Receptor
PDB id Resolution Class Description Source Keywords
4UFM 2.4 Å EC: 3.2.1.46 MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH 1-DEOXY-GALACTO-NO DGJ MUS MUSCULUS HYDROLASE COMPLEX LYSOSOME
Ref.: AZASUGAR INHIBITORS AS PHARMACOLOGICAL CHAPERONES F DISEASE. CHEM.SCI. V. 6 3075 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DGJ A:1001;
 Valid;
 none;
 Ki = 190 uM
163.172 C6 H13 N O4 C1[C@...
NAG A:1387;
 Invalid;
 none;
 submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG D:1;
C:1;
B:1;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
408.404 n/a O=C(N...
CA A:3669;
 Part of Protein;
 none;
 submit data
40.078 Ca [Ca+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4UFH 2.16 Å EC: 3.2.1.46 MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH ISO-GALACTO-FAGOMI MUS MUSCULUS HYDROLASE GLYCOSYL HYDROLASE COMPLEX LYSOSOME
Ref.: AZASUGAR INHIBITORS AS PHARMACOLOGICAL CHAPERONES F DISEASE. CHEM.SCI. V. 6 3075 2015
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3ZR6 - GAL C6 H12 O6 C([C@@H]1[....
2 4CCE - GAL C6 H12 O6 C([C@@H]1[....
3 4UFK Ki = 130 uM LDU C5 H11 N O3 C1[C@H]([C....
4 4CCC - 147 C12 H15 N O8 c1cc(ccc1[....
5 4UFM Ki = 190 uM DGJ C6 H13 N O4 C1[C@@H]([....
6 4UFJ Ki = 52 uM IF7 C6 H11 N O4 C1[C@@H]([....
7 4UFI Ki = 630 nM AGK C5 H12 N2 O3 C1[C@H]([C....
8 4UFL Ki = 2.3 mM DZX C8 H15 N O3 C1C[C@H]2[....
9 4UFH Ki = 380 nM GIF C6 H13 N O3 C1[C@@H]([....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3ZR6 - GAL C6 H12 O6 C([C@@H]1[....
2 4CCE - GAL C6 H12 O6 C([C@@H]1[....
3 4UFK Ki = 130 uM LDU C5 H11 N O3 C1[C@H]([C....
4 4CCC - 147 C12 H15 N O8 c1cc(ccc1[....
5 4UFM Ki = 190 uM DGJ C6 H13 N O4 C1[C@@H]([....
6 4UFJ Ki = 52 uM IF7 C6 H11 N O4 C1[C@@H]([....
7 4UFI Ki = 630 nM AGK C5 H12 N2 O3 C1[C@H]([C....
8 4UFL Ki = 2.3 mM DZX C8 H15 N O3 C1C[C@H]2[....
9 4UFH Ki = 380 nM GIF C6 H13 N O3 C1[C@@H]([....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3ZR6 - GAL C6 H12 O6 C([C@@H]1[....
2 4CCE - GAL C6 H12 O6 C([C@@H]1[....
3 4UFK Ki = 130 uM LDU C5 H11 N O3 C1[C@H]([C....
4 4CCC - 147 C12 H15 N O8 c1cc(ccc1[....
5 4UFM Ki = 190 uM DGJ C6 H13 N O4 C1[C@@H]([....
6 4UFJ Ki = 52 uM IF7 C6 H11 N O4 C1[C@@H]([....
7 4UFI Ki = 630 nM AGK C5 H12 N2 O3 C1[C@H]([C....
8 4UFL Ki = 2.3 mM DZX C8 H15 N O3 C1C[C@H]2[....
