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Receptor
PDB id Resolution Class Description Source Keywords
4TL6 1.76 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF KAIC SYNECHOCOCCUS ELONGATUS (STRAIN PCC 79ORGANISM_TAXID: 1140 SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: CIRCADIAN RHYTHMS. ATOMIC-SCALE ORIGINS OF SLOWNESS CYANOBACTERIAL CIRCADIAN CLOCK. SCIENCE V. 349 312 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG B:302;
C:302;
A:302;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP C:301;
A:301;
B:301;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
CL C:303;
A:303;
B:303;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
35.453 Cl [Cl-]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4TL6 1.76 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF KAIC SYNECHOCOCCUS ELONGATUS (STRAIN PCC 79ORGANISM_TAXID: 1140 SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: CIRCADIAN RHYTHMS. ATOMIC-SCALE ORIGINS OF SLOWNESS CYANOBACTERIAL CIRCADIAN CLOCK. SCIENCE V. 349 312 2015
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 4TLA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4TL7 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 4TL8 - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
4 4TLC - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 4TL9 - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
6 4TLB - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
7 4TLE - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
8 4TL6 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 4TLD - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 4TLA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4TL7 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 4TL8 - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
4 4TLC - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 4TL9 - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
6 4TLB - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
7 4TLE - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
8 4TL6 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 4TLD - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 4TLA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4TL7 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 4TL8 - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
4 4TLC - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
5 4TL9 - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
6 4TLB - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
