Receptor
PDB id Resolution Class Description Source Keywords
4WVV 1.21 Å NON-ENZYME: BINDING CHICKEN GALECTIN-8 N-TERMINAL DOMAIN COMPLEXED WITH LACTOSE GALLUS GALLUS LECTIN CARBOHYDRATE RECOGNITION DOMAIN SUGAR BINDING PROTE
Ref.: COMBINING CRYSTALLOGRAPHY AND HYDROGEN-DEUTERIUM EX STUDY GALECTIN-LIGAND COMPLEXES. CHEMISTRY V. 21 13558 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LBT A:201;
Valid;
none;
submit data
342.296 C12 H22 O11 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4WVW 1.47 Å NON-ENZYME: BINDING CHICKEN GALECTIN-8 N-TERMINAL DOMAIN COMPLEXED WITH 3'-SIALY GALLUS GALLUS LECTIN CARBOHYDRATE RECOGNITION DOMAIN SUGAR BINDING PROTE
Ref.: COMBINING CRYSTALLOGRAPHY AND HYDROGEN-DEUTERIUM EX STUDY GALECTIN-LIGAND COMPLEXES. CHEMISTRY V. 21 13558 2015
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 4WVV - LBT C12 H22 O11 C([C@@H]1[....
2 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
2 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
3 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
4 3VKO - SIA GAL NAG n/a n/a
5 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
6 5T7T Kd = 2.1 uM GAL NAG n/a n/a
7 4WVV - LBT C12 H22 O11 C([C@@H]1[....
8 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
50% Homology Family (94)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
13 4R9D - LAT C12 H22 O11 C([C@@H]1[....
14 1KJL Kd = 67 uM GAL NAG n/a n/a
15 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
16 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
17 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
18 4R9C - LAT C12 H22 O11 C([C@@H]1[....
19 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
20 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
21 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
22 3AYE - LAT C12 H22 O11 C([C@@H]1[....
23 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
24 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
25 2NMO Kd = 260 uM GAL BGC n/a n/a
26 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
27 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
28 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
29 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
30 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
31 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
32 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
33 2D6N - GAL NAG n/a n/a
34 2D6M - LBT C12 H22 O11 C([C@@H]1[....
35 2D6O - NAG GAL GAL NAG n/a n/a
36 4XBN Kd = 93 uM GAL NAG n/a n/a
37 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
38 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
39 5DG2 - GAL GLC n/a n/a
40 5EWS - GAL BGC n/a n/a
41 4XBL Kd = 340 uM GAL NAG n/a n/a
42 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
43 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
44 3OY8 Kd = 220 uM GAL GCO n/a n/a
45 2EAL - GAL NGA A2G n/a n/a
46 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
47 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
48 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
49 2ZHM - NAG GAL GAL NAG GAL n/a n/a
50 2EAK - LBT C12 H22 O11 C([C@@H]1[....
51 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
52 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
53 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
54 4XBQ Kd = 270 uM GAL NAG n/a n/a
55 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
56 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
57 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
58 3VKO - SIA GAL NAG n/a n/a
59 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
60 5T7T Kd = 2.1 uM GAL NAG n/a n/a
61 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
62 3WV6 - GAL BGC n/a n/a
63 3NV2 - GAL NDG n/a n/a
64 3NV4 - SIA GAL BGC n/a n/a
65 3NV3 - GAL NAG MAN n/a n/a
66 3WUD Kd = 41 uM GLC GAL n/a n/a
67 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
68 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
69 2GAL - GAL C6 H12 O6 C([C@@H]1[....
70 4GAL - GAL BGC n/a n/a
71 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
72 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
73 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
74 5GAL - NAG GAL n/a n/a
75 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
76 1GAN - NDG GAL n/a n/a
77 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
78 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
79 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
80 5DUX Kd = 380 uM LAT FUC n/a n/a
81 4WVV - LBT C12 H22 O11 C([C@@H]1[....
82 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
83 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
84 5CBL - LAT C12 H22 O11 C([C@@H]1[....
