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Receptor
PDB id Resolution Class Description Source Keywords
4U1H 1.59 Å NON-ENZYME: IMMUNE HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCA DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPE HOMO SAPIENS IMMUNOGLOBULIN HLA HIV IMMUNE SYSTEM
Ref.: A MOLECULAR SWITCH IN IMMUNODOMINANT HIV-1-SPECIFIC T-CELL EPITOPES SHAPES DIFFERENTIAL HLA-RESTRICTED RETROVIROLOGY V. 12 20 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:304;
A:301;
B:302;
A:303;
A:308;
A:307;
A:309;
A:302;
B:301;
A:305;
A:306;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
GOL C:101;
B:303;
A:310;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
THR PRO GLN ASP LEU ASN THR MET LEU C:1;
Valid;
Atoms found LESS than expected: % Diff = 0;
submit data
1031.18 n/a S(CCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5U98 2 Å NON-ENZYME: IMMUNE THE CRYSTAL STRUCTURE OF A SELF-PEPTIDE COMPLEXED TO ABACAVI B*57:01 HOMO SAPIENS MHC ANTIGEN PRESENTING CELL T-CELL RECEPTOR HUMAN LEUKOCYANTIGEN DRUG HYPERSENSITIVITY ABACAVIR HYPERSENSITIVITY REPERTOIRE-ALTERING SMALL MOLECULE IMMUNE RESPONSE IMMUNOLIKE BETA-SANDWICH IMMUNE SYSTEM
Ref.: STRUCTURAL ELEMENTS RECOGNIZED BY ABACAVIR-INDUCED INT J MOL SCI V. 18 2017
Members (109)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 208 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
70% Homology Family (360)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 62 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
110 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
111 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
112 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
113 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
114 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
115 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
116 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
117 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
118 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
119 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
120 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
121 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
122 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
123 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
124 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
125 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
126 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
127 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
128 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
129 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
130 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
132 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
133 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
134 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
135 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
136 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
137 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
138 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
139 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
140 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
141 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
142 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
143 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
144 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
145 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
146 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
147 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
148 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
149 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
150 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
151 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
152 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
153 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
154 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
155 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
156 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
157 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
158 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
159 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
160 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
161 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
162 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
163 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
164 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
165 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
166 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
167 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
168 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
169 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
170 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
171 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
172 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
173 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
174 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
175 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
176 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
177 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
178 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
179 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
180 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
181 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
182 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
