Receptor
PDB id Resolution Class Description Source Keywords
4UX9 2.34 Å EC: 2.7.11.24 CRYSTAL STRUCTURE OF JNK1 BOUND TO A MKK7 DOCKING MOTIF HOMO SAPIENS TRANSFERASE JNK1 INTRINSICALLY DISORDERED DOMAINS MKK7
Ref.: STRUCTURE AND DYNAMICS OF THE MKK7-JNK SIGNALING CO PROC.NATL.ACAD.SCI.USA V. 112 3409 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 B:1364;
A:1364;
D:1367;
A:1365;
C:1366;
A:1366;
C:1365;
A:1367;
H:1049;
B:1363;
C:1367;
C:1364;
B:1365;
B:1366;
D:1366;
D:1365;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
ANP B:1000;
A:1000;
D:1000;
C:1000;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4UX9 2.34 Å EC: 2.7.11.24 CRYSTAL STRUCTURE OF JNK1 BOUND TO A MKK7 DOCKING MOTIF HOMO SAPIENS TRANSFERASE JNK1 INTRINSICALLY DISORDERED DOMAINS MKK7
Ref.: STRUCTURE AND DYNAMICS OF THE MKK7-JNK SIGNALING CO PROC.NATL.ACAD.SCI.USA V. 112 3409 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 4UX9 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 4UX9 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 4UX9 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4UX9; Ligand: ANP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4ux9.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4UX9; Ligand: ANP; Similar sites found: 337
This union binding pocket(no: 2) in the query (biounit: 4ux9.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2VPQ ANP 0.0000331 0.50176 1.92308
2 3PUR 2HG 0.02093 0.40708 1.92308
3 5TDF ADP 0.001842 0.4233 2.16049
4 4DFU QUE 0.01209 0.41849 2.17391
5 3WVR AMP 0.0001619 0.4478 2.1978
6 4U98 ACP 0.0003894 0.43963 2.1978
7 1EHI ADP 0.002517 0.41418 2.1978
8 5IGI ZIT 0.01502 0.40448 2.32558
9 5IGI GMP 0.01424 0.40448 2.32558
10 3ZJX BOG 0.008133 0.42683 2.42215
11 5I35 ANP 0.0000005661 0.55139 2.47253
12 4OYA 1VE 0.03272 0.4065 2.47253
13 5C4L 4XR 0.00001073 0.5371 2.49221
14 5C4L SIS 0.000152 0.48615 2.49221
15 4OCV ANP 0.00002897 0.49474 2.74725
16 5C1P DAL DAL 0.001813 0.43084 2.94118
17 5C1P ADP 0.0008242 0.41888 2.94118
18 3V4S ATP 0.001227 0.43274 3.02198
19 3VOT ADP 0.0002289 0.427 3.02198
20 4PU5 ANP 0.000924 0.42555 3.02198
21 3V4S ADP 0.005488 0.42211 3.02198
22 5NCY 8TK 0.0105 0.40337 3.02198
23 1I7L ATP 0.0001012 0.48307 3.23625
24 2IO8 ADP 0.0007485 0.44568 3.2967
25 1F0X FAD 0.01688 0.40416 3.2967
26 5FS0 5JC 0.01707 0.40644 3.31754
27 4R78 AMP 0.0000156 0.46718 3.55987
28 2VQD AP2 0.0001044 0.47603 3.57143
29 2PUL ACP 0.003211 0.43606 3.57143
30 3ILR IXD 0.02564 0.40188 3.57143
31 3ILR SGN 0.02564 0.40188 3.57143
32 3ILR SGN IXD 0.0287 0.40188 3.57143
33 1OBD ATP 0.000756 0.4133 3.59477
34 5GZ9 ANP 0.000000000229 0.72252 3.60656