7 4TLE - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
8 4TL6 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 4TLD - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4TL6; Ligand: ANP; Similar sites found with APoc: 670
This union binding pocket(no: 1) in the query (biounit: 4tl6.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2WIC GNP None
2 4R98 GNH None
3 1S3G AP5 None
4 1GG6 APL None
5 5FUI APY None
6 3BOS CDP None
7 1Z08 GNP 1.17647
8 5IRR GSP 1.18577
9 2CHG ANP 1.32743
10 4JLV ADP 1.58103
11 1AQU A3P 1.58103
12 2BEK ATP 1.58103
13 1T8U A3P 1.58103
14 4LPS GDP 1.65289
15 1NRJ GTP 1.89873
16 4WEI GLC GAL 1.97628
17 1Q19 SSC 1.97628
18 4RZ3 ADP 1.97628
19 5IRN ADP 1.97628
20 1C3Q TZE 1.97628
21 6B8B ADP 2.00803
22 2F9L GDP 2.01005
23 3PQC GDP 2.05128
24 1QF9 ADP 2.06186
25 1QF9 C5P 2.06186
26 1QF9 ALF 2.06186
27 4BFW ZVW 2.20126
28 1AKY AP5 2.27273
29 1T5C ADP 2.29226
30 4C4P GNP 2.31214
31 5M04 GDP 2.37154
32 5LB3 ADP 2.37154
33 4ZNL BEF ADP 2.37154
34 2GWH A3P 2.37154
35 5AK0 8V1 2.37154
36 1ZCB GDP 2.37154
37 1TAD ALF 2.37154
38 1TAD GDP 2.37154
39 5MEX PAP 2.37154
40 2D2F ADP 2.4
41 3BC1 GNP 2.5641
42 3COB ADP 2.7668
43 1R0X ATP 2.7668
44 5W7Q GDP 2.7668
45 5W76 GDP 2.7668
46 5W75 GDP 2.7668
47 1H65 GDP 2.7668
48 5H68 AGS 2.7668
49 3KJI ADP 2.7668
50 1NST A3P 2.7668
51 5W75 SUC 2.7668
52 3FKQ ATP 2.7668
53 6DEF GCP 2.7668
54 2B6N ALA PRO THR 2.7668
55 2J5V PCA 2.7668
56 3HQP FDP 2.7668
57 2XTZ GSP 2.7668
58 1R6B ADP 2.7668
59 1QHG ATP 2.7668
60 1RRC ADP 2.7668
61 1AJ8 COA 2.7668
62 1G3M A3P 2.7668
63 1G3M PCQ 2.7668
64 3AB3 GDP 2.84553
65 4E03 ADP 2.91262
66 2CBZ ATP 2.95359
67 1YVD GNP 2.95858
68 1SVI GDP 3.07692
69 5ZXD ATP 3.16206
70 5Y6N ADP 3.16206
71 4IEE AGS 3.16206
72 1D2E GDP 3.16206
73 1XKV ATP 3.16206
74 3QKT ANP 3.16206
75 2ZPA ADP 3.16206
76 1W5T ANP 3.16206
77 1K6M AGS 3.16206
78 4A4Z ANP 3.16206
79 4H1V GNP 3.16206
80 1OS1 PYR 3.16206
81 4GOX A3P 3.16206
82 3KC1 2T6 3.16206
83 1OS1 ATP 3.16206
84 2Q8M AMP 3.16206
85 1W5T ADP 3.16206
86 1F9V ADP 3.16206
87 4X8O AP5 3.27103
88 3ZQ6 ADP ALF 3.39506
89 3GUZ PAF 3.40909
90 2EW1 GNP 3.48259
91 4BAS GNP 3.51759
92 5CK5 GDP 3.55731
93 1KK1 GNP 3.55731
94 3WY9 GDP 3.55731
95 3WYA GDP 3.55731
96 4R43 GDP 3.55731
97 1I7M CG 3.55731
98 4OHY ANP 3.55731
99 3DC4 ADP 3.55731
100 4OI4 ATP 3.55731
101 5NM7 GLY 3.55731
102 4FRZ ADP 3.55731
103 4XFR CIT 3.55731
104 1J2J GTP 3.61446
105 1O3Y GTP 3.61446
106 1XX6 ADP 3.66492
107 3N5C GDP 3.7037
108 3PCR GTP 3.7037
109 5TZO 7V7 3.7234
110 5H67 ATP 3.7234
111 3RWO GDP 3.78378
112 4QRH 0O2 3.80952
113 2XTN GTP 3.84615
114 1MR3 G3D 3.8674
