-->
Receptor
PDB id Resolution Class Description Source Keywords
4XGU 2.3 Å NON-ENZYME: OTHER STRUCTURE OF C. ELEGANS PCH-2 CAENORHABDITIS ELEGANS MEIOTIC RECOMBINATION AAA+ ATPASE PROTEIN REMODELER ATP-BPROTEIN
Ref.: TRIP13 IS A PROTEIN-REMODELING AAA+ ATPASE THAT CAT MAD2 CONFORMATION SWITCHING. ELIFE V. 4 07367 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP E:503;
B:501;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
SO4 F:501;
E:501;
D:502;
A:501;
C:501;
E:502;
D:501;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XGU 2.3 Å NON-ENZYME: OTHER STRUCTURE OF C. ELEGANS PCH-2 CAENORHABDITIS ELEGANS MEIOTIC RECOMBINATION AAA+ ATPASE PROTEIN REMODELER ATP-BPROTEIN
Ref.: TRIP13 IS A PROTEIN-REMODELING AAA+ ATPASE THAT CAT MAD2 CONFORMATION SWITCHING. ELIFE V. 4 07367 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4XGU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4XGU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4XGU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4XGU; Ligand: ADP; Similar sites found with APoc: 570
This union binding pocket(no: 1) in the query (biounit: 4xgu.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 4QM7 GTP None
2 1F5N GNP 1.17925
3 5I34 GDP 1.17925
4 1G7C 5GP 1.41509
5 2NCD ADP 1.42857
6 1UGY GLA BGC 1.50376
7 2WKQ GTP 1.50602
8 2B8W ALF 5GP 1.52439
9 3VX3 ADP 1.6129
10 1FGX U5P 1.73611
11 6EK3 OUL 1.80995
12 1Y3A GDP 1.82371
13 4A4Z ANP 1.88679
14 3EC1 GDP 1.89702
15 1BH2 GSP 1.90476
16 4KBF AMP 1.91781
17 5YT0 GDP 1.92308
18 4RD0 GDP 1.92771
19 5KUT GDP 2.1164
20 5M04 GDP 2.12264
21 5KSZ GCP 2.12264
22 2DPY ADP 2.12264
23 1OYY AGS 2.12264
24 2XZ9 PYR 2.16049
25 2ZFI ADP 2.18579
26 4TQK NAG 2.21675
27 4P4T GDP 2.22222
28 4R43 GDP 2.35849
29 3RC3 ANP 2.35849
30 5H4S RAM 2.46479
31 4BFW ZVW 2.51572
32 2XTZ GSP 2.54237
33 1FNN ADP 2.57069
34 1H65 GDP 2.59259
35 5Y6N ADP 2.59434
36 5WS9 OXL 2.59434
37 5EVY SAL 2.59434
38 2CWH PYC 2.62391
39 5KSP GDP 2.63158
40 4WOP CTP 2.66667
41 4GBM A3P 2.78638
42 1NN5 2DT 2.7907
43 1NN5 ANP 2.7907
44 1YZG GDP 2.7933
45 4AG5 ADP 2.80612
46 6BSX GDP 2.80899
47 6BSX E7S 2.80899
48 2JLR ANP 2.83019
49 6C90 ADP 2.83019
50 4ZDJ UTP 2.83019
51 1PUJ GNP 2.83688
52 5L3W GDP 2.94118
53 6BYF CIT 2.94118
54 3COB ADP 2.98103
55 1O3Y GTP 3.01205
56 3B7G ANP 3.04348
57 5BN3 ADP 3.06604
58 5MZN ADP 3.06604
59 4ZG4 VO4 ADP 3.06604
60 4IDN GNP 3.06604
61 2FSH ANP 3.06604