35 4MV1 ADP 0.005924 0.41699 3.63248
36 3ETH ATP 0.0002935 0.45917 3.66197
37 4JB1 NAP 0.02211 0.40649 3.82353
38 4JB1 FAD 0.02295 0.40649 3.82353
39 4C5N PXL 0.0056 0.42054 3.98551
40 4C5N ACP 0.005261 0.42054 3.98551
41 5C03 AGS 0.000002758 0.53031 4.09357
42 1M0W ANP 0.00289 0.40131 4.12088
43 2Q7D ANP 0.00309 0.42242 4.33526
44 3TII ANP 0.0004433 0.41695 4.3956
45 3K5I ADP 0.003024 0.41418 4.3956
46 3K5I AIR 0.01276 0.40211 4.3956
47 4WOV 3SM 0.00002877 0.46739 4.4164
48 4ZGP ADP 0.001304 0.41734 4.43686
49 4OUC 5ID 0.00000001352 0.59687 4.48179
50 2GQR ADP 0.002064 0.40756 4.64135
51 5W2I ADP 0.00005975 0.49291 4.66926
52 5W2I I3P 0.00005975 0.49291 4.66926
53 5DMZ ADP 0.000000000221 0.69272 4.67033
54 2PYW ADP 0.000006636 0.52662 4.67033
55 5VZ0 ADP 0.00006905 0.46677 4.67033
56 2IF8 ADP 0.0001036 0.4283 4.6832
57 3KAL ADP 0.005259 0.42055 4.94506
58 3VPC ADP 0.0001715 0.4691 4.96454
59 3I0O ADP 0.00009 0.44633 5.01475
60 3RE4 TO1 0.00002502 0.46264 5.03876
61 1PK8 ATP 0.00004934 0.49855 5.21978
62 2AQX ATP 0.0005242 0.44845 5.53633
63 5IH1 GDP 0.009103 0.42465 5.96026
64 5IH1 6BQ 0.0112 0.42042 5.96026
65 3HAV ATP 0.003355 0.42086 6.02007
66 5MW8 ATP 0.0000004499 0.58163 6.04396
67 3AKK ADP 0.0008933 0.43333 6.15385
68 1IOW PHY 0.0006559 0.4623 6.20915
69 1IOW ADP 0.0006559 0.4623 6.20915
70 4O1P ANP 0.000000003869 0.64418 6.31868
71 4CYI ATP 0.000005044 0.53166 6.31868
72 5CKW ANP 0.00002426 0.46921 6.31868
73 4ANW O92 0.001471 0.44391 6.31868
74 2BKK ADP 0.00005768 0.45866 6.43939
75 3TM0 ANP 0.0002081 0.40742 6.46388
76 3TM0 B31 0.0002249 0.40211 6.46388
77 5IQD RIO 0.0002995 0.48161 6.55738
78 5IQD GNP 0.0002801 0.48161 6.55738
79 5USZ SKE 0.0000001086 0.61849 6.57439
80 5TT6 ATP 0.006566 0.4017 6.59341
81 3KA2 2NC 0.007066 0.43065 6.89655
82 3UDZ ADP 0.000001996 0.54109 7.14286
83 4GYI ADP 0.000003272 0.57444 7.41758
84 2GQS ADP 0.001414 0.4147 7.59494
85 1T36 ADP 0.004193 0.41815 7.69231
86 1IA9 ANP 0.0000182 0.5137 7.85714
87 3ORQ ADP 0.0006759 0.44171 7.96703
88 3DNT ATP 0.001008 0.44011 7.96703
89 4IX4 ADP 0.00002002 0.50634 8
90 3TDV GDP 0.0000009447 0.54834 8.16993
91 4OCJ NDG 0.00002669 0.52915 8.24176
92 4XYM A12 0.0006098 0.43935 8.26087
93 3W0O HY0 0.0004786 0.46257 8.59599
94 3W0O ADP 0.0004786 0.46257 8.59599
95 4OAV ACP 0.00000001662 0.60622 8.79121
96 5M06 ADP 0.000001171 0.52676 9.05797
97 4I94 ANP 0.00000001081 0.60962 9.33333
98 4G17 0VN 0.000003609 0.5057 9.39394
99 2YW2 ATP 0.004031 0.40889 9.61539
100 4AZW ATP 0.0006179 0.44336 10.1648
101 4WW7 AMP 0.000008584 0.52442 10.6952
102 3VPB ADP 0.00005837 0.49539 10.7143