85 4YM2 Kd = 1400 uM SGA BGC n/a n/a
86 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
87 4YM1 Kd = 580 uM LAT FUC n/a n/a
88 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
89 1WLD - GAL BGC n/a n/a
90 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
91 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
92 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
93 1SLT - NDG GAL n/a n/a
94 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LBT; Similar ligands found: 339
No: Ligand ECFP6 Tc MDL keys Tc
1 LBT 1 1
2 GLC BGC 1 1
3 MAL MAL 1 0.970588
4 BGC GLC 1 1
5 CBI 1 1
6 GAL BGC 1 1
7 CBK 1 1
8 BGC BMA 1 1
9 N9S 1 1
10 GLA GLA 1 1
11 BGC GAL 1 1
12 GAL GLC 1 1
13 GLC GAL 1 1
14 BMA BMA 1 1
15 GLA GAL 1 1
16 BMA GAL 1 1
17 LAT 1 1
18 MAB 1 1
19 MAL 1 1
20 B2G 1 1
21 CEX 0.909091 1
22 BGC GLC GLC GLC GLC 0.909091 1
23 GLC GLC GLC GLC GLC 0.909091 1
24 CTR 0.909091 1
25 MTT 0.909091 1
26 CE5 0.909091 1
27 BMA BMA BMA BMA BMA 0.909091 1
28 CTT 0.909091 1
29 CT3 0.909091 1
30 GLC GLC GLC GLC GLC GLC GLC 0.909091 1
31 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
32 BGC BGC BGC GLC 0.909091 1
33 CEY 0.909091 1
34 MAN MAN BMA BMA BMA BMA 0.909091 1
35 BMA BMA BMA 0.909091 1
36 B4G 0.909091 1
37 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
38 GLC GAL GAL 0.909091 1
39 GLA GAL GLC 0.909091 1
40 GAL GAL GAL 0.909091 1
41 MAN BMA BMA BMA BMA 0.909091 1
42 MLR 0.909091 1
43 CE8 0.909091 1
44 MT7 0.909091 1
45 CE6 0.909091 1
46 GLC BGC BGC BGC BGC BGC 0.909091 1
47 GLC GLC BGC 0.909091 1
48 GLC BGC BGC 0.909091 1
49 GLC BGC GLC 0.909091 1
50 BMA MAN BMA 0.909091 1
51 GLC GLC BGC GLC GLC GLC GLC 0.909091 1
52 BGC GLC GLC 0.909091 1
53 BGC GLC GLC GLC 0.909091 1
54 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
55 DXI 0.909091 1
56 BMA BMA BMA BMA BMA BMA 0.909091 1
57 GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
58 GLC BGC BGC BGC BGC 0.909091 1
59 BGC BGC BGC BGC BGC BGC 0.909091 1
60 MAN BMA BMA 0.909091 1
61 MAN BMA BMA BMA BMA BMA 0.833333 0.970588
62 BMA BMA BMA BMA BMA BMA MAN 0.833333 0.970588
63 GLA GAL GAL 0.816327 1
64 GLA GAL BGC 0.816327 1
65 BGC BGC BGC BGC 0.754717 1
66 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
67 BMA BMA GLA BMA BMA 0.689655 1
68 LAT GLA 0.680851 1
69 GLC GLC GLC BGC 0.672414 1
70 BGC BGC GLC 0.660377 1
71 U63 0.647059 0.891892
72 DR5 0.64 0.942857
73 MMA MAN 0.64 0.942857
74 GLA EGA 0.634615 0.942857
75 BMA BMA MAN 0.615385 0.970588
76 GAL FUC 0.615385 0.941176
77 BGC BGC 0.612245 1
78 MAN MAN 0.612245 1
79 2M4 0.612245 1
80 GLC GAL FUC 0.610169 0.970588
81 GLC GLC GLC GLC GLC GLC 0.610169 1
82 FUC LAT 0.610169 0.970588
83 FUC GAL GLC 0.610169 0.970588
84 BGC GAL FUC 0.610169 0.970588
85 LAT FUC 0.610169 0.970588
86 BGC GLA GAL FUC 0.609375 0.970588
87 GAL NAG GAL BGC 0.606061 0.733333
88 LAT NAG GAL 0.606061 0.733333
89 GLC GLC BGC XYS BGC XYS 0.606061 0.942857
90 BGC GAL NAG GAL 0.606061 0.733333
91 MAN GLC 0.6 1
92 LB2 0.6 1
93 M3M 0.6 1
94 SGA BGC 0.6 0.702128
95 MAL EDO 0.592593 0.942857
96 BGC BGC BGC XYS GAL 0.588235 0.942857
97 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
98 GLC GAL NAG GAL 0.588235 0.733333
99 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
100 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
101 NGA GAL BGC 0.587302 0.733333
102 TRE 0.581395 1
103 ABD 0.57971 0.75
104 NDG GAL 0.578947 0.733333
105 GAL NDG 0.578947 0.733333
106 5GO 0.578947 0.66