62 6DEF GCP 3.06905
63 5EXT ADP 3.07692
64 4TO8 FLC 3.08219
65 1TAD ALF 3.08642
66 1TAD GDP 3.08642
67 3FYH ADP 3.10559
68 5EP2 AZU 3.125
69 1RE0 GDP 3.16742
70 6AU6 GDP 3.18302
71 1SVM ATP 3.18302
72 2C78 GNP 3.20988
73 2C77 GNP 3.20988
74 3AB3 GDP 3.25203
75 3T5G GDP 3.28947
76 1G41 ADP 3.30189
77 4NE2 SH2 3.30189
78 4NE2 ADP 3.30189
79 1X6V ADP 3.30189
80 4B47 GDP 3.30579
81 2BVN GNP 3.30789
82 1D8T GDP 3.30789
83 1WF3 GNP 3.32226
84 2OG2 MLI 3.34262
85 2I4I AMP 3.35731
86 2WIC GNP 3.37079
87 2WOJ ADP ALF 3.38983
88 3ZS9 ADP ALF 3.38983
89 1GWN GTP 3.41463
90 2ORV 4TA 3.4188
91 2ZR9 DTP 3.4384
92 1S9D GDP 3.44828
93 5CK5 GDP 3.48101
94 1D2E GDP 3.52645
95 1EK0 GNP 3.52941
96 4NCN GTP 3.53774
97 2GKS ADP 3.53774
98 4YS0 ADP 3.53774
99 4IEE AGS 3.53774
100 3HQP OXL 3.53774
101 2HCJ GDP 3.58209
102 2B8T THM 3.58744
103 3PQC GDP 3.58974
104 1XMV ADP 3.65169
105 5YVT NAI 3.67232
106 1W0J ADP 3.67647
107 1W0J ADP BEF 3.67647
108 1SVK ALF GDP 3.68272
109 4R98 GNH 3.69004
110 1NST A3P 3.69231
111 3QXC ATP 3.71901
112 1ZD9 GDP 3.7234
113 3SBD GNP 3.74332
114 2BME GNP 3.76344
115 5TSH ADP 3.77358
116 5TSH ANP 3.77358
117 1M2O GNP 3.77358
118 4DCT GDP 3.77358
119 1QHG ATP 3.77358
120 2ZPA ADP 3.77358
121 3ZQ6 ADP ALF 3.77358
122 2FAH GDP 3.77358
123 1YZN GNP 3.78378
124 2GDJ ANP 3.78788
125 1M7B GTP 3.80435
126 4LC1 GDP 3.85757
127 4FCW ADP 3.85852
128 5BYK A3P 3.861
129 5BYK OAQ 3.861
130 3A1S GDP 3.87597
131 2O0J ADP 3.8961
132 1V8K ANP 3.90244
133 3NHB ADP 3.92157
134 3TK1 GDP 3.93939
135 4M9Q GNP 3.96476
136 2GK6 ADP 4.00943
137 1YQT ADP 4.00943
138 5I0H ADP BEF 4.00943
139 4WZA ADP 4.00943
140 4WZA ACP 4.00943
141 5YV5 ADP 4.00943
142 1FP6 ADP 4.00943
143 1DAK ADP 4.01786
144 1DAK DPU 4.01786
145 2HT6 GDP 4.02299
146 5LB3 ADP 4.04494
147 4UTG ANP 4.04624
148 6G14 G4P 4.08163
149 3DKP ADP 4.08163
150 2J5V PCA 4.08719
151 3REF GDP 4.12371
152 1NY5 ADP 4.13437
153 4NU0 AP5 4.14747
154 4GOX A3P 4.15335
155 2CJW GDP 4.16667
156 3DEF GDP 4.19847
157 1Q19 SSC 4.24528
158 3BOF HCS 4.24528
159 2XTN GTP 4.2735
160 4R2I ANP 4.28571
161 1T5C ADP 4.29799
162 1W6F ISZ 4.31655
163 1RRC ADP 4.31894
164 5L3V GDP 4.34783
165 4TL6 ANP 4.34783
166 5UAV TFB 4.34783
167 5UAV NDP 4.34783
168 1TQ4 GDP 4.35835
169 5L3S GNP 4.36242
170 2V2V V12 4.42804
171 1RYH GNP 4.4335
172 5AK0 8V1 4.48113
173 1K6M AGS 4.48113
174 1XKV ATP 4.48113
175 5ZXD ATP 4.48113
176 2A2C NG1 4.48113