103 2V58 LZJ 0.0006426 0.47352 10.989
104 1IDA 0PO 0.01541 0.40293 11.1111
105 2P3C 3TL 0.01826 0.40162 11.1111
106 1ZP9 ATP 0.000003607 0.50862 11.6279
107 1ZTH ADP 0.000001228 0.50845 11.6279
108 4Q5H ANP 0.000002966 0.52887 12.069
109 3VHE 42Q 0.0000001324 0.61938 12.2563
110 1TQP ATP 0.00002226 0.51136 12.4113
111 1W2D 4IP 0.001455 0.43979 12.4528
112 1W2D ADP 0.000382 0.42101 12.4528
113 4O4F ATP 0.000662 0.44978 12.9032
114 4O4F IHP 0.0009008 0.4457 12.9032
115 3UIM ANP 0.0000000175 0.61669 13.1902
116 3PP0 03Q 0.0000000608 0.55334 13.3136
117 5G5G FAD 0.01314 0.41202 13.5371
118 4XH0 ADP 0.0000002224 0.66734 13.7363
119 3Q60 ATP 0.0000009052 0.54056 14.2857
120 2X2M X2M 0.00000002826 0.63002 14.3312
121 4Y85 499 0.0000004173 0.55122 14.759
122 5K2M ADP 0.0001862 0.47168 15.0943
123 3KMW ATP 0.000119 0.45597 15.4982
124 3PVW QRX 0.000000008258 0.58944 15.6593
125 3BU1 HSM 0.01462 0.40343 16.2162
126 4YHQ G10 0.009837 0.40954 17.1717
127 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.000000006042 0.72114 17.2515
128 2JDR L20 0.000000006042 0.72114 17.2515
129 4ZS4 ATP 0.000006486 0.52114 17.5896
130 4LRJ ANP 0.00000007529 0.58261 17.7515
131 1VJY 460 0.000000001347 0.71226 17.8218
132 3GNI ATP 0.00000000329 0.66635 18.6813
133 4FL3 ANP 0.000000004475 0.66407 19.2308
134 5UKL SIX 0.000000008788 0.66617 19.3548
135 2PZI AXX 0.000006017 0.56193 19.5055
136 3PDT ADP 0.000007683 0.50134 19.6364
137 4L9I 8PR 0.0000001561 0.57154 20.2381
138 5T8O 76Z 0.00000004141 0.61984 20.6304
139 5VC5 96M 0.0000004741 0.59054 20.7612
140 3OV6 MK0 0.0118 0.4024 20.9068
141 4DC2 ADE 0.000000009933 0.51471 21.4286
142 4EUU BX7 0.00000005042 0.63051 22.2571
143 4U44 3D9 0.0000001381 0.57848 23.7952
144 4OTH DRN 0.000000009167 0.65082 24.0469
145 3C1X CKK 0.00008552 0.48195 24.1758
146 4BTK DTQ 0.0000004863 0.55993 24.6291
147 4P5Z Q7M 0.000003436 0.56946 24.6537
148 4ASE AV9 0.000001634 0.56706 25.4958
149 2CSN CKI 0.00005161 0.53599 25.5892
150 2OO8 RAJ 0.0004952 0.44951 25.8675
151 3VRY B43 0.000002499 0.50595 26.0989
152 4OH4 ANP 0.00000001326 0.62187 26.1261
153 4NFN 2KC 0.00001224 0.49706 26.2136
154 5LPZ ADP 0.000000005482 0.63583 26.506
155 3KRL KRL 0.000004321 0.5371 26.5672
156 4Y0X ADP 0.0000001291 0.56471 26.6667
157 4F9C 0SX 0.000000000253 0.67805 26.8698
158 4E93 GUI 0.00000008625 0.63199 26.9231
159 3MVH WFE 0.000000004393 0.68455 27.193
160 3V8S 0HD 0.000000005432 0.62408 27.1978
161 4WNK 453 0.0000000003708 0.73187 27.4725
162 5W4W 9WG 0.000002223 0.56736 27.4924
163 4KBA 1QM 0.00002665 0.51412 27.4924
164 5EOB 5QQ 0.0000007852 0.61865 27.8997
165 5LI9 ACP 0.0000000009952 0.69776 28