115 2JAQ DCP 3.90244
116 4JLS 3ZE 3.94737
117 1BG2 ADP 3.95257
118 2GKS ADP 3.95257
119 2OG2 MLI 3.95257
120 2DPY ADP 3.95257
121 2QN6 GDP 3.95257
122 2ZFI ADP 3.95257
123 1MKY GDP 3.95257
124 3B9Q MLI 3.95257
125 4DCT GDP 3.95257
126 5MZN ADP 3.95257
127 5I0H ADP BEF 3.95257
128 1OFH ADP 3.95257
129 4RD0 GDP 3.95257
130 4P4T GDP 3.95257
131 5L3R GCP 3.95257
132 1G41 ADP 3.95257
133 5K5Z ANP 3.95257
134 1TQ4 GDP 3.95257
135 6AU6 GDP 3.95257
136 2OZE AGS 3.95257
137 1CS4 GSP 3.95257
138 1D2N ANP 3.95257
139 4GBM A3P 3.95257
140 1GOT GDP 3.95257
141 3VX3 ADP 4.03226
142 4YLG GDP 4.04624
143 3GJ0 GDP 4.0724
144 3GJ4 GDP 4.0724
145 3GJ3 GDP 4.0724
146 3GJ5 GDP 4.0724
147 3GJ8 GDP 4.0724
148 3GJ7 GDP 4.08163
149 4U00 ADP 4.09836
150 2ZX2 RAM 4.10256
151 1ION ADP 4.11523
152 5BXQ GDP 4.16667
153 1Z2A GDP 4.16667
154 3FB4 AP5 4.16667
155 4YMU ATP 4.16667
156 4TTQ ATP 4.18605
157 1G3Q ADP 4.21941
158 2PL3 ADP 4.23729
159 1L2T ATP 4.25532
160 2WHX ADP 4.34783
161 1YRB GDP 4.34783
162 5FTB ANP 4.34783
163 3AQ4 GDP 4.34783
164 4XGU ADP 4.34783
165 5FHD ADP ALF 4.34783
166 3QVV A3P 4.34783
167 5M7P ADP 4.34783
168 1F5N GNP 4.34783
169 4WZ6 ATP 4.34783
170 4I9B NAD 4.34783
171 3QVV 3QV 4.34783
172 4P83 U5P 4.3956
173 2HF9 GSP 4.42478
174 1RYH GNP 4.4335
175 2QG6 NMN 4.52261
176 1F6B GDP 4.54545
177 3TMK T5A 4.62963
178 1I4D GDP 4.6875
179 1DS6 GDP 4.6875
180 3RAB GNP 4.73373
181 1Z6T ADP 4.73773
182 1M7G AV2 4.73934
183 1M7G ADX 4.73934
184 1M7G ADP 4.73934
185 4AG5 ADP 4.74308
186 5BN3 ADP 4.74308
187 4B47 GDP 4.74308
188 1FNN ADP 4.74308
189 4FCW ADP 4.74308
190 4LJ9 ACP 4.74308
191 5KSZ GCP 4.74308
192 4ZG4 VO4 ADP 4.74308
193 1LVK MNT BEF 4.74308
194 4ZKD GDP 4.74308
195 5N69 ADP 4.74308
196 2JLR ANP 4.74308
197 1J78 OLA 4.74308
198 2QZ4 ADP 4.74308
199 2QEN ADP 4.74308
200 4Q1A 2XZ 4.74308
201 4Q1A UDP 4.74308
202 2AWN ADP 4.74308
203 1M2O GNP 4.74308
204 5KUT GDP 4.7619
205 2BCG GDP 4.85437
206 2FH5 GTP 4.86486
207 1YZN GNP 4.86486
208 4WOP CTP 4.88889
209 1DAK ADP 4.91071
210 1DAK DPU 4.91071
211 1D5C GDP 4.93827
212 5XKT GNP 5
213 4HI0 GDP 5.02513
214 1LVG ADP 5.05051
215 4IHQ ADP 5.13834
216 5IFS ADP 5.13834
217 4NON GDP 5.13834
218 3EZ2 ADP 5.13834
219 4D81 ADP 5.13834
220 6B4K ANP 5.13834
221 2FSH ANP 5.13834
222 1G7S GDP 5.13834
223 4V03 ADP 5.13834
224 3RLF ANP 5.13834
225 2VB6 ADP BEF 5.13834
226 2FAH GDP 5.13834
227 4PFO ADP 5.13834
228 2FJU GSP 5.13834
229 5JCZ GDP 5.13834
230 3ITJ CIT 5.13834
231 3HU3 AGS 5.13834
232 1WDT GTP 5.13834
233 1YTM ATP 5.13834
234 2AF6 FAD 5.13834
235 3NHB ADP 5.13834
236 4ZDJ UTP 5.13834