177 2A2C ADP 4.48113
178 1IN4 ADP 4.49102
179 4U5X GNP 4.49438
180 5NM7 GLY 4.51128
181 2G77 GDP 4.54545
182 1ZIN AP5 4.60829
183 4MKF AP5 4.60829
184 4MKG AP5 4.60829
185 1W5T ANP 4.61165
186 1W5T ADP 4.61165
187 4NON GDP 4.61538
188 1SVI GDP 4.61538
189 3W9F I3P 4.61538
190 3DC4 ADP 4.65116
191 1I4D GDP 4.6875
192 2C9O ADP 4.71698
193 2IS6 ADP 4.71698
194 2J0V GDP 4.71698
195 4PFO ADP 4.71698
196 1QF5 RPL 4.71698
197 1QF5 GDP 4.71698
198 1U8Z GDP 4.7619
199 3MD0 GDP 4.78873
200 4PX9 ADP 4.79452
201 2D2F ADP 4.8
202 6B8B ADP 4.81928
203 1MH1 GNP 4.83871
204 5Z69 AGS 4.83871
205 3ZFD ANP 4.8433
206 2BCG GDP 4.85437
207 2BCG GER 4.85437
208 1SQ5 ADP 4.87013
209 1G4U GDP 4.8913
210 3W5J GDP 4.90196
211 1VKJ A3P 4.91228
212 1OS1 ATP 4.95283
213 1OS1 PYR 4.95283
214 2XAU ADP 4.95283
215 2GCO GNP 4.97512
216 2GCN GDP 4.97512
217 1JI0 ATP 5
218 1JJ7 ADP 5
219 1Z0F GDP 5.02793
220 5ZB0 TYD 5.05051
221 5ZB0 ADP 5.05051
222 2FJU GSP 5.05618
223 1OXV ANP 5.09915
224 2ZE7 DST 5.13834
225 5TIV A3P 5.13834
226 2VVG ADP 5.14286
227 1G6O ADP 5.15152
228 2IXE ATP 5.16605
229 3BFV ADP 5.16605
230 5WXU FLC 5.18868
231 1G16 GDP 5.29412
232 3QKT ANP 5.30973
233 2WJG GDP 5.31915
234 4U00 ADP 5.32787
235 1YRB GDP 5.34351
236 1ZJ6 G3D 5.34759
237 5HCN GCP 5.36398
238 5IRC GDP 5.37634
239 3KDU NKS 5.41516
240 3CX8 GSP 5.41872
241 1SKQ GDP 5.42453
242 2BIF ANP 5.42453
243 2BIF SIN 5.42453
244 3TBK ANP 5.42453
245 1VBH PEP 5.42453
246 1KMQ GNP 5.43478
247 4UXH T5A 5.43478
248 1G6H ADP 5.44747
249 1WUU GLA 5.51378
250 4WZ6 ATP 5.51724
251 5N69 ADP 5.52764
252 3FB4 AP5 5.55556
253 5ZBR ANP 5.6
254 1X1R GDP 5.61798
255 1U0J ADP 5.61798
256 3B9Q MLI 5.62914
257 1W4R TTP 5.64103
258 1TX4 ALF GDP 5.64972
259 1Z6T ADP 5.66038
260 2GMV UN8 5.66038
261 2GMV PEP 5.66038
262 1NHX FTB 5.66038
263 1NHX PEP 5.66038
264 4IOK ADP 5.66038
265 4IOK XPO 5.66038
266 5XC5 GTP 5.68182
267 5E5U MLI 5.68182
268 1M7G ADP 5.6872
269 1M7G ADX 5.6872
270 1M7G AV2 5.6872
271 1DS6 GDP 5.72917
272 2HF9 GSP 5.75221
273 6CRK GDP 5.7971
274 1JJV ATP 5.82524
275 1UPT GTP 5.84795
276 4IHQ ADP 5.84795
277 4K81 GTP 5.84795
278 1GP2 GDP 5.88235
279 1G7S GDP 5.89226
280 2WHX ADP 5.89623
281 1P72 ADP 5.89623
282 1YTM ATP 5.89623
283 4D0N GDP 5.89812
284 1GOJ ADP 5.91549
285 1HE1 GDP 5.92593
286 2ZJ5 ADP 5.97222
287 5WLB GNP 6.0241
288 2WJH GDP 6.0241
289 2WJH FLC 6.0241
290 2Y65 ADP 6.0274
291 1R4A GNP 6.06061
292 1MR3 G3D 6.07735
