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Receptor
PDB id Resolution Class Description Source Keywords
4XHG 2.15 Å NON-ENZYME: OTHER STRUCTURE OF C. GLABRATA HRR25 BOUND TO ADP (FORMATE CONDITI CANDIDA GLABRATA CASEIN KINASE MONOPOLIN TRANSFERASE
Ref.: STRUCTURE OF THE SACCHAROMYCES CEREVISIAE HRR25:MAM MONOPOLIN SUBCOMPLEX REVEALS A NOVEL KINASE REGULAT EMBO J. V. 35 2139 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:501;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
FMT A:502;
Invalid;
none;
submit data
46.025 C H2 O2 C(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XH0 1.99 Å NON-ENZYME: OTHER STRUCTURE OF C. GLABRATA HRR25 BOUND TO ADP (SO4 CONDITION) CANDIDA GLABRATA CASEIN KINASE MONOPOLIN TRANSFERASE
Ref.: STRUCTURE OF THE SACCHAROMYCES CEREVISIAE HRR25:MAM MONOPOLIN SUBCOMPLEX REVEALS A NOVEL KINASE REGULAT EMBO J. V. 35 2139 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4XH0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4XHG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4XH0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4XHG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4XH0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4XHG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 4KBA ic50 = 654 nM 1QM C18 H17 F N4 O Cn1cc(c(n1....
4 4KBC - 1QJ C15 H12 F N3 O c1cc(ccc1c....
5 4TWC - 37J C20 H11 F6 N5 O3 S c1ccc(c(c1....
6 4HNF ic50 = 711 nM 16W C17 H18 Cl N5 O2 c1cc(cc(c1....
7 4BTK Kd = 0.24 uM DTQ C16 H15 N3 O3 COc1cc2c(c....
8 5IH5 ic50 = 0.5 uM AUE C12 H10 Cl N7 c1cc(cc(c1....
9 5MQV ic50 = 8 nM D5Q C29 H26 F N5 O3 S Cn1cc(cc1C....
10 3UZP - 0CK C19 H20 F N5 c1cc(ccc1c....
11 5W4W ic50 = 8 nM 9WG C18 H15 F N4 O Cn1cc(c(n1....
12 4TW9 ic50 = 0.02 uM 386 C20 H10 F5 N5 O5 S c1ccc(c(c1....
13 5X17 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
14 6GZM - LCI C18 H26 F N6 Cn1c(c(cn1....
15 5IH6 ic50 = 2.5 uM AUG C12 H10 Br N7 c1cc(cc(c1....
16 3UYT - 0CK C19 H20 F N5 c1cc(ccc1c....
17 4KB8 ic50 = 3040 nM 1QN C17 H17 F N4 CNCc1cc(cc....
18 4KBK - 1QG C19 H19 F N4 O Cn1cc(c(n1....
19 6GZD Kd = 9.8 nM LCI C18 H26 F N6 Cn1c(c(cn1....
20 4NFN ic50 = 120 nM 2KC C19 H23 Br N6 O CC1(CCN(CC....
21 2CSN Ki = 39 uM CKI C11 H12 Cl N3 O2 S c1cc(c2ccn....
22 1CSN - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
23 4G17 ic50 = 0.029 uM 0VN C18 H18 N4 CC(C)(C)c1....
