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Receptor
PDB id Resolution Class Description Source Keywords
4X7L 1.9 Å EC: 2.7.11.1 CO-CRYSTAL STRUCTURE OF PERK BOUND TO 4-{2-AMINO-4-METHYL-3- (METHYLAMINO)-1,3-BENZOTHIAZOL-6-YL]BENZOYL}-1-METHYL-2,5-D2 -DIHYDRO-3H-PYRAZOL-3-ONE INHIBITOR HOMO SAPIENS CATALYTIC DOMAIN TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF 1H-PYRAZOL-3(2H)-ONES AS POTENT AND SE INHIBITORS OF PROTEIN KINASE R-LIKE ENDOPLASMIC RET KINASE (PERK). J.MED.CHEM. V. 58 1426 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
TLA A:1102;
Invalid;
none;
submit data
150.087 C4 H6 O6 [C@@H...
3Z4 A:1101;
Valid;
none;
ic50 = 9 nM
545.654 C32 H27 N5 O2 S Cc1cc...
GOL A:1103;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4G31 2.28 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF GSK6414 BOUND TO PERK (R587-R1092, DELE T867) AT 2.28 A RESOLUTION HOMO SAPIENS DELETION MUTANT CATALYTIC DOMAIN SYNTHETIC INHIBITOR TRANTRANSFERASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF 7-METHYL-5-(1-{[3-(TRIFLUOROMETHYL)PHENYL]ACETYL}-2 3-DIHYDRO-1H-INDOL-5-YL)-7H-PYRROLO[2,3-D]PYRIMIDIN (GSK2606414), A POTENT AND SELECTIVE FIRST-IN-CLASS INHIBITOR OF PROTEIN KINASE R (PKR)-LIKE ENDOPLASMI RETICULUM KINASE (PERK). J.ME
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 4G31 ic50 = 0.4 nM 0WH C24 H20 F3 N5 O Cn1cc(c2c1....
2 4X7H - 3Z2 C32 H26 N6 O5 CN1C(=C(C(....
3 4X7J ic50 = 41 nM 3Z1 C25 H22 F3 N5 O2 Cc1ccc(c(c....
4 4X7K ic50 = 4 nM 3Z3 C33 H27 F N6 O2 Cc1ccc(c(c....
5 4X7L ic50 = 9 nM 3Z4 C32 H27 N5 O2 S Cc1ccc(c(c....
6 4X7N ic50 = 6 nM 3Z5 C34 H28 N4 O2 Cc1ccc(c(c....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 4G31 ic50 = 0.4 nM 0WH C24 H20 F3 N5 O Cn1cc(c2c1....
2 4X7H - 3Z2 C32 H26 N6 O5 CN1C(=C(C(....
3 4X7J ic50 = 41 nM 3Z1 C25 H22 F3 N5 O2 Cc1ccc(c(c....
4 4X7K ic50 = 4 nM 3Z3 C33 H27 F N6 O2 Cc1ccc(c(c....
5 4X7L ic50 = 9 nM 3Z4 C32 H27 N5 O2 S Cc1ccc(c(c....
6 4X7N ic50 = 6 nM 3Z5 C34 H28 N4 O2 Cc1ccc(c(c....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 4G31 ic50 = 0.4 nM 0WH C24 H20 F3 N5 O Cn1cc(c2c1....
2 4X7H - 3Z2 C32 H26 N6 O5 CN1C(=C(C(....
3 4X7J ic50 = 41 nM 3Z1 C25 H22 F3 N5 O2 Cc1ccc(c(c....
4 4X7K ic50 = 4 nM 3Z3 C33 H27 F N6 O2 Cc1ccc(c(c....
5 4X7L ic50 = 9 nM 3Z4 C32 H27 N5 O2 S Cc1ccc(c(c....
6 4X7N ic50 = 6 nM 3Z5 C34 H28 N4 O2 Cc1ccc(c(c....