166 4K33 ACP 0.000000001156 0.67487 28
167 2R5T ANP 0.0001016 0.51391 28.022
168 5HCY 60D 0.00000007294 0.65393 28.0967
169 2PVF ACP 0.000000001772 0.64471 28.1437
170 3H9R TAK 0.0000002277 0.5128 28.1818
171 1U5R ATP 0.0000351 0.52519 28.4483
172 4AG8 AXI 0.0000003513 0.46758 28.481
173 3GQI ACP 0.000000001892 0.65371 28.5276
174 5LI1 ANP 0.00000000003573 0.7533 28.8136
175 4WB7 ATP 0.0000000002177 0.7549 28.8462
176 5TO8 7FM 0.00000831 0.55361 29.078
177 5LPB ADP 0.000000138 0.53755 29.3919
178 2H8H H8H 0.00000005709 0.5937 29.3956
179 1Y57 MPZ 0.0000008019 0.57089 29.3956
180 3TKI S25 0.0000001389 0.65277 29.4118
181 4X7Q 3YR 0.000000006463 0.67182 29.4872
182 2HY0 306 0.0000004368 0.52882 29.5031
183 5HVJ ANP 0.000000232 0.48397 29.5238
184 5JFS 6K0 0.0000009436 0.59816 29.5455
185 2Y6O 1N1 0.000003355 0.54178 29.5533
186 3RI1 3RH 0.00000007373 0.62333 29.7125
187 3FHI ANP 0.000000000008737 0.79397 29.7143
188 2QCS ANP 0.00000000001117 0.78934 29.7143
189 1RE8 BD2 0.0000000007717 0.74854 29.7143
190 3IDB ANP 0.0000000004244 0.71106 29.7143
191 5UR1 YY9 0.000003259 0.57659 29.9035
192 4QMN DB8 0.000001485 0.58255 30
193 3FHR P4O 0.0000001662 0.60178 30.0595
194 3HMO STU 0.00000002404 0.59858 30.117
195 3PLS ANP 0.000000007876 0.62244 30.2013
196 4YMJ 4EJ 0.0000005565 0.48584 30.2632
197 4WB6 ATP 0.00000000001854 0.77977 30.2857
198 5AX9 4KT 0.00000002365 0.60881 30.5195
199 4BHN BH9 0.0000000102 0.64558 30.5389
200 3GGF GVD 0.000000007819 0.60663 30.5648
201 5DRB 5FJ 0.000002624 0.58513 30.5842
202 3TXO 07U 0.00000003692 0.5843 30.5949
203 5UIU 8CG 0.000000001594 0.70396 30.6502
204 5DH3 5BS 0.00000011 0.6019 30.7937
205 2GU8 796 0.0000000009265 0.75818 30.8605
206 5JKG 6LF 0.000001895 0.58116 30.8682
207 4Y8D 49J 0.00000006336 0.59238 30.8824
208 1BYG STU 0.000000001714 0.63181 30.9353
209 4E1Z 0MX 0.00000004995 0.62247 31.2715
210 4YZN 4K5 0.0000000005154 0.70745 31.3589
211 3NW7 LGV 0.000001679 0.5941 31.5961
212 4AT3 LTI 0.000002897 0.56032 31.7726
213 4M69 ANP 0.000000006785 0.65306 31.8021
214 3SLS ANP 0.0000000006448 0.69986 31.9079
215 5NKB 8ZT 0.000000933 0.43304 32.3529
216 1K3A ACP 0.0000002773 0.54335 32.4415
217 5N87 N66 0.000000008416 0.68355 32.5879
218 4BKJ STI 0.0003079 0.46416 32.6984
219 3LXK MI1 0.00000001679 0.65389 32.7217
220 2XVD AS6 0.0000003096 0.60091 32.7815
221 5MJA 7O3 0.0000002654 0.54649 32.7869
222 5KO1 6UY 0.00000005949 0.5838 32.8622
223 4U0I 0LI 0.00001008 0.53832 33.0159
224 3ORK AGS 0.00000001545 0.65009 33.119
225 5VCV 1N1 0.00000008081 0.61633 33.119
226 3SXS PP2 0.0000005203 0.57337 33.209
227 1U59 STU 0.00000002623 0.60994 33.4495