107 NLC 0.578947 0.733333
108 DEL 0.574074 0.970588
109 GAL NGA GLA BGC GAL 0.571429 0.733333
110 MVP 0.571429 0.733333
111 GAL BGC BGC XYS 0.569231 0.942857
112 GLC GLC FRU 0.569231 0.868421
113 BMA MAN 0.566038 0.914286
114 GLC GLC XYP 0.557377 1
115 BGC BGC XYS BGC 0.552239 0.942857
116 NAG GAL BGC 0.552239 0.733333
117 GLA GAL BGC 5VQ 0.551724 0.891892
118 G2F BGC BGC BGC BGC BGC 0.55 0.868421
119 GLA MBG 0.54902 0.942857
120 GLC ACI GLD GLC 0.547945 0.785714
121 GLC G6D ACI GLC 0.547945 0.785714
122 GLC ACI G6D BGC 0.547945 0.785714
123 GLC G6D ADH GLC 0.547945 0.785714
124 GLC BGC BGC BGC 0.545455 1
125 BGC BGC BGC ASO BGC BGC ASO 0.545455 1
126 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
127 BGC BGC BGC 0.545455 1
128 BGC BGC BGC GLC BGC BGC 0.545455 1
129 BGC BGC BGC BGC BGC 0.545455 1
130 MAN MAN BMA 0.535714 1
131 NGA GLA GAL BGC 0.535211 0.733333
132 BMA MAN MAN 0.534483 1
133 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
134 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
135 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
136 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
137 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
138 GLA GAL GLC NBU 0.52459 0.846154
139 FUC BGC GAL 0.52459 0.970588
140 GLC ACI GLD GAL 0.519481 0.733333
141 GLC ACI G6D GLC 0.519481 0.733333
142 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.785714
143 GLC BGC BGC BGC XYS BGC XYS XYS 0.513514 0.916667
144 DOM 0.509091 0.942857
145 GAL GAL SO4 0.508197 0.702128
146 DMU 0.507937 0.785714
147 LMT 0.507937 0.785714
148 LMU 0.507937 0.785714
149 G2I 0.507937 0.767442
150 G3I 0.507937 0.767442
151 OXZ BGC BGC 0.507937 0.6875
152 UMQ 0.507937 0.785714
153 GLC AGL GLC HMC 0.506329 0.717391
154 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
155 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
156 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
157 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
158 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
159 NAG GAL GAL 0.5 0.733333
160 SOR GLC GLC 0.5 0.970588
161 GAL GAL GLC EMB MEC 0.5 0.622642
162 FMO 0.5 0.868421
163 MAN BMA NAG 0.5 0.733333
164 GLA GAL NAG 0.5 0.733333
165 8VZ 0.5 0.673469
166 GLC GLC ACI G6D GLC GLC 0.493827 0.733333
167 GLC GLC AGL HMC GLC 0.493827 0.733333
168 GLC GLC DAF BGC 0.493827 0.733333
169 AAO 0.493827 0.733333
170 ARE 0.493827 0.733333
171 ACR GLC GLC GLC 0.493827 0.733333
172 GLC GLC XYS 0.492308 0.970588
173 CGC 0.491525 0.941176
174 5QP 0.491228 0.885714
175 MDM 0.490909 0.942857
176 RZM 0.490909 0.688889
177 M13 0.490909 0.942857
178 GAL MBG 0.490909 0.942857
179 GLC GLC GLC G6D ADH GLC 0.487805 0.6875
180 BGC BGC G2F SHG 0.485714 0.846154
181 MAN NAG GAL 0.485294 0.733333
182 GAL NAG MAN 0.485294 0.733333
183 6UZ 0.484848 0.846154
184 SOR GLC GLC GLC 0.484848 0.970588
185 LAG 0.484848 0.6
186 MAN MNM 0.482759 0.75
187 GAL BGC NAG GAL 0.478873 0.733333
188 10M 0.477612 0.733333
189 GTM BGC BGC 0.477612 0.868421
190 MAN MAN MAN MAN 0.476923 1
191 MAN MAN BMA MAN 0.476923 1
192 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
193 NAG BMA 0.47619 0.653061
194 GAL NGA 0.47541 0.733333
195 GAL A2G 0.47541 0.733333
196 A2G GAL 0.47541 0.733333
197 BMA GLA 0.472727 1
198 LAK 0.472727 1
199 GAL GAL 0.472727 1
200 GLA GLC 0.472727 1
201 MLB 0.472727 1
202 GLA BMA 0.472727 1
203 BGC GLA 0.472727 1
204 MAN BMA 0.472727 1