183 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
184 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
185 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
186 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
187 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
188 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
189 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
190 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
191 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
192 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
193 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
194 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
195 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
196 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
197 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
198 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
199 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
200 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
201 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
202 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
203 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
204 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
205 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
206 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
207 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
208 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
209 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
210 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
211 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
212 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
213 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
214 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
215 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
216 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
217 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
218 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
219 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
220 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
221 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
222 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
223 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
224 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
225 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
226 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
227 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
228 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
229 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
230 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
231 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
232 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
233 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
234 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
235 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
236 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
237 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
238 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
239 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
240 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
241 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
242 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
243 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
244 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
245 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
246 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
247 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
248 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
249 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
251 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
252 1HSB - ALA VAL ALA n/a n/a
253 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
254 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
255 5GRG - SER SER CYS SER SER CYS n/a n/a
256 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
257 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
258 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
259 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
260 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
261 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
262 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
263 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
264 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
265 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
266 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
267 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
268 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
269 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
270 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
271 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
272 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
274 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
275 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
276 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
277 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
278 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
279 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
281 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
282 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
283 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
284 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
285 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
286 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
288 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
289 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
291 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
292 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
293 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
294 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
295 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
296 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
297 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
298 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
299 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
300 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
301 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
303 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
304 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
305 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
306 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
307 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
308 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
309 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
310 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
311 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
312 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
313 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
314 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
315 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
316 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
317 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
318 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
319 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
320 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
321 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
322 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
323 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
324 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
325 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
326 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
327 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
328 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
329 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
330 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
331 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
332 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
333 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
334 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
335 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
336 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
337 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
338 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
339 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
340 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
341 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
342 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
343 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
344 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
345 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
346 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
347 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
348 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
349 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
350 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
351 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
352 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
353 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
354 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
355 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
356 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
357 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
358 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
359 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
360 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
50% Homology Family (366)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 42 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
110 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
111 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
112 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
113 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
114 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
115 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
116 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
117 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
118 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
119 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
120 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
121 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
122 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
123 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
124 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
125 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
126 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
127 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
128 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
129 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
130 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
132 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
133 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
134 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
135 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
136 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
137 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
138 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
139 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
140 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
141 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
142 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
143 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
144 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
145 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
146 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
147 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
148 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
149 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
150 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
151 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
152 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
153 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
154 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
155 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
156 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
157 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
158 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
159 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
160 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
161 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
162 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
163 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
164 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
165 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
166 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
167 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
168 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
169 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
170 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
171 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
172 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
173 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
174 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
175 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
176 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
177 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
178 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
179 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
180 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
181 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
182 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
183 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
184 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
185 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
186 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
187 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
188 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
189 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
190 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
191 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
192 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
193 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
194 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
195 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
196 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
197 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
198 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
199 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
200 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
201 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
202 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
203 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
204 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
205 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
206 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
207 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
208 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
209 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
210 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
211 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
212 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
213 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
214 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
215 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
216 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
217 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
218 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
219 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
220 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
221 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
222 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
223 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
224 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
225 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
226 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
227 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
228 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
229 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
230 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
231 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
232 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
233 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
234 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
235 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
236 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
237 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
238 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
239 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
240 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
241 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
242 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
243 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
244 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
245 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
246 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
247 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
248 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
249 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
251 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
252 1HSB - ALA VAL ALA n/a n/a
253 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
254 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
255 5GRG - SER SER CYS SER SER CYS n/a n/a
256 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
257 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
258 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
259 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
260 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
261 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
262 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
263 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
264 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
265 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
266 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
267 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
268 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
269 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
270 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
271 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
272 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
274 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
275 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
276 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
277 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
278 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
279 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
281 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
282 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
283 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
284 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
285 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
286 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
288 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
289 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
291 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
292 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
293 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
294 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
295 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
296 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
297 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
298 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
299 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
300 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
301 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
303 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
304 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
305 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
306 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
307 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
308 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
309 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
310 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
311 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
312 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
313 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
314 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
315 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
316 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
317 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
318 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
319 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
320 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
321 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
322 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
323 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
324 4CVZ - TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU n/a n/a
325 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
326 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
327 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
328 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
329 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
330 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
331 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
332 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
333 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
334 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
335 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
336 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
337 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
338 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
339 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
340 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
341 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
342 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
343 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
344 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
345 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
346 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
347 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
348 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
349 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
350 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
351 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
352 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
353 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
354 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
355 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
356 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
357 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
358 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
359 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
360 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
361 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
362 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
363 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
364 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
365 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
366 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: THR PRO GLN ASP LEU ASN THR MET LEU; Similar ligands found: 109
No: Ligand ECFP6 Tc MDL keys Tc
1 THR PRO GLN ASP LEU ASN THR MET LEU 1 1
2 THR PRO TYR ASP ILE ASN GLN MET LEU 0.691176 0.926471
3 VAL PRO LEU THR GLU ASP ALA GLU LEU 0.614173 0.904762
4 ALA MET ALA PRO ARG THR LEU LEU LEU 0.58209 0.819444
5 ILE PRO LEU THR GLU GLU ALA GLU LEU 0.565891 0.861538
6 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.546763 0.816901
7 ACE PRO GLN GLN ALA THR ASP ASP 0.535433 0.890625
8 ASN LEU VAL PRO MET VAL ALA THR VAL 0.528986 0.984127
9 ASN LEU VAL PRO GLN VAL ALA THR VAL 0.525547 0.920635
10 LEU PRO PHE ASP LYS THR THR ILE MET 0.513158 0.897059
11 GLN MET PRO THR GLU ASP GLU TYR 0.510204 0.897059
12 LEU PRO PHE ASP LYS SER THR ILE MET 0.509554 0.884058
13 VAL MET ALA PRO ARG THR LEU PHE LEU 0.506494 0.797297
14 TYR MET PHE PRO ASN ALA PRO TYR LEU 0.503311 0.873239
15 ILE MET ASP GLN VAL PRO PHE SER VAL 0.496732 0.882353
16 ACE ALA PRO GLN VAL STA VAL MET HIS PRO 0.490323 0.926471
17 ALA SER ASN GLU ASP MET GLU THR MET 0.488 0.738462
18 LEU PRO PHE ASP ARG THR THR ILE MET 0.487342 0.824324
19 PHE PRO THR LYS ASP VAL ALA LEU 0.486667 0.850746
20 ASN LEU VAL PRO MET VAL ALA VAL VAL 0.485507 0.920635
21 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.482269 0.75
22 VAL PRO LEU ARG PRO MET THR TYR 0.480519 0.813333
23 PHE ASN PHE PRO GLN ILE THR 0.475524 0.838235
24 ASN LEU VAL PRO MET VAL ALA ALA VAL 0.47482 0.920635
25 SER MET PRO GLU LEU SER PRO VAL LEU 0.474453 0.924242
26 GLU ALA THR GLN LEU MET ASN 0.472868 0.730159
27 ARG PRO GLN VAL PRO LEU ARG PRO MET 0.469799 0.802817
28 SER ALA GLU PRO VAL PRO LEU GLN LEU 0.468085 0.863636
29 SER ASP PTR MET ASN MET THR PRO 0.466667 0.815789
30 LYS PRO SEP GLN GLU LEU 0.465649 0.75
31 PTR VAL PRO MET LEU 0.464286 0.77027
32 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.463415 0.794872
33 ILE THR ASP GLN VAL PRO PHE SER VAL 0.461039 0.838235
34 ACE MET GLN SER TPO PRO LEU NH2 0.457746 0.821918
35 ALA PRO SER PTR VAL ASN VAL GLN ASN 0.456954 0.753247
36 ALA SER ASN GLU ASN MET GLU THR MET 0.456 0.738462
37 SER PRO ILE VAL PRO SER PHE ASP MET 0.454545 0.884058
38 SER ARG ASP HIS SER ARG THR PRO MET 0.453988 0.837838
39 LYS LEU THR PRO LEU CYS VAL THR LEU 0.450704 0.876923
40 SER GLU CYS THR THR PRO CYS 0.447761 0.861538
41 ASN LEU VAL PRO SER VAL ALA THR VAL 0.446809 0.892308
42 ASP ARG VAL GLU LEU ASN ALA PRO ARG GLN 0.446667 0.75
43 LEU PRO PHE GLU LYS SER THR VAL MET 0.44375 0.897059
44 ALA PRO THR MET PRO PRO PRO LEU PRO PRO 0.441176 0.938462
45 ACE MET GLN SER SEP PRO LEU NH2 0.440559 0.808219
46 LEU PRO SER PHE GLU THR ALA LEU 0.44 0.850746
47 ASN LEU VAL PRO THR VAL ALA THR VAL 0.438849 0.920635
48 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.4375 0.72973
49 ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR 0.437086 0.811594
50 LYS VAL PRO ARG ASN GLN ASP TRP LEU 0.436782 0.736842
51 ASN LEU VAL PRO VAL VAL ALA THR VAL 0.435714 0.920635
52 ALA LEU LYS ILE ASP ASN MET ASP 0.434783 0.738462
53 SER LEU LEU MET TRP ILE THR GLN LEU 0.434211 0.746479
54 LYS PRO ILE VAL GLN TYR ASP ASN PHE 0.432927 0.805556
55 ARG PRO MET THR PHE LYS GLY ALA LEU 0.432749 0.810811
56 SER LEU LYS ILE ASP ASN MET ASP 0.432624 0.757576
57 SER ASP ILE LEU PHE PRO ALA ASP SER 0.432432 0.823529
58 LEU PRO PRO LEU ASP ILE THR PRO TYR 0.432258 0.826087
59 LEU PRO GLU THR GLY 0.429688 0.875
60 SER PRO HIS ASN PRO ILE SER ASP VAL ASP 0.42963 0.878788
61 MET CYS PRO ARG MET THR ALA VAL MET 0.429487 0.84507
62 ACE PRO ASP PTR GLU ASN LEU 0.427586 0.773333
63 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.426136 0.826667
64 THR PRO ARG VAL THR GLY GLY GLY ALA MET 0.425806 0.847222
65 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.423841 0.75
66 LEU PRO PHE GLU ARG ALA THR ILE MET 0.423529 0.810811
67 ACE PRO VAL GLN GLU THR NH2 0.423077 0.875
68 ARG PRO MET THR TYR LYS GLY ALA LEU 0.421965 0.802632
69 ALA PRO ASP THR ARG PRO 0.421429 0.777778
70 ALA SER ASN GLU ASN ALA GLU THR MET 0.421053 0.738462
71 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.420732 0.805556
72 LEU PRO PHE GLU ARG ALA THR VAL MET 0.420118 0.821918
73 SER ALA PRO ASP THR ARG PRO ALA 0.418919 0.767123
74 ACE ASP LEU GLN THR SER ILE 0.418605 0.626866
75 ASN ARG PRO ILE LEU SER LEU 0.417808 0.791667
76 SER PRO LEU ASP SER LEU TRP TRP ILE 0.417722 0.780822
77 LYS MET ASN THR GLN PHE THR ALA VAL 0.417219 0.761194
78 ARG GLN ALA SEP ILE GLU LEU PRO SER MET 0.417143 0.759494
79 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.416667 0.766234
80 MET GLN SER TPO PRO LEU 0.416107 0.833333
81 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.415584 0.8
82 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.415584 0.802817
83 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.414634 0.783784
84 ALA SER ASN GLU HIS MET GLU THR MET 0.413793 0.768116
85 SER LEU LEU MET TRP ILE THR GLN SER 0.412903 0.746479
86 GLU PTR LEU GLY LEU ASP VAL PRO VAL 0.412698 0.825397
87 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.4125 0.75
88 MET HIS PRO ALA GLN THR SER GLN TRP 0.411429 0.861111
89 ACE GLN LEU VAL THR SER LEU 0.41129 0.636364
90 FME TYR PHE ILE ASN ILE LEU THR LEU 0.410596 0.7
91 PHE GLN PRO GLN ASN GLY GLN PHE ILE 0.410256 0.757143
92 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.408284 0.74359
93 ILE SER PRO ARG THR LEU ASP ALA TRP 0.407821 0.74359
94 ILE SER TYR GLY ASN ASP ALA LEU MET PRO 0.407186 0.9
95 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.406977 0.794521
96 ASN SER THR LEU GLN 0.406504 0.646154
97 ALA THR LYS ILE ASP ASN LEU ASP 0.405797 0.723077
98 GLU THR LEU LEU ASP LEU ASP PHE ASP PRO 0.405594 0.892308
99 GLU THR LEU LEU ASP LEU ASP PHE LEU GLU 0.403226 0.666667
100 CYS THR GLU LEU LYS LEU ASN ASP TYR 0.402685 0.720588
101 ALA ASN SER ARG TRP GLN ASP THR ARG LEU 0.402439 0.662338
102 GLU GLY PRO ARG ASN GLN ASP TRP LEU 0.402299 0.736842
103 LYS MET ASP SEP PHE LEU ASP MET GLN LEU 0.401274 0.653333
104 GLU PRO GLN ALA PRO TRP MET GLU GLN 0.401235 0.8
105 GLU PRO GLN ALA PRO TRP MET GLU 0.401235 0.8
106 VAL SER GLN ASN TYR PRO ILE VAL GLN ASN 0.4 0.828571
107 LYS ALA PRO ARG ALY GLN LEU ALA THR LYS 0.4 0.694444
108 SER LEU ILE PRO TPO PRO ASP LYS 0.4 0.783784
109 PRO MET GLN SER TPO PRO LEU 0.4 0.835616
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5U98; Ligand: 1KX; Similar sites found with APoc: 185
This union binding pocket(no: 1) in the query (biounit: 5u98.bio2) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 4NS0 PIO None
2 1KGI T4A 2.3622
3 2GQS C2R 2.53165
4 3QRC SCR 2.54777
5 2Z77 HE7 2.8777
6 4D4U FUC GAL NAG 3.0303
7 4EKQ NPO 3.20856
8 2XG5 EC2 3.21101
9 2XG5 EC5 3.21101
10 4ZU4 4TG 3.37838
11 5UMY TNN 3.57143
12 4RYV ZEA 3.87097
13 1EC9 XYH 3.97112
14 3WG3 A2G GAL NAG FUC 4.0404
15 5UC4 83S 4.0404
16 4CJN QNZ 4.0404
17 4WVW SLT 4.16667
18 4XMF HSM 4.34783
19 1WW5 SGA BGC 4.375
20 1N5S ADL 4.46429
21 3ZXE PGZ 4.51128
22 5T7I LAT NAG GAL 4.51613
23 5GLT BGC GAL NAG GAL 5.05051
24 2Y24 XYP XYP GCV XYP 5.05051
25 3A16 PXO 5.05051
26 5U9J GER 5.05051
27 4KU7 PCG 5.05051
28 4IMO PWZ 5.11364
29 4ZSI GLP 5.26316
30 4OIT MAN 5.30973
31 6FOF LAT 5.61225
32 5NLD LBT 5.7554
33 2PFC PLM 6.01093
34 5TZO 7V7 6.06061
35 2WEI VGG 6.06061
36 6FXR AKG 6.06061
37 1Y7P RIP 6.06061
38 5L9V OGA 6.06061
39 1S5O 152 6.06061
40 1SDW IYT 6.06061
41 3A76 SPD 6.06061
42 5ZFJ 9BF 6.06061
43 3HQR OGA 6.06061
44 3NZ1 3NY 6.06061
45 5L9B AKG 6.06061
46 4X7Q 3YR 6.06061
47 1O9U ADZ 6.06061
48 5ZXD ATP 6.06061
49 1NVM OXL 6.06061
50 1QY1 PRZ 6.06061
51 4M8D 23J 6.06061
52 5NFB 8VT 6.25
53 4CLO XP0 6.4982
54 1NYW DAU 6.59898
55 1A78 TDG 6.71642
56 5B09 4MX 6.73077
57 3M3E GAL A2G NPO 6.8323
58 5DG2 GAL GLC 7.07071
59 2HRL SIA GAL SIA BGC NGA CEQ 7.07071
60 4WN5 MVC 7.07071
61 5LHT TIH 7.07071
62 5N0L ILE 7.07071
63 4Y8D 49J 7.07071
64 5E7G XYS BGC BGC XYS BGC XYS BGC BGC BGC 7.07071
65 3H7J PPY 7.07071
66 2VL1 GLY GLY 7.07071
67 5TVF CGQ 7.07071
68 1OPB RET 7.07071
69 4LCQ URQ 7.07071
70 3KYF 5GP 5GP 7.35931
71 1I7M PUT 7.46269
72 1I7M CG 7.46269
73 5MJA 7O3 7.58123
74 5C8W PCG 7.69231
75 4YLZ LAT NAG GAL 7.84314
76 3OCP CMP 7.91367
77 5X7Q GLC GLC GLC GLC GLC 7.94224
78 5X7Q GLC GLC GLC GLC 7.94224
79 4KBA 1QM 7.94224
80 4LIT AKG 8.08081
81 3JU6 ANP 8.08081
82 3H9A PPY 8.08081
83 3AVR OGA 8.08081
84 6HDT BTN 8.08081
85 5W10 CMP 8.08081
86 5INJ 6C7 8.08081
87 3WUD GLC GAL 8.08823
88 5HWV MBN 8.46154
89 3SXS PP2 9.09091
90 2Y6O 1N1 9.09091
91 4GQP B40 9.09091
92 3WBZ ATP 9.09091
93 6GQM F8H 9.09091
94 1U18 HSM 9.18919
95 3ZO7 K6H 9.57447
96 5XVG 8FX 9.74729
97 6F7X MFU 10
98 2HZQ STR 10.101
99 3GM5 CIT 10.101
100 3WUC GLC GAL 10.101
101 1OFL NGK GCD 10.101
102 5FYR INS 10.101
103 5ISY NAD 10.101
104 4PSR FUL 10.101
105 6E1Q CFA 10.101
106 5JWP AKG 10.101
107 2XUM OGA 10.101
108 6FA4 D1W 10.101
109 4H6B 10X 10.101
110 6GIN IR2 10.101
111 4BCS BTN 10.101
112 3P3N AKG 10.101
113 4CSD MFU 10.101
114 1SBR VIB 10.101
115 3FW3 ETS 10.1504
116 3RF4 FUN 10.3448
117 1TW4 CHD 10.4
118 4K55 H6P 10.4839
119 2BYC FMN 10.9489
120 5I0U DCY 11
121 5E5U 1PS 11.1111
122 3SAO NKN 11.1111
123 6D61 4AA 11.1111
124 1NKI PPF 11.1111
125 4Y24 TD2 11.1111
126 5HES 032 11.1111
127 1UMZ BGC BGC XYS BGC XYS GAL 11.1111
128 5H2U 1N1 11.1111
129 4HBM 0Y7 11.1111
130 1GZW GAL BGC 11.1111
131 2VN9 GVD 11.1111
132 6F6D AKG 11.1111
133 2CM4 RCL 11.3333
134 3ZGJ RMN 11.9134
135 1ULE GLA GAL NAG 12.1212
136 3GFZ FMN 12.1212
137 5V3D FCN 12.4138
138 6BU0 IHP 12.9771
139 5KJW 53C 12.9964
140 3NV3 GAL NAG MAN 13.0435
141 5MRH Q9Z 13.1313
142 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU 13.1579
143 1YRX FMN 13.2231
144 5FUI APY 13.6364
145 1IS3 LAT 14.1414
146 5F6U 5VK 14.1414
147 1GQG DCD 14.1414
148 1NSZ GLC 14.1414
149 3AJH BL3 14.1414
150 6GNO XDI 14.8148
151 4QYN RTL 15.0376