9 4UFH Ki = 380 nM GIF C6 H13 N O3 C1[C@@H]([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: DGJ; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 DMJ 1 1
2 DGJ 1 1
3 NOJ 1 1
4 EDG 0.703704 0.853659
5 IMR 0.703704 0.853659
6 LDU 0.703704 0.853659
7 1AB 0.703704 0.853659
8 HQ6 0.454545 0.765957
Similar Ligands (3D)
Ligand no: 1; Ligand: DGJ; Similar ligands found: 1268
No: Ligand Similarity coefficient
1 TZL 1.0000
2 GAL 0.9997
3 IF7 0.9984
4 GLA 0.9829
5 X6X 0.9761
6 2FG 0.9734
7 2H5 0.9729
8 GAF 0.9721
9 149 0.9720
10 GIF 0.9700
11 0MK 0.9698
12 MBG 0.9696
13 AGK 0.9680
14 HX3 0.9668
15 1GN 0.9663
16 FDK 0.9624
17 FH2 0.9619
18 YIO 0.9616
19 GLC 0.9613
20 KOJ 0.9612
21 ASO 0.9559
22 FCA 0.9556
23 G2F 0.9542
24 INO 0.9527
25 DHB 0.9522
26 4NC 0.9514
27 SOE 0.9509
28 ADA 0.9506
29 IFL 0.9506
30 EMZ 0.9500
31 3XX 0.9494
32 V55 0.9493
33 4AA 0.9492
34 AHR 0.9491
35 NOY 0.9488
36 4XR 0.9486
37 LCN 0.9485
38 GTR 0.9481
39 93K 0.9475
40 FCB 0.9454
41 FYU 0.9453
42 CHB 0.9452
43 2XX 0.9451
44 HBA 0.9451
45 XYP 0.9445
46 4VP 0.9443
47 RM4 0.9442
48 BZ3 0.9433
49 IHB 0.9429
50 7D2 0.9426
51 9TW 0.9426
52 MYJ 0.9423
53 WBU 0.9423
54 URF 0.9423
55 2HO 0.9422
56 XX2 0.9420
57 P9P 0.9419
58 BGC 0.9418
59 GCS 0.9415
60 G3F 0.9412
61 HMH 0.9412
62 RIB 0.9409
63 5OB 0.9406
64 15L 0.9405
65 2GS 0.9404
66 TH7 0.9402
67 RNS 0.9393
68 2A9 0.9392
69 Z6J 0.9392
70 G4D 0.9390
71 MCT 0.9389
72 XYS 0.9388
73 JZ2 0.9383
74 4CL 0.9383
75 AFR 0.9381
76 LXC 0.9378
77 I3A 0.9376
78 ARW 0.9373
79 QSB 0.9364
80 MAN 0.9361
81 Q88 0.9359
82 LDP 0.9358
83 FUC 0.9354
84 GLF 0.9351
85 F0J 0.9349
86 XYD 0.9348
87 XBZ 0.9345
88 DZX 0.9345
89 4HO 0.9344
90 DFB 0.9344
91 SRT 0.9342
92 XLS 0.9341
93 82I 0.9340
94 8H8 0.9340
95 DBH 0.9338
96 2AC 0.9337
97 4JJ 0.9337
98 MMA 0.9336
99 EHM 0.9335
100 MZG 0.9334
101 MWJ 0.9333
102 CWM 0.9330
103 34A 0.9326
104 BR9 0.9326
105 EUG 0.9326
106 NPO 0.9325
107 MNM 0.9324
108 ARB 0.9324
109 PAB 0.9324
110 SYV 0.9323
111 4M4 0.9321
112 3RK 0.9321
113 XIY 0.9320
114 27Y 0.9317
115 5MH 0.9315
116 3HA 0.9315
117 4HM 0.9314
118 NNO 0.9313
119 ES0 0.9312
120 5JC 0.9310
121 8WO 0.9308
122 8S0 0.9307
123 PHB 0.9305
124 PA1 0.9303
125 FHB 0.9300
126 ZB1 0.9297
127 LGC 0.9297
128 QOS 0.9292
129 A1U 0.9292
130 1MC 0.9292
131 BDP 0.9292
132 4A3 0.9291
133 2MP 0.9291
134 3HM 0.9289
135 6LW 0.9287
136 VNL 0.9277
137 BDF 0.9276
138 JLZ 0.9275
139 717 0.9275
140 TM7 0.9274
141 1P8 0.9274
142 1M2 0.9272
143 4ZE 0.9271
144 TH0 0.9271
145 ASC 0.9270
146 ICP 0.9266
147 PYD 0.9266
148 5XC 0.9266
149 95Z 0.9265
150 GDE 0.9265
151 23A 0.9264
152 BZX 0.9264
153 RAT 0.9263
154 FA1 0.9262
155 3IT 0.9262
156 RUU 0.9262
157 ZXD 0.9260
158 3F0 0.9259
159 DHK 0.9258
160 3HB 0.9258
161 CN0 0.9257
162 MWM 0.9256
163 HT4 0.9254
164 IFM 0.9254
165 3ID 0.9253
166 94B 0.9253
167 FPY 0.9253
168 43M 0.9252