24 4G16 ic50 = 0.14 uM 0VM C20 H12 F3 N5 O c1cc(c(nc1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4XH0; Ligand: ADP; Similar sites found with APoc: 524
This union binding pocket(no: 1) in the query (biounit: 4xh0.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5HP8 PYR None
2 6HH6 A3R 1.24069
3 5I35 ANP 1.27226
4 1KJ8 ATP 1.27877
5 1KJ8 GAR 1.27877
6 4I94 ANP 1.33333
7 4C5N PXL 1.44928
8 4C5N ACP 1.44928
9 2PYW ADP 1.48883
10 2XOC ADP 1.53257
11 3WSJ MK1 1.72414
12 3UDZ ADP 1.73697
13 2IO8 ADP 1.73697
14 2X3F APC 1.75439
15 1HZP DAO 1.79104
16 2VZ0 NAP 1.86567
17 2VZ0 D64 1.86567
18 1ZB6 DIN 1.9544
19 5MW8 ATP 1.98511
20 5TT5 NAD 1.98511
21 2QF7 AGS 1.98511
22 4PZ6 GMP 1.98511
23 2VBF TPP 1.98511
24 2Q4H AMP 1.9943
25 5FCF GLY GLY GLY 2.00501
26 4GYI ADP 2.01511
27 2Q7D ANP 2.02312
28 2FB3 GTP 2.05882
29 2FB3 MET 2.05882
30 2FB3 5AD 2.05882
31 4NFE BEN 2.1097
32 4NZN ANP 2.12121
33 4NZN 2OU 2.12121
34 1EHI ADP 2.12202
35 4LJ3 C2E 2.15054
36 3AKK ADP 2.15385
37 1Z2P ACP 2.16049
38 1Z2P I3S 2.16049
39 4K37 SAM 2.16216
40 4K39 SAM 2.16216
41 4CC6 L5Y 2.20126
42 2R7K AMZ 2.21607
43 2R7K ACP 2.21607
44 2VPQ ANP 2.23325
45 2OO0 PLP 2.23325
46 3KFL ME8 2.23325
47 4DJA FAD 2.23325
48 4DJA DLZ 2.23325
49 3K5I ADP 2.23325
50 3K5I AIR 2.23325
51 2NP9 YE1 2.23325
52 3TY5 ATP 2.23325
53 3TY5 ADP 2.23325
54 1NJJ ORX 2.23325
55 3ETH ATP 2.25352
56 3V4S ATP 2.32558
57 3V4S ADP 2.32558
58 3ZS7 ATP 2.33333
59 4ZGP ADP 2.38908
60 1EIX BMQ 2.44898
61 2IF8 ADP 2.47934
62 1M0W ANP 2.48139
63 5VZ0 ADP 2.48139
64 4CYI ATP 2.48139
65 5JFL NAD 2.48139
66 1GSA ADP 2.53165
67 3NC9 TR3 2.55591
68 4AUT FAD 2.5641
69 3FUU ADN 2.58303
70 5C1P DAL DAL 2.61438
71 5C1P ADP 2.61438
72 5YLT C7N 2.6616
73 5YLT SFG 2.6616
74 3BEO UDP 2.66667
75 2HW1 ANP 2.68456
76 3KAL ADP 2.72953
77 5DXT 5H5 2.72953
78 1PVN MZP 2.92553
79 1IOW PHY 2.94118
80 1IOW ADP 2.94118
81 2GQS ADP 2.95359
82 2GQR ADP 2.95359
83 2YW2 ATP 2.97767
84 1OX5 1PR 2.97767
85 3B2Q ATP 2.97767
86 4ZFL 4NK 2.99145
87 4YHQ G10 3.0303
88 4I5I NAD 3.13589
89 3W0O HY0 3.15186
90 3W0O ADP 3.15186
91 1A8R GTP 3.16742
92 3VOT ADP 3.22581
93 2YPO PHE 3.22581
94 1MXH DHF 3.26087
95 1MXH NAP 3.26087
96 6CGD AKN 3.27869
97 6CGD GNP 3.27869
98 1ERB ETR 3.27869
99 3FSY SCA 3.31325
100 5IGI ZIT 3.32226
101 5IGI GMP 3.32226
102 4LH7 1X8 3.40557
103 3BP1 GUN 3.44828
104 3PN1 IVH 3.45912
105 1K7L 544 3.47222
106 3WO0 ADP 3.47395
107 3WO0 ALA 3.47395
108 2HGS ADP 3.47395
109 2YRX AMP 3.47395
110 5KOR GDP 3.47395
111 4B0T ADP 3.47395
112 4HKP 16B 3.52564
113 4HKP TKW 3.52564
114 4EN4 GT1 3.52564
115 4EN4 ATP 3.52564
116 4EN4 GT0 3.52564
117 5COU ATP 3.52941
118 1NY5 ADP 3.61757
119 2QTR NXX 3.7037
120 2H29 DND 3.7037
121 3ORQ ADP 3.71353
122 4QYS PLP SEP 3.72208
123 4WOE 3S5 3.72208
124 4XZ3 ACP 3.72208
125 1CBK ROI 3.75
126 2QX0 PH2 3.77358
127 1E4E ADP 3.79009
128 2PID YSA 3.93258
129 2DTJ THR 3.93258
130 3AB4 THR 3.93258
131 5YK1 ANP 3.97022
132 6C8X BVR 4.0404
133 3E3U NVC 4.06091
134 5T9C G3P 4.10448
135 5OES ADP 4.21836
136 1T36 ADP 4.21836
137 5TDF ADP 4.21836
138 2BMB PMM 4.21836
139 4OCV ANP 4.22164
140 2QCD U5P 4.23077
141 4EWN 0VR 4.34783
142 4NJH 2K8 4.34783
143 4NJH SAM 4.34783
144 1TZD ADP 4.36364
145 1X1Z BMP 4.36508
146 2Q8Z NUP 4.38596
147 1NZY BCA 4.46097
148 1JXZ BCA 4.46097
149 2V58 LZJ 4.4665
150 4MV1 ADP 4.4665
151 4OCJ NDG 4.48549
152 1W2D ADP 4.5283
153 1W2D 4IP 4.5283
154 2QK4 ATP 4.71464
155 1OBD ATP 4.71464
156 5OLK DTP 4.71464
157 2CFM AMP 4.71464
158 1JG3 ADN 4.71464
159 4ELG 52J 4.81928
160 4ELG 52I 4.81928
161 3GNI ATP 4.88432
162 4UWH JXM 4.96278
163 3NRR UMP 4.96278
164 5G5G MCN 5.03145
165 1DQE BOM 5.10949
166 2WSB NAD 5.11811
167 4K49 HFQ 5.14706
168 1IIU RTL 5.17241
169 1S68 AMP 5.22088
170 5EQY 5RA 5.23691
171 6G34 5ID 5.32213
172 4OUC 5ID 5.32213
173 4KWD JF2 5.41401
174 3DLG GWE 5.45906
175 3T1A 5MA 5.45906
176 4R78 AMP 5.50162
177 4IEN GDP 5.52147
178 4GLW 0XT 5.57377
179 3X01 AMP 5.59796
180 5AE9 OKO 5.7072
181 6EZ6 C5Z 5.7072
182 1LCK GLU GLY GLN PTR GLN PRO GLN PRO ALA 5.71429
183 2Q4V ACO 5.88235
184 3I0O ADP 5.8997
185 4LRJ ANP 5.91716
186 1DQX BMP 5.99251
187 3HAV ATP 6.02007
188 4LCN GNG 6.09137
189 4O1P ANP 6.20347
190 4WVO 3UZ 6.20347
191 4WOP CTP 6.22222
192 1W6U HXC 6.29139
193 2ZYI STE 6.31579
194 4AZ3 S35 6.33333
195 4O4F ATP 6.45161
196 4O4F IHP 6.45161
197 4K4D HFQ 6.56934
198 5DMZ ADP 6.57534
199 6ES0 BW8 6.62461
200 3KMW ATP 6.64207
201 1CKM GTP 6.66667
202 4CRL C1I 6.69975
203 3RGA LSB 6.71378
204 1IA9 ANP 6.78571
205 3KDJ A8S 6.93069
206 6FL8 TIY 6.94789
207 6FL8 ADP 6.94789
208 2PZI AXX 6.94789
209 6C1S EFV 6.94789
210 3HKW IX6 6.94789
211 4U98 ACP 7.19603
212 2B9J ADP 7.36544
213 2B9I ADP 7.36544
214 2B9H ADP 7.36544
215 4XYM A12 7.3913
216 1IHU ADP 7.44417
217 1IHU AF3 7.44417
218 4Y0X ADP 7.46667
219 6GIN IR2 7.6412
220 3RE4 TO1 7.75194
221 1ZTH ADP 7.75194
222 1ZP9 ATP 7.75194
223 4FE2 ADP 7.84314
224 1ONI BEZ 7.97101
225 2GAG FAD 8.08081
226 2GAG FOA 8.08081
227 4IJP 1EH 8.10056
228 3TXO 07U 8.2153
229 3H9R TAK 8.25688
230 2AQX ATP 8.3045
231 3M2W L8I 8.3612
232 3TTI KBI 8.68486
233 2UUU FAD 8.68486
234 5ZCT ANP 8.82353
235 5GZ9 ANP 8.85246
236 1TQP ATP 8.86525
237 3VX3 ADP 8.87097
238 4FG8 ATP 8.88889
239 3SXS PP2 8.95522
240 4WHZ 3NL 9.09091
241 2OO8 RAJ 9.14826
242 5FI4 5XV 9.18114
243 1NBU PH2 9.2437
244 1Y8Q ATP 9.24856
245 3PTG 932 9.36639
246 5M06 ADP 9.42029
247 3LXK MI1 9.48012
248 2X2M X2M 9.55414
249 3VPD ANP 9.60854
250 3T4L ZEA 9.62963
251 3Q60 ATP 9.7035
252 6DW2 HD4 9.70464
253 4AUA 4AU 9.77199
254 2BKK ADP 9.84848
255 1Y0G 8PP 9.94764
256 1VKF CIT 10.1064
257 2XVD AS6 10.2649
258 5A5W GUO 10.2767
259 5VCV 1N1 10.2894
260 5DQ8 FLF 10.4167
261 2VQD AP2 10.67
262 4X3R 686 10.67
263 3H4V DVP 10.7639
264 3H4V NAP 10.7639
265 3EXS 5RP 10.8597
266 5KO1 6UY 10.9541
267 3VPB ADP 10.9929
268 3VPC ADP 10.9929
269 2RIO ADP 11.2903
270 2PUL ACP 11.335
271 4YZC STU 11.4144
272 4OAV ACP 11.4144
273 5IM3 DTP 11.6625
274 6BXI ANP 12.012
275 5QIN J2V 12.0253
276 2B9F ADP 12.4646
277 3TM0 ANP 12.5475
278 3TM0 B31 12.5475
279 4Q5H ANP 12.6437
280 2QLU ADE 13.0573
281 3FHR P4O 13.0952
282 5USZ SKE 13.1488
283 5Y6Q MCN 13.3995
284 6C0T EE4 13.5447
285 3IGO ANP 13.6476
286 4UX9 ANP 13.7363
287 5H5F SAM 14.1026
288 5TA6 79D 14.2458
289 2R5T ANP 14.4772
290 3C0G 3AM 14.5299
291 4ZS4 ATP 14.658
292 4DC2 ADE 14.899
293 3HMO STU 14.9123
294 1XJD STU 15.0725
295 4PNI KQQ 15.1365
296 4L9I 8PR 15.1365
297 3FC2 IBI 15.2239
298 4ASE AV9 15.2975
299 6CMJ F6J 15.5763
300 3VHE 42Q 15.5989
301 4Y93 746 15.8809
302 2WU6 DKI 16.0105
303 5N87 N66 16.2939
304 3PDT ADP 16.3636
305 5LI1 ANP 16.6667
306 2ZV2 609 16.7785
307 1ZY5 ANP 16.8317
308 5LI9 ACP 16.8571
309 4AT3 LTI 17.0569
310 5Y86 HRM 17.1216
311 5JFS 6K0 17.2078
312 5JKG 6LF 17.3633
313 4QTB 38Z 17.3684
314 4K33 ACP 17.5385