228 4USF 6UI 0.00002162 0.5119 33.5526
229 3AQV TAK 0.0001898 0.45358 33.6957
230 4JR7 GNP 0.0000000001735 0.69511 33.7912
231 2OFV 242 0.000002202 0.57486 34.296
232 1OPK P16 0.000004823 0.55248 34.3407
233 5JGA 6KC 0.00000006334 0.63795 34.6032
234 4WNP 3RJ 0.00000000427 0.605 34.8432
235 1JPA ANP 0.0000002756 0.40259 34.9359
236 4NW6 2NS 0.0000000006919 0.72512 34.9845
237 5FBN 5WF 0.0000004148 0.60558 35.0554
238 4A4X JUP 0.000002426 0.55739 35.1254
239 3KRR DQX 0.00000006669 0.67917 35.2542
240 2HK5 1BM 0.000000297 0.58367 35.5556
241 2YAB AMP 0.000000001939 0.66633 35.7341
242 5HX8 66P 0.00000002445 0.64417 35.7616
243 4G31 0WH 0.00002352 0.52542 35.786
244 4D2S DYK 0.00000003659 0.56429 35.9155
245 5CEO 50D 0.0000004789 0.55785 36
246 4YZC STU 0.00000000141 0.72064 36.2637
247 4N70 2HX 0.0000000273 0.68004 36.2805
248 2QLU ADE 0.00000007884 0.44665 36.3057
249 4CSV STI 0.00003324 0.50169 36.3636
250 2ZV2 609 0.000000008871 0.70697 36.5772
251 5TA6 79D 0.000007801 0.53742 36.8715
252 3DAK ANP 0.0000000904 0.56445 36.8966
253 3DLS ADP 0.000000008506 0.6046 37.0149
254 3C0G 3AM 0.0000002364 0.54432 37.0879
255 4EWH T77 0.00000005419 0.63167 37.4545
256 5UOX 8GY 0.00000001673 0.63971 37.6384
257 3G5D 1N1 0.0000008141 0.61913 37.7622
258 5DBX ANP 0.000000004989 0.60012 37.8049
259 3CY2 MB9 0.00000005009 0.62242 37.8981
260 2RIO ADP 0.00000000002389 0.7171 37.9121
261 3ALN ANP 0.000000001987 0.67561 37.9205
262 2Z7R STU 0.00000000009812 0.73464 38.0062
263 5HES 032 0.0000005658 0.57466 38.1107
264 4RFM 3P6 0.00001396 0.55402 38.3459
265 2WU6 DKI 0.000000008456 0.65547 39.011
266 2WQN ADP 0.00000001779 0.68149 39.3548
267 3FC2 IBI 0.000192 0.51569 39.403
268 2WEL K88 0.0000000806 0.50909 39.4495
269 3HZT J60 0.00000007394 0.5481 39.5604
270 2V7O DRN 0.00000002143 0.56006 39.5833
271 5H2U 1N1 0.00001102 0.50303 39.7004
272 4JDI ANP 0.000000007679 0.65079 39.8844
273 5DA3 58V 0.00000004864 0.55123 40
274 3M2W L8I 0.0000000008654 0.63207 40.1338
275 4CRL C1I 0.0000003318 0.60799 40.3846
276 3IGO ANP 0.000000004013 0.64776 40.6593
277 3E8N VRA 0.00005014 0.56099 41.0557
278 3E8N ATP 0.00005014 0.56099 41.0557
279 3SRV S19 0.0000000009125 0.65613 41.1552
280 5A6N U7E 0.00000001974 0.6252 41.3428
281 3SXF BK5 0.0000002103 0.61879 41.4835
282 5IH9 6BF 0.00000008314 0.63883 41.4925
283 1PHK ATP 0.00000000001556 0.75127 41.6107
284 4IDT T28 0.0000000008544 0.65406 41.6667
285 4FF8 14S 0.0007433 0.41042 41.6667
286 5FJN BE2 0.02093 0.40521 41.6667
287 5FJN FAD 0.01925 0.40521 41.6667
288 4F4P 0SB 0.000002566 0.59894 41.7582
289 2PVN P63 0.0000000003711 0.72907 41.7614