7 1ZY5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 3Z4; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 3Z4 1 1
2 3Z5 0.626168 0.854839
3 3Z3 0.538462 0.850746
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4G31; Ligand: 0WH; Similar sites found with APoc: 574
This union binding pocket(no: 1) in the query (biounit: 4g31.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 4K55 H6P None
2 4WG0 CHD None
3 3IWD M2T None
4 1FMB HYB None
5 3T50 FMN None
6 3KPE TM3 None
7 1N9L FMN None
8 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU None
9 2Z77 NCA None
10 4IBF 1D5 None
11 1F9V ADP 1.33779
12 5YJS SAL 1.33779
13 3ORQ ADP 1.33779
14 1GQG DCD 1.33779
15 4OFG PCG 1.38889
16 5SVV FMN 1.45985
17 4CNO 9PY 1.5873
18 2QK4 ATP 1.67224
19 4R78 AMP 1.67224
20 3WVR AMP 1.67224
21 5VRH PLM 1.67224
22 2IO8 ADP 1.67224
23 1KPG 16A 1.74216
24 5J75 6GQ 1.89394
25 5I0U DCY 2
26 4RDL FUC GAL NDG FUC 2.00669
27 1I7L ATP 2.00669
28 3OPT AKG 2.00669
29 3TII ANP 2.00669
30 4AVB CMP 2.00669
31 1HFE CYS 2.00669
32 3K5I ADP 2.00669
33 2GQR ADP 2.1097
34 2BHW NEX 2.15517
35 5NLD LBT 2.15827
36 5DNU KKN 2.18182
37 3EW2 BTN 2.22222
38 4DE3 DN8 2.28137
39 1M2Z BOG 2.33463
40 5ZCT ANP 2.34114
41 5VZ0 ADP 2.34114
42 5MW8 ATP 2.34114
43 5FPN KYD 2.34114
44 5G48 1FL 2.34114
45 2YRX AMP 2.34114
46 1GSA ADP 2.34114
47 5EQY 5RA 2.34114
48 4LHD GLY 2.34114
49 3VSV XYS 2.34114
50 1RYD GLC 2.34114
51 3ACL 3F1 2.36486
52 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.38095
53 5AIG VPR 2.4
54 3OF1 CMP 2.43902
55 1GVF PGH 2.44755
56 3VPC ADP 2.48227
57 3VPB ADP 2.48227
58 5OCG 9R5 2.6455
59 2IF8 ADP 2.67559
60 4GYI ADP 2.67559
61 5KJW 53C 2.67559
62 1M0W ANP 2.67559
63 5X7Q GLC GLC GLC GLC GLC 2.67559
64 2WKQ FMN 2.67559
65 1TV5 N8E 2.67559
66 5X7Q GLC GLC GLC GLC 2.67559
67 4MOB ADP 2.67559
68 1XL8 152 2.67559
69 4BG4 ADP 2.67559
70 3H4L ANP 2.67559
71 3QH2 3NM 2.71493
72 3THR C2F 2.73038
73 4OJ8 AKG 2.73038
74 3BP1 GUN 2.75862
75 2RDE C2E 2.78884
76 4TV1 36M 2.78884
77 4R38 RBF 2.85714
78 6FA4 D1W 2.89017
79 6GNO XDI 2.96296
80 3PCJ INO 3
81 3VOT ADP 3.01003
82 1ELI PYC 3.01003
83 2OZ5 7XY 3.01003
84 1A05 IPM 3.01003
85 3CBC DBS 3.0303
86 3P7N FMN 3.10078
87 1Y9Q MED 3.125
88 5V3Y 5V8 3.14685
89 1NE6 SP1 3.18021
90 5DYO FLU 3.21101
91 1R6N 434 3.31754
92 1TIQ COA 3.33333
93 5OSW DIU 3.34448
94 5L2R MLA 3.34448
95 3H0L ADP 3.34448
96 4GLW 0XT 3.34448
97 2TOH HBI 3.34448
98 5XOY LYS 3.34448
99 3WV6 GAL GLC 3.37838
100 5NFB 8VT 3.40909
101 5X3R 7Y3 3.41463
102 6B2M COA 3.4965
103 1QKQ MAN 3.52113
104 4D06 NAR 3.53357