315 2JLD AG1 17.6179
316 3V8S 0HD 17.6179
317 5MY8 RXZ 17.7546
318 5EH0 5NW 17.8295
319 1Q8Y ADE 17.9625
320 1Q8Y ADP 17.9625
321 4H3P ANP 18.232
322 2PVF ACP 18.2635
323 5BVE 4VG 18.2825
324 4H3Q ANP 18.5083
325 3GQI ACP 18.7117
326 2JDR L20 18.7134
327 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 18.7134
328 4P5Z Q7M 18.8366
329 5EKO N17 18.8679
330 6BFN DL1 19.0058
331 3ZRM ZRM 19.1375
332 5OMY 9YE 19.1816
333 3RI1 3RH 19.4888
334 2WEI VGG 19.5122
335 5UR1 YY9 19.6141
336 1CM8 ANP 19.6185
337 3LXN MI1 19.8113
338 5WNL STU 19.883
339 5CEO 50D 20
340 4JR7 GNP 20.0535
341 4F9C 0SX 20.2216
342 3UIM ANP 20.2454
343 3F7Z 34O 20.2857
344 3GC8 B45 20.5405
345 5HVJ ANP 20.6349
346 4GJ3 0XP 20.8609
347 3PP0 03Q 21.0059
348 2YAK OSV 21.0526
349 1PHK ATP 21.1409
350 5WO4 B7V 21.1921
351 1OUK 084 21.3115
352 4A4X JUP 21.5054
353 4UAL 3FV 21.5881
354 4AU8 Z3R 21.6216
355 4UXL 5P8 21.7391
356 1UNH IXM 21.9178
357 3O0G 3O0 21.9178
358 4IZY 1J2 21.9512
359 2V7O DRN 22.0238
360 1JPA ANP 22.1154
361 2PVN P63 22.1591
362 6C7Y ADP 22.3776
363 5YF9 NIO 22.4189
364 3PE2 E1B 22.5519
365 4E1Z 0MX 22.6804
366 2J7T 274 22.8477
367 5NKB 8ZT 22.8758
368 5MJA 7O3 22.9508
369 3DAK ANP 23.1034
370 2F2U M77 23.1343
371 6CQF F97 23.2323
372 2WEL K88 23.2416
373 3HZT J60 23.3251
374 5JGA 6KC 23.4921
375 5VC5 96M 23.5294
376 5JZJ AN2 23.569
377 4NST ADP 23.6467
378 4ONA UW1 23.8213
379 3PLS ANP 23.8255
380 1U5R ATP 23.8506
381 4M69 ANP 24.0283
382 2Y6O 1N1 24.055
383 3E7O 35F 24.1667
384 2VZ6 FEF 24.3176
385 6GWR FEW 24.4444
386 6FYL 3NG 24.5179
387 4WNK 453 24.5658
388 1VJY 460 24.7525
389 4WB7 ATP 24.8139
390 4N70 2HX 25
391 5DRB 5FJ 25.0859
392 5T8O 76Z 25.2149
393 2VN9 GVD 25.2492
394 4X7Q 3YR 25.3205
395 5EFQ ADP 25.3602
396 3KN5 ANP 25.5385
397 4IDT T28 25.5618
398 4OH4 ANP 25.8258
399 4Y85 499 25.9036
400 5UPK ANP 26.0116
401 2YAB AMP 26.0388
402 3PVW QRX 26.0546
403 3CY2 MB9 26.1146
404 3GC0 AMP 26.1398
405 3ALN ANP 26.2997
406 5UKL SIX 26.3027
407 2OFV 242 26.3538
408 3E8N VRA 26.393
409 3E8N ATP 26.393
410 2H8H H8H 26.5509
411 1Y57 MPZ 26.5509
412 5X8I SQZ 26.5896
413 5UIU 8CG 26.6254
414 4OTH DRN 26.6862
415 4U44 3D9 26.8072
416 3BZ3 YAM 26.8116
417 3MVH WFE 26.9006
418 6A1G 9OL 26.9444
419 3VRY B43 27.0471