205 GLA BGC 0.472727 1
206 NPJ 0.470588 0.622642
207 FUC GAL NAG GAL BGC 0.469136 0.717391
208 MAN MAN MAN GLC 0.46875 1
209 ABL 0.466667 0.702128
210 BMA FRU 0.465517 0.842105
211 FRU GAL 0.465517 0.842105
212 NOY BGC 0.465517 0.75
213 TM6 0.463768 0.916667
214 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
215 LSE 0.462687 0.6875
216 GLA GLA FUC 0.460317 0.970588
217 FUC GAL GLA 0.460317 0.970588
218 GAL GAL FUC 0.460317 0.970588
219 GLA GAL FUC 0.460317 0.970588
220 FUC GLA GLA 0.460317 0.970588
221 DAF BGC 0.458333 0.785714
222 DAF GLC 0.458333 0.785714
223 IFM BMA 0.457627 0.744186
224 BGC OXZ 0.457627 0.666667
225 IFM BGC 0.457627 0.744186
226 BMA IFM 0.457627 0.744186
227 9MR 0.457627 0.744186
228 GLO GLC GLC 0.457143 0.942857
229 RCB 0.457143 0.622642
230 GLC GLC GLC GLC GLC BGC 0.45614 1
231 GLC GLC GLC 0.45614 1
232 GLC GLC GLC GLC BGC 0.45614 1
233 MAN MAN MAN 0.45614 1
234 GLC 0.454545 0.848485
235 BMA 0.454545 0.848485
236 GXL 0.454545 0.848485
237 WOO 0.454545 0.848485
238 GIV 0.454545 0.848485
239 GAL 0.454545 0.848485
240 MAN 0.454545 0.848485
241 BGC 0.454545 0.848485
242 ALL 0.454545 0.848485
243 GLA 0.454545 0.848485
244 GLC GLC GLC GLC 0.453125 1
245 MGL SGC GLC GLC 0.450704 0.868421
246 CM5 0.450704 0.891892
247 MAN MAN MAN BMA MAN 0.450704 1
248 BGC BGC SGC MGL 0.450704 0.868421
249 GLC DMJ 0.45 0.727273
250 A2G GAL BGC FUC 0.45 0.717391
251 GLC GLC GLC PO4 SGC GLC 0.45 0.673469
252 NOJ GLC 0.45 0.727273
253 PA1 GCS 0.448276 0.804878
254 GCS GCS 0.448276 0.804878
255 M5S 0.447761 1
256 MAN BMA MAN MAN MAN 0.447761 1
257 GLC GLC XYS XYS 0.447761 0.914286
258 DAF BGC GLC 0.447368 0.785714
259 TXT 0.447368 0.767442
260 GAC 0.447368 0.767442
261 DAF GLC GLC 0.447368 0.785714
262 ACI GLD GLC GAL 0.447368 0.785714
263 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
264 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
265 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
266 NAG GAL GAL NAG GAL 0.445946 0.6875
267 NAG GAL GAL NAG 0.445946 0.6875
268 MA4 0.444444 0.891892
269 QV4 0.444444 0.733333
270 GLO GLC GLC GLC 0.444444 0.942857
271 MAN DGO 0.440678 0.914286
272 3SA 0.44 0.733333
273 Z6J 0.439024 0.742857
274 AHR 0.439024 0.742857
275 32O 0.439024 0.742857
276 FUB 0.439024 0.742857
277 RIB 0.439024 0.742857
278 T6P 0.438596 0.767442
279 GYP 0.4375 0.857143
280 AMG 0.4375 0.857143
281 MMA 0.4375 0.857143
282 MBG 0.4375 0.857143
283 4MU BGC BGC 0.434211 0.767442
284 ISX 0.433333 0.761905
285 MAN 7D1 0.431034 0.888889
286 QPS 0.43038 0.733333
287 ACR 0.43038 0.733333
288 4MU BGC BGC BGC BGC 0.428571 0.767442
289 GAL MGC 0.428571 0.702128
290 GAL NGA A2G 0.426471 0.673469
291 FUC NAG GAL 0.422535 0.717391
292 FUC NDG GAL 0.422535 0.717391
293 GAL NAG FUC 0.422535 0.717391
294 GAL NDG FUC 0.422535 0.717391
295 KHO 0.421053 0.888889
296 HMC AGL GLC 0.421053 0.717391
297 GCS GCS GCS GCS GCS 0.419355 0.804878
298 GCS GCS GCS GCS GCS GCS 0.419355 0.804878
299 GCS GCS GCS 0.419355 0.804878
300 GAL NAG GAL 0.418919 0.702128
301 GAL NGT 0.41791 0.66
302 P3M 0.41791 0.767442
303 NGT GAL 0.41791 0.66
304 ACR GLC GLC GLC GLC 0.417722 0.733333
305 ACR GLC 0.417722 0.733333
306 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
307 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
308 TUR 0.416667 0.842105
309 BTU 0.416667 0.842105
310 GLA MAN ABE 0.414286 0.916667
311 NAG NDG BMA 0.413333 0.634615
312 NAG NAG BMA 0.413333 0.634615