105 4OIT MAN 3.53982
106 1IUP ALQ 3.5461
107 5ACM MBT 3.6036
108 6C74 PC 3.6036
109 3EHH ADP 3.66972
110 5C9P FUC 3.67454
111 5OES ADP 3.67893
112 4PZ6 GMP 3.67893
113 4YVN EBS 3.67893
114 4CC6 L5Y 3.67893
115 2BMB PMM 3.67893
116 4LIT AKG 3.67893
117 5B25 4QJ 3.67893
118 1YKD CMP 3.67893
119 1S5O 152 3.67893
120 5WZE PRO 3.67893
121 3IX9 MTX 3.68421
122 1GT4 UNA 3.77358
123 3CT5 NAG NAG NAG 3.77358
124 5H9P TD2 3.79747
125 4NFE BEN 3.79747
126 4WGF HX2 3.90244
127 3X01 AMP 4.01338
128 5DZT AMP 4.01338
129 3I0O ADP 4.01338
130 2BCG GER 4.01338
131 4GCZ FMN 4.01338
132 3JQ3 ADP 4.01338
133 3E3U NVC 4.06091
134 3AQT RCO 4.08163
135 4ZSI 4R1 4.09357
136 1NQ7 ARL 4.09836
137 2D5X L35 4.10959
138 4CNE SAH 4.11985
139 6E8I PTR 4.14201
140 4N9I PCG 4.28571
141 5L7G LYS SER LEU LEU GLN GLN LEU LEU THR GLU 4.34783
142 1P6O HPY 4.34783
143 2R0D 4IP 4.34783
144 2YW2 ATP 4.34783
145 5FPX GLY SER SER HIS HIS HIS HIS HIS 4.42478
146 2AK3 AMP 4.42478
147 1C9K 5GP 4.44444
148 4U0W 16G 4.47154
149 3PNA CMP 4.54545
150 2BKK ADP 4.54545
151 1HG4 LPP 4.6595
152 3W54 RNB 4.68227
153 4CS9 AMP 4.7619
154 5Y4R C2E 4.82759
155 5V4R MGT 4.93827
156 5HCN DAO 4.98084
157 5YK1 ANP 5.01672
158 4DFU QUE 5.01672
159 1RJW ETF 5.01672
160 4P25 FUC GAL NAG FUC 5.01672
161 3E70 GDP 5.01672
162 6GVZ CHO 5.01672
163 3G3N TC8 5.01672
164 2O1V ADP 5.01672
165 2R09 4IP 5.01672
166 4Y2B EPK 5.01672
167 3A76 SPD 5.11364
168 3T4L ZEA 5.18518
169 3ZJX BOG 5.19031
170 5XEG AKG 5.19481
171 6AP8 BNY 5.20446
172 2P7Q GG6 5.26316
173 5LX9 OLB 5.28169
174 3RGA LSB 5.30035
175 1NF8 BOG 5.31401
176 2XEM SSV 5.33333
177 6BU0 IHP 5.34351
178 4RF7 ARG 5.35117
179 2Z49 AMG 5.35117
180 2PYW ADP 5.35117
181 2Z48 NGA 5.35117
182 5C1P ADP 5.35117
183 2Z48 A2G 5.35117
184 2CFM AMP 5.35117
185 4RD0 GDP 5.35117
186 4OCV ANP 5.35117
187 3TDV GDP 5.35117
188 1I1E DM2 5.35117
189 5AHS COA 5.35117
190 2WPW ACO 5.35117
191 5AHS SIN 5.35117
192 1EYE PMM 5.35714
193 2VQZ MGT 5.42169
194 2V0U FMN 5.47945
195 3KDM TES 5.50459
196 5DKK FMN 5.51724
197 5DJT FMN 5.51724
198 5DJU FMN 5.51724
199 6BR8 6OU 5.55556
200 6BR8 PGV 5.55556
201 5CIC 51R 5.55556
202 3M3E GAL A2G NPO 5.59006
203 2DTJ THR 5.61798
204 3FAL REA 5.6391
205 5W10 CMP 5.64103
206 4CYI ATP 5.68562
207 5I35 ANP 5.68562
208 5O9W AKG 5.68562
209 3QSB 743 5.68562
210 5XVH TLA 5.68562
211 5F6U 5VK 5.73248
212 4ZS4 ATP 5.86319
213 6AP6 TLF 5.94796
214 1SLT NDG GAL 5.97015
215 4XMF HSM 5.97826
216 5BU3 4W9 5.97826
217 5KJZ PCG 6
218 2PUL ACP 6.02007
219 3I8T LBT 6.09756
220 2ZL7 FUC GAL NGA 6.1017
221 6GBV FMN 6.16438