293 2XT3 ADP 6.10465
294 5FG3 GDP 6.13208
295 1BG2 ADP 6.15385
296 2F3R G5P 6.28019
297 1OIX GDP 6.28272
298 1OIV GDP 6.28272
299 3KJI ADP 6.29921
300 1OFH ADP 6.32184
301 1F9V ADP 6.34006
302 3ZOK GLY 6.36792
303 3FWY ADP 6.36943
304 5GVR LMR 6.41026
305 1S3G AP5 6.45161
306 2W2X GSP 6.45161
307 2X7I CIT 6.49351
308 2QQ0 ANP 6.52174
309 2QQ0 THM 6.52174
310 2QQ0 TMP 6.52174
311 2QQ0 ADP 6.52174
312 2Q2Y ADP 6.53951
313 2Q2Y MKR 6.53951
314 6CS8 F9Y 6.60066
315 5WRJ A3P 6.60066
316 1MKY GDP 6.60377
317 5UIV ADP 6.60793
318 1FZQ GDP 6.62983
319 3WXM GTP 6.64894
320 4YMU ATP 6.66667
321 3FVQ ATP 6.68524
322 2RCN GDP 6.70391
323 3E70 GDP 6.70732
324 2OFW ADX 6.73077
325 2RGX AP5 6.79612
326 1L2T ATP 6.80851
327 1RJ9 GCP 6.83962
328 2IYL GDP 6.83962
329 2QEN ADP 6.85714
330 1NRJ GTP 6.88073
331 1UKZ ADP 6.89655
332 5G5G MCN 6.91824
333 3A4M ADP 6.92308
334 3TMK T5A 6.94444
335 2GJ8 ALF GDP 6.97674
336 5L3R GCP 6.97674
337 3IUY AMP 7.01754
338 1NF3 GNP 7.03125
339 2ZEJ GDP 7.06522
340 1KK1 GNP 7.07317
341 1CS4 GSP 7.07547
342 1QO8 FAD 7.07547
343 2CHG ANP 7.07965
344 1YVD GNP 7.10059
345 2C3H GLC GLC 7.14286
346 3Q72 GNP 7.22892
347 3P4X ADP 7.26392
348 2A5F GTP 7.31132
349 6B4K ANP 7.31132
350 2JAQ DCP 7.31707
351 2BEK ATP 7.393
352 1CR1 TTP 7.43243
353 1H74 ADP 7.43243
354 2F9L GDP 7.53769
355 1Z06 GNP 7.54717
356 1LVK MNT BEF 7.54717
357 1IHU AF3 7.54717
358 1IHU ADP 7.54717
359 2AWN ADP 7.61155
360 1B7T ADP 7.69231
361 5HPY GDP 7.75862
362 1KK8 BEF ADP 7.79221
363 3B5J 12D 7.81893
364 1ION ADP 7.81893
365 2PEZ DAT 7.82123
366 2PEZ GGZ 7.82123
367 3BOS CDP 7.85124
368 1OW3 GDP 7.85124
369 3DZD ADP 7.88043
370 1E96 GTP 7.88177
371 6AIC AMP 7.94393
372 1CEB AMH 7.95455
373 1DAR GDP 8.01887
374 1XP8 AGS 8.01887
375 2QG6 NMN 8.0402
376 2A9K GDP 8.07175
377 3RWO GDP 8.10811
378 2CK3 ANP 8.21918
379 2V7Q ATP 8.21918
380 2CK3 ADP 8.21918
381 2V7Q ADP 8.21918
382 1R2Q GNP 8.23529
383 1QF9 ADP 8.24742
384 1QF9 ALF 8.24742
385 1QF9 C5P 8.24742
386 4LPS GDP 8.26446
387 5O74 GDP 8.33333
388 3BER AMP 8.43373
389 3ZIA ATP 8.49057
390 4PJ3 ANP 8.49057
391 3ZIA ADP 8.49057
392 1KSH GDP 8.60215
393 1Z0K GTP 8.69565
394 3MJH GTP 8.82353
395 3VPD CIT 8.8968
396 1Z2A GDP 8.92857
397 3RLF ANP 8.94737
398 2VWT PYR 8.96226
399 4BAS GNP 9.04523
400 3T1O GDP 9.09091
401 4XVU ATP 9.13043
402 4XTR ATP 9.13043
403 4XTR ADP 9.13043
404 2RGO FAD 9.19811
405 1XX6 ADP 9.42408