313 AHR AHR AHR 0.410714 0.857143
314 FUB AHR AHR 0.410714 0.857143
315 GLF B8D 0.409836 0.775
316 VAM 0.409836 0.868421
317 ACI G6D GLC ACI G6D BGC 0.409639 0.75
318 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.75
319 AC1 GLC AC1 BGC 0.409639 0.75
320 DAF GLC DAF GLC GLC 0.409639 0.75
321 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.75
322 ACI GLD GLC ACI G6D BGC 0.409639 0.75
323 MAN MMA MAN 0.409091 0.942857
324 AHR AHR 0.407407 0.857143
325 FUB AHR 0.407407 0.857143
326 NAG BMA MAN MAN MAN MAN 0.407407 0.733333
327 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.680851
328 4U0 0.406593 0.66
329 GLA MAN RAM ABE 0.405063 0.891892
330 BGC BGC SSG PIH 0.405063 0.767442
331 M1P 0.403846 0.697674
332 GL1 0.403846 0.697674
333 XGP 0.403846 0.697674
334 G1P 0.403846 0.697674
335 MAN IFM 0.403226 0.761905
336 GLC IFM 0.403226 0.761905
337 XZZ BGC BGC 0.402439 0.702128
338 ACG 0.402299 0.695652
339 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4WVW; Ligand: SLT; Similar sites found: 325
This union binding pocket(no: 1) in the query (biounit: 4wvw.bio1) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5DEY 59T 0.0005126 0.52636 None
2 2YG2 S1P 0.0002269 0.50843 None
3 2YG2 FLC 0.0002841 0.50843 None
4 1TT8 PHB 0.0006804 0.49187 None
5 1QY1 PRZ 0.0006256 0.48664 None
6 5HA0 LTD 0.0008755 0.47463 None
7 5DKK FMN 0.001115 0.46677 None
8 5VC5 96M 0.002096 0.46647 None
9 5DJT FMN 0.001967 0.45028 None
10 3IS2 FAD 0.005629 0.44138 None
11 4HIA FMN 0.005802 0.44073 None
12 4B1M FRU FRU 0.002474 0.44069 None
13 4B1L FRU 0.002459 0.43764 None
14 5IXH OTP 0.01365 0.4307 None
15 1SDW IYT 0.005631 0.4283 None
16 5NCF 8T5 0.004974 0.42811 None
17 3FW4 CAQ 0.00825 0.42674 None
18 3KFF ZBT 0.0006728 0.41269 None
19 3KFF XBT 0.0006728 0.41269 None
20 1I06 TZL 0.0122 0.411 None
21 4TW7 37K 0.02233 0.40809 None
22 5EPQ OLA 0.00492 0.433 1.38889
23 2VEG PMM 0.008911 0.41306 1.38889
24 4CME NAP 0.03253 0.40649 1.38889
25 2AG4 OLA 0.001819 0.49621 2.08333
26 2AG4 LP3 0.001982 0.49621 2.08333
27 5BYZ 4WE 0.0009039 0.47742 2.08333
28 5DQ8 FLF 0.001547 0.46772 2.08333
29 4IKR PVP 0.004606 0.45997 2.08333
30 3RGA LSB 0.001792 0.45236 2.08333
31 2AGC DAO 0.001351 0.45214 2.08333
32 5I0U DCY 0.002667 0.43695 2.08333
33 4AZW ATP 0.007744 0.42554 2.08333
34 3JU6 ANP 0.003916 0.42375 2.08333
35 2OVW CBI 0.008145 0.41637 2.08333
36 1DMY AZM 0.007213 0.41363 2.08333
37 1GCK ASP PLP 0.01308 0.40699 2.08333
38 2GGX NPJ 0.01717 0.4006 2.08333
39 4WN5 MVC 0.01303 0.40735 2.6087
40 1ZB6 GST 0.00008059 0.54569 2.77778
41 1ZB6 DIN 0.00007532 0.54569 2.77778
42 1NYW DAU 0.0004849 0.49853 2.77778
43 1F52 ADP 0.0004726 0.4848 2.77778
44 4HN1 TYD 0.0007095 0.47927 2.77778
45 3MF2 AMP 0.00102 0.47913 2.77778
46 1Y7P RIP 0.0003113 0.46729 2.77778
47 5MBC FMN 0.0023 0.45601 2.77778
48 4QJP V1F 0.002612 0.45072 2.77778
49 1URX AAL GAL AAL GLA 0.002059 0.44628 2.77778
50 4N1T 2GD 0.01978 0.42637 2.77778
51 2HZQ STR 0.002916 0.42554 2.77778
52 5X1M THG 0.01729 0.41804 2.77778
53 5X1M DHB 0.01817 0.41488 2.77778
54 3W7T BMA 0.01747 0.41366 2.77778
55 3N0Y APC 0.0142 0.40596 2.77778
56 2Y88 2ER 0.02141 0.40455 2.77778
57 4F7E 0SH 0.0394 0.40384 2.77778
58 4IAW LIZ 0.0004148 0.40235 2.77778
59 1Y2F WAI 0.002628 0.42331 2.8777
60 4XV1 904 0.0004313 0.52185 3.47222
61 4ZU4 4TG 0.0001478 0.51952 3.47222
62 4WHZ 3NL 0.001548 0.49541 3.47222
63 3G08 FEE 0.004675 0.48529 3.47222
64 4QMN DB8 0.002165 0.48135 3.47222