222 5IM3 DTP 6.35452
223 5E58 CPZ 6.35452
224 4WCX MET 6.35452
225 3HYW DCQ 6.35452
226 2NV2 GLN 6.37255
227 2GWH PCI 6.37584
228 1TQP ATP 6.38298
229 3VPD ANP 6.40569
230 6FS0 E4W 6.51163
231 2ALG DAO 6.52174
232 5VLQ ANP 6.68896
233 4OUJ LBT 6.68896
234 2Z3U CRR 6.68896
235 1WDK N8E 6.68896
236 3UG4 AHR 6.68896
237 4XJ7 ADE 6.74157
238 1XMY ROL 6.78392
239 1XM4 PIL 6.78392
240 4UCC ZKW 6.86695
241 2ZMF CMP 6.87831
242 5HWV MBN 6.92308
243 4V1F BQ1 6.97674
244 5C8W PCG 6.99301
245 5VNF VAL THR SER VAL VAL 7.00637
246 1VRP ADP 7.02341
247 4UWH JXM 7.02341
248 4G86 BNT 7.04225
249 5FS0 5JC 7.109
250 3NV3 GAL NAG MAN 7.24638
251 5OO5 UUA 7.25806
252 5USZ SKE 7.26644
253 5MTE BB2 7.29927
254 3R9V DXC 7.34266
255 3HAV ATP 7.35786
256 2P5B OGA 7.35786
257 6EOM ALA LYS 7.35786
258 4HIA FMN 7.38636
259 2PR5 FMN 7.57576
260 5OF1 SAL 7.61905
261 1TZD ADP 7.63636
262 1DZK PRZ 7.64331
263 2XHK AKG 7.65766
264 5HV7 RBL 7.69231
265 2WR1 NAG 7.69231
266 1AUX AGS 7.69231
267 3T1A 5MA 7.69231
268 1PK8 ATP 7.69231
269 4QAC KK3 7.8341
270 1IA9 ANP 7.85714
271 4F4S EFO 7.89474
272 3KP6 SAL 7.94702
273 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 7.94979
274 1ULE GLA GAL NAG 8
275 2WOR 2AN 8
276 5GZ9 ANP 8.02676
277 3SQP 3J8 8.02676
278 1C1L GAL BGC 8.0292
279 3WUD GLC GAL 8.08823
280 2QX0 PH2 8.1761
281 1A78 TDG 8.20895
282 1W2D ADP 8.30189
283 1LSH PLD 8.3612
284 2VPQ ANP 8.3612
285 2WBV SIA 8.46561
286 1OW4 2AN 8.52713
287 4ONT SIA GAL BGC 8.52713
288 4WW7 AMP 8.55615
289 3ETH ATP 8.69565
290 1HBK MYR 8.98876
291 4AZW ATP 9.0301
292 5I8F ML1 9.09091
293 3G08 FEE 9.09091
294 5HV0 AKG 9.21659
295 1LNM DTX 9.23913
296 5Y02 HBX 9.34579
297 4OGQ 1O2 9.49721
298 4OGQ 7PH 9.49721
299 3TDC 0EU 9.699
300 5LUN OGA 9.699
301 5GLT BGC GAL NAG GAL 9.85915
302 2G30 ALA ALA PHE 10.0775
303 4C5N ACP 10.1449
304 4WUJ FMN 10.2041
305 5ZQ4 AMP 10.2564
306 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 10.4348
307 4Q5H ANP 10.5263
308 3SJK LYS PRO VAL LEU ARG THR ALA 10.5263
309 1DTL BEP 10.559
310 5TFZ 7BC 10.6667
311 3AB4 THR 10.6742
312 1N5S ADL 10.7143
313 4RYV ZEA 10.9677
314 5T7I LAT NAG GAL 10.9677
315 6DZN AE3 11.0619
316 3KMW ATP 11.0701
317 3T03 3T0 11.1111
318 1ZTH ADP 11.2403
319 1ZP9 ATP 11.2403
320 2PRG BRL 11.3636
321 1QMG DMV 11.3712
322 4IX4 ADP 11.7057
323 4O1P ANP 12.0401
324 5VKM GAL SIA 12.0401
325 3PQB VGP 12.0401
326 2GTF P1R 12.2222
327 5H9Q TD2 12.2581
328 4JH6 FCN 12.3188
329 5LWY OLB 12.605
330 4OAV ACP 12.709
331 4WQ2 3SU 12.7168
332 6MJ7 ARG 12.7273
333 3EYK EYK 12.7907
334 2Y69 CHD 12.7907
335 3ER9 3AT 12.7946