406 1E2K TMC 9.43396
407 3IIJ ADP 9.44444
408 4ZNL BEF ADP 9.48905
409 1FQK GDP 9.52381
410 1B0U ATP 9.54198
411 5X40 ACP 9.58904
412 1LVG ADP 9.59596
413 1NJF ADP 9.6
414 1NJF AGS 9.6
415 1S8F GDP 9.60452
416 5UWH GNP 9.70464
417 5DHF GNP 9.70464
418 5UWP GNP 9.70464
419 6CIT GNP 9.70464
420 5UWW GNP 9.70464
421 5DIF GNP 9.70464
422 5UWO GNP 9.70464
423 5UWS GNP 9.70464
424 5UWU GNP 9.70464
425 5UWQ GNP 9.70464
426 5UWI GNP 9.70464
427 5UWR GNP 9.70464
428 5UWT GNP 9.70464
429 5UWJ GNP 9.70464
430 5DI9 GNP 9.70464
431 3BC1 GNP 9.74359
432 4TMK T5A 9.85915
433 2A5J GDP 9.94764
434 1Z08 GNP 10
435 4QRH 0O2 10
436 3RAB GNP 10.0592
437 1Z0J GTP 10.1695
438 4TTQ ATP 10.2326
439 5TB5 GDP 10.2703
440 5TAR GDP 10.2703
441 1UJ2 C5P 10.3175
442 1UJ2 ADP 10.3175
443 3GJ8 GDP 10.4072
444 3GJ7 GDP 10.4072
445 3GJ3 GDP 10.4072
446 3GJ0 GDP 10.4072
447 1CXZ GSP 10.4651
448 2UZI GTP 10.5769
449 1W7J ADP BEF 10.596
450 1VG8 GNP 10.628
451 1VG0 GDP 10.628
452 5BXQ GDP 10.6481
453 4HAT GNP 10.6481
454 1IBR GNP 10.6481
455 1KAO GDP 10.7784
456 4DID GDP 10.8808
457 3QBT GNP 10.9195
458 1G3Q ADP 10.9705
459 6FA4 GNP 10.9827
460 1GXU 2HP 10.989
461 1A4R GDP 10.9948
462 1A4R GNH 10.9948
463 2NGR GDP 10.9948
464 1GRN GDP 10.9948
465 4ITR GDP 10.9948
466 5XKT GNP 11
467 4HSE ADP 11.335
468 1LFD GNP 11.3772
469 6D56 GNP 11.3772
470 6D55 GNP 11.3772
471 6D59 GNP 11.3772
472 6D5J GNP 11.3772
473 6BVK GNP 11.3772
474 6D5E GNP 11.3772
475 6BVJ GNP 11.3772
476 6D5L GNP 11.3772
477 6D5H GNP 11.3772
478 6D5G GNP 11.3772
479 6BVL GNP 11.3772
480 6BVI GNP 11.3772
481 6D5V GNP 11.3772
482 6BVM GNP 11.3772
483 6D5M GNP 11.3772
484 1TU3 GNP 11.3924
485 3DDC GNP 11.4458
486 1WQ1 GDP 11.4458
487 1NVV GNP 11.4458
488 3CH5 GDP 11.5385
489 4HI0 GDP 11.5578
490 5UQW GDP 11.6402
491 5OCG GNP 11.6402
492 3GJ5 GDP 11.7647
493 1R6B ADP 11.7925
494 3H4S ADP 11.7925
495 4FRZ ADP 11.7925
496 2V5K OXM 11.7925
497 3Q85 GNP 11.8343
498 2PL3 ADP 11.8644
499 1VG1 GDP 11.8919
500 1VG9 GDP 11.8919
501 2D7C GTP 11.9048
502 4HDO GNP 11.976
503 1Z0A GDP 12.069
504 1F2U ATP 12.1622
505 4LJ9 ACP 12.2642
506 3M1I GTP 12.3288
507 4V0K GDP 12.426
508 2CDN ADP 12.4378
509 5Z2M GTP 12.5
510 3T12 GDP ALF 12.5
511 4Q1A 2XZ 12.5
512 4Q1A UDP 12.5
513 2C5L GTP 12.8205
514 5O2T GSP 13.0178
515 4OI4 ATP 13.0435
516 1WA5 GTP 13.0682
517 1XEX ATP 13.1868
518 3KTA AP5 13.1868
519 3QVV A3P 13.2203
520 4KFU ACP 13.6792
521 1KY3 GDP 13.7363