65 4RPL 3UC 0.01103 0.47169 3.47222
66 5ML3 DL3 0.005322 0.45239 3.47222
67 4XBT FLC 0.00379 0.45132 3.47222
68 4XBT 3ZQ 0.004055 0.44936 3.47222
69 3E7O 35F 0.006374 0.44098 3.47222
70 4RLT FSE 0.00315 0.43839 3.47222
71 1UU6 BGC BGC BGC BGC 0.008772 0.43485 3.47222
72 4GJ3 0XP 0.006495 0.43448 3.47222
73 4UWJ MYA 0.0117 0.4342 3.47222
74 4UWJ 7L5 0.0117 0.4342 3.47222
75 4OCV ANP 0.005762 0.43415 3.47222
76 5FP3 3JI 0.009247 0.42232 3.47222
77 2BNJ XYP XYP AHR FER 0.0111 0.42155 3.47222
78 2ABS ACP 0.02927 0.40903 3.47222
79 3LXK MI1 0.0178 0.40289 3.47222
80 1X0P FAD 0.00357 0.44168 3.4965
81 4R38 RBF 0.01085 0.41581 3.57143
82 3AGC RCC 0.003316 0.45878 3.98551
83 3DJV C3P 0.0483 0.41305 4.03226
84 4ZSI 4R1 0.00005317 0.54035 4.16667
85 4ZSI GLP 0.0004438 0.47937 4.16667
86 1QZY TDE 0.001358 0.47747 4.16667
87 2OAZ I96 0.001829 0.47171 4.16667
88 2I74 MAN MAN MAN MAN 0.0006673 0.4666 4.16667
89 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 0.01292 0.45668 4.16667
90 5JSP DQY 0.001066 0.45458 4.16667
91 5U98 1KX 0.006816 0.45392 4.16667
92 4J7Q B7N 0.004578 0.45353 4.16667
93 3ILR SGN IXD 0.01508 0.44269 4.16667
94 5FAL COA 0.01729 0.44112 4.16667
95 5FAL SKT 0.01729 0.44112 4.16667
96 3T1A 5MA 0.006714 0.43986 4.16667
97 5H2D ERG 0.006044 0.43611 4.16667
98 4ZSD 7I6 0.005469 0.43119 4.16667
99 3DNT ATP 0.01366 0.42185 4.16667
100 2BMB PMM 0.009435 0.4189 4.16667
101 1DY4 SNP 0.04718 0.41793 4.16667
102 4XDA ADP 0.01546 0.41698 4.16667
103 3ACL 3F1 0.009369 0.41357 4.16667
104 1SNN 5RP 0.009388 0.40935 4.16667
105 2QK4 ATP 0.01545 0.40541 4.16667
106 3II1 BGC 0.009766 0.40289 4.16667
107 2V58 LZJ 0.03955 0.40066 4.16667
108 2BWA GLC BGC 0.01135 0.40027 4.16667
109 5KEW 6SB 0.001447 0.44414 4.25532
110 5LJB RTL 0.02255 0.4027 4.44444
111 2P7Q GG6 0.003707 0.42023 4.51128
112 5W10 CMP 0.000609 0.48443 4.86111
113 1IIU RTL 0.003147 0.45997 4.86111
114 4GCZ FMN 0.001295 0.45966 4.86111
115 2JIG PD2 0.00202 0.44053 4.86111
116 3L9R L9Q 0.00902 0.43815 4.86111
117 4WW7 AMP 0.005265 0.43635 4.86111
118 2HK5 1BM 0.006285 0.43635 4.86111
119 4WUJ FMN 0.006159 0.43191 4.86111
120 3AVS OGA 0.006696 0.43046 4.86111
121 3W8X FTK 0.002689 0.43031 4.86111
122 5DYO FLU 0.002539 0.4264 4.86111
123 4QM9 CYS 0.003011 0.42612 4.86111
124 5IH9 6BF 0.01206 0.42423 4.86111
125 3A7R LAQ 0.01527 0.42184 4.86111
126 3AJH BL3 0.006373 0.41263 4.86111
127 3V8S 0HD 0.008924 0.40952 4.86111
128 3H22 B53 0.04004 0.4057 4.86111
129 5F3I 5UJ 0.04004 0.40467 4.86111
130 4HWT 1B2 0.009639 0.40185 4.86111
131 5KR7 6X9 0.0153 0.40037 4.86111
132 3F7Z 34O 0.03746 0.40009 4.86111
133 1P0Z FLC 0.001371 0.44856 5.34351
134 2Z6D FMN 0.009319 0.40586 5.38462
135 2WKQ FMN 0.001284 0.46274 5.55556
136 3AKK ADP 0.002096 0.46058 5.55556
137 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 0.006022 0.4545 5.55556
138 1Z03 OCH 0.001636 0.45449 5.55556
139 4BR5 ANP 0.004405 0.45445 5.55556
140 4L4J NAG NAG BMA MAN NAG 0.0005362 0.44359 5.55556
141 3KDJ A8S 0.004926 0.43756 5.55556
142 3JRS A8S 0.005532 0.43661 5.55556
143 3UN3 G16 0.005266 0.43586 5.55556
144 1I82 BGC BGC 0.002842 0.4349 5.55556
145 4DW4 U5P 0.006036 0.43264 5.55556
146 2YNE NHW 0.02591 0.43071 5.55556
147 2YNE YNE 0.02591 0.43071 5.55556
148 4JJJ CE6 0.01138 0.42949 5.55556
149 2C49 ADN 0.01036 0.42807 5.55556
150 3OJI PYV 0.00777 0.42368 5.55556
151 3RE4 TO1 0.009336 0.4213 5.55556
152 3TYZ XHP 0.0182 0.42105 5.55556