336 4CNG SAH 12.9412
337 5N8V KZZ 13.0435
338 4OCT AKG 13.0631
339 4KU7 PCG 13.0719
340 4NPL AKG 13.2
341 3UDZ ADP 13.3779
342 1U6R ADP 13.3779
343 5B09 4MX 13.4615
344 4XZ3 ACP 13.4783
345 4XYM A12 13.4783
346 3JU6 ANP 13.7124
347 1QY1 PRZ 13.7931
348 5KEW 6SB 13.8298
349 5N0L ILE 13.8365
350 1I06 TZL 13.8889
351 4WOE ADP 14.0468
352 6GG9 FMN 14.1975
353 3ZXE PGZ 14.2857
354 1Y7P RIP 14.3498
355 1CBK ROI 14.375
356 6CS9 PIO 14.6341
357 1KJ1 MAN 14.6789
358 5OKT 9XK 14.7157
359 4KBA 1QM 14.7157
360 5JAX 6J7 14.8148
361 2OKL BB2 15.1351
362 2GC0 PAN 15.9574
363 1UYY BGC BGC 16.0305
364 5C03 AGS 16.0535
365 4WOV 3SM 16.0535
366 1N8V BDD 16.0714
367 5ZTN CUR 16.388
368 3G58 988 16.388
369 2WU6 DKI 17.0569
370 3SHR CMP 17.3913
371 5WNL STU 17.3913
372 5W97 CHD 17.4312
373 5ZCO CHD 17.4312
374 1UW1 ADP 17.5
375 3SAO DBH 18.125
376 3SAO NKN 18.125
377 5EFW FMN 18.3333
378 5MY8 RXZ 18.3946
379 5MWE TCE 18.5185
380 6FYL 3NG 19.0635
381 4CQK PIO 19.1489
382 5CKW ANP 20.4013
383 5KK4 44E 20.8333
384 5Y86 HRM 21.4047
385 3OYW TDG 21.6418
386 1W6P NDG GAL 21.6418
387 4BTK DTQ 23.7458
388 3VHE 42Q 25.0836
389 3LQV ADE 25.641
390 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 25.7143
391 4Y85 499 26.087
392 3GNI ATP 27.7592
393 6GWR FEW 29.097
394 2CSN CKI 29.2929
395 6ES0 BW8 29.4314
396 4FL3 ANP 30.4348
397 5EOB 5QQ 30.7692
398 5NKB 8ZT 31.1037
399 1VJY 460 31.1037
400 3BU5 ATP 31.1037
401 3C1X CKK 31.1037
402 1IR3 ANP 31.1037
403 1K3A ACP 31.4381
404 5LPZ ADP 31.4381
405 5LPB ADP 31.7568
406 3H9R TAK 31.7726
407 3EKK GS2 31.7726
408 2H8H H8H 31.7726
409 1Y57 MPZ 31.7726
410 6GIN IR2 32.107
411 3NW7 LGV 32.107
412 2OO8 RAJ 32.107
413 3LXK MI1 32.107
414 3KRL KRL 32.107
415 4YMJ 4EJ 32.107
416 4Y93 746 32.107
417 2Y6O 1N1 32.3024
418 5CEO 50D 32.4415
419 1JPA ANP 32.7759
420 6FYV 3NG 32.7759
421 1OPK P16 32.7759
422 6G33 5ID 32.7759
423 2XVD AS6 32.7759
424 5HES 032 32.7759
425 5MJA 7O3 32.7759
426 5X8I SQZ 32.7759
427 4E93 GUI 32.7759
428 2X2M X2M 32.7759
429 5LI1 ANP 32.7759
430 5LI9 ACP 32.7759
431 4DC2 ADE 32.7759
432 3G5D 1N1 32.8671
433 3PLS ANP 32.8859
434 5EFQ ADP 33.1104
435 3UIM ANP 33.1104
436 5WO4 B7V 33.1104
437 6GQM F8H 33.4448
438 4GJ3 0XP 33.4448
439 1OUK 084 33.4448
440 4LOO SB4 33.4448
441 3LXN MI1 33.4448
442 4E1Z 0MX 33.677
443 2F2U M77 33.7793
444 3E8N VRA 33.7793
445 3E8N ATP 33.7793
446 5HCY 60D 33.7793
447 3PP0 03Q 33.7793
448 6C0T EE4 33.7793
449 4UXL 5P8 33.7793
450 4H3P ANP 33.7793
451 4IDT T28 33.7793
452 5JKG 6LF 34.1137
453 4P5Z Q7M 34.1137
454 5BVE 4VG 34.1137
455 3RI1 3RH 34.1137