237 5HCN GCP 5.13834
238 6AIC AMP 5.14019
239 1KO8 6PG 5.14286
240 1HE1 GDP 5.18518
241 2FFQ GSP 5.26316
242 4K7O EKZ 5.35714
243 1ZUI SKM 5.35714
244 1F2U ATP 5.40541
245 1S9D GDP 5.41872
246 2KIN ADP 5.46218
247 4Z7X 3CX 5.46218
248 1KY3 GDP 5.49451
249 4MKG AP5 5.52995
250 3LRE ADP 5.5336
251 1OXV ANP 5.5336
252 3BFV ADP 5.5336
253 2OBM ADP 5.5336
254 4KBF AMP 5.5336
255 3A1S GDP 5.5336
256 2C9O ADP 5.5336
257 3DEF GDP 5.5336
258 2X7I CIT 5.5336
259 4NE2 SH2 5.5336
260 4NE2 ADP 5.5336
261 5VGR GDP 5.5336
262 2IS6 ADP 5.5336
263 3KLL MAL 5.5336
264 3IIJ ADP 5.55556
265 3WXM GTP 5.59284
266 3BY8 MLT 5.6338
267 4KFU ACP 5.66038
268 4R2I ANP 5.71429
269 2A5J GDP 5.75916
270 2IL4 COA 5.82524
271 4GOJ GNP 5.83333
272 3NCQ ATP 5.88235
273 2XT3 ADP 5.92885
274 1WF3 GNP 5.92885
275 5J1J ANP 5.92885
276 2C77 GNP 5.92885
277 1B0U ATP 5.92885
278 2C78 GNP 5.92885
279 1XP8 AGS 5.92885
280 2BIF SIN 5.92885
281 2BIF ANP 5.92885
282 5L3V GDP 5.92885
283 2QQ0 ADP 5.97826
284 2QQ0 TMP 5.97826
285 5OEC GDP 6.01093
286 3Q72 GNP 6.0241
287 5ZB0 ADP 6.06061
288 5ZB0 TYD 6.06061
289 1FZQ GDP 6.07735
290 3DKP ADP 6.12245
291 1X1R GDP 6.17978
292 2A5F GTP 6.21762
293 2GNK ATP 6.25
294 5KSP GDP 6.31579
295 1Z0A GDP 6.32184
296 4LHW GNP 6.32184
297 3TNF GNP 6.32184
298 3IO3 ADP 6.32184
299 4PPF FLC 6.32411
300 2ZR9 DTP 6.32411
301 3P4X ADP 6.32411
302 4J0Q GDP 6.32411
303 4PX9 ADP 6.32411
304 2IYL GDP 6.32411
305 1FP6 ADP 6.32411
306 5VHC BEF ADP 6.32411
307 4WZA ACP 6.32411
308 4WZA ADP 6.32411
309 1RJ9 GCP 6.32411
310 4DDY DN6 6.32411
311 3MGB PAP 6.32411
312 3Q9L ATP 6.32411
313 1XPJ TLA 6.34921
314 6BJO DUY 6.4
315 3SBD GNP 6.41711
316 4HAT GNP 6.42857
317 2BME GNP 6.45161
318 4MKF AP5 6.45161
319 1G16 GDP 6.47059
320 2J59 GTP 6.54762
321 2PZE ATP 6.55022
322 3IUY AMP 6.57895
323 3TKL GTP 6.63265
324 2O66 FLC 6.66667
325 5L3W GDP 6.71937
326 5L3S GNP 6.71937
327 4QOS ADP 6.71937
328 5DI3 GNP 6.71937
329 5L3S G 6.71937
330 1JJ7 ADP 6.71937
331 3CPJ GDP 6.72646
332 2CJW GDP 6.77083
333 3BER AMP 6.82731
334 1SQL GUN 6.84932
335 4NU0 AP5 6.91244
336 4DKX GDP 6.94444
337 1CXZ GSP 6.97674
338 3B5J 12D 6.99588
339 3UIE ANP 7
340 1Y63 ADP 7.06522
341 3Q85 GNP 7.10059
342 1PUJ GNP 7.11462
343 1IHU AF3 7.11462
344 5J1S ATP 7.11462
345 1IHU ADP 7.11462
346 5XDR ADP 7.11462
347 4LX0 BEF GDP 7.11462
348 3ZFD ANP 7.11462
349 5H4S RAM 7.11462
350 4KVA GTP 7.11462
351 4NCN GTP 7.11462
352 5WC2 ADP 7.11462
353 3SFV GDP 7.18232
354 4TMZ GSP 7.24638
355 1G8S MET 7.3913
356 2W58 ADP 7.42574
357 3NKV GNP 7.42857
358 1ZD9 GDP 7.44681
359 4KAX GTP 7.45342
360 2HT6 GDP 7.47126