153 3TYZ PAB 0.02037 0.42105 5.55556
154 2AXR ABL 0.003871 0.42071 5.55556
155 2ARC ARA 0.006362 0.41413 5.55556
156 2TPS TPS 0.01989 0.41291 5.55556
157 4AZI OAN 0.01113 0.40904 5.55556
158 3B1Q NOS 0.03755 0.40737 5.55556
159 2ZYI STE 0.02123 0.40628 5.55556
160 2VFT SOR 0.0003289 0.40544 5.55556
161 4NPL AKG 0.01658 0.40238 5.55556
162 5J75 6GQ 0.01115 0.40018 5.55556
163 4IPH 1FJ 0.004843 0.43745 5.69106
164 1U0A BGC BGC BGC BGC 0.00006672 0.51709 6.25
165 4D06 NAR 0.001335 0.47107 6.25
166 2XXP DSL 0.007175 0.46187 6.25
167 4DE9 VTP 0.003146 0.46147 6.25
168 4ANW O92 0.008078 0.4424 6.25
169 4P7X YCP 0.003849 0.43537 6.25
170 4P7X AKG 0.003849 0.43537 6.25
171 5MJA 7O3 0.004585 0.43387 6.25
172 5DXT 5H5 0.006466 0.43209 6.25
173 4NG2 OHN 0.00913 0.42415 6.25
174 3IX8 TX3 0.01036 0.42281 6.25
175 3EEB IHP 0.008076 0.41855 6.25
176 1UMZ BGC BGC XYS BGC XYS GAL 0.004068 0.41812 6.25
177 2WFG ZZB 0.01251 0.41417 6.25
178 5ISY NAD 0.009983 0.40645 6.25
179 3GD9 GLC BGC BGC BGC 0.009136 0.40608 6.25
180 4JE5 PMP 0.01239 0.40521 6.25
181 4JE5 PLP 0.01534 0.40086 6.25
182 4YZC STU 0.000244 0.52263 6.94444
183 4RFR RHN 0.0001713 0.51417 6.94444
184 3VQ2 LP4 LP5 MYR DAO 0.001626 0.49512 6.94444
185 2E9L OLA 0.001582 0.48484 6.94444
186 2E9L BGC 0.001582 0.48484 6.94444
187 2E9L PLM 0.001513 0.48484 6.94444
188 4LOO SB4 0.001105 0.47492 6.94444
189 3FON VAL ASN ASP ILE PHE GLU ALA ILE 0.001923 0.47395 6.94444
190 3W68 VIV 0.001052 0.47168 6.94444
191 4BVA T3 0.00367 0.46237 6.94444
192 2YKL NLD 0.001115 0.45587 6.94444
193 2HGZ PBF 0.01872 0.44206 6.94444
194 3PQB VGP 0.003131 0.43758 6.94444
195 1IF7 SBR 0.02446 0.43703 6.94444
196 3QP8 HL0 0.004599 0.43089 6.94444
197 5BU3 4W9 0.005848 0.43088 6.94444
198 5X7Q GLC GLC GLC BGC 0.01544 0.42468 6.94444
199 1G9J BGC SGC BGC SGC BGC SGC BGC SGC 0.03701 0.42463 6.94444
200 1H8S AIC 0.005646 0.42264 6.94444
201 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 0.02892 0.41408 6.94444
202 4U0I 0LI 0.02292 0.40867 6.94444
203 5W0N UPU 0.01327 0.4014 6.94444
204 4PFC 2QX 0.04142 0.40072 6.94444
205 3TCT 3MI 0.009195 0.48483 7.08661
206 4QXB OGA 0.002659 0.42545 7.35294
207 5FU3 BGC BGC BGC 0.00004311 0.46936 7.54717
208 4P8K 38C 0.003237 0.48444 7.63889
209 4P8K FAD 0.003237 0.48444 7.63889
210 2Y6O 1N1 0.003027 0.45713 7.63889
211 1LEK GLU GLN TYR LYS PHE TYR SER VAL 0.01099 0.45534 7.63889
212 1GP6 DH2 0.003361 0.45277 7.63889
213 1GP6 SIN 0.003361 0.45277 7.63889
214 1ODM ASV 0.006356 0.44394 7.63889
215 3Q8G PEE 0.01229 0.44022 7.63889
216 2XVD AS6 0.00869 0.43405 7.63889
217 3SXS PP2 0.006498 0.43137 7.63889
218 1CZA G6P 0.0102 0.41656 7.63889
219 4RYV ZEA 0.01433 0.41542 7.63889
220 1PN0 IPH 0.04868 0.41396 7.63889
221 1GP6 QUE 0.02364 0.40197 7.63889
222 4K3H 1OM 0.02181 0.40032 7.63889
223 2E27 AB0 0.01241 0.40804 7.93651
224 3HMO STU 0.01474 0.40609 8.18713
225 1KQW RTL 0.01423 0.40165 8.20895
226 4KYS VIB 0.0002034 0.49611 8.33333
227 3B6R ADP 0.001589 0.45854 8.33333
228 4EIP FAD 0.009078 0.45838 8.33333
229 4EIP K2C 0.009078 0.45838 8.33333
230 5MZI FAD 0.008563 0.45635 8.33333
231 5MZI FYK 0.008775 0.45635 8.33333
232 1GQG DCD 0.001824 0.45526 8.33333
233 1U6R ADP 0.002549 0.44746 8.33333
234 4WOE ADP 0.0009931 0.445 8.33333
235 5HCY 60D 0.006868 0.43932 8.33333
236 4V24 GYR 0.01583 0.42161 8.33333
237 4L9I 8PR 0.009901 0.4179 8.33333
238 5D9G GLU ASN LEU TYR PHE GLN 0.00854 0.4109 8.33333
239 3F5K CE5 0.01151 0.4097 8.33333