456 4NST ADP 34.1137
457 1U59 STU 34.1463
458 5T8O 76Z 34.384
459 2QLU ADE 34.4482
460 4H3Q ANP 34.4482
461 3PVW QRX 34.4482
462 5UKL SIX 34.4482
463 4OTH DRN 34.4482
464 6C7Y ADP 34.6154
465 5TO8 7FM 34.7518
466 4XH0 ADP 34.7826
467 3TXO 07U 34.7826
468 2B9H ADP 34.7826
469 5JFS 6K0 34.7826
470 2B9J ADP 34.7826
471 2B9I ADP 34.7826
472 5DBX ANP 35.1171
473 3VRY B43 35.1171
474 2B9F ADP 35.1171
475 5KO1 6UY 35.3357
476 1O9U ADZ 35.4515
477 3ALN ANP 35.4515
478 4QMN DB8 35.4515
479 4QTB 38Z 35.4515
480 3F7Z 34O 35.4515
481 3ZRM ZRM 35.4515
482 2F57 23D 35.4515
483 4NM5 ADP 35.4515
484 3SRV S19 35.7401
485 4UX9 ANP 35.786
486 4WHZ 3NL 35.786
487 1XJD STU 35.786
488 3PTG 932 35.786
489 3E7O 35F 36.1204
490 3TTI KBI 36.1204
491 2JLD AG1 36.1204
492 2QCS ANP 36.1204
493 5FBN 5WF 36.1624
494 4F4P 0SB 36.2637
495 4CRL C1I 36.4548
496 5HQ0 LZ9 36.4548
497 6GU6 1QK 36.4548
498 4WB6 ATP 36.4548
499 4WB7 ATP 36.4548
500 4FG8 ATP 36.4548
501 4RFM 3P6 36.4662
502 2GU8 796 36.7893
503 1RE8 BD2 36.7893
504 3IDB ANP 36.7893
505 3FHI ANP 36.7893
506 4TWP AXI 36.9004
507 4EWH T77 37.0909
508 4CLI 5P8 37.1237
509 4AT3 LTI 37.1237
510 1PHK ATP 37.2483
511 3IGO ANP 37.4582
512 5U6C 7YS 37.4582
513 5H2U 1N1 37.8277
514 2OFV 242 37.9061
515 4PNI KQQ 38.1271
516 4L9I 8PR 38.1271
517 1BYG STU 38.1295
518 6CZ3 FLJ 38.2576
519 3SXS PP2 38.4328
520 5N87 N66 38.4615
521 6A1G 9OL 38.4615
522 3HMO STU 38.796
523 2HK5 1BM 38.8889
524 2WEI VGG 39.0244
525 3BZ3 YAM 39.1304
526 4BCQ TJF 39.4649
527 6CMJ F6J 39.4649
528 4CFU 2WC 39.4649
529 6GUE FB8 39.4649
530 4BCN T9N 39.4649
531 4BCM T7Z 39.4649
532 6E2O S0L 39.661
533 5LMK 6ZK 39.7306
534 5AWM ANP 39.7993
535 2BPM 529 39.7993
536 2ZV2 609 39.7993
537 4BHN BH9 39.7993
538 2XMY CDK 39.9329
539 4AG8 AXI 40.1338
540 4ASE AV9 40.1338
541 2VN9 GVD 41.1371
542 2VZ6 FEF 41.1371
543 2WEL K88 41.1371
544 4U0I 0LI 41.4716
545 1CM8 ANP 41.4716
546 3GQI ACP 41.4716
547 1U5R ATP 41.806
548 5UR1 YY9 42.1405
549 2V7O DRN 42.1405
550 5EKO N17 42.1405
551 2PVF ACP 42.1405
552 3FC2 IBI 42.4749
553 5TA6 79D 42.4749
554 4WNK 453 42.4749
555 3HZT J60 43.1438
556 4K33 ACP 43.1438
557 5QIN J2V 43.1438
558 4YZC STU 43.8127
559 4IZY 1J2 43.8127
560 4ONA UW1 44.1472
561 3GC8 B45 44.1472
562 4AUA 4AU 44.4816
563 3SLS ANP 44.4816
564 3SLS 77D 44.4816
565 5EH0 5NW 44.5736
566 4CSV STI 44.7273
567 4I6H 1C8 44.8161
568 4AU8 Z3R 46.2838
569 3GC0 AMP 46.4883
570 5JGA 6KC 47.1572
571 3O0G 3O0 47.2603
572 1UNH IXM 47.2603
573 1V0O INR 48.2639
574 5VC5 96M 49.481
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