361 4M9Q GNP 7.48899
362 1GOJ ADP 7.50988
363 6A20 ADP 7.50988
364 5ZBR ANP 7.50988
365 2B8W ALF 5GP 7.50988
366 3GJX GTP 7.50988
367 4IDN GNP 7.50988
368 2WKQ GTP 7.53012
369 5G41 AP5 7.62332
370 3CH5 GDP 7.69231
371 1V8K ANP 7.90514
372 4LC1 GDP 7.90514
373 5LTJ BEF 7.90514
374 2FNA ADP 7.90514
375 2D7D ADP 7.90514
376 5LTJ ADP 7.90514
377 2VWT PYR 7.90514
378 1GQY ACP 7.90514
379 5GOE GDP 7.90514
380 3QDK QDK 7.90514
381 3E70 GDP 7.92683
382 5BQ5 ADP BEF 7.93651
383 1UJ2 ADP 7.93651
384 1UJ2 C5P 7.93651
385 3FWY ADP 7.96178
386 1TU3 GNP 8.18713
387 3HCH RSM 8.21918
388 1R2Q GNP 8.23529
389 1JJV ATP 8.25243
390 1VHT BA3 8.25688
391 3TK1 GDP 8.3004
392 1U0J ADP 8.3004
393 1VKJ A3P 8.3004
394 1WA5 GTP 8.3004
395 2XAU ADP 8.3004
396 1SQ5 ADP 8.3004
397 2RCN GDP 8.3004
398 1G6H ADP 8.3004
399 1JI0 ATP 8.33333
400 1B7T ADP 8.33333
401 3MJH GTP 8.33333
402 2Y8E GNP 8.37989
403 1KK8 BEF ADP 8.44156
404 2CDN ADP 8.45771
405 1RE0 GDP 8.59729
406 5TSH ADP 8.69565
407 5TSH ANP 8.69565
408 3MD0 GDP 8.69565
409 1OYY AGS 8.69565
410 3T34 GDP 8.69565
411 1GXU 2HP 8.79121
412 1YZQ GNP 8.82353
413 1BO4 COA 8.92857
414 2VVG ADP 9.09091
415 3CNL GNP 9.09091
416 2CK3 ANP 9.09091
417 1W0J ADP 9.09091
418 1W0J ADP BEF 9.09091
419 2CK3 ADP 9.09091
420 5H7K GDP 9.09091
421 5H7J GCP 9.09091
422 1G4U GDP 9.09091
423 2V7Q ATP 9.09091
424 2V7Q ADP 9.09091
425 3B7G ANP 9.13043
426 5WDR GNP 9.35672
427 2GK6 ADP 9.48617
428 4YS0 ADP 9.48617
429 1Z0F GDP 9.49721
430 1G7C 5GP 9.57447
431 3T1O GDP 9.59596
432 3T12 GDP ALF 9.59596
433 1VG0 GDP 9.66184
434 1VG8 GNP 9.66184
435 2W2X GSP 9.67742
436 1GWN GTP 9.7561
437 3TBK ANP 9.88142
438 3BFX A3P 9.88142
439 1W7J ADP BEF 9.88142
440 5WP5 SAH 9.88142
441 1SVM ATP 9.88142
442 3T5G GDP 9.94475
443 1OIX GDP 9.94764
444 1OIV GDP 9.94764
445 6BSX GDP 10.1124
446 6BSX E7S 10.1124
447 5U32 GDP 10.1695
448 1S8F GDP 10.1695
449 3U6B GDP 10.2767
450 4P3Y GDP 10.2767
451 5YT0 GDP 10.2767
452 1SKQ GDP 10.2767
453 5FG3 GDP 10.2767
454 5JBQ GDP 10.2767
455 1D8T GDP 10.2767
456 4G5G GDP 10.2767
457 3U6K GDP 10.2767
458 2BVN GNP 10.2767
459 4PC3 GDP 10.2767
460 4XTR ATP 10.2767
461 2WOJ ADP ALF 10.2767
462 4XVU ATP 10.2767
463 4XTR ADP 10.2767
464 2Q2Y ADP 10.2767
465 2Q2Y MKR 10.2767
466 3EC1 GDP 10.6719
467 4KVG GTP 10.7143
468 1KSH GDP 10.7527
469 1HTW ADP 10.7595
470 1KAO GDP 10.7784
471 4HDO GNP 10.7784
472 4HDQ GNP 10.7784
473 3X1Z GNP 10.7784
474 1VG1 GDP 10.8108
475 1VG9 GDP 10.8108
476 1M7B GTP 10.8696
477 1FQK GDP 10.8844
478 2C5L GTP 10.9827
479 5UIV ADP 11.0132
480 2GJ8 ALF GDP 11.0465
481 4LYA ATP 11.0672
482 4YJ1 ADP 11.0672
483 3FVQ ATP 11.0672
484 3BD9 A3P 11.0672
485 4TQK NAG 11.0672
486 5F1V 3VN 11.0672
487 5SZH GNP 11.1111
488 1NF3 GNP 11.2821
489 1U8Z GDP 11.3095
490 3REF GDP 11.3402
491 5Z2M GTP 11.3636
492 4DID GDP 11.399
493 2CE7 ADP 11.4625
494 3RC3 ANP 11.4625
495 2Z5F A3P 11.4625
496 5UWQ GNP 11.4625
497 5UWO GNP 11.4625
498 5UWT GNP 11.4625
499 5UWS GNP 11.4625
500 3M1I GTP 11.4625
501 5DIF GNP 11.4625
502 5UWP GNP 11.4625
503 5UWI GNP 11.4625
504 5DHF GNP 11.4625
505 5UWR GNP 11.4625
506 5UWH GNP 11.4625
507 6CIT GNP 11.4625
508 5UWW GNP 11.4625
509 5UWU GNP 11.4625
510 3WYG GTP 11.4625
511 5UWJ GNP 11.4625
512 5DI9 GNP 11.4625
513 2NGR GDP 11.5183
514 1GRN GDP 11.5183
515 1A4R GNH 11.5183
516 4ITR GDP 11.5183
517 1A4R GDP 11.5183
518 6C90 ADP 11.5385
519 2WMO GTP 11.5789
520 2EFE GNH 11.6022
521 2G77 GDP 11.6162
522 2RGX AP5 11.6505
523 2W83 GTP 11.6883
524 1ZJ6 G3D 11.7647
525 5JCP GDP ALF 11.8577
526 5LEF GTP 12.1212
527 4YC7 GNP 12.1547
528 1QHH ATP 12.1739
529 2QTV GNP 12.2449
530 1XMV ADP 12.253
531 1DAR GDP 12.253
532 2IXE ATP 12.253
533 6G14 G4P 12.253
534 2A9K GDP 12.2995
535 2HV8 GTP 12.5
536 4D0G GTP 12.5714
537 1UAD GNP 12.5714
538 1ZC3 GNP 12.5714
539 1G6O ADP 12.6482
540 4KCT PYR 12.6482
541 5HR5 ADP 12.6482
542 1YZG GDP 12.8492
543 1EK0 GNP 12.9412
544 1YQT ADP 13.0435
545 5YV5 ADP 13.0435
546 1Z06 GNP 13.2275
547 1R4A GNP 13.3333
548 5EE5 GTP 13.4503
549 1UPT GTP 13.4503
550 1Z0J GTP 13.5593
551 3QBT GNP 13.5714
552 1V3S ATP 13.7931
553 5IRC GDP 13.9785
554 5HPY GDP 14.0541
555 1IN4 ADP 14.2292
556 1CR1 TTP 14.2292
557 6FA4 GNP 14.4509
558 5E5U MLI 14.5729
559 3DOE GTP 14.5833
560 6BCB GSP 14.5946
561 6BCA GSP 14.5946
562 6BC0 GSP 14.5946
563 1NY5 ADP 14.6245
564 1ZIN AP5 14.7465
565 4V0K GDP 14.7929
566 2X77 GDP 14.8148
567 4XOI GTP 15
568 2NCD ADP 15.0198
569 4ZI2 GNP 15.0376
570 1MH1 GNP 15.0538
571 3LXR GDP 15.1351
572 1Z83 AP5 15.3061
573 2GCO GNP 15.4229
574 2GCN GDP 15.4229
575 2WJG GDP 15.4255
576 5MVR ADP 15.4321
577 1OW3 GDP 15.544
578 1KMQ GNP 15.7609
579 1E96 GTP 15.7635
580 1BH2 GSP 15.8103
581 1Y3A GDP 15.8103
582 2OM2 GDP 15.8103
583 5WRI A3P 16.2055
584 5WRJ A3P 16.2055
585 5GVR LMR 16.6667
586 1FQJ GDP 16.6667
587 4D0N GDP 16.7568
588 1TX4 ALF GDP 16.9492
589 5XC5 GTP 17.0455
590 3W5J GDP 17.1569
591 3CX8 GSP 17.2414
592 2WJH GDP 17.4699
593 2WJH FLC 17.4699
594 4BQS K2Q 17.6136
595 4BQS ADP 17.6136
596 2J9D ADP 17.6471
597 6FAA ADP 18.1818
598 2OFW ADX 18.2692
599 4YDS ATP 18.4211
600 3DZD ADP 18.5771
601 2D7C GTP 19.0476
602 5EXT ADP 19.7628
603 4QM7 GTP 19.883
604 2Y65 ADP 20