522 5BQ5 ADP BEF 13.7566
523 1CLU DBG 13.8554
524 2KIN ADP 14
525 2FFQ GSP 14.0351
526 2HV8 GTP 14.0625
527 2VB6 ADP BEF 14.094
528 1YZQ GNP 14.1176
529 1D5C GDP 14.1975
530 5U32 GDP 14.4068
531 2CE7 ADP 14.6226
532 1VHT BA3 14.6789
533 1D2N ANP 14.7059
534 2FH5 GTP 14.9533
535 1Z83 AP5 15.3061
536 2ODE ALF GDP 15.7143
537 4H1V GNP 15.7182
538 4QOS ADP 15.8491
539 4X8O AP5 15.8879
540 2QN6 GDP 16.129
541 1AKY AP5 16.3636
542 1FQJ GDP 16.6667
543 1KO8 6PG 17.1429
544 2W58 ADP 17.3267
545 2YOH WMJ 17.4528
546 1ZC3 GNP 17.7143
547 3GJ4 GDP 18.1818
548 4CVN ADP 18.9781
549 3HU3 AGS 19.1038
550 1F6B GDP 19.1919
551 4BQS ADP 19.3182
552 4BQS K2Q 19.3182
553 1GUA GNP 19.7531
554 3KUD GDP 19.7531
555 5HR5 ADP 19.8113
556 3QF7 ANP 20
557 4C4P GNP 20.5607
558 5UPK GNP 20.8333
559 1ZUI SKM 22.0238
560 3H86 AP5 22.3958
561 2QTV GNP 22.449
562 1QHH ATP 22.7545
563 5KDO GDP 22.973
564 1GOT GDP 23.2877
565 3UIE ANP 24.5
566 4D81 ADP 26.1484
567 2QZ4 ADP 26.3359
568 1J2J GTP 26.6667
569 2OM2 GDP 27.7778
570 2D7D ADP 35
Pocket No.: 2; Query (leader) PDB : 4XGU; Ligand: ADP; Similar sites found with APoc: 20
This union binding pocket(no: 2) in the query (biounit: 4xgu.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 3Q9T FAY 1.41509
2 2H5Z CTO 1.63934
3 3KLL MAL 2.12264
4 5FJJ MAN 2.35849
5 5AE2 FAD 2.35849
6 1IZC PYR 2.94985
7 3FC4 EDO 3.06604
8 2JBH 5GP 3.55556
9 3MWL 8OX 3.86473
10 1Q8A HCS 4.00943
11 1IWE IMP 4.00943
12 1T8U UAP SGN IDS SGN 4.41176
13 3ITJ CIT 4.73373
14 2XHK AKG 4.95496
15 2VHJ ADP 5.74018
16 1RL4 BRR 6.38298
17 5HTX ADP 8.72641
18 4B5W PYR 11.7925
19 3LL5 IP8 14.4578
20 4J56 FAD 14.9123
Pocket No.: 3; Query (leader) PDB : 4XGU; Ligand: ADP; Similar sites found with APoc: 2
This union binding pocket(no: 3) in the query (biounit: 4xgu.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 4U8P UDP 2.59434
2 1T3D CYS 5.19031
Pocket No.: 4; Query (leader) PDB : 4XGU; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4xgu.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4XGU; Ligand: ADP; Similar sites found with APoc: 3
This union binding pocket(no: 5) in the query (biounit: 4xgu.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 1JPA ANP 4.16667
2 3UN3 G16 4.7619
3 3FIU POP 4.81928
Pocket No.: 6; Query (leader) PDB : 4XGU; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4xgu.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback