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Receptor
PDB id Resolution Class Description Source Keywords
4RF7 2.1 Å EC: 2.7.3.3 CRYSTAL STRUCTURE OF DOUBLE-DOMAIN ARGININE KINASE FROM ANTH JAPONICAS IN COMPLEX WITH SUBSTRATE L-ARGININE ANTHOPLEURA JAPONICA DOUBLE DOMAIN TANDEM DOMAIN PHOSPHAGEN KINASE TRANSFERASE
Ref.: STRUCTURE OF A DOUBLE-DOMAIN PHOSPHAGEN KINASE REVE ASYMMETRIC ARRANGEMENT OF THE TANDEM DOMAINS. ACTA CRYSTALLOGR.,SECT.D V. 71 779 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ARG A:805;
A:807;
B:1006;
B:1005;
A:806;
B:1007;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
175.209 C6 H15 N4 O2 C(C[C...
ACT A:802;
A:804;
B:1003;
A:801;
A:803;
B:1002;
B:1004;
B:1001;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4RF7 2.1 Å EC: 2.7.3.3 CRYSTAL STRUCTURE OF DOUBLE-DOMAIN ARGININE KINASE FROM ANTH JAPONICAS IN COMPLEX WITH SUBSTRATE L-ARGININE ANTHOPLEURA JAPONICA DOUBLE DOMAIN TANDEM DOMAIN PHOSPHAGEN KINASE TRANSFERASE
Ref.: STRUCTURE OF A DOUBLE-DOMAIN PHOSPHAGEN KINASE REVE ASYMMETRIC ARRANGEMENT OF THE TANDEM DOMAINS. ACTA CRYSTALLOGR.,SECT.D V. 71 779 2015
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4RF8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4RF7 - ARG C6 H15 N4 O2 C(C[C@@H](....
3 4RF9 - ARG C6 H15 N4 O2 C(C[C@@H](....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4RF8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4RF7 - ARG C6 H15 N4 O2 C(C[C@@H](....
3 4RF9 - ARG C6 H15 N4 O2 C(C[C@@H](....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4RF8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4RF7 - ARG C6 H15 N4 O2 C(C[C@@H](....
3 4RF9 - ARG C6 H15 N4 O2 C(C[C@@H](....
4 4WOD - ARG C6 H15 N4 O2 C(C[C@@H](....
5 4WOE Kd = 3.8 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ARG; Similar ligands found: 42
No: Ligand ECFP6 Tc MDL keys Tc
1 ARG 1 1
2 DAR 1 1
3 CIR 0.735294 0.763158
4 AAR 0.705882 0.783784
5 ILO 0.615385 0.783784
6 3AR 0.595238 0.891892
7 4JK 0.585366 0.789474
8 NMM 0.585366 0.888889
9 VUR 0.585366 0.810811
10 HAR 0.585366 0.780488
11 VIO 0.581395 0.769231
12 WT2 0.571429 0.805556
13 DA2 0.55814 0.744186
14 2MR 0.545455 0.864865
15 2YH 0.545455 0.65
16 3KJ 0.545455 0.680851
17 1KJ 0.533333 0.744186
18 JM2 0.533333 0.731707
19 NRG 0.521739 0.622642
20 RPI 0.521739 0.64
21 2YJ 0.521739 0.619048
22 API 0.515152 0.611111
23 LN6 0.510638 0.725
24 HRG 0.5 0.941176
25 JM7 0.5 0.731707
26 2KJ 0.489796 0.727273
27 D20 0.489796 0.744186
28 AS1 0.489796 0.8
29 ORN 0.472222 0.757576
30 JM8 0.470588 0.714286
31 JM6 0.470588 0.697674
32 JM4 0.470588 0.697674
33 LYS ARG LYS ARG LYS ARG LYS ARG 0.463415 0.848485
34 MLZ 0.463415 0.65
35 JM5 0.461538 0.714286
36 DLY 0.447368 0.735294
37 DAB 0.441176 0.685714
38 LYS 0.435897 0.764706
39 0TF 0.428571 0.619048
40 2YG 0.42 0.619048
41 PG3 0.416667 0.756757
42 6CL 0.414634 0.638889
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4RF7; Ligand: ARG; Similar sites found with APoc: 66
This union binding pocket(no: 1) in the query (biounit: 4rf7.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 1VFS DCS 1.29534
2 4FFG 0U8 1.42276
3 5LIA 6XN 1.53203
4 2AMV BIN 1.54394
5 2QRK AMP 1.77665
6 5J5Z FAD 1.81452
7 4I54 1C1 1.983
8 2J5B TYE 2.01149
9 3FYH ADP 2.17391
10 3CW9 01A 2.18254
11 5O0J 8BR 2.20751
12 5T9E NAP 2.21402
13 3C3N FMN 2.24359
14 3BJU ATP 2.30326
15 2J07 FAD 2.38095
16 2J07 HDF 2.38095
17 4YDD MD1 2.4024
18 4YDD MGD 2.4024
19 5JCA FAD 2.46479
20 1UA4 AMP 2.63736
21 2GDJ ANP 2.65152
22 5WM2 SAL 2.65957
23 4YBN FAD 2.67857
24 4RPL FAD 2.75689
25 4RPL 3UC 2.75689
26 3NEM AMO 2.96804
27 1IYK MIM 3.06122
28 4TS1 TYR 3.1348
29 4HWS 1B3 3.16302
30 4TSK NDP 3.42857
31 4FHD 0TT 3.53261
32 4FHD EEM 3.53261
33 5XFV FMN 3.59281
34 3E85 BSU 3.79747
35 5FWJ MMK 3.82166
36 3AB4 LYS 3.93258
37 5U3B 7TD 4.01338
38 3O84 HTJ 4.04412
39 1PVN MZP 4.25532
40 3LKJ LKJ 4.25532
41 3ZNN 4WL 4.32277
42 3ZNN FAD 4.32277
43 5IVE 6E8 4.54545
44 1B4P GPS 4.60829
45 1MDB AMP DBH 4.82375
46 5FLJ QUE 4.83871
47 5W7C DAO FTT 5.03597
48 1B7Y FYA 5.14286
49 1JIL 485 5.2381
50 5X1M DHB 5.48523
51 2TPS TPS 5.72687
52 3REU ATP 5.78231
53 4L9Z COA 6.19469
54 4L9Z OXL 6.19469
55 3A5Z KAA 6.28272
56 2HHJ DG2 6.36704
57 2HHJ 3PG 6.36704
58 5A3T MMK 7.06861
59 2FB3 GTP 7.35294
60 2F5Z FAD 7.8125
61 3L5R 47X 8.19672
62 5W3K NDP 8.23529
63 1SBZ FMN 10.6599
64 5LDQ NAP 11.2994
65 5KVM THR TYR PHE ALA VAL LEU MET VAL SER 11.5789
66 2D0O ADP 20
Pocket No.: 2; Query (leader) PDB : 4RF7; Ligand: ARG; Similar sites found with APoc: 191
This union binding pocket(no: 2) in the query (biounit: 4rf7.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3EPO MP5 1.14379
2 2CDU ADP 1.32743
3 2J4D MHF 1.52381
4 5ENZ UDP 1.55844
5 3GD4 NAD 1.56556
6 3EI9 PL6 1.62037
7 2WH8 II2 1.69492
8 3EYA TDP 1.82149
9 1ZBQ NAD 1.83486
10 3ZIU LSS 1.88383
11 4O1M NAD 1.90476
12 3WBF NAP 1.96721
13 3COW 52H 1.99336
14 4A0S NAP 2.01342
15 2X5W K2B 2.04545
16 2NVK NAP 2.04918
17 4HXY NDP 2.05479
18 3V1Y NAD 2.07715
19 2QZZ NAP 2.20126
20 1C7O PPG 2.25564
21 6CI9 NAP 2.3166
22 2Q2V NAD 2.35294
23 2VYN NAD 2.39521
24 1GRO ICT 2.40385
25 5JDC NAP 2.43056
26 5K6A NAP 2.43056
27 4CMI NAP 2.43056
28 5JCJ NAP 2.43056
29 3JQF NAP 2.43056
30 4CM9 NAP 2.43056
31 5JDI NAP 2.43056
32 3JQ7 NAP 2.43056
33 4CM8 NAP 2.43056
34 3BMO NAP 2.43056
35 4CM4 NAP 2.43056
36 3BMQ NAP 2.43056
37 3JQG NAP 2.43056
38 3JQA NAP 2.43056
39 4CME NAP 2.43056
40 4CLO NAP 2.43056
41 3JQ9 NAP 2.43056
42 3JQB NAP 2.43056
43 1RF6 GPJ 2.57611
44 1RF6 S3P 2.57611
45 3I6I NDP 2.60116
46 2VZ0 NAP 2.61194
47 2VZ0 D64 2.61194
48 2WD7 NAP 2.61194
49 3VRY B43 2.64317
50 2WOX NDP 2.65849
51 2C2A ADP 2.71318
52 2WSB NAD 2.75591
53 2YAK OSV 2.80702
54 5X68 FAD 2.8133
55 2FQX GMP 2.83019
56 4X7R UDP 2.83976
57 4X7R 3YW 2.83976
58 4A2A ATP 2.86396
59 4A2B AGS 2.86396
60 4YRY NAD 2.89855
61 5ETJ IM5 3.08642
62 4EWN 0VR 3.16206
63 6FK3 PPI 3.17164
64 4E13 NAD 3.18021
65 5XWV 8H6 3.22581
66 5XWV NDP 3.22581
67 5EJ2 NAD 3.24675
68 1G2O IMH 3.35821
69 2ZYI STE 3.36842
70 4NEC SAH 3.40909
71 4NMC 2OP 3.48189
72 4NMC FAD 3.48189
73 1LUA NAP 3.48432
74 5G4L NDP 3.4965
75 2J0W ADP 3.56347
76 4O0L NDP 3.63636
77 2ZJ3 G6P 3.73333
78 4W6Z 8ID 3.7464
79 6CLV 6MB 3.78007
80 1WDK NAD 3.84615
81 2J8C U10 3.84615
82 3VZS CAA 3.89105
83 3VZS NAP 3.89105
84 5GQX GLC GLC GLC GLC GLC GLC GLC 3.89972
85 3QPB R1P 3.90071
86 2IRY DGT 3.9604
87 4WOP CTP 4
88 1KRH FAD 4.14201
89 4S28 SAH 4.16667
90 4S28 AIR 4.16667
91 3H4V DVP 4.16667
92 3H4V NAP 4.16667
93 4IPE ANP 4.17827
94 3CMC NAD 4.19162
95 1I7L ATP 4.20712
96 2DC1 NAD 4.23729
97 2UZH CDP 4.24242
98 4Y93 746 4.26009
99 3WGT FAD 4.32277
100 3P7I P7I 4.36137
101 3ORF NAD 4.38247
102 4ZGS NAD 4.40415
103 2DSA HPX 4.4335
104 4YAG NAI 4.49827
105 5UR0 NAD 4.58453
106 5MGZ SAH 4.66102
107 2V6K TGG 4.6729
108 5K8B PDG 4.71464
109 5SWB NAG BMA MAN MAN MAN MAN 4.83193
110 4ITU NAI 4.83271
111 2WE5 ADP 4.83871
112 4AMV F6R 4.92611
113 3TN7 NJP 5.05837
114 5NUL FMN 5.07246
115 5DH3 5BS 5.07937
116 1CER NAD 5.13595
117 1WN3 HXC 5.14706
118 1QF9 C5P 5.15464
119 1QF9 ADP 5.15464
120 1QF9 ALF 5.15464
121 4EPL JAI 5.16351
122 4ZUL UN1 5.26316
123 5ZZ6 NAD 5.28846
124 4KBY C2E 5.31401
125 1F6D UDP 5.31915
126 4Z87 GDP 5.33333
127 2ZAT NAP 5.38462
128 5T79 NDP 5.42169
129 1HYE NAP 5.43131
130 1FK8 NAD 5.44747
131 4BQO COA 5.44872
132 2POC BG6 5.44959
133 3HRD FAD 5.45455
134 5BJX NAD 5.46448
135 5BJX UDP 5.46448
136 2B4R NAD 5.50725
137 4TXI FAD 5.52846
138 3AY6 NAI 5.57621
139 5NXX 3Q7 5.59701
140 3FIU AMP 5.62249
141 5YSS NAD 5.85938
142 1VHT BA3 5.9633
143 2PQB GG9 5.98886
144 1RHC F42 ACN 6.06061
145 1PG4 COA 6.28834
146 1PG4 PRX 6.28834
147 4N70 2HX 6.40244
148 1EQ2 NAP 6.45161
149 1O94 ADP 6.5625
150 6F9Q NAD 6.61765
151 4MRT COA 6.66667
152 3WHB DCC 6.70103
153 2BRY FAD 6.84105
154 2JLD AG1 6.90476
155 5OLZ T4E 7.14286
156 1XG5 NAP 7.16846
157 4CQM NAP 7.37705
158 4B1V ATP 7.44681
159 3SJH LAR 7.46667
160 3SJU NDP 7.52688
161 5ODQ 9SB 7.56014
162 4Z0H NAD 7.78443
163 1J5P NAD 7.90514
164 3IID APR 8.05687
165 1L2T ATP 8.51064
166 1RM4 NDP 8.60534
167 1HEX NAD 8.69565
168 2CJF RP4 8.9172
169 2BD0 NAP 9.01639
170 1GZ6 NAI 9.40439
171 1XHL NDP 9.42761
172 3RJ5 NAD 9.44882
173 2II3 CAO 9.54198
174 4BCM T7Z 10.3053
175 3D3W NAP 10.6557
176 1XKQ NDP 10.7143
177 4KXL 6C6 11.1842
178 1R6N 434 11.8483
179 5KOR GDP 11.9002
180 5T2U NAP 12.0968
181 1Z6Z NAP 12.766
182 3QV1 NAD 13.4146
183 4P5E N6P 14.4737
184 5LXT 7AK 15.3846
185 4ZOH FAD 17.8571
186 3MN6 ATP 18.4492
187 5EPO TUD 20.6107
188 5EPO NAP 20.6107
189 1T3Q FAD 20.8333
190 2D0V PQQ 22.2222
191 1X1T NAD 25
Pocket No.: 3; Query (leader) PDB : 4RF7; Ligand: ARG; Similar sites found with APoc: 834
This union binding pocket(no: 3) in the query (biounit: 4rf7.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 4K3H 1OM None
2 6E2B PT7 None
3 1PJ6 FOL 0.835655
4 5X7Q GLC GLC GLC GLC GLC 0.97493
5 5X7Q GLC GLC GLC GLC 0.97493
6 1WLE SRP 0.998004
7 4PAB THG 1.11421
8 1KY8 NAP 1.1976
9 4O8A FAD 1.25348
10 1F52 ADP 1.28205
11 1VA6 P2S 1.35135
12 1VA6 ADP 1.35135
13 6C1S EFV 1.39276
14 6MVU K4V 1.39276
15 5KO1 6UY 1.41343
16 2GVJ DGB 1.42566
17 2Y6Q I7T 1.50754
18 5J75 6GQ 1.51515
19 2IW3 ADP 1.5213
20 5F7U GLC GLC 1.53203
21 4QDC ASD 1.53846
22 4PTZ FMN 1.57068
23 3LVW GSH 1.5896
24 3Q60 ATP 1.61725
25 4KCL H4B 1.65877
26 4KCL H44 1.65877
27 4XPQ FUL 1.67131
28 4GV4 MEJ 1.68067
29 1X7D ORN 1.71429
30 5T8O 76Z 1.7192
31 2WN6 NDP 1.72786
32 3OV6 MK0 1.76322
33 1E1O LYS 1.78571
34 1PN4 HDC 1.78571
35 1Q19 APC 1.78926
36 5MU6 MYA 1.79028
37 5MU6 KFK 1.79028
38 1Y7P RIP 1.79372
39 1ELI PYC 1.79949
40 5H9Y BGC BGC BGC BGC 1.8018
41 2XIQ MLC 1.81058
42 1NW4 IMH 1.81159
43 4WHZ 3NL 1.81818
44 5KJW 53C 1.87354
45 1Q8Y ADP 1.87668
46 2ZRU FMN 1.90217
47 2FUE M1P 1.9084
48 3QSB 743 1.91257
49 2C5S AMP 1.93705
50 1JGT APC 1.94932
51 1JGT CMA 1.94932
52 5NKB 8ZT 1.96078
53 4AAW R84 1.96078
54 5MJA 7O3 1.96721
55 1VHW ADN 1.97628
56 5F7R GLC GLC 1.9802
57 2XVD AS6 1.98676
58 4B2Z P5S 2.00893
59 4L80 1VU 2.01149
60 1F9V ADP 2.01729
61 3TTZ 07N 2.0202
62 1ED4 IPU 2.02703
63 1REQ DCA 2.04082
64 4GID 0GH 2.06186
65 4MP8 NAD 2.0649
66 4MP8 MLI 2.0649
67 5FPE 3TR 2.06718
68 3GE7 AFQ 2.07254
69 5TV6 PML 2.08333
70 4X3R 686 2.08914
71 5L13 6ZE 2.12766
72 2GJN NIS 2.13415
73 2GJN FMN 2.13415
74 4P8O 883 2.13904
75 4HWT 1B2 2.17918
76 3GD9 GLC BGC BGC BGC 2.17984
77 3IWJ NAD 2.18688
78 4UX9 ANP 2.1978
79 2NSX IFM 2.21328
80 4A0M NAD 2.21774
81 6GWR FEW 2.22222
82 3T4L ZEA 2.22222
83 2X2M X2M 2.2293
84 6GW1 CHO 2.2293
85 4I53 1C1 2.23464
86 5TA6 79D 2.23464
87 5UR1 YY9 2.2508
88 5JKG 6LF 2.2508
89 3TWD GOB 2.25225
90 3VET ADP 2.25694
91 3VET TOY 2.25694
92 3VET CP 2.25694
93 4ONA UW1 2.27273
94 5AE2 FAD 2.27964
95 5AE2 FYC 2.27964
96 3TDV GDP 2.28758
97 6GVZ CHO 2.29508
98 5W75 SUC 2.29592
99 2XGT NSS 2.29885
100 1MXG ACR 2.29885
101 3I3X U22 2.3166
102 1Q1R FAD 2.32019
103 3P7N FMN 2.32558
104 2ZW5 COA 2.32558
105 4GCZ FMN 2.33766
106 3ACL 3F1 2.36486
107 1VPM COA 2.36686
108 5OX6 A1Z 2.38095
109 5DRB 5FJ 2.4055
110 4RD0 GDP 2.40964
111 3TEG DAH 2.40964
112 4YRI 4JH 2.41228
113 1LYX PGA 2.41935
114 5C5H 4YB 2.42826
115 4DQ2 BTX 2.43902
116 5DBX ANP 2.43902
117 4Z24 FAD 2.45399
118 5GLT BGC GAL NAG GAL 2.46479
119 1M5W DXP 2.46914
120 2WZM NA7 2.4735
121 2QZS 250 2.47423
122 2QZS GLC 2.47423
123 2QZS ADP 2.47423
124 3E7O 35F 2.5
125 3VHE 42Q 2.50696
126 5UL4 SAM 2.50696
127 6FXR AKG 2.50696
128 3IAL PR8 2.50965
129 1B7H LYS NLE LYS 2.51451
130 5AYT L6Y 2.51572
131 2D6M LBT 2.51572
132 2R5V HHH 2.52101
133 5H2D ERG 2.52874
134 4ASE AV9 2.54958
135 3H5N ATP 2.54958
136 4ZH7 FUC GAL NAG GAL FUC 2.57827
137 5Z46 8XL 2.589
138 5XIJ 873 2.6
139 5XIJ ANP 2.6
140 1ZB6 GST 2.60586
141 1ZB6 DIN 2.60586
142 3A5Y KAA 2.6087
143 2YYY NAP 2.62391
144 4M38 SAH 2.62391
145 1OPK P16 2.62626
146 1EWF PC1 2.63158
147 4B0T ADP 2.63692
148 4U98 ACP 2.64317
149 3MTX PGT 2.64901
150 2J7T 274 2.64901
151 4J36 1HR 2.6506
152 2GC0 PAN 2.65957
153 3IGO ANP 2.6749
154 2G30 ALA ALA PHE 2.71318
155 3QH2 3NM 2.71493
156 3HXU A5A 2.72109
157 2YBQ UP2 2.73973
158 2YBQ SAH 2.73973
159 5O1I 9GH 2.73973
160 6GQM F8H 2.7439
161 4E1Z 0MX 2.74914
162 1T7Q COA 2.75081
163 1T7Q 152 2.75081
164 2NXE SAM 2.75591
165 3G1Z AMP 2.76074
166 1COY FAD 2.76134
167 4MSG 2C6 2.76498
168 3WYJ H78 2.7668
169 3ZJX BOG 2.76817
170 4NW6 2NS 2.78638
171 4O9S 2RY 2.7907
172 5F7J ADE 2.8125
173 4YDQ HFG 2.8169
174 4YDQ ANP 2.8169
175 2Z3U CRR 2.82353
176 1OJZ NAD 2.83019
177 2YPI PGA 2.83401
178 3UDZ ADP 2.83976
179 1RYD GLC 2.84238
180 5D9G GLU ASN LEU TYR PHE GLN 2.84553
181 4AG8 AXI 2.8481
182 4U0I 0LI 2.85714
183 1IA9 ANP 2.85714
184 4J3L AJ5 2.85714
185 5JFL NAD 2.8626
186 2OJW ADP 2.86458
187 1IIU RTL 2.87356
188 4NV7 COA 2.88462
189 4BTV RB3 2.90698
190 2RCU BUJ 2.90965
191 4YC0 5OF 2.92887
192 3WUD GLC GAL 2.94118
193 5LRT ADP 2.95276
194 5DG2 GAL GLC 2.96296
195 3PE2 E1B 2.96736
196 1CF2 NAP 2.96736
197 4J7H TLO 2.9724
198 4PJT 2YQ 2.97297
199 6FL8 ADP 2.97872
200 6FL8 TIY 2.97872
201 2FFU UDP 2.99401
202 3WDX BGC BGC GLC 3.02013
203 1PHK ATP 3.02013
204 2PR5 FMN 3.0303
205 4D7E FAD 3.0303
206 3I8T LBT 3.04878
207 5F3I 5UJ 3.05556
208 5HCY 60D 3.06407
209 2PNC CLU 3.06407
210 4IEN GDP 3.06748
211 5I7A 68Q 3.06748
212 3THR C2F 3.07167
213 1PI5 SM2 3.07263
214 4I3V NAD 3.07377
215 4XV1 904 3.08219
216 5ZJ5 NAI 3.08642
217 1IZE IVA VAL VAL STA ALA STA 3.09598
218 4TW7 37K 3.125
219 4P8K FAD 3.125
220 4P8K 38C 3.125
221 3IU9 T07 3.125
222 1EFY BZC 3.14286
223 3TCT 3MI 3.14961
224 2OO8 RAJ 3.15457
225 5QIN J2V 3.16456
226 1LDN NAD 3.16456
227 2VPE ALA ARG THR MLY GLN THR ALA 3.1746
228 5A6N U7E 3.18021
229 4M69 ANP 3.18021
230 3R96 ACO 3.19149
231 3R96 AMP 3.19149
232 5VCV 1N1 3.21543
233 4RYV ZEA 3.22581
234 5HW4 SAM 3.22581
235 2QM9 TDZ 3.22581
236 4CQE CQE 3.23741
237 1LNM DTX 3.26087
238 3KJD 78P 3.26087
239 3A7R LAQ 3.2641
240 3IES M24 3.26679
241 3HKW IX6 3.27022
242 1H9G COA MYR 3.29218
243 5VAD 91Y 3.29457
244 5VAD PRO 3.29457
245 4FL3 ANP 3.30709
246 5WO4 B7V 3.31126
247 2Z6J FMN 3.31325
248 1ZM1 BGC BGC BGC 3.3195
249 4MIB 28M 3.33333
250 2A1L PCW 3.33333
251 5OF1 SAL 3.33333
252 2GTF P1R 3.33333
253 4G6I RS3 3.33333
254 2GV8 NDP 3.3557
255 2CSN CKI 3.367
256 6CC0 EWM 3.37553
257 3TW1 AHN 3.37553
258 3GLC R5P 3.38983
259 3TA2 ATP 3.38983
260 2ABS ACP 3.39426
261 5MW8 ATP 3.39703
262 2DXU BT5 3.40426
263 1WPY BTN 3.40426
264 5LY1 PPI 3.41207
265 4RLE 2BA 3.4188
266 2V0U FMN 3.42466
267 1RE8 BD2 3.42857
268 5DX0 SFG 3.4384
269 6ARJ BW4 3.4384
270 6ARJ SAH 3.4384
271 5DWQ SFG 3.4384
272 4RFR RHN 3.44828
273 2E5A LAQ 3.45821
274 6C0T EE4 3.45821
275 3OYZ ACO 3.4642
276 5G48 1FL 3.47594
277 5F7V GLC GLC GLC GLC 3.5
278 5EWK P34 3.5
279 2VJM COA 3.50467
280 3MVH WFE 3.50877
281 3EWK FAD 3.52423
282 5UGH 8AJ 3.52645
283 5IXG OTP 3.5503
284 3G6K FAD 3.57143
285 6FOF LAT 3.57143
286 5YJS SAL 3.58974
287 2Z77 HE7 3.59712
288 3ZF8 GDP 3.60656
289 4OYA 1VE 3.61702
290 2H8H H8H 3.62117
291 3STD MQ0 3.63636
292 5TUF FAD 3.66748
293 5TUF TDC 3.66748
294 2CER PGI 3.68098
295 4MKG AP5 3.68664
296 2RIO ADP 3.68664
297 5XQW 8EU 3.68664
298 5LUN ARG 3.69318
299 5LUN OGA 3.69318
300 5X8G S0N 3.71134
301 2RG0 CTT 3.72093
302 4GGL CJC 3.72093
303 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 3.7234
304 4IAW LIZ 3.7234
305 1U0A BGC BGC BGC BGC 3.73832
306 1W96 S1A 3.79061
307 1GZF NAD 3.79147
308 1GZF ADP 3.79147
309 1GZF NIR 3.79147
310 2JDR L20 3.80117
311 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 3.80117
312 5O9W AKG 3.81471
313 2QIA U20 3.81679
314 2RC5 FAD 3.82166
315 1QIN GIP 3.82514
316 4D5B ACX 3.83481
317 3G5D 1N1 3.84615
318 3PP0 03Q 3.84615
319 2QBU SAH 3.87931
320 3Q9O NAD 3.89408
321 2Z5Y HRM 3.89864
322 5HES 032 3.90879
323 4KBA 1QM 3.92749
324 5W4W 9WG 3.92749
325 3WG3 A2G GAL NAG FUC 3.93258
326 6CGD GNP 3.93443
327 6CGD AKN 3.93443
328 4L3L 5FI 3.94737
329 1UMZ BGC BGC XYS BGC XYS GAL 3.95683
330 4KYS VIB 3.98126
331 5G3Y ADP 3.9823
332 4CSV STI 4
333 1SBR VIB 4
334 2IU8 PLM 4.01069
335 4CS4 ANP 4.0146
336 4CS4 AXZ 4.0146
337 3PLS ANP 4.02685
338 4F4P 0SB 4.0293
339 5EJL C2E 4.03226
340 1I1E DM2 4.039
341 4I8P NAD 4.039
342 3CBC DBS 4.0404
343 4DXD 9PC 4.0404
344 3GC8 B45 4.05405
345 4ZU4 4TG 4.05405
346 2ZHL NAG GAL GAL NAG 4.05405
347 6BHV DQV 4.05904
348 4I9B NAD 4.0619
349 5KR7 6X9 4.08719
350 3TPV ADE 4.09091
351 6ES0 BW8 4.10095
352 3SXS PP2 4.10448
353 4OTH DRN 4.10557
354 6D6L FY4 4.11765
355 4FXQ G9L 4.13043
356 5Y4R C2E 4.13793
357 5LYH 7B8 4.14508
358 1S3G AP5 4.14747
359 5BVE 4VG 4.15512
360 5X5U NAD 4.15842
361 5DQ8 FLF 4.16667
362 2WQN ADP 4.19355
363 3NZ1 3NY 4.21456
364 1CLU DBG 4.21687
365 1QKQ MAN 4.22535
366 2I74 MAN MAN MAN MAN 4.2328
367 4D06 NAR 4.24028
368 6C5F 7L9 4.2735
369 3EFS BTN 4.29185
370 2XK9 XK9 4.34783
371 5UXH GFB 4.35967
372 2BGS NDP 4.36047
373 2P1M IHP 4.375
374 1WW5 SGA BGC 4.375
375 2P1O IHP 4.375
376 2P1O NLA 4.375
377 3VV1 GAL FUC 4.375
378 1LSH PLD 4.38871
379 1KZN CBN 4.39024
380 3E8N VRA 4.39883
381 3E8N ATP 4.39883
382 4EMV 0R9 4.42478
383 5CSS G3P 4.42478
384 2RKV COA 4.43459
385 2RKV ZBA 4.43459
386 5MY8 RXZ 4.43864
387 2HK5 1BM 4.44444
388 1LBF 137 4.45344
389 3QRC SCR 4.4586
390 5F6U 5VK 4.4586
391 3P2H NOO 4.47761
392 5KXQ GDP 4.51977
393 2WEI VGG 4.52962
394 4NFN 2KC 4.53074
395 4HIA FMN 4.54545
396 4Y24 TD2 4.54545
397 4FJU NAI 4.5584
398 4FJU GLV 4.5584
399 1M5B BN1 4.56274
400 2FY3 CHT 4.57516
401 3RGA LSB 4.59364
402 5MRH Q9Z 4.5977
403 1QY1 PRZ 4.5977
404 3CM2 X23 4.61538
405 4HY1 19X 4.61538
406 3T1A 5MA 4.61812
407 6EWZ APC 4.64135
408 2VL1 GLY GLY 4.64135
409 3DLG GWE 4.64286
410 5YK1 ANP 4.64602
411 1XK9 P34 4.65116
412 1ULE GLA GAL NAG 4.66667
413 5NIU 8YZ 4.6875
414 5VM0 9EG 4.6875
415 5GM9 CBK 4.69484
416 1QCA FUA 4.69484
417 5GP0 GPP 4.69799
418 1V9N NDP 4.72222
419 5OQW A4E 4.72441
420 2VDF OCT 4.74308
421 4X6F 3XU 4.7619
422 3KYF 5GP 5GP 4.7619
423 5JGA 6KC 4.7619
424 1ZDQ MSM 4.7619
425 4TXE 38F 4.7619
426 1YKD CMP 4.77387
427 6CDO ALA VAL GLY ILE GLY ALA VAL PHE 4.78261
428 1H4H XYP XYS XYP 4.78469
429 4TWP AXI 4.79705
430 5AIG VPR 4.8
431 2WKQ FMN 4.81928
432 3B82 NAD 4.83092
433 5N2F 8HW 4.83871
434 5AXH GLC GLC GLC GLC 4.85437
435 5VNF VAL THR SER VAL VAL 4.87465
436 2B3D FAD 4.90196
437 1KRR ACO 4.92611
438 3GD8 GOL 4.93274
439 3SLS ANP 4.93421
440 4L9I 8PR 4.96032
441 2WXD E18 4.99002
442 5KY9 GDP 5
443 5F7N NAG GAL FUC FUC A2G 5
444 5F7Y GLC GAL NAG GAL FUC A2G 5
445 3BXO UPP 5.02092
446 5KVA SAM 5.03597
447 2BO4 FLC 5.03778
448 2BVE PH5 5.04202
449 5WL1 CUY 5.05051
450 5WL1 D3D 5.05051
451 4L4V 1VY 5.05051
452 5U98 1KX 5.05051
453 2PVN P63 5.11364
454 1GQG DCD 5.14286
455 5FBN 5WF 5.16605
456 5DYO FLU 5.18868
457 4ZS4 ATP 5.21173
458 4WN5 MVC 5.21739
459 5XIO HFG 5.22088
460 1SLT NDG GAL 5.22388
461 1QD1 FON 5.23077
462 5H04 NAI 5.2506
463 4REP FAD 5.25253
464 6B3V ANP 5.26316
465 6B3V 7DQ 5.26316
466 1K97 ASP 5.27473
467 1K97 CIR 5.27473
468 2I7N ACO 5.27778
469 5T8U LPA 5.27778
470 1KZL CRM 5.28846
471 3ZXR IQ1 5.34979
472 3ZXR P3S 5.34979
473 4G31 0WH 5.35117
474 4WNK 453 5.35117
475 4BVA T3 5.37313
476 5Y72 DST 5.37313
477 5ACM MBT 5.40541
478 2OFV 242 5.41516
479 4BUY F37 5.41667
480 4C0X FMN 5.41872
481 4C0X AQN 5.41872
482 3BW2 FMN 5.42005
483 5AE9 OKO 5.43176
484 1AKY AP5 5.45455
485 5C83 4YN 5.45455
486 5XVG 8FX 5.46075
487 1QD0 RR6 5.46875
488 2GQS C2R 5.48523
489 2AG4 LP3 5.4878
490 2AG4 OLA 5.4878
491 2QCS ANP 5.49828
492 3LXK MI1 5.50459
493 5XDT ZI7 5.51948
494 5XDT MB3 5.51948
495 4WVO 3UZ 5.52486
496 5UR6 8KM 5.52486
497 1X54 4AD 5.52995
498 5C3R HMU 5.53936
499 5C3R AKG 5.53936
500 3FW4 CAQ 5.61798
501 1WUB OTP 5.61798
502 6E08 NAP 5.63107
503 4K55 H6P 5.64516
504 1SU2 ATP 5.66038
505 4U0W 16G 5.69106
506 4IZY 1J2 5.69106
507 1PZO CBT 5.70342
508 3LTW HLZ 5.71429
509 3KV8 FAH 5.7554
510 1K9J NAG MAN MAN MAN NAG 5.7554
511 4WUP 3UF 5.76923
512 3MF2 AMP 5.78035
513 6B92 SAH 5.78231
514 1UNB AKG 5.78778
515 1UNB PN1 5.78778
516 6A1G 9OL 5.83333
517 5O3Q CMP 5.83333
518 5SVV FMN 5.83942
519 5TVF CGQ 5.88235
520 1VJY 460 5.94059
521 1V0C ACO 5.94059
522 1V0C KNC 5.94059
523 6MPT C30 5.94406
524 5KD6 6C7 5.96659
525 5KD6 LBU 5.96659
526 4XMF HSM 5.97826
527 6C7Y ADP 5.98291
528 3TAO PGH 5.99251
529 1KOR SIN 6
530 1KOR ARG 6
531 1KOR ANP 6
532 3ZXE PGZ 6.01504
533 4X9X OLA 6.02007
534 2CUL FAD 6.03448
535 4X8O AP5 6.07477
536 1NYW DAU 6.09137
537 2ART LPA AMP 6.10687
538 1UYY BGC BGC 6.10687
539 5HWV MBN 6.15385
540 6GBV FMN 6.16438
541 3HCH RSM 6.16438
542 4KOT CE3 6.17284
543 4PYW ACE THR THR ALA ILE NH2 6.18812
544 5IXH OTP 6.21118
545 5LI1 ANP 6.21469
546 4RT1 C2E 6.25
547 4CO3 ATP 6.25
548 4LWP SAH 6.25
549 2VSL MAA LYS PRO PHE 6.25
550 5LI9 ACP 6.28571
551 4XTX 590 6.2963
552 5V59 8X1 6.31579
553 3LGS ADE 6.36704
554 3LGS SAH 6.36704
555 5N87 N66 6.38978
556 5DEY 59T 6.39731
557 2C78 PUL 6.41975
558 1N9L FMN 6.42202
559 2YVJ NAI 6.42202
560 4QPL V3L 6.45161
561 5WAN FMN 6.45161
562 2XXP DSL 6.53266
563 5DMZ ADP 6.57534
564 5D48 L96 6.57895
565 2X34 UQ8 6.62983
566 4UWJ 7L5 6.63391
567 4UWJ MYA 6.63391
568 3BXF FBP 6.66667
569 2X32 OTP 6.70391
570 1TT8 PHB 6.70732
571 2XMY CDK 6.71141
572 4LA7 A1O 6.73575
573 1N07 FMN 6.74847
574 1JJE BYS 6.75676
575 3PVW QRX 6.75676
576 1ZNY GDP 6.76329
577 5CLO NS8 6.77966
578 5NWD 9C8 6.80628
579 1T36 ADP 6.82451
580 1T36 U 6.82451
581 5NDF LU2 6.83012
582 5NDF UDP 6.83012
583 5ALC TIQ 6.83761
584 5JNN 6LM 6.84211
585 3PFG SAM 6.84411
586 3PFG TLO 6.84411
587 5TKJ ALA VAL GLY ILE GLY ALA VAL PHE 6.84932
588 2VFT SOR 6.87204
589 4BFM ANP 6.88623
590 2NS1 ADP 6.89655
591 4CNK FAD 6.90537
592 2Z6D FMN 6.92308
593 2YMZ LAT 6.92308
594 2XCG XCG 6.92308
595 2OBD 2OB 6.93277
596 2ET1 GLV 6.96517
597 12AS AMP 6.9697
598 1MFI FHC 7.01754
599 2NZ2 CIR 7.02179
600 4LIT AKG 7.12531
601 1WOR RED 7.14286
602 4USI ATP 7.14286
603 5L9N ATP 7.14286
604 1VCE SAH 7.16981
605 2RDE C2E 7.17131
606 5MW4 5JU 7.18563
607 4YLZ LAT NAG GAL 7.18954
608 1YEJ PNF 7.20721
609 3AGC RCC 7.24638
610 2UX9 FMN 7.24638
611 5L4R CPT 7.24638
612 5VM6 9EG 7.29927
613 1F5F DHT 7.31707
614 3D91 REM 7.33138
615 2EQA AMP 7.38636
616 3RWP ABQ 7.3955
617 5LVP ATP 7.3955
618 6GNO XDI 7.40741
619 4H03 NAD 7.46667
620 4WUJ FMN 7.48299
621 6AYU MLI 7.4928
622 1S4M LUM 7.50853
623 1WNG SAH 7.54717
624 2J9C ATP 7.56302
625 2J9D ADP 7.56302
626 1MDC PLM 7.57576
627 2QHS OCA 7.59494
628 5H9P TD2 7.59494
629 4I9A NCN 7.63889
630 1OUK 084 7.65027
631 2JEN GLC GLC XYS XYS 7.66284
632 4Q0P 0MK 7.69231
633 2Z6C FMN 7.75194
634 4LOO SB4 7.75623
635 2ZTG A5A 7.79944
636 3V8S 0HD 7.80488
637 4ITH RCM 7.82313
638 3ILR IXD 7.83784
639 3ILR SGN 7.83784
640 6DW2 HD4 7.84314
641 4Y8D 49J 7.85714
642 3LXN MI1 7.86164
643 6G9I CXX 7.87879
644 5DLY SAH 7.89474
645 5DLY 5D7 7.89474
646 3A3B RBF 7.89474
647 3A3B FMN 7.89474
648 5OCG 9R5 7.93651
649 3QXV MTX 7.93651
650 5ODY 9SK 7.97101
651 3W0O HY0 8.02292
652 3W0O ADP 8.02292
653 4P5Z Q7M 8.03324
654 4M5S GLY GLU ARG THR ILE PRO ILE THR ARG GLU 8.04598
655 3VKX T3 8.04598
656 5UKL SIX 8.06452
657 3APT FAD 8.06452
658 2YNE YNE 8.07292
659 2YNE NHW 8.07292
660 3M3E GAL A2G NPO 8.07453
661 4NAT 2W5 8.125
662 4NAT ADP 8.125
663 4YZC STU 8.14815
664 1A78 TDG 8.20895
665 4FK7 P34 8.29694
666 4ZTD ALA GLY ALA GLY ALA 8.3004
667 3TKI S25 8.35913
668 6B2M COA 8.39161
669 2HKA C3S 8.46154
670 1KDK DHT 8.47458
671 1LO8 4CA 8.51064
672 2AAZ UMP 8.51735
673 2QHV OC9 8.57143
674 3T50 FMN 8.59375
675 5H2U 1N1 8.61423
676 5BW4 SAM 8.61423
677 2TPI ILE VAL 8.62069
678 6GG9 FMN 8.64198
679 6FA4 D1W 8.67052
680 2WSA 646 8.6758
681 2WSA MYA 8.6758
682 2YJ0 420 8.69565
683 1HXD BTN 8.72274
684 5E2N V14 8.74525
685 2FTB OLA 8.8
686 4EIL UMP 8.83392
687 1OG1 TAD 8.84956
688 4USF 6UI 8.88158
689 3ML1 MGD 8.88889
690 1DZK PRZ 8.9172
691 1GPM AMP 8.95238
692 5DKK FMN 8.96552
693 5HA0 LTD 8.97436
694 4R4U COA 8.99654
695 4L4J NAG NAG BMA MAN NAG 9.04977
696 4WO4 JLS 9.12409
697 3L9R L9Q 9.18367
698 3L9R L9R 9.18367
699 3E2M E2M 9.18919
700 3VZ3 NAP 9.19037
701 4QAC KK3 9.21659
702 4Q4K FMN 9.2437
703 2Y6O 1N1 9.27835
704 6GIN IR2 9.30233
705 4MOB ADP 9.33735
706 2RDQ AKG 9.375
707 4MNS 2AX 9.43396
708 3QFA FAD 9.48276
709 4R3U 3HC 9.49367
710 4R3U 3KK 9.49367
711 5JIC N7E 9.52381
712 5JIC ADP 9.52381
713 4YSX FAD 9.61539
714 2A9K NAD 9.62567
715 1O51 ADP 9.64912
716 3OQJ 3CX 9.72763
717 6HTO 5AD 9.75
718 6HTO MET 9.75
719 2J3M PRI 9.96504
720 2J3M ATP 9.96504
721 3SAO DBH 10
722 4F07 FAD 10
723 3SAO NKN 10
724 4XSH NAI 10.0559
725 4WK1 2BA 10.0775
726 4MO4 ACP 10.2426
727 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 10.2679
728 2BFR ADP 10.4167
729 4QYN RTL 10.5263
730 2XBP ATP 10.6195
731 5JZJ AN2 10.7744
732 3ESS 18N 10.8696
733 1SW0 PGA 10.8871
734 4Q5H ANP 10.9195
735 1ERB ETR 10.929
736 3E9I XAH 10.9533
737 4KS7 X4Z 10.9589
738 1KGI T4A 11.0236
739 5VC5 96M 11.0727
740 2ZMF CMP 11.1111
741 1QDS PGA 11.1554
742 6BE3 NAG 11.5207
743 1BC5 ACE ASN TRP GLU THR PHE 11.5242
744 2YKL NLD 11.5741
745 3ORK AGS 11.5756
746 2F3R G5P 11.5942
747 4ONT SIA GAL BGC 11.6279
748 2YAB AMP 11.6343
749 4H2X G5A 11.6505
750 4H2W 5GP 11.6505
751 4BX7 B4F 11.7188
752 5UIU 8CG 11.7647
753 6CAY ERG 11.8343
754 3KYG 5GP 5GP 11.8943
755 3DZ6 M8E 11.9403
756 1I7M CG 11.9403
757 5IOK ACE GLN THR ALA ARG KCR SER THR 11.9718
758 4MKF AP5 11.9816
759 5XLY C2E 12.0301
760 3FUU ADN 12.1771
761 2YC5 6BC 12.2807
762 3LF0 ATP 12.2807
763 2AGC DAO 12.3457
764 1GT4 UNA 12.5786
765 5EYP LOC 12.5843
766 4FG8 ATP 12.6984
767 3OJI PYV 12.6984
768 3H0L ADP 12.7615
769 1W8S FBP 12.9278
770 2NNQ T4B 12.9771
771 3FHI ANP 12.987
772 4IPH 1FJ 13.0081
773 4LRJ ANP 13.0178
774 3EM0 CHD 13.0435
775 1P1C SAH 13.0653
776 3WV6 GAL BGC 13.1757
777 3WV6 GAL GLC 13.1757
778 4NG2 OHN 13.2743
779 2ICK DMA 13.3047
780 4NU0 AP5 13.3641
781 1ZY5 ANP 13.5314
782 3WUC GLC GAL 13.8686
783 2E0N SAH 13.8996
784 4OCT AKG 13.964
785 1SDW IYT 14.0127
786 5ML3 DL3 14.094
787 3TAY MN0 14.1104
788 5DEX 5E0 14.1343
789 3OYW TDG 14.1791
790 2GJ5 VD3 14.1975
791 3O9L LPN 14.2045
792 3G08 FEE 14.386
793 4FE2 AIR 14.5098
794 1NMK SFM 14.5455
795 4ZSI GLP 14.6199
796 5W10 CMP 14.8718
797 1OPB RET 14.9254
798 5KY3 GFB 15
799 5COU ATP 15.2941
800 5LXT GTP 15.3846
801 5FM0 WAQ 15.3846
802 5XEG AKG 15.5844
803 5A89 FMN 16.0256
804 5A89 ADP 16.0256
805 5TBM 79A 16.5217
806 5EFW FMN 16.6667
807 4EWH T77 17.0909
808 1C4Q GLA GAL BGC 17.3913
809 3NCQ ATP 17.6471
810 5DJT FMN 18.0328
811 5DJU FMN 18.0328
812 1V3S ATP 18.1034
813 6A63 LAT 18.1159
814 1IS3 LAT 19.2593
815 1KQW RTL 19.403
816 3N0Y APC 20.1117
817 3IWD M2T 20.5882
818 4R38 RBF 20.7143
819 4EES FMN 20.8696
820 5L83 ASP TRP GLU ILE VAL 21.4286
821 3CF6 SP1 21.5569
822 3RF4 FUN 22.4138
823 3RUG DB6 22.549
824 5KEW 6SB 23.4043
825 3IS2 FAD 24.026
826 3D72 FAD 24.8322
827 6H39 FGY 27.2358
828 4H2V AMP 28.1818
829 3NV3 GAL NAG MAN 28.9855
830 2GU8 796 30
831 4WB6 ATP 30
832 1UW1 ADP 30
833 4WB7 ATP 30
834 4XIZ LPP 32.8571
Pocket No.: 4; Query (leader) PDB : 4RF7; Ligand: ARG; Similar sites found with APoc: 66
This union binding pocket(no: 4) in the query (biounit: 4rf7.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1KNR FAD 1.48148
2 4Y30 49L 1.7094