605 4XSH GSP 20.0913
606 2J0V GDP 20.283
607 5G3Y ADP 20.354
608 1NJF ADP 20.4
609 1NJF AGS 20.4
610 4PJ3 ANP 20.5534
611 3ZIA ADP 20.6349
612 3ZIA ATP 20.6349
613 2ODE ALF GDP 20.9486
614 1SVK ALF GDP 20.9486
615 4HSE ADP 20.9486
616 6CRK GDP 20.9486
617 1X6V ADP 20.9486
618 5KDO GDP 20.9486
619 1GP2 GDP 20.9486
620 3ZS9 ADP ALF 21.0526
621 3WYF GTP 21.8487
622 3A4M ADP 22.3077
623 5X40 ACP 22.5296
624 1IBR GNP 22.5296
625 3KTA AP5 22.5434
626 5UQW GDP 23.2804
627 5OCG GNP 23.2804
628 5TB5 GDP 23.7838
629 5TAR GDP 23.7838
630 2HCJ GDP 24.3243
631 4U5X GNP 24.7191
632 5O74 GDP 25
633 3H4S ADP 25.1852
634 1XEX ATP 25.5814
635 2JHP SAH 25.6917
636 4K81 GTP 25.731
637 5O2T GSP 26.0355
638 5E95 GDP 26.1905
639 6D56 GNP 26.3473
640 6D59 GNP 26.3473
641 6D5J GNP 26.3473
642 6BVK GNP 26.3473
643 6D5H GNP 26.3473
644 6BVL GNP 26.3473
645 6BVJ GNP 26.3473
646 6BVI GNP 26.3473
647 6D5V GNP 26.3473
648 6D5E GNP 26.3473
649 6D55 GNP 26.3473
650 6D5G GNP 26.3473
651 1LFD GNP 26.3473
652 6BVM GNP 26.3473
653 6D5L GNP 26.3473
654 6D5M GNP 26.3473
655 5Z69 AGS 26.4822
656 2UZI GTP 26.506
657 1WQ1 AF3 26.506
658 1WQ1 GDP 26.506
659 1CLU DBG 26.506
660 3DDC GNP 26.506
661 1NVV GNP 26.506
662 5WLB GNP 26.506
663 1Z0K GTP 28.9855
664 2PEZ GGZ 29.6089
665 2PEZ DAT 29.6089
666 4CVN ADP 29.8429
667 3QF7 ANP 34
668 3EWA ANP 34.472
669 2GDJ ANP 41.1067
670 3FYH ADP 41.502
Pocket No.: 2; Query (leader) PDB : 4TL6; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4tl6.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4TL6; Ligand: ANP; Similar sites found with APoc: 5
This union binding pocket(no: 3) in the query (biounit: 4tl6.bio1) has 53 residues
No: Leader PDB Ligand Sequence Similarity
1 5KK4 44E None
2 5HV7 RBL 4.74308
3 3G5N PB2 5.13834
4 2ZJ5 ADP 5.92885
5 5XHA FRU 8.69565
Pocket No.: 4; Query (leader) PDB : 4TL6; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4tl6.bio1) has 53 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4TL6; Ligand: ANP; Similar sites found with APoc: 12
This union binding pocket(no: 5) in the query (biounit: 4tl6.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3NFD COA 1.30719
2 2V5K OXM 2.37154
3 3BXF 13P 3.16206
4 3ZPG 5GP 3.9267
5 1IXE COA 3.95257
6 6BT4 KPM 4.9505
7 4NAE 1GP 5.33333
8 3WWX DIA 6.59026
9 2IDO TMP 8.60215
10 4UP4 GAL NAG 9.88142
11 5D63 FUC GAL GLA 9.88142
12 5HP8 PYR 15.3226
Pocket No.: 6; Query (leader) PDB : 4TL6; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4tl6.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
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