Receptor
PDB id Resolution Class Description Source Keywords
4XIZ 2 Å NON-ENZYME: OTHER STRUCTURE OF A PHOSPHOLIPID TRAFFICKING COMPLEX WITH SUBSTRA SACCHAROMYCES CEREVISIAE (STRAIN ATCC S288C) PHOSPHOLIPID LIPID TRANSPORT-OXIDOREDUCTASE COMPLEX
Ref.: STRUCTURAL BASIS OF INTRAMITOCHONDRIAL PHOSPHATIDIC TRANSPORT MEDIATED BY UPS1-MDM35 COMPLEX EMBO REP. V. 16 813 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LPP A:201;
B:201;
 Valid;
Valid;
 none;
none;
 submit data
648.891 C35 H69 O8 P CCCCC...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XIZ 2 Å NON-ENZYME: OTHER STRUCTURE OF A PHOSPHOLIPID TRAFFICKING COMPLEX WITH SUBSTRA SACCHAROMYCES CEREVISIAE (STRAIN ATCC S288C) PHOSPHOLIPID LIPID TRANSPORT-OXIDOREDUCTASE COMPLEX
Ref.: STRUCTURAL BASIS OF INTRAMITOCHONDRIAL PHOSPHATIDIC TRANSPORT MEDIATED BY UPS1-MDM35 COMPLEX EMBO REP. V. 16 813 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4XIZ - LPP C35 H69 O8 P CCCCCCCCCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4XIZ - LPP C35 H69 O8 P CCCCCCCCCC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 4XIZ - LPP C35 H69 O8 P CCCCCCCCCC....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: LPP; Similar ligands found: 117
No: Ligand ECFP6 Tc MDL keys Tc
1 3PH 1 1
2 F57 1 1
3 7PH 1 1
4 6PH 1 1
5 LPP 1 1
6 7P9 0.980392 1
7 PD7 0.921569 1
8 M7U 0.847458 1
9 D21 0.847458 0.976744
10 44E 0.846154 1
11 PX8 0.803571 0.930233
12 PX2 0.803571 0.930233
13 PA8 0.785714 0.930233
14 TGL 0.745098 0.690476
15 CD4 0.725806 0.953488
16 PEV 0.714286 0.788462
17 PTY 0.714286 0.788462
18 3PE 0.714286 0.788462
19 8PE 0.714286 0.788462
20 PEH 0.714286 0.788462
21 PEF 0.714286 0.788462
22 PGT 0.703125 0.911111
23 PEE 0.703125 0.773585
24 LHG 0.703125 0.911111
25 9PE 0.703125 0.788462
26 CDL 0.6875 0.863636
27 PLD 0.681818 0.727273
28 HGP 0.681818 0.727273
29 PC7 0.681818 0.727273
30 PX4 0.681818 0.727273
31 P5S 0.681818 0.803922
32 HGX 0.681818 0.727273
33 6PL 0.681818 0.727273
34 LIO 0.681818 0.727273
35 8SP 0.666667 0.803922
36 PII 0.661765 0.836735
37 PG8 0.651515 0.869565
38 PIF 0.642857 0.857143
39 CN3 0.642857 0.953488
40 DDR 0.631579 0.697674
41 FAW 0.631579 0.697674
42 1EM 0.631579 0.697674
43 L2C 0.631579 0.697674
44 DGA 0.631579 0.697674
45 PIZ 0.630137 0.875
46 XP5 0.626866 0.727273
47 LOP 0.625 0.773585
48 6OU 0.625 0.773585
49 L9Q 0.625 0.773585
50 MC3 0.623188 0.685185
51 PC1 0.623188 0.685185
52 PCF 0.623188 0.685185
53 52N 0.616438 0.857143
54 D3D 0.616438 0.891304
55 IP9 0.616438 0.875
56 PGW 0.616438 0.891304
57 PIO 0.616438 0.857143
58 RXY 0.616438 0.773585
59 CN6 0.614286 0.953488
60 NKO 0.610169 0.953488
61 NKN 0.610169 0.953488
62 AGA 0.608696 0.869565
63 PGV 0.608108 0.891304
64 DR9 0.608108 0.891304
65 PGK 0.6 0.854167
66 PCW 0.6 0.714286
67 P6L 0.6 0.891304
68 P50 0.592105 0.803922
69 OZ2 0.592105 0.891304
70 44G 0.590909 0.911111
71 ZPE 0.586667 0.773585
72 PCK 0.584416 0.689655
73 B7N 0.584416 0.82
74 DGG 0.576923 0.854167
75 HXG 0.573529 0.727273
76 PSF 0.573529 0.803922
77 GP7 0.5625 0.773585
78 LBR 0.5625 0.644444
79 PEK 0.556962 0.773585
80 P3A 0.556962 0.851064
81 PIE 0.556962 0.764706
82 L9R 0.551282 0.672727
83 LBN 0.551282 0.672727
84 POV 0.551282 0.672727
85 PSC 0.548781 0.714286
86 NKP 0.529412 0.931818
87 2JT 0.527273 0.659091
88 G2A 0.527273 0.659091
89 T7X 0.517647 0.82
90 PDK 0.505618 0.683333
91 SQD 0.5 0.609375
92 EKG 0.491525 0.644444
93 1QW 0.491525 0.644444
94 GYM 0.491525 0.644444
95 BQ9 0.486486 0.681818
96 LPX 0.485714 0.769231
97 DLP 0.482353 0.672727
98 EPH 0.466667 0.773585
99 LP3 0.465753 0.732143
100 LPC 0.465753 0.732143
101 LAP 0.465753 0.732143
102 K6G 0.465753 0.732143
103 PGM 0.457143 0.847826
104 87O 0.45614 0.813953
105 PC5 0.432432 0.603448
106 3PC 0.428571 0.666667
107 PVC 0.426471 0.625
108 OLB 0.426471 0.630435
109 OLC 0.426471 0.630435
110 CN5 0.421053 0.931818
111 42H 0.414634 0.719298
112 I35 0.413333 0.8125
113 DB4 0.413333 0.795918
114 NTK 0.410714 0.619048
115 PBU 0.410256 0.795918
116 MVC 0.405797 0.630435
117 S12 0.402439 0.769231
Similar Ligands (3D)
Ligand no: 1; Ligand: LPP; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4XIZ; Ligand: LPP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4xiz.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4XIZ; Ligand: LPP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4xiz.bio2) has 33 residues
No: Leader PDB Ligand Sequence Similarity
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