5EE5 GTP 13.4503
583 3LXR GDP 13.5417
584 2A5F GTP 13.7143
585 6A20 ADP 13.8249
586 5ZBR ANP 13.8249
587 3QF7 ANP 13.913
588 1HTW ADP 13.9241
589 1R4A GNP 13.9394
590 2EFE GNH 14.1243
591 4KAX GTP 14.2012
592 3GJ7 GDP 14.2857
593 6B4K ANP 14.2857
594 5XQL C2E 14.2857
595 2CUN 3PG 14.3478
596 5E95 GDP 14.433
597 5N69 ADP 14.5729
598 6BSX E7S 14.6067
599 6BSX GDP 14.6067
600 1P9B GDP 14.7465
601 4J0Q GDP 14.7826
602 4BQS ADP 14.7826
603 4BQS K2Q 14.7826
604 1Z6T ADP 15.2174
605 3CH5 GDP 15.3846
606 6C90 ADP 15.3846
607 2V2V V12 15.4982
608 4ZDJ UTP 15.5367
609 1J2J GTP 15.5556
610 1IN4 ADP 15.5689
611 2W83 GTP 15.5844
612 2HV8 GTP 15.625
613 4KVG GTP 15.6522
614 4XOI GTP 15.6522
615 5LV1 78T 15.6522
616 1WA5 GTP 15.6682
617 3P4X ADP 15.6682
618 3W5J GDP 15.6863
619 4GOJ GNP 15.873
620 3RAB GNP 15.9763
621 1Z2A GDP 16.0714
622 4R43 GDP 16.129
623 4E03 ADP 16.5049
624 1VKJ A3P 16.5899
625 5G3Y ADP 16.8142
626 2CDN ADP 16.9154
627 2VB6 ADP BEF 17.0507
628 4PFO ADP 17.0507
629 2CJW GDP 17.1875
630 1LFD GNP 17.2414
631 4PC3 GDP 17.5115
632 3WYF GTP 17.5115
633 5X40 ACP 17.5115
634 1W0J ADP BEF 17.8261
635 2CK3 ADP 17.8261
636 1W0J ADP 17.8261
637 2CK3 ANP 17.8261
638 2V7Q ADP 17.8261
639 2V7Q ATP 17.8261
640 2C5L GTP 17.9487
641 5K5Z ANP 18.0791
642 1UAD GNP 18.1818
643 4LJ9 ACP 18.3616
644 1APZ ASP 18.4397
645 5IRR GSP 18.6441
646 5UPK GNP 18.75
647 1Z0J GTP 18.8235
648 1YVD GNP 18.9349
649 2HT6 GDP 18.9655
650 2KIN ADP 19
651 1FQJ GDP 19.0476
652 1FQJ ALF 19.0476
653 1F2U ATP 19.4631
654 3GJ8 GDP 19.5652
655 2VOH CIT 20
656 5KDO GDP 20.2703
657 1R6B ADP 20.339
658 1GOT GDP 20.5479
659 1XX6 ADP 20.9424
660 1LLU NAD 21.1982
661 1GXU 2HP 21.978
662 3T5G GDP 22.3684
663 1KSH GDP 22.3684
664 5TB5 GDP 22.6667
665 5TAR GDP 22.973
666 1CXZ GSP 23.2558
667 1VHT BA3 23.3945
668 5WLB GNP 23.5294
669 3GJ3 GDP 24.2424
670 3ZIA ADP 24.5763
671 3ZIA ATP 24.5763
672 3REF GDP 24.7423
673 3B5J 12D 24.8848
674 1M2O GNP 25.2632
675 1G7C 5GP 26.5957
676 3KUD GDP 27.1605
677 1GUA GNP 27.1605
678 5H67 ATP 27.5
679 5YV5 ADP 27.6498
680 1YQT ADP 27.6498
681 6CIT GNP 28.5714
682 2QTV GNP 28.7425
683 5UWH GNP 31.8182
684 2W2X GSP 34.6774
685 5UWO GNP 35
686 3GJ5 GDP 35.2941
687 1IHU AF3 35.5932
688 1IHU ADP 35.5932
689 5YT0 GDP 38.0952
690 1TU3 GNP 39.2405
691 6CRK GDP 40
Pocket No.: 2; Query (leader) PDB : 4XVU; Ligand: ATP; Similar sites found with APoc: 20
This union binding pocket(no: 2) in the query (biounit: 4xvu.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1Q20 PLO 3.34448
2 1Q20 A3P 3.34448
3 3P7G MAN 4.10959
4 3FXU TSU 4.2623
5 4Z7X 3CX 4.60829
6 1QB7 ADE 4.78261
7 1RL4 BRR 4.78723
8 1JOT GAL A2G 6.76692
9 4AKB GAL 6.76692
10 4PYA 2X3 7.45342
11 3TMK T5A 8.33333
12 3L6R MLI 8.3815
13 4XQC 13D 9.03955
14 2G77 AF3 9.09091
15 1X9I G6Q 9.67742
16 1X8J A3P 9.67742
17 3OND NAD 10.1382
18 3OND ADN 10.1382
19 1P4V GLY 11.3043
20 5LXT GDP 13.4831
Pocket No.: 3; Query (leader) PDB : 4XVU; Ligand: ATP; Similar sites found with APoc: 34
This union binding pocket(no: 3) in the query (biounit: 4xvu.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 6HKE LMR 3.45912
2 6HKE MLT 3.45912
3 1IG0 VIB 4.07523
4 3BY9 SIN 4.14747
5 1AUX AGS 4.51977
6 1M3U KPL 4.92424
7 1A8S PPI 5.21739
8 1Z45 GAL 5.52995
9 3VEH 0GA 5.65217
10 3GM5 CIT 5.66038
11 4XCB AKG 5.74713
12 4IF4 BEF 5.76923
13 4C2C ALA ALA ALA 6.21469
14 4JBL MET 6.52174
15 3JYY PPV 6.95652
16 2QQ0 ANP 7.06522
17 2QQ0 THM 7.06522
18 2QQ0 TMP 7.06522
19 2QQ0 ADP 7.06522
20 1TKU 5RP 7.35294
21 1V35 NAI 7.37327
22 2P3V SRT 7.8125
23 2VQD AP2 8.18966
24 1WS4 GYP 10.5263
25 1UGW GAL 10.5263
26 1TOQ AMG 10.5263
27 2BO4 FLC 10.5991
28 1B4U DHB 10.7914
29 2O66 FLC 11.1111
30 1W4R TTP 11.7949
31 3QDK QDK 11.8644
32 5BOE PEP 13.8249
33 1P9B HDA 14.7465
34 3ABI NAD 16.129
Pocket No.: 4; Query (leader) PDB : 4XVU; Ligand: ATP; Similar sites found with APoc: 7
This union binding pocket(no: 4) in the query (biounit: 4xvu.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 3GDN HBX 5.52995
2 4WEI GLC GAL 7.94224
3 4NTD FAD 8.29493
4 4AQ0 DMJ 8.69565
5 1W3T 3GR 9.67742
6 2ORV 4TA 9.82906
7 2NGR AF3 10
APoc FAQ
Feedback