290 5LVP ATP 0.000000003578 0.61256 42.1222
291 4BFM ANP 0.000000000084 0.7337 42.515
292 5LXC 7AA 0.0000000004565 0.65356 42.8571
293 3QCQ 3Q0 0.00000007058 0.69633 42.9487
294 2VZ6 FEF 0.00000002942 0.67116 43.131
295 4YLL 4E3 0.000000004336 0.66788 43.2133
296 2A19 ANP 0.0000001094 0.65413 43.3099
297 5MY8 RXZ 0.0000004582 0.58643 43.4066
298 4FG8 ATP 0.0000000006045 0.69746 43.4921
299 4C2V YJA 0.0000001775 0.61376 43.5088
300 2VN9 GVD 0.0000000106 0.56608 43.5216
301 2F57 23D 0.000001697 0.52118 43.5331
302 1ZY5 ANP 0.000007214 0.50577 43.5644
303 4I6H 1C8 0.00002821 0.48806 43.8312
304 4XV1 904 0.0000006027 0.59642 43.8356
305 3PE2 E1B 0.0000002103 0.63585 43.9169
306 3ZRM ZRM 0.000001893 0.53161 43.956
307 4XLI 1N1 0.00000179 0.52535 44.0299
308 2YAK OSV 0.00000001627 0.6595 44.2105
309 2JLD AG1 0.000000005366 0.6879 44.2308
310 4NM5 ADP 0.0003908 0.48869 44.2308
311 4NST ADP 0.000000006281 0.63492 44.4444
312 4C2W ANP 0.00000000655 0.59157 44.4444
313 3KN5 ANP 0.00000004165 0.5756 44.9231
314 4L3L 5FI 0.0000003921 0.59859 45.0658
315 5X8I SQZ 0.0000000004122 0.68072 45.0867
316 4KS7 X4Z 0.0000008729 0.54418 45.2055
317 5EFQ ADP 0.000000002818 0.64845 45.245
318 3F7Z 34O 0.0000001014 0.58598 45.7143
319 3OFM 4B0 0.0000001703 0.54719 45.7143
320 4CQE CQE 0.000006681 0.52905 46.0432
321 4IJP 1EH 0.000000008782 0.64832 46.0894
322 2XK9 XK9 0.0002248 0.5183 46.2733
323 5G1X ADP 0.0000000002628 0.67707 46.3158
324 5L8L ADP 0.00000001205 0.58451 46.3158
325 5DEY 59T 0.000002751 0.59181 46.4646
326 4TWP AXI 0.000001356 0.59698 46.4945
327 2X4Z X4Z 0.000002752 0.56877 46.6216
328 5LXM ADP 0.0000000001418 0.68596 46.6431
329 5JZJ AN2 0.000000000003307 0.74905 47.138
330 1Q8Y ADP 0.0000000004846 0.70152 47.2527
331 1Q8Y ADE 0.0000001244 0.52884 47.2527
332 5EYK 5U5 0.0000007604 0.58158 47.4638
333 3GC0 AMP 0.000002858 0.50493 47.7204
334 5EW9 5VC 0.00001611 0.58822 48.3395
335 2WEI VGG 0.0000002032 0.55188 48.4321
336 3E5A VX6 0.000002227 0.51153 49.2537
337 4AUA 4AU 0.0000007416 0.54516 49.8371
338 3LXN MI1 0.0000000006485 0.69617 50
339 3BU5 ATP 0.00000001202 0.62276 50
340 4GJ3 0XP 0.0000001303 0.62189 50
341 3EKK GS2 0.0000004288 0.60861 50
342 4Y93 746 0.0000004732 0.58582 50
343 5U6C 7YS 0.000001583 0.55565 50
344 5LXT ACP 0.0002815 0.46199 50
Pocket No.: 3; Query (leader) PDB : 4UX9; Ligand: ANP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4ux9.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4UX9; Ligand: ANP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4ux9.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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