169 ZZT 0.9250
170 T6C 0.9250
171 TDR 0.9249
172 2YU 0.9246
173 B57 0.9246
174 HHA 0.9244
175 GOO 0.9242
176 BSX 0.9242
177 2MI 0.9241
178 MR1 0.9241
179 3NT 0.9241
180 TLA 0.9239
181 3M0 0.9237
182 URC 0.9237
183 DFU 0.9236
184 ALL 0.9235
185 FA0 0.9235
186 P3K 0.9234
187 3DM 0.9233
188 948 0.9232
189 OXZ 0.9230
190 DHS 0.9230
191 RIP 0.9229
192 AX7 0.9228
193 0R0 0.9228
194 P92 0.9227
195 PBZ 0.9227
196 XQ0 0.9225
197 5CU 0.9222
198 AH8 0.9221
199 4M0 0.9221
200 Y8I 0.9219
201 HBD 0.9219
202 SF9 0.9218
203 HYA 0.9218
204 CXF 0.9218
205 JAE 0.9217
206 4XV 0.9216
207 261 0.9216
208 JZ3 0.9214
209 270 0.9213
210 5UC 0.9213
211 8TX 0.9213
212 AMG 0.9212
213 XM0 0.9212
214 XYL 0.9211
215 RB5 0.9211
216 ES2 0.9211
217 HMU 0.9210
218 LYL 0.9209
219 GAB 0.9209
220 4JO 0.9208
221 7MH 0.9208
222 DOB 0.9208
223 C2A 0.9208
224 IDH 0.9207
225 OVV 0.9206
226 F31 0.9204
227 AC6 0.9203
228 ABV 0.9202
229 2EC 0.9202
230 YHO 0.9202
231 PZI 0.9202
232 42J 0.9201
233 6PC 0.9201
234 FP1 0.9196
235 GIV 0.9195
236 RAM 0.9195
237 8WT 0.9194
238 FUL 0.9194
239 FAN 0.9194
240 6AI 0.9192
241 FBA 0.9192
242 TLD 0.9190
243 4CS 0.9190
244 CGB 0.9190
245 GXL 0.9187
246 ABE 0.9186
247 GTQ 0.9186
248 DMD 0.9184
249 0P6 0.9184
250 KJY 0.9183
251 AZF 0.9182
252 1P7 0.9180
253 3DO 0.9179
254 3Z7 0.9179
255 QSH 0.9178
256 FPI 0.9178
257 YTB 0.9177
258 FUB 0.9177
259 BE2 0.9176
260 ES9 0.9175
261 JIF 0.9175
262 LRH 0.9174
263 ET2 0.9171
264 32O 0.9170
265 M1A 0.9170
266 4XS 0.9169
267 67N 0.9169
268 HIS 0.9169
269 B53 0.9167
270 HPA 0.9166
271 11S 0.9164
272 TAR 0.9164
273 1LQ 0.9163
274 FUF 0.9162
275 Z82 0.9161
276 C2B 0.9160
277 YRL 0.9160
278 XUL 0.9157
279 H8N 0.9155
280 AMC 0.9155
281 DIG 0.9154
282 24B 0.9154
283 53C 0.9154
284 KBG 0.9153
285 7N0 0.9153
286 H76 0.9152
287 ISD 0.9152
288 5MI 0.9152
289 SVJ 0.9152
290 R2B 0.9151
291 1DW 0.9150
292 7HQ 0.9150
293 NSP 0.9149
294 IFP 0.9149
295 ADE 0.9149
296 SYN 0.9148
297 GYE 0.9147
298 SKM 0.9146
299 TBP 0.9146
300 6RQ 0.9145
301 RBL 0.9144
302 INS 0.9143
303 X0V 0.9143
304 EVA 0.9143
305 1P3 0.9142
306 N8P 0.9142
307 3U4 0.9141
308 7B4 0.9140
309 03V 0.9139
310 5MB 0.9139
311 5QX 0.9139
312 XAN 0.9138
313 J9T 0.9138
314 1PT 0.9137
315 JB5 0.9136
316 BHA 0.9136
317 A7W 0.9135
318 4P5 0.9135
319 286 0.9134
320 FK1 0.9133
321 2CQ 0.9132
322 3SK 0.9132
323 RPQ 0.9130
324 FBB 0.9130
325 H4N 0.9130
326 5NU 0.9130
327 0HO 0.9130
328 BHO 0.9130
329 RM1 0.9129
330 ES5 0.9129
331 5B1 0.9129
332 NK 0.9129
333 14O 0.9128
334 5VM 0.9128
335 NMJ 0.9128
336 BTE 0.9127
337 FE DB1 0.9125
338 CTL 0.9125
339 VOH 0.9125
340 URQ 0.9124
341 5H1 0.9123
342 F60 0.9123
343 COU 0.9122
344 CLW 0.9121
345 2D0 0.9121
346 SAL 0.9121
347 P72 0.9120
348 K2T 0.9119
349 BMA 0.9119
350 3A9 0.9119
351 OAA 0.9119
352 IUR 0.9118
353 MRW 0.9117
354 3PF 0.9117
355 35C 0.9116
356 ARA 0.9116
357 7W4 0.9115
358 3MG 0.9115
359 F81 0.9115
360 R8A 0.9115
361 G6D 0.9114
362 DIN 0.9112
363 E7Z 0.9112
364 3Z8 0.9112
365 7HP 0.9111
366 36R 0.9110
367 3AB 0.9110
368 HBX 0.9109
369 L99 0.9107
370 4FS 0.9106
371 9RW 0.9106
372 4JL 0.9105
373 PSJ 0.9104
374 TNE 0.9104
375 VGD 0.9102
376 2LP 0.9102
377 EKZ 0.9101
378 42A 0.9100
379 F9Y 0.9100
380 H7Y 0.9100
381 FRU 0.9098
382 8ZE 0.9098
383 2AQ 0.9098
384 MSN 0.9098
385 5RG 0.9098
386 G3E 0.9097
387 1F1 0.9097
388 2BG 0.9096
389 LZM 0.9096
390 BEZ 0.9096
391 K5W 0.9096
392 HXX 0.9096
393 3BZ 0.9095
394 3NY 0.9094
395 ISN 0.9093
396 ICO 0.9093
397 5WV 0.9092
398 ES7 0.9091
399 NIZ 0.9091
400 BEN 0.9091
401 64K 0.9090
402 GZL 0.9090
403 0HN 0.9089
404 WOO 0.9088
405 PYG 0.9088
406 SHA 0.9087
407 MLT 0.9087
408 JFJ 0.9086
409 ILE 0.9085
410 MZW 0.9085
411 25W 0.9084
412 4WL 0.9084
413 FUD 0.9084
414 GLU 0.9084
415 H42 0.9083
416 GUN 0.9083
417 VNJ 0.9083
418 6NT 0.9081
419 ES6 0.9080
420 FGZ 0.9079
421 4JQ 0.9077
422 KUF 0.9076
423 LNR 0.9075
424 2K4 0.9075
425 NCA 0.9074
426 4MA 0.9073
427 KJU 0.9071
428 9PY 0.9071
429 0TR 0.9070
430 SS2 0.9070
431 2ZM 0.9069
432 4FA 0.9068
433 NDH 0.9067
434 QIC 0.9067
435 BML 0.9067
436 UEG 0.9065
437 ABN 0.9065
438 IDM 0.9065
439 KKN 0.9064
440 PBC 0.9064
441 FDB 0.9063
442 I1N 0.9063
443 NIO 0.9063
444 AEH 0.9062
445 JZ7 0.9061
446 3OC 0.9061
447 F05 0.9061
448 4JM 0.9060
449 54G 0.9060
450 PTO 0.9060
451 PNZ 0.9060
452 4JT 0.9059
453 OCH 0.9059
454 SE2 0.9059
455 BAM 0.9059
456 NBZ 0.9059
457 M1E 0.9059
458 150 0.9058
459 2CK 0.9058
460 GCU 0.9058
461 SWA 0.9058
462 5RO 0.9058
463 8EZ 0.9056
464 3FH 0.9052
465 4CH 0.9051
466 1WG 0.9050
467 HQD 0.9050
468 UNU 0.9050
469 CRN 0.9050
470 ISZ 0.9049
471 RHU 0.9049
472 JND 0.9048
473 1Y6 0.9048
474 IP0 0.9048
475 8GC 0.9047
476 8NY 0.9047
477 AMH 0.9047
478 F4Z 0.9047
479 CWS 0.9047
480 ORO 0.9047
481 CFI 0.9046
482 SR1 0.9045
483 ADZ 0.9045
484 75K 0.9043
485 45C 0.9043
486 JBK 0.9042
487 4ZC 0.9042
488 5QY 0.9042
489 5HN 0.9041
490 9DG 0.9041
491 BTY 0.9040
492 J5I 0.9039
493 ZWZ 0.9039
494 9TZ 0.9039
495 SF6 0.9038
496 SVD 0.9038
497 86J 0.9038
498 ASN 0.9038
499 J9W 0.9037
500 MET 0.9037
501 DQA 0.9036
502 JPZ 0.9035
503 D48 0.9035
504 LT2 0.9035
505 24W 0.9035
506 BZ2 0.9034
507 RBJ 0.9032
508 IV2 0.9032
509 12Q 0.9032
510 G8M 0.9032
511 IJZ 0.9031
512 N2I 0.9030
513 069 0.9030
514 3DY 0.9030
515 RNT 0.9029
516 TC7 0.9029
517 PZM 0.9029
518 DOR 0.9029
519 BDR 0.9027
520 SHG 0.9025
521 4JU 0.9025
522 5M0 0.9024
523 2HQ 0.9023
524 GXY 0.9023
525 ITN 0.9023
526 ABI 0.9022
527 PZA 0.9022
528 1SQ 0.9020
529 5SG 0.9020
530 SOR 0.9020
531 3V4 0.9020
532 KJH 0.9018
533 XXR 0.9017
534 6M4 0.9017
535 DHR 0.9016
536 6NI 0.9016
537 BCU 0.9015
538 PEL 0.9014
539 JA8 0.9013
540 JFD 0.9013
541 14J 0.9013
542 5IQ 0.9011
543 JZ1 0.9010
544 OXC 0.9010
545 4SX 0.9009
546 7W1 0.9008
547 JZ4 0.9008
548 SW7 0.9008
549 PFB 0.9008
550 PHU 0.9008
551 HQY 0.9007
552 LMR 0.9007
553 N5J 0.9006
554 1LN 0.9004
555 AEF 0.9004
556 10L 0.9004
557 7A8 0.9004
558 MZB 0.9003
559 S76 0.9003
560 FBV 0.9001
561 R8S 0.9000
562 5MK 0.9000
563 FX1 0.8999
564 1NP 0.8999
565 B24 0.8999
566 K6H 0.8998
567 MFU 0.8998
568 WCE 0.8997
569 FA3 0.8997
570 SJ5 0.8996
571 1LM 0.8996
572 KPL 0.8996
573 41K 0.8995
574 4ZA 0.8995
575 JTH 0.8995
576 PYJ 0.8995
577 G5V 0.8995
578 4HC 0.8994
579 CAX 0.8993
580 51R 0.8993
581 O72 0.8992
582 HY1 0.8992
583 5RN 0.8992
584 B55 0.8991
585 8CM 0.8991
586 GCB 0.8991
587 JKE 0.8991
588 XXG 0.8990
589 QBK 0.8990
590 PXM 0.8989
591 4YS 0.8988
592 KTA 0.8988
593 6HQ 0.8987
594 LFR 0.8986
595 RSO 0.8986
596 TSS 0.8986
597 2AL 0.8986
598 SEJ 0.8985
599 TEP 0.8985
600 CRS 0.8985
601 MFB 0.8984
602 F5B 0.8983
603 PAF 0.8982
604 ES1 0.8981
605 GLT 0.8980
606 6F0 0.8980
607 RP7 0.8980
608 9HX 0.8979
609 OHP 0.8979
610 TTL 0.8979
611 EOL 0.8977
612 QUZ 0.8977
613 DIE 0.8977
614 1MR 0.8977
615 KT7 0.8976
616 FOT 0.8975
617 9DA 0.8974
618 MS9 0.8974
619 282 0.8973
620 B62 0.8973
621 FBT 0.8973
622 GTL 0.8972
623 4FH 0.8972
624 0TU 0.8971
625 DHY 0.8971
626 BNS 0.8971
627 JBH 0.8969
628 5Q0 0.8969
629 PYF 0.8969
630 UAN 0.8968
631 HGQ 0.8968
632 4RW 0.8967
633 NPY 0.8967
634 HH5 0.8967
635 FCR 0.8967
636 PEA 0.8966
637 NK2 0.8966
638 2MH 0.8965
639 4YO 0.8965
640 PRY 0.8964
641 YH7 0.8964
642 3SL 0.8964
643 7WA 0.8963
644 2A7 0.8962
645 PXL 0.8962
646 329 0.8962
647 6M9 0.8961
648 I2M 0.8961
649 ZZ3 0.8961
650 AZA 0.8960
651 JAW 0.8960
652 4NG 0.8957
653 SKG 0.8957
654 APY 0.8957
655 7MU 0.8956
656 4HS 0.8956
657 4Z4 0.8955
658 F9P 0.8955
659 XAZ 0.8954
660 D1X 0.8954
661 LKA 0.8954
662 9MG 0.8954
663 6MP 0.8953
664 ORN 0.8951
665 826 0.8951
666 Q6T 0.8951
667 8OZ 0.8951
668 CTS 0.8950
669 AHB 0.8949
670 OHG 0.8949
671 L3Q 0.8947
672 BRT 0.8946
673 5JQ 0.8946
674 FB1 0.8946
675 1XX 0.8945
676 ESP 0.8942
677 ANN 0.8942
678 TZE 0.8941
679 HIO 0.8941
680 0W8 0.8941
681 MWP 0.8940
682 6CS 0.8940
683 TYL 0.8940
684 34V 0.8939
685 5NI 0.8939
686 MQN 0.8938
687 NBE 0.8937
688 SWD 0.8935
689 FQI 0.8935
690 DQU 0.8934
691 IUP 0.8933
692 NTN 0.8933
693 DS0 0.8931
694 ODO 0.8931
695 4P0 0.8930
696 0RW 0.8929
697 R1X 0.8929
698 IPB 0.8929
699 GRE 0.8929
700 PY7 0.8928
701 5JL 0.8928
702 XXP 0.8926
703 TWO 0.8926
704 HQT 0.8925
705 GCO 0.8925
706 CEE 0.8924
707 HYP 0.8924
708 2DR 0.8923
709 PAC 0.8923
710 URA 0.8923
711 5GU 0.8922
712 K97 0.8922
713 5DI 0.8920
714 AZ9 0.8920
715 ICB 0.8920
716 OVM 0.8919
717 YCP 0.8919
718 3WA 0.8917
719 9EW 0.8916
720 GOX 0.8914
721 45L 0.8914
722 MXN 0.8913
723 AKH 0.8913
724 IOL 0.8912
725 B0D 0.8911
726 EV0 0.8911
727 268 0.8910
728 HZP 0.8910
729 26D 0.8909
730 1XM 0.8908
731 SKA 0.8907
732 THE 0.8906
733 98J 0.8906
734 AC0 0.8905
735 TPA 0.8905
736 VGL 0.8905
737 FEH 0.8904
738 R9S 0.8904
739 IGA 0.8903
740 9CL 0.8902
741 DBX 0.8902
742 HLR 0.8901
743 97T 0.8901
744 SVN 0.8900
745 SNE 0.8899
746 AL0 0.8898
747 2FY 0.8898
748 KDV 0.8898
749 4PW 0.8898
750 0CU 0.8896
751 C2U 0.8896
752 A2F 0.8893
753 4JN 0.8893
754 DEN 0.8892
755 XX3 0.8892
756 8IG 0.8892
757 R9Y 0.8892
758 42C 0.8892
759 JZ9 0.8892
760 174 0.8889
761 VAH 0.8888
762 UY7 0.8887
763 KP6 0.8886
764 XRG 0.8886
765 EXO 0.8886
766 275 0.8885
767 M58 0.8885
768 XQG 0.8884
769 293 0.8884
770 BOA 0.8883
771 0FN 0.8883
772 4SV 0.8882
773 3R6 0.8882
774 7ME 0.8881
775 A13 0.8881
776 DEE 0.8880
777 OTW 0.8879
778 R8V 0.8878
779 7WG 0.8878
780 UFV 0.8878
781 GJZ 0.8877
782 AW5 0.8877
783 URP 0.8877
784 FBM 0.8875
785 GLN 0.8875
786 VXX 0.8874
787 PRZ 0.8873
788 6GU 0.8872
789 1AL 0.8871
790 ES4 0.8870
791 6AP 0.8870
792 GVH 0.8869
793 EA1 0.8869
794 0JD 0.8869
795 IND 0.8868
796 2HU 0.8867
797 HH8 0.8866
798 GYP 0.8864
799 7VJ 0.8864
800 FHN 0.8863
801 141 0.8863
802 PE0 0.8863
803 PXY 0.8863
804 PCR 0.8862
805 PRF 0.8862
806 6ME 0.8862
807 40E 0.8862
808 LZ1 0.8860
809 BZI 0.8860
810 HEW 0.8860
811 OTR 0.8860
812 4XH 0.8859
813 QX2 0.8858
814 NDM 0.8858
815 1U6 0.8858
816 HDA 0.8858
817 QX4 0.8858
818 J9Q 0.8858
819 PM6 0.8857
820 M4T 0.8857
821 290 0.8857
822 M1Q 0.8857
823 TSU 0.8857
824 PMB 0.8857
825 4JP 0.8856
826 5AC 0.8856
827 HDH 0.8855
828 ASP 0.8855
829 HHR 0.8855
830 0R1 0.8854
831 3C4 0.8854
832 TAG 0.8852
833 QSC 0.8852
834 F12 0.8852
835 7VS 0.8851
836 7WR 0.8848
837 BCP 0.8847
838 MEW 0.8846
839 LG4 0.8846
840 BP9 0.8846
841 HPY 0.8846
842 BZF 0.8845
843 AZG 0.8845
844 Q24 0.8845
845 MPI 0.8844
846 M0W 0.8844
847 PBE 0.8843
848 CAM 0.8843
849 PLQ 0.8842
850 3MB 0.8841
851 E5X 0.8841
852 1DJ 0.8840
853 MA3 0.8839
854 0LH 0.8839
855 DX4 0.8839
856 0N7 0.8839
857 XHP 0.8838
858 6M1 0.8838
859 MO8 0.8837
860 HA7 0.8837
861 B2J 0.8836
862 7CZ 0.8836
863 BP1 0.8836
864 92K 0.8836
865 12T 0.8836
866 N8Y 0.8835
867 2FT 0.8834
868 271 0.8834
869 PCA 0.8834
870 AZ8 0.8833
871 15N 0.8833
872 SS1 0.8833
873 ESX 0.8833
874 TM4 0.8832
875 HQE 0.8831
876 JB8 0.8831
877 O7U 0.8831
878 GLY PRO 0.8830
879 CFP 0.8830
880 RSF 0.8830
881 SAN 0.8830
882 ICF 0.8829
883 AOS 0.8829
884 HDL 0.8829
885 JDN 0.8829
886 MVL 0.8829
887 23J 0.8829
888 258 0.8828
889 2AS 0.8828
890 IPZ 0.8828
891 SDD 0.8827
892 QWW 0.8827
893 NGT 0.8826
894 NGW 0.8826
895 M6N 0.8826
896 ISE 0.8826
897 JZ5 0.8826
898 B3R 0.8825
899 OW4 0.8825
900 44V 0.8824
901 H3M 0.8823
902 25R 0.8823
903 1WD 0.8822
904 7NI 0.8821
905 2PG 0.8821
906 C2Y 0.8821
907 3CE 0.8820
908 OMD 0.8820
909 M0Q 0.8820
910 PSV 0.8819
911 HJP 0.8819
912 34D 0.8819
913 SX1 0.8819
914 DNF 0.8819
915 HC4 0.8819
916 GLL 0.8819
917 I1E 0.8817
918 ESI 0.8817
919 3BU 0.8816
920 FPN 0.8816
921 DA1 0.8816
922 SPV 0.8816
923 PEP 0.8816
924 AS3 0.8815
925 TFU 0.8815
926 HHQ 0.8814
927 SFU 0.8813
928 M5K 0.8813
929 44W 0.8813
930 GAG 0.8813
931 AKG 0.8812
932 NEQ 0.8812
933 6MH 0.8810
934 JXN 0.8809
935 6KX 0.8809
936 M3T 0.8808
937 PQ0 0.8807
938 TGX 0.8807
939 9X7 0.8807
940 BE7 0.8806
941 CWJ 0.8806
942 6UA 0.8806
943 MEV 0.8805
944 SN4 0.8805
945 3CH 0.8804
946 AQO 0.8804
947 E7S 0.8804
948 DIU 0.8804
949 94W 0.8803
950 OK7 0.8802
951 GIO 0.8802
952 MRZ 0.8801
953 QY9 0.8801
954 KDF 0.8801
955 4H2 0.8800
956 CIG 0.8800
957 0CT 0.8799
958 15E 0.8799
959 AUD 0.8797
960 SEP 0.8796
961 284 0.8796
962 9KH 0.8795
963 K32 0.8794
964 ZBT 0.8793
965 KBB 0.8792
966 6FZ 0.8791
967 M6W 0.8791
968 285 0.8790
969 3AL 0.8789
970 FPK 0.8789
971 MUA 0.8789
972 MNN 0.8789
973 9FL 0.8788
974 H62 0.8787
975 SYA 0.8787
976 BPN 0.8787
977 INE 0.8787
978 UNC 0.8786
979 APZ 0.8786
980 KIB 0.8786
981 SMN 0.8786
982 ECE 0.8784
983 260 0.8782
984 OEM 0.8782
985 PHE 0.8782
986 JBE 0.8781
987 IT9 0.8781
988 GBD 0.8781
989 HTP 0.8781
990 HLZ 0.8781
991 39A 0.8780
992 2C9 0.8780
993 DUB 0.8780
994 EYK 0.8780
995 5WX 0.8780
996 2CM 0.8779
997 9R5 0.8778
998 CAQ 0.8778
999 PQK 0.8777
1000 L14 0.8777
1001 7WV 0.8775
1002 BEW 0.8775
1003 51F 0.8774
1004 ICC 0.8773
1005 2MY 0.8773
1006 NGO 0.8773
1007 47J 0.8773
1008 QWN 0.8772
1009 XCZ 0.8771
1010 449 0.8771
1011 MBD 0.8770
1012 TMH 0.8769
1013 X05 0.8768
1014 DAS 0.8768
1015 AAS 0.8767
1016 9ZE 0.8766
1017 3ZQ 0.8766
1018 BVF 0.8765
1019 1DV 0.8765
1020 IT2 0.8764
1021 PH2 0.8764
1022 REL 0.8763
1023 VK3 0.8763
1024 3HP 0.8762
1025 AJ2 0.8762
1026 4NM 0.8762
1027 23W 0.8761
1028 HQ9 0.8760
1029 GMN 0.8760
1030 CIT 0.8760
1031 RCO 0.8759
1032 NFM 0.8759
1033 2ZV 0.8759
1034 SYG 0.8759
1035 259 0.8758
1036 DRL 0.8757
1037 T9G 0.8757
1038 2HC 0.8756
1039 3MC 0.8755
1040 NK1 0.8755
1041 BNF 0.8754
1042 HQJ 0.8754
1043 MVN 0.8753
1044 S24 0.8752
1045 GNL 0.8751
1046 NSG 0.8751
1047 4ME 0.8751
1048 0FO 0.8751
1049 40O 0.8751
1050 K17 0.8751
1051 A65 0.8750
1052 DQN 0.8750
1053 LG5 0.8749
1054 IPM 0.8748
1055 9YT 0.8748
1056 M2K 0.8747
1057 BEA 0.8747
1058 9FE 0.8746
1059 5CL 0.8745
1060 CIZ 0.8744
1061 6VD 0.8744
1062 4MU 0.8742
1063 9YL 0.8741
1064 264 0.8740
1065 AX3 0.8739
1066 92P 0.8739
1067 FB2 0.8739
1068 X09 0.8738
1069 MRY 0.8737
1070 FBS 0.8736
1071 DBJ 0.8736
1072 LG3 0.8735
1073 EQT 0.8735
1074 PKU 0.8735
1075 OVP 0.8734
1076 UFO 0.8734
1077 GGL 0.8733
1078 FLA 0.8733
1079 N7P 0.8732
1080 MUC 0.8732
1081 UNJ 0.8732
1082 MIG 0.8730
1083 3FA 0.8730
1084 4BZ 0.8730
1085 UGC 0.8729
1086 4J8 0.8728
1087 209 0.8726
1088 DE5 0.8726
1089 8GF 0.8725
1090 RMN 0.8723
1091 SXS 0.8722
1092 8NB 0.8722
1093 HSE 0.8721
1094 H33 0.8720
1095 1XN 0.8718
1096 HY3 0.8717
1097 HA5 0.8717
1098 173 0.8717
1099 YPN 0.8716
1100 URS 0.8716
1101 J6W 0.8715
1102 GIM 0.8715
1103 HZQ 0.8713
1104 0W1 0.8713
1105 KTW 0.8713
1106 M1H 0.8711
1107 5FN 0.8710
1108 94N 0.8710
1109 0F9 0.8710
1110 FBW 0.8709
1111 NTZ 0.8708
1112 MPV 0.8708
1113 DHQ 0.8707
1114 DUC 0.8704
1115 32X 0.8704
1116 KMT 0.8704
1117 YSO 0.8704
1118 428 0.8703
1119 MT0 0.8701
1120 TTY 0.8701
1121 I4B 0.8700
1122 AMS 0.8700
1123 3MH 0.8699
1124 2CL 0.8699
1125 FFP 0.8698
1126 OXQ 0.8698
1127 2ZX 0.8696
1128 FLM 0.8695
1129 12M 0.8695
1130 AEG 0.8694
1131 60P 0.8693
1132 263 0.8692
1133 36E 0.8689
1134 II6 0.8687
1135 2ZQ 0.8687
1136 54D 0.8686
1137 495 0.8685
1138 LYS 0.8685
1139 GTZ 0.8684
1140 GT0 0.8683
1141 GJS 0.8682
1142 GRO 0.8679
1143 FSG 0.8679
1144 QXW 0.8679
1145 4TU 0.8678
1146 680 0.8677
1147 52C 0.8675
1148 CYT 0.8672
1149 TEO 0.8672
1150 A29 0.8671
1151 PYQ 0.8671
1152 L5V 0.8670
1153 NYL 0.8669
1154 SLS 0.8669
1155 FSW 0.8669
1156 NLE 0.8668
1157 4HP 0.8668
1158 P4B 0.8667
1159 7MK 0.8666
1160 KDG 0.8666
1161 OA3 0.8665
1162 TIU 0.8665
1163 JF2 0.8664
1164 ARP 0.8661
1165 3MA 0.8660
1166 ADK 0.8660
1167 PRA 0.8660
1168 AI2 0.8659
1169 PBA 0.8659
1170 BK9 0.8659
1171 APS 0.8659
1172 5LA 0.8658
1173 NVA 0.8656
1174 8W9 0.8656
1175 JBQ 0.8655
1176 NQ 0.8651
1177 KYD 0.8651
1178 2AK 0.8650
1179 LSA 0.8650
1180 N2Z 0.8648
1181 4BY 0.8646
1182 57O 0.8645
1183 5WY 0.8645
1184 SRO 0.8645
1185 K34 0.8643
1186 XBT 0.8642
1187 K3Q 0.8642
1188 2MN 0.8634
1189 HHH 0.8634
1190 KIA 0.8633
1191 2FQ 0.8633
1192 N3W 0.8633
1193 DTL 0.8633
1194 CFF 0.8631
1195 YTX 0.8629
1196 7ZE 0.8629
1197 13P 0.8628
1198 CAH 0.8627
1199 9TY 0.8627
1200 AC5 0.8626
1201 SIN 0.8624
1202 FLC 0.8624
1203 IOM 0.8622
1204 SOL 0.8621
1205 ZZZ 0.8620
1206 5ZE 0.8619
1207 COI 0.8619
1208 5WU 0.8618
1209 QAS 0.8618
1210 DJN 0.8618
1211 9KT 0.8616
1212 6JN 0.8616
1213 ENL 0.8614
1214 8NX 0.8612
1215 BCF 0.8610
1216 RXA 0.8609
1217 13X 0.8608
1218 4RU 0.8608
1219 IBF 0.8606
1220 NVU 0.8604
1221 HCS 0.8602
1222 8EW 0.8602
1223 1SA 0.8600
1224 AX2 0.8598
1225 GOJ 0.8598
1226 MED 0.8598
1227 CIY 0.8597
1228 Z5P 0.8596
1229 NCD 0.8591
1230 2TQ 0.8590
1231 RUY 0.8589
1232 F4E 0.8588
1233 2LY 0.8588
1234 A2G 0.8588
1235 KG1 0.8587
1236 280 0.8584
1237 X0W 0.8581
1238 2CZ 0.8580
1239 QBM 0.8580
1240 GJP 0.8578
1241 QMP 0.8578
1242 TMT 0.8577
1243 WDL 0.8576
1244 M3H 0.8576
1245 ONR 0.8575
1246 NF3 0.8572
1247 TMZ 0.8570
1248 NAG 0.8570
1249 4XX 0.8568
1250 0FK 0.8559
1251 FK8 0.8559
1252 OXE 0.8553
1253 1DU 0.8552
1254 HAI 0.8552
1255 YQA 0.8551
1256 DPF 0.8550
1257 TBS 0.8550
1258 8XL 0.8550
1259 D3M 0.8543
1260 NGA 0.8542
1261 EXD 0.8540
1262 VAL 0.8533
1263 CLZ 0.8532
1264 4AV 0.8527
1265 IAC 0.8526
1266 ALE 0.8525
1267 MAJ 0.8519
1268 BBK 0.8511
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4UFH; Ligand: GIF; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4ufh.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback