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Receptor
PDB id Resolution Class Description Source Keywords
4TMZ 2.28 Å NON-ENZYME: OTHER TRANSLATION INITIATION FACTOR EIF5B (517-858) FROM C. THERMO BOUND TO GTPGAMMAS AND POTASSIUM CHAETOMIUM THERMOPHILUM TRANSLATION TRANSLATION FACTOR GTPASE
Ref.: A MONOVALENT CATION ACTS AS STRUCTURAL AND CATALYTI COFACTOR IN TRANSLATIONAL GTPASES. EMBO J. V. 33 2547 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
K A:903;
B:903;
Part of Protein;
Part of Protein;
none;
none;
submit data
39.098 K [K+]
CL B:906;
B:905;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
MG A:902;
B:902;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
GOL B:904;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
GSP B:901;
A:901;
Valid;
Valid;
none;
none;
Kd = 0.92 uM
539.246 C10 H16 N5 O13 P3 S c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4TMZ 2.28 Å NON-ENZYME: OTHER TRANSLATION INITIATION FACTOR EIF5B (517-858) FROM C. THERMO BOUND TO GTPGAMMAS AND POTASSIUM CHAETOMIUM THERMOPHILUM TRANSLATION TRANSLATION FACTOR GTPASE
Ref.: A MONOVALENT CATION ACTS AS STRUCTURAL AND CATALYTI COFACTOR IN TRANSLATIONAL GTPASES. EMBO J. V. 33 2547 2014
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
3 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
4 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 139
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 9GM 0.770115 0.925
10 GMV 0.767442 0.925
11 G 0.756098 0.935897
12 5GP 0.756098 0.935897
13 G2R 0.747253 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GKE 0.744681 0.91358
17 GPG 0.73913 0.91358
18 GTG 0.736842 0.891566
19 G3A 0.729167 0.925
20 G5P 0.721649 0.925
21 GDR 0.71875 0.91358
22 GFB 0.71875 0.91358
23 GAV 0.714286 0.987179
24 GP2 0.712644 0.91358
25 6CK 0.71134 0.891566
26 Y9Z 0.708333 0.860465
27 JB2 0.69697 0.91358
28 GKD 0.69697 0.91358
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 YGP 0.663265 0.858824
35 JB3 0.657143 0.902439
36 GDP ALF 0.645833 0.847059
37 GDP AF3 0.645833 0.847059
38 ALF GDP 0.645833 0.847059
39 GMP 0.641975 0.835443
40 G3D 0.638298 0.935897
41 NGD 0.635514 0.91358
42 2MD 0.633027 0.894118
43 CAG 0.630631 0.840909
44 G4P 0.625 0.935897
45 FEG 0.62037 0.83908
46 U2G 0.62037 0.891566
47 G G 0.617647 0.901235
48 MGD 0.616071 0.894118
49 ZGP 0.614679 0.872093
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 GH3 0.581633 0.924051
55 PGD 0.581197 0.926829
56 MD1 0.581197 0.894118
57 2GP 0.577778 0.911392
58 GCP G 0.563107 0.875
59 DGT 0.561224 0.878049
60 DBG 0.558333 0.902439
61 G1G 0.550847 0.880952
62 AGS 0.547368 0.924051
63 SAP 0.547368 0.924051
64 FE9 0.546219 0.8
65 A G 0.543103 0.888889
66 G4M 0.539062 0.840909
67 U A G G 0.538462 0.888889
68 G A A A 0.529915 0.878049
69 MGP 0.525253 0.91358
70 GPX 0.524272 0.898734
71 BGO 0.521739 0.879518
72 DGI 0.520408 0.878049
73 6G0 0.52 0.91358
74 IDP 0.515464 0.923077
75 R7I 0.51 0.898734
76 R5I 0.51 0.898734
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 AKW 0.495726 0.915663
81 G U 0.491525 0.857143
82 GTA 0.486726 0.891566
83 P2G 0.484536 0.839506
84 GPC 0.483607 0.83908
85 G C 0.483333 0.857143
86 P1G 0.474747 0.829268
87 DG 0.474227 0.865854
88 DGP 0.474227 0.865854
89 BA3 0.46875 0.85
90 IMP 0.463918 0.910256
91 B4P 0.463918 0.85
92 AP5 0.463918 0.85
93 G2Q 0.462963 0.91358
94 G G G RPC 0.459016 0.833333
95 APC G U 0.456 0.843373
96 ATP 0.45 0.873418
97 HEJ 0.45 0.873418
98 G G G C 0.448819 0.869048
99 A2D 0.447917 0.85
100 5FA 0.445545 0.873418
101 AQP 0.445545 0.873418
102 A G C C 0.445312 0.86747
103 G7M 0.444444 0.901235
104 G U34 0.442623 0.847059
105 01G 0.442478 0.860465
106 ITT 0.44 0.825
107 SGP 0.44 0.876543
108 HFD 0.436893 0.831325
109 G C C C 0.431818 0.879518
110 AT4 0.43 0.911392
111 AN2 0.43 0.8625
112 DG DG 0.428571 0.825581
113 A4P 0.42623 0.829545
114 UCG 0.424242 0.86747
115 PCG 0.423077 0.886076
116 C2E 0.423077 0.875
117 35G 0.423077 0.886076
118 MGO 0.420561 0.823529
119 ADP 0.42 0.873418
120 ANP 0.419048 0.851852
121 5GP 5GP 0.419048 0.839506
122 ADQ 0.418182 0.829268
123 7DT 0.417476 0.860759
124 AR6 0.417476 0.85
125 APR 0.417476 0.85
126 PRT 0.417391 0.910256
127 C1Z 0.415929 0.935897
128 A G U 0.414286 0.847059
129 AD9 0.413462 0.851852
130 UP5 0.413223 0.831325
131 A22 0.412844 0.8625
132 25L 0.412281 0.8625
133 M33 0.411765 0.839506
134 JBT 0.410405 0.783505
135 ACP 0.407767 0.851852
136 6YZ 0.407407 0.851852
137 ACQ 0.40566 0.851852
138 A1R 0.405405 0.8
139 A G U U 0.4 0.847059
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4TMZ; Ligand: GSP; Similar sites found with APoc: 552
This union binding pocket(no: 1) in the query (biounit: 4tmz.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3P4X ADP 1.15942
2 5MZN ADP 1.44928
3 3FWY ADP 1.44928
4 1SFF IK2 1.44928
5 1G6O ADP 1.51515
6 3H86 AP5 1.5625
7 5L3W GDP 1.63399
8 1JI0 ATP 1.66667
9 3MD0 GDP 1.73913
10 4IDN GNP 1.73913
11 3ZFD ANP 1.73913
12 5LB3 ADP 1.73913
13 1V8K ANP 1.73913
14 1ION ADP 1.73913
15 1QHG ATP 1.73913
16 3VM7 GLC 1.73913
17 1GOJ ADP 1.73913
18 4LC1 GDP 1.78042
19 2OWZ CIT 1.80723
20 4ZNL BEF ADP 1.82482
21 2HCR AMP 1.84049
22 3NHB ADP 1.96078
23 1RJ9 GCP 1.97368
24 5L3V GDP 2.00669
25 5L3S GNP 2.01342
26 5L3S G 2.01342
27 2AWN ADP 2.02899
28 2RCN GDP 2.02899
29 2WOJ ADP ALF 2.02899
30 1YTM ATP 2.02899
31 3DZD ADP 2.02899
32 3QXC ATP 2.06612
33 2CJW GDP 2.08333
34 4NE2 SH2 2.09581
35 4NE2 ADP 2.09581
36 2IYL GDP 2.11268
37 4D81 ADP 2.12014
38 3DEF GDP 2.29008
39 2HT6 GDP 2.29885
40 1ZIN AP5 2.30415
41 4P4T GDP 2.31884
42 4H1V GNP 2.31884
43 2FSH ANP 2.31884
44 3QF7 ANP 2.31884
45 1G41 ADP 2.31884
46 5HR5 ADP 2.31884
47 1R6B ADP 2.31884
48 1ZUI SKM 2.38095
49 3E70 GDP 2.43902
50 1VKJ A3P 2.45614
51 5U32 GDP 2.54237
52 1OFH ADP 2.58065
53 1H65 GDP 2.59259
54 5ZXD ATP 2.6087
55 1OYY AGS 2.6087
56 2QG6 NMN 2.6087
57 2ZFI ADP 2.6087
58 3BFV ADP 2.6087
59 2Y65 ADP 2.6087
60 2J5V PCA 2.6087
61 1E2K TMC 2.6087
62 4FRZ ADP 2.6087
63 2ZR9 DTP 2.6087
64 5KGS 6SR 2.6087
65 5X40 ACP 2.73973
66 1UJ2 ADP 2.77778
67 1UJ2 C5P 2.77778
68 6AIC AMP 2.80374
69 1X6V ADP 2.85714
70 4GOX A3P 2.8754
71 2OFW ADX 2.88462
72 1TQ4 GDP 2.89855
73 1XP8 AGS 2.89855
74 1W0J ADP 2.89855
75 1W0J ADP BEF 2.89855
76 2PL3 ADP 2.9661
77 3B7G ANP 3.04348
78 1BG2 ADP 3.07692
79 3FJG 3PG 3.18725
80 1IWE IMP 3.18841
81 3TBK ANP 3.18841
82 5I34 GDP 3.18841
83 1FNN ADP 3.18841
84 4YS0 ADP 3.18841
85 4ZDJ UTP 3.18841
86 2VVG ADP 3.18841
87 4HSE ADP 3.18841
88 1Z6T ADP 3.18841
89 1VHT BA3 3.21101
90 4Q1A 2XZ 3.21429
91 4Q1A UDP 3.21429
92 1P72 ADP 3.29341
93 1MR3 G3D 3.31492
94 1RRC ADP 3.32226
95 2PEZ GGZ 3.35196
96 2PEZ DAT 3.35196
97 3ZQ6 ADP ALF 3.39506
98 4QOS ADP 3.39623
99 2RC8 DSN 3.40136
100 2V7Q ATP 3.42466
101 2CK3 ANP 3.42466
102 2CK3 ADP 3.42466
103 2V7Q ADP 3.42466
104 4RLQ 3SK 3.46821
105 1QF5 RPL 3.47826
106 1QF5 GDP 3.47826
107 2C9O ADP 3.47826
108 3ZH4 FLC 3.47826
109 2ZE7 DST 3.47826
110 2ZE7 AMP 3.47826
111 3DC4 ADP 3.48837
112 2XT3 ADP 3.48837
113 1LVG ADP 3.53535
114 3CX8 GSP 3.5503
115 4WOP CTP 3.55556
116 1SQ5 ADP 3.57143
117 3LN9 FLC 3.59712
118 1O3Y GTP 3.61446
119 3AB3 GDP 3.65854
120 4NU0 AP5 3.68664
121 3TMK T5A 3.7037
122 3FYH ADP 3.72671
123 1P4V GLY 3.72881
124 4PX9 ADP 3.76712
125 1SVK ALF GDP 3.76812
126 6AU6 GDP 3.76812
127 1F5N GNP 3.76812
128 6DEF GCP 3.76812
129 2CDN ADP 3.76812
130 1SVM ATP 3.76812
131 4IJ6 SEP 3.79147
132 4WZ6 ATP 3.7931
133 3QKT ANP 3.83481
134 5AHO TLA 3.86905
135 1G6H ADP 3.89105
136 2P3V SRT 3.90625
137 3KJI ADP 3.93701
138 1UKZ ADP 3.94089
139 1Y3A GDP 3.95137
140 2B8W ALF 5GP 3.96341
141 1FQK GDP 4
142 1FQK ALF 4
143 1NJF AGS 4
144 1NJF ADP 4
145 1OXV ANP 4.05797
146 3COB ADP 4.05797
147 2GKS ADP 4.05797
148 1NY5 ADP 4.05797
149 4UXH T5A 4.05797
150 1QF9 ALF 4.12371
151 1QF9 ADP 4.12371
152 1QF9 C5P 4.12371
153 1BH2 GSP 4.12698
154 1BO4 COA 4.16667
155 1NN5 ANP 4.18605
156 1NN5 2DT 4.18605
157 3Q72 GNP 4.21687
158 1L2T ATP 4.25532
159 2XTN GTP 4.2735
160 3R7F CP 4.27632
161 4QRH 0O2 4.28571
162 4B9E FAH 4.31894
163 1YZN GNP 4.32432
164 4R43 GDP 4.34783
165 4A4Z ANP 4.34783
166 3RC3 ANP 4.34783
167 2Q2Y ADP 4.34783
168 2Q2Y MKR 4.34783
169 5AK0 8V1 4.34783
170 2ZJ5 ADP 4.34783
171 1IN4 ADP 4.49102
172 4U5X GNP 4.49438
173 5XKT GNP 4.5
174 3TK1 GDP 4.54545
175 1YRB GDP 4.58015
176 3W9F I3P 4.61538
177 3FVQ ATP 4.63768
178 1T5C ADP 4.63768
179 1FEC FAD 4.63768
180 4AG5 ADP 4.63768
181 4QM7 GTP 4.67836
182 4BFW ZVW 4.71698
183 3RAB GNP 4.73373
184 1M7G ADX 4.73934
185 1M7G ADP 4.73934
186 1M7G AV2 4.73934
187 3QVV A3P 4.74576
188 5CK5 GDP 4.74684
189 2QQ0 ADP 4.8913
190 2QQ0 TMP 4.8913
191 2QQ0 ANP 4.8913
192 2QQ0 THM 4.8913
193 2NV2 GLN 4.90196
194 4ZG4 VO4 ADP 4.92754
195 5TSH ADP 4.92754
196 1W7J ADP BEF 4.92754
197 1P9B GDP 4.92754
198 2NCD ADP 4.92754
199 5TSH ANP 4.92754
200 4E3Q PMP 4.92754
201 4MKG AP5 5.06912
202 4MKF AP5 5.06912
203 1FP6 ADP 5.19031
204 4KBF AMP 5.21739
205 5BQ5 ADP BEF 5.29101
206 2CHG ANP 5.30973
207 3Q85 GNP 5.32544
208 4WZA ACP 5.43478
209 4WZA ADP 5.43478
210 5KSZ GCP 5.50725
211 4IHQ ADP 5.50725
212 6CS8 F9Y 5.50725
213 2FAH GDP 5.50725
214 1XKV ATP 5.50725
215 5N69 ADP 5.52764
216 1S3G AP5 5.52995
217 2G77 GDP 5.55556
218 2G77 AF3 5.55556
219 3FB4 AP5 5.55556
220 4LJ9 ACP 5.60472
221 4KFU ACP 5.66038
222 3B5J 12D 5.76132
223 6C90 ADP 5.76923
224 2XTZ GSP 5.7971
225 1IHU ADP 5.7971
226 1IHU AF3 5.7971
227 1Z06 GNP 5.82011
228 2IXE ATP 5.90406
229 1G3Q ADP 5.90717
230 2F9L GDP 6.03015
231 2VB6 ADP BEF 6.04027
232 5M04 GDP 6.08696
233 2DPY ADP 6.08696
234 2O0J ADP 6.08696
235 1QHH ATP 6.08696
236 2CE7 ADP 6.08696
237 4FCW ADP 6.10932
238 3DKP ADP 6.12245
239 1DS6 GDP 6.25
240 4YMU ATP 6.25
241 1OIX GDP 6.28272
242 1OIV GDP 6.28272
243 1YQT ADP 6.37681
244 1LVK MNT BEF 6.37681
245 3CV2 OXL 6.37681
246 1ZD9 GDP 6.38298
247 2D2F ADP 6.4
248 2GK6 ADP 6.41026
249 3BER AMP 6.4257
250 1KSH GDP 6.45161
251 3RWO GDP 6.48649
252 4L9Z OXL 6.48968
253 4V0K GDP 6.50888
254 4U00 ADP 6.55738
255 1D2N ANP 6.61765
256 5YV5 ADP 6.66667
257 4R2I ANP 6.66667
258 2BIF SIN 6.66667
259 2BIF ANP 6.66667
260 5KDO GDP 6.75676
261 1GOT GDP 6.84932
262 1B0U ATP 6.87023
263 4C4P GNP 6.93642
264 4OI4 ATP 6.95652
265 2HV8 GTP 6.97674
266 3UIE ANP 7
267 2KIN ADP 7
268 4X8O AP5 7.00935
269 4BAS GNP 7.03518
270 2HF9 GSP 7.07965
271 1TAD ALF 7.09877
272 1TAD GDP 7.09877
273 1Z83 AP5 7.14286
274 3VPB GLU 7.14286
275 2D7C GTP 7.18563
276 2GDJ ANP 7.19697
277 2OG2 MLI 7.24638
278 4IEE AGS 7.24638
279 4IOK XPO 7.24638
280 4IOK ADP 7.24638
281 4TL6 ANP 7.24638
282 1K6M AGS 7.24638
283 2ORV 4TA 7.26496
284 1AKY AP5 7.27273
285 2RGX AP5 7.28155
286 1G8S MET 7.3913
287 2BEK ATP 7.393
288 1APZ ASP 7.40741
289 3BOS CDP 7.43802
290 2FH5 GTP 7.47664
291 1ZJ6 G3D 7.48663
292 5BN3 ADP 7.53623
293 1GXU 2HP 7.69231
294 1FZQ GDP 7.73481
295 5H4S RAM 7.74648
296 1YZG GDP 7.82123
297 4PFO ADP 7.82609
298 3HU3 AGS 7.82609
299 1AQU A3P 7.82609
300 2GJ8 ALF GDP 8.13953
301 1PUJ GNP 8.15603
302 6G14 G4P 8.16327
303 1G16 GDP 8.23529
304 1U0J ADP 8.2397
305 1JJV ATP 8.25243
306 3B9Q MLI 8.27815
307 3ITJ CIT 8.28402
308 4XTR ATP 8.29493
309 4XVU ATP 8.29493
310 4XTR ADP 8.29493
311 5I0H ADP BEF 8.4058
312 2D7D ADP 8.4058
313 2XAU ADP 8.4058
314 1F9V ADP 8.4058
315 6CRK GDP 8.4507
316 1GP2 GDP 8.4507
317 5L3R GCP 8.53242
318 2QEN ADP 8.69565
319 3MWL 8OX 8.69565
320 3BC1 GNP 8.71795
321 1F2U ATP 8.72483
322 2QZ4 ADP 8.77863
323 4TTQ ATP 8.83721
324 2WKQ GTP 9.03614
325 4BQS K2Q 9.09091
326 4BQS ADP 9.09091
327 3W5J GDP 9.31373
328 4LPS GDP 9.50413
329 1R4A GNP 9.69697
330 1W4R TTP 9.74359
331 1GWN GTP 9.7561
332 4PJ3 ANP 9.85507
333 5KSP GDP 10
334 3IIJ ADP 10
335 3RLF ANP 10.1351
336 5GVR LMR 10.2564
337 1DAK ADP 10.2679
338 1DAK DPU 10.2679
339 2W58 ADP 10.396
340 3A1S GDP 10.4651
341 3T12 GDP ALF 10.6061
342 3T1O GDP 10.6061
343 2ODE ALF GDP 10.6383
344 1W5T ADP 10.7246
345 1W5T ANP 10.7246
346 5UIV ADP 10.7246
347 1M7B GTP 10.8696
348 2A5F GTP 10.8808
349 6C0B MLI 10.8974
350 1XX6 ADP 10.9948
351 2ZEJ GDP 11.413
352 3A4M ADP 11.5385
353 5DIF GNP 11.8143
354 5DHF GNP 11.8143
355 6CIT GNP 11.8143
356 5UWP GNP 11.8143
357 5UWQ GNP 11.8143
358 5UWJ GNP 11.8143
359 5UWU GNP 11.8143
360 5UWI GNP 11.8143
361 5UWR GNP 11.8143
362 5UWW GNP 11.8143
363 5UWH GNP 11.8143
364 5UWS GNP 11.8143
365 5DI9 GNP 11.8143
366 3REF GDP 11.8557
367 1XMV ADP 11.8841
368 6B4K ANP 11.8841
369 2IS6 ADP 11.8841
370 1KO8 6PG 12
371 2ZPA ADP 12.1739
372 5EXT ADP 12.3077
373 3GJ8 GDP 12.6697
374 3GJ4 GDP 12.6697
375 3GJ0 GDP 12.6697
376 3M1I GTP 12.7854
377 1YZQ GNP 12.9412
378 5BXQ GDP 12.963
379 4HAT GNP 12.963
380 1IBR GNP 12.963
381 3CH5 GDP 12.963
382 1G7C 5GP 13.0435
383 4HI0 GDP 13.0653
384 2QTV GNP 13.1737
385 3GJ7 GDP 13.2653
386 2FFQ GSP 13.4503
387 4CVN ADP 13.6126
388 5OCG GNP 13.7566
389 5UQW GDP 13.7566
390 5TAR GDP 14.0541
391 5TB5 GDP 14.0541
392 3H4S ADP 14.0741
393 2BCG GDP 14.0777
394 1F6B GDP 14.1414
395 4M9Q GNP 14.5374
396 1JJ7 ADP 14.6154
397 1NRJ GTP 14.6789
398 3GJ5 GDP 14.7059
399 1RYH GNP 14.7783
400 3VX3 ADP 14.9194
401 5UWO GNP 15
402 2C5L GTP 15.0289
403 1MKY GDP 15.0725
404 5ZBR ANP 15.2
405 4K81 GTP 15.2047
406 2BVN GNP 15.3623
407 1D8T GDP 15.3623
408 5O2T GSP 15.3846
409 2A9K GDP 15.508
410 5O74 GDP 15.5556
411 2J0V GDP 15.566
412 6D5E GNP 15.5689
413 6D5J GNP 15.5689
414 6D59 GNP 15.5689
415 6BVI GNP 15.5689
416 1LFD GNP 15.5689
417 6BVL GNP 15.5689
418 6D55 GNP 15.5689
419 6D56 GNP 15.5689
420 6BVJ GNP 15.5689
421 6D5G GNP 15.5689
422 6D5H GNP 15.5689
423 6BVK GNP 15.5689
424 6D5L GNP 15.5689
425 6BVM GNP 15.5689
426 6D5V GNP 15.5689
427 6D5M GNP 15.5689
428 6FA4 GNP 15.6069
429 4RD0 GDP 15.6522
430 3DDC GNP 15.6627
431 2UZI GTP 15.6627
432 1NVV GNP 15.6627
433 5WLB GNP 15.6627
434 1CLU DBG 15.6627
435 3KUD GDP 15.6627
436 1WQ1 GDP 15.6627
437 1WQ1 AF3 15.6627
438 3QBT GNP 15.7143
439 1WA5 GTP 15.9091
440 1D2E GDP 15.942
441 1GRN GDP 16.2304
442 4ITR GDP 16.2304
443 2NGR GDP 16.2304
444 1GRN AF3 16.2304
445 2NGR AF3 16.2304
446 1DAR GDP 16.2319
447 5KUT GDP 16.4021
448 1RE0 GDP 16.4634
449 1S9D GDP 16.4634
450 1ZC3 GNP 16.5714
451 5ZB0 ADP 16.6667
452 5ZB0 TYD 16.6667
453 2C78 GNP 16.8116
454 2C77 GNP 16.8116
455 1UPT GTP 16.9591
456 1U8Z GDP 17.2619
457 2YOH WMJ 17.619
458 1Z08 GNP 17.6471
459 4DCT GDP 17.6812
460 5Z69 AGS 17.6812
461 1Z2A GDP 17.8571
462 1M2O GNP 17.8947
463 1WF3 GNP 17.9402
464 1B7T ADP 17.9487
465 4HDO GNP 17.9641
466 1GUA GNP 17.9641
467 1KK1 GNP 17.971
468 3GJ3 GDP 18.1818
469 1KK8 BEF ADP 18.1818
470 5HCN GCP 18.3908
471 1SVI GDP 18.4615
472 1XEX ATP 18.6047
473 3PQC GDP 18.9744
474 1OS1 PYR 19.4203
475 1OS1 ATP 19.4203
476 1X1R GDP 19.6629
477 2A5J GDP 19.8953
478 1J2J GTP 20
479 3KTA AP5 20.3297
480 1CS4 GSP 20.4444
481 3IUY AMP 20.614
482 3ZIA ADP 20.6349
483 3ZIA ATP 20.6349
484 2GCO GNP 20.8955
485 2GCN GDP 20.8955
486 1S8F GDP 20.904
487 3ZS9 ADP ALF 21.0526
488 1R2Q GNP 21.1765
489 2WIC GNP 21.3483
490 3MJH GTP 21.4286
491 1KAO GDP 21.5569
492 1CR1 TTP 21.6216
493 5UWT GNP 21.7391
494 1E96 GTP 21.875
495 1I4D GDP 21.875
496 3EC1 GDP 22.029
497 4R98 GNH 22.5092
498 4D0N GDP 22.7027
499 1OW3 GDP 22.7979
500 3SBD GNP 22.9947
501 1MH1 GNP 23.1183
502 2W2X GSP 23.2432
503 1G4U GDP 23.3696
504 1G4U AF3 23.3696
505 5Y6N ADP 23.7681
506 1Z0F GDP 24.0223
507 2FJU GSP 24.1573
508 1HE1 GDP 24.4318
509 1HE1 AF3 24.4318
510 1CXZ GSP 24.7253
511 5IRC GDP 24.7312
512 5HPY GDP 24.8649
513 1KMQ GNP 25
514 2OM2 GDP 25
515 2WHX ADP 25.5072
516 2JLR ANP 25.5072
517 5XC5 GTP 25.5682
518 1TX4 ALF GDP 25.9887
519 3WXM GTP 26.3982
520 1Z0A GDP 26.4368
521 3T5G GDP 26.5193
522 6BSX E7S 26.9663
523 6BSX GDP 26.9663
524 1NF3 GNP 27.1795
525 1A4R GDP 27.2251
526 1A4R GNH 27.2251
527 5UPK GNP 27.5676
528 2QN6 GDP 27.7778
529 4NON GDP 28.8462
530 1Z0K GTP 29.0698
531 4DID GDP 29.5337
532 2BME GNP 29.5699
533 1DCP HBI 29.8077
534 1KY3 GDP 30.2198
535 1FQJ ALF 30.9524
536 1FQJ GDP 30.9524
537 1VG1 GDP 31.3514
538 1VG9 GDP 31.3514
539 1D5C GDP 31.4815
540 1TU3 GNP 31.6456
541 1EK0 GNP 31.7647
542 2WJG GDP 32.4468
543 1SKQ GDP 33.3333
544 1VG8 GNP 33.8164
545 1VG0 GDP 33.8164
546 2WJH GDP 36.1446
547 2WJH FLC 36.1446
548 1Z0J GTP 36.4706
549 1YVD GNP 37.2781
550 2HCJ GDP 37.8378
551 4B47 GDP 38.2609
552 5Z2M GTP 39.7727
Pocket No.: 2; Query (leader) PDB : 4TMZ; Ligand: GSP; Similar sites found with APoc: 10
This union binding pocket(no: 2) in the query (biounit: 4tmz.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3WWX DIA 1.15942
2 3ZZH ARG 1.9544
3 6BYF CIT 2.35294
4 4UOX PUT 2.6087
5 2X52 GYT 2.92398
6 4EZD SEY 3.76812
7 4JLS 3ZE 6.57895
8 2OAT PFM 7.53623
9 1T3D CYS 9.68858
10 1T36 ORN 11.8841
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