420 6G33 5ID 27.1386
421 5AWM ANP 27.1574
422 4CLI 5P8 27.2171
423 4E93 GUI 27.321
424 1OPK P16 27.5434
425 4QMN DB8 27.7419
426 2BPM 529 27.8317
427 3KRL KRL 28.0597
428 5C03 AGS 28.0702
429 4BHN BH9 28.1437
430 5DH3 5BS 28.254
431 4FL3 ANP 28.2878
432 3RWP ABQ 28.2958
433 5TO8 7FM 28.3688
434 4CFU 2WC 28.3828
435 6GUE FB8 28.4768
436 6GU6 1QK 28.5714
437 2QCS ANP 28.5714
438 5HQ0 LZ9 28.5714
439 4BCM T7Z 28.5714
440 4BCQ TJF 28.5714
441 4BCN T9N 28.6667
442 4WB6 ATP 28.8571
443 3IDB ANP 28.8571
444 3FHI ANP 28.8571
445 1RE8 BD2 28.8571
446 2XMY CDK 28.8591
447 5AX9 4KT 28.8961
448 3ORK AGS 28.9389
449 4USF 6UI 28.9474
450 5LMK 6ZK 28.9562
451 2F57 23D 29.0221
452 4BFM ANP 29.0419
453 4KS7 X4Z 29.1096
454 6F3G CJN 29.1525
455 5IH9 6BF 29.2537
456 6FYV 3NG 29.3769
457 3TKI S25 29.4118
458 2HY0 306 29.5031
459 5FBN 5WF 29.5203
460 2GU8 796 29.6736
461 5EYK 5U5 29.7101
462 4Y8D 49J 30
463 5XVG 8FX 30.0341
464 2A19 ANP 30.2817
465 4AG8 AXI 30.3797
466 2XK9 XK9 30.7453
467 3DLS ADP 30.7463
468 4C2W ANP 30.7692
469 5DEY 59T 30.9764
470 4LOO SB4 31.0345
471 3C1X CKK 31.3673
472 1V0O INR 31.5972
473 4C2V YJA 31.8182
474 6E2O S0L 31.8644
475 5L8L ADP 31.9298
476 5G1X ADP 31.9298
477 4EUU BX7 31.9749
478 2Z7R STU 32.0872
479 5LXM ADP 32.1555
480 3AQV TAK 32.2464
481 4I6H 1C8 32.4675
482 5Y80 IRE 32.5879
483 5ODT ADP 32.6087
484 4WOV 3SM 32.8076
485 4NW6 2NS 33.1269
486 5LVP ATP 33.3333
487 5U6C 7YS 33.3333
488 4WNP 3RJ 33.4495
489 5EW9 5VC 33.5793
490 3E5A VX6 33.9552
491 5HCY 60D 34.139
492 4YMJ 4EJ 34.2105
493 5A6N U7E 34.2756
494 4G31 0WH 34.7826
495 4L3L 5FI 34.8684
496 5EOB 5QQ 35.4232
497 3GGF GVD 36.2126
498 1BYG STU 36.3309
499 4U0I 0LI 36.5079
500 4ITH RCM 36.7347
501 5HES 032 36.8078
502 3SLS ANP 36.8421
503 6GQM F8H 36.8902
504 3G5D 1N1 37.0629
505 4NM5 ADP 37.5
506 6AC9 ANP 37.8378
507 4CSV STI 38.5455
508 3NW7 LGV 39.0879
509 2HK5 1BM 39.2593
510 5H2U 1N1 39.3258
511 4YZN 4K5 39.3728
512 6CZ3 FLJ 39.7727
513 1IR3 ANP 39.8693
514 1K3A ACP 40.1338
515 3BU5 ATP 40.1961
516 3EKK GS2 40.3909
517 2WQN ADP 40.6452
518 3SRV S19 41.1552
519 4TWP AXI 41.3284
520 4F4P 0SB 41.3919
521 4EWH T77 41.4545
522 4XV1 904 42.4658
523 1U59 STU 42.8571
524 4CQE CQE 44.6043
525 1O9U ADZ 50
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