240 4X6F 3XU 0.01869 0.43606 8.57143
241 2HRL SIA GAL SIA BGC NGA CEQ 0.000977 0.44966 8.66142
242 5SVV FMN 0.001226 0.46621 8.75912
243 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 0.001826 0.47614 9
244 4XLI 1N1 0.001326 0.47674 9.02778
245 5LRT ADP 0.005132 0.4371 9.02778
246 5L2J 6UL 0.03267 0.43317 9.02778
247 5L2J 70E 0.03406 0.43317 9.02778
248 3QUZ QUV 0.02585 0.43158 9.02778
249 5HV0 AKG 0.005379 0.42945 9.02778
250 1S4M LUM 0.01498 0.42202 9.02778
251 3AMN CBK 0.02018 0.41827 9.02778
252 3AMN CBI 0.02018 0.41827 9.02778
253 2H8H H8H 0.02113 0.41156 9.02778
254 4MA6 28E 0.007477 0.40895 9.02778
255 2IPI AKY 0.009585 0.40811 9.02778
256 5F7V GLC GLC GLC GLC 0.02238 0.40418 9.02778
257 4H2V AMP 0.003581 0.45328 9.09091
258 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 0.005102 0.46617 9.72222
259 2GJ5 VD3 0.02293 0.41567 9.72222
260 1M0W ANP 0.01565 0.4069 9.72222
261 4XOE KGM 0.009257 0.40056 9.72222
262 4XIZ LPP 0.03272 0.40026 9.72222
263 4D2S DYK 0.006293 0.42518 9.85915
264 3M3E GAL A2G NPO 0.0000003351 0.63174 10.4167
265 3SCM LGN 0.004254 0.49005 10.4167
266 5VCV 1N1 0.001818 0.47501 10.4167
267 5VSM 5AD 0.008624 0.4237 10.4167
268 3MTX PGT 0.008989 0.41569 10.4167
269 3MVH WFE 0.024 0.40224 10.4167
270 1KGI T4A 0.01088 0.41126 11.0236
271 1ZM1 BGC BGC BGC 0.00007809 0.51697 11.1111
272 3FW9 SLX 0.0002403 0.50932 11.1111
273 1MJJ HAL 0.003601 0.45037 11.1111
274 5LUN OGA 0.006604 0.41739 11.1111
275 3ZGJ RMN 0.009843 0.41209 11.1111
276 2RG0 CTT 0.01842 0.40719 11.1111
277 4K55 H6P 0.0000676 0.49547 11.2903
278 2A1L PCW 0.0001885 0.55614 11.8056
279 2XMY CDK 0.000222 0.55436 11.8056
280 4MNS 2AX 0.002158 0.47316 11.8056
281 5FXD H7Y 0.001351 0.46964 11.8056
282 4Q0L V14 0.002663 0.45659 11.8056
283 3LVW GSH 0.007009 0.44299 11.8056
284 1I7E IBS 0.002226 0.43013 11.8056
285 3U6W KIV 0.005479 0.40799 11.8056
286 4QA8 PJZ 0.02 0.40368 11.8056
287 2PVN P63 0.02938 0.40238 11.8056
288 3QRC SCR 0.00002127 0.47069 12.5
289 1J3R 6PG 0.0007051 0.46862 12.5
290 4D1J DGJ 0.002137 0.43142 12.5
291 2CER PGI 0.0179 0.42313 12.5
292 4H2W 5GP 0.0001142 0.53025 13.1944
293 4H2W AMP 0.0001361 0.52159 13.1944
294 4W8B GLC BGC BGC XYS BGC XYS XYS GAL 0.001239 0.47454 13.1944
295 5FBN 5WF 0.003408 0.46579 13.1944
296 3T4L ZEA 0.01188 0.40573 13.1944
297 4JH6 FCN 0.0001817 0.50245 13.7681
298 4FHD EEM 0.004328 0.45667 13.8889
299 4FHD 0TT 0.004328 0.45667 13.8889
300 4OMJ 2TX 0.002313 0.45295 13.8889
301 1OLM VTQ 0.001819 0.44966 13.8889
302 4CSS CWX 0.008658 0.41581 14.5833
303 4ZLU 4PW 0.04349 0.40865 14.5833
304 4ZLU ADP 0.04349 0.40865 14.5833
305 1XI9 PLP 0.01271 0.40062 14.5833
306 5BVE 4VG 0.0002025 0.54606 15.2778
307 5HES 032 0.001042 0.48643 15.2778
308 2CWH NDP 0.02603 0.40727 15.2778
309 1Q6O LG6 0.0434 0.41459 15.9722
310 5A65 TPP 0.0002219 0.51883 16.6667
311 5N87 N66 0.001024 0.48474 16.6667
312 2RDQ AKG 0.004619 0.44026 16.6667
313 5VNF VAL THR SER VAL VAL 0.001456 0.43706 16.6667
314 5H2U 1N1 0.007575 0.42798 16.6667
315 2Z77 HE7 0.002367 0.45456 17.2662
316 4NFN 2KC 0.003065 0.4515 18.0556
317 3ETH ATP 0.01096 0.41801 18.75
318 4TWL ASC 0.008697 0.40829 19.4444
319 3NW7 LGV 0.03506 0.40639 20.8333
320 1K3A ACP 0.02412 0.40378 20.8333
321 2FNU PMP UD1 0.04761 0.40136 22.2222
322 4MLO PAM 0.002164 0.4578 25
323 4YZT BGC BGC BGC BGC 0.008666 0.43033 27.7778
324 3VV1 GAL FUC 0.000000001292 0.76742 34.7222
325 1QKQ MAN 0.00000001368 0.72386 37.3239
Feedback