152 3VV1 GAL FUC 15.1515
153 4YZ5 SLT 15.1515
154 5UXM TRP 15.1515
155 5KWW 6YA 15.1515
156 2IYG FMN 15.3226
157 1KJ1 MAN 15.5963
158 1J3R 6PG 16.1616
159 3K4Z CBI 16.1616
160 4D1J DGJ 16.1616
161 4LAX FK5 16.1616
162 2ET1 GLV 16.1616
163 5YBN AKG 16.1616
164 4JH6 FCN 16.6667
165 2P7Q GG6 17.1717
166 2A1L PCW 17.1717
167 1H2M OGA 17.3077
168 2ZHL NAG GAL GAL NAG 18.1818
169 3WV6 GAL BGC 18.1818
170 5O9W AKG 18.1818
171 3V99 ACD 18.1818
172 2QL9 CIT 18.5567
173 1LNX URI 19.7531
174 1BHX ASP PHE GLU GLU ILE 20
175 3NX2 FER 20.202
176 3W6G FLC 20.202
177 5N2D 8J8 21.5278
178 1H2K OGA 21.9512
179 4QXB OGA 22.2222
180 3O2K DST 22.2222
181 1LSH PLD 23.2323
182 2H8H H8H 23.2323
183 2D6M LBT 23.2704
184 5NIU 8YZ 24.2188
185 5EZU MYR 25.8427
Pocket No.: 2; Query (leader) PDB : 5U98; Ligand: VAL THR THR ASP ILE GLN VAL LYS VAL; Similar sites found with APoc: 99
This union binding pocket(no: 2) in the query (biounit: 5u98.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 4V1F BQ1 None
2 3KPE TM3 None
3 5N8V KZZ None
4 4WG0 CHD None
5 2CB8 MYA None
6 3KO0 TFP None
7 4F4S EFO None
8 6BR8 6OU 1.5873
9 6BR8 PGV 1.5873
10 2VWA PTY 2.0202
11 1HBK MYR 2.24719
12 4DE3 DN8 2.28137
13 2GWH PCI 3.2491
14 3RV5 DXC 3.37079
15 1DTL BEP 3.72671
16 5IUY BOG 4.0404
17 1FX8 BOG 4.0404
18 3E70 GDP 4.0404
19 1GNI OLA 4.0404
20 5UC4 83S 4.0404
21 1YC4 43P 4.0404
22 1A05 IPM 4.0404
23 2DC1 CIT 4.66102
24 4RC8 STE 4.95496
25 2WOR 2AN 5
26 2RH1 CLR 5.05051
27 2PSJ CEI 5.05051
28 4V3I ASP LEU THR ARG PRO 5.05837
29 3KYQ DPV 6.06061
30 3F8C HT1 6.06061
31 5NM7 GLY 6.06061
32 1ZOY UQ1 6.06061
33 4NAT 2W5 6.06061
34 4RW3 TDA 6.13718
35 1M2Z BOG 7.00389
36 2HHP FLC 7.07071
37 1NF8 BOG 7.07071
38 2D5X L35 7.0922
39 4ZVV NAD 7.22022
40 4ZVV GN0 7.22022
41 3DZ6 PUT 7.46269
42 1I7M PUT 7.46269
43 6CB2 OLC 8.08081
44 1XX4 BAM 8.08081
45 3FAL REA 8.08081
46 2OZ5 7XY 8.08081
47 3W54 RNB 8.08081
48 5FPN KYD 8.30325
49 5N26 CPT 8.79121
50 2VKL MLT 8.88889
51 2BHW NEX 9.09091
52 3T3Z 9PL 9.09091
53 2BCG GER 9.2233
54 4G86 BNT 9.38628
55 3GF2 SAL 9.58904
56 3KP6 SAL 9.93377
57 5I8F ML1 10.101
58 6DIO CIT 10.101
59 2HZQ STR 10.101
60 4URN NOV 10.101
61 5V3Y 5V8 10.1083
62 5XJ7 87O 10.4478
63 3RLF MAL 10.8303
64 4MGA 27L 11.1111
65 5K53 STE 11.1111
66 4TV1 36M 11.1111
67 4MG7 27H 11.1111
68 6CHP F0Y 11.8012
69 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 12.1212
70 5C1M OLC 12.1212
71 2YVE MBT 12.1212
72 4ZGM 32M 12.2951
73 2PX6 DH9 12.6354
74 3SFI 3SF 13.1313
75 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 13.3333
76 1LTI GAL 13.5922
77 1LT3 GAL BGC 13.5922
78 1LTT GAL BGC 13.5922
79 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 14.1414
80 3WYJ H78 14.1414
81 4IBF 1D5 15.1515
82 3O01 DXC 15.1625
83 1TV5 N8E 16.1616
84 5ZCO PEK 16.1616
85 1I0B PEL 16.6065
86 3RGZ BLD 17.1717
87 5LX9 OLB 18.1818
88 5LWY OLB 18.1818
89 4DK7 0KS 18.1818
90 5V4R MGT 20.9877
91 1TO9 HMH 22.2222
92 2QCX PF1 22.2222
93 4OGQ 7PH 23.5294
94 4OGQ UMQ 23.5294
95 6GMN F4E 24.0385
96 5OCA 9QZ 28.2828
97 1GVE CIT 28.2828
98 1HK8 DGT 30.303
99 5VRH OLB 32.3232
Pocket No.: 3; Query (leader) PDB : 5U98; Ligand: 1KX; Similar sites found with APoc: 437
This union binding pocket(no: 3) in the query (biounit: 5u98.bio1) has 68 residues
No: Leader PDB Ligand Sequence Similarity
1 1NU4 MLA None
2 1UO5 PIH None
3 4F4S EFO None
4 4WG0 CHD None
5 5N8V KZZ None
6 3KO0 TFP None
7 1UO4 PIH None
8 6BR8 PGV 1.5873
9 4HK8 XYP XYP XYP XYP XYP XYP 1.5873
10 1PZL MYR 1.68776
11 4RT1 C2E 1.78571
12 4MZU TYD 1.80505
13 5HW4 SAM 2.01613
14 5OM2 DXT 2.0202
15 2VWA PTY 2.0202
16 5AWM ANP 2.16606
17 1HBK MYR 2.24719
18 4DE3 DN8 2.28137
19 4V2O CLQ 2.43902
20 1J6W MET 2.85714
21 3SRV S19 2.88809
22 4IEN GDP 3.0303
23 4D4U FUC GAL NDG FUC 3.0303
24 4D52 GXL 3.0303
25 4D52 GIV 3.0303
26 1F52 ADP 3.0303
27 5UC1 486 3.0303
28 1RZX ACE VAL LYS GLU SER LEU VAL 3.06122
29 3P7N FMN 3.10078
30 2GWH PCI 3.2491
31 3B6R ADP 3.2491
32 5U6C 7YS 3.2491
33 1R6N 434 3.31754
34 3RV5 DXC 3.37079
35 2ICK DMA 3.43348
36 2WCJ M21 3.5461
37 4NKW PLO 3.61011
38 2FP2 TSA 3.61446
39 1DTL BEP 3.72671
40 1DZK PRZ 3.82166
41 5H9Q TD2 3.87097
42 1F5F DHT 3.90244
43 4HWT 1B2 4.0404
44 3E70 GDP 4.0404
45 5IUY BOG 4.0404
46 5UNJ RJW 4.0404
47 3TY3 GGG 4.0404
48 1GNI OLA 4.0404
49 3AQT RCO 4.08163
50 1L6O SER LEU LYS LEU MET THR THR VAL 4.21053
51 1FK5 OLA 4.30108
52 1JGS SAL 4.34783
53 1UVC STE 4.3956
54 4U0W 16G 4.47154
55 5BVB DOG 4.54545
56 4INI AMP 4.61538
57 2QK4 ATP 4.69314
58 4RC8 STE 4.95496
59 2WOR 2AN 5
60 1FGX U5P 5.05051
61 5LUN OGA 5.05051
62 1SJD NPG 5.05051
63 3RGA LSB 5.05051
64 4DW4 U5P 5.05051
65 4RF7 ARG 5.05051
66 5K21 6QF 5.05051
67 4K79 GAL A2G 5.05051
68 4RHP PEF 5.05051
69 2RH1 CLR 5.05051
70 5EO8 TFU 5.05051
71 4O9S 2RY 5.05051
72 1H4H XYP XYS XYP 5.05051
73 4DXJ 0M9 5.05051
74 4DXJ IPE 5.05051
75 2OFV 242 5.05415
76 3GC8 B45 5.05415
77 4V3I ASP LEU THR ARG PRO 5.05837
78 2J5B TYE 5.41516
79 4FFG 0U8 5.41516
80 5VAD PRO 5.41516
81 1ZDQ MSM 5.77617
82 3WUR O4B 5.84795
83 3KYQ DPV 6.06061
84 5ACM MBT 6.06061
85 5OLK DTP 6.06061
86 4MOB ADP 6.06061
87 3F8C HT1 6.06061
88 6BR9 PGV 6.06061
89 1ZOY UQ1 6.06061
90 1UNB AKG 6.06061
91 4KRI 1SH 6.06061
92 5MBC FMN 6.06061
93 2VDF OCT 6.06061
94 3NJQ NJQ 6.06061
95 3SHR CMP 6.06061
96 1U3R 338 6.06061
97 1UNB PN1 6.06061
98 5LI9 ACP 6.06061
99 5NWI TYR PHE SER SEP ASN 6.06061
100 6D6L FY4 6.06061
101 1RL4 BL5 6.06061
102 3W68 VIV 6.06061
103 4DOO DAO 6.06061
104 3JUQ AJD 6.06061
105 4O1Z MXM 6.06061
106 1SO2 666 6.06061
107 3JUQ AKD 6.06061
108 3T1A 5MA 6.06061
109 6FQZ 6PG 6.06061
110 4RW3 TDA 6.13718
111 4EE7 PIS 6.13718
112 2NSX IFM 6.13718
113 1VRP ADP 6.13718
114 5FPX GLY SER SER HIS HIS HIS HIS HIS 6.19469
115 3B2Q ATP 6.4982
116 1XNK XS2 6.63265